-- dump date   	20140620_054422
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1298917000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1298917000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1298917000003	putative catalytic residues [active]
1298917000004	putative nucleotide binding site [chemical binding]; other site
1298917000005	putative aspartate binding site [chemical binding]; other site
1298917000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1298917000007	dimer interface [polypeptide binding]; other site
1298917000008	putative threonine allosteric regulatory site; other site
1298917000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1298917000010	putative threonine allosteric regulatory site; other site
1298917000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1298917000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1298917000013	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1298917000014	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1298917000015	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917000016	catalytic residue [active]
1298917000017	hypothetical protein; Validated; Region: PRK02101
1298917000018	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1298917000019	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1298917000020	transaldolase-like protein; Provisional; Region: PTZ00411
1298917000021	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1298917000022	active site
1298917000023	dimer interface [polypeptide binding]; other site
1298917000024	catalytic residue [active]
1298917000025	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1298917000026	MPT binding site; other site
1298917000027	trimer interface [polypeptide binding]; other site
1298917000028	hypothetical protein; Provisional; Region: PRK10659
1298917000029	hypothetical protein; Provisional; Region: PRK10236
1298917000030	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1298917000031	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1298917000032	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1298917000033	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1298917000034	nucleotide binding site [chemical binding]; other site
1298917000035	chaperone protein DnaJ; Provisional; Region: PRK10767
1298917000036	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1298917000037	HSP70 interaction site [polypeptide binding]; other site
1298917000038	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1298917000039	substrate binding site [polypeptide binding]; other site
1298917000040	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1298917000041	Zn binding sites [ion binding]; other site
1298917000042	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1298917000043	dimer interface [polypeptide binding]; other site
1298917000044	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917000045	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917000046	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1298917000047	substrate binding pocket [chemical binding]; other site
1298917000048	dimerization interface [polypeptide binding]; other site
1298917000049	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1298917000050	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1298917000051	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1298917000052	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1298917000053	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
1298917000054	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1298917000055	active site
1298917000056	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1298917000057	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1298917000058	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1298917000059	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1298917000060	Helix-turn-helix domain; Region: HTH_36; pfam13730
1298917000061	fimbrial protein BcfA; Provisional; Region: PRK15187
1298917000062	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
1298917000063	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917000064	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917000065	outer membrane usher protein; Provisional; Region: PRK15193
1298917000066	PapC N-terminal domain; Region: PapC_N; pfam13954
1298917000067	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1298917000068	PapC C-terminal domain; Region: PapC_C; pfam13953
1298917000069	fimbrial protein BcfD; Provisional; Region: PRK15189
1298917000070	fimbrial protein BcfE; Provisional; Region: PRK15190
1298917000071	fimbrial protein BcfF; Provisional; Region: PRK15191
1298917000072	fimbrial chaperone BcfG; Provisional; Region: PRK15192
1298917000073	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917000074	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917000075	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1298917000076	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1298917000077	catalytic residues [active]
1298917000078	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1298917000079	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917000080	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917000081	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1298917000082	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1298917000083	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1298917000084	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1298917000085	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1298917000086	active site
1298917000087	metal binding site [ion binding]; metal-binding site
1298917000088	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1298917000089	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
1298917000090	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1298917000091	Sulfatase; Region: Sulfatase; pfam00884
1298917000092	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1298917000093	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917000094	FeS/SAM binding site; other site
1298917000095	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1298917000096	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1298917000097	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1298917000098	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1298917000099	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1298917000100	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917000101	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1298917000102	putative dimerization interface [polypeptide binding]; other site
1298917000103	putative alpha-glucosidase; Provisional; Region: PRK10658
1298917000104	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1298917000105	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
1298917000106	putative active site [active]
1298917000107	putative catalytic site [active]
1298917000108	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1298917000109	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1298917000110	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1298917000111	active site
1298917000112	Riboflavin kinase; Region: Flavokinase; smart00904
1298917000113	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1298917000114	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1298917000115	active site
1298917000116	HIGH motif; other site
1298917000117	nucleotide binding site [chemical binding]; other site
1298917000118	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1298917000119	active site
1298917000120	KMSKS motif; other site
1298917000121	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1298917000122	tRNA binding surface [nucleotide binding]; other site
1298917000123	anticodon binding site; other site
1298917000124	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1298917000125	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1298917000126	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1298917000127	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1298917000128	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1298917000129	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1298917000130	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1298917000131	active site
1298917000132	tetramer interface [polypeptide binding]; other site
1298917000133	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1298917000134	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917000135	active site
1298917000136	phosphorylation site [posttranslational modification]
1298917000137	intermolecular recognition site; other site
1298917000138	dimerization interface [polypeptide binding]; other site
1298917000139	Transcriptional regulator; Region: CitT; pfam12431
1298917000140	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1298917000141	PAS domain; Region: PAS; smart00091
1298917000142	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917000143	ATP binding site [chemical binding]; other site
1298917000144	Mg2+ binding site [ion binding]; other site
1298917000145	G-X-G motif; other site
1298917000146	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1298917000147	carboxyltransferase (CT) interaction site; other site
1298917000148	biotinylation site [posttranslational modification]; other site
1298917000149	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1298917000150	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
1298917000151	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1298917000152	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1298917000153	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1298917000154	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1298917000155	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
1298917000156	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1298917000157	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1298917000158	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1298917000159	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1298917000160	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1298917000161	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1298917000162	catalytic site [active]
1298917000163	subunit interface [polypeptide binding]; other site
1298917000164	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
1298917000165	carnitine operon protein CaiE; Provisional; Region: PRK13627
1298917000166	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1298917000167	putative trimer interface [polypeptide binding]; other site
1298917000168	putative metal binding site [ion binding]; other site
1298917000169	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
1298917000170	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1298917000171	substrate binding site [chemical binding]; other site
1298917000172	oxyanion hole (OAH) forming residues; other site
1298917000173	trimer interface [polypeptide binding]; other site
1298917000174	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
1298917000175	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
1298917000176	acyl-activating enzyme (AAE) consensus motif; other site
1298917000177	putative AMP binding site [chemical binding]; other site
1298917000178	putative active site [active]
1298917000179	putative CoA binding site [chemical binding]; other site
1298917000180	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
1298917000181	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1298917000182	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
1298917000183	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1298917000184	active site
1298917000185	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1298917000186	Ligand binding site [chemical binding]; other site
1298917000187	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1298917000188	ferredoxin-like protein FixX; Provisional; Region: PRK15449
1298917000189	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917000190	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1298917000191	putative substrate translocation pore; other site
1298917000192	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1298917000193	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1298917000194	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1298917000195	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1298917000196	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1298917000197	TrkA-N domain; Region: TrkA_N; pfam02254
1298917000198	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1298917000199	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1298917000200	folate binding site [chemical binding]; other site
1298917000201	NADP+ binding site [chemical binding]; other site
1298917000202	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1298917000203	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1298917000204	active site
1298917000205	metal binding site [ion binding]; metal-binding site
1298917000206	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1298917000207	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1298917000208	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1298917000209	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1298917000210	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1298917000211	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1298917000212	SurA N-terminal domain; Region: SurA_N; pfam09312
1298917000213	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1298917000214	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1298917000215	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1298917000216	OstA-like protein; Region: OstA; pfam03968
1298917000217	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1298917000218	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1298917000219	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1298917000220	putative metal binding site [ion binding]; other site
1298917000221	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1298917000222	HSP70 interaction site [polypeptide binding]; other site
1298917000223	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1298917000224	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1298917000225	active site
1298917000226	ATP-dependent helicase HepA; Validated; Region: PRK04914
1298917000227	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1298917000228	ATP binding site [chemical binding]; other site
1298917000229	putative Mg++ binding site [ion binding]; other site
1298917000230	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917000231	nucleotide binding region [chemical binding]; other site
1298917000232	ATP-binding site [chemical binding]; other site
1298917000233	DNA polymerase II; Reviewed; Region: PRK05762
1298917000234	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1298917000235	active site
1298917000236	catalytic site [active]
1298917000237	substrate binding site [chemical binding]; other site
1298917000238	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1298917000239	active site
1298917000240	metal-binding site
1298917000241	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1298917000242	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1298917000243	putative active site [active]
1298917000244	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1298917000245	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1298917000246	intersubunit interface [polypeptide binding]; other site
1298917000247	active site
1298917000248	Zn2+ binding site [ion binding]; other site
1298917000249	L-arabinose isomerase; Provisional; Region: PRK02929
1298917000250	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1298917000251	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1298917000252	trimer interface [polypeptide binding]; other site
1298917000253	putative substrate binding site [chemical binding]; other site
1298917000254	putative metal binding site [ion binding]; other site
1298917000255	ribulokinase; Provisional; Region: PRK04123
1298917000256	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1298917000257	N- and C-terminal domain interface [polypeptide binding]; other site
1298917000258	active site
1298917000259	MgATP binding site [chemical binding]; other site
1298917000260	catalytic site [active]
1298917000261	metal binding site [ion binding]; metal-binding site
1298917000262	carbohydrate binding site [chemical binding]; other site
1298917000263	homodimer interface [polypeptide binding]; other site
1298917000264	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1298917000265	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1298917000266	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917000267	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917000268	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1298917000269	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1298917000270	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1298917000271	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1298917000272	Walker A/P-loop; other site
1298917000273	ATP binding site [chemical binding]; other site
1298917000274	Q-loop/lid; other site
1298917000275	ABC transporter signature motif; other site
1298917000276	Walker B; other site
1298917000277	D-loop; other site
1298917000278	H-loop/switch region; other site
1298917000279	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1298917000280	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917000281	dimer interface [polypeptide binding]; other site
1298917000282	conserved gate region; other site
1298917000283	putative PBP binding loops; other site
1298917000284	ABC-ATPase subunit interface; other site
1298917000285	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917000286	dimer interface [polypeptide binding]; other site
1298917000287	conserved gate region; other site
1298917000288	putative PBP binding loops; other site
1298917000289	ABC-ATPase subunit interface; other site
1298917000290	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1298917000291	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1298917000292	transcriptional regulator SgrR; Provisional; Region: PRK13626
1298917000293	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1298917000294	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1298917000295	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1298917000296	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1298917000297	substrate binding site [chemical binding]; other site
1298917000298	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1298917000299	tartrate dehydrogenase; Region: TTC; TIGR02089
1298917000300	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1298917000301	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917000302	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1298917000303	putative substrate binding pocket [chemical binding]; other site
1298917000304	putative dimerization interface [polypeptide binding]; other site
1298917000305	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1298917000306	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1298917000307	putative valine binding site [chemical binding]; other site
1298917000308	dimer interface [polypeptide binding]; other site
1298917000309	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1298917000310	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1298917000311	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917000312	DNA binding site [nucleotide binding]
1298917000313	domain linker motif; other site
1298917000314	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1298917000315	dimerization interface [polypeptide binding]; other site
1298917000316	ligand binding site [chemical binding]; other site
1298917000317	mraZ protein; Region: TIGR00242
1298917000318	MraZ protein; Region: MraZ; pfam02381
1298917000319	MraZ protein; Region: MraZ; pfam02381
1298917000320	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1298917000321	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1298917000322	cell division protein FtsL; Provisional; Region: PRK10772
1298917000323	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1298917000324	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1298917000325	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1298917000326	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1298917000327	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1298917000328	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1298917000329	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1298917000330	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1298917000331	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1298917000332	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1298917000333	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1298917000334	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1298917000335	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1298917000336	Mg++ binding site [ion binding]; other site
1298917000337	putative catalytic motif [active]
1298917000338	putative substrate binding site [chemical binding]; other site
1298917000339	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1298917000340	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1298917000341	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1298917000342	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1298917000343	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1298917000344	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1298917000345	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1298917000346	cell division protein FtsQ; Provisional; Region: PRK10775
1298917000347	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1298917000348	Cell division protein FtsQ; Region: FtsQ; pfam03799
1298917000349	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1298917000350	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1298917000351	Cell division protein FtsA; Region: FtsA; pfam14450
1298917000352	cell division protein FtsZ; Validated; Region: PRK09330
1298917000353	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1298917000354	nucleotide binding site [chemical binding]; other site
1298917000355	SulA interaction site; other site
1298917000356	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
1298917000357	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1298917000358	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1298917000359	SecA regulator SecM; Provisional; Region: PRK02943
1298917000360	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1298917000361	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1298917000362	SEC-C motif; Region: SEC-C; pfam02810
1298917000363	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1298917000364	active site
1298917000365	8-oxo-dGMP binding site [chemical binding]; other site
1298917000366	nudix motif; other site
1298917000367	metal binding site [ion binding]; metal-binding site
1298917000368	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1298917000369	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1298917000370	active site
1298917000371	catalytic tetrad [active]
1298917000372	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1298917000373	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
1298917000374	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1298917000375	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1298917000376	CoA-binding site [chemical binding]; other site
1298917000377	ATP-binding [chemical binding]; other site
1298917000378	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1298917000379	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1298917000380	active site
1298917000381	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1298917000382	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1298917000383	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1298917000384	hypothetical protein; Provisional; Region: PRK10436
1298917000385	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1298917000386	Walker A motif; other site
1298917000387	ATP binding site [chemical binding]; other site
1298917000388	Walker B motif; other site
1298917000389	putative major pilin subunit; Provisional; Region: PRK10574
1298917000390	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1298917000391	Pilin (bacterial filament); Region: Pilin; pfam00114
1298917000392	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1298917000393	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1298917000394	dimerization interface [polypeptide binding]; other site
1298917000395	active site
1298917000396	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1298917000397	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1298917000398	amidase catalytic site [active]
1298917000399	Zn binding residues [ion binding]; other site
1298917000400	substrate binding site [chemical binding]; other site
1298917000401	regulatory protein AmpE; Provisional; Region: PRK10987
1298917000402	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1298917000403	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917000404	putative substrate translocation pore; other site
1298917000405	aromatic amino acid transporter; Provisional; Region: PRK10238
1298917000406	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1298917000407	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917000408	DNA-binding site [nucleotide binding]; DNA binding site
1298917000409	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1298917000410	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1298917000411	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1298917000412	dimer interface [polypeptide binding]; other site
1298917000413	TPP-binding site [chemical binding]; other site
1298917000414	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1298917000415	E3 interaction surface; other site
1298917000416	lipoyl attachment site [posttranslational modification]; other site
1298917000417	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1298917000418	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1298917000419	E3 interaction surface; other site
1298917000420	lipoyl attachment site [posttranslational modification]; other site
1298917000421	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1298917000422	E3 interaction surface; other site
1298917000423	lipoyl attachment site [posttranslational modification]; other site
1298917000424	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1298917000425	E3 interaction surface; other site
1298917000426	lipoyl attachment site [posttranslational modification]; other site
1298917000427	e3 binding domain; Region: E3_binding; pfam02817
1298917000428	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1298917000429	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1298917000430	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1298917000431	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917000432	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1298917000433	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1298917000434	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
1298917000435	putative inner membrane protein; Provisional; Region: PRK09823
1298917000436	Low molecular weight phosphatase family; Region: LMWPc; cl00105
1298917000437	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1298917000438	active site
1298917000439	hypothetical protein; Provisional; Region: PRK05248
1298917000440	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
1298917000441	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1298917000442	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1298917000443	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917000444	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1298917000445	spermidine synthase; Provisional; Region: PRK00811
1298917000446	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917000447	S-adenosylmethionine binding site [chemical binding]; other site
1298917000448	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1298917000449	multicopper oxidase; Provisional; Region: PRK10965
1298917000450	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1298917000451	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1298917000452	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1298917000453	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1298917000454	Trp docking motif [polypeptide binding]; other site
1298917000455	putative active site [active]
1298917000456	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1298917000457	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1298917000458	active site
1298917000459	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1298917000460	active site clefts [active]
1298917000461	zinc binding site [ion binding]; other site
1298917000462	dimer interface [polypeptide binding]; other site
1298917000463	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1298917000464	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1298917000465	Walker A/P-loop; other site
1298917000466	ATP binding site [chemical binding]; other site
1298917000467	Q-loop/lid; other site
1298917000468	ABC transporter signature motif; other site
1298917000469	Walker B; other site
1298917000470	D-loop; other site
1298917000471	H-loop/switch region; other site
1298917000472	inner membrane transport permease; Provisional; Region: PRK15066
1298917000473	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1298917000474	putative fimbrial protein StiH; Provisional; Region: PRK15297
1298917000475	fimbrial chaperone protein StiB; Provisional; Region: PRK15299
1298917000476	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917000477	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917000478	fimbrial protein StiA; Provisional; Region: PRK15300
1298917000479	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1298917000480	active pocket/dimerization site; other site
1298917000481	active site
1298917000482	phosphorylation site [posttranslational modification]
1298917000483	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1298917000484	putative active site [active]
1298917000485	putative metal binding site [ion binding]; other site
1298917000486	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1298917000487	tetramerization interface [polypeptide binding]; other site
1298917000488	active site
1298917000489	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1298917000490	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1298917000491	active site
1298917000492	ATP-binding site [chemical binding]; other site
1298917000493	pantoate-binding site; other site
1298917000494	HXXH motif; other site
1298917000495	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1298917000496	oligomerization interface [polypeptide binding]; other site
1298917000497	active site
1298917000498	metal binding site [ion binding]; metal-binding site
1298917000499	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1298917000500	catalytic center binding site [active]
1298917000501	ATP binding site [chemical binding]; other site
1298917000502	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
1298917000503	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1298917000504	active site
1298917000505	NTP binding site [chemical binding]; other site
1298917000506	metal binding triad [ion binding]; metal-binding site
1298917000507	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1298917000508	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1298917000509	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1298917000510	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1298917000511	active site
1298917000512	nucleotide binding site [chemical binding]; other site
1298917000513	HIGH motif; other site
1298917000514	KMSKS motif; other site
1298917000515	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1298917000516	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1298917000517	2'-5' RNA ligase; Provisional; Region: PRK15124
1298917000518	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1298917000519	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1298917000520	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1298917000521	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1298917000522	ATP binding site [chemical binding]; other site
1298917000523	putative Mg++ binding site [ion binding]; other site
1298917000524	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917000525	nucleotide binding region [chemical binding]; other site
1298917000526	ATP-binding site [chemical binding]; other site
1298917000527	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1298917000528	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1298917000529	Transglycosylase; Region: Transgly; pfam00912
1298917000530	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1298917000531	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1298917000532	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1298917000533	Walker A/P-loop; other site
1298917000534	ATP binding site [chemical binding]; other site
1298917000535	Q-loop/lid; other site
1298917000536	ABC transporter signature motif; other site
1298917000537	Walker B; other site
1298917000538	D-loop; other site
1298917000539	H-loop/switch region; other site
1298917000540	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
1298917000541	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917000542	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917000543	putative minor fimbrial subunit StfE; Provisional; Region: PRK15286
1298917000544	putative minor fimbrial subunit StfG; Provisional; Region: PRK15288
1298917000545	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
1298917000546	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1298917000547	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1298917000548	inhibitor-cofactor binding pocket; inhibition site
1298917000549	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917000550	catalytic residue [active]
1298917000551	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1298917000552	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1298917000553	Cl- selectivity filter; other site
1298917000554	Cl- binding residues [ion binding]; other site
1298917000555	pore gating glutamate residue; other site
1298917000556	dimer interface [polypeptide binding]; other site
1298917000557	H+/Cl- coupling transport residue; other site
1298917000558	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1298917000559	hypothetical protein; Provisional; Region: PRK10578
1298917000560	UPF0126 domain; Region: UPF0126; pfam03458
1298917000561	UPF0126 domain; Region: UPF0126; pfam03458
1298917000562	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1298917000563	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1298917000564	cobalamin binding residues [chemical binding]; other site
1298917000565	putative BtuC binding residues; other site
1298917000566	dimer interface [polypeptide binding]; other site
1298917000567	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1298917000568	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1298917000569	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1298917000570	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1298917000571	Zn2+ binding site [ion binding]; other site
1298917000572	Mg2+ binding site [ion binding]; other site
1298917000573	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1298917000574	serine endoprotease; Provisional; Region: PRK10942
1298917000575	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1298917000576	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1298917000577	protein binding site [polypeptide binding]; other site
1298917000578	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1298917000579	hypothetical protein; Provisional; Region: PRK13677
1298917000580	shikimate transporter; Provisional; Region: PRK09952
1298917000581	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917000582	putative substrate translocation pore; other site
1298917000583	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1298917000584	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1298917000585	trimer interface [polypeptide binding]; other site
1298917000586	active site
1298917000587	substrate binding site [chemical binding]; other site
1298917000588	CoA binding site [chemical binding]; other site
1298917000589	PII uridylyl-transferase; Provisional; Region: PRK05007
1298917000590	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1298917000591	metal binding triad; other site
1298917000592	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1298917000593	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1298917000594	Zn2+ binding site [ion binding]; other site
1298917000595	Mg2+ binding site [ion binding]; other site
1298917000596	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1298917000597	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1298917000598	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1298917000599	active site
1298917000600	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1298917000601	rRNA interaction site [nucleotide binding]; other site
1298917000602	S8 interaction site; other site
1298917000603	putative laminin-1 binding site; other site
1298917000604	elongation factor Ts; Provisional; Region: tsf; PRK09377
1298917000605	UBA/TS-N domain; Region: UBA; pfam00627
1298917000606	Elongation factor TS; Region: EF_TS; pfam00889
1298917000607	Elongation factor TS; Region: EF_TS; pfam00889
1298917000608	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1298917000609	putative nucleotide binding site [chemical binding]; other site
1298917000610	uridine monophosphate binding site [chemical binding]; other site
1298917000611	homohexameric interface [polypeptide binding]; other site
1298917000612	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1298917000613	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1298917000614	hinge region; other site
1298917000615	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1298917000616	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1298917000617	catalytic residue [active]
1298917000618	putative FPP diphosphate  binding site; other site
1298917000619	putative FPP binding hydrophobic cleft; other site
1298917000620	dimer interface [polypeptide binding]; other site
1298917000621	putative IPP diphosphate binding site; other site
1298917000622	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1298917000623	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1298917000624	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1298917000625	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1298917000626	active site
1298917000627	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1298917000628	protein binding site [polypeptide binding]; other site
1298917000629	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1298917000630	protein binding site [polypeptide binding]; other site
1298917000631	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1298917000632	putative substrate binding region [chemical binding]; other site
1298917000633	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1298917000634	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1298917000635	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1298917000636	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1298917000637	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1298917000638	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1298917000639	Surface antigen; Region: Bac_surface_Ag; pfam01103
1298917000640	periplasmic chaperone; Provisional; Region: PRK10780
1298917000641	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1298917000642	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1298917000643	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1298917000644	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1298917000645	trimer interface [polypeptide binding]; other site
1298917000646	active site
1298917000647	UDP-GlcNAc binding site [chemical binding]; other site
1298917000648	lipid binding site [chemical binding]; lipid-binding site
1298917000649	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1298917000650	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1298917000651	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1298917000652	active site
1298917000653	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1298917000654	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1298917000655	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1298917000656	RNA/DNA hybrid binding site [nucleotide binding]; other site
1298917000657	active site
1298917000658	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1298917000659	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1298917000660	putative active site [active]
1298917000661	putative PHP Thumb interface [polypeptide binding]; other site
1298917000662	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1298917000663	generic binding surface II; other site
1298917000664	generic binding surface I; other site
1298917000665	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1298917000666	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1298917000667	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1298917000668	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
1298917000669	putative sugar binding site [chemical binding]; other site
1298917000670	catalytic residues [active]
1298917000671	PKD domain; Region: PKD; pfam00801
1298917000672	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1298917000673	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1298917000674	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1298917000675	homodimer interface [polypeptide binding]; other site
1298917000676	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917000677	catalytic residue [active]
1298917000678	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1298917000679	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1298917000680	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1298917000681	putative metal binding site [ion binding]; other site
1298917000682	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1298917000683	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1298917000684	Ligand Binding Site [chemical binding]; other site
1298917000685	TilS substrate binding domain; Region: TilS; pfam09179
1298917000686	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1298917000687	Rho-binding antiterminator; Provisional; Region: PRK11625
1298917000688	hypothetical protein; Provisional; Region: PRK04964
1298917000689	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1298917000690	hypothetical protein; Provisional; Region: PRK09256
1298917000691	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1298917000692	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1298917000693	NlpE N-terminal domain; Region: NlpE; pfam04170
1298917000694	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1298917000695	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1298917000696	dimer interface [polypeptide binding]; other site
1298917000697	motif 1; other site
1298917000698	active site
1298917000699	motif 2; other site
1298917000700	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1298917000701	putative deacylase active site [active]
1298917000702	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1298917000703	active site
1298917000704	motif 3; other site
1298917000705	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1298917000706	anticodon binding site; other site
1298917000707	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1298917000708	homodimer interaction site [polypeptide binding]; other site
1298917000709	cofactor binding site; other site
1298917000710	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1298917000711	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1298917000712	lipoprotein, YaeC family; Region: TIGR00363
1298917000713	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917000714	dimer interface [polypeptide binding]; other site
1298917000715	conserved gate region; other site
1298917000716	ABC-ATPase subunit interface; other site
1298917000717	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1298917000718	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1298917000719	Walker A/P-loop; other site
1298917000720	ATP binding site [chemical binding]; other site
1298917000721	Q-loop/lid; other site
1298917000722	ABC transporter signature motif; other site
1298917000723	Walker B; other site
1298917000724	D-loop; other site
1298917000725	H-loop/switch region; other site
1298917000726	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1298917000727	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1298917000728	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917000729	active site
1298917000730	motif I; other site
1298917000731	motif II; other site
1298917000732	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1298917000733	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1298917000734	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917000735	putative substrate translocation pore; other site
1298917000736	lipoprotein; Provisional; Region: PRK10759
1298917000737	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1298917000738	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1298917000739	domain interface [polypeptide binding]; other site
1298917000740	putative active site [active]
1298917000741	catalytic site [active]
1298917000742	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1298917000743	domain interface [polypeptide binding]; other site
1298917000744	putative active site [active]
1298917000745	catalytic site [active]
1298917000746	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1298917000747	CoA binding domain; Region: CoA_binding_2; pfam13380
1298917000748	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1298917000749	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1298917000750	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1298917000751	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917000752	Coenzyme A binding pocket [chemical binding]; other site
1298917000753	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1298917000754	putative methyltransferase; Provisional; Region: PRK10864
1298917000755	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1298917000756	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1298917000757	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1298917000758	ligand binding site [chemical binding]; other site
1298917000759	active site
1298917000760	UGI interface [polypeptide binding]; other site
1298917000761	catalytic site [active]
1298917000762	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1298917000763	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917000764	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917000765	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1298917000766	dimerization interface [polypeptide binding]; other site
1298917000767	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1298917000768	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1298917000769	ATP binding site [chemical binding]; other site
1298917000770	Mg++ binding site [ion binding]; other site
1298917000771	motif III; other site
1298917000772	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917000773	nucleotide binding region [chemical binding]; other site
1298917000774	ATP-binding site [chemical binding]; other site
1298917000775	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1298917000776	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917000777	S-adenosylmethionine binding site [chemical binding]; other site
1298917000778	L-aspartate oxidase; Provisional; Region: PRK09077
1298917000779	L-aspartate oxidase; Provisional; Region: PRK06175
1298917000780	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1298917000781	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1298917000782	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1298917000783	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1298917000784	DNA binding residues [nucleotide binding]
1298917000785	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1298917000786	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1298917000787	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1298917000788	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1298917000789	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1298917000790	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1298917000791	GTP-binding protein LepA; Provisional; Region: PRK05433
1298917000792	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1298917000793	G1 box; other site
1298917000794	putative GEF interaction site [polypeptide binding]; other site
1298917000795	GTP/Mg2+ binding site [chemical binding]; other site
1298917000796	Switch I region; other site
1298917000797	G2 box; other site
1298917000798	G3 box; other site
1298917000799	Switch II region; other site
1298917000800	G4 box; other site
1298917000801	G5 box; other site
1298917000802	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1298917000803	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1298917000804	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1298917000805	signal peptidase I; Provisional; Region: PRK10861
1298917000806	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1298917000807	Catalytic site [active]
1298917000808	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1298917000809	ribonuclease III; Reviewed; Region: rnc; PRK00102
1298917000810	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1298917000811	dimerization interface [polypeptide binding]; other site
1298917000812	active site
1298917000813	metal binding site [ion binding]; metal-binding site
1298917000814	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1298917000815	dsRNA binding site [nucleotide binding]; other site
1298917000816	GTPase Era; Reviewed; Region: era; PRK00089
1298917000817	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1298917000818	G1 box; other site
1298917000819	GTP/Mg2+ binding site [chemical binding]; other site
1298917000820	Switch I region; other site
1298917000821	G2 box; other site
1298917000822	Switch II region; other site
1298917000823	G3 box; other site
1298917000824	G4 box; other site
1298917000825	G5 box; other site
1298917000826	KH domain; Region: KH_2; pfam07650
1298917000827	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1298917000828	Recombination protein O N terminal; Region: RecO_N; pfam11967
1298917000829	Recombination protein O C terminal; Region: RecO_C; pfam02565
1298917000830	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1298917000831	active site
1298917000832	hydrophilic channel; other site
1298917000833	dimerization interface [polypeptide binding]; other site
1298917000834	catalytic residues [active]
1298917000835	active site lid [active]
1298917000836	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1298917000837	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1298917000838	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917000839	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917000840	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1298917000841	dimerization interface [polypeptide binding]; other site
1298917000842	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1298917000843	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917000844	putative substrate translocation pore; other site
1298917000845	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1298917000846	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1298917000847	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1298917000848	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1298917000849	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1298917000850	putative active site [active]
1298917000851	hypothetical protein; Provisional; Region: PRK11590
1298917000852	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1298917000853	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1298917000854	nucleoside/Zn binding site; other site
1298917000855	dimer interface [polypeptide binding]; other site
1298917000856	catalytic motif [active]
1298917000857	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1298917000858	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917000859	substrate binding pocket [chemical binding]; other site
1298917000860	membrane-bound complex binding site; other site
1298917000861	hinge residues; other site
1298917000862	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1298917000863	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1298917000864	catalytic residue [active]
1298917000865	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1298917000866	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1298917000867	dimerization interface [polypeptide binding]; other site
1298917000868	ATP binding site [chemical binding]; other site
1298917000869	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
1298917000870	dimerization interface [polypeptide binding]; other site
1298917000871	ATP binding site [chemical binding]; other site
1298917000872	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1298917000873	putative active site [active]
1298917000874	catalytic triad [active]
1298917000875	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1298917000876	HAMP domain; Region: HAMP; pfam00672
1298917000877	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917000878	dimer interface [polypeptide binding]; other site
1298917000879	phosphorylation site [posttranslational modification]
1298917000880	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917000881	ATP binding site [chemical binding]; other site
1298917000882	Mg2+ binding site [ion binding]; other site
1298917000883	G-X-G motif; other site
1298917000884	hypothetical protein; Provisional; Region: PRK10722
1298917000885	response regulator GlrR; Provisional; Region: PRK15115
1298917000886	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917000887	active site
1298917000888	phosphorylation site [posttranslational modification]
1298917000889	intermolecular recognition site; other site
1298917000890	dimerization interface [polypeptide binding]; other site
1298917000891	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917000892	Walker A motif; other site
1298917000893	ATP binding site [chemical binding]; other site
1298917000894	Walker B motif; other site
1298917000895	arginine finger; other site
1298917000896	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1298917000897	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1298917000898	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1298917000899	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917000900	putative substrate translocation pore; other site
1298917000901	POT family; Region: PTR2; pfam00854
1298917000902	lysine decarboxylase CadA; Provisional; Region: PRK15400
1298917000903	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1298917000904	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1298917000905	homodimer interface [polypeptide binding]; other site
1298917000906	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917000907	catalytic residue [active]
1298917000908	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1298917000909	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
1298917000910	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
1298917000911	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917000912	DNA binding site [nucleotide binding]
1298917000913	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1298917000914	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1298917000915	heme-binding site [chemical binding]; other site
1298917000916	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1298917000917	FAD binding pocket [chemical binding]; other site
1298917000918	FAD binding motif [chemical binding]; other site
1298917000919	phosphate binding motif [ion binding]; other site
1298917000920	beta-alpha-beta structure motif; other site
1298917000921	NAD binding pocket [chemical binding]; other site
1298917000922	Heme binding  pocket [chemical binding]; other site
1298917000923	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1298917000924	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1298917000925	dimer interface [polypeptide binding]; other site
1298917000926	active site
1298917000927	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1298917000928	folate binding site [chemical binding]; other site
1298917000929	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1298917000930	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917000931	putative substrate translocation pore; other site
1298917000932	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1298917000933	PRD domain; Region: PRD; pfam00874
1298917000934	PRD domain; Region: PRD; pfam00874
1298917000935	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
1298917000936	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1298917000937	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
1298917000938	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1298917000939	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1298917000940	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1298917000941	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1298917000942	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1298917000943	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1298917000944	active site
1298917000945	dimerization interface [polypeptide binding]; other site
1298917000946	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1298917000947	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1298917000948	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1298917000949	Rrf2 family protein; Region: rrf2_super; TIGR00738
1298917000950	cysteine desulfurase; Provisional; Region: PRK14012
1298917000951	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1298917000952	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1298917000953	catalytic residue [active]
1298917000954	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1298917000955	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1298917000956	trimerization site [polypeptide binding]; other site
1298917000957	active site
1298917000958	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1298917000959	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1298917000960	DnaJ domain; Region: DnaJ; pfam00226
1298917000961	HSP70 interaction site [polypeptide binding]; other site
1298917000962	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1298917000963	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1298917000964	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1298917000965	nucleotide binding site [chemical binding]; other site
1298917000966	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1298917000967	SBD interface [polypeptide binding]; other site
1298917000968	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1298917000969	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1298917000970	catalytic loop [active]
1298917000971	iron binding site [ion binding]; other site
1298917000972	hypothetical protein; Provisional; Region: PRK10721
1298917000973	aminopeptidase B; Provisional; Region: PRK05015
1298917000974	Peptidase; Region: DUF3663; pfam12404
1298917000975	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1298917000976	interface (dimer of trimers) [polypeptide binding]; other site
1298917000977	Substrate-binding/catalytic site; other site
1298917000978	Zn-binding sites [ion binding]; other site
1298917000979	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1298917000980	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1298917000981	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1298917000982	active site residue [active]
1298917000983	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1298917000984	active site residue [active]
1298917000985	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1298917000986	MG2 domain; Region: A2M_N; pfam01835
1298917000987	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1298917000988	surface patch; other site
1298917000989	thioester region; other site
1298917000990	specificity defining residues; other site
1298917000991	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
1298917000992	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1298917000993	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1298917000994	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1298917000995	putative [Fe4-S4] binding site [ion binding]; other site
1298917000996	putative molybdopterin cofactor binding site [chemical binding]; other site
1298917000997	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1298917000998	putative molybdopterin cofactor binding site; other site
1298917000999	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1298917001000	4Fe-4S binding domain; Region: Fer4; pfam00037
1298917001001	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1298917001002	4Fe-4S binding domain; Region: Fer4; pfam00037
1298917001003	hydrogenase 4 subunit H; Validated; Region: PRK08222
1298917001004	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1298917001005	active site
1298917001006	multimer interface [polypeptide binding]; other site
1298917001007	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1298917001008	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917001009	FeS/SAM binding site; other site
1298917001010	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1298917001011	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917001012	non-specific DNA binding site [nucleotide binding]; other site
1298917001013	salt bridge; other site
1298917001014	sequence-specific DNA binding site [nucleotide binding]; other site
1298917001015	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1298917001016	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1298917001017	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1298917001018	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1298917001019	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1298917001020	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1298917001021	dimer interface [polypeptide binding]; other site
1298917001022	motif 1; other site
1298917001023	active site
1298917001024	motif 2; other site
1298917001025	motif 3; other site
1298917001026	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1298917001027	anticodon binding site; other site
1298917001028	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1298917001029	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1298917001030	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1298917001031	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1298917001032	Trp docking motif [polypeptide binding]; other site
1298917001033	GTP-binding protein Der; Reviewed; Region: PRK00093
1298917001034	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1298917001035	G1 box; other site
1298917001036	GTP/Mg2+ binding site [chemical binding]; other site
1298917001037	Switch I region; other site
1298917001038	G2 box; other site
1298917001039	Switch II region; other site
1298917001040	G3 box; other site
1298917001041	G4 box; other site
1298917001042	G5 box; other site
1298917001043	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1298917001044	G1 box; other site
1298917001045	GTP/Mg2+ binding site [chemical binding]; other site
1298917001046	Switch I region; other site
1298917001047	G2 box; other site
1298917001048	G3 box; other site
1298917001049	Switch II region; other site
1298917001050	G4 box; other site
1298917001051	G5 box; other site
1298917001052	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1298917001053	intimin-like protein SinH; Provisional; Region: PRK15318
1298917001054	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1298917001055	intimin-like protein SinH; Provisional; Region: PRK15318
1298917001056	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1298917001057	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1298917001058	generic binding surface II; other site
1298917001059	generic binding surface I; other site
1298917001060	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1298917001061	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1298917001062	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1298917001063	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1298917001064	active site
1298917001065	GMP synthase; Reviewed; Region: guaA; PRK00074
1298917001066	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1298917001067	AMP/PPi binding site [chemical binding]; other site
1298917001068	candidate oxyanion hole; other site
1298917001069	catalytic triad [active]
1298917001070	potential glutamine specificity residues [chemical binding]; other site
1298917001071	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1298917001072	ATP Binding subdomain [chemical binding]; other site
1298917001073	Ligand Binding sites [chemical binding]; other site
1298917001074	Dimerization subdomain; other site
1298917001075	Integrase core domain; Region: rve; pfam00665
1298917001076	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1298917001077	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1298917001078	exopolyphosphatase; Provisional; Region: PRK10854
1298917001079	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1298917001080	nucleotide binding site [chemical binding]; other site
1298917001081	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1298917001082	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1298917001083	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1298917001084	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1298917001085	putative active site [active]
1298917001086	catalytic site [active]
1298917001087	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1298917001088	domain interface [polypeptide binding]; other site
1298917001089	active site
1298917001090	catalytic site [active]
1298917001091	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1298917001092	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1298917001093	active site
1298917001094	substrate binding site [chemical binding]; other site
1298917001095	cosubstrate binding site; other site
1298917001096	catalytic site [active]
1298917001097	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1298917001098	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1298917001099	dimerization interface [polypeptide binding]; other site
1298917001100	putative ATP binding site [chemical binding]; other site
1298917001101	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1298917001102	active site
1298917001103	uracil transporter; Provisional; Region: PRK10720
1298917001104	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1298917001105	DNA replication initiation factor; Provisional; Region: PRK08084
1298917001106	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1298917001107	ArsC family; Region: ArsC; pfam03960
1298917001108	catalytic residues [active]
1298917001109	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1298917001110	Peptidase family M48; Region: Peptidase_M48; cl12018
1298917001111	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
1298917001112	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1298917001113	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1298917001114	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1298917001115	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1298917001116	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1298917001117	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1298917001118	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1298917001119	catalytic triad [active]
1298917001120	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1298917001121	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1298917001122	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1298917001123	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1298917001124	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1298917001125	dimer interface [polypeptide binding]; other site
1298917001126	active site
1298917001127	catalytic residue [active]
1298917001128	lipoprotein; Provisional; Region: PRK11679
1298917001129	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1298917001130	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1298917001131	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1298917001132	ATP binding site [chemical binding]; other site
1298917001133	active site
1298917001134	substrate binding site [chemical binding]; other site
1298917001135	Predicted metalloprotease [General function prediction only]; Region: COG2321
1298917001136	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1298917001137	hypothetical protein; Provisional; Region: PRK13664
1298917001138	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1298917001139	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1298917001140	metal binding site [ion binding]; metal-binding site
1298917001141	dimer interface [polypeptide binding]; other site
1298917001142	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1298917001143	ArsC family; Region: ArsC; pfam03960
1298917001144	putative catalytic residues [active]
1298917001145	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1298917001146	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1298917001147	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917001148	dimerization interface [polypeptide binding]; other site
1298917001149	Histidine kinase; Region: HisKA_3; pfam07730
1298917001150	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917001151	ATP binding site [chemical binding]; other site
1298917001152	Mg2+ binding site [ion binding]; other site
1298917001153	G-X-G motif; other site
1298917001154	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1298917001155	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1298917001156	dimer interface [polypeptide binding]; other site
1298917001157	ADP-ribose binding site [chemical binding]; other site
1298917001158	active site
1298917001159	nudix motif; other site
1298917001160	metal binding site [ion binding]; metal-binding site
1298917001161	transketolase; Reviewed; Region: PRK12753
1298917001162	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1298917001163	TPP-binding site [chemical binding]; other site
1298917001164	dimer interface [polypeptide binding]; other site
1298917001165	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1298917001166	PYR/PP interface [polypeptide binding]; other site
1298917001167	dimer interface [polypeptide binding]; other site
1298917001168	TPP binding site [chemical binding]; other site
1298917001169	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1298917001170	transaldolase-like protein; Provisional; Region: PTZ00411
1298917001171	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1298917001172	active site
1298917001173	dimer interface [polypeptide binding]; other site
1298917001174	catalytic residue [active]
1298917001175	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1298917001176	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1298917001177	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1298917001178	putative NAD(P) binding site [chemical binding]; other site
1298917001179	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1298917001180	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1298917001181	putative hexamer interface [polypeptide binding]; other site
1298917001182	putative hexagonal pore; other site
1298917001183	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1298917001184	G1 box; other site
1298917001185	GTP/Mg2+ binding site [chemical binding]; other site
1298917001186	G2 box; other site
1298917001187	Switch I region; other site
1298917001188	G3 box; other site
1298917001189	Switch II region; other site
1298917001190	G4 box; other site
1298917001191	G5 box; other site
1298917001192	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1298917001193	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
1298917001194	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
1298917001195	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1298917001196	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
1298917001197	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1298917001198	nucleotide binding site [chemical binding]; other site
1298917001199	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
1298917001200	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1298917001201	active site
1298917001202	metal binding site [ion binding]; metal-binding site
1298917001203	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
1298917001204	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1298917001205	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1298917001206	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1298917001207	carboxysome structural protein EutK; Provisional; Region: PRK15466
1298917001208	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1298917001209	Hexamer interface [polypeptide binding]; other site
1298917001210	Hexagonal pore residue; other site
1298917001211	transcriptional regulator EutR; Provisional; Region: PRK10130
1298917001212	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917001213	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917001214	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1298917001215	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1298917001216	active site
1298917001217	metal binding site [ion binding]; metal-binding site
1298917001218	putative acetyltransferase; Provisional; Region: PRK03624
1298917001219	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917001220	Coenzyme A binding pocket [chemical binding]; other site
1298917001221	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1298917001222	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1298917001223	short chain dehydrogenase; Provisional; Region: PRK08226
1298917001224	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
1298917001225	NAD binding site [chemical binding]; other site
1298917001226	homotetramer interface [polypeptide binding]; other site
1298917001227	homodimer interface [polypeptide binding]; other site
1298917001228	active site
1298917001229	thiosulfate transporter subunit; Provisional; Region: PRK10852
1298917001230	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1298917001231	sulfate transport protein; Provisional; Region: cysT; CHL00187
1298917001232	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917001233	dimer interface [polypeptide binding]; other site
1298917001234	conserved gate region; other site
1298917001235	putative PBP binding loops; other site
1298917001236	ABC-ATPase subunit interface; other site
1298917001237	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1298917001238	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1298917001239	Walker A/P-loop; other site
1298917001240	ATP binding site [chemical binding]; other site
1298917001241	Q-loop/lid; other site
1298917001242	ABC transporter signature motif; other site
1298917001243	Walker B; other site
1298917001244	D-loop; other site
1298917001245	H-loop/switch region; other site
1298917001246	TOBE-like domain; Region: TOBE_3; pfam12857
1298917001247	cysteine synthase B; Region: cysM; TIGR01138
1298917001248	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1298917001249	dimer interface [polypeptide binding]; other site
1298917001250	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917001251	catalytic residue [active]
1298917001252	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1298917001253	Sel1-like repeats; Region: SEL1; smart00671
1298917001254	hypothetical protein; Provisional; Region: PRK10318
1298917001255	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1298917001256	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1298917001257	catalytic triad [active]
1298917001258	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
1298917001259	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917001260	DNA-binding site [nucleotide binding]; DNA binding site
1298917001261	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917001262	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917001263	homodimer interface [polypeptide binding]; other site
1298917001264	catalytic residue [active]
1298917001265	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1298917001266	dimer interface [polypeptide binding]; other site
1298917001267	pyridoxamine kinase; Validated; Region: PRK05756
1298917001268	pyridoxal binding site [chemical binding]; other site
1298917001269	ATP binding site [chemical binding]; other site
1298917001270	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1298917001271	HPr interaction site; other site
1298917001272	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1298917001273	active site
1298917001274	phosphorylation site [posttranslational modification]
1298917001275	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1298917001276	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1298917001277	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1298917001278	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1298917001279	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1298917001280	dimerization domain swap beta strand [polypeptide binding]; other site
1298917001281	regulatory protein interface [polypeptide binding]; other site
1298917001282	active site
1298917001283	regulatory phosphorylation site [posttranslational modification]; other site
1298917001284	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1298917001285	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1298917001286	dimer interface [polypeptide binding]; other site
1298917001287	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917001288	catalytic residue [active]
1298917001289	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1298917001290	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1298917001291	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1298917001292	nucleotide binding pocket [chemical binding]; other site
1298917001293	K-X-D-G motif; other site
1298917001294	catalytic site [active]
1298917001295	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1298917001296	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1298917001297	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; cl17855
1298917001298	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1298917001299	Dimer interface [polypeptide binding]; other site
1298917001300	BRCT sequence motif; other site
1298917001301	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1298917001302	hypothetical protein; Provisional; Region: PRK11528
1298917001303	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1298917001304	nucleoside transporter; Region: 2A0110; TIGR00889
1298917001305	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001306	putative substrate translocation pore; other site
1298917001307	XapX domain; Region: XapX; TIGR03510
1298917001308	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1298917001309	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917001310	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
1298917001311	putative dimerization interface [polypeptide binding]; other site
1298917001312	putative substrate binding pocket [chemical binding]; other site
1298917001313	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1298917001314	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1298917001315	active site
1298917001316	HIGH motif; other site
1298917001317	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1298917001318	active site
1298917001319	KMSKS motif; other site
1298917001320	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1298917001321	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1298917001322	MASE1; Region: MASE1; pfam05231
1298917001323	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1298917001324	diguanylate cyclase; Region: GGDEF; smart00267
1298917001325	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917001326	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1298917001327	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1298917001328	Nucleoside recognition; Region: Gate; pfam07670
1298917001329	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1298917001330	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1298917001331	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1298917001332	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1298917001333	Cl- selectivity filter; other site
1298917001334	Cl- binding residues [ion binding]; other site
1298917001335	pore gating glutamate residue; other site
1298917001336	dimer interface [polypeptide binding]; other site
1298917001337	glucokinase; Provisional; Region: glk; PRK00292
1298917001338	glucokinase, proteobacterial type; Region: glk; TIGR00749
1298917001339	aminotransferase; Validated; Region: PRK08175
1298917001340	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917001341	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917001342	homodimer interface [polypeptide binding]; other site
1298917001343	catalytic residue [active]
1298917001344	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1298917001345	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1298917001346	putative acyl-acceptor binding pocket; other site
1298917001347	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
1298917001348	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1298917001349	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001350	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001351	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1298917001352	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1298917001353	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
1298917001354	HAMP domain; Region: HAMP; pfam00672
1298917001355	dimerization interface [polypeptide binding]; other site
1298917001356	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1298917001357	dimer interface [polypeptide binding]; other site
1298917001358	phosphorylation site [posttranslational modification]
1298917001359	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917001360	ATP binding site [chemical binding]; other site
1298917001361	Mg2+ binding site [ion binding]; other site
1298917001362	G-X-G motif; other site
1298917001363	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1298917001364	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917001365	active site
1298917001366	phosphorylation site [posttranslational modification]
1298917001367	intermolecular recognition site; other site
1298917001368	dimerization interface [polypeptide binding]; other site
1298917001369	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1298917001370	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1298917001371	outer membrane protease; Reviewed; Region: PRK10993
1298917001372	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1298917001373	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1298917001374	active site
1298917001375	Predicted membrane protein [Function unknown]; Region: COG2246
1298917001376	GtrA-like protein; Region: GtrA; pfam04138
1298917001377	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1298917001378	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1298917001379	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1298917001380	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1298917001381	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1298917001382	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1298917001383	dimer interface [polypeptide binding]; other site
1298917001384	active site
1298917001385	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1298917001386	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1298917001387	substrate binding site [chemical binding]; other site
1298917001388	oxyanion hole (OAH) forming residues; other site
1298917001389	trimer interface [polypeptide binding]; other site
1298917001390	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1298917001391	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1298917001392	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1298917001393	catalytic core [active]
1298917001394	hypothetical protein; Provisional; Region: PRK04946
1298917001395	Smr domain; Region: Smr; pfam01713
1298917001396	HemK family putative methylases; Region: hemK_fam; TIGR00536
1298917001397	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917001398	S-adenosylmethionine binding site [chemical binding]; other site
1298917001399	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1298917001400	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1298917001401	Tetramer interface [polypeptide binding]; other site
1298917001402	active site
1298917001403	FMN-binding site [chemical binding]; other site
1298917001404	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1298917001405	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1298917001406	hypothetical protein; Provisional; Region: PRK10621
1298917001407	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1298917001408	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
1298917001409	YfcL protein; Region: YfcL; pfam08891
1298917001410	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1298917001411	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1298917001412	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1298917001413	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1298917001414	dimer interface [polypeptide binding]; other site
1298917001415	active site
1298917001416	CAAX protease self-immunity; Region: Abi; pfam02517
1298917001417	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1298917001418	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917001419	non-specific DNA binding site [nucleotide binding]; other site
1298917001420	salt bridge; other site
1298917001421	sequence-specific DNA binding site [nucleotide binding]; other site
1298917001422	putative transporter; Provisional; Region: PRK12382
1298917001423	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001424	putative substrate translocation pore; other site
1298917001425	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1298917001426	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1298917001427	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1298917001428	ligand binding site [chemical binding]; other site
1298917001429	NAD binding site [chemical binding]; other site
1298917001430	catalytic site [active]
1298917001431	homodimer interface [polypeptide binding]; other site
1298917001432	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1298917001433	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1298917001434	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
1298917001435	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1298917001436	dimerization interface 3.5A [polypeptide binding]; other site
1298917001437	active site
1298917001438	hypothetical protein; Provisional; Region: PRK10847
1298917001439	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1298917001440	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1298917001441	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1298917001442	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1298917001443	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1298917001444	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1298917001445	cell division protein DedD; Provisional; Region: PRK11633
1298917001446	Sporulation related domain; Region: SPOR; pfam05036
1298917001447	colicin V production protein; Provisional; Region: PRK10845
1298917001448	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1298917001449	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1298917001450	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1298917001451	active site
1298917001452	tetramer interface [polypeptide binding]; other site
1298917001453	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1298917001454	active site
1298917001455	PAS fold; Region: PAS_4; pfam08448
1298917001456	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1298917001457	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917001458	Walker A motif; other site
1298917001459	ATP binding site [chemical binding]; other site
1298917001460	Walker B motif; other site
1298917001461	arginine finger; other site
1298917001462	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1298917001463	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1298917001464	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1298917001465	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1298917001466	catalytic residue [active]
1298917001467	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
1298917001468	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
1298917001469	dimer interface [polypeptide binding]; other site
1298917001470	active site
1298917001471	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1298917001472	substrate binding site [chemical binding]; other site
1298917001473	catalytic residue [active]
1298917001474	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1298917001475	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1298917001476	Flavoprotein; Region: Flavoprotein; pfam02441
1298917001477	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1298917001478	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917001479	substrate binding pocket [chemical binding]; other site
1298917001480	membrane-bound complex binding site; other site
1298917001481	hinge residues; other site
1298917001482	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1298917001483	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917001484	dimer interface [polypeptide binding]; other site
1298917001485	conserved gate region; other site
1298917001486	putative PBP binding loops; other site
1298917001487	ABC-ATPase subunit interface; other site
1298917001488	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1298917001489	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917001490	dimer interface [polypeptide binding]; other site
1298917001491	conserved gate region; other site
1298917001492	putative PBP binding loops; other site
1298917001493	ABC-ATPase subunit interface; other site
1298917001494	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1298917001495	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1298917001496	Walker A/P-loop; other site
1298917001497	ATP binding site [chemical binding]; other site
1298917001498	Q-loop/lid; other site
1298917001499	ABC transporter signature motif; other site
1298917001500	Walker B; other site
1298917001501	D-loop; other site
1298917001502	H-loop/switch region; other site
1298917001503	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1298917001504	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1298917001505	putative NAD(P) binding site [chemical binding]; other site
1298917001506	putative active site [active]
1298917001507	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1298917001508	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1298917001509	C-terminal domain interface [polypeptide binding]; other site
1298917001510	GSH binding site (G-site) [chemical binding]; other site
1298917001511	dimer interface [polypeptide binding]; other site
1298917001512	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1298917001513	N-terminal domain interface [polypeptide binding]; other site
1298917001514	putative dimer interface [polypeptide binding]; other site
1298917001515	active site
1298917001516	glutathione S-transferase; Provisional; Region: PRK15113
1298917001517	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1298917001518	C-terminal domain interface [polypeptide binding]; other site
1298917001519	GSH binding site (G-site) [chemical binding]; other site
1298917001520	dimer interface [polypeptide binding]; other site
1298917001521	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1298917001522	N-terminal domain interface [polypeptide binding]; other site
1298917001523	putative dimer interface [polypeptide binding]; other site
1298917001524	putative substrate binding pocket (H-site) [chemical binding]; other site
1298917001525	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1298917001526	active site
1298917001527	metal binding site [ion binding]; metal-binding site
1298917001528	homotetramer interface [polypeptide binding]; other site
1298917001529	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1298917001530	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1298917001531	nudix motif; other site
1298917001532	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1298917001533	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917001534	DNA binding site [nucleotide binding]
1298917001535	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1298917001536	putative dimerization interface [polypeptide binding]; other site
1298917001537	putative ligand binding site [chemical binding]; other site
1298917001538	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1298917001539	active site
1298917001540	phosphorylation site [posttranslational modification]
1298917001541	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1298917001542	active site
1298917001543	P-loop; other site
1298917001544	phosphorylation site [posttranslational modification]
1298917001545	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
1298917001546	transketolase; Reviewed; Region: PRK05899
1298917001547	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1298917001548	TPP-binding site [chemical binding]; other site
1298917001549	dimer interface [polypeptide binding]; other site
1298917001550	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1298917001551	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1298917001552	PYR/PP interface [polypeptide binding]; other site
1298917001553	dimer interface [polypeptide binding]; other site
1298917001554	TPP binding site [chemical binding]; other site
1298917001555	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1298917001556	hypothetical protein; Provisional; Region: PRK11588
1298917001557	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1298917001558	phosphate acetyltransferase; Reviewed; Region: PRK05632
1298917001559	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1298917001560	DRTGG domain; Region: DRTGG; pfam07085
1298917001561	phosphate acetyltransferase; Region: pta; TIGR00651
1298917001562	propionate/acetate kinase; Provisional; Region: PRK12379
1298917001563	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1298917001564	hypothetical protein; Provisional; Region: PRK01816
1298917001565	hypothetical protein; Validated; Region: PRK05445
1298917001566	putative phosphatase; Provisional; Region: PRK11587
1298917001567	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917001568	motif II; other site
1298917001569	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1298917001570	transmembrane helices; other site
1298917001571	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1298917001572	TrkA-C domain; Region: TrkA_C; pfam02080
1298917001573	TrkA-C domain; Region: TrkA_C; pfam02080
1298917001574	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1298917001575	5'-nucleotidase; Provisional; Region: PRK03826
1298917001576	aminotransferase AlaT; Validated; Region: PRK09265
1298917001577	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917001578	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917001579	homodimer interface [polypeptide binding]; other site
1298917001580	catalytic residue [active]
1298917001581	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1298917001582	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917001583	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1298917001584	putative dimerization interface [polypeptide binding]; other site
1298917001585	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1298917001586	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1298917001587	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1298917001588	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1298917001589	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1298917001590	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1298917001591	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1298917001592	putative dimer interface [polypeptide binding]; other site
1298917001593	[2Fe-2S] cluster binding site [ion binding]; other site
1298917001594	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1298917001595	SLBB domain; Region: SLBB; pfam10531
1298917001596	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1298917001597	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1298917001598	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1298917001599	catalytic loop [active]
1298917001600	iron binding site [ion binding]; other site
1298917001601	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1298917001602	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1298917001603	[4Fe-4S] binding site [ion binding]; other site
1298917001604	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1298917001605	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1298917001606	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1298917001607	4Fe-4S binding domain; Region: Fer4; pfam00037
1298917001608	4Fe-4S binding domain; Region: Fer4; pfam00037
1298917001609	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1298917001610	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1298917001611	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1298917001612	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1298917001613	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1298917001614	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1298917001615	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1298917001616	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1298917001617	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1298917001618	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1298917001619	von Willebrand factor; Region: vWF_A; pfam12450
1298917001620	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
1298917001621	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
1298917001622	metal ion-dependent adhesion site (MIDAS); other site
1298917001623	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
1298917001624	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1298917001625	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1298917001626	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917001627	active site
1298917001628	phosphorylation site [posttranslational modification]
1298917001629	intermolecular recognition site; other site
1298917001630	dimerization interface [polypeptide binding]; other site
1298917001631	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1298917001632	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917001633	Coenzyme A binding pocket [chemical binding]; other site
1298917001634	hypothetical protein; Provisional; Region: PRK10404
1298917001635	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1298917001636	isochorismate synthases; Region: isochor_syn; TIGR00543
1298917001637	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1298917001638	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1298917001639	dimer interface [polypeptide binding]; other site
1298917001640	tetramer interface [polypeptide binding]; other site
1298917001641	PYR/PP interface [polypeptide binding]; other site
1298917001642	TPP binding site [chemical binding]; other site
1298917001643	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1298917001644	TPP-binding site; other site
1298917001645	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1298917001646	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1298917001647	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1298917001648	substrate binding site [chemical binding]; other site
1298917001649	oxyanion hole (OAH) forming residues; other site
1298917001650	trimer interface [polypeptide binding]; other site
1298917001651	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
1298917001652	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1298917001653	active site
1298917001654	signal transduction protein PmrD; Provisional; Region: PRK15450
1298917001655	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1298917001656	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1298917001657	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1298917001658	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1298917001659	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1298917001660	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1298917001661	putative active site [active]
1298917001662	putative catalytic site [active]
1298917001663	putative Zn binding site [ion binding]; other site
1298917001664	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1298917001665	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1298917001666	active site
1298917001667	substrate binding site [chemical binding]; other site
1298917001668	cosubstrate binding site; other site
1298917001669	catalytic site [active]
1298917001670	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1298917001671	active site
1298917001672	hexamer interface [polypeptide binding]; other site
1298917001673	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1298917001674	NAD binding site [chemical binding]; other site
1298917001675	substrate binding site [chemical binding]; other site
1298917001676	active site
1298917001677	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1298917001678	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1298917001679	Ligand binding site; other site
1298917001680	Putative Catalytic site; other site
1298917001681	DXD motif; other site
1298917001682	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1298917001683	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1298917001684	inhibitor-cofactor binding pocket; inhibition site
1298917001685	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917001686	catalytic residue [active]
1298917001687	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1298917001688	catalytic core [active]
1298917001689	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1298917001690	YfaZ precursor; Region: YfaZ; pfam07437
1298917001691	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1298917001692	hypothetical protein; Provisional; Region: PRK03673
1298917001693	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1298917001694	putative MPT binding site; other site
1298917001695	Competence-damaged protein; Region: CinA; cl00666
1298917001696	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1298917001697	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1298917001698	Bacterial transcriptional regulator; Region: IclR; pfam01614
1298917001699	L-rhamnonate dehydratase; Provisional; Region: PRK15440
1298917001700	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
1298917001701	putative active site pocket [active]
1298917001702	putative metal binding site [ion binding]; other site
1298917001703	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001704	D-galactonate transporter; Region: 2A0114; TIGR00893
1298917001705	putative substrate translocation pore; other site
1298917001706	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
1298917001707	deubiquitinase SseL; Provisional; Region: PRK14848
1298917001708	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1298917001709	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1298917001710	Cysteine-rich domain; Region: CCG; pfam02754
1298917001711	Cysteine-rich domain; Region: CCG; pfam02754
1298917001712	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1298917001713	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1298917001714	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1298917001715	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1298917001716	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1298917001717	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1298917001718	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001719	putative substrate translocation pore; other site
1298917001720	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1298917001721	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1298917001722	active site
1298917001723	metal binding site [ion binding]; metal-binding site
1298917001724	catalytic site [active]
1298917001725	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
1298917001726	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917001727	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1298917001728	dimerization interface [polypeptide binding]; other site
1298917001729	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1298917001730	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001731	putative substrate translocation pore; other site
1298917001732	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1298917001733	dimer interface [polypeptide binding]; other site
1298917001734	putative radical transfer pathway; other site
1298917001735	diiron center [ion binding]; other site
1298917001736	tyrosyl radical; other site
1298917001737	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1298917001738	ATP cone domain; Region: ATP-cone; pfam03477
1298917001739	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1298917001740	active site
1298917001741	dimer interface [polypeptide binding]; other site
1298917001742	catalytic residues [active]
1298917001743	effector binding site; other site
1298917001744	R2 peptide binding site; other site
1298917001745	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1298917001746	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917001747	S-adenosylmethionine binding site [chemical binding]; other site
1298917001748	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1298917001749	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917001750	DNA-binding site [nucleotide binding]; DNA binding site
1298917001751	FCD domain; Region: FCD; pfam07729
1298917001752	DNA gyrase subunit A; Validated; Region: PRK05560
1298917001753	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1298917001754	CAP-like domain; other site
1298917001755	active site
1298917001756	primary dimer interface [polypeptide binding]; other site
1298917001757	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1298917001758	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1298917001759	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1298917001760	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1298917001761	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1298917001762	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1298917001763	transcriptional regulator RcsB; Provisional; Region: PRK10840
1298917001764	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917001765	active site
1298917001766	phosphorylation site [posttranslational modification]
1298917001767	intermolecular recognition site; other site
1298917001768	dimerization interface [polypeptide binding]; other site
1298917001769	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917001770	DNA binding residues [nucleotide binding]
1298917001771	dimerization interface [polypeptide binding]; other site
1298917001772	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1298917001773	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917001774	ATP binding site [chemical binding]; other site
1298917001775	G-X-G motif; other site
1298917001776	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1298917001777	putative binding surface; other site
1298917001778	active site
1298917001779	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1298917001780	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1298917001781	trimer interface [polypeptide binding]; other site
1298917001782	eyelet of channel; other site
1298917001783	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1298917001784	ApbE family; Region: ApbE; pfam02424
1298917001785	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1298917001786	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1298917001787	secondary substrate binding site; other site
1298917001788	primary substrate binding site; other site
1298917001789	inhibition loop; other site
1298917001790	dimerization interface [polypeptide binding]; other site
1298917001791	ferredoxin-type protein; Provisional; Region: PRK10194
1298917001792	4Fe-4S binding domain; Region: Fer4; cl02805
1298917001793	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
1298917001794	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1298917001795	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1298917001796	[4Fe-4S] binding site [ion binding]; other site
1298917001797	molybdopterin cofactor binding site; other site
1298917001798	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1298917001799	molybdopterin cofactor binding site; other site
1298917001800	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1298917001801	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1298917001802	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1298917001803	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
1298917001804	cytochrome c-type protein NapC; Provisional; Region: PRK10617
1298917001805	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1298917001806	ABC-type transport system involved in cytochrome c biogenesis, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CcmB; COG2386
1298917001807	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1298917001808	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1298917001809	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1298917001810	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1298917001811	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1298917001812	catalytic residues [active]
1298917001813	central insert; other site
1298917001814	transcriptional regulator NarP; Provisional; Region: PRK10403
1298917001815	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917001816	active site
1298917001817	phosphorylation site [posttranslational modification]
1298917001818	intermolecular recognition site; other site
1298917001819	dimerization interface [polypeptide binding]; other site
1298917001820	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917001821	DNA binding residues [nucleotide binding]
1298917001822	dimerization interface [polypeptide binding]; other site
1298917001823	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
1298917001824	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1298917001825	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1298917001826	hypothetical protein; Provisional; Region: PRK13689
1298917001827	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1298917001828	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1298917001829	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1298917001830	5S rRNA interface [nucleotide binding]; other site
1298917001831	CTC domain interface [polypeptide binding]; other site
1298917001832	L16 interface [polypeptide binding]; other site
1298917001833	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1298917001834	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1298917001835	ATP binding site [chemical binding]; other site
1298917001836	putative Mg++ binding site [ion binding]; other site
1298917001837	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917001838	nucleotide binding region [chemical binding]; other site
1298917001839	ATP-binding site [chemical binding]; other site
1298917001840	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1298917001841	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1298917001842	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1298917001843	RNA binding surface [nucleotide binding]; other site
1298917001844	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1298917001845	active site
1298917001846	uracil binding [chemical binding]; other site
1298917001847	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001848	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1298917001849	putative substrate translocation pore; other site
1298917001850	hypothetical protein; Provisional; Region: PRK11835
1298917001851	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1298917001852	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1298917001853	Walker A/P-loop; other site
1298917001854	ATP binding site [chemical binding]; other site
1298917001855	Q-loop/lid; other site
1298917001856	ABC transporter signature motif; other site
1298917001857	Walker B; other site
1298917001858	D-loop; other site
1298917001859	H-loop/switch region; other site
1298917001860	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1298917001861	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1298917001862	Walker A/P-loop; other site
1298917001863	ATP binding site [chemical binding]; other site
1298917001864	Q-loop/lid; other site
1298917001865	ABC transporter signature motif; other site
1298917001866	Walker B; other site
1298917001867	D-loop; other site
1298917001868	H-loop/switch region; other site
1298917001869	microcin C ABC transporter permease; Provisional; Region: PRK15021
1298917001870	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917001871	dimer interface [polypeptide binding]; other site
1298917001872	conserved gate region; other site
1298917001873	ABC-ATPase subunit interface; other site
1298917001874	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1298917001875	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917001876	dimer interface [polypeptide binding]; other site
1298917001877	conserved gate region; other site
1298917001878	putative PBP binding loops; other site
1298917001879	ABC-ATPase subunit interface; other site
1298917001880	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1298917001881	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1298917001882	phage resistance protein; Provisional; Region: PRK10551
1298917001883	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1298917001884	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917001885	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1298917001886	NlpC/P60 family; Region: NLPC_P60; pfam00877
1298917001887	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1298917001888	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1298917001889	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1298917001890	elongation factor P; Provisional; Region: PRK04542
1298917001891	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1298917001892	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1298917001893	RNA binding site [nucleotide binding]; other site
1298917001894	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1298917001895	RNA binding site [nucleotide binding]; other site
1298917001896	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1298917001897	sugar efflux transporter B; Provisional; Region: PRK15011
1298917001898	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001899	putative substrate translocation pore; other site
1298917001900	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1298917001901	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1298917001902	active site
1298917001903	phosphorylation site [posttranslational modification]
1298917001904	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1298917001905	dimerization domain swap beta strand [polypeptide binding]; other site
1298917001906	regulatory protein interface [polypeptide binding]; other site
1298917001907	active site
1298917001908	regulatory phosphorylation site [posttranslational modification]; other site
1298917001909	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1298917001910	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1298917001911	putative substrate binding site [chemical binding]; other site
1298917001912	putative ATP binding site [chemical binding]; other site
1298917001913	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1298917001914	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1298917001915	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1298917001916	active site
1298917001917	P-loop; other site
1298917001918	phosphorylation site [posttranslational modification]
1298917001919	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1298917001920	endonuclease IV; Provisional; Region: PRK01060
1298917001921	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1298917001922	AP (apurinic/apyrimidinic) site pocket; other site
1298917001923	DNA interaction; other site
1298917001924	Metal-binding active site; metal-binding site
1298917001925	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1298917001926	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1298917001927	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917001928	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1298917001929	putative dimerization interface [polypeptide binding]; other site
1298917001930	lysine transporter; Provisional; Region: PRK10836
1298917001931	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
1298917001932	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1298917001933	N-terminal plug; other site
1298917001934	ligand-binding site [chemical binding]; other site
1298917001935	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1298917001936	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001937	putative substrate translocation pore; other site
1298917001938	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1298917001939	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1298917001940	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917001941	motif II; other site
1298917001942	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1298917001943	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1298917001944	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1298917001945	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917001946	non-specific DNA binding site [nucleotide binding]; other site
1298917001947	salt bridge; other site
1298917001948	sequence-specific DNA binding site [nucleotide binding]; other site
1298917001949	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1298917001950	GTP cyclohydrolase I; Provisional; Region: PLN03044
1298917001951	active site
1298917001952	Predicted membrane protein [Function unknown]; Region: COG2311
1298917001953	hypothetical protein; Provisional; Region: PRK10835
1298917001954	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1298917001955	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917001956	DNA binding site [nucleotide binding]
1298917001957	domain linker motif; other site
1298917001958	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1298917001959	dimerization interface (closed form) [polypeptide binding]; other site
1298917001960	ligand binding site [chemical binding]; other site
1298917001961	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1298917001962	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1298917001963	ligand binding site [chemical binding]; other site
1298917001964	calcium binding site [ion binding]; other site
1298917001965	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1298917001966	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1298917001967	Walker A/P-loop; other site
1298917001968	ATP binding site [chemical binding]; other site
1298917001969	Q-loop/lid; other site
1298917001970	ABC transporter signature motif; other site
1298917001971	Walker B; other site
1298917001972	D-loop; other site
1298917001973	H-loop/switch region; other site
1298917001974	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1298917001975	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1298917001976	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1298917001977	TM-ABC transporter signature motif; other site
1298917001978	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
1298917001979	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
1298917001980	homodimer interface [polypeptide binding]; other site
1298917001981	active site
1298917001982	FMN binding site [chemical binding]; other site
1298917001983	substrate binding site [chemical binding]; other site
1298917001984	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1298917001985	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1298917001986	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917001987	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
1298917001988	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1298917001989	putative active site [active]
1298917001990	hypothetical protein; Provisional; Region: PRK10711
1298917001991	hypothetical protein; Provisional; Region: PRK01821
1298917001992	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917001993	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1298917001994	dimerization interface [polypeptide binding]; other site
1298917001995	benzoate transport; Region: 2A0115; TIGR00895
1298917001996	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917001997	putative substrate translocation pore; other site
1298917001998	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
1298917001999	Cupin domain; Region: Cupin_2; pfam07883
1298917002000	Cupin domain; Region: Cupin_2; pfam07883
1298917002001	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1298917002002	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1298917002003	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
1298917002004	maleylacetoacetate isomerase; Region: maiA; TIGR01262
1298917002005	C-terminal domain interface [polypeptide binding]; other site
1298917002006	GSH binding site (G-site) [chemical binding]; other site
1298917002007	putative dimer interface [polypeptide binding]; other site
1298917002008	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
1298917002009	dimer interface [polypeptide binding]; other site
1298917002010	N-terminal domain interface [polypeptide binding]; other site
1298917002011	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
1298917002012	salicylate hydroxylase; Provisional; Region: PRK08163
1298917002013	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1298917002014	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1298917002015	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1298917002016	FMN binding site [chemical binding]; other site
1298917002017	active site
1298917002018	catalytic residues [active]
1298917002019	substrate binding site [chemical binding]; other site
1298917002020	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
1298917002021	oxidoreductase; Provisional; Region: PRK12743
1298917002022	classical (c) SDRs; Region: SDR_c; cd05233
1298917002023	NAD(P) binding site [chemical binding]; other site
1298917002024	active site
1298917002025	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1298917002026	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1298917002027	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1298917002028	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1298917002029	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1298917002030	D-lactate dehydrogenase; Provisional; Region: PRK11183
1298917002031	FAD binding domain; Region: FAD_binding_4; pfam01565
1298917002032	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1298917002033	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1298917002034	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1298917002035	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1298917002036	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1298917002037	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917002038	dimer interface [polypeptide binding]; other site
1298917002039	conserved gate region; other site
1298917002040	ABC-ATPase subunit interface; other site
1298917002041	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1298917002042	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1298917002043	Walker A/P-loop; other site
1298917002044	ATP binding site [chemical binding]; other site
1298917002045	Q-loop/lid; other site
1298917002046	ABC transporter signature motif; other site
1298917002047	Walker B; other site
1298917002048	D-loop; other site
1298917002049	H-loop/switch region; other site
1298917002050	CBS domain; Region: CBS; pfam00571
1298917002051	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
1298917002052	putative PBP binding loops; other site
1298917002053	ABC-ATPase subunit interface; other site
1298917002054	hypothetical protein; Provisional; Region: PRK13681
1298917002055	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1298917002056	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1298917002057	GAF domain; Region: GAF; pfam01590
1298917002058	Histidine kinase; Region: His_kinase; pfam06580
1298917002059	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917002060	ATP binding site [chemical binding]; other site
1298917002061	Mg2+ binding site [ion binding]; other site
1298917002062	G-X-G motif; other site
1298917002063	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1298917002064	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917002065	active site
1298917002066	phosphorylation site [posttranslational modification]
1298917002067	intermolecular recognition site; other site
1298917002068	dimerization interface [polypeptide binding]; other site
1298917002069	LytTr DNA-binding domain; Region: LytTR; pfam04397
1298917002070	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1298917002071	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1298917002072	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1298917002073	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1298917002074	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1298917002075	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1298917002076	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1298917002077	active site
1298917002078	HIGH motif; other site
1298917002079	KMSKS motif; other site
1298917002080	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1298917002081	tRNA binding surface [nucleotide binding]; other site
1298917002082	anticodon binding site; other site
1298917002083	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1298917002084	dimer interface [polypeptide binding]; other site
1298917002085	putative tRNA-binding site [nucleotide binding]; other site
1298917002086	antiporter inner membrane protein; Provisional; Region: PRK11670
1298917002087	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1298917002088	Walker A motif; other site
1298917002089	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
1298917002090	fimbrial chaperone protein; Provisional; Region: PRK15220
1298917002091	Predicted integral membrane protein [Function unknown]; Region: COG5455
1298917002092	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1298917002093	substrate binding site [chemical binding]; other site
1298917002094	multimerization interface [polypeptide binding]; other site
1298917002095	ATP binding site [chemical binding]; other site
1298917002096	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1298917002097	dimer interface [polypeptide binding]; other site
1298917002098	substrate binding site [chemical binding]; other site
1298917002099	ATP binding site [chemical binding]; other site
1298917002100	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1298917002101	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917002102	DNA-binding site [nucleotide binding]; DNA binding site
1298917002103	UTRA domain; Region: UTRA; pfam07702
1298917002104	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1298917002105	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1298917002106	substrate binding site [chemical binding]; other site
1298917002107	ATP binding site [chemical binding]; other site
1298917002108	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1298917002109	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1298917002110	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1298917002111	putative active site; other site
1298917002112	catalytic residue [active]
1298917002113	lipid kinase; Reviewed; Region: PRK13054
1298917002114	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1298917002115	putative protease; Provisional; Region: PRK15452
1298917002116	Peptidase family U32; Region: Peptidase_U32; pfam01136
1298917002117	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
1298917002118	PcfJ-like protein; Region: PcfJ; pfam14284
1298917002119	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1298917002120	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917002121	active site
1298917002122	phosphorylation site [posttranslational modification]
1298917002123	intermolecular recognition site; other site
1298917002124	dimerization interface [polypeptide binding]; other site
1298917002125	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917002126	DNA binding site [nucleotide binding]
1298917002127	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1298917002128	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917002129	dimerization interface [polypeptide binding]; other site
1298917002130	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917002131	dimer interface [polypeptide binding]; other site
1298917002132	phosphorylation site [posttranslational modification]
1298917002133	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917002134	ATP binding site [chemical binding]; other site
1298917002135	Mg2+ binding site [ion binding]; other site
1298917002136	G-X-G motif; other site
1298917002137	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1298917002138	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1298917002139	Protein export membrane protein; Region: SecD_SecF; cl14618
1298917002140	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1298917002141	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1298917002142	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917002143	putative chaperone; Provisional; Region: PRK11678
1298917002144	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1298917002145	nucleotide binding site [chemical binding]; other site
1298917002146	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1298917002147	SBD interface [polypeptide binding]; other site
1298917002148	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1298917002149	AlkA N-terminal domain; Region: AlkA_N; pfam06029
1298917002150	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1298917002151	minor groove reading motif; other site
1298917002152	helix-hairpin-helix signature motif; other site
1298917002153	substrate binding pocket [chemical binding]; other site
1298917002154	active site
1298917002155	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
1298917002156	PAS domain S-box; Region: sensory_box; TIGR00229
1298917002157	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1298917002158	putative active site [active]
1298917002159	heme pocket [chemical binding]; other site
1298917002160	PAS domain S-box; Region: sensory_box; TIGR00229
1298917002161	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1298917002162	putative active site [active]
1298917002163	heme pocket [chemical binding]; other site
1298917002164	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1298917002165	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1298917002166	metal binding site [ion binding]; metal-binding site
1298917002167	active site
1298917002168	I-site; other site
1298917002169	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917002170	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1298917002171	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1298917002172	ATP-binding site [chemical binding]; other site
1298917002173	Sugar specificity; other site
1298917002174	Pyrimidine base specificity; other site
1298917002175	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1298917002176	trimer interface [polypeptide binding]; other site
1298917002177	active site
1298917002178	putative assembly protein; Provisional; Region: PRK10833
1298917002179	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1298917002180	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1298917002181	FOG: CBS domain [General function prediction only]; Region: COG0517
1298917002182	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1298917002183	Transporter associated domain; Region: CorC_HlyC; smart01091
1298917002184	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1298917002185	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1298917002186	active site
1298917002187	putative glycosyl transferase; Provisional; Region: PRK10018
1298917002188	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1298917002189	active site
1298917002190	putative acyl transferase; Provisional; Region: PRK10191
1298917002191	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1298917002192	trimer interface [polypeptide binding]; other site
1298917002193	active site
1298917002194	substrate binding site [chemical binding]; other site
1298917002195	CoA binding site [chemical binding]; other site
1298917002196	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
1298917002197	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1298917002198	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1298917002199	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
1298917002200	putative glycosyl transferase; Provisional; Region: PRK10063
1298917002201	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1298917002202	metal-binding site
1298917002203	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
1298917002204	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1298917002205	putative trimer interface [polypeptide binding]; other site
1298917002206	putative active site [active]
1298917002207	putative substrate binding site [chemical binding]; other site
1298917002208	putative CoA binding site [chemical binding]; other site
1298917002209	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1298917002210	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1298917002211	NADP-binding site; other site
1298917002212	homotetramer interface [polypeptide binding]; other site
1298917002213	substrate binding site [chemical binding]; other site
1298917002214	homodimer interface [polypeptide binding]; other site
1298917002215	active site
1298917002216	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1298917002217	active site
1298917002218	GDP-Mannose binding site [chemical binding]; other site
1298917002219	dimer interface [polypeptide binding]; other site
1298917002220	modified nudix motif
1298917002221	metal binding site [ion binding]; metal-binding site
1298917002222	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
1298917002223	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1298917002224	phosphomannomutase CpsG; Provisional; Region: PRK15414
1298917002225	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1298917002226	active site
1298917002227	substrate binding site [chemical binding]; other site
1298917002228	metal binding site [ion binding]; metal-binding site
1298917002229	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
1298917002230	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
1298917002231	colanic acid exporter; Provisional; Region: PRK10459
1298917002232	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1298917002233	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; cl09156
1298917002234	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
1298917002235	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
1298917002236	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1298917002237	putative ADP-binding pocket [chemical binding]; other site
1298917002238	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
1298917002239	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1298917002240	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1298917002241	active site
1298917002242	tetramer interface; other site
1298917002243	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
1298917002244	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1298917002245	NAD binding site [chemical binding]; other site
1298917002246	substrate binding site [chemical binding]; other site
1298917002247	homodimer interface [polypeptide binding]; other site
1298917002248	active site
1298917002249	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
1298917002250	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1298917002251	NADP binding site [chemical binding]; other site
1298917002252	active site
1298917002253	putative substrate binding site [chemical binding]; other site
1298917002254	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
1298917002255	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1298917002256	substrate binding site; other site
1298917002257	tetramer interface; other site
1298917002258	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1298917002259	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1298917002260	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1298917002261	substrate binding site; other site
1298917002262	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
1298917002263	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
1298917002264	NAD binding site [chemical binding]; other site
1298917002265	homotetramer interface [polypeptide binding]; other site
1298917002266	homodimer interface [polypeptide binding]; other site
1298917002267	substrate binding site [chemical binding]; other site
1298917002268	active site
1298917002269	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1298917002270	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1298917002271	inhibitor-cofactor binding pocket; inhibition site
1298917002272	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917002273	catalytic residue [active]
1298917002274	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1298917002275	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1298917002276	NAD(P) binding site [chemical binding]; other site
1298917002277	active site
1298917002278	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
1298917002279	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1298917002280	NAD binding site [chemical binding]; other site
1298917002281	homotetramer interface [polypeptide binding]; other site
1298917002282	homodimer interface [polypeptide binding]; other site
1298917002283	active site
1298917002284	substrate binding site [chemical binding]; other site
1298917002285	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1298917002286	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
1298917002287	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1298917002288	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1298917002289	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1298917002290	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1298917002291	active site
1298917002292	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1298917002293	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1298917002294	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1298917002295	Substrate binding site; other site
1298917002296	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1298917002297	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1298917002298	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
1298917002299	active site
1298917002300	substrate binding site [chemical binding]; other site
1298917002301	metal binding site [ion binding]; metal-binding site
1298917002302	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
1298917002303	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1298917002304	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1298917002305	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1298917002306	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1298917002307	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1298917002308	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1298917002309	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1298917002310	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1298917002311	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1298917002312	chain length determinant protein WzzB; Provisional; Region: PRK15471
1298917002313	Chain length determinant protein; Region: Wzz; cl15801
1298917002314	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1298917002315	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1298917002316	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1298917002317	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1298917002318	metal binding site [ion binding]; metal-binding site
1298917002319	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1298917002320	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1298917002321	substrate binding site [chemical binding]; other site
1298917002322	glutamase interaction surface [polypeptide binding]; other site
1298917002323	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1298917002324	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1298917002325	catalytic residues [active]
1298917002326	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1298917002327	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1298917002328	putative active site [active]
1298917002329	oxyanion strand; other site
1298917002330	catalytic triad [active]
1298917002331	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1298917002332	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917002333	active site
1298917002334	motif I; other site
1298917002335	motif II; other site
1298917002336	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1298917002337	putative active site pocket [active]
1298917002338	4-fold oligomerization interface [polypeptide binding]; other site
1298917002339	metal binding residues [ion binding]; metal-binding site
1298917002340	3-fold/trimer interface [polypeptide binding]; other site
1298917002341	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1298917002342	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917002343	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917002344	homodimer interface [polypeptide binding]; other site
1298917002345	catalytic residue [active]
1298917002346	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1298917002347	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1298917002348	NAD binding site [chemical binding]; other site
1298917002349	dimerization interface [polypeptide binding]; other site
1298917002350	product binding site; other site
1298917002351	substrate binding site [chemical binding]; other site
1298917002352	zinc binding site [ion binding]; other site
1298917002353	catalytic residues [active]
1298917002354	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917002355	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1298917002356	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1298917002357	dimerization interface [polypeptide binding]; other site
1298917002358	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1298917002359	exonuclease I; Provisional; Region: sbcB; PRK11779
1298917002360	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1298917002361	active site
1298917002362	catalytic site [active]
1298917002363	substrate binding site [chemical binding]; other site
1298917002364	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1298917002365	SopA-like central domain; Region: SopA; pfam13981
1298917002366	SopA-like catalytic domain; Region: SopA_C; pfam13979
1298917002367	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
1298917002368	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
1298917002369	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
1298917002370	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1298917002371	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1298917002372	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1298917002373	DNA gyrase inhibitor; Provisional; Region: PRK10016
1298917002374	Predicted membrane protein [Function unknown]; Region: COG1289
1298917002375	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1298917002376	hypothetical protein; Provisional; Region: PRK05423
1298917002377	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
1298917002378	propionate kinase; Reviewed; Region: PRK12397
1298917002379	propionate/acetate kinase; Provisional; Region: PRK12379
1298917002380	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
1298917002381	G3 box; other site
1298917002382	Switch II region; other site
1298917002383	GTP/Mg2+ binding site [chemical binding]; other site
1298917002384	G4 box; other site
1298917002385	G5 box; other site
1298917002386	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1298917002387	putative hexamer interface [polypeptide binding]; other site
1298917002388	putative hexagonal pore; other site
1298917002389	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
1298917002390	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1298917002391	putative hexamer interface [polypeptide binding]; other site
1298917002392	putative hexagonal pore; other site
1298917002393	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1298917002394	putative hexamer interface [polypeptide binding]; other site
1298917002395	putative hexagonal pore; other site
1298917002396	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1298917002397	SLBB domain; Region: SLBB; pfam10531
1298917002398	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1298917002399	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
1298917002400	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1298917002401	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
1298917002402	putative active site [active]
1298917002403	metal binding site [ion binding]; metal-binding site
1298917002404	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1298917002405	putative catalytic cysteine [active]
1298917002406	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
1298917002407	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
1298917002408	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1298917002409	Hexamer/Pentamer interface [polypeptide binding]; other site
1298917002410	central pore; other site
1298917002411	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
1298917002412	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
1298917002413	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1298917002414	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1298917002415	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1298917002416	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
1298917002417	putative hexamer interface [polypeptide binding]; other site
1298917002418	putative hexagonal pore; other site
1298917002419	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1298917002420	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1298917002421	Hexamer interface [polypeptide binding]; other site
1298917002422	Putative hexagonal pore residue; other site
1298917002423	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
1298917002424	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
1298917002425	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
1298917002426	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
1298917002427	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
1298917002428	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
1298917002429	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
1298917002430	alpha-beta subunit interface [polypeptide binding]; other site
1298917002431	alpha-gamma subunit interface [polypeptide binding]; other site
1298917002432	active site
1298917002433	substrate and K+ binding site; other site
1298917002434	K+ binding site [ion binding]; other site
1298917002435	cobalamin binding site [chemical binding]; other site
1298917002436	propanediol utilization protein PduB; Provisional; Region: PRK15415
1298917002437	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
1298917002438	putative hexamer interface [polypeptide binding]; other site
1298917002439	putative hexagonal pore; other site
1298917002440	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
1298917002441	putative hexamer interface [polypeptide binding]; other site
1298917002442	putative hexagonal pore; other site
1298917002443	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1298917002444	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1298917002445	Hexamer interface [polypeptide binding]; other site
1298917002446	Putative hexagonal pore residue; other site
1298917002447	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1298917002448	amphipathic channel; other site
1298917002449	Asn-Pro-Ala signature motifs; other site
1298917002450	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1298917002451	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1298917002452	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1298917002453	catalytic triad [active]
1298917002454	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
1298917002455	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
1298917002456	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1298917002457	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1298917002458	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1298917002459	active site
1298917002460	putative homodimer interface [polypeptide binding]; other site
1298917002461	SAM binding site [chemical binding]; other site
1298917002462	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
1298917002463	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917002464	S-adenosylmethionine binding site [chemical binding]; other site
1298917002465	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1298917002466	active site
1298917002467	SAM binding site [chemical binding]; other site
1298917002468	homodimer interface [polypeptide binding]; other site
1298917002469	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1298917002470	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1298917002471	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1298917002472	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1298917002473	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1298917002474	active site
1298917002475	SAM binding site [chemical binding]; other site
1298917002476	homodimer interface [polypeptide binding]; other site
1298917002477	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1298917002478	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
1298917002479	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
1298917002480	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
1298917002481	active site
1298917002482	C-terminal domain interface [polypeptide binding]; other site
1298917002483	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
1298917002484	active site
1298917002485	N-terminal domain interface [polypeptide binding]; other site
1298917002486	cobalt transport protein CbiM; Validated; Region: PRK08319
1298917002487	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
1298917002488	cobalt transport protein CbiN; Provisional; Region: PRK02898
1298917002489	cobalt transport protein CbiQ; Provisional; Region: PRK15485
1298917002490	cobyric acid synthase; Provisional; Region: PRK00784
1298917002491	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1298917002492	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1298917002493	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1298917002494	catalytic triad [active]
1298917002495	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1298917002496	homotrimer interface [polypeptide binding]; other site
1298917002497	Walker A motif; other site
1298917002498	GTP binding site [chemical binding]; other site
1298917002499	Walker B motif; other site
1298917002500	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1298917002501	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1298917002502	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1298917002503	putative dimer interface [polypeptide binding]; other site
1298917002504	active site pocket [active]
1298917002505	putative cataytic base [active]
1298917002506	L,D-transpeptidase; Provisional; Region: PRK10190
1298917002507	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1298917002508	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1298917002509	AMP nucleosidase; Provisional; Region: PRK08292
1298917002510	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1298917002511	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1298917002512	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
1298917002513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1298917002514	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1298917002515	Sel1 repeat; Region: Sel1; pfam08238
1298917002516	Sel1-like repeats; Region: SEL1; smart00671
1298917002517	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
1298917002518	Integrase; Region: Integrase_1; pfam12835
1298917002519	putative protease; Region: PHA00666
1298917002520	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1298917002521	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
1298917002522	active site
1298917002523	NTP binding site [chemical binding]; other site
1298917002524	metal binding triad [ion binding]; metal-binding site
1298917002525	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1298917002526	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1298917002527	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1298917002528	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917002529	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
1298917002530	MobA/MobL family; Region: MobA_MobL; pfam03389
1298917002531	Conjugal transfer protein TraD; Region: TraD; pfam06412
1298917002532	PilS N terminal; Region: PilS; pfam08805
1298917002533	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
1298917002534	Phage Tail Collar Domain; Region: Collar; pfam07484
1298917002535	TIR domain; Region: TIR_2; pfam13676
1298917002536	integrase; Provisional; Region: PRK09692
1298917002537	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1298917002538	active site
1298917002539	Int/Topo IB signature motif; other site
1298917002540	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1298917002541	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1298917002542	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1298917002543	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1298917002544	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1298917002545	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1298917002546	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1298917002547	DNA-binding interface [nucleotide binding]; DNA binding site
1298917002548	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1298917002549	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1298917002550	putative ligand binding site [chemical binding]; other site
1298917002551	NAD binding site [chemical binding]; other site
1298917002552	dimerization interface [polypeptide binding]; other site
1298917002553	catalytic site [active]
1298917002554	putative hydrolase; Validated; Region: PRK09248
1298917002555	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1298917002556	active site
1298917002557	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1298917002558	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1298917002559	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
1298917002560	curli assembly protein CsgF; Provisional; Region: PRK10050
1298917002561	curli assembly protein CsgE; Provisional; Region: PRK10386
1298917002562	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1298917002563	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917002564	DNA binding residues [nucleotide binding]
1298917002565	dimerization interface [polypeptide binding]; other site
1298917002566	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1298917002567	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1298917002568	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1298917002569	major curlin subunit; Provisional; Region: csgA; PRK10051
1298917002570	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1298917002571	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
1298917002572	Fimbrial protein; Region: Fimbrial; cl01416
1298917002573	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1298917002574	putative ADP-ribose binding site [chemical binding]; other site
1298917002575	putative active site [active]
1298917002576	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
1298917002577	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1298917002578	putative active site [active]
1298917002579	catalytic site [active]
1298917002580	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1298917002581	putative active site [active]
1298917002582	catalytic site [active]
1298917002583	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1298917002584	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1298917002585	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1298917002586	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
1298917002587	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1298917002588	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1298917002589	Ligand binding site; other site
1298917002590	DXD motif; other site
1298917002591	lipoprotein; Provisional; Region: PRK10175
1298917002592	drug efflux system protein MdtG; Provisional; Region: PRK09874
1298917002593	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917002594	putative substrate translocation pore; other site
1298917002595	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1298917002596	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1298917002597	putative acyl-acceptor binding pocket; other site
1298917002598	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1298917002599	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1298917002600	active site residue [active]
1298917002601	hypothetical protein; Provisional; Region: PRK03757
1298917002602	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1298917002603	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
1298917002604	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1298917002605	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1298917002606	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1298917002607	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1298917002608	active site
1298917002609	substrate binding pocket [chemical binding]; other site
1298917002610	dimer interface [polypeptide binding]; other site
1298917002611	lipoprotein; Provisional; Region: PRK10598
1298917002612	glutaredoxin 2; Provisional; Region: PRK10387
1298917002613	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1298917002614	C-terminal domain interface [polypeptide binding]; other site
1298917002615	GSH binding site (G-site) [chemical binding]; other site
1298917002616	catalytic residues [active]
1298917002617	putative dimer interface [polypeptide binding]; other site
1298917002618	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1298917002619	N-terminal domain interface [polypeptide binding]; other site
1298917002620	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1298917002621	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917002622	putative substrate translocation pore; other site
1298917002623	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1298917002624	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1298917002625	hypothetical protein; Provisional; Region: PRK11239
1298917002626	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1298917002627	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1298917002628	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1298917002629	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1298917002630	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1298917002631	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1298917002632	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
1298917002633	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
1298917002634	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
1298917002635	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1298917002636	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1298917002637	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1298917002638	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1298917002639	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1298917002640	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1298917002641	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1298917002642	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
1298917002643	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1298917002644	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1298917002645	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1298917002646	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1298917002647	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1298917002648	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1298917002649	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1298917002650	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1298917002651	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1298917002652	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1298917002653	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1298917002654	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1298917002655	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1298917002656	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1298917002657	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1298917002658	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1298917002659	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1298917002660	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1298917002661	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1298917002662	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1298917002663	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1298917002664	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1298917002665	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1298917002666	RNA binding surface [nucleotide binding]; other site
1298917002667	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1298917002668	active site
1298917002669	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1298917002670	Maf-like protein; Region: Maf; pfam02545
1298917002671	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1298917002672	active site
1298917002673	dimer interface [polypeptide binding]; other site
1298917002674	hypothetical protein; Provisional; Region: PRK11193
1298917002675	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1298917002676	putative phosphate acyltransferase; Provisional; Region: PRK05331
1298917002677	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1298917002678	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1298917002679	dimer interface [polypeptide binding]; other site
1298917002680	active site
1298917002681	CoA binding pocket [chemical binding]; other site
1298917002682	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1298917002683	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1298917002684	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1298917002685	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1298917002686	NAD(P) binding site [chemical binding]; other site
1298917002687	homotetramer interface [polypeptide binding]; other site
1298917002688	homodimer interface [polypeptide binding]; other site
1298917002689	active site
1298917002690	acyl carrier protein; Provisional; Region: acpP; PRK00982
1298917002691	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1298917002692	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1298917002693	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917002694	catalytic residue [active]
1298917002695	conserved hypothetical protein, YceG family; Region: TIGR00247
1298917002696	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1298917002697	dimerization interface [polypeptide binding]; other site
1298917002698	thymidylate kinase; Validated; Region: tmk; PRK00698
1298917002699	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1298917002700	TMP-binding site; other site
1298917002701	ATP-binding site [chemical binding]; other site
1298917002702	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1298917002703	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1298917002704	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1298917002705	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1298917002706	active site
1298917002707	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1298917002708	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1298917002709	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1298917002710	active site turn [active]
1298917002711	phosphorylation site [posttranslational modification]
1298917002712	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1298917002713	nucleotide binding site/active site [active]
1298917002714	HIT family signature motif; other site
1298917002715	catalytic residue [active]
1298917002716	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1298917002717	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1298917002718	putative dimer interface [polypeptide binding]; other site
1298917002719	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1298917002720	thiamine kinase; Region: ycfN_thiK; TIGR02721
1298917002721	thiamine kinase; Provisional; Region: thiK; PRK10271
1298917002722	substrate binding site [chemical binding]; other site
1298917002723	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1298917002724	beta-hexosaminidase; Provisional; Region: PRK05337
1298917002725	hypothetical protein; Provisional; Region: PRK04940
1298917002726	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1298917002727	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917002728	hypothetical protein; Provisional; Region: PRK11280
1298917002729	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1298917002730	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917002731	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1298917002732	L,D-transpeptidase; Provisional; Region: PRK10190
1298917002733	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1298917002734	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1298917002735	transcription-repair coupling factor; Provisional; Region: PRK10689
1298917002736	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1298917002737	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1298917002738	ATP binding site [chemical binding]; other site
1298917002739	putative Mg++ binding site [ion binding]; other site
1298917002740	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917002741	nucleotide binding region [chemical binding]; other site
1298917002742	ATP-binding site [chemical binding]; other site
1298917002743	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1298917002744	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1298917002745	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1298917002746	FtsX-like permease family; Region: FtsX; pfam02687
1298917002747	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1298917002748	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1298917002749	Walker A/P-loop; other site
1298917002750	ATP binding site [chemical binding]; other site
1298917002751	Q-loop/lid; other site
1298917002752	ABC transporter signature motif; other site
1298917002753	Walker B; other site
1298917002754	D-loop; other site
1298917002755	H-loop/switch region; other site
1298917002756	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1298917002757	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1298917002758	FtsX-like permease family; Region: FtsX; pfam02687
1298917002759	fructokinase; Reviewed; Region: PRK09557
1298917002760	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1298917002761	nucleotide binding site [chemical binding]; other site
1298917002762	NAD-dependent deacetylase; Provisional; Region: PRK00481
1298917002763	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1298917002764	NAD+ binding site [chemical binding]; other site
1298917002765	substrate binding site [chemical binding]; other site
1298917002766	Zn binding site [ion binding]; other site
1298917002767	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1298917002768	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1298917002769	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1298917002770	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917002771	dimer interface [polypeptide binding]; other site
1298917002772	conserved gate region; other site
1298917002773	putative PBP binding loops; other site
1298917002774	ABC-ATPase subunit interface; other site
1298917002775	Sif protein; Region: Sif; pfam06767
1298917002776	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1298917002777	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917002778	dimer interface [polypeptide binding]; other site
1298917002779	conserved gate region; other site
1298917002780	putative PBP binding loops; other site
1298917002781	ABC-ATPase subunit interface; other site
1298917002782	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1298917002783	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917002784	Walker A/P-loop; other site
1298917002785	ATP binding site [chemical binding]; other site
1298917002786	Q-loop/lid; other site
1298917002787	ABC transporter signature motif; other site
1298917002788	Walker B; other site
1298917002789	D-loop; other site
1298917002790	H-loop/switch region; other site
1298917002791	TOBE domain; Region: TOBE_2; pfam08402
1298917002792	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1298917002793	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1298917002794	metal binding site [ion binding]; metal-binding site
1298917002795	dimer interface [polypeptide binding]; other site
1298917002796	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1298917002797	Cupin domain; Region: Cupin_2; cl17218
1298917002798	sensor protein PhoQ; Provisional; Region: PRK10815
1298917002799	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1298917002800	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1298917002801	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917002802	ATP binding site [chemical binding]; other site
1298917002803	Mg2+ binding site [ion binding]; other site
1298917002804	G-X-G motif; other site
1298917002805	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1298917002806	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917002807	active site
1298917002808	phosphorylation site [posttranslational modification]
1298917002809	intermolecular recognition site; other site
1298917002810	dimerization interface [polypeptide binding]; other site
1298917002811	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917002812	DNA binding site [nucleotide binding]
1298917002813	adenylosuccinate lyase; Provisional; Region: PRK09285
1298917002814	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1298917002815	tetramer interface [polypeptide binding]; other site
1298917002816	active site
1298917002817	putative lysogenization regulator; Reviewed; Region: PRK00218
1298917002818	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1298917002819	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1298917002820	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1298917002821	nudix motif; other site
1298917002822	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
1298917002823	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1298917002824	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1298917002825	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1298917002826	active site
1298917002827	isocitrate dehydrogenase; Validated; Region: PRK07362
1298917002828	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1298917002829	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
1298917002830	DinI-like family; Region: DinI; pfam06183
1298917002831	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1298917002832	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
1298917002833	putative sugar binding sites [chemical binding]; other site
1298917002834	Q-X-W motif; other site
1298917002835	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1298917002836	DNA-binding site [nucleotide binding]; DNA binding site
1298917002837	RNA-binding motif; other site
1298917002838	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1298917002839	lysozyme inhibitor; Provisional; Region: PRK13791
1298917002840	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1298917002841	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1298917002842	putative dimer interface [polypeptide binding]; other site
1298917002843	TRL-like protein family; Region: TRL; pfam13146
1298917002844	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
1298917002845	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1298917002846	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1298917002847	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917002848	dimer interface [polypeptide binding]; other site
1298917002849	conserved gate region; other site
1298917002850	ABC-ATPase subunit interface; other site
1298917002851	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1298917002852	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917002853	dimer interface [polypeptide binding]; other site
1298917002854	conserved gate region; other site
1298917002855	putative PBP binding loops; other site
1298917002856	ABC-ATPase subunit interface; other site
1298917002857	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1298917002858	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
1298917002859	Walker A/P-loop; other site
1298917002860	ATP binding site [chemical binding]; other site
1298917002861	Q-loop/lid; other site
1298917002862	ABC transporter signature motif; other site
1298917002863	Walker B; other site
1298917002864	D-loop; other site
1298917002865	H-loop/switch region; other site
1298917002866	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917002867	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1298917002868	Walker A/P-loop; other site
1298917002869	ATP binding site [chemical binding]; other site
1298917002870	Q-loop/lid; other site
1298917002871	ABC transporter signature motif; other site
1298917002872	Walker B; other site
1298917002873	D-loop; other site
1298917002874	H-loop/switch region; other site
1298917002875	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1298917002876	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1298917002877	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
1298917002878	dimerization interface [polypeptide binding]; other site
1298917002879	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1298917002880	aminoglycoside resistance protein; Provisional; Region: PRK13746
1298917002881	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1298917002882	active site
1298917002883	NTP binding site [chemical binding]; other site
1298917002884	metal binding triad [ion binding]; metal-binding site
1298917002885	antibiotic binding site [chemical binding]; other site
1298917002886	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1298917002887	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917002888	DNA binding residues [nucleotide binding]
1298917002889	transcriptional regulator MirA; Provisional; Region: PRK15043
1298917002890	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
1298917002891	DNA binding residues [nucleotide binding]
1298917002892	dimer interface [polypeptide binding]; other site
1298917002893	Pleckstrin homology-like domain; Region: PH-like; cl17171
1298917002894	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1298917002895	chorismate mutase; Provisional; Region: PRK08055
1298917002896	leucine export protein LeuE; Provisional; Region: PRK10958
1298917002897	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1298917002898	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1298917002899	hypothetical protein; Provisional; Region: PRK10457
1298917002900	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1298917002901	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1298917002902	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1298917002903	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1298917002904	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1298917002905	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917002906	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1298917002907	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917002908	Predicted membrane protein [Function unknown]; Region: COG2707
1298917002909	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1298917002910	putative deacylase active site [active]
1298917002911	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1298917002912	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1298917002913	metal binding site [ion binding]; metal-binding site
1298917002914	active site
1298917002915	I-site; other site
1298917002916	hypothetical protein; Provisional; Region: PRK05325
1298917002917	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1298917002918	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1298917002919	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1298917002920	active site
1298917002921	catalytic tetrad [active]
1298917002922	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1298917002923	active site
1298917002924	phosphate binding residues; other site
1298917002925	catalytic residues [active]
1298917002926	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1298917002927	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1298917002928	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1298917002929	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1298917002930	SelR domain; Region: SelR; pfam01641
1298917002931	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1298917002932	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1298917002933	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
1298917002934	putative NAD(P) binding site [chemical binding]; other site
1298917002935	catalytic Zn binding site [ion binding]; other site
1298917002936	structural Zn binding site [ion binding]; other site
1298917002937	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917002938	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917002939	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1298917002940	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
1298917002941	inhibitor binding site; inhibition site
1298917002942	catalytic Zn binding site [ion binding]; other site
1298917002943	structural Zn binding site [ion binding]; other site
1298917002944	NADP binding site [chemical binding]; other site
1298917002945	tetramer interface [polypeptide binding]; other site
1298917002946	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1298917002947	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1298917002948	intersubunit interface [polypeptide binding]; other site
1298917002949	active site
1298917002950	zinc binding site [ion binding]; other site
1298917002951	Na+ binding site [ion binding]; other site
1298917002952	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1298917002953	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1298917002954	substrate binding site [chemical binding]; other site
1298917002955	ATP binding site [chemical binding]; other site
1298917002956	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1298917002957	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1298917002958	active site
1298917002959	catalytic tetrad [active]
1298917002960	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1298917002961	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1298917002962	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917002963	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917002964	putative substrate translocation pore; other site
1298917002965	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917002966	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1298917002967	Isochorismatase family; Region: Isochorismatase; pfam00857
1298917002968	catalytic triad [active]
1298917002969	metal binding site [ion binding]; metal-binding site
1298917002970	conserved cis-peptide bond; other site
1298917002971	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1298917002972	active site
1298917002973	homodimer interface [polypeptide binding]; other site
1298917002974	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1298917002975	putative FMN binding site [chemical binding]; other site
1298917002976	selenophosphate synthetase; Provisional; Region: PRK00943
1298917002977	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1298917002978	dimerization interface [polypeptide binding]; other site
1298917002979	putative ATP binding site [chemical binding]; other site
1298917002980	glutamate dehydrogenase; Provisional; Region: PRK09414
1298917002981	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1298917002982	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1298917002983	NAD(P) binding site [chemical binding]; other site
1298917002984	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1298917002985	active site
1298917002986	8-oxo-dGMP binding site [chemical binding]; other site
1298917002987	nudix motif; other site
1298917002988	metal binding site [ion binding]; metal-binding site
1298917002989	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1298917002990	putative catalytic site [active]
1298917002991	putative phosphate binding site [ion binding]; other site
1298917002992	active site
1298917002993	metal binding site A [ion binding]; metal-binding site
1298917002994	DNA binding site [nucleotide binding]
1298917002995	putative AP binding site [nucleotide binding]; other site
1298917002996	putative metal binding site B [ion binding]; other site
1298917002997	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1298917002998	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1298917002999	inhibitor-cofactor binding pocket; inhibition site
1298917003000	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917003001	catalytic residue [active]
1298917003002	Arginine N-succinyltransferase beta subunit; Region: AstA; cl11440
1298917003003	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1298917003004	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1298917003005	NAD(P) binding site [chemical binding]; other site
1298917003006	catalytic residues [active]
1298917003007	succinylarginine dihydrolase; Provisional; Region: PRK13281
1298917003008	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1298917003009	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1298917003010	putative active site [active]
1298917003011	Zn binding site [ion binding]; other site
1298917003012	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1298917003013	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1298917003014	GIY-YIG motif/motif A; other site
1298917003015	active site
1298917003016	catalytic site [active]
1298917003017	putative DNA binding site [nucleotide binding]; other site
1298917003018	metal binding site [ion binding]; metal-binding site
1298917003019	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1298917003020	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1298917003021	homodimer interface [polypeptide binding]; other site
1298917003022	NAD binding pocket [chemical binding]; other site
1298917003023	ATP binding pocket [chemical binding]; other site
1298917003024	Mg binding site [ion binding]; other site
1298917003025	active-site loop [active]
1298917003026	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1298917003027	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1298917003028	active site
1298917003029	P-loop; other site
1298917003030	phosphorylation site [posttranslational modification]
1298917003031	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1298917003032	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1298917003033	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1298917003034	methionine cluster; other site
1298917003035	active site
1298917003036	phosphorylation site [posttranslational modification]
1298917003037	metal binding site [ion binding]; metal-binding site
1298917003038	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1298917003039	Cupin domain; Region: Cupin_2; pfam07883
1298917003040	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917003041	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1298917003042	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1298917003043	NAD binding site [chemical binding]; other site
1298917003044	sugar binding site [chemical binding]; other site
1298917003045	divalent metal binding site [ion binding]; other site
1298917003046	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1298917003047	dimer interface [polypeptide binding]; other site
1298917003048	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1298917003049	putative active site [active]
1298917003050	YdjC motif; other site
1298917003051	Mg binding site [ion binding]; other site
1298917003052	putative homodimer interface [polypeptide binding]; other site
1298917003053	hydroperoxidase II; Provisional; Region: katE; PRK11249
1298917003054	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1298917003055	tetramer interface [polypeptide binding]; other site
1298917003056	heme binding pocket [chemical binding]; other site
1298917003057	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1298917003058	domain interactions; other site
1298917003059	cell division modulator; Provisional; Region: PRK10113
1298917003060	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1298917003061	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1298917003062	inner membrane protein; Provisional; Region: PRK11648
1298917003063	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1298917003064	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1298917003065	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917003066	motif II; other site
1298917003067	YniB-like protein; Region: YniB; pfam14002
1298917003068	Phosphotransferase enzyme family; Region: APH; pfam01636
1298917003069	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1298917003070	active site
1298917003071	ATP binding site [chemical binding]; other site
1298917003072	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1298917003073	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1298917003074	6-phosphofructokinase 2; Provisional; Region: PRK10294
1298917003075	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1298917003076	putative substrate binding site [chemical binding]; other site
1298917003077	putative ATP binding site [chemical binding]; other site
1298917003078	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1298917003079	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
1298917003080	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
1298917003081	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1298917003082	active site
1298917003083	substrate binding site [chemical binding]; other site
1298917003084	Mg2+ binding site [ion binding]; other site
1298917003085	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1298917003086	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1298917003087	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1298917003088	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1298917003089	active site
1298917003090	dimer interface [polypeptide binding]; other site
1298917003091	motif 1; other site
1298917003092	motif 2; other site
1298917003093	motif 3; other site
1298917003094	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1298917003095	anticodon binding site; other site
1298917003096	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1298917003097	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1298917003098	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1298917003099	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1298917003100	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1298917003101	23S rRNA binding site [nucleotide binding]; other site
1298917003102	L21 binding site [polypeptide binding]; other site
1298917003103	L13 binding site [polypeptide binding]; other site
1298917003104	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1298917003105	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1298917003106	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1298917003107	dimer interface [polypeptide binding]; other site
1298917003108	motif 1; other site
1298917003109	active site
1298917003110	motif 2; other site
1298917003111	motif 3; other site
1298917003112	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1298917003113	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1298917003114	putative tRNA-binding site [nucleotide binding]; other site
1298917003115	B3/4 domain; Region: B3_4; pfam03483
1298917003116	tRNA synthetase B5 domain; Region: B5; smart00874
1298917003117	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1298917003118	dimer interface [polypeptide binding]; other site
1298917003119	motif 1; other site
1298917003120	motif 3; other site
1298917003121	motif 2; other site
1298917003122	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1298917003123	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1298917003124	IHF dimer interface [polypeptide binding]; other site
1298917003125	IHF - DNA interface [nucleotide binding]; other site
1298917003126	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1298917003127	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1298917003128	ABC-ATPase subunit  interface; other site
1298917003129	dimer interface [polypeptide binding]; other site
1298917003130	putative PBP binding regions; other site
1298917003131	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1298917003132	catalytic residues [active]
1298917003133	dimer interface [polypeptide binding]; other site
1298917003134	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
1298917003135	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1298917003136	Walker A/P-loop; other site
1298917003137	ATP binding site [chemical binding]; other site
1298917003138	Q-loop/lid; other site
1298917003139	ABC transporter signature motif; other site
1298917003140	Walker B; other site
1298917003141	D-loop; other site
1298917003142	H-loop/switch region; other site
1298917003143	NlpC/P60 family; Region: NLPC_P60; pfam00877
1298917003144	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
1298917003145	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1298917003146	hypothetical protein; Validated; Region: PRK00029
1298917003147	hypothetical protein; Provisional; Region: PRK10183
1298917003148	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1298917003149	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1298917003150	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1298917003151	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1298917003152	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
1298917003153	Electron transfer flavoprotein domain; Region: ETF; smart00893
1298917003154	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1298917003155	Cupin domain; Region: Cupin_2; pfam07883
1298917003156	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1298917003157	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917003158	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
1298917003159	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1298917003160	active site
1298917003161	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1298917003162	Coenzyme A transferase; Region: CoA_trans; smart00882
1298917003163	Coenzyme A transferase; Region: CoA_trans; cl17247
1298917003164	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1298917003165	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1298917003166	active site
1298917003167	catalytic residue [active]
1298917003168	dimer interface [polypeptide binding]; other site
1298917003169	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
1298917003170	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1298917003171	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1298917003172	shikimate binding site; other site
1298917003173	NAD(P) binding site [chemical binding]; other site
1298917003174	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917003175	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1298917003176	putative substrate translocation pore; other site
1298917003177	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
1298917003178	putative inner membrane protein; Provisional; Region: PRK10983
1298917003179	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1298917003180	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1298917003181	FAD binding domain; Region: FAD_binding_4; pfam01565
1298917003182	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1298917003183	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1298917003184	CoenzymeA binding site [chemical binding]; other site
1298917003185	subunit interaction site [polypeptide binding]; other site
1298917003186	PHB binding site; other site
1298917003187	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1298917003188	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1298917003189	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1298917003190	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1298917003191	putative ABC transporter; Region: ycf24; CHL00085
1298917003192	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1298917003193	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1298917003194	Walker A/P-loop; other site
1298917003195	ATP binding site [chemical binding]; other site
1298917003196	Q-loop/lid; other site
1298917003197	ABC transporter signature motif; other site
1298917003198	Walker B; other site
1298917003199	D-loop; other site
1298917003200	H-loop/switch region; other site
1298917003201	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1298917003202	FeS assembly protein SufD; Region: sufD; TIGR01981
1298917003203	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1298917003204	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1298917003205	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1298917003206	catalytic residue [active]
1298917003207	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1298917003208	L,D-transpeptidase; Provisional; Region: PRK10190
1298917003209	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1298917003210	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1298917003211	murein lipoprotein; Provisional; Region: PRK15396
1298917003212	murein lipoprotein; Provisional; Region: PRK15396
1298917003213	pyruvate kinase; Provisional; Region: PRK09206
1298917003214	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1298917003215	domain interfaces; other site
1298917003216	active site
1298917003217	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1298917003218	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1298917003219	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1298917003220	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1298917003221	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1298917003222	substrate binding site [chemical binding]; other site
1298917003223	dimer interface [polypeptide binding]; other site
1298917003224	ATP binding site [chemical binding]; other site
1298917003225	tetrathionate reductase subunit A; Provisional; Region: PRK14991
1298917003226	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
1298917003227	putative [Fe4-S4] binding site [ion binding]; other site
1298917003228	putative molybdopterin cofactor binding site [chemical binding]; other site
1298917003229	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
1298917003230	putative molybdopterin cofactor binding site; other site
1298917003231	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1298917003232	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1298917003233	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1298917003234	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917003235	dimer interface [polypeptide binding]; other site
1298917003236	phosphorylation site [posttranslational modification]
1298917003237	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917003238	ATP binding site [chemical binding]; other site
1298917003239	Mg2+ binding site [ion binding]; other site
1298917003240	G-X-G motif; other site
1298917003241	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1298917003242	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917003243	active site
1298917003244	phosphorylation site [posttranslational modification]
1298917003245	intermolecular recognition site; other site
1298917003246	dimerization interface [polypeptide binding]; other site
1298917003247	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917003248	DNA binding residues [nucleotide binding]
1298917003249	dimerization interface [polypeptide binding]; other site
1298917003250	hypothetical protein; Provisional; Region: PRK10292
1298917003251	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1298917003252	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1298917003253	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
1298917003254	transcriptional regulator MirA; Provisional; Region: PRK15043
1298917003255	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1298917003256	DNA binding residues [nucleotide binding]
1298917003257	two component system sensor kinase SsrB; Provisional; Region: PRK15369
1298917003258	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917003259	active site
1298917003260	phosphorylation site [posttranslational modification]
1298917003261	intermolecular recognition site; other site
1298917003262	dimerization interface [polypeptide binding]; other site
1298917003263	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917003264	DNA binding residues [nucleotide binding]
1298917003265	dimerization interface [polypeptide binding]; other site
1298917003266	two component system sensor kinase SsrA; Provisional; Region: PRK15347
1298917003267	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917003268	dimerization interface [polypeptide binding]; other site
1298917003269	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917003270	dimer interface [polypeptide binding]; other site
1298917003271	phosphorylation site [posttranslational modification]
1298917003272	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917003273	ATP binding site [chemical binding]; other site
1298917003274	Mg2+ binding site [ion binding]; other site
1298917003275	G-X-G motif; other site
1298917003276	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917003277	active site
1298917003278	phosphorylation site [posttranslational modification]
1298917003279	intermolecular recognition site; other site
1298917003280	dimerization interface [polypeptide binding]; other site
1298917003281	pathogenicity island chaperone protein SpiC; Provisional; Region: PRK15368
1298917003282	outer membrane secretin SsaC; Provisional; Region: PRK15346
1298917003283	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1298917003284	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1298917003285	type III secretion system protein SsaD; Provisional; Region: PRK15367
1298917003286	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
1298917003287	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
1298917003288	type III secretion system chaperone SseA; Provisional; Region: PRK15365
1298917003289	EspA-like secreted protein; Region: EspA; cl04069
1298917003290	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
1298917003291	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
1298917003292	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
1298917003293	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
1298917003294	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
1298917003295	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1298917003296	TPR motif; other site
1298917003297	binding surface
1298917003298	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
1298917003299	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
1298917003300	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
1298917003301	type III secretion system protein SsaH; Provisional; Region: PRK15356
1298917003302	type III secretion system protein SsaI; Provisional; Region: PRK15355
1298917003303	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
1298917003304	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
1298917003305	type III secretion system protein SsaK; Provisional; Region: PRK15354
1298917003306	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
1298917003307	type III secretion system protein SsaL; Provisional; Region: PRK15345
1298917003308	HrpJ-like domain; Region: HrpJ; pfam07201
1298917003309	TyeA; Region: TyeA; cl07611
1298917003310	type III secretion system protein SsaM; Provisional; Region: PRK15353
1298917003311	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
1298917003312	FHIPEP family; Region: FHIPEP; pfam00771
1298917003313	type III secretion system ATPase SsaN; Validated; Region: PRK07594
1298917003314	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1298917003315	Walker A motif; other site
1298917003316	ATP binding site [chemical binding]; other site
1298917003317	Walker B motif; other site
1298917003318	type III secretion system protein SsaO; Provisional; Region: PRK15352
1298917003319	type III secretion system protein SsaP; Provisional; Region: PRK15351
1298917003320	type III secretion system protein SsaQ; Validated; Region: PRK08035
1298917003321	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1298917003322	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
1298917003323	type III secretion system protein SsaS; Provisional; Region: PRK15350
1298917003324	type III secretion system protein SsaT; Provisional; Region: PRK15349
1298917003325	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
1298917003326	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1298917003327	multidrug efflux protein; Reviewed; Region: PRK01766
1298917003328	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1298917003329	cation binding site [ion binding]; other site
1298917003330	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1298917003331	Lumazine binding domain; Region: Lum_binding; pfam00677
1298917003332	Lumazine binding domain; Region: Lum_binding; pfam00677
1298917003333	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1298917003334	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917003335	S-adenosylmethionine binding site [chemical binding]; other site
1298917003336	putative transporter; Provisional; Region: PRK11043
1298917003337	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917003338	putative substrate translocation pore; other site
1298917003339	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1298917003340	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917003341	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1298917003342	dimerization interface [polypeptide binding]; other site
1298917003343	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1298917003344	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917003345	DNA binding site [nucleotide binding]
1298917003346	domain linker motif; other site
1298917003347	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1298917003348	dimerization interface [polypeptide binding]; other site
1298917003349	ligand binding site [chemical binding]; other site
1298917003350	superoxide dismutase; Provisional; Region: PRK10543
1298917003351	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1298917003352	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1298917003353	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1298917003354	NlpC/P60 family; Region: NLPC_P60; pfam00877
1298917003355	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1298917003356	putative GSH binding site [chemical binding]; other site
1298917003357	catalytic residues [active]
1298917003358	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1298917003359	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1298917003360	dimer interface [polypeptide binding]; other site
1298917003361	catalytic site [active]
1298917003362	putative active site [active]
1298917003363	putative substrate binding site [chemical binding]; other site
1298917003364	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1298917003365	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1298917003366	dimer interface [polypeptide binding]; other site
1298917003367	active site
1298917003368	metal binding site [ion binding]; metal-binding site
1298917003369	glutathione binding site [chemical binding]; other site
1298917003370	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1298917003371	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1298917003372	FMN binding site [chemical binding]; other site
1298917003373	active site
1298917003374	substrate binding site [chemical binding]; other site
1298917003375	catalytic residue [active]
1298917003376	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1298917003377	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917003378	Predicted Fe-S protein [General function prediction only]; Region: COG3313
1298917003379	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1298917003380	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1298917003381	active site
1298917003382	catalytic tetrad [active]
1298917003383	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1298917003384	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1298917003385	E-class dimer interface [polypeptide binding]; other site
1298917003386	P-class dimer interface [polypeptide binding]; other site
1298917003387	active site
1298917003388	Cu2+ binding site [ion binding]; other site
1298917003389	Zn2+ binding site [ion binding]; other site
1298917003390	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1298917003391	transcriptional regulator SlyA; Provisional; Region: PRK03573
1298917003392	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1298917003393	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1298917003394	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1298917003395	lysozyme inhibitor; Provisional; Region: PRK11372
1298917003396	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1298917003397	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1298917003398	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1298917003399	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1298917003400	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1298917003401	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1298917003402	active site
1298917003403	HIGH motif; other site
1298917003404	dimer interface [polypeptide binding]; other site
1298917003405	KMSKS motif; other site
1298917003406	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1298917003407	RNA binding surface [nucleotide binding]; other site
1298917003408	pyridoxamine kinase; Validated; Region: PRK05756
1298917003409	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1298917003410	dimer interface [polypeptide binding]; other site
1298917003411	pyridoxal binding site [chemical binding]; other site
1298917003412	ATP binding site [chemical binding]; other site
1298917003413	glutathionine S-transferase; Provisional; Region: PRK10542
1298917003414	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1298917003415	C-terminal domain interface [polypeptide binding]; other site
1298917003416	GSH binding site (G-site) [chemical binding]; other site
1298917003417	dimer interface [polypeptide binding]; other site
1298917003418	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1298917003419	dimer interface [polypeptide binding]; other site
1298917003420	substrate binding pocket (H-site) [chemical binding]; other site
1298917003421	N-terminal domain interface [polypeptide binding]; other site
1298917003422	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1298917003423	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917003424	putative substrate translocation pore; other site
1298917003425	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917003426	endonuclease III; Provisional; Region: PRK10702
1298917003427	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1298917003428	minor groove reading motif; other site
1298917003429	helix-hairpin-helix signature motif; other site
1298917003430	substrate binding pocket [chemical binding]; other site
1298917003431	active site
1298917003432	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1298917003433	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1298917003434	electron transport complex protein RnfG; Validated; Region: PRK01908
1298917003435	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1298917003436	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1298917003437	SLBB domain; Region: SLBB; pfam10531
1298917003438	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1298917003439	electron transport complex protein RnfB; Provisional; Region: PRK05113
1298917003440	Putative Fe-S cluster; Region: FeS; cl17515
1298917003441	4Fe-4S binding domain; Region: Fer4; pfam00037
1298917003442	electron transport complex protein RsxA; Provisional; Region: PRK05151
1298917003443	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1298917003444	putative oxidoreductase; Provisional; Region: PRK11579
1298917003445	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1298917003446	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1298917003447	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1298917003448	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1298917003449	active site
1298917003450	purine riboside binding site [chemical binding]; other site
1298917003451	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
1298917003452	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1298917003453	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1298917003454	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1298917003455	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1298917003456	Class II fumarases; Region: Fumarase_classII; cd01362
1298917003457	active site
1298917003458	tetramer interface [polypeptide binding]; other site
1298917003459	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1298917003460	sensor protein RstB; Provisional; Region: PRK10604
1298917003461	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917003462	dimerization interface [polypeptide binding]; other site
1298917003463	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917003464	dimer interface [polypeptide binding]; other site
1298917003465	phosphorylation site [posttranslational modification]
1298917003466	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917003467	ATP binding site [chemical binding]; other site
1298917003468	Mg2+ binding site [ion binding]; other site
1298917003469	G-X-G motif; other site
1298917003470	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1298917003471	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1298917003472	active site
1298917003473	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1298917003474	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1298917003475	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1298917003476	trimer interface [polypeptide binding]; other site
1298917003477	eyelet of channel; other site
1298917003478	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1298917003479	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917003480	active site
1298917003481	phosphorylation site [posttranslational modification]
1298917003482	intermolecular recognition site; other site
1298917003483	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917003484	DNA binding site [nucleotide binding]
1298917003485	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1298917003486	Spore germination protein; Region: Spore_permease; cl17796
1298917003487	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1298917003488	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1298917003489	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1298917003490	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1298917003491	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1298917003492	ligand binding site [chemical binding]; other site
1298917003493	homodimer interface [polypeptide binding]; other site
1298917003494	NAD(P) binding site [chemical binding]; other site
1298917003495	trimer interface B [polypeptide binding]; other site
1298917003496	trimer interface A [polypeptide binding]; other site
1298917003497	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1298917003498	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1298917003499	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1298917003500	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1298917003501	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1298917003502	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1298917003503	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1298917003504	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917003505	putative substrate translocation pore; other site
1298917003506	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1298917003507	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1298917003508	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917003509	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1298917003510	dimerization interface [polypeptide binding]; other site
1298917003511	substrate binding pocket [chemical binding]; other site
1298917003512	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1298917003513	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1298917003514	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1298917003515	nucleotide binding site [chemical binding]; other site
1298917003516	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1298917003517	AAA domain; Region: AAA_26; pfam13500
1298917003518	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917003519	dimer interface [polypeptide binding]; other site
1298917003520	conserved gate region; other site
1298917003521	ABC-ATPase subunit interface; other site
1298917003522	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1298917003523	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1298917003524	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1298917003525	4Fe-4S binding domain; Region: Fer4; pfam00037
1298917003526	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1298917003527	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1298917003528	putative [Fe4-S4] binding site [ion binding]; other site
1298917003529	putative molybdopterin cofactor binding site [chemical binding]; other site
1298917003530	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1298917003531	putative molybdopterin cofactor binding site; other site
1298917003532	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1298917003533	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1298917003534	putative [Fe4-S4] binding site [ion binding]; other site
1298917003535	putative molybdopterin cofactor binding site [chemical binding]; other site
1298917003536	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1298917003537	putative molybdopterin cofactor binding site; other site
1298917003538	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1298917003539	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
1298917003540	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1298917003541	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917003542	Coenzyme A binding pocket [chemical binding]; other site
1298917003543	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1298917003544	hypothetical protein; Provisional; Region: PRK13659
1298917003545	hypothetical protein; Provisional; Region: PRK02237
1298917003546	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1298917003547	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1298917003548	putative active site pocket [active]
1298917003549	putative metal binding site [ion binding]; other site
1298917003550	putative oxidoreductase; Provisional; Region: PRK10083
1298917003551	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1298917003552	putative NAD(P) binding site [chemical binding]; other site
1298917003553	catalytic Zn binding site [ion binding]; other site
1298917003554	structural Zn binding site [ion binding]; other site
1298917003555	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917003556	metabolite-proton symporter; Region: 2A0106; TIGR00883
1298917003557	putative substrate translocation pore; other site
1298917003558	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1298917003559	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1298917003560	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1298917003561	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
1298917003562	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1298917003563	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917003564	DNA-binding site [nucleotide binding]; DNA binding site
1298917003565	FCD domain; Region: FCD; pfam07729
1298917003566	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1298917003567	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1298917003568	active site
1298917003569	Zn binding site [ion binding]; other site
1298917003570	General stress protein [General function prediction only]; Region: GsiB; COG3729
1298917003571	hypothetical protein; Validated; Region: PRK03657
1298917003572	hypothetical protein; Provisional; Region: PRK10053
1298917003573	putative transporter; Provisional; Region: PRK10054
1298917003574	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917003575	putative substrate translocation pore; other site
1298917003576	MarB protein; Region: MarB; pfam13999
1298917003577	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
1298917003578	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917003579	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917003580	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
1298917003581	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1298917003582	inner membrane protein; Provisional; Region: PRK10995
1298917003583	putative arabinose transporter; Provisional; Region: PRK03545
1298917003584	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917003585	putative substrate translocation pore; other site
1298917003586	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917003587	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917003588	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1298917003589	putative dimerization interface [polypeptide binding]; other site
1298917003590	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1298917003591	glutaminase; Provisional; Region: PRK00971
1298917003592	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1298917003593	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1298917003594	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1298917003595	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1298917003596	trimer interface [polypeptide binding]; other site
1298917003597	eyelet of channel; other site
1298917003598	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1298917003599	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1298917003600	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
1298917003601	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1298917003602	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1298917003603	Rubredoxin [Energy production and conversion]; Region: COG1773
1298917003604	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1298917003605	iron binding site [ion binding]; other site
1298917003606	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1298917003607	HupF/HypC family; Region: HupF_HypC; cl00394
1298917003608	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1298917003609	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1298917003610	putative substrate-binding site; other site
1298917003611	nickel binding site [ion binding]; other site
1298917003612	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
1298917003613	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1298917003614	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1298917003615	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
1298917003616	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1298917003617	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1298917003618	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917003619	DNA-binding site [nucleotide binding]; DNA binding site
1298917003620	FCD domain; Region: FCD; pfam07729
1298917003621	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1298917003622	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1298917003623	putative NAD(P) binding site [chemical binding]; other site
1298917003624	catalytic Zn binding site [ion binding]; other site
1298917003625	structural Zn binding site [ion binding]; other site
1298917003626	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
1298917003627	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1298917003628	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917003629	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1298917003630	putative substrate translocation pore; other site
1298917003631	hypothetical protein; Provisional; Region: PRK06184
1298917003632	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1298917003633	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1298917003634	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1298917003635	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1298917003636	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1298917003637	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917003638	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917003639	homodimer interface [polypeptide binding]; other site
1298917003640	catalytic residue [active]
1298917003641	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1298917003642	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1298917003643	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1298917003644	active site
1298917003645	catalytic site [active]
1298917003646	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
1298917003647	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1298917003648	active site
1298917003649	catalytic site [active]
1298917003650	acid-resistance protein; Provisional; Region: hdeB; PRK11566
1298917003651	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1298917003652	biofilm-dependent modulation protein; Provisional; Region: PRK11436
1298917003653	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
1298917003654	malate dehydrogenase; Provisional; Region: PRK13529
1298917003655	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1298917003656	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1298917003657	NAD(P) binding site [chemical binding]; other site
1298917003658	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1298917003659	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1298917003660	NAD binding site [chemical binding]; other site
1298917003661	substrate binding site [chemical binding]; other site
1298917003662	catalytic Zn binding site [ion binding]; other site
1298917003663	tetramer interface [polypeptide binding]; other site
1298917003664	structural Zn binding site [ion binding]; other site
1298917003665	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1298917003666	tellurite resistance protein TehB; Provisional; Region: PRK11207
1298917003667	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917003668	S-adenosylmethionine binding site [chemical binding]; other site
1298917003669	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1298917003670	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1298917003671	gating phenylalanine in ion channel; other site
1298917003672	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1298917003673	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1298917003674	putative trimer interface [polypeptide binding]; other site
1298917003675	putative CoA binding site [chemical binding]; other site
1298917003676	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1298917003677	putative trimer interface [polypeptide binding]; other site
1298917003678	putative CoA binding site [chemical binding]; other site
1298917003679	ribosomal-protein-L7/L12-serine acetyltransferase; Provisional; Region: PRK10151
1298917003680	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1298917003681	Coenzyme A binding pocket [chemical binding]; other site
1298917003682	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1298917003683	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1298917003684	oligomer interface [polypeptide binding]; other site
1298917003685	active site
1298917003686	metal binding site [ion binding]; metal-binding site
1298917003687	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1298917003688	active site
1298917003689	P-loop; other site
1298917003690	phosphorylation site [posttranslational modification]
1298917003691	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1298917003692	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
1298917003693	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
1298917003694	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1298917003695	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1298917003696	substrate binding site [chemical binding]; other site
1298917003697	hexamer interface [polypeptide binding]; other site
1298917003698	metal binding site [ion binding]; metal-binding site
1298917003699	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1298917003700	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1298917003701	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917003702	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1298917003703	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917003704	Coenzyme A binding pocket [chemical binding]; other site
1298917003705	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1298917003706	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1298917003707	metal binding site [ion binding]; metal-binding site
1298917003708	substrate binding pocket [chemical binding]; other site
1298917003709	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
1298917003710	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1298917003711	NADP binding site [chemical binding]; other site
1298917003712	homodimer interface [polypeptide binding]; other site
1298917003713	active site
1298917003714	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917003715	D-galactonate transporter; Region: 2A0114; TIGR00893
1298917003716	putative substrate translocation pore; other site
1298917003717	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1298917003718	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1298917003719	putative NAD(P) binding site [chemical binding]; other site
1298917003720	catalytic Zn binding site [ion binding]; other site
1298917003721	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1298917003722	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917003723	DNA-binding site [nucleotide binding]; DNA binding site
1298917003724	FCD domain; Region: FCD; pfam07729
1298917003725	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1298917003726	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1298917003727	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1298917003728	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1298917003729	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1298917003730	substrate binding pocket [chemical binding]; other site
1298917003731	catalytic triad [active]
1298917003732	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1298917003733	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1298917003734	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1298917003735	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917003736	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1298917003737	dimerization interface [polypeptide binding]; other site
1298917003738	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1298917003739	dimer interface [polypeptide binding]; other site
1298917003740	ligand binding site [chemical binding]; other site
1298917003741	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1298917003742	HAMP domain; Region: HAMP; pfam00672
1298917003743	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1298917003744	dimer interface [polypeptide binding]; other site
1298917003745	putative CheW interface [polypeptide binding]; other site
1298917003746	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1298917003747	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1298917003748	substrate binding site [chemical binding]; other site
1298917003749	catalytic Zn binding site [ion binding]; other site
1298917003750	NAD binding site [chemical binding]; other site
1298917003751	structural Zn binding site [ion binding]; other site
1298917003752	dimer interface [polypeptide binding]; other site
1298917003753	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1298917003754	putative metal binding site [ion binding]; other site
1298917003755	putative homodimer interface [polypeptide binding]; other site
1298917003756	putative homotetramer interface [polypeptide binding]; other site
1298917003757	putative homodimer-homodimer interface [polypeptide binding]; other site
1298917003758	putative allosteric switch controlling residues; other site
1298917003759	Sif protein; Region: Sif; cl11505
1298917003760	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1298917003761	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
1298917003762	active site
1298917003763	catalytic triad [active]
1298917003764	oxyanion hole [active]
1298917003765	Predicted membrane protein [Function unknown]; Region: COG3326
1298917003766	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917003767	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1298917003768	substrate binding pocket [chemical binding]; other site
1298917003769	membrane-bound complex binding site; other site
1298917003770	hinge residues; other site
1298917003771	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1298917003772	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917003773	dimer interface [polypeptide binding]; other site
1298917003774	conserved gate region; other site
1298917003775	putative PBP binding loops; other site
1298917003776	ABC-ATPase subunit interface; other site
1298917003777	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1298917003778	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917003779	Walker A/P-loop; other site
1298917003780	ATP binding site [chemical binding]; other site
1298917003781	Q-loop/lid; other site
1298917003782	ABC transporter signature motif; other site
1298917003783	Walker B; other site
1298917003784	D-loop; other site
1298917003785	H-loop/switch region; other site
1298917003786	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1298917003787	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917003788	dimer interface [polypeptide binding]; other site
1298917003789	conserved gate region; other site
1298917003790	putative PBP binding loops; other site
1298917003791	ABC-ATPase subunit interface; other site
1298917003792	Predicted membrane protein [Function unknown]; Region: COG5305
1298917003793	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917003794	S-adenosylmethionine binding site [chemical binding]; other site
1298917003795	cytochrome b561; Provisional; Region: PRK11513
1298917003796	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1298917003797	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1298917003798	ATP binding site [chemical binding]; other site
1298917003799	putative Mg++ binding site [ion binding]; other site
1298917003800	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917003801	nucleotide binding region [chemical binding]; other site
1298917003802	ATP-binding site [chemical binding]; other site
1298917003803	Helicase associated domain (HA2); Region: HA2; pfam04408
1298917003804	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1298917003805	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1298917003806	azoreductase; Reviewed; Region: PRK00170
1298917003807	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1298917003808	Glutathione-dependent formaldehyde-activating enzyme; Region: GFA; cl01553
1298917003809	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1298917003810	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1298917003811	hypothetical protein; Provisional; Region: PRK10695
1298917003812	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1298917003813	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1298917003814	putative ligand binding site [chemical binding]; other site
1298917003815	putative NAD binding site [chemical binding]; other site
1298917003816	catalytic site [active]
1298917003817	heat-inducible protein; Provisional; Region: PRK10449
1298917003818	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1298917003819	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1298917003820	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1298917003821	Ligand Binding Site [chemical binding]; other site
1298917003822	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1298917003823	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1298917003824	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1298917003825	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1298917003826	Ligand Binding Site [chemical binding]; other site
1298917003827	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1298917003828	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1298917003829	ATP binding site [chemical binding]; other site
1298917003830	Mg++ binding site [ion binding]; other site
1298917003831	motif III; other site
1298917003832	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917003833	nucleotide binding region [chemical binding]; other site
1298917003834	ATP-binding site [chemical binding]; other site
1298917003835	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1298917003836	putative RNA binding site [nucleotide binding]; other site
1298917003837	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1298917003838	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1298917003839	Cl binding site [ion binding]; other site
1298917003840	oligomer interface [polypeptide binding]; other site
1298917003841	HAMP domain; Region: HAMP; pfam00672
1298917003842	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1298917003843	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1298917003844	dimer interface [polypeptide binding]; other site
1298917003845	putative CheW interface [polypeptide binding]; other site
1298917003846	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1298917003847	Smr domain; Region: Smr; pfam01713
1298917003848	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1298917003849	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1298917003850	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1298917003851	DNA binding site [nucleotide binding]
1298917003852	active site
1298917003853	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1298917003854	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1298917003855	ligand binding site [chemical binding]; other site
1298917003856	flexible hinge region; other site
1298917003857	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1298917003858	putative switch regulator; other site
1298917003859	non-specific DNA interactions [nucleotide binding]; other site
1298917003860	DNA binding site [nucleotide binding]
1298917003861	sequence specific DNA binding site [nucleotide binding]; other site
1298917003862	putative cAMP binding site [chemical binding]; other site
1298917003863	universal stress protein UspE; Provisional; Region: PRK11175
1298917003864	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1298917003865	Ligand Binding Site [chemical binding]; other site
1298917003866	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1298917003867	Ligand Binding Site [chemical binding]; other site
1298917003868	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1298917003869	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1298917003870	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1298917003871	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1298917003872	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1298917003873	active site
1298917003874	catalytic tetrad [active]
1298917003875	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917003876	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917003877	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1298917003878	putative effector binding pocket; other site
1298917003879	putative dimerization interface [polypeptide binding]; other site
1298917003880	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1298917003881	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1298917003882	peptide binding site [polypeptide binding]; other site
1298917003883	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1298917003884	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1298917003885	active site
1298917003886	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1298917003887	dimer interface [polypeptide binding]; other site
1298917003888	catalytic triad [active]
1298917003889	peroxidatic and resolving cysteines [active]
1298917003890	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1298917003891	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1298917003892	putative aromatic amino acid binding site; other site
1298917003893	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917003894	Walker A motif; other site
1298917003895	ATP binding site [chemical binding]; other site
1298917003896	Walker B motif; other site
1298917003897	arginine finger; other site
1298917003898	hypothetical protein; Provisional; Region: PRK05415
1298917003899	TIGR01620 family protein; Region: hyp_HI0043
1298917003900	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1298917003901	active site residue [active]
1298917003902	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1298917003903	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1298917003904	phage shock protein C; Region: phageshock_pspC; TIGR02978
1298917003905	phage shock protein B; Provisional; Region: pspB; PRK09458
1298917003906	phage shock protein PspA; Provisional; Region: PRK10698
1298917003907	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1298917003908	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1298917003909	peptide binding site [polypeptide binding]; other site
1298917003910	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1298917003911	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917003912	dimer interface [polypeptide binding]; other site
1298917003913	conserved gate region; other site
1298917003914	putative PBP binding loops; other site
1298917003915	ABC-ATPase subunit interface; other site
1298917003916	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1298917003917	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1298917003918	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917003919	dimer interface [polypeptide binding]; other site
1298917003920	conserved gate region; other site
1298917003921	putative PBP binding loops; other site
1298917003922	ABC-ATPase subunit interface; other site
1298917003923	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1298917003924	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1298917003925	Walker A/P-loop; other site
1298917003926	ATP binding site [chemical binding]; other site
1298917003927	Q-loop/lid; other site
1298917003928	ABC transporter signature motif; other site
1298917003929	Walker B; other site
1298917003930	D-loop; other site
1298917003931	H-loop/switch region; other site
1298917003932	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1298917003933	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1298917003934	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1298917003935	Walker A/P-loop; other site
1298917003936	ATP binding site [chemical binding]; other site
1298917003937	Q-loop/lid; other site
1298917003938	ABC transporter signature motif; other site
1298917003939	Walker B; other site
1298917003940	D-loop; other site
1298917003941	H-loop/switch region; other site
1298917003942	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1298917003943	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1298917003944	NAD binding site [chemical binding]; other site
1298917003945	homotetramer interface [polypeptide binding]; other site
1298917003946	homodimer interface [polypeptide binding]; other site
1298917003947	substrate binding site [chemical binding]; other site
1298917003948	active site
1298917003949	exoribonuclease II; Provisional; Region: PRK05054
1298917003950	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1298917003951	RNB domain; Region: RNB; pfam00773
1298917003952	S1 RNA binding domain; Region: S1; pfam00575
1298917003953	RNase II stability modulator; Provisional; Region: PRK10060
1298917003954	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1298917003955	putative active site [active]
1298917003956	heme pocket [chemical binding]; other site
1298917003957	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1298917003958	metal binding site [ion binding]; metal-binding site
1298917003959	active site
1298917003960	I-site; other site
1298917003961	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917003962	hypothetical protein; Provisional; Region: PRK13658
1298917003963	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1298917003964	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1298917003965	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917003966	lipoprotein; Provisional; Region: PRK10540
1298917003967	translation initiation factor Sui1; Validated; Region: PRK06824
1298917003968	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1298917003969	putative rRNA binding site [nucleotide binding]; other site
1298917003970	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1298917003971	active site
1298917003972	dimer interface [polypeptide binding]; other site
1298917003973	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1298917003974	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1298917003975	binding surface
1298917003976	TPR motif; other site
1298917003977	Predicted membrane protein [Function unknown]; Region: COG3771
1298917003978	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1298917003979	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1298917003980	active site
1298917003981	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1298917003982	dimerization interface [polypeptide binding]; other site
1298917003983	active site
1298917003984	aconitate hydratase; Validated; Region: PRK09277
1298917003985	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1298917003986	substrate binding site [chemical binding]; other site
1298917003987	ligand binding site [chemical binding]; other site
1298917003988	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1298917003989	substrate binding site [chemical binding]; other site
1298917003990	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1298917003991	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917003992	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1298917003993	substrate binding site [chemical binding]; other site
1298917003994	putative dimerization interface [polypeptide binding]; other site
1298917003995	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1298917003996	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1298917003997	active site
1298917003998	interdomain interaction site; other site
1298917003999	putative metal-binding site [ion binding]; other site
1298917004000	nucleotide binding site [chemical binding]; other site
1298917004001	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1298917004002	domain I; other site
1298917004003	DNA binding groove [nucleotide binding]
1298917004004	phosphate binding site [ion binding]; other site
1298917004005	domain II; other site
1298917004006	domain III; other site
1298917004007	nucleotide binding site [chemical binding]; other site
1298917004008	catalytic site [active]
1298917004009	domain IV; other site
1298917004010	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1298917004011	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1298917004012	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1298917004013	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1298917004014	hypothetical protein; Provisional; Region: PRK11037
1298917004015	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1298917004016	putative inner membrane peptidase; Provisional; Region: PRK11778
1298917004017	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1298917004018	tandem repeat interface [polypeptide binding]; other site
1298917004019	oligomer interface [polypeptide binding]; other site
1298917004020	active site residues [active]
1298917004021	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1298917004022	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1298917004023	NADP binding site [chemical binding]; other site
1298917004024	homodimer interface [polypeptide binding]; other site
1298917004025	active site
1298917004026	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1298917004027	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
1298917004028	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1298917004029	homodimer interface [polypeptide binding]; other site
1298917004030	Walker A motif; other site
1298917004031	ATP binding site [chemical binding]; other site
1298917004032	hydroxycobalamin binding site [chemical binding]; other site
1298917004033	Walker B motif; other site
1298917004034	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1298917004035	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1298917004036	RNA binding surface [nucleotide binding]; other site
1298917004037	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1298917004038	probable active site [active]
1298917004039	hypothetical protein; Provisional; Region: PRK11630
1298917004040	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1298917004041	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1298917004042	active site
1298917004043	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1298917004044	anthranilate synthase component I; Provisional; Region: PRK13564
1298917004045	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1298917004046	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1298917004047	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
1298917004048	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1298917004049	glutamine binding [chemical binding]; other site
1298917004050	catalytic triad [active]
1298917004051	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1298917004052	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1298917004053	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1298917004054	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1298917004055	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917004056	catalytic residue [active]
1298917004057	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1298917004058	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1298917004059	substrate binding site [chemical binding]; other site
1298917004060	active site
1298917004061	catalytic residues [active]
1298917004062	heterodimer interface [polypeptide binding]; other site
1298917004063	General stress protein [General function prediction only]; Region: GsiB; COG3729
1298917004064	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
1298917004065	dimerization interface [polypeptide binding]; other site
1298917004066	metal binding site [ion binding]; metal-binding site
1298917004067	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1298917004068	dinuclear metal binding motif [ion binding]; other site
1298917004069	outer membrane protein W; Provisional; Region: PRK10959
1298917004070	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1298917004071	hypothetical protein; Provisional; Region: PRK02868
1298917004072	intracellular septation protein A; Reviewed; Region: PRK00259
1298917004073	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1298917004074	transport protein TonB; Provisional; Region: PRK10819
1298917004075	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1298917004076	YCII-related domain; Region: YCII; cl00999
1298917004077	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1298917004078	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1298917004079	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1298917004080	putative active site [active]
1298917004081	catalytic site [active]
1298917004082	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1298917004083	putative active site [active]
1298917004084	catalytic site [active]
1298917004085	dsDNA-mimic protein; Reviewed; Region: PRK05094
1298917004086	Ion transport protein; Region: Ion_trans; pfam00520
1298917004087	Ion channel; Region: Ion_trans_2; pfam07885
1298917004088	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1298917004089	Double zinc ribbon; Region: DZR; pfam12773
1298917004090	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1298917004091	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1298917004092	Walker A/P-loop; other site
1298917004093	ATP binding site [chemical binding]; other site
1298917004094	Q-loop/lid; other site
1298917004095	ABC transporter signature motif; other site
1298917004096	Walker B; other site
1298917004097	D-loop; other site
1298917004098	H-loop/switch region; other site
1298917004099	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1298917004100	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1298917004101	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1298917004102	Walker A/P-loop; other site
1298917004103	ATP binding site [chemical binding]; other site
1298917004104	Q-loop/lid; other site
1298917004105	ABC transporter signature motif; other site
1298917004106	Walker B; other site
1298917004107	D-loop; other site
1298917004108	H-loop/switch region; other site
1298917004109	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1298917004110	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1298917004111	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1298917004112	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917004113	dimer interface [polypeptide binding]; other site
1298917004114	conserved gate region; other site
1298917004115	ABC-ATPase subunit interface; other site
1298917004116	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1298917004117	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917004118	dimer interface [polypeptide binding]; other site
1298917004119	conserved gate region; other site
1298917004120	putative PBP binding loops; other site
1298917004121	ABC-ATPase subunit interface; other site
1298917004122	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1298917004123	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1298917004124	peptide binding site [polypeptide binding]; other site
1298917004125	hypothetical protein; Provisional; Region: PRK11111
1298917004126	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1298917004127	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1298917004128	putative catalytic cysteine [active]
1298917004129	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1298917004130	putative active site [active]
1298917004131	metal binding site [ion binding]; metal-binding site
1298917004132	thymidine kinase; Provisional; Region: PRK04296
1298917004133	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1298917004134	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1298917004135	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1298917004136	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1298917004137	active site
1298917004138	tetramer interface; other site
1298917004139	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917004140	active site
1298917004141	response regulator of RpoS; Provisional; Region: PRK10693
1298917004142	phosphorylation site [posttranslational modification]
1298917004143	intermolecular recognition site; other site
1298917004144	dimerization interface [polypeptide binding]; other site
1298917004145	hypothetical protein; Provisional; Region: PRK10279
1298917004146	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1298917004147	active site
1298917004148	nucleophile elbow; other site
1298917004149	hypothetical protein; Provisional; Region: PRK01617
1298917004150	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1298917004151	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1298917004152	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1298917004153	putative active site [active]
1298917004154	putative substrate binding site [chemical binding]; other site
1298917004155	putative cosubstrate binding site; other site
1298917004156	catalytic site [active]
1298917004157	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1298917004158	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1298917004159	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1298917004160	4Fe-4S binding domain; Region: Fer4; cl02805
1298917004161	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1298917004162	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1298917004163	[4Fe-4S] binding site [ion binding]; other site
1298917004164	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1298917004165	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1298917004166	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1298917004167	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1298917004168	molybdopterin cofactor binding site; other site
1298917004169	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1298917004170	transcriptional regulator NarL; Provisional; Region: PRK10651
1298917004171	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917004172	active site
1298917004173	phosphorylation site [posttranslational modification]
1298917004174	intermolecular recognition site; other site
1298917004175	dimerization interface [polypeptide binding]; other site
1298917004176	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917004177	DNA binding residues [nucleotide binding]
1298917004178	dimerization interface [polypeptide binding]; other site
1298917004179	putative invasin; Provisional; Region: PRK10177
1298917004180	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1298917004181	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1298917004182	cation transport regulator; Reviewed; Region: chaB; PRK09582
1298917004183	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
1298917004184	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1298917004185	hypothetical protein; Provisional; Region: PRK10941
1298917004186	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1298917004187	hypothetical protein; Provisional; Region: PRK10278
1298917004188	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1298917004189	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917004190	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1298917004191	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1298917004192	RF-1 domain; Region: RF-1; pfam00472
1298917004193	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1298917004194	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1298917004195	tRNA; other site
1298917004196	putative tRNA binding site [nucleotide binding]; other site
1298917004197	putative NADP binding site [chemical binding]; other site
1298917004198	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1298917004199	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
1298917004200	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1298917004201	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1298917004202	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1298917004203	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1298917004204	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1298917004205	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1298917004206	active site
1298917004207	putative transporter; Provisional; Region: PRK11660
1298917004208	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1298917004209	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1298917004210	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1298917004211	hypothetical protein; Provisional; Region: PRK10692
1298917004212	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1298917004213	putative active site [active]
1298917004214	catalytic residue [active]
1298917004215	GTP-binding protein YchF; Reviewed; Region: PRK09601
1298917004216	YchF GTPase; Region: YchF; cd01900
1298917004217	G1 box; other site
1298917004218	GTP/Mg2+ binding site [chemical binding]; other site
1298917004219	Switch I region; other site
1298917004220	G2 box; other site
1298917004221	Switch II region; other site
1298917004222	G3 box; other site
1298917004223	G4 box; other site
1298917004224	G5 box; other site
1298917004225	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1298917004226	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1298917004227	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1298917004228	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1298917004229	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1298917004230	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1298917004231	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
1298917004232	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1298917004233	putative substrate-binding site; other site
1298917004234	nickel binding site [ion binding]; other site
1298917004235	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
1298917004236	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1298917004237	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
1298917004238	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1298917004239	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
1298917004240	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1298917004241	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1298917004242	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1298917004243	NAD(P) binding site [chemical binding]; other site
1298917004244	trehalase; Provisional; Region: treA; PRK13271
1298917004245	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1298917004246	hypothetical protein; Provisional; Region: PRK10457
1298917004247	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1298917004248	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1298917004249	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1298917004250	catalytic residue [active]
1298917004251	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1298917004252	dimer interface [polypeptide binding]; other site
1298917004253	catalytic triad [active]
1298917004254	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1298917004255	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1298917004256	TrkA-C domain; Region: TrkA_C; pfam02080
1298917004257	Transporter associated domain; Region: CorC_HlyC; smart01091
1298917004258	alanine racemase; Reviewed; Region: dadX; PRK03646
1298917004259	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1298917004260	active site
1298917004261	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1298917004262	substrate binding site [chemical binding]; other site
1298917004263	catalytic residues [active]
1298917004264	dimer interface [polypeptide binding]; other site
1298917004265	SpoVR family protein; Provisional; Region: PRK11767
1298917004266	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1298917004267	fatty acid metabolism regulator; Provisional; Region: PRK04984
1298917004268	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917004269	DNA-binding site [nucleotide binding]; DNA binding site
1298917004270	FadR C-terminal domain; Region: FadR_C; pfam07840
1298917004271	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1298917004272	transmembrane helices; other site
1298917004273	disulfide bond formation protein B; Provisional; Region: PRK01749
1298917004274	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1298917004275	GnsA/GnsB family; Region: GnsAB; pfam08178
1298917004276	hypothetical protein; Provisional; Region: PRK05170
1298917004277	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1298917004278	hypothetical protein; Provisional; Region: PRK10691
1298917004279	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1298917004280	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1298917004281	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1298917004282	cell division inhibitor MinD; Provisional; Region: PRK10818
1298917004283	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1298917004284	Switch I; other site
1298917004285	Switch II; other site
1298917004286	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1298917004287	ribonuclease D; Provisional; Region: PRK10829
1298917004288	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1298917004289	catalytic site [active]
1298917004290	putative active site [active]
1298917004291	putative substrate binding site [chemical binding]; other site
1298917004292	HRDC domain; Region: HRDC; cl02578
1298917004293	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1298917004294	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1298917004295	acyl-activating enzyme (AAE) consensus motif; other site
1298917004296	putative AMP binding site [chemical binding]; other site
1298917004297	putative active site [active]
1298917004298	putative CoA binding site [chemical binding]; other site
1298917004299	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
1298917004300	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1298917004301	Glycoprotease family; Region: Peptidase_M22; pfam00814
1298917004302	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1298917004303	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1298917004304	DEAD_2; Region: DEAD_2; pfam06733
1298917004305	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1298917004306	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1298917004307	homotrimer interaction site [polypeptide binding]; other site
1298917004308	putative active site [active]
1298917004309	hypothetical protein; Provisional; Region: PRK05114
1298917004310	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1298917004311	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1298917004312	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
1298917004313	L-serine deaminase; Provisional; Region: PRK15023
1298917004314	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1298917004315	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1298917004316	phage resistance protein; Provisional; Region: PRK10551
1298917004317	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1298917004318	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917004319	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1298917004320	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1298917004321	active pocket/dimerization site; other site
1298917004322	active site
1298917004323	phosphorylation site [posttranslational modification]
1298917004324	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1298917004325	active site
1298917004326	phosphorylation site [posttranslational modification]
1298917004327	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1298917004328	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1298917004329	Protein of unknown function (DUF986); Region: DUF986; cl01983
1298917004330	Protein of unknown function (DUF986); Region: DUF986; cl01983
1298917004331	hypothetical protein; Provisional; Region: PRK11469
1298917004332	Domain of unknown function DUF; Region: DUF204; pfam02659
1298917004333	Domain of unknown function DUF; Region: DUF204; pfam02659
1298917004334	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1298917004335	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917004336	S-adenosylmethionine binding site [chemical binding]; other site
1298917004337	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1298917004338	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1298917004339	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1298917004340	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1298917004341	DNA-binding site [nucleotide binding]; DNA binding site
1298917004342	RNA-binding motif; other site
1298917004343	YebO-like protein; Region: YebO; pfam13974
1298917004344	PhoPQ regulatory protein; Provisional; Region: PRK10299
1298917004345	YobH-like protein; Region: YobH; pfam13996
1298917004346	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1298917004347	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1298917004348	dimerization interface [polypeptide binding]; other site
1298917004349	putative Zn2+ binding site [ion binding]; other site
1298917004350	putative DNA binding site [nucleotide binding]; other site
1298917004351	Bacterial transcriptional regulator; Region: IclR; pfam01614
1298917004352	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917004353	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1298917004354	putative substrate translocation pore; other site
1298917004355	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917004356	heat shock protein HtpX; Provisional; Region: PRK05457
1298917004357	carboxy-terminal protease; Provisional; Region: PRK11186
1298917004358	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1298917004359	protein binding site [polypeptide binding]; other site
1298917004360	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1298917004361	Catalytic dyad [active]
1298917004362	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1298917004363	ProP expression regulator; Provisional; Region: PRK04950
1298917004364	ProQ/FINO family; Region: ProQ; pfam04352
1298917004365	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1298917004366	GAF domain; Region: GAF_2; pfam13185
1298917004367	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1298917004368	Paraquat-inducible protein A; Region: PqiA; pfam04403
1298917004369	Paraquat-inducible protein A; Region: PqiA; pfam04403
1298917004370	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1298917004371	mce related protein; Region: MCE; pfam02470
1298917004372	mce related protein; Region: MCE; pfam02470
1298917004373	mce related protein; Region: MCE; pfam02470
1298917004374	mce related protein; Region: MCE; pfam02470
1298917004375	mce related protein; Region: MCE; pfam02470
1298917004376	mce related protein; Region: MCE; pfam02470
1298917004377	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1298917004378	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1298917004379	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
1298917004380	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1298917004381	type III secretion protein SopE2; Provisional; Region: PRK15280
1298917004382	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
1298917004383	SopE GEF domain; Region: SopE_GEF; pfam07487
1298917004384	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
1298917004385	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917004386	Coenzyme A binding pocket [chemical binding]; other site
1298917004387	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1298917004388	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1298917004389	EamA-like transporter family; Region: EamA; pfam00892
1298917004390	EamA-like transporter family; Region: EamA; pfam00892
1298917004391	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
1298917004392	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1298917004393	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1298917004394	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
1298917004395	ADP-ribose binding site [chemical binding]; other site
1298917004396	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1298917004397	Phage terminase large subunit (GpA); Region: Terminase_GpA; pfam05876
1298917004398	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1298917004399	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1298917004400	exonuclease VIII; Reviewed; Region: PRK09709
1298917004401	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1298917004402	DNA binding site [nucleotide binding]
1298917004403	active site
1298917004404	Int/Topo IB signature motif; other site
1298917004405	type III secretion protein SopE; Provisional; Region: PRK15279
1298917004406	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
1298917004407	SopE GEF domain; Region: SopE_GEF; pfam07487
1298917004408	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1298917004409	Phage Tail Collar Domain; Region: Collar; pfam07484
1298917004410	Phage-related protein, tail component [Function unknown]; Region: COG4723
1298917004411	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1298917004412	MPN+ (JAMM) motif; other site
1298917004413	Zinc-binding site [ion binding]; other site
1298917004414	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1298917004415	NlpC/P60 family; Region: NLPC_P60; cl17555
1298917004416	Phage-related protein [Function unknown]; Region: gp18; COG4672
1298917004417	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1298917004418	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1298917004419	E-class dimer interface [polypeptide binding]; other site
1298917004420	P-class dimer interface [polypeptide binding]; other site
1298917004421	active site
1298917004422	Cu2+ binding site [ion binding]; other site
1298917004423	Zn2+ binding site [ion binding]; other site
1298917004424	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1298917004425	Phage-related protein [Function unknown]; Region: COG4718
1298917004426	Phage-related minor tail protein [Function unknown]; Region: COG5281
1298917004427	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1298917004428	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1298917004429	Minor tail protein T; Region: Phage_tail_T; cl05636
1298917004430	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
1298917004431	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1298917004432	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1298917004433	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1298917004434	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
1298917004435	Uncharacterized conserved protein [Function unknown]; Region: COG5471
1298917004436	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1298917004437	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1298917004438	oligomer interface [polypeptide binding]; other site
1298917004439	active site residues [active]
1298917004440	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
1298917004441	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1298917004442	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1298917004443	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1298917004444	Domain of unknown function (DUF1859); Region: DUF1859; pfam08948
1298917004445	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1298917004446	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1298917004447	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1298917004448	catalytic residues [active]
1298917004449	phage holin, lambda family; Region: holin_lambda; TIGR01594
1298917004450	PipA protein; Region: PipA; pfam07108
1298917004451	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
1298917004452	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1298917004453	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1298917004454	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
1298917004455	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1298917004456	SCP-2 sterol transfer family; Region: SCP2; cl01225
1298917004457	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1298917004458	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1298917004459	metal binding site [ion binding]; metal-binding site
1298917004460	active site
1298917004461	I-site; other site
1298917004462	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1298917004463	Replication protein P; Region: Phage_lambda_P; pfam06992
1298917004464	Protein of unknown function (DUF1376); Region: DUF1376; cl01531
1298917004465	primosomal protein DnaI; Provisional; Region: PRK02854
1298917004466	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917004467	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1298917004468	non-specific DNA binding site [nucleotide binding]; other site
1298917004469	salt bridge; other site
1298917004470	sequence-specific DNA binding site [nucleotide binding]; other site
1298917004471	transcriptional repressor DicA; Reviewed; Region: PRK09706
1298917004472	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917004473	sequence-specific DNA binding site [nucleotide binding]; other site
1298917004474	salt bridge; other site
1298917004475	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
1298917004476	exonuclease VIII; Reviewed; Region: PRK09709
1298917004477	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1298917004478	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
1298917004479	recombination and repair protein RecT; Reviewed; Region: recT; PRK09846
1298917004480	hypothetical protein; Provisional; Region: PRK09750
1298917004481	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1298917004482	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1298917004483	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1298917004484	dimer interface [polypeptide binding]; other site
1298917004485	active site
1298917004486	Int/Topo IB signature motif; other site
1298917004487	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1298917004488	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1298917004489	hypothetical protein; Provisional; Region: PRK10301
1298917004490	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1298917004491	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1298917004492	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
1298917004493	exodeoxyribonuclease X; Provisional; Region: PRK07983
1298917004494	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1298917004495	active site
1298917004496	catalytic site [active]
1298917004497	substrate binding site [chemical binding]; other site
1298917004498	protease 2; Provisional; Region: PRK10115
1298917004499	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1298917004500	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1298917004501	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1298917004502	putative metal binding site [ion binding]; other site
1298917004503	hypothetical protein; Provisional; Region: PRK13680
1298917004504	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
1298917004505	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1298917004506	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1298917004507	ATP-grasp domain; Region: ATP-grasp; pfam02222
1298917004508	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1298917004509	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1298917004510	active site
1298917004511	intersubunit interface [polypeptide binding]; other site
1298917004512	catalytic residue [active]
1298917004513	phosphogluconate dehydratase; Validated; Region: PRK09054
1298917004514	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1298917004515	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1298917004516	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1298917004517	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1298917004518	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1298917004519	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1298917004520	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1298917004521	putative active site [active]
1298917004522	pyruvate kinase; Provisional; Region: PRK05826
1298917004523	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1298917004524	domain interfaces; other site
1298917004525	active site
1298917004526	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1298917004527	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1298917004528	putative acyl-acceptor binding pocket; other site
1298917004529	putative peptidase; Provisional; Region: PRK11649
1298917004530	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1298917004531	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1298917004532	Peptidase family M23; Region: Peptidase_M23; pfam01551
1298917004533	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1298917004534	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1298917004535	metal binding site [ion binding]; metal-binding site
1298917004536	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1298917004537	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1298917004538	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1298917004539	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1298917004540	ABC-ATPase subunit  interface; other site
1298917004541	dimer interface [polypeptide binding]; other site
1298917004542	putative PBP binding regions; other site
1298917004543	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1298917004544	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917004545	Walker A motif; other site
1298917004546	ATP binding site [chemical binding]; other site
1298917004547	Walker B motif; other site
1298917004548	arginine finger; other site
1298917004549	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1298917004550	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1298917004551	RuvA N terminal domain; Region: RuvA_N; pfam01330
1298917004552	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1298917004553	hypothetical protein; Provisional; Region: PRK11470
1298917004554	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1298917004555	active site
1298917004556	putative DNA-binding cleft [nucleotide binding]; other site
1298917004557	dimer interface [polypeptide binding]; other site
1298917004558	hypothetical protein; Validated; Region: PRK00110
1298917004559	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1298917004560	nudix motif; other site
1298917004561	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1298917004562	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1298917004563	dimer interface [polypeptide binding]; other site
1298917004564	anticodon binding site; other site
1298917004565	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1298917004566	homodimer interface [polypeptide binding]; other site
1298917004567	motif 1; other site
1298917004568	active site
1298917004569	motif 2; other site
1298917004570	GAD domain; Region: GAD; pfam02938
1298917004571	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1298917004572	active site
1298917004573	motif 3; other site
1298917004574	hypothetical protein; Provisional; Region: PRK10302
1298917004575	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1298917004576	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917004577	S-adenosylmethionine binding site [chemical binding]; other site
1298917004578	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917004579	S-adenosylmethionine binding site [chemical binding]; other site
1298917004580	copper homeostasis protein CutC; Provisional; Region: PRK11572
1298917004581	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1298917004582	putative metal binding site [ion binding]; other site
1298917004583	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1298917004584	arginyl-tRNA synthetase; Region: argS; TIGR00456
1298917004585	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1298917004586	active site
1298917004587	HIGH motif; other site
1298917004588	KMSK motif region; other site
1298917004589	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1298917004590	tRNA binding surface [nucleotide binding]; other site
1298917004591	anticodon binding site; other site
1298917004592	penicillin-binding protein 2; Provisional; Region: PRK10795
1298917004593	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1298917004594	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1298917004595	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1298917004596	Flagellar protein FlhE; Region: FlhE; pfam06366
1298917004597	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1298917004598	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1298917004599	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917004600	active site
1298917004601	phosphorylation site [posttranslational modification]
1298917004602	intermolecular recognition site; other site
1298917004603	dimerization interface [polypeptide binding]; other site
1298917004604	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1298917004605	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917004606	active site
1298917004607	phosphorylation site [posttranslational modification]
1298917004608	intermolecular recognition site; other site
1298917004609	dimerization interface [polypeptide binding]; other site
1298917004610	CheB methylesterase; Region: CheB_methylest; pfam01339
1298917004611	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1298917004612	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1298917004613	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917004614	S-adenosylmethionine binding site [chemical binding]; other site
1298917004615	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1298917004616	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1298917004617	dimer interface [polypeptide binding]; other site
1298917004618	ligand binding site [chemical binding]; other site
1298917004619	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917004620	dimerization interface [polypeptide binding]; other site
1298917004621	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1298917004622	dimer interface [polypeptide binding]; other site
1298917004623	putative CheW interface [polypeptide binding]; other site
1298917004624	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1298917004625	putative CheA interaction surface; other site
1298917004626	chemotaxis protein CheA; Provisional; Region: PRK10547
1298917004627	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1298917004628	putative binding surface; other site
1298917004629	active site
1298917004630	CheY binding; Region: CheY-binding; pfam09078
1298917004631	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1298917004632	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917004633	ATP binding site [chemical binding]; other site
1298917004634	Mg2+ binding site [ion binding]; other site
1298917004635	G-X-G motif; other site
1298917004636	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1298917004637	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1298917004638	flagellar motor protein MotA; Validated; Region: PRK09110
1298917004639	transcriptional activator FlhC; Provisional; Region: PRK12722
1298917004640	transcriptional activator FlhD; Provisional; Region: PRK02909
1298917004641	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1298917004642	Ligand Binding Site [chemical binding]; other site
1298917004643	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1298917004644	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1298917004645	active site
1298917004646	homotetramer interface [polypeptide binding]; other site
1298917004647	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
1298917004648	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1298917004649	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1298917004650	DJ-1 family protein; Region: not_thiJ; TIGR01383
1298917004651	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1298917004652	conserved cys residue [active]
1298917004653	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1298917004654	Ferritin-like domain; Region: Ferritin; pfam00210
1298917004655	ferroxidase diiron center [ion binding]; other site
1298917004656	hypothetical protein; Provisional; Region: PRK09273
1298917004657	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
1298917004658	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
1298917004659	YecR-like lipoprotein; Region: YecR; pfam13992
1298917004660	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1298917004661	Ferritin-like domain; Region: Ferritin; pfam00210
1298917004662	ferroxidase diiron center [ion binding]; other site
1298917004663	probable metal-binding protein; Region: matur_matur; TIGR03853
1298917004664	tyrosine transporter TyrP; Provisional; Region: PRK15132
1298917004665	aromatic amino acid transport protein; Region: araaP; TIGR00837
1298917004666	hypothetical protein; Provisional; Region: PRK10396
1298917004667	yecA family protein; Region: ygfB_yecA; TIGR02292
1298917004668	SEC-C motif; Region: SEC-C; pfam02810
1298917004669	glucose-6-phosphate 1-dehydrogenase; Region: PLN02640
1298917004670	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
1298917004671	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
1298917004672	NlpC/P60 family; Region: NLPC_P60; cl17555
1298917004673	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1298917004674	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1298917004675	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1298917004676	GIY-YIG motif/motif A; other site
1298917004677	active site
1298917004678	catalytic site [active]
1298917004679	putative DNA binding site [nucleotide binding]; other site
1298917004680	metal binding site [ion binding]; metal-binding site
1298917004681	UvrB/uvrC motif; Region: UVR; pfam02151
1298917004682	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1298917004683	Helix-hairpin-helix motif; Region: HHH; pfam00633
1298917004684	response regulator; Provisional; Region: PRK09483
1298917004685	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917004686	active site
1298917004687	phosphorylation site [posttranslational modification]
1298917004688	intermolecular recognition site; other site
1298917004689	dimerization interface [polypeptide binding]; other site
1298917004690	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917004691	DNA binding residues [nucleotide binding]
1298917004692	dimerization interface [polypeptide binding]; other site
1298917004693	hypothetical protein; Provisional; Region: PRK10613
1298917004694	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1298917004695	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1298917004696	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917004697	DNA binding residues [nucleotide binding]
1298917004698	dimerization interface [polypeptide binding]; other site
1298917004699	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1298917004700	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1298917004701	Walker A/P-loop; other site
1298917004702	ATP binding site [chemical binding]; other site
1298917004703	Q-loop/lid; other site
1298917004704	ABC transporter signature motif; other site
1298917004705	Walker B; other site
1298917004706	D-loop; other site
1298917004707	H-loop/switch region; other site
1298917004708	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1298917004709	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1298917004710	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917004711	dimer interface [polypeptide binding]; other site
1298917004712	conserved gate region; other site
1298917004713	putative PBP binding loops; other site
1298917004714	ABC-ATPase subunit interface; other site
1298917004715	D-cysteine desulfhydrase; Validated; Region: PRK03910
1298917004716	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1298917004717	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917004718	catalytic residue [active]
1298917004719	cystine transporter subunit; Provisional; Region: PRK11260
1298917004720	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917004721	substrate binding pocket [chemical binding]; other site
1298917004722	membrane-bound complex binding site; other site
1298917004723	hinge residues; other site
1298917004724	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1298917004725	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1298917004726	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1298917004727	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1298917004728	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1298917004729	DNA binding residues [nucleotide binding]
1298917004730	flagellin; Validated; Region: PRK08026
1298917004731	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1298917004732	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1298917004733	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1298917004734	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1298917004735	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1298917004736	flagellar protein FliS; Validated; Region: fliS; PRK05685
1298917004737	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
1298917004738	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1298917004739	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1298917004740	active site
1298917004741	Na/Ca binding site [ion binding]; other site
1298917004742	catalytic site [active]
1298917004743	lipoprotein; Provisional; Region: PRK10397
1298917004744	putative inner membrane protein; Provisional; Region: PRK11099
1298917004745	Sulphur transport; Region: Sulf_transp; pfam04143
1298917004746	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1298917004747	CPxP  motif; other site
1298917004748	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1298917004749	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1298917004750	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1298917004751	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1298917004752	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1298917004753	FliG C-terminal domain; Region: FliG_C; pfam01706
1298917004754	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1298917004755	Flagellar assembly protein FliH; Region: FliH; pfam02108
1298917004756	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1298917004757	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1298917004758	Walker A motif/ATP binding site; other site
1298917004759	Walker B motif; other site
1298917004760	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1298917004761	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1298917004762	flagellar hook-length control protein; Provisional; Region: PRK10118
1298917004763	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
1298917004764	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1298917004765	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1298917004766	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1298917004767	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1298917004768	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1298917004769	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1298917004770	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1298917004771	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917004772	DNA binding residues [nucleotide binding]
1298917004773	dimerization interface [polypeptide binding]; other site
1298917004774	hypothetical protein; Provisional; Region: PRK10708
1298917004775	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1298917004776	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1298917004777	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917004778	active site
1298917004779	motif I; other site
1298917004780	motif II; other site
1298917004781	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1298917004782	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1298917004783	metal binding site [ion binding]; metal-binding site
1298917004784	active site
1298917004785	I-site; other site
1298917004786	Uncharacterized small protein [Function unknown]; Region: COG5475
1298917004787	hypothetical protein; Provisional; Region: PRK10062
1298917004788	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1298917004789	EamA-like transporter family; Region: EamA; pfam00892
1298917004790	EamA-like transporter family; Region: EamA; pfam00892
1298917004791	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1298917004792	additional DNA contacts [nucleotide binding]; other site
1298917004793	mismatch recognition site; other site
1298917004794	active site
1298917004795	zinc binding site [ion binding]; other site
1298917004796	DNA intercalation site [nucleotide binding]; other site
1298917004797	DNA cytosine methylase; Provisional; Region: PRK10458
1298917004798	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1298917004799	cofactor binding site; other site
1298917004800	DNA binding site [nucleotide binding]
1298917004801	substrate interaction site [chemical binding]; other site
1298917004802	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1298917004803	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1298917004804	Zn2+ binding site [ion binding]; other site
1298917004805	Mg2+ binding site [ion binding]; other site
1298917004806	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1298917004807	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1298917004808	trimer interface [polypeptide binding]; other site
1298917004809	eyelet of channel; other site
1298917004810	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1298917004811	DNA-binding site [nucleotide binding]; DNA binding site
1298917004812	RNA-binding motif; other site
1298917004813	dsRNA-gated channel SID-1; Region: SID-1_RNA_chan; pfam13965
1298917004814	Transposase; Region: HTH_Tnp_1; cl17663
1298917004815	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1298917004816	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1298917004817	Sel1-like repeats; Region: SEL1; smart00671
1298917004818	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1298917004819	Sel1-like repeats; Region: SEL1; smart00671
1298917004820	Sel1-like repeats; Region: SEL1; smart00671
1298917004821	RHS Repeat; Region: RHS_repeat; cl11982
1298917004822	RHS Repeat; Region: RHS_repeat; pfam05593
1298917004823	RHS Repeat; Region: RHS_repeat; pfam05593
1298917004824	RHS Repeat; Region: RHS_repeat; cl11982
1298917004825	RHS Repeat; Region: RHS_repeat; cl11982
1298917004826	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1298917004827	RHS Repeat; Region: RHS_repeat; pfam05593
1298917004828	RHS Repeat; Region: RHS_repeat; pfam05593
1298917004829	RHS protein; Region: RHS; pfam03527
1298917004830	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1298917004831	PAAR motif; Region: PAAR_motif; cl15808
1298917004832	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1298917004833	RHS Repeat; Region: RHS_repeat; pfam05593
1298917004834	RHS Repeat; Region: RHS_repeat; cl11982
1298917004835	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1298917004836	RHS Repeat; Region: RHS_repeat; pfam05593
1298917004837	RHS Repeat; Region: RHS_repeat; pfam05593
1298917004838	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1298917004839	RHS protein; Region: RHS; pfam03527
1298917004840	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1298917004841	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1298917004842	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1298917004843	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1298917004844	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1298917004845	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1298917004846	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1298917004847	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1298917004848	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1298917004849	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1298917004850	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
1298917004851	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1298917004852	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1298917004853	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
1298917004854	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
1298917004855	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
1298917004856	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
1298917004857	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1298917004858	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1298917004859	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917004860	Walker A motif; other site
1298917004861	ATP binding site [chemical binding]; other site
1298917004862	Walker B motif; other site
1298917004863	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917004864	Walker A motif; other site
1298917004865	ATP binding site [chemical binding]; other site
1298917004866	Walker B motif; other site
1298917004867	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083
1298917004868	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1298917004869	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1298917004870	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1298917004871	ImpA domain protein; Region: DUF3702; pfam12486
1298917004872	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1298917004873	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1298917004874	Protein of unknown function (DUF1311); Region: DUF1311; cl01530
1298917004875	YCII-related domain; Region: YCII; cl00999
1298917004876	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1298917004877	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1298917004878	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1298917004879	putative sialic acid transporter; Provisional; Region: PRK12307
1298917004880	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917004881	putative substrate translocation pore; other site
1298917004882	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1298917004883	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
1298917004884	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
1298917004885	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1298917004886	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1298917004887	putative active site cavity [active]
1298917004888	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
1298917004889	Na binding site [ion binding]; other site
1298917004890	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1298917004891	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1298917004892	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1298917004893	putative active site [active]
1298917004894	hypothetical protein; Provisional; Region: PRK10536
1298917004895	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1298917004896	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
1298917004897	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1298917004898	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1298917004899	Na binding site [ion binding]; other site
1298917004900	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1298917004901	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1298917004902	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917004903	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1298917004904	General stress protein [General function prediction only]; Region: GsiB; COG3729
1298917004905	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1298917004906	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1298917004907	hypothetical protein; Provisional; Region: PRK10174
1298917004908	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1298917004909	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1298917004910	catalytic core [active]
1298917004911	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1298917004912	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1298917004913	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1298917004914	catalytic residues [active]
1298917004915	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
1298917004916	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1298917004917	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1298917004918	catalytic residues [active]
1298917004919	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
1298917004920	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1298917004921	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1298917004922	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1298917004923	DsbD alpha interface [polypeptide binding]; other site
1298917004924	catalytic residues [active]
1298917004925	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
1298917004926	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1298917004927	HSP70 interaction site [polypeptide binding]; other site
1298917004928	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1298917004929	substrate binding site [polypeptide binding]; other site
1298917004930	dimer interface [polypeptide binding]; other site
1298917004931	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
1298917004932	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
1298917004933	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
1298917004934	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917004935	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1298917004936	putative substrate translocation pore; other site
1298917004937	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
1298917004938	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
1298917004939	putative substrate binding pocket [chemical binding]; other site
1298917004940	trimer interface [polypeptide binding]; other site
1298917004941	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
1298917004942	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1298917004943	putative active site [active]
1298917004944	putative metal binding site [ion binding]; other site
1298917004945	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
1298917004946	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
1298917004947	NAD binding site [chemical binding]; other site
1298917004948	catalytic residues [active]
1298917004949	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
1298917004950	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1298917004951	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1298917004952	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1298917004953	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1298917004954	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
1298917004955	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1298917004956	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
1298917004957	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1298917004958	active site
1298917004959	homotetramer interface [polypeptide binding]; other site
1298917004960	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
1298917004961	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917004962	active site
1298917004963	phosphorylation site [posttranslational modification]
1298917004964	intermolecular recognition site; other site
1298917004965	dimerization interface [polypeptide binding]; other site
1298917004966	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917004967	DNA binding site [nucleotide binding]
1298917004968	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1298917004969	HAMP domain; Region: HAMP; pfam00672
1298917004970	dimerization interface [polypeptide binding]; other site
1298917004971	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917004972	dimer interface [polypeptide binding]; other site
1298917004973	phosphorylation site [posttranslational modification]
1298917004974	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917004975	ATP binding site [chemical binding]; other site
1298917004976	Mg2+ binding site [ion binding]; other site
1298917004977	G-X-G motif; other site
1298917004978	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
1298917004979	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
1298917004980	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
1298917004981	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
1298917004982	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
1298917004983	secreted effector protein PipB; Provisional; Region: PRK15197
1298917004984	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1298917004985	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1298917004986	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1298917004987	PipA protein; Region: PipA; pfam07108
1298917004988	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1298917004989	YccA-like proteins; Region: YccA_like; cd10433
1298917004990	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1298917004991	sulfur transfer protein TusE; Provisional; Region: PRK11508
1298917004992	acylphosphatase; Provisional; Region: PRK14426
1298917004993	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1298917004994	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917004995	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1298917004996	substrate binding site [chemical binding]; other site
1298917004997	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1298917004998	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1298917004999	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1298917005000	putative RNA binding site [nucleotide binding]; other site
1298917005001	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917005002	S-adenosylmethionine binding site [chemical binding]; other site
1298917005003	heat shock protein HspQ; Provisional; Region: PRK14129
1298917005004	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1298917005005	hypothetical protein; Provisional; Region: PRK03641
1298917005006	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
1298917005007	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1298917005008	active site
1298917005009	dimer interfaces [polypeptide binding]; other site
1298917005010	catalytic residues [active]
1298917005011	DNA helicase IV; Provisional; Region: helD; PRK11054
1298917005012	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1298917005013	Part of AAA domain; Region: AAA_19; pfam13245
1298917005014	Family description; Region: UvrD_C_2; pfam13538
1298917005015	Predicted membrane protein [Function unknown]; Region: COG3304
1298917005016	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1298917005017	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1298917005018	TIGR01666 family membrane protein; Region: YCCS
1298917005019	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1298917005020	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1298917005021	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
1298917005022	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1298917005023	cell division inhibitor SulA; Region: sula; TIGR00623
1298917005024	outer membrane protein A; Reviewed; Region: PRK10808
1298917005025	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1298917005026	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1298917005027	ligand binding site [chemical binding]; other site
1298917005028	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1298917005029	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1298917005030	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1298917005031	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1298917005032	active site 1 [active]
1298917005033	dimer interface [polypeptide binding]; other site
1298917005034	active site 2 [active]
1298917005035	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1298917005036	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1298917005037	paraquat-inducible protein B; Provisional; Region: PRK10807
1298917005038	mce related protein; Region: MCE; pfam02470
1298917005039	mce related protein; Region: MCE; pfam02470
1298917005040	mce related protein; Region: MCE; pfam02470
1298917005041	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1298917005042	Paraquat-inducible protein A; Region: PqiA; pfam04403
1298917005043	Paraquat-inducible protein A; Region: PqiA; pfam04403
1298917005044	ABC transporter ATPase component; Reviewed; Region: PRK11147
1298917005045	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917005046	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917005047	Walker A/P-loop; other site
1298917005048	Walker A/P-loop; other site
1298917005049	ATP binding site [chemical binding]; other site
1298917005050	ATP binding site [chemical binding]; other site
1298917005051	Q-loop/lid; other site
1298917005052	Q-loop/lid; other site
1298917005053	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1298917005054	ABC transporter signature motif; other site
1298917005055	Walker B; other site
1298917005056	D-loop; other site
1298917005057	ABC transporter; Region: ABC_tran_2; pfam12848
1298917005058	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1298917005059	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1298917005060	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1298917005061	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1298917005062	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917005063	S-adenosylmethionine binding site [chemical binding]; other site
1298917005064	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1298917005065	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1298917005066	MOSC domain; Region: MOSC; pfam03473
1298917005067	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1298917005068	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1298917005069	catalytic loop [active]
1298917005070	iron binding site [ion binding]; other site
1298917005071	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1298917005072	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1298917005073	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1298917005074	quinone interaction residues [chemical binding]; other site
1298917005075	active site
1298917005076	catalytic residues [active]
1298917005077	FMN binding site [chemical binding]; other site
1298917005078	substrate binding site [chemical binding]; other site
1298917005079	aminopeptidase N; Provisional; Region: pepN; PRK14015
1298917005080	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1298917005081	active site
1298917005082	Zn binding site [ion binding]; other site
1298917005083	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1298917005084	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1298917005085	active site
1298917005086	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1298917005087	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1298917005088	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1298917005089	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
1298917005090	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1298917005091	catalytic residue [active]
1298917005092	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1298917005093	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1298917005094	putative DNA binding site [nucleotide binding]; other site
1298917005095	putative Zn2+ binding site [ion binding]; other site
1298917005096	AsnC family; Region: AsnC_trans_reg; pfam01037
1298917005097	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1298917005098	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1298917005099	putative dimer interface [polypeptide binding]; other site
1298917005100	putative anticodon binding site; other site
1298917005101	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1298917005102	homodimer interface [polypeptide binding]; other site
1298917005103	motif 1; other site
1298917005104	motif 2; other site
1298917005105	active site
1298917005106	motif 3; other site
1298917005107	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1298917005108	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1298917005109	trimer interface [polypeptide binding]; other site
1298917005110	eyelet of channel; other site
1298917005111	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1298917005112	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917005113	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917005114	homodimer interface [polypeptide binding]; other site
1298917005115	catalytic residue [active]
1298917005116	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1298917005117	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1298917005118	Peptidase M15; Region: Peptidase_M15_3; cl01194
1298917005119	murein L,D-transpeptidase; Provisional; Region: PRK10594
1298917005120	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1298917005121	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1298917005122	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1298917005123	condesin subunit E; Provisional; Region: PRK05256
1298917005124	condesin subunit F; Provisional; Region: PRK05260
1298917005125	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1298917005126	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917005127	S-adenosylmethionine binding site [chemical binding]; other site
1298917005128	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1298917005129	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1298917005130	putative active site [active]
1298917005131	hypothetical protein; Provisional; Region: PRK10593
1298917005132	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1298917005133	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1298917005134	Ligand binding site; other site
1298917005135	oligomer interface; other site
1298917005136	hypothetical protein; Provisional; Region: PRK11827
1298917005137	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1298917005138	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1298917005139	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1298917005140	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1298917005141	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1298917005142	Walker A/P-loop; other site
1298917005143	ATP binding site [chemical binding]; other site
1298917005144	Q-loop/lid; other site
1298917005145	ABC transporter signature motif; other site
1298917005146	Walker B; other site
1298917005147	D-loop; other site
1298917005148	H-loop/switch region; other site
1298917005149	ComEC family competence protein; Provisional; Region: PRK11539
1298917005150	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1298917005151	Competence protein; Region: Competence; pfam03772
1298917005152	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1298917005153	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1298917005154	IHF dimer interface [polypeptide binding]; other site
1298917005155	IHF - DNA interface [nucleotide binding]; other site
1298917005156	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1298917005157	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1298917005158	RNA binding site [nucleotide binding]; other site
1298917005159	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1298917005160	RNA binding site [nucleotide binding]; other site
1298917005161	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1298917005162	RNA binding site [nucleotide binding]; other site
1298917005163	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1298917005164	RNA binding site [nucleotide binding]; other site
1298917005165	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1298917005166	RNA binding site [nucleotide binding]; other site
1298917005167	cytidylate kinase; Provisional; Region: cmk; PRK00023
1298917005168	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1298917005169	CMP-binding site; other site
1298917005170	The sites determining sugar specificity; other site
1298917005171	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1298917005172	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1298917005173	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
1298917005174	putative active site [active]
1298917005175	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1298917005176	homodimer interface [polypeptide binding]; other site
1298917005177	substrate-cofactor binding pocket; other site
1298917005178	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917005179	catalytic residue [active]
1298917005180	Predicted membrane protein [Function unknown]; Region: COG2323
1298917005181	uncharacterized domain; Region: TIGR00702
1298917005182	YcaO-like family; Region: YcaO; pfam02624
1298917005183	formate transporter; Provisional; Region: PRK10805
1298917005184	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1298917005185	Pyruvate formate lyase 1; Region: PFL1; cd01678
1298917005186	coenzyme A binding site [chemical binding]; other site
1298917005187	active site
1298917005188	catalytic residues [active]
1298917005189	glycine loop; other site
1298917005190	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
1298917005191	integrase; Provisional; Region: int; PHA02601
1298917005192	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1298917005193	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917005194	FeS/SAM binding site; other site
1298917005195	inner membrane transporter YjeM; Provisional; Region: PRK15238
1298917005196	putative MFS family transporter protein; Provisional; Region: PRK03633
1298917005197	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917005198	putative substrate translocation pore; other site
1298917005199	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1298917005200	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1298917005201	4Fe-4S binding domain; Region: Fer4; pfam00037
1298917005202	seryl-tRNA synthetase; Provisional; Region: PRK05431
1298917005203	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1298917005204	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1298917005205	dimer interface [polypeptide binding]; other site
1298917005206	active site
1298917005207	motif 1; other site
1298917005208	motif 2; other site
1298917005209	motif 3; other site
1298917005210	recombination factor protein RarA; Reviewed; Region: PRK13342
1298917005211	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917005212	Walker A motif; other site
1298917005213	ATP binding site [chemical binding]; other site
1298917005214	Walker B motif; other site
1298917005215	arginine finger; other site
1298917005216	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1298917005217	periplasmic chaperone LolA; Region: lolA; TIGR00547
1298917005218	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1298917005219	DNA translocase FtsK; Provisional; Region: PRK10263
1298917005220	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1298917005221	DNA translocase FtsK; Provisional; Region: PRK10263
1298917005222	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1298917005223	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1298917005224	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1298917005225	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1298917005226	putative DNA binding site [nucleotide binding]; other site
1298917005227	putative Zn2+ binding site [ion binding]; other site
1298917005228	AsnC family; Region: AsnC_trans_reg; pfam01037
1298917005229	thioredoxin reductase; Provisional; Region: PRK10262
1298917005230	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1298917005231	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917005232	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1298917005233	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1298917005234	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917005235	Walker A/P-loop; other site
1298917005236	ATP binding site [chemical binding]; other site
1298917005237	Q-loop/lid; other site
1298917005238	ABC transporter signature motif; other site
1298917005239	Walker B; other site
1298917005240	D-loop; other site
1298917005241	H-loop/switch region; other site
1298917005242	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1298917005243	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1298917005244	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917005245	Walker A/P-loop; other site
1298917005246	ATP binding site [chemical binding]; other site
1298917005247	Q-loop/lid; other site
1298917005248	ABC transporter signature motif; other site
1298917005249	Walker B; other site
1298917005250	D-loop; other site
1298917005251	H-loop/switch region; other site
1298917005252	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1298917005253	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1298917005254	rRNA binding site [nucleotide binding]; other site
1298917005255	predicted 30S ribosome binding site; other site
1298917005256	LysR family transcriptional regulator; Provisional; Region: PRK14997
1298917005257	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917005258	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
1298917005259	putative effector binding pocket; other site
1298917005260	putative dimerization interface [polypeptide binding]; other site
1298917005261	Pirin-related protein [General function prediction only]; Region: COG1741
1298917005262	Pirin; Region: Pirin; pfam02678
1298917005263	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1298917005264	Isochorismatase family; Region: Isochorismatase; pfam00857
1298917005265	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1298917005266	catalytic triad [active]
1298917005267	dimer interface [polypeptide binding]; other site
1298917005268	conserved cis-peptide bond; other site
1298917005269	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1298917005270	DNA binding site [nucleotide binding]
1298917005271	active site
1298917005272	Int/Topo IB signature motif; other site
1298917005273	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1298917005274	Clp amino terminal domain; Region: Clp_N; pfam02861
1298917005275	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917005276	Walker A motif; other site
1298917005277	ATP binding site [chemical binding]; other site
1298917005278	Walker B motif; other site
1298917005279	arginine finger; other site
1298917005280	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917005281	Walker A motif; other site
1298917005282	ATP binding site [chemical binding]; other site
1298917005283	Walker B motif; other site
1298917005284	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1298917005285	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1298917005286	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1298917005287	DNA-binding site [nucleotide binding]; DNA binding site
1298917005288	RNA-binding motif; other site
1298917005289	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1298917005290	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1298917005291	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917005292	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1298917005293	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1298917005294	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1298917005295	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1298917005296	putative active site [active]
1298917005297	putative metal-binding site [ion binding]; other site
1298917005298	Predicted membrane protein [Function unknown]; Region: COG2431
1298917005299	hybrid cluster protein; Provisional; Region: PRK05290
1298917005300	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1298917005301	ACS interaction site; other site
1298917005302	CODH interaction site; other site
1298917005303	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1298917005304	hybrid metal cluster; other site
1298917005305	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1298917005306	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1298917005307	FAD binding pocket [chemical binding]; other site
1298917005308	FAD binding motif [chemical binding]; other site
1298917005309	phosphate binding motif [ion binding]; other site
1298917005310	beta-alpha-beta structure motif; other site
1298917005311	NAD binding pocket [chemical binding]; other site
1298917005312	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1298917005313	catalytic loop [active]
1298917005314	iron binding site [ion binding]; other site
1298917005315	pyruvate dehydrogenase; Provisional; Region: PRK09124
1298917005316	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1298917005317	PYR/PP interface [polypeptide binding]; other site
1298917005318	dimer interface [polypeptide binding]; other site
1298917005319	tetramer interface [polypeptide binding]; other site
1298917005320	TPP binding site [chemical binding]; other site
1298917005321	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1298917005322	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1298917005323	TPP-binding site [chemical binding]; other site
1298917005324	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1298917005325	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1298917005326	tetramer interface [polypeptide binding]; other site
1298917005327	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917005328	catalytic residue [active]
1298917005329	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1298917005330	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1298917005331	putative NAD(P) binding site [chemical binding]; other site
1298917005332	putative active site [active]
1298917005333	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1298917005334	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1298917005335	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1298917005336	NAD(P) binding site [chemical binding]; other site
1298917005337	active site
1298917005338	putative lipoprotein; Provisional; Region: PRK10533
1298917005339	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1298917005340	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917005341	Walker A/P-loop; other site
1298917005342	ATP binding site [chemical binding]; other site
1298917005343	Q-loop/lid; other site
1298917005344	ABC transporter signature motif; other site
1298917005345	Walker B; other site
1298917005346	D-loop; other site
1298917005347	H-loop/switch region; other site
1298917005348	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1298917005349	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917005350	substrate binding pocket [chemical binding]; other site
1298917005351	membrane-bound complex binding site; other site
1298917005352	hinge residues; other site
1298917005353	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1298917005354	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917005355	dimer interface [polypeptide binding]; other site
1298917005356	conserved gate region; other site
1298917005357	putative PBP binding loops; other site
1298917005358	ABC-ATPase subunit interface; other site
1298917005359	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917005360	dimer interface [polypeptide binding]; other site
1298917005361	conserved gate region; other site
1298917005362	putative PBP binding loops; other site
1298917005363	ABC-ATPase subunit interface; other site
1298917005364	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1298917005365	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917005366	substrate binding pocket [chemical binding]; other site
1298917005367	membrane-bound complex binding site; other site
1298917005368	hinge residues; other site
1298917005369	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1298917005370	Sulfatase; Region: Sulfatase; cl17466
1298917005371	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1298917005372	active site
1298917005373	P-loop; other site
1298917005374	phosphorylation site [posttranslational modification]
1298917005375	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1298917005376	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1298917005377	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917005378	S-adenosylmethionine binding site [chemical binding]; other site
1298917005379	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1298917005380	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1298917005381	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917005382	dimer interface [polypeptide binding]; other site
1298917005383	conserved gate region; other site
1298917005384	putative PBP binding loops; other site
1298917005385	ABC-ATPase subunit interface; other site
1298917005386	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917005387	dimer interface [polypeptide binding]; other site
1298917005388	conserved gate region; other site
1298917005389	putative PBP binding loops; other site
1298917005390	ABC-ATPase subunit interface; other site
1298917005391	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1298917005392	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917005393	Walker A/P-loop; other site
1298917005394	ATP binding site [chemical binding]; other site
1298917005395	Q-loop/lid; other site
1298917005396	ABC transporter signature motif; other site
1298917005397	Walker B; other site
1298917005398	D-loop; other site
1298917005399	H-loop/switch region; other site
1298917005400	TOBE domain; Region: TOBE_2; pfam08402
1298917005401	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1298917005402	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1298917005403	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1298917005404	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1298917005405	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1298917005406	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1298917005407	dimer interface [polypeptide binding]; other site
1298917005408	FMN binding site [chemical binding]; other site
1298917005409	NADPH bind site [chemical binding]; other site
1298917005410	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
1298917005411	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1298917005412	GSH binding site [chemical binding]; other site
1298917005413	catalytic residues [active]
1298917005414	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1298917005415	putative transporter; Provisional; Region: PRK04972
1298917005416	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1298917005417	TrkA-C domain; Region: TrkA_C; pfam02080
1298917005418	TrkA-C domain; Region: TrkA_C; pfam02080
1298917005419	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1298917005420	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
1298917005421	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917005422	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1298917005423	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917005424	putative substrate translocation pore; other site
1298917005425	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1298917005426	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1298917005427	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917005428	active site
1298917005429	motif I; other site
1298917005430	motif II; other site
1298917005431	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917005432	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1298917005433	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917005434	putative substrate translocation pore; other site
1298917005435	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1298917005436	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1298917005437	active site
1298917005438	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1298917005439	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1298917005440	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917005441	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1298917005442	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1298917005443	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1298917005444	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1298917005445	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1298917005446	putative C-terminal domain interface [polypeptide binding]; other site
1298917005447	putative GSH binding site (G-site) [chemical binding]; other site
1298917005448	putative dimer interface [polypeptide binding]; other site
1298917005449	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1298917005450	putative N-terminal domain interface [polypeptide binding]; other site
1298917005451	putative dimer interface [polypeptide binding]; other site
1298917005452	putative substrate binding pocket (H-site) [chemical binding]; other site
1298917005453	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1298917005454	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917005455	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917005456	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421
1298917005457	putative dimerization interface [polypeptide binding]; other site
1298917005458	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
1298917005459	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1298917005460	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
1298917005461	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1298917005462	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1298917005463	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1298917005464	active site
1298917005465	Uncharacterized conserved protein [Function unknown]; Region: COG3777
1298917005466	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1298917005467	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1298917005468	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1298917005469	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1298917005470	Ligand binding site [chemical binding]; other site
1298917005471	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1298917005472	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1298917005473	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1298917005474	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1298917005475	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1298917005476	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917005477	FeS/SAM binding site; other site
1298917005478	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1298917005479	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917005480	conserved gate region; other site
1298917005481	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1298917005482	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917005483	dimer interface [polypeptide binding]; other site
1298917005484	conserved gate region; other site
1298917005485	putative PBP binding loops; other site
1298917005486	ABC-ATPase subunit interface; other site
1298917005487	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1298917005488	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1298917005489	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1298917005490	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1298917005491	Walker A/P-loop; other site
1298917005492	ATP binding site [chemical binding]; other site
1298917005493	Q-loop/lid; other site
1298917005494	ABC transporter signature motif; other site
1298917005495	Walker B; other site
1298917005496	D-loop; other site
1298917005497	H-loop/switch region; other site
1298917005498	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1298917005499	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1298917005500	Walker A/P-loop; other site
1298917005501	ATP binding site [chemical binding]; other site
1298917005502	Q-loop/lid; other site
1298917005503	ABC transporter signature motif; other site
1298917005504	Walker B; other site
1298917005505	D-loop; other site
1298917005506	H-loop/switch region; other site
1298917005507	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1298917005508	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1298917005509	catalytic nucleophile [active]
1298917005510	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1298917005511	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1298917005512	dimer interface [polypeptide binding]; other site
1298917005513	putative functional site; other site
1298917005514	putative MPT binding site; other site
1298917005515	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1298917005516	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1298917005517	ATP binding site [chemical binding]; other site
1298917005518	substrate interface [chemical binding]; other site
1298917005519	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1298917005520	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917005521	FeS/SAM binding site; other site
1298917005522	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1298917005523	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1298917005524	dimer interface [polypeptide binding]; other site
1298917005525	active site
1298917005526	glycine loop; other site
1298917005527	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1298917005528	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917005529	active site
1298917005530	motif I; other site
1298917005531	motif II; other site
1298917005532	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917005533	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1298917005534	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1298917005535	transmembrane helices; other site
1298917005536	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1298917005537	manganese transport regulator MntR; Provisional; Region: PRK11050
1298917005538	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1298917005539	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1298917005540	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1298917005541	Sulfatase; Region: Sulfatase; pfam00884
1298917005542	outer membrane protein X; Provisional; Region: ompX; PRK09408
1298917005543	threonine and homoserine efflux system; Provisional; Region: PRK10532
1298917005544	EamA-like transporter family; Region: EamA; pfam00892
1298917005545	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1298917005546	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1298917005547	dimerization interface [polypeptide binding]; other site
1298917005548	DPS ferroxidase diiron center [ion binding]; other site
1298917005549	ion pore; other site
1298917005550	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1298917005551	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917005552	substrate binding pocket [chemical binding]; other site
1298917005553	membrane-bound complex binding site; other site
1298917005554	hinge residues; other site
1298917005555	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1298917005556	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917005557	dimer interface [polypeptide binding]; other site
1298917005558	conserved gate region; other site
1298917005559	putative PBP binding loops; other site
1298917005560	ABC-ATPase subunit interface; other site
1298917005561	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1298917005562	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1298917005563	Walker A/P-loop; other site
1298917005564	ATP binding site [chemical binding]; other site
1298917005565	Q-loop/lid; other site
1298917005566	ABC transporter signature motif; other site
1298917005567	Walker B; other site
1298917005568	D-loop; other site
1298917005569	H-loop/switch region; other site
1298917005570	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1298917005571	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1298917005572	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
1298917005573	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1298917005574	hypothetical protein; Provisional; Region: PRK11019
1298917005575	hypothetical protein; Provisional; Region: PRK10259
1298917005576	glycosyl transferase family protein; Provisional; Region: PRK08136
1298917005577	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1298917005578	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1298917005579	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1298917005580	ATP binding site [chemical binding]; other site
1298917005581	Mg++ binding site [ion binding]; other site
1298917005582	motif III; other site
1298917005583	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917005584	nucleotide binding region [chemical binding]; other site
1298917005585	ATP-binding site [chemical binding]; other site
1298917005586	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1298917005587	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917005588	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1298917005589	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1298917005590	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1298917005591	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917005592	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1298917005593	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1298917005594	Walker A/P-loop; other site
1298917005595	ATP binding site [chemical binding]; other site
1298917005596	Q-loop/lid; other site
1298917005597	ABC transporter signature motif; other site
1298917005598	Walker B; other site
1298917005599	D-loop; other site
1298917005600	H-loop/switch region; other site
1298917005601	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1298917005602	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1298917005603	Walker A/P-loop; other site
1298917005604	ATP binding site [chemical binding]; other site
1298917005605	Q-loop/lid; other site
1298917005606	ABC transporter signature motif; other site
1298917005607	Walker B; other site
1298917005608	D-loop; other site
1298917005609	H-loop/switch region; other site
1298917005610	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1298917005611	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1298917005612	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1298917005613	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1298917005614	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1298917005615	Predicted integral membrane protein [Function unknown]; Region: COG0392
1298917005616	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1298917005617	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1298917005618	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1298917005619	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1298917005620	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1298917005621	MoaE homodimer interface [polypeptide binding]; other site
1298917005622	MoaD interaction [polypeptide binding]; other site
1298917005623	active site residues [active]
1298917005624	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1298917005625	MoaE interaction surface [polypeptide binding]; other site
1298917005626	MoeB interaction surface [polypeptide binding]; other site
1298917005627	thiocarboxylated glycine; other site
1298917005628	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1298917005629	trimer interface [polypeptide binding]; other site
1298917005630	dimer interface [polypeptide binding]; other site
1298917005631	putative active site [active]
1298917005632	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1298917005633	MPT binding site; other site
1298917005634	trimer interface [polypeptide binding]; other site
1298917005635	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1298917005636	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917005637	FeS/SAM binding site; other site
1298917005638	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1298917005639	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1298917005640	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1298917005641	putative substrate binding pocket [chemical binding]; other site
1298917005642	dimer interface [polypeptide binding]; other site
1298917005643	phosphate binding site [ion binding]; other site
1298917005644	excinuclease ABC subunit B; Provisional; Region: PRK05298
1298917005645	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1298917005646	ATP binding site [chemical binding]; other site
1298917005647	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917005648	nucleotide binding region [chemical binding]; other site
1298917005649	ATP-binding site [chemical binding]; other site
1298917005650	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1298917005651	UvrB/uvrC motif; Region: UVR; pfam02151
1298917005652	AAA domain; Region: AAA_26; pfam13500
1298917005653	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1298917005654	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1298917005655	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1298917005656	substrate-cofactor binding pocket; other site
1298917005657	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917005658	catalytic residue [active]
1298917005659	biotin synthase; Provisional; Region: PRK15108
1298917005660	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917005661	FeS/SAM binding site; other site
1298917005662	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1298917005663	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1298917005664	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1298917005665	inhibitor-cofactor binding pocket; inhibition site
1298917005666	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917005667	catalytic residue [active]
1298917005668	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1298917005669	substrate binding site [chemical binding]; other site
1298917005670	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1298917005671	active sites [active]
1298917005672	tetramer interface [polypeptide binding]; other site
1298917005673	histidine utilization repressor; Provisional; Region: PRK14999
1298917005674	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917005675	DNA-binding site [nucleotide binding]; DNA binding site
1298917005676	UTRA domain; Region: UTRA; pfam07702
1298917005677	imidazolonepropionase; Validated; Region: PRK09356
1298917005678	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1298917005679	active site
1298917005680	acyl-CoA thioesterase; Provisional; Region: PRK10531
1298917005681	putative pectinesterase; Region: PLN02432; cl01911
1298917005682	6-phosphogluconolactonase; Provisional; Region: PRK11028
1298917005683	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1298917005684	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917005685	active site
1298917005686	motif I; other site
1298917005687	motif II; other site
1298917005688	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917005689	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1298917005690	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917005691	Walker A/P-loop; other site
1298917005692	ATP binding site [chemical binding]; other site
1298917005693	Q-loop/lid; other site
1298917005694	ABC transporter signature motif; other site
1298917005695	Walker B; other site
1298917005696	D-loop; other site
1298917005697	H-loop/switch region; other site
1298917005698	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1298917005699	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1298917005700	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917005701	dimer interface [polypeptide binding]; other site
1298917005702	conserved gate region; other site
1298917005703	putative PBP binding loops; other site
1298917005704	ABC-ATPase subunit interface; other site
1298917005705	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1298917005706	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917005707	substrate binding pocket [chemical binding]; other site
1298917005708	membrane-bound complex binding site; other site
1298917005709	hinge residues; other site
1298917005710	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1298917005711	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1298917005712	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1298917005713	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1298917005714	TOBE domain; Region: TOBE; pfam03459
1298917005715	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
1298917005716	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1298917005717	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1298917005718	NAD binding site [chemical binding]; other site
1298917005719	homodimer interface [polypeptide binding]; other site
1298917005720	active site
1298917005721	substrate binding site [chemical binding]; other site
1298917005722	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1298917005723	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1298917005724	dimer interface [polypeptide binding]; other site
1298917005725	active site
1298917005726	galactokinase; Provisional; Region: PRK05101
1298917005727	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1298917005728	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1298917005729	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1298917005730	active site
1298917005731	catalytic residues [active]
1298917005732	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1298917005733	catalytic core [active]
1298917005734	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1298917005735	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1298917005736	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1298917005737	Walker A/P-loop; other site
1298917005738	ATP binding site [chemical binding]; other site
1298917005739	Q-loop/lid; other site
1298917005740	ABC transporter signature motif; other site
1298917005741	Walker B; other site
1298917005742	D-loop; other site
1298917005743	H-loop/switch region; other site
1298917005744	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1298917005745	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1298917005746	dimer interface [polypeptide binding]; other site
1298917005747	putative PBP binding regions; other site
1298917005748	ABC-ATPase subunit  interface; other site
1298917005749	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1298917005750	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1298917005751	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1298917005752	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1298917005753	active site
1298917005754	catalytic residues [active]
1298917005755	metal binding site [ion binding]; metal-binding site
1298917005756	homodimer binding site [polypeptide binding]; other site
1298917005757	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1298917005758	carboxyltransferase (CT) interaction site; other site
1298917005759	biotinylation site [posttranslational modification]; other site
1298917005760	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1298917005761	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1298917005762	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1298917005763	transmembrane helices; other site
1298917005764	cell density-dependent motility repressor; Provisional; Region: PRK10082
1298917005765	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917005766	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1298917005767	dimerization interface [polypeptide binding]; other site
1298917005768	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917005769	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917005770	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1298917005771	dimerization interface [polypeptide binding]; other site
1298917005772	fumarate hydratase; Provisional; Region: PRK06246
1298917005773	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain [Energy production and conversion]; Region: FumA; COG1838
1298917005774	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1298917005775	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1298917005776	YbgS-like protein; Region: YbgS; pfam13985
1298917005777	zinc transporter ZitB; Provisional; Region: PRK03557
1298917005778	tol-pal system protein YbgF; Provisional; Region: PRK10803
1298917005779	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1298917005780	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1298917005781	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1298917005782	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1298917005783	ligand binding site [chemical binding]; other site
1298917005784	translocation protein TolB; Provisional; Region: tolB; PRK03629
1298917005785	TolB amino-terminal domain; Region: TolB_N; pfam04052
1298917005786	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1298917005787	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1298917005788	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1298917005789	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1298917005790	TolA C-terminal; Region: TolA; pfam06519
1298917005791	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1298917005792	colicin uptake protein TolR; Provisional; Region: PRK11024
1298917005793	colicin uptake protein TolQ; Provisional; Region: PRK10801
1298917005794	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1298917005795	active site
1298917005796	hypothetical protein; Provisional; Region: PRK10588
1298917005797	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
1298917005798	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1298917005799	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1298917005800	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1298917005801	CoA binding domain; Region: CoA_binding; smart00881
1298917005802	CoA-ligase; Region: Ligase_CoA; pfam00549
1298917005803	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1298917005804	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1298917005805	CoA-ligase; Region: Ligase_CoA; pfam00549
1298917005806	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1298917005807	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1298917005808	E3 interaction surface; other site
1298917005809	lipoyl attachment site [posttranslational modification]; other site
1298917005810	e3 binding domain; Region: E3_binding; pfam02817
1298917005811	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1298917005812	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1298917005813	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1298917005814	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1298917005815	SdhC subunit interface [polypeptide binding]; other site
1298917005816	proximal heme binding site [chemical binding]; other site
1298917005817	cardiolipin binding site; other site
1298917005818	Iron-sulfur protein interface; other site
1298917005819	proximal quinone binding site [chemical binding]; other site
1298917005820	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1298917005821	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1298917005822	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1298917005823	dimer interface [polypeptide binding]; other site
1298917005824	active site
1298917005825	citrylCoA binding site [chemical binding]; other site
1298917005826	NADH binding [chemical binding]; other site
1298917005827	cationic pore residues; other site
1298917005828	oxalacetate/citrate binding site [chemical binding]; other site
1298917005829	coenzyme A binding site [chemical binding]; other site
1298917005830	catalytic triad [active]
1298917005831	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1298917005832	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1298917005833	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1298917005834	LamB/YcsF family protein; Provisional; Region: PRK05406
1298917005835	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1298917005836	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1298917005837	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1298917005838	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1298917005839	metal-binding protein; Provisional; Region: PRK10799
1298917005840	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1298917005841	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917005842	putative substrate translocation pore; other site
1298917005843	POT family; Region: PTR2; pfam00854
1298917005844	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1298917005845	DNA photolyase; Region: DNA_photolyase; pfam00875
1298917005846	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1298917005847	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1298917005848	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1298917005849	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1298917005850	sensor protein KdpD; Provisional; Region: PRK10490
1298917005851	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1298917005852	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1298917005853	Ligand Binding Site [chemical binding]; other site
1298917005854	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1298917005855	GAF domain; Region: GAF_3; pfam13492
1298917005856	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917005857	dimer interface [polypeptide binding]; other site
1298917005858	phosphorylation site [posttranslational modification]
1298917005859	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917005860	ATP binding site [chemical binding]; other site
1298917005861	Mg2+ binding site [ion binding]; other site
1298917005862	G-X-G motif; other site
1298917005863	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1298917005864	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917005865	active site
1298917005866	phosphorylation site [posttranslational modification]
1298917005867	intermolecular recognition site; other site
1298917005868	dimerization interface [polypeptide binding]; other site
1298917005869	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917005870	DNA binding site [nucleotide binding]
1298917005871	ornithine decarboxylase; Provisional; Region: PRK13578
1298917005872	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1298917005873	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1298917005874	homodimer interface [polypeptide binding]; other site
1298917005875	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917005876	catalytic residue [active]
1298917005877	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1298917005878	putrescine transporter; Provisional; Region: potE; PRK10655
1298917005879	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
1298917005880	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
1298917005881	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1298917005882	active site
1298917005883	substrate binding site [chemical binding]; other site
1298917005884	metal binding site [ion binding]; metal-binding site
1298917005885	replication initiation regulator SeqA; Provisional; Region: PRK11187
1298917005886	acyl-CoA esterase; Provisional; Region: PRK10673
1298917005887	PGAP1-like protein; Region: PGAP1; pfam07819
1298917005888	LexA regulated protein; Provisional; Region: PRK11675
1298917005889	flavodoxin FldA; Validated; Region: PRK09267
1298917005890	ferric uptake regulator; Provisional; Region: fur; PRK09462
1298917005891	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1298917005892	metal binding site 2 [ion binding]; metal-binding site
1298917005893	putative DNA binding helix; other site
1298917005894	metal binding site 1 [ion binding]; metal-binding site
1298917005895	dimer interface [polypeptide binding]; other site
1298917005896	structural Zn2+ binding site [ion binding]; other site
1298917005897	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917005898	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917005899	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1298917005900	putative dimerization interface [polypeptide binding]; other site
1298917005901	tricarballylate dehydrogenase; Validated; Region: PRK08274
1298917005902	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1298917005903	tricarballylate utilization protein B; Provisional; Region: PRK15033
1298917005904	citrate-proton symporter; Provisional; Region: PRK15075
1298917005905	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917005906	putative substrate translocation pore; other site
1298917005907	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1298917005908	YbfN-like lipoprotein; Region: YbfN; pfam13982
1298917005909	outer membrane porin, OprD family; Region: OprD; pfam03573
1298917005910	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1298917005911	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1298917005912	active site
1298917005913	HIGH motif; other site
1298917005914	nucleotide binding site [chemical binding]; other site
1298917005915	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1298917005916	KMSKS motif; other site
1298917005917	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1298917005918	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1298917005919	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1298917005920	active site
1298917005921	trimer interface [polypeptide binding]; other site
1298917005922	allosteric site; other site
1298917005923	active site lid [active]
1298917005924	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1298917005925	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1298917005926	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1298917005927	active site
1298917005928	dimer interface [polypeptide binding]; other site
1298917005929	MarR family; Region: MarR; pfam01047
1298917005930	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1298917005931	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1298917005932	nucleotide binding site [chemical binding]; other site
1298917005933	UMP phosphatase; Provisional; Region: PRK10444
1298917005934	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917005935	active site
1298917005936	motif I; other site
1298917005937	motif II; other site
1298917005938	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917005939	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1298917005940	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1298917005941	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917005942	FeS/SAM binding site; other site
1298917005943	TRAM domain; Region: TRAM; pfam01938
1298917005944	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1298917005945	PhoH-like protein; Region: PhoH; pfam02562
1298917005946	metal-binding heat shock protein; Provisional; Region: PRK00016
1298917005947	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1298917005948	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1298917005949	Transporter associated domain; Region: CorC_HlyC; smart01091
1298917005950	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1298917005951	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1298917005952	putative active site [active]
1298917005953	catalytic triad [active]
1298917005954	putative dimer interface [polypeptide binding]; other site
1298917005955	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1298917005956	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917005957	substrate binding pocket [chemical binding]; other site
1298917005958	membrane-bound complex binding site; other site
1298917005959	hinge residues; other site
1298917005960	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1298917005961	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917005962	dimer interface [polypeptide binding]; other site
1298917005963	conserved gate region; other site
1298917005964	putative PBP binding loops; other site
1298917005965	ABC-ATPase subunit interface; other site
1298917005966	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1298917005967	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917005968	dimer interface [polypeptide binding]; other site
1298917005969	conserved gate region; other site
1298917005970	putative PBP binding loops; other site
1298917005971	ABC-ATPase subunit interface; other site
1298917005972	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1298917005973	Walker A/P-loop; other site
1298917005974	ATP binding site [chemical binding]; other site
1298917005975	ABC transporter; Region: ABC_tran; pfam00005
1298917005976	Q-loop/lid; other site
1298917005977	ABC transporter signature motif; other site
1298917005978	Walker B; other site
1298917005979	D-loop; other site
1298917005980	H-loop/switch region; other site
1298917005981	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1298917005982	active site
1298917005983	tetramer interface [polypeptide binding]; other site
1298917005984	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
1298917005985	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
1298917005986	nucleotide binding site [chemical binding]; other site
1298917005987	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1298917005988	SBD interface [polypeptide binding]; other site
1298917005989	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
1298917005990	HSP70 interaction site [polypeptide binding]; other site
1298917005991	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1298917005992	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1298917005993	HSP70 interaction site [polypeptide binding]; other site
1298917005994	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1298917005995	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1298917005996	Sel1-like repeats; Region: SEL1; smart00671
1298917005997	Sel1-like repeats; Region: SEL1; smart00671
1298917005998	Sel1-like repeats; Region: SEL1; smart00671
1298917005999	Sel1-like repeats; Region: SEL1; smart00671
1298917006000	Sel1-like repeats; Region: SEL1; smart00671
1298917006001	hypothetical protein; Provisional; Region: PRK11032
1298917006002	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1298917006003	Propionate catabolism activator; Region: PrpR_N; pfam06506
1298917006004	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1298917006005	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917006006	Walker A motif; other site
1298917006007	ATP binding site [chemical binding]; other site
1298917006008	Walker B motif; other site
1298917006009	arginine finger; other site
1298917006010	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
1298917006011	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1298917006012	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1298917006013	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1298917006014	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1298917006015	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1298917006016	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1298917006017	active site
1298917006018	(T/H)XGH motif; other site
1298917006019	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
1298917006020	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917006021	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917006022	homodimer interface [polypeptide binding]; other site
1298917006023	catalytic residue [active]
1298917006024	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1298917006025	catalytic core [active]
1298917006026	ribosome-associated protein; Provisional; Region: PRK11538
1298917006027	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1298917006028	penicillin-binding protein 2; Provisional; Region: PRK10795
1298917006029	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1298917006030	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1298917006031	cell wall shape-determining protein; Provisional; Region: PRK10794
1298917006032	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1298917006033	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1298917006034	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1298917006035	hypothetical protein; Provisional; Region: PRK04998
1298917006036	lipoate-protein ligase B; Provisional; Region: PRK14342
1298917006037	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1298917006038	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917006039	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1298917006040	substrate binding pocket [chemical binding]; other site
1298917006041	dimerization interface [polypeptide binding]; other site
1298917006042	lipoyl synthase; Provisional; Region: PRK05481
1298917006043	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917006044	FeS/SAM binding site; other site
1298917006045	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1298917006046	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1298917006047	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1298917006048	putative active site [active]
1298917006049	catalytic triad [active]
1298917006050	putative dimer interface [polypeptide binding]; other site
1298917006051	chromosome condensation membrane protein; Provisional; Region: PRK14196
1298917006052	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1298917006053	DNA-binding site [nucleotide binding]; DNA binding site
1298917006054	RNA-binding motif; other site
1298917006055	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1298917006056	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1298917006057	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1298917006058	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
1298917006059	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917006060	active site
1298917006061	phosphorylation site [posttranslational modification]
1298917006062	intermolecular recognition site; other site
1298917006063	dimerization interface [polypeptide binding]; other site
1298917006064	Transcriptional regulator; Region: CitT; pfam12431
1298917006065	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
1298917006066	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1298917006067	putative active site [active]
1298917006068	heme pocket [chemical binding]; other site
1298917006069	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917006070	ATP binding site [chemical binding]; other site
1298917006071	Mg2+ binding site [ion binding]; other site
1298917006072	G-X-G motif; other site
1298917006073	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1298917006074	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1298917006075	putative active site [active]
1298917006076	(T/H)XGH motif; other site
1298917006077	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1298917006078	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1298917006079	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1298917006080	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
1298917006081	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1298917006082	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1298917006083	transmembrane helices; other site
1298917006084	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1298917006085	B1 nucleotide binding pocket [chemical binding]; other site
1298917006086	B2 nucleotide binding pocket [chemical binding]; other site
1298917006087	CAS motifs; other site
1298917006088	active site
1298917006089	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1298917006090	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1298917006091	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1298917006092	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1298917006093	NAD binding site [chemical binding]; other site
1298917006094	catalytic Zn binding site [ion binding]; other site
1298917006095	structural Zn binding site [ion binding]; other site
1298917006096	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1298917006097	Ligand Binding Site [chemical binding]; other site
1298917006098	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1298917006099	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1298917006100	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1298917006101	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1298917006102	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
1298917006103	putative [4Fe-4S] binding site [ion binding]; other site
1298917006104	putative molybdopterin cofactor binding site [chemical binding]; other site
1298917006105	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
1298917006106	molybdopterin cofactor binding site; other site
1298917006107	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1298917006108	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1298917006109	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1298917006110	catalytic residue [active]
1298917006111	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1298917006112	catalytic residues [active]
1298917006113	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1298917006114	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917006115	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1298917006116	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1298917006117	dimer interface [polypeptide binding]; other site
1298917006118	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1298917006119	catalytic triad [active]
1298917006120	peroxidatic and resolving cysteines [active]
1298917006121	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1298917006122	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1298917006123	dimerization domain [polypeptide binding]; other site
1298917006124	dimer interface [polypeptide binding]; other site
1298917006125	catalytic residues [active]
1298917006126	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1298917006127	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917006128	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1298917006129	dimerization interface [polypeptide binding]; other site
1298917006130	methionine aminotransferase; Validated; Region: PRK09082
1298917006131	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917006132	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917006133	homodimer interface [polypeptide binding]; other site
1298917006134	catalytic residue [active]
1298917006135	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1298917006136	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1298917006137	putative active site [active]
1298917006138	metal binding site [ion binding]; metal-binding site
1298917006139	Uncharacterized small protein [Function unknown]; Region: COG2879
1298917006140	carbon starvation protein A; Provisional; Region: PRK15015
1298917006141	Carbon starvation protein CstA; Region: CstA; pfam02554
1298917006142	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1298917006143	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1298917006144	CoenzymeA binding site [chemical binding]; other site
1298917006145	subunit interaction site [polypeptide binding]; other site
1298917006146	PHB binding site; other site
1298917006147	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1298917006148	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1298917006149	putative NAD(P) binding site [chemical binding]; other site
1298917006150	active site
1298917006151	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1298917006152	hydrophobic substrate binding pocket; other site
1298917006153	Isochorismatase family; Region: Isochorismatase; pfam00857
1298917006154	active site
1298917006155	conserved cis-peptide bond; other site
1298917006156	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1298917006157	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
1298917006158	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1298917006159	siderophore binding site; other site
1298917006160	enterobactin exporter EntS; Provisional; Region: PRK10489
1298917006161	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917006162	putative substrate translocation pore; other site
1298917006163	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1298917006164	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1298917006165	ABC-ATPase subunit  interface; other site
1298917006166	dimer interface [polypeptide binding]; other site
1298917006167	putative PBP binding regions; other site
1298917006168	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1298917006169	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1298917006170	Walker A/P-loop; other site
1298917006171	ATP binding site [chemical binding]; other site
1298917006172	Q-loop/lid; other site
1298917006173	ABC transporter signature motif; other site
1298917006174	Walker B; other site
1298917006175	D-loop; other site
1298917006176	H-loop/switch region; other site
1298917006177	LPS O-antigen length regulator; Provisional; Region: PRK10381
1298917006178	Chain length determinant protein; Region: Wzz; pfam02706
1298917006179	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
1298917006180	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1298917006181	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1298917006182	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1298917006183	outer membrane receptor FepA; Provisional; Region: PRK13524
1298917006184	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1298917006185	N-terminal plug; other site
1298917006186	ligand-binding site [chemical binding]; other site
1298917006187	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
1298917006188	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1298917006189	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1298917006190	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1298917006191	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917006192	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1298917006193	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917006194	hypothetical protein; Provisional; Region: PRK10250
1298917006195	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1298917006196	dimer interface [polypeptide binding]; other site
1298917006197	FMN binding site [chemical binding]; other site
1298917006198	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1298917006199	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1298917006200	active site
1298917006201	oxyanion hole [active]
1298917006202	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1298917006203	catalytic triad [active]
1298917006204	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1298917006205	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1298917006206	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1298917006207	phenylalanine transporter; Provisional; Region: PRK10249
1298917006208	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
1298917006209	Predicted membrane protein [Function unknown]; Region: COG3059
1298917006210	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1298917006211	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
1298917006212	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917006213	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1298917006214	Cupin; Region: Cupin_6; pfam12852
1298917006215	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1298917006216	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917006217	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917006218	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
1298917006219	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917006220	ATP binding site [chemical binding]; other site
1298917006221	Mg2+ binding site [ion binding]; other site
1298917006222	G-X-G motif; other site
1298917006223	Predicted membrane protein [Function unknown]; Region: COG2246
1298917006224	GtrA-like protein; Region: GtrA; pfam04138
1298917006225	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1298917006226	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1298917006227	Ligand binding site; other site
1298917006228	Putative Catalytic site; other site
1298917006229	DXD motif; other site
1298917006230	Integrase core domain; Region: rve; pfam00665
1298917006231	Integrase core domain; Region: rve_2; pfam13333
1298917006232	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
1298917006233	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917006234	DNA binding residues [nucleotide binding]
1298917006235	dimerization interface [polypeptide binding]; other site
1298917006236	transcriptional regulator FimZ; Provisional; Region: PRK09935
1298917006237	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917006238	active site
1298917006239	phosphorylation site [posttranslational modification]
1298917006240	intermolecular recognition site; other site
1298917006241	dimerization interface [polypeptide binding]; other site
1298917006242	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917006243	DNA binding residues [nucleotide binding]
1298917006244	dimerization interface [polypeptide binding]; other site
1298917006245	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
1298917006246	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
1298917006247	outer membrane usher protein FimD; Provisional; Region: PRK15198
1298917006248	PapC N-terminal domain; Region: PapC_N; pfam13954
1298917006249	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1298917006250	PapC C-terminal domain; Region: PapC_C; pfam13953
1298917006251	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1298917006252	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917006253	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917006254	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1298917006255	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1298917006256	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1298917006257	homodimer interface [polypeptide binding]; other site
1298917006258	NADP binding site [chemical binding]; other site
1298917006259	substrate binding site [chemical binding]; other site
1298917006260	ribosome-associated protein; Provisional; Region: PRK11507
1298917006261	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1298917006262	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4727
1298917006263	Uncharacterized protein conserved in bacteria (DUF2145); Region: DUF2145; pfam09916
1298917006264	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1298917006265	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1298917006266	active site
1298917006267	HIGH motif; other site
1298917006268	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1298917006269	KMSKS motif; other site
1298917006270	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1298917006271	tRNA binding surface [nucleotide binding]; other site
1298917006272	anticodon binding site; other site
1298917006273	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1298917006274	substrate binding site [chemical binding]; other site
1298917006275	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1298917006276	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1298917006277	putative active site [active]
1298917006278	putative metal binding site [ion binding]; other site
1298917006279	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1298917006280	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1298917006281	ATP-grasp domain; Region: ATP-grasp; pfam02222
1298917006282	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1298917006283	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1298917006284	putative substrate binding site [chemical binding]; other site
1298917006285	nucleotide binding site [chemical binding]; other site
1298917006286	nucleotide binding site [chemical binding]; other site
1298917006287	homodimer interface [polypeptide binding]; other site
1298917006288	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1298917006289	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1298917006290	membrane protein FdrA; Validated; Region: PRK06091
1298917006291	CoA binding domain; Region: CoA_binding; pfam02629
1298917006292	CoA-ligase; Region: Ligase_CoA; pfam00549
1298917006293	allantoate amidohydrolase; Region: AllC; TIGR03176
1298917006294	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1298917006295	active site
1298917006296	metal binding site [ion binding]; metal-binding site
1298917006297	dimer interface [polypeptide binding]; other site
1298917006298	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
1298917006299	Mif2/CENP-C like; Region: Mif2; pfam11699
1298917006300	Cupin domain; Region: Cupin_2; pfam07883
1298917006301	glycerate kinase II; Provisional; Region: PRK09932
1298917006302	allantoinase; Provisional; Region: PRK08044
1298917006303	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
1298917006304	active site
1298917006305	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily, YbbW-like; solute-binding domain; Region: SLC-NCS1sbd_YbbW-like; cd11485
1298917006306	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1298917006307	Na binding site [ion binding]; other site
1298917006308	putative substrate binding site [chemical binding]; other site
1298917006309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917006310	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1298917006311	putative substrate translocation pore; other site
1298917006312	tartronate semialdehyde reductase; Provisional; Region: PRK15059
1298917006313	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1298917006314	hydroxypyruvate isomerase; Provisional; Region: PRK09997
1298917006315	glyoxylate carboligase; Provisional; Region: PRK11269
1298917006316	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1298917006317	PYR/PP interface [polypeptide binding]; other site
1298917006318	dimer interface [polypeptide binding]; other site
1298917006319	TPP binding site [chemical binding]; other site
1298917006320	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1298917006321	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
1298917006322	TPP-binding site [chemical binding]; other site
1298917006323	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
1298917006324	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1298917006325	Bacterial transcriptional regulator; Region: IclR; pfam01614
1298917006326	ureidoglycolate hydrolase; Provisional; Region: PRK03606
1298917006327	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
1298917006328	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1298917006329	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917006330	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1298917006331	dimerization interface [polypeptide binding]; other site
1298917006332	Predicted ATPase [General function prediction only]; Region: COG2603
1298917006333	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1298917006334	active site residue [active]
1298917006335	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917006336	dimer interface [polypeptide binding]; other site
1298917006337	conserved gate region; other site
1298917006338	ABC-ATPase subunit interface; other site
1298917006339	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1298917006340	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1298917006341	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1298917006342	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1298917006343	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1298917006344	FtsX-like permease family; Region: FtsX; pfam02687
1298917006345	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1298917006346	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1298917006347	Walker A/P-loop; other site
1298917006348	ATP binding site [chemical binding]; other site
1298917006349	Q-loop/lid; other site
1298917006350	ABC transporter signature motif; other site
1298917006351	Walker B; other site
1298917006352	D-loop; other site
1298917006353	H-loop/switch region; other site
1298917006354	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1298917006355	active site
1298917006356	catalytic triad [active]
1298917006357	oxyanion hole [active]
1298917006358	switch loop; other site
1298917006359	oxidoreductase; Provisional; Region: PRK08017
1298917006360	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1298917006361	NADP binding site [chemical binding]; other site
1298917006362	active site
1298917006363	steroid binding site; other site
1298917006364	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1298917006365	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1298917006366	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1298917006367	Walker A/P-loop; other site
1298917006368	ATP binding site [chemical binding]; other site
1298917006369	Q-loop/lid; other site
1298917006370	ABC transporter signature motif; other site
1298917006371	Walker B; other site
1298917006372	D-loop; other site
1298917006373	H-loop/switch region; other site
1298917006374	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1298917006375	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1298917006376	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1298917006377	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1298917006378	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1298917006379	DNA binding residues [nucleotide binding]
1298917006380	dimer interface [polypeptide binding]; other site
1298917006381	copper binding site [ion binding]; other site
1298917006382	copper exporting ATPase; Provisional; Region: copA; PRK10671
1298917006383	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1298917006384	metal-binding site [ion binding]
1298917006385	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1298917006386	metal-binding site [ion binding]
1298917006387	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1298917006388	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917006389	motif II; other site
1298917006390	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1298917006391	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
1298917006392	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1298917006393	putative deacylase active site [active]
1298917006394	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1298917006395	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1298917006396	active site
1298917006397	metal binding site [ion binding]; metal-binding site
1298917006398	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1298917006399	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917006400	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1298917006401	putative substrate translocation pore; other site
1298917006402	putative cation:proton antiport protein; Provisional; Region: PRK10669
1298917006403	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1298917006404	TrkA-N domain; Region: TrkA_N; pfam02254
1298917006405	inosine/guanosine kinase; Provisional; Region: PRK15074
1298917006406	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1298917006407	ferrochelatase; Reviewed; Region: hemH; PRK00035
1298917006408	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1298917006409	C-terminal domain interface [polypeptide binding]; other site
1298917006410	active site
1298917006411	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1298917006412	active site
1298917006413	N-terminal domain interface [polypeptide binding]; other site
1298917006414	adenylate kinase; Reviewed; Region: adk; PRK00279
1298917006415	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1298917006416	AMP-binding site [chemical binding]; other site
1298917006417	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1298917006418	heat shock protein 90; Provisional; Region: PRK05218
1298917006419	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917006420	ATP binding site [chemical binding]; other site
1298917006421	Mg2+ binding site [ion binding]; other site
1298917006422	G-X-G motif; other site
1298917006423	recombination protein RecR; Reviewed; Region: recR; PRK00076
1298917006424	RecR protein; Region: RecR; pfam02132
1298917006425	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1298917006426	putative active site [active]
1298917006427	putative metal-binding site [ion binding]; other site
1298917006428	tetramer interface [polypeptide binding]; other site
1298917006429	hypothetical protein; Validated; Region: PRK00153
1298917006430	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1298917006431	active site
1298917006432	hypothetical protein; Provisional; Region: PRK10527
1298917006433	primosomal replication protein N''; Provisional; Region: PRK10093
1298917006434	hypothetical protein; Provisional; Region: PRK11038
1298917006435	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1298917006436	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1298917006437	hypothetical protein; Provisional; Region: PRK11281
1298917006438	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1298917006439	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
1298917006440	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1298917006441	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1298917006442	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917006443	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1298917006444	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1298917006445	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917006446	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1298917006447	Protein export membrane protein; Region: SecD_SecF; cl14618
1298917006448	Protein export membrane protein; Region: SecD_SecF; cl14618
1298917006449	Hha toxicity attenuator; Provisional; Region: PRK10667
1298917006450	gene expression modulator; Provisional; Region: PRK10945
1298917006451	maltose O-acetyltransferase; Provisional; Region: PRK10092
1298917006452	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1298917006453	active site
1298917006454	substrate binding site [chemical binding]; other site
1298917006455	trimer interface [polypeptide binding]; other site
1298917006456	CoA binding site [chemical binding]; other site
1298917006457	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1298917006458	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1298917006459	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1298917006460	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1298917006461	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1298917006462	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917006463	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1298917006464	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1298917006465	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1298917006466	active site
1298917006467	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1298917006468	catalytic triad [active]
1298917006469	dimer interface [polypeptide binding]; other site
1298917006470	ammonium transporter; Provisional; Region: PRK10666
1298917006471	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1298917006472	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1298917006473	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1298917006474	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1298917006475	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917006476	Walker A/P-loop; other site
1298917006477	ATP binding site [chemical binding]; other site
1298917006478	Q-loop/lid; other site
1298917006479	ABC transporter signature motif; other site
1298917006480	Walker B; other site
1298917006481	D-loop; other site
1298917006482	H-loop/switch region; other site
1298917006483	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1298917006484	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1298917006485	putative DNA binding site [nucleotide binding]; other site
1298917006486	putative Zn2+ binding site [ion binding]; other site
1298917006487	AsnC family; Region: AsnC_trans_reg; pfam01037
1298917006488	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1298917006489	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1298917006490	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1298917006491	catalytic residue [active]
1298917006492	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1298917006493	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1298917006494	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1298917006495	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1298917006496	Ligand Binding Site [chemical binding]; other site
1298917006497	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1298917006498	active site
1298917006499	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1298917006500	periplasmic folding chaperone; Provisional; Region: PRK10788
1298917006501	SurA N-terminal domain; Region: SurA_N_3; cl07813
1298917006502	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1298917006503	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1298917006504	IHF dimer interface [polypeptide binding]; other site
1298917006505	IHF - DNA interface [nucleotide binding]; other site
1298917006506	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1298917006507	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1298917006508	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1298917006509	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917006510	Walker A motif; other site
1298917006511	ATP binding site [chemical binding]; other site
1298917006512	Walker B motif; other site
1298917006513	arginine finger; other site
1298917006514	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1298917006515	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1298917006516	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1298917006517	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917006518	Walker A motif; other site
1298917006519	ATP binding site [chemical binding]; other site
1298917006520	Walker B motif; other site
1298917006521	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1298917006522	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1298917006523	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1298917006524	oligomer interface [polypeptide binding]; other site
1298917006525	active site residues [active]
1298917006526	trigger factor; Provisional; Region: tig; PRK01490
1298917006527	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1298917006528	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1298917006529	transcriptional regulator BolA; Provisional; Region: PRK11628
1298917006530	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1298917006531	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917006532	putative substrate translocation pore; other site
1298917006533	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1298917006534	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1298917006535	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1298917006536	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1298917006537	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1298917006538	D-pathway; other site
1298917006539	Putative ubiquinol binding site [chemical binding]; other site
1298917006540	Low-spin heme (heme b) binding site [chemical binding]; other site
1298917006541	Putative water exit pathway; other site
1298917006542	Binuclear center (heme o3/CuB) [ion binding]; other site
1298917006543	K-pathway; other site
1298917006544	Putative proton exit pathway; other site
1298917006545	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1298917006546	Subunit I/III interface [polypeptide binding]; other site
1298917006547	Subunit III/IV interface [polypeptide binding]; other site
1298917006548	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1298917006549	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1298917006550	UbiA prenyltransferase family; Region: UbiA; pfam01040
1298917006551	Sel1-like repeats; Region: SEL1; smart00671
1298917006552	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1298917006553	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1298917006554	Sel1-like repeats; Region: SEL1; smart00671
1298917006555	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917006556	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1298917006557	putative substrate translocation pore; other site
1298917006558	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1298917006559	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1298917006560	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1298917006561	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1298917006562	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1298917006563	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1298917006564	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1298917006565	conserved cys residue [active]
1298917006566	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
1298917006567	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917006568	motif II; other site
1298917006569	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
1298917006570	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1298917006571	catalytic residue [active]
1298917006572	transcriptional regulator protein; Region: phnR; TIGR03337
1298917006573	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917006574	DNA-binding site [nucleotide binding]; DNA binding site
1298917006575	UTRA domain; Region: UTRA; pfam07702
1298917006576	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
1298917006577	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1298917006578	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
1298917006579	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917006580	Walker A/P-loop; other site
1298917006581	ATP binding site [chemical binding]; other site
1298917006582	Q-loop/lid; other site
1298917006583	ABC transporter signature motif; other site
1298917006584	Walker B; other site
1298917006585	D-loop; other site
1298917006586	H-loop/switch region; other site
1298917006587	TOBE domain; Region: TOBE_2; pfam08402
1298917006588	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1298917006589	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917006590	dimer interface [polypeptide binding]; other site
1298917006591	conserved gate region; other site
1298917006592	putative PBP binding loops; other site
1298917006593	ABC-ATPase subunit interface; other site
1298917006594	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1298917006595	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1298917006596	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1298917006597	Ligand Binding Site [chemical binding]; other site
1298917006598	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1298917006599	active site residue [active]
1298917006600	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1298917006601	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1298917006602	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1298917006603	substrate binding pocket [chemical binding]; other site
1298917006604	chain length determination region; other site
1298917006605	substrate-Mg2+ binding site; other site
1298917006606	catalytic residues [active]
1298917006607	aspartate-rich region 1; other site
1298917006608	active site lid residues [active]
1298917006609	aspartate-rich region 2; other site
1298917006610	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1298917006611	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1298917006612	TPP-binding site; other site
1298917006613	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1298917006614	PYR/PP interface [polypeptide binding]; other site
1298917006615	dimer interface [polypeptide binding]; other site
1298917006616	TPP binding site [chemical binding]; other site
1298917006617	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1298917006618	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1298917006619	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1298917006620	active site
1298917006621	catalytic tetrad [active]
1298917006622	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1298917006623	tetramer interfaces [polypeptide binding]; other site
1298917006624	binuclear metal-binding site [ion binding]; other site
1298917006625	thiamine monophosphate kinase; Provisional; Region: PRK05731
1298917006626	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1298917006627	ATP binding site [chemical binding]; other site
1298917006628	dimerization interface [polypeptide binding]; other site
1298917006629	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1298917006630	putative RNA binding site [nucleotide binding]; other site
1298917006631	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1298917006632	homopentamer interface [polypeptide binding]; other site
1298917006633	active site
1298917006634	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1298917006635	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1298917006636	catalytic motif [active]
1298917006637	Zn binding site [ion binding]; other site
1298917006638	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1298917006639	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1298917006640	ATP cone domain; Region: ATP-cone; pfam03477
1298917006641	hypothetical protein; Provisional; Region: PRK11530
1298917006642	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1298917006643	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1298917006644	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1298917006645	active site
1298917006646	Predicted transcriptional regulator [Transcription]; Region: COG2378
1298917006647	HTH domain; Region: HTH_11; pfam08279
1298917006648	WYL domain; Region: WYL; pfam13280
1298917006649	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
1298917006650	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1298917006651	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1298917006652	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1298917006653	Protein export membrane protein; Region: SecD_SecF; pfam02355
1298917006654	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1298917006655	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1298917006656	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1298917006657	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1298917006658	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1298917006659	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1298917006660	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1298917006661	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1298917006662	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1298917006663	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1298917006664	peroxidase; Provisional; Region: PRK15000
1298917006665	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1298917006666	dimer interface [polypeptide binding]; other site
1298917006667	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1298917006668	catalytic triad [active]
1298917006669	peroxidatic and resolving cysteines [active]
1298917006670	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1298917006671	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1298917006672	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1298917006673	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1298917006674	putative active site [active]
1298917006675	heme pocket [chemical binding]; other site
1298917006676	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917006677	dimer interface [polypeptide binding]; other site
1298917006678	phosphorylation site [posttranslational modification]
1298917006679	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917006680	ATP binding site [chemical binding]; other site
1298917006681	Mg2+ binding site [ion binding]; other site
1298917006682	G-X-G motif; other site
1298917006683	transcriptional regulator PhoB; Provisional; Region: PRK10161
1298917006684	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917006685	active site
1298917006686	phosphorylation site [posttranslational modification]
1298917006687	intermolecular recognition site; other site
1298917006688	dimerization interface [polypeptide binding]; other site
1298917006689	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917006690	DNA binding site [nucleotide binding]
1298917006691	exonuclease subunit SbcD; Provisional; Region: PRK10966
1298917006692	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1298917006693	active site
1298917006694	metal binding site [ion binding]; metal-binding site
1298917006695	DNA binding site [nucleotide binding]
1298917006696	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1298917006697	MFS transport protein AraJ; Provisional; Region: PRK10091
1298917006698	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917006699	putative substrate translocation pore; other site
1298917006700	fructokinase; Reviewed; Region: PRK09557
1298917006701	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1298917006702	nucleotide binding site [chemical binding]; other site
1298917006703	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
1298917006704	hypothetical protein; Provisional; Region: PRK10579
1298917006705	hypothetical protein; Provisional; Region: PRK10481
1298917006706	hypothetical protein; Provisional; Region: PRK10380
1298917006707	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1298917006708	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1298917006709	ADP binding site [chemical binding]; other site
1298917006710	magnesium binding site [ion binding]; other site
1298917006711	putative shikimate binding site; other site
1298917006712	hypothetical protein; Validated; Region: PRK00124
1298917006713	hypothetical protein; Provisional; Region: PRK11505
1298917006714	psiF repeat; Region: PsiF_repeat; pfam07769
1298917006715	psiF repeat; Region: PsiF_repeat; pfam07769
1298917006716	anti-RssB factor; Provisional; Region: PRK10244
1298917006717	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
1298917006718	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
1298917006719	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1298917006720	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1298917006721	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1298917006722	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
1298917006723	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
1298917006724	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1298917006725	microcin B17 transporter; Reviewed; Region: PRK11098
1298917006726	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1298917006727	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1298917006728	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1298917006729	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1298917006730	ligand binding site [chemical binding]; other site
1298917006731	flexible hinge region; other site
1298917006732	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
1298917006733	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1298917006734	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1298917006735	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1298917006736	dimer interface [polypeptide binding]; other site
1298917006737	active site
1298917006738	Schiff base residues; other site
1298917006739	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1298917006740	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1298917006741	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1298917006742	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
1298917006743	dimer interface [polypeptide binding]; other site
1298917006744	active site
1298917006745	citrylCoA binding site [chemical binding]; other site
1298917006746	oxalacetate/citrate binding site [chemical binding]; other site
1298917006747	coenzyme A binding site [chemical binding]; other site
1298917006748	catalytic triad [active]
1298917006749	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1298917006750	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1298917006751	tetramer interface [polypeptide binding]; other site
1298917006752	active site
1298917006753	Mg2+/Mn2+ binding site [ion binding]; other site
1298917006754	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1298917006755	Propionate catabolism activator; Region: PrpR_N; pfam06506
1298917006756	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917006757	Walker A motif; other site
1298917006758	ATP binding site [chemical binding]; other site
1298917006759	Walker B motif; other site
1298917006760	arginine finger; other site
1298917006761	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1298917006762	hypothetical protein; Provisional; Region: PRK09929
1298917006763	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
1298917006764	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1298917006765	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1298917006766	N-terminal plug; other site
1298917006767	ligand-binding site [chemical binding]; other site
1298917006768	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1298917006769	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1298917006770	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1298917006771	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1298917006772	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
1298917006773	VRR-NUC domain; Region: VRR_NUC; pfam08774
1298917006774	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1298917006775	ATP binding site [chemical binding]; other site
1298917006776	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1298917006777	putative sialic acid transporter; Region: 2A0112; TIGR00891
1298917006778	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917006779	putative substrate translocation pore; other site
1298917006780	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1298917006781	metal-binding site [ion binding]
1298917006782	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1298917006783	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1298917006784	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917006785	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1298917006786	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1298917006787	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1298917006788	DNA binding residues [nucleotide binding]
1298917006789	dimerization interface [polypeptide binding]; other site
1298917006790	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1298917006791	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1298917006792	DNA binding site [nucleotide binding]
1298917006793	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1298917006794	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917006795	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1298917006796	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917006797	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917006798	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
1298917006799	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917006800	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917006801	transcriptional activator TtdR; Provisional; Region: PRK09801
1298917006802	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917006803	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1298917006804	putative effector binding pocket; other site
1298917006805	putative dimerization interface [polypeptide binding]; other site
1298917006806	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1298917006807	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1298917006808	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1298917006809	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1298917006810	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1298917006811	substrate binding site [chemical binding]; other site
1298917006812	ligand binding site [chemical binding]; other site
1298917006813	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1298917006814	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917006815	putative substrate translocation pore; other site
1298917006816	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
1298917006817	Transposase; Region: HTH_Tnp_1; cl17663
1298917006818	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1298917006819	HTH-like domain; Region: HTH_21; pfam13276
1298917006820	Predicted membrane protein [Function unknown]; Region: COG2246
1298917006821	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1298917006822	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1298917006823	Ligand binding site; other site
1298917006824	Putative Catalytic site; other site
1298917006825	DXD motif; other site
1298917006826	O-antigen conversion protein C; Region: PHA01514
1298917006827	Head binding; Region: Head_binding; pfam09008
1298917006828	Salmonella phage P22 tail-spike; Region: PhageP22-tail; pfam09251
1298917006829	Mnt; Region: mnt; PHA01513
1298917006830	Arc-like DNA binding domain; Region: Arc; pfam03869
1298917006831	Regulatory protein Mnt; Region: Repressor_Mnt; pfam11423
1298917006832	Protein of unknown function (DUF2824); Region: DUF2824; pfam11039
1298917006833	Phage stabilisation protein; Region: Phage_stabilise; pfam11134
1298917006834	P22 tail accessory factor; Region: P22_Tail-4; pfam11650
1298917006835	coat protein; Region: PHA01511
1298917006836	P22 coat protein - gene protein 5; Region: P22_CoatProtein; pfam11651
1298917006837	Bacteriophage, scaffolding protein; Region: Phage-scaffold; pfam09306
1298917006838	Terminase-like family; Region: Terminase_6; pfam03237
1298917006839	Bacteriophage terminase large (ATPase) subunit and inactivated derivatives [General function prediction only]; Region: COG5565
1298917006840	hypothetical protein; Region: PHA00527
1298917006841	hypothetical protein; Region: PHA00780
1298917006842	KilA-N domain; Region: KilA-N; pfam04383
1298917006843	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1298917006844	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1298917006845	catalytic residues [active]
1298917006846	Antitermination protein; Region: Antiterm; pfam03589
1298917006847	Antitermination protein; Region: Antiterm; pfam03589
1298917006848	Phage NinH protein; Region: Phage_NinH; pfam06322
1298917006849	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1298917006850	NinF protein; Region: NinF; pfam05810
1298917006851	hypothetical protein; Region: PHA01519
1298917006852	NINE Protein; Region: NinE; pfam05322
1298917006853	NinB protein; Region: NinB; pfam05772
1298917006854	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1298917006855	DnaB-like helicase C terminal domain; Region: DnaB_C; pfam03796
1298917006856	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1298917006857	Walker A motif; other site
1298917006858	ATP binding site [chemical binding]; other site
1298917006859	Walker B motif; other site
1298917006860	DNA binding loops [nucleotide binding]
1298917006861	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1298917006862	Bacteriophage CII protein; Region: Phage_CII; pfam05269
1298917006863	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
1298917006864	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917006865	non-specific DNA binding site [nucleotide binding]; other site
1298917006866	Predicted transcriptional regulator [Transcription]; Region: COG2932
1298917006867	salt bridge; other site
1298917006868	sequence-specific DNA binding site [nucleotide binding]; other site
1298917006869	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1298917006870	Catalytic site [active]
1298917006871	P63C domain; Region: P63C; pfam10546
1298917006872	Superinfection exclusion protein B; Region: SieB; pfam14163
1298917006873	Antirestriction protein Ral; Region: Ral; pfam11058
1298917006874	hypothetical protein; Region: PHA01516
1298917006875	Lambda Phage CIII; Region: Lambda_CIII; pfam02061
1298917006876	Rad52/22 family double-strand break repair protein; Region: Rad52_Rad22; cl01936
1298917006877	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1298917006878	Protein of unknown function (DUF2856); Region: DUF2856; pfam11043
1298917006879	Protein of unknown function (DUF2737); Region: DUF2737; pfam10930
1298917006880	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1298917006881	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1298917006882	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
1298917006883	Helix-turn-helix domain; Region: HTH_17; pfam12728
1298917006884	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1298917006885	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
1298917006886	Int/Topo IB signature motif; other site
1298917006887	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1298917006888	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1298917006889	putative catalytic cysteine [active]
1298917006890	gamma-glutamyl kinase; Provisional; Region: PRK05429
1298917006891	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1298917006892	nucleotide binding site [chemical binding]; other site
1298917006893	homotetrameric interface [polypeptide binding]; other site
1298917006894	putative phosphate binding site [ion binding]; other site
1298917006895	putative allosteric binding site; other site
1298917006896	PUA domain; Region: PUA; pfam01472
1298917006897	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1298917006898	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1298917006899	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1298917006900	active site
1298917006901	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1298917006902	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1298917006903	metal binding site [ion binding]; metal-binding site
1298917006904	dimer interface [polypeptide binding]; other site
1298917006905	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1298917006906	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1298917006907	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1298917006908	active site
1298917006909	DNA polymerase IV; Validated; Region: PRK02406
1298917006910	DNA binding site [nucleotide binding]
1298917006911	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1298917006912	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1298917006913	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1298917006914	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1298917006915	putative active site [active]
1298917006916	putative dimer interface [polypeptide binding]; other site
1298917006917	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1298917006918	dimer interface [polypeptide binding]; other site
1298917006919	active site
1298917006920	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1298917006921	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1298917006922	active site
1298917006923	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1298917006924	C-N hydrolase family amidase; Provisional; Region: PRK10438
1298917006925	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1298917006926	putative active site [active]
1298917006927	catalytic triad [active]
1298917006928	dimer interface [polypeptide binding]; other site
1298917006929	multimer interface [polypeptide binding]; other site
1298917006930	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1298917006931	dimer interface [polypeptide binding]; other site
1298917006932	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1298917006933	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917006934	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917006935	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1298917006936	dimerization interface [polypeptide binding]; other site
1298917006937	PerC transcriptional activator; Region: PerC; pfam06069
1298917006938	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1298917006939	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
1298917006940	putative active site [active]
1298917006941	putative metal binding site [ion binding]; other site
1298917006942	putative pilin structural protein SafD; Provisional; Region: PRK15222
1298917006943	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
1298917006944	PapC N-terminal domain; Region: PapC_N; pfam13954
1298917006945	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1298917006946	PapC C-terminal domain; Region: PapC_C; pfam13953
1298917006947	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
1298917006948	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917006949	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917006950	Saf-pilin pilus formation protein SafA; Provisional; Region: PRK15221
1298917006951	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1298917006952	Integrase core domain; Region: rve_3; pfam13683
1298917006953	Transposase; Region: HTH_Tnp_1; cl17663
1298917006954	Protein of unknown function (DUF4019); Region: DUF4019; pfam13211
1298917006955	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1298917006956	RHS protein; Region: RHS; pfam03527
1298917006957	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1298917006958	Domain of unknown function (DUF3554); Region: DUF3554; pfam12074
1298917006959	Predicted GTPase [General function prediction only]; Region: COG3596
1298917006960	YfjP GTPase; Region: YfjP; cd11383
1298917006961	G1 box; other site
1298917006962	GTP/Mg2+ binding site [chemical binding]; other site
1298917006963	Switch I region; other site
1298917006964	G2 box; other site
1298917006965	Switch II region; other site
1298917006966	G3 box; other site
1298917006967	G4 box; other site
1298917006968	G5 box; other site
1298917006969	Stage III sporulation protein D; Region: SpoIIID; cl17560
1298917006970	WYL domain; Region: WYL; cl14852
1298917006971	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
1298917006972	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1298917006973	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1298917006974	Antirestriction protein; Region: Antirestrict; pfam03230
1298917006975	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1298917006976	MPN+ (JAMM) motif; other site
1298917006977	Zinc-binding site [ion binding]; other site
1298917006978	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1298917006979	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1298917006980	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1298917006981	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1298917006982	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1298917006983	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1298917006984	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1298917006985	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1298917006986	active site
1298917006987	catalytic site [active]
1298917006988	substrate binding site [chemical binding]; other site
1298917006989	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1298917006990	RNA/DNA hybrid binding site [nucleotide binding]; other site
1298917006991	active site
1298917006992	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1298917006993	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917006994	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1298917006995	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
1298917006996	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1298917006997	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1298917006998	catalytic residue [active]
1298917006999	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1298917007000	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1298917007001	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1298917007002	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917007003	S-adenosylmethionine binding site [chemical binding]; other site
1298917007004	hypothetical protein; Provisional; Region: PRK05421
1298917007005	putative catalytic site [active]
1298917007006	putative metal binding site [ion binding]; other site
1298917007007	putative phosphate binding site [ion binding]; other site
1298917007008	putative catalytic site [active]
1298917007009	putative phosphate binding site [ion binding]; other site
1298917007010	putative metal binding site [ion binding]; other site
1298917007011	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1298917007012	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917007013	putative substrate translocation pore; other site
1298917007014	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917007015	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917007016	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
1298917007017	putative effector binding pocket; other site
1298917007018	dimerization interface [polypeptide binding]; other site
1298917007019	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1298917007020	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1298917007021	active site
1298917007022	catalytic tetrad [active]
1298917007023	protein disaggregation chaperone; Provisional; Region: PRK10865
1298917007024	Clp amino terminal domain; Region: Clp_N; pfam02861
1298917007025	Clp amino terminal domain; Region: Clp_N; pfam02861
1298917007026	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917007027	Walker A motif; other site
1298917007028	ATP binding site [chemical binding]; other site
1298917007029	Walker B motif; other site
1298917007030	arginine finger; other site
1298917007031	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917007032	Walker A motif; other site
1298917007033	ATP binding site [chemical binding]; other site
1298917007034	Walker B motif; other site
1298917007035	arginine finger; other site
1298917007036	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1298917007037	hypothetical protein; Provisional; Region: PRK10723
1298917007038	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1298917007039	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1298917007040	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1298917007041	RNA binding surface [nucleotide binding]; other site
1298917007042	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1298917007043	active site
1298917007044	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1298917007045	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1298917007046	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1298917007047	30S subunit binding site; other site
1298917007048	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1298917007049	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1298917007050	Prephenate dehydratase; Region: PDT; pfam00800
1298917007051	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1298917007052	putative L-Phe binding site [chemical binding]; other site
1298917007053	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1298917007054	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1298917007055	Chorismate mutase type II; Region: CM_2; cl00693
1298917007056	prephenate dehydrogenase; Validated; Region: PRK08507
1298917007057	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1298917007058	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1298917007059	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1298917007060	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1298917007061	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1298917007062	metal binding site [ion binding]; metal-binding site
1298917007063	active site
1298917007064	I-site; other site
1298917007065	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1298917007066	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1298917007067	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1298917007068	RimM N-terminal domain; Region: RimM; pfam01782
1298917007069	PRC-barrel domain; Region: PRC; pfam05239
1298917007070	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1298917007071	signal recognition particle protein; Provisional; Region: PRK10867
1298917007072	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1298917007073	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1298917007074	P loop; other site
1298917007075	GTP binding site [chemical binding]; other site
1298917007076	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1298917007077	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1298917007078	hypothetical protein; Provisional; Region: PRK11573
1298917007079	Domain of unknown function DUF21; Region: DUF21; pfam01595
1298917007080	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1298917007081	Transporter associated domain; Region: CorC_HlyC; smart01091
1298917007082	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1298917007083	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1298917007084	dimer interface [polypeptide binding]; other site
1298917007085	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1298917007086	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1298917007087	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1298917007088	recombination and repair protein; Provisional; Region: PRK10869
1298917007089	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1298917007090	Walker A/P-loop; other site
1298917007091	ATP binding site [chemical binding]; other site
1298917007092	Q-loop/lid; other site
1298917007093	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1298917007094	ABC transporter signature motif; other site
1298917007095	Walker B; other site
1298917007096	D-loop; other site
1298917007097	H-loop/switch region; other site
1298917007098	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1298917007099	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1298917007100	hypothetical protein; Validated; Region: PRK01777
1298917007101	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1298917007102	putative coenzyme Q binding site [chemical binding]; other site
1298917007103	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1298917007104	SmpB-tmRNA interface; other site
1298917007105	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
1298917007106	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1298917007107	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1298917007108	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917007109	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cl00038
1298917007110	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1298917007111	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1298917007112	tail protein; Provisional; Region: D; PHA02561
1298917007113	Phage protein U [General function prediction only]; Region: COG3499
1298917007114	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1298917007115	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1298917007116	major tail tube protein; Provisional; Region: FII; PHA02600
1298917007117	major tail sheath protein; Provisional; Region: FI; PHA02560
1298917007118	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1298917007119	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1298917007120	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1298917007121	baseplate assembly protein; Provisional; Region: J; PHA02568
1298917007122	baseplate wedge subunit; Provisional; Region: W; PHA02516
1298917007123	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1298917007124	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1298917007125	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1298917007126	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1298917007127	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1298917007128	catalytic residues [active]
1298917007129	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
1298917007130	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1298917007131	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1298917007132	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1298917007133	capsid protein; Provisional; Region: N; PHA02538
1298917007134	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
1298917007135	portal vertex protein; Provisional; Region: Q; PHA02536
1298917007136	Phage portal protein; Region: Phage_portal; pfam04860
1298917007137	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
1298917007138	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1298917007139	DinI-like family; Region: DinI; pfam06183
1298917007140	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1298917007141	DNA adenine methylase (dam); Region: dam; TIGR00571
1298917007142	DksA-like zinc finger domain containing protein; Region: PHA00080
1298917007143	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1298917007144	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
1298917007145	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
1298917007146	Predicted transcriptional regulator [Transcription]; Region: COG2932
1298917007147	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
1298917007148	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1298917007149	Catalytic site [active]
1298917007150	integrase; Provisional; Region: int; PHA02601
1298917007151	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1298917007152	dimer interface [polypeptide binding]; other site
1298917007153	active site
1298917007154	catalytic residues [active]
1298917007155	Int/Topo IB signature motif; other site
1298917007156	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1298917007157	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1298917007158	Integrase core domain; Region: rve; pfam00665
1298917007159	Integrase core domain; Region: rve_3; pfam13683
1298917007160	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1298917007161	DNA-binding interface [nucleotide binding]; DNA binding site
1298917007162	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1298917007163	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
1298917007164	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1298917007165	homodimer interface [polypeptide binding]; other site
1298917007166	active site
1298917007167	TDP-binding site; other site
1298917007168	acceptor substrate-binding pocket; other site
1298917007169	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1298917007170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917007171	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1298917007172	Walker A/P-loop; other site
1298917007173	ATP binding site [chemical binding]; other site
1298917007174	Q-loop/lid; other site
1298917007175	ABC transporter signature motif; other site
1298917007176	Walker B; other site
1298917007177	D-loop; other site
1298917007178	H-loop/switch region; other site
1298917007179	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1298917007180	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1298917007181	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917007182	Walker A/P-loop; other site
1298917007183	ATP binding site [chemical binding]; other site
1298917007184	Q-loop/lid; other site
1298917007185	ABC transporter signature motif; other site
1298917007186	Walker B; other site
1298917007187	D-loop; other site
1298917007188	H-loop/switch region; other site
1298917007189	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1298917007190	outer membrane receptor FepA; Provisional; Region: PRK13528
1298917007191	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1298917007192	N-terminal plug; other site
1298917007193	ligand-binding site [chemical binding]; other site
1298917007194	secreted effector protein PipB2; Provisional; Region: PRK15196
1298917007195	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1298917007196	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1298917007197	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1298917007198	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1298917007199	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1298917007200	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
1298917007201	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
1298917007202	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1298917007203	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1298917007204	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
1298917007205	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1298917007206	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1298917007207	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917007208	dimer interface [polypeptide binding]; other site
1298917007209	phosphorylation site [posttranslational modification]
1298917007210	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917007211	ATP binding site [chemical binding]; other site
1298917007212	Mg2+ binding site [ion binding]; other site
1298917007213	G-X-G motif; other site
1298917007214	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
1298917007215	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917007216	active site
1298917007217	phosphorylation site [posttranslational modification]
1298917007218	intermolecular recognition site; other site
1298917007219	dimerization interface [polypeptide binding]; other site
1298917007220	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917007221	DNA binding site [nucleotide binding]
1298917007222	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1298917007223	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
1298917007224	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
1298917007225	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
1298917007226	substrate binding pocket [chemical binding]; other site
1298917007227	active site
1298917007228	iron coordination sites [ion binding]; other site
1298917007229	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
1298917007230	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
1298917007231	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917007232	DNA-binding site [nucleotide binding]; DNA binding site
1298917007233	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1298917007234	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1298917007235	bacterial OsmY and nodulation domain; Region: BON; smart00749
1298917007236	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1298917007237	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1298917007238	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1298917007239	dimerization interface [polypeptide binding]; other site
1298917007240	putative DNA binding site [nucleotide binding]; other site
1298917007241	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1298917007242	putative Zn2+ binding site [ion binding]; other site
1298917007243	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1298917007244	active site residue [active]
1298917007245	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1298917007246	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1298917007247	hypothetical protein; Provisional; Region: PRK10556
1298917007248	hypothetical protein; Provisional; Region: PRK10132
1298917007249	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1298917007250	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1298917007251	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1298917007252	catalytic residues [active]
1298917007253	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1298917007254	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1298917007255	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1298917007256	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1298917007257	active site
1298917007258	dimer interface [polypeptide binding]; other site
1298917007259	catalytic residues [active]
1298917007260	effector binding site; other site
1298917007261	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1298917007262	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1298917007263	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1298917007264	dimer interface [polypeptide binding]; other site
1298917007265	putative radical transfer pathway; other site
1298917007266	diiron center [ion binding]; other site
1298917007267	tyrosyl radical; other site
1298917007268	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1298917007269	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1298917007270	Walker A/P-loop; other site
1298917007271	ATP binding site [chemical binding]; other site
1298917007272	Q-loop/lid; other site
1298917007273	ABC transporter signature motif; other site
1298917007274	Walker B; other site
1298917007275	D-loop; other site
1298917007276	H-loop/switch region; other site
1298917007277	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1298917007278	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1298917007279	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1298917007280	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1298917007281	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917007282	transcriptional repressor MprA; Provisional; Region: PRK10870
1298917007283	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1298917007284	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1298917007285	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1298917007286	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917007287	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1298917007288	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1298917007289	glutamate--cysteine ligase; Provisional; Region: PRK02107
1298917007290	Predicted membrane protein [Function unknown]; Region: COG1238
1298917007291	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1298917007292	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917007293	motif II; other site
1298917007294	carbon storage regulator; Provisional; Region: PRK01712
1298917007295	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1298917007296	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1298917007297	motif 1; other site
1298917007298	active site
1298917007299	motif 2; other site
1298917007300	motif 3; other site
1298917007301	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1298917007302	DHHA1 domain; Region: DHHA1; pfam02272
1298917007303	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1298917007304	recombinase A; Provisional; Region: recA; PRK09354
1298917007305	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1298917007306	hexamer interface [polypeptide binding]; other site
1298917007307	Walker A motif; other site
1298917007308	ATP binding site [chemical binding]; other site
1298917007309	Walker B motif; other site
1298917007310	hypothetical protein; Validated; Region: PRK03661
1298917007311	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1298917007312	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1298917007313	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1298917007314	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
1298917007315	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1298917007316	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1298917007317	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1298917007318	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1298917007319	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1298917007320	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1298917007321	putative NAD(P) binding site [chemical binding]; other site
1298917007322	active site
1298917007323	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1298917007324	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1298917007325	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1298917007326	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917007327	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1298917007328	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1298917007329	putative active site [active]
1298917007330	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1298917007331	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1298917007332	GAF domain; Region: GAF; pfam01590
1298917007333	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917007334	Walker A motif; other site
1298917007335	ATP binding site [chemical binding]; other site
1298917007336	Walker B motif; other site
1298917007337	arginine finger; other site
1298917007338	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1298917007339	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1298917007340	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1298917007341	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1298917007342	iron binding site [ion binding]; other site
1298917007343	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1298917007344	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917007345	Acylphosphatase; Region: Acylphosphatase; pfam00708
1298917007346	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1298917007347	HypF finger; Region: zf-HYPF; pfam07503
1298917007348	HypF finger; Region: zf-HYPF; pfam07503
1298917007349	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1298917007350	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1298917007351	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1298917007352	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1298917007353	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1298917007354	nickel binding site [ion binding]; other site
1298917007355	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1298917007356	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1298917007357	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1298917007358	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1298917007359	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1298917007360	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1298917007361	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1298917007362	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1298917007363	NADH dehydrogenase; Region: NADHdh; cl00469
1298917007364	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1298917007365	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
1298917007366	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1298917007367	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1298917007368	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1298917007369	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1298917007370	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1298917007371	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1298917007372	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1298917007373	dimerization interface [polypeptide binding]; other site
1298917007374	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1298917007375	ATP binding site [chemical binding]; other site
1298917007376	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1298917007377	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1298917007378	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1298917007379	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917007380	Walker A motif; other site
1298917007381	ATP binding site [chemical binding]; other site
1298917007382	Walker B motif; other site
1298917007383	arginine finger; other site
1298917007384	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1298917007385	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1298917007386	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1298917007387	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1298917007388	metal binding site [ion binding]; metal-binding site
1298917007389	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1298917007390	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1298917007391	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1298917007392	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1298917007393	ABC-ATPase subunit  interface; other site
1298917007394	dimer interface [polypeptide binding]; other site
1298917007395	putative PBP binding regions; other site
1298917007396	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1298917007397	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1298917007398	ABC-ATPase subunit  interface; other site
1298917007399	dimer interface [polypeptide binding]; other site
1298917007400	putative PBP binding regions; other site
1298917007401	transcriptional activator SprB; Provisional; Region: PRK15320
1298917007402	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1298917007403	transcriptional regulator SirC; Provisional; Region: PRK15044
1298917007404	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917007405	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
1298917007406	invasion protein OrgB; Provisional; Region: PRK15322
1298917007407	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
1298917007408	invasion protein OrgA; Provisional; Region: PRK15323
1298917007409	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
1298917007410	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
1298917007411	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
1298917007412	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
1298917007413	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
1298917007414	transcriptional regulator HilD; Provisional; Region: PRK15185
1298917007415	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917007416	invasion protein regulator; Provisional; Region: PRK12370
1298917007417	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917007418	DNA binding site [nucleotide binding]
1298917007419	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1298917007420	binding surface
1298917007421	TPR motif; other site
1298917007422	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1298917007423	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1298917007424	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1298917007425	catalytic residue [active]
1298917007426	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
1298917007427	SicP binding; Region: SicP-binding; pfam09119
1298917007428	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
1298917007429	switch II binding region; other site
1298917007430	Rac1 P-loop interaction site [polypeptide binding]; other site
1298917007431	GTP binding residues [chemical binding]; other site
1298917007432	switch I binding region; other site
1298917007433	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
1298917007434	active site
1298917007435	chaperone protein SicP; Provisional; Region: PRK15329
1298917007436	putative acyl carrier protein IacP; Validated; Region: PRK08172
1298917007437	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
1298917007438	cell invasion protein SipD; Provisional; Region: PRK15330
1298917007439	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
1298917007440	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
1298917007441	chaperone protein SicA; Provisional; Region: PRK15331
1298917007442	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1298917007443	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1298917007444	type III secretion system protein SpaS; Validated; Region: PRK08156
1298917007445	type III secretion system protein SpaR; Provisional; Region: PRK15332
1298917007446	type III secretion system protein SpaQ; Provisional; Region: PRK15333
1298917007447	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
1298917007448	type III secretion system protein SpaO; Validated; Region: PRK08158
1298917007449	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1298917007450	antigen presentation protein SpaN; Provisional; Region: PRK15334
1298917007451	Surface presentation of antigens protein; Region: SPAN; pfam02510
1298917007452	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
1298917007453	ATP synthase SpaL; Validated; Region: PRK08149
1298917007454	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1298917007455	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1298917007456	Walker A motif; other site
1298917007457	ATP binding site [chemical binding]; other site
1298917007458	Walker B motif; other site
1298917007459	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
1298917007460	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
1298917007461	type III secretion system protein InvA; Provisional; Region: PRK15337
1298917007462	type III secretion system regulator InvE; Provisional; Region: PRK15338
1298917007463	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
1298917007464	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
1298917007465	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1298917007466	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1298917007467	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1298917007468	transcriptional regulator InvF; Provisional; Region: PRK15340
1298917007469	InvH outer membrane lipoprotein; Region: InvH; pfam04741
1298917007470	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1298917007471	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1298917007472	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1298917007473	active site
1298917007474	metal binding site [ion binding]; metal-binding site
1298917007475	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1298917007476	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1298917007477	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1298917007478	putative aldolase; Validated; Region: PRK08130
1298917007479	intersubunit interface [polypeptide binding]; other site
1298917007480	active site
1298917007481	Zn2+ binding site [ion binding]; other site
1298917007482	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1298917007483	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1298917007484	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1298917007485	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1298917007486	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1298917007487	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917007488	MarR family; Region: MarR_2; cl17246
1298917007489	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1298917007490	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1298917007491	Flavoprotein; Region: Flavoprotein; pfam02441
1298917007492	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1298917007493	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1298917007494	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1298917007495	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1298917007496	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1298917007497	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1298917007498	DNA binding residues [nucleotide binding]
1298917007499	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
1298917007500	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1298917007501	Peptidase family M23; Region: Peptidase_M23; pfam01551
1298917007502	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1298917007503	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917007504	S-adenosylmethionine binding site [chemical binding]; other site
1298917007505	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1298917007506	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1298917007507	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1298917007508	Permutation of conserved domain; other site
1298917007509	active site
1298917007510	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1298917007511	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1298917007512	homotrimer interaction site [polypeptide binding]; other site
1298917007513	zinc binding site [ion binding]; other site
1298917007514	CDP-binding sites; other site
1298917007515	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1298917007516	substrate binding site; other site
1298917007517	dimer interface; other site
1298917007518	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1298917007519	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1298917007520	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
1298917007521	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1298917007522	ligand-binding site [chemical binding]; other site
1298917007523	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1298917007524	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1298917007525	CysD dimerization site [polypeptide binding]; other site
1298917007526	G1 box; other site
1298917007527	putative GEF interaction site [polypeptide binding]; other site
1298917007528	GTP/Mg2+ binding site [chemical binding]; other site
1298917007529	Switch I region; other site
1298917007530	G2 box; other site
1298917007531	G3 box; other site
1298917007532	Switch II region; other site
1298917007533	G4 box; other site
1298917007534	G5 box; other site
1298917007535	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1298917007536	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1298917007537	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1298917007538	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1298917007539	metal binding site [ion binding]; metal-binding site
1298917007540	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
1298917007541	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
1298917007542	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
1298917007543	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
1298917007544	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
1298917007545	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09731
1298917007546	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
1298917007547	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1298917007548	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
1298917007549	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1298917007550	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
1298917007551	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1298917007552	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1298917007553	Active Sites [active]
1298917007554	sulfite reductase subunit beta; Provisional; Region: PRK13504
1298917007555	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1298917007556	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1298917007557	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1298917007558	Flavodoxin; Region: Flavodoxin_1; pfam00258
1298917007559	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1298917007560	FAD binding pocket [chemical binding]; other site
1298917007561	FAD binding motif [chemical binding]; other site
1298917007562	catalytic residues [active]
1298917007563	NAD binding pocket [chemical binding]; other site
1298917007564	phosphate binding motif [ion binding]; other site
1298917007565	beta-alpha-beta structure motif; other site
1298917007566	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1298917007567	active site
1298917007568	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
1298917007569	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1298917007570	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1298917007571	enolase; Provisional; Region: eno; PRK00077
1298917007572	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1298917007573	dimer interface [polypeptide binding]; other site
1298917007574	metal binding site [ion binding]; metal-binding site
1298917007575	substrate binding pocket [chemical binding]; other site
1298917007576	CTP synthetase; Validated; Region: pyrG; PRK05380
1298917007577	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1298917007578	Catalytic site [active]
1298917007579	active site
1298917007580	UTP binding site [chemical binding]; other site
1298917007581	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1298917007582	active site
1298917007583	putative oxyanion hole; other site
1298917007584	catalytic triad [active]
1298917007585	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1298917007586	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1298917007587	homodimer interface [polypeptide binding]; other site
1298917007588	metal binding site [ion binding]; metal-binding site
1298917007589	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1298917007590	homodimer interface [polypeptide binding]; other site
1298917007591	active site
1298917007592	putative chemical substrate binding site [chemical binding]; other site
1298917007593	metal binding site [ion binding]; metal-binding site
1298917007594	fimbrial protein SteA; Provisional; Region: PRK15261
1298917007595	putative periplasmic fimbrial chaperone protein SteC; Provisional; Region: PRK15274
1298917007596	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917007597	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917007598	putative fimbrial protein SteD; Provisional; Region: PRK15275
1298917007599	putative fimbrial subunit SteE; Provisional; Region: PRK15276
1298917007600	fimbrial protein SteF; Provisional; Region: PRK15260
1298917007601	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1298917007602	HD domain; Region: HD_4; pfam13328
1298917007603	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1298917007604	synthetase active site [active]
1298917007605	NTP binding site [chemical binding]; other site
1298917007606	metal binding site [ion binding]; metal-binding site
1298917007607	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1298917007608	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1298917007609	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1298917007610	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1298917007611	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917007612	dimerization interface [polypeptide binding]; other site
1298917007613	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917007614	dimer interface [polypeptide binding]; other site
1298917007615	phosphorylation site [posttranslational modification]
1298917007616	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917007617	ATP binding site [chemical binding]; other site
1298917007618	Mg2+ binding site [ion binding]; other site
1298917007619	G-X-G motif; other site
1298917007620	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1298917007621	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917007622	active site
1298917007623	phosphorylation site [posttranslational modification]
1298917007624	intermolecular recognition site; other site
1298917007625	dimerization interface [polypeptide binding]; other site
1298917007626	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1298917007627	putative binding surface; other site
1298917007628	active site
1298917007629	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1298917007630	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1298917007631	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1298917007632	active site
1298917007633	tetramer interface [polypeptide binding]; other site
1298917007634	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917007635	D-galactonate transporter; Region: 2A0114; TIGR00893
1298917007636	putative substrate translocation pore; other site
1298917007637	flavodoxin; Provisional; Region: PRK08105
1298917007638	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1298917007639	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1298917007640	probable active site [active]
1298917007641	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
1298917007642	SecY interacting protein Syd; Provisional; Region: PRK04968
1298917007643	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1298917007644	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1298917007645	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1298917007646	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1298917007647	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1298917007648	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1298917007649	serine transporter; Region: stp; TIGR00814
1298917007650	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1298917007651	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1298917007652	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1298917007653	flap endonuclease-like protein; Provisional; Region: PRK09482
1298917007654	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1298917007655	active site
1298917007656	metal binding site 1 [ion binding]; metal-binding site
1298917007657	putative 5' ssDNA interaction site; other site
1298917007658	metal binding site 3; metal-binding site
1298917007659	metal binding site 2 [ion binding]; metal-binding site
1298917007660	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1298917007661	putative DNA binding site [nucleotide binding]; other site
1298917007662	putative metal binding site [ion binding]; other site
1298917007663	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1298917007664	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1298917007665	dimer interface [polypeptide binding]; other site
1298917007666	active site
1298917007667	metal binding site [ion binding]; metal-binding site
1298917007668	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1298917007669	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1298917007670	intersubunit interface [polypeptide binding]; other site
1298917007671	active site
1298917007672	Zn2+ binding site [ion binding]; other site
1298917007673	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1298917007674	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917007675	putative substrate translocation pore; other site
1298917007676	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1298917007677	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
1298917007678	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1298917007679	trimer interface [polypeptide binding]; other site
1298917007680	substrate binding site [chemical binding]; other site
1298917007681	Mn binding site [ion binding]; other site
1298917007682	L-fuculokinase; Provisional; Region: PRK10331
1298917007683	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1298917007684	nucleotide binding site [chemical binding]; other site
1298917007685	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
1298917007686	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1298917007687	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1298917007688	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917007689	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1298917007690	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1298917007691	hypothetical protein; Provisional; Region: PRK10873
1298917007692	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1298917007693	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917007694	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1298917007695	dimerization interface [polypeptide binding]; other site
1298917007696	substrate binding pocket [chemical binding]; other site
1298917007697	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1298917007698	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1298917007699	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1298917007700	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1298917007701	catalytic residue [active]
1298917007702	CsdA-binding activator; Provisional; Region: PRK15019
1298917007703	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1298917007704	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1298917007705	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1298917007706	putative ATP binding site [chemical binding]; other site
1298917007707	putative substrate interface [chemical binding]; other site
1298917007708	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1298917007709	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1298917007710	MltA specific insert domain; Region: MltA; pfam03562
1298917007711	3D domain; Region: 3D; pfam06725
1298917007712	AMIN domain; Region: AMIN; pfam11741
1298917007713	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1298917007714	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1298917007715	active site
1298917007716	metal binding site [ion binding]; metal-binding site
1298917007717	N-acetylglutamate synthase; Validated; Region: PRK05279
1298917007718	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1298917007719	putative feedback inhibition sensing region; other site
1298917007720	putative nucleotide binding site [chemical binding]; other site
1298917007721	putative substrate binding site [chemical binding]; other site
1298917007722	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917007723	Coenzyme A binding pocket [chemical binding]; other site
1298917007724	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1298917007725	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1298917007726	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1298917007727	hypothetical protein; Provisional; Region: PRK10332
1298917007728	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1298917007729	hypothetical protein; Provisional; Region: PRK11521
1298917007730	hypothetical protein; Provisional; Region: PRK10557
1298917007731	hypothetical protein; Provisional; Region: PRK10506
1298917007732	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1298917007733	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1298917007734	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1298917007735	dimerization interface [polypeptide binding]; other site
1298917007736	active site
1298917007737	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1298917007738	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1298917007739	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1298917007740	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1298917007741	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1298917007742	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1298917007743	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1298917007744	putative active site [active]
1298917007745	Ap4A binding site [chemical binding]; other site
1298917007746	nudix motif; other site
1298917007747	putative metal binding site [ion binding]; other site
1298917007748	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1298917007749	putative DNA-binding cleft [nucleotide binding]; other site
1298917007750	putative DNA clevage site; other site
1298917007751	molecular lever; other site
1298917007752	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1298917007753	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1298917007754	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1298917007755	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1298917007756	active site
1298917007757	catalytic tetrad [active]
1298917007758	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1298917007759	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917007760	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1298917007761	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1298917007762	putative acyl-acceptor binding pocket; other site
1298917007763	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1298917007764	acyl-activating enzyme (AAE) consensus motif; other site
1298917007765	putative AMP binding site [chemical binding]; other site
1298917007766	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1298917007767	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917007768	DNA binding site [nucleotide binding]
1298917007769	domain linker motif; other site
1298917007770	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1298917007771	dimerization interface (closed form) [polypeptide binding]; other site
1298917007772	ligand binding site [chemical binding]; other site
1298917007773	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1298917007774	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1298917007775	active site
1298917007776	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1298917007777	substrate binding site [chemical binding]; other site
1298917007778	catalytic residues [active]
1298917007779	dimer interface [polypeptide binding]; other site
1298917007780	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1298917007781	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917007782	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1298917007783	dimerization interface [polypeptide binding]; other site
1298917007784	putative racemase; Provisional; Region: PRK10200
1298917007785	aspartate racemase; Region: asp_race; TIGR00035
1298917007786	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1298917007787	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917007788	putative substrate translocation pore; other site
1298917007789	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917007790	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1298917007791	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1298917007792	NADP binding site [chemical binding]; other site
1298917007793	homodimer interface [polypeptide binding]; other site
1298917007794	active site
1298917007795	putative acyltransferase; Provisional; Region: PRK05790
1298917007796	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1298917007797	dimer interface [polypeptide binding]; other site
1298917007798	active site
1298917007799	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917007800	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917007801	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1298917007802	dimerization interface [polypeptide binding]; other site
1298917007803	Predicted membrane protein [Function unknown]; Region: COG4125
1298917007804	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1298917007805	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1298917007806	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1298917007807	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1298917007808	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1298917007809	putative metal binding site [ion binding]; other site
1298917007810	putative homodimer interface [polypeptide binding]; other site
1298917007811	putative homotetramer interface [polypeptide binding]; other site
1298917007812	putative homodimer-homodimer interface [polypeptide binding]; other site
1298917007813	putative allosteric switch controlling residues; other site
1298917007814	High-affinity nickel-transport protein; Region: NicO; cl00964
1298917007815	transcriptional activator SprB; Provisional; Region: PRK15320
1298917007816	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14600
1298917007817	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
1298917007818	Fimbrial protein; Region: Fimbrial; pfam00419
1298917007819	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
1298917007820	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917007821	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917007822	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
1298917007823	PapC N-terminal domain; Region: PapC_N; pfam13954
1298917007824	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1298917007825	PapC C-terminal domain; Region: PapC_C; pfam13953
1298917007826	fimbrial protein StdA; Provisional; Region: PRK15210
1298917007827	hypothetical protein; Provisional; Region: PRK10316
1298917007828	YfdX protein; Region: YfdX; pfam10938
1298917007829	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1298917007830	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1298917007831	oligomeric interface; other site
1298917007832	putative active site [active]
1298917007833	homodimer interface [polypeptide binding]; other site
1298917007834	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1298917007835	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1298917007836	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
1298917007837	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1298917007838	Peptidase family M23; Region: Peptidase_M23; pfam01551
1298917007839	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1298917007840	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1298917007841	active site
1298917007842	metal binding site [ion binding]; metal-binding site
1298917007843	nudix motif; other site
1298917007844	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1298917007845	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1298917007846	dimer interface [polypeptide binding]; other site
1298917007847	putative anticodon binding site; other site
1298917007848	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1298917007849	motif 1; other site
1298917007850	active site
1298917007851	motif 2; other site
1298917007852	motif 3; other site
1298917007853	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1298917007854	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1298917007855	RF-1 domain; Region: RF-1; pfam00472
1298917007856	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1298917007857	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1298917007858	dimerization domain [polypeptide binding]; other site
1298917007859	dimer interface [polypeptide binding]; other site
1298917007860	catalytic residues [active]
1298917007861	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1298917007862	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1298917007863	active site
1298917007864	Int/Topo IB signature motif; other site
1298917007865	flavodoxin FldB; Provisional; Region: PRK12359
1298917007866	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1298917007867	hypothetical protein; Provisional; Region: PRK10878
1298917007868	putative global regulator; Reviewed; Region: PRK09559
1298917007869	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1298917007870	hemolysin; Provisional; Region: PRK15087
1298917007871	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1298917007872	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1298917007873	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1298917007874	beta-galactosidase; Region: BGL; TIGR03356
1298917007875	glycine dehydrogenase; Provisional; Region: PRK05367
1298917007876	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1298917007877	tetramer interface [polypeptide binding]; other site
1298917007878	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917007879	catalytic residue [active]
1298917007880	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1298917007881	tetramer interface [polypeptide binding]; other site
1298917007882	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917007883	catalytic residue [active]
1298917007884	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1298917007885	lipoyl attachment site [posttranslational modification]; other site
1298917007886	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1298917007887	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1298917007888	oxidoreductase; Provisional; Region: PRK08013
1298917007889	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1298917007890	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1298917007891	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1298917007892	proline aminopeptidase P II; Provisional; Region: PRK10879
1298917007893	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1298917007894	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1298917007895	active site
1298917007896	hypothetical protein; Reviewed; Region: PRK01736
1298917007897	Z-ring-associated protein; Provisional; Region: PRK10972
1298917007898	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1298917007899	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1298917007900	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1298917007901	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1298917007902	ligand binding site [chemical binding]; other site
1298917007903	NAD binding site [chemical binding]; other site
1298917007904	tetramer interface [polypeptide binding]; other site
1298917007905	catalytic site [active]
1298917007906	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1298917007907	L-serine binding site [chemical binding]; other site
1298917007908	ACT domain interface; other site
1298917007909	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1298917007910	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1298917007911	active site
1298917007912	dimer interface [polypeptide binding]; other site
1298917007913	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1298917007914	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917007915	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1298917007916	putative dimerization interface [polypeptide binding]; other site
1298917007917	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1298917007918	oxidative stress defense protein; Provisional; Region: PRK11087
1298917007919	arginine exporter protein; Provisional; Region: PRK09304
1298917007920	mechanosensitive channel MscS; Provisional; Region: PRK10334
1298917007921	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1298917007922	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1298917007923	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1298917007924	active site
1298917007925	intersubunit interface [polypeptide binding]; other site
1298917007926	zinc binding site [ion binding]; other site
1298917007927	Na+ binding site [ion binding]; other site
1298917007928	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1298917007929	Phosphoglycerate kinase; Region: PGK; pfam00162
1298917007930	substrate binding site [chemical binding]; other site
1298917007931	hinge regions; other site
1298917007932	ADP binding site [chemical binding]; other site
1298917007933	catalytic site [active]
1298917007934	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1298917007935	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1298917007936	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1298917007937	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1298917007938	trimer interface [polypeptide binding]; other site
1298917007939	putative Zn binding site [ion binding]; other site
1298917007940	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1298917007941	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1298917007942	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1298917007943	Walker A/P-loop; other site
1298917007944	ATP binding site [chemical binding]; other site
1298917007945	Q-loop/lid; other site
1298917007946	ABC transporter signature motif; other site
1298917007947	Walker B; other site
1298917007948	D-loop; other site
1298917007949	H-loop/switch region; other site
1298917007950	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1298917007951	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1298917007952	Walker A/P-loop; other site
1298917007953	ATP binding site [chemical binding]; other site
1298917007954	Q-loop/lid; other site
1298917007955	ABC transporter signature motif; other site
1298917007956	Walker B; other site
1298917007957	D-loop; other site
1298917007958	H-loop/switch region; other site
1298917007959	transketolase; Reviewed; Region: PRK12753
1298917007960	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1298917007961	TPP-binding site [chemical binding]; other site
1298917007962	dimer interface [polypeptide binding]; other site
1298917007963	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1298917007964	PYR/PP interface [polypeptide binding]; other site
1298917007965	dimer interface [polypeptide binding]; other site
1298917007966	TPP binding site [chemical binding]; other site
1298917007967	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1298917007968	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1298917007969	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1298917007970	agmatinase; Region: agmatinase; TIGR01230
1298917007971	oligomer interface [polypeptide binding]; other site
1298917007972	putative active site [active]
1298917007973	Mn binding site [ion binding]; other site
1298917007974	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1298917007975	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1298917007976	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
1298917007977	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1298917007978	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1298917007979	putative NAD(P) binding site [chemical binding]; other site
1298917007980	catalytic Zn binding site [ion binding]; other site
1298917007981	structural Zn binding site [ion binding]; other site
1298917007982	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1298917007983	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1298917007984	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1298917007985	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1298917007986	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1298917007987	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917007988	DNA-binding site [nucleotide binding]; DNA binding site
1298917007989	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1298917007990	DNA phosphorothioation-dependent restriction protein DptH; Region: dnd_assoc_2; TIGR03237
1298917007991	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1298917007992	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1298917007993	dimer interface [polypeptide binding]; other site
1298917007994	active site
1298917007995	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1298917007996	catalytic residues [active]
1298917007997	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1298917007998	Virulence promoting factor; Region: YqgB; pfam11036
1298917007999	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1298917008000	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1298917008001	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1298917008002	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1298917008003	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1298917008004	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917008005	putative substrate translocation pore; other site
1298917008006	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917008007	hypothetical protein; Provisional; Region: PRK04860
1298917008008	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1298917008009	DNA-specific endonuclease I; Provisional; Region: PRK15137
1298917008010	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1298917008011	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1298917008012	RNA methyltransferase, RsmE family; Region: TIGR00046
1298917008013	glutathione synthetase; Provisional; Region: PRK05246
1298917008014	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1298917008015	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1298917008016	hypothetical protein; Validated; Region: PRK00228
1298917008017	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1298917008018	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1298917008019	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1298917008020	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1298917008021	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1298917008022	Walker A motif; other site
1298917008023	ATP binding site [chemical binding]; other site
1298917008024	Walker B motif; other site
1298917008025	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1298917008026	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1298917008027	catalytic residue [active]
1298917008028	YGGT family; Region: YGGT; pfam02325
1298917008029	YGGT family; Region: YGGT; pfam02325
1298917008030	hypothetical protein; Validated; Region: PRK05090
1298917008031	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1298917008032	active site
1298917008033	dimerization interface [polypeptide binding]; other site
1298917008034	HemN family oxidoreductase; Provisional; Region: PRK05660
1298917008035	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917008036	FeS/SAM binding site; other site
1298917008037	HemN C-terminal domain; Region: HemN_C; pfam06969
1298917008038	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
1298917008039	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
1298917008040	homodimer interface [polypeptide binding]; other site
1298917008041	active site
1298917008042	hypothetical protein; Provisional; Region: PRK10626
1298917008043	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1298917008044	hypothetical protein; Provisional; Region: PRK11702
1298917008045	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1298917008046	adenine DNA glycosylase; Provisional; Region: PRK10880
1298917008047	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1298917008048	minor groove reading motif; other site
1298917008049	helix-hairpin-helix signature motif; other site
1298917008050	substrate binding pocket [chemical binding]; other site
1298917008051	active site
1298917008052	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1298917008053	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1298917008054	DNA binding and oxoG recognition site [nucleotide binding]
1298917008055	oxidative damage protection protein; Provisional; Region: PRK05408
1298917008056	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1298917008057	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1298917008058	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1298917008059	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1298917008060	catalytic residue [active]
1298917008061	nucleoside transporter; Region: 2A0110; TIGR00889
1298917008062	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
1298917008063	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
1298917008064	dimer interface [polypeptide binding]; other site
1298917008065	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1298917008066	metal binding site [ion binding]; metal-binding site
1298917008067	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
1298917008068	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1298917008069	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1298917008070	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
1298917008071	putative active site [active]
1298917008072	putative catalytic site [active]
1298917008073	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1298917008074	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1298917008075	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917008076	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
1298917008077	putative dimerization interface [polypeptide binding]; other site
1298917008078	putative substrate binding pocket [chemical binding]; other site
1298917008079	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1298917008080	Sulfatase; Region: Sulfatase; pfam00884
1298917008081	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1298917008082	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917008083	FeS/SAM binding site; other site
1298917008084	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1298917008085	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1298917008086	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917008087	DNA binding residues [nucleotide binding]
1298917008088	dimerization interface [polypeptide binding]; other site
1298917008089	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
1298917008090	Amino acid permease; Region: AA_permease_2; pfam13520
1298917008091	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
1298917008092	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1298917008093	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1298917008094	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
1298917008095	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1298917008096	NAD(P) binding site [chemical binding]; other site
1298917008097	catalytic residues [active]
1298917008098	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
1298917008099	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1298917008100	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1298917008101	active site
1298917008102	catalytic site [active]
1298917008103	Zn binding site [ion binding]; other site
1298917008104	tetramer interface [polypeptide binding]; other site
1298917008105	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1298917008106	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
1298917008107	putative active site [active]
1298917008108	catalytic triad [active]
1298917008109	putative dimer interface [polypeptide binding]; other site
1298917008110	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917008111	D-galactonate transporter; Region: 2A0114; TIGR00893
1298917008112	putative substrate translocation pore; other site
1298917008113	mannonate dehydratase; Provisional; Region: PRK03906
1298917008114	mannonate dehydratase; Region: uxuA; TIGR00695
1298917008115	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1298917008116	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1298917008117	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1298917008118	Glucuronate isomerase; Region: UxaC; pfam02614
1298917008119	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1298917008120	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1298917008121	dimer interface [polypeptide binding]; other site
1298917008122	putative CheW interface [polypeptide binding]; other site
1298917008123	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1298917008124	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1298917008125	CHAP domain; Region: CHAP; pfam05257
1298917008126	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1298917008127	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1298917008128	putative ligand binding residues [chemical binding]; other site
1298917008129	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1298917008130	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
1298917008131	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1298917008132	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
1298917008133	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
1298917008134	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1298917008135	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1298917008136	putative substrate-binding site; other site
1298917008137	nickel binding site [ion binding]; other site
1298917008138	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1298917008139	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1298917008140	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
1298917008141	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1298917008142	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
1298917008143	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1298917008144	hydrogenase 2 small subunit; Provisional; Region: PRK10468
1298917008145	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1298917008146	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1298917008147	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
1298917008148	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1298917008149	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917008150	dimerization interface [polypeptide binding]; other site
1298917008151	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1298917008152	dimer interface [polypeptide binding]; other site
1298917008153	putative CheW interface [polypeptide binding]; other site
1298917008154	hypothetical protein; Provisional; Region: PRK05208
1298917008155	oxidoreductase; Provisional; Region: PRK07985
1298917008156	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1298917008157	NAD binding site [chemical binding]; other site
1298917008158	metal binding site [ion binding]; metal-binding site
1298917008159	active site
1298917008160	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1298917008161	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1298917008162	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1298917008163	cystathionine beta-lyase; Provisional; Region: PRK08114
1298917008164	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1298917008165	homodimer interface [polypeptide binding]; other site
1298917008166	substrate-cofactor binding pocket; other site
1298917008167	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917008168	catalytic residue [active]
1298917008169	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1298917008170	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1298917008171	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1298917008172	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1298917008173	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917008174	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917008175	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1298917008176	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1298917008177	dimer interface [polypeptide binding]; other site
1298917008178	active site
1298917008179	metal binding site [ion binding]; metal-binding site
1298917008180	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1298917008181	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1298917008182	active site
1298917008183	catalytic tetrad [active]
1298917008184	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1298917008185	nucleotide binding site/active site [active]
1298917008186	catalytic residue [active]
1298917008187	hypothetical protein; Provisional; Region: PRK01254
1298917008188	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1298917008189	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1298917008190	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1298917008191	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1298917008192	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1298917008193	DctM-like transporters; Region: DctM; pfam06808
1298917008194	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
1298917008195	FtsI repressor; Provisional; Region: PRK10883
1298917008196	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1298917008197	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1298917008198	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1298917008199	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1298917008200	putative acyl-acceptor binding pocket; other site
1298917008201	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1298917008202	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917008203	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1298917008204	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1298917008205	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1298917008206	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917008207	active site
1298917008208	phosphorylation site [posttranslational modification]
1298917008209	intermolecular recognition site; other site
1298917008210	dimerization interface [polypeptide binding]; other site
1298917008211	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917008212	DNA binding site [nucleotide binding]
1298917008213	sensor protein QseC; Provisional; Region: PRK10337
1298917008214	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1298917008215	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917008216	dimer interface [polypeptide binding]; other site
1298917008217	phosphorylation site [posttranslational modification]
1298917008218	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917008219	ATP binding site [chemical binding]; other site
1298917008220	Mg2+ binding site [ion binding]; other site
1298917008221	G-X-G motif; other site
1298917008222	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1298917008223	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1298917008224	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1298917008225	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917008226	ATP binding site [chemical binding]; other site
1298917008227	Mg2+ binding site [ion binding]; other site
1298917008228	G-X-G motif; other site
1298917008229	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1298917008230	anchoring element; other site
1298917008231	dimer interface [polypeptide binding]; other site
1298917008232	ATP binding site [chemical binding]; other site
1298917008233	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1298917008234	active site
1298917008235	metal binding site [ion binding]; metal-binding site
1298917008236	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1298917008237	esterase YqiA; Provisional; Region: PRK11071
1298917008238	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1298917008239	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1298917008240	active site
1298917008241	metal binding site [ion binding]; metal-binding site
1298917008242	hexamer interface [polypeptide binding]; other site
1298917008243	putative dehydrogenase; Provisional; Region: PRK11039
1298917008244	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1298917008245	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1298917008246	dimer interface [polypeptide binding]; other site
1298917008247	ADP-ribose binding site [chemical binding]; other site
1298917008248	active site
1298917008249	nudix motif; other site
1298917008250	metal binding site [ion binding]; metal-binding site
1298917008251	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1298917008252	hypothetical protein; Provisional; Region: PRK11653
1298917008253	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1298917008254	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1298917008255	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1298917008256	putative active site [active]
1298917008257	metal binding site [ion binding]; metal-binding site
1298917008258	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
1298917008259	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1298917008260	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1298917008261	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1298917008262	catalytic residues [active]
1298917008263	hinge region; other site
1298917008264	alpha helical domain; other site
1298917008265	putative disulfide oxidoreductase; Provisional; Region: PRK04307
1298917008266	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1298917008267	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1298917008268	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1298917008269	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
1298917008270	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
1298917008271	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1298917008272	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1298917008273	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1298917008274	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1298917008275	putative ribose interaction site [chemical binding]; other site
1298917008276	putative ADP binding site [chemical binding]; other site
1298917008277	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1298917008278	active site
1298917008279	nucleotide binding site [chemical binding]; other site
1298917008280	HIGH motif; other site
1298917008281	KMSKS motif; other site
1298917008282	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1298917008283	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1298917008284	metal binding triad; other site
1298917008285	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1298917008286	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1298917008287	metal binding triad; other site
1298917008288	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1298917008289	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1298917008290	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1298917008291	putative active site [active]
1298917008292	putative metal binding residues [ion binding]; other site
1298917008293	signature motif; other site
1298917008294	putative triphosphate binding site [ion binding]; other site
1298917008295	CHAD domain; Region: CHAD; pfam05235
1298917008296	SH3 domain-containing protein; Provisional; Region: PRK10884
1298917008297	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1298917008298	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1298917008299	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1298917008300	active site
1298917008301	NTP binding site [chemical binding]; other site
1298917008302	metal binding triad [ion binding]; metal-binding site
1298917008303	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1298917008304	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1298917008305	Zn2+ binding site [ion binding]; other site
1298917008306	Mg2+ binding site [ion binding]; other site
1298917008307	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1298917008308	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1298917008309	homooctamer interface [polypeptide binding]; other site
1298917008310	active site
1298917008311	UGMP family protein; Validated; Region: PRK09604
1298917008312	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1298917008313	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1298917008314	DNA primase; Validated; Region: dnaG; PRK05667
1298917008315	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1298917008316	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1298917008317	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1298917008318	active site
1298917008319	metal binding site [ion binding]; metal-binding site
1298917008320	interdomain interaction site; other site
1298917008321	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1298917008322	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1298917008323	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1298917008324	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1298917008325	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1298917008326	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1298917008327	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1298917008328	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1298917008329	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1298917008330	DNA binding residues [nucleotide binding]
1298917008331	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1298917008332	active site
1298917008333	SUMO-1 interface [polypeptide binding]; other site
1298917008334	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1298917008335	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1298917008336	FAD binding pocket [chemical binding]; other site
1298917008337	FAD binding motif [chemical binding]; other site
1298917008338	phosphate binding motif [ion binding]; other site
1298917008339	NAD binding pocket [chemical binding]; other site
1298917008340	Predicted transcriptional regulators [Transcription]; Region: COG1695
1298917008341	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1298917008342	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1298917008343	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917008344	dimerization interface [polypeptide binding]; other site
1298917008345	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1298917008346	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1298917008347	dimer interface [polypeptide binding]; other site
1298917008348	putative CheW interface [polypeptide binding]; other site
1298917008349	PAS fold; Region: PAS_3; pfam08447
1298917008350	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1298917008351	putative active site [active]
1298917008352	heme pocket [chemical binding]; other site
1298917008353	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1298917008354	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1298917008355	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1298917008356	dimer interface [polypeptide binding]; other site
1298917008357	putative CheW interface [polypeptide binding]; other site
1298917008358	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
1298917008359	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1298917008360	inhibitor-cofactor binding pocket; inhibition site
1298917008361	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917008362	catalytic residue [active]
1298917008363	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1298917008364	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1298917008365	active site
1298917008366	FMN binding site [chemical binding]; other site
1298917008367	2,4-decadienoyl-CoA binding site; other site
1298917008368	catalytic residue [active]
1298917008369	4Fe-4S cluster binding site [ion binding]; other site
1298917008370	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1298917008371	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1298917008372	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1298917008373	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917008374	S-adenosylmethionine binding site [chemical binding]; other site
1298917008375	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1298917008376	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1298917008377	putative active site [active]
1298917008378	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1298917008379	serine/threonine transporter SstT; Provisional; Region: PRK13628
1298917008380	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1298917008381	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1298917008382	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1298917008383	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1298917008384	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1298917008385	Bacterial protein of unknown function (DUF883); Region: DUF883; cl01888
1298917008386	Predicted membrane protein [Function unknown]; Region: COG5393
1298917008387	YqjK-like protein; Region: YqjK; pfam13997
1298917008388	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1298917008389	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1298917008390	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1298917008391	putative dimer interface [polypeptide binding]; other site
1298917008392	N-terminal domain interface [polypeptide binding]; other site
1298917008393	putative substrate binding pocket (H-site) [chemical binding]; other site
1298917008394	Predicted membrane protein [Function unknown]; Region: COG3152
1298917008395	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917008396	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1298917008397	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1298917008398	dimerization interface [polypeptide binding]; other site
1298917008399	Pirin-related protein [General function prediction only]; Region: COG1741
1298917008400	Pirin; Region: Pirin; pfam02678
1298917008401	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1298917008402	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1298917008403	Pyruvate formate lyase 1; Region: PFL1; cd01678
1298917008404	coenzyme A binding site [chemical binding]; other site
1298917008405	active site
1298917008406	catalytic residues [active]
1298917008407	glycine loop; other site
1298917008408	propionate/acetate kinase; Provisional; Region: PRK12379
1298917008409	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
1298917008410	threonine/serine transporter TdcC; Provisional; Region: PRK13629
1298917008411	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1298917008412	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1298917008413	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1298917008414	tetramer interface [polypeptide binding]; other site
1298917008415	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917008416	catalytic residue [active]
1298917008417	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1298917008418	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917008419	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1298917008420	putative substrate binding pocket [chemical binding]; other site
1298917008421	putative dimerization interface [polypeptide binding]; other site
1298917008422	glycerate kinase I; Provisional; Region: PRK10342
1298917008423	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1298917008424	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1298917008425	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1298917008426	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1298917008427	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1298917008428	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1298917008429	intersubunit interface [polypeptide binding]; other site
1298917008430	active site
1298917008431	zinc binding site [ion binding]; other site
1298917008432	Na+ binding site [ion binding]; other site
1298917008433	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
1298917008434	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1298917008435	active site
1298917008436	phosphorylation site [posttranslational modification]
1298917008437	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1298917008438	active site
1298917008439	P-loop; other site
1298917008440	phosphorylation site [posttranslational modification]
1298917008441	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1298917008442	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1298917008443	putative NAD(P) binding site [chemical binding]; other site
1298917008444	catalytic Zn binding site [ion binding]; other site
1298917008445	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1298917008446	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1298917008447	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917008448	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1298917008449	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1298917008450	putative SAM binding site [chemical binding]; other site
1298917008451	putative homodimer interface [polypeptide binding]; other site
1298917008452	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1298917008453	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
1298917008454	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1298917008455	putative ligand binding site [chemical binding]; other site
1298917008456	TIGR00252 family protein; Region: TIGR00252
1298917008457	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1298917008458	dimer interface [polypeptide binding]; other site
1298917008459	active site
1298917008460	outer membrane lipoprotein; Provisional; Region: PRK11023
1298917008461	BON domain; Region: BON; pfam04972
1298917008462	BON domain; Region: BON; pfam04972
1298917008463	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1298917008464	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1298917008465	NAD binding site [chemical binding]; other site
1298917008466	active site
1298917008467	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1298917008468	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1298917008469	proposed catalytic triad [active]
1298917008470	conserved cys residue [active]
1298917008471	hypothetical protein; Provisional; Region: PRK03467
1298917008472	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1298917008473	GIY-YIG motif/motif A; other site
1298917008474	putative active site [active]
1298917008475	putative metal binding site [ion binding]; other site
1298917008476	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1298917008477	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917008478	Coenzyme A binding pocket [chemical binding]; other site
1298917008479	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1298917008480	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1298917008481	Peptidase family U32; Region: Peptidase_U32; pfam01136
1298917008482	putative protease; Provisional; Region: PRK15447
1298917008483	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1298917008484	hypothetical protein; Provisional; Region: PRK10508
1298917008485	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1298917008486	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1298917008487	tryptophan permease; Provisional; Region: PRK10483
1298917008488	aromatic amino acid transport protein; Region: araaP; TIGR00837
1298917008489	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1298917008490	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1298917008491	ATP binding site [chemical binding]; other site
1298917008492	Mg++ binding site [ion binding]; other site
1298917008493	motif III; other site
1298917008494	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917008495	nucleotide binding region [chemical binding]; other site
1298917008496	ATP-binding site [chemical binding]; other site
1298917008497	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1298917008498	putative RNA binding site [nucleotide binding]; other site
1298917008499	lipoprotein NlpI; Provisional; Region: PRK11189
1298917008500	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1298917008501	binding surface
1298917008502	TPR motif; other site
1298917008503	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1298917008504	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1298917008505	RNase E interface [polypeptide binding]; other site
1298917008506	trimer interface [polypeptide binding]; other site
1298917008507	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1298917008508	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1298917008509	RNase E interface [polypeptide binding]; other site
1298917008510	trimer interface [polypeptide binding]; other site
1298917008511	active site
1298917008512	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1298917008513	putative nucleic acid binding region [nucleotide binding]; other site
1298917008514	G-X-X-G motif; other site
1298917008515	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1298917008516	RNA binding site [nucleotide binding]; other site
1298917008517	domain interface; other site
1298917008518	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1298917008519	16S/18S rRNA binding site [nucleotide binding]; other site
1298917008520	S13e-L30e interaction site [polypeptide binding]; other site
1298917008521	25S rRNA binding site [nucleotide binding]; other site
1298917008522	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1298917008523	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1298917008524	RNA binding site [nucleotide binding]; other site
1298917008525	active site
1298917008526	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1298917008527	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1298917008528	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1298917008529	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1298917008530	translation initiation factor IF-2; Region: IF-2; TIGR00487
1298917008531	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1298917008532	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1298917008533	G1 box; other site
1298917008534	putative GEF interaction site [polypeptide binding]; other site
1298917008535	GTP/Mg2+ binding site [chemical binding]; other site
1298917008536	Switch I region; other site
1298917008537	G2 box; other site
1298917008538	G3 box; other site
1298917008539	Switch II region; other site
1298917008540	G4 box; other site
1298917008541	G5 box; other site
1298917008542	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1298917008543	Translation-initiation factor 2; Region: IF-2; pfam11987
1298917008544	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1298917008545	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1298917008546	NusA N-terminal domain; Region: NusA_N; pfam08529
1298917008547	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1298917008548	RNA binding site [nucleotide binding]; other site
1298917008549	homodimer interface [polypeptide binding]; other site
1298917008550	NusA-like KH domain; Region: KH_5; pfam13184
1298917008551	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1298917008552	G-X-X-G motif; other site
1298917008553	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1298917008554	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1298917008555	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1298917008556	Sm and related proteins; Region: Sm_like; cl00259
1298917008557	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1298917008558	putative oligomer interface [polypeptide binding]; other site
1298917008559	putative RNA binding site [nucleotide binding]; other site
1298917008560	argininosuccinate synthase; Validated; Region: PRK05370
1298917008561	argininosuccinate synthase; Provisional; Region: PRK13820
1298917008562	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1298917008563	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1298917008564	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1298917008565	active site
1298917008566	substrate binding site [chemical binding]; other site
1298917008567	metal binding site [ion binding]; metal-binding site
1298917008568	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1298917008569	dihydropteroate synthase; Region: DHPS; TIGR01496
1298917008570	substrate binding pocket [chemical binding]; other site
1298917008571	dimer interface [polypeptide binding]; other site
1298917008572	inhibitor binding site; inhibition site
1298917008573	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1298917008574	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917008575	Walker A motif; other site
1298917008576	ATP binding site [chemical binding]; other site
1298917008577	Walker B motif; other site
1298917008578	arginine finger; other site
1298917008579	Peptidase family M41; Region: Peptidase_M41; pfam01434
1298917008580	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1298917008581	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917008582	S-adenosylmethionine binding site [chemical binding]; other site
1298917008583	RNA-binding protein YhbY; Provisional; Region: PRK10343
1298917008584	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1298917008585	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1298917008586	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1298917008587	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1298917008588	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1298917008589	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1298917008590	EamA-like transporter family; Region: EamA; pfam00892
1298917008591	EamA-like transporter family; Region: EamA; pfam00892
1298917008592	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1298917008593	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1298917008594	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1298917008595	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1298917008596	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1298917008597	substrate binding pocket [chemical binding]; other site
1298917008598	chain length determination region; other site
1298917008599	substrate-Mg2+ binding site; other site
1298917008600	catalytic residues [active]
1298917008601	aspartate-rich region 1; other site
1298917008602	active site lid residues [active]
1298917008603	aspartate-rich region 2; other site
1298917008604	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1298917008605	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1298917008606	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1298917008607	hinge; other site
1298917008608	active site
1298917008609	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1298917008610	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1298917008611	anti sigma factor interaction site; other site
1298917008612	regulatory phosphorylation site [posttranslational modification]; other site
1298917008613	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1298917008614	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1298917008615	mce related protein; Region: MCE; pfam02470
1298917008616	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1298917008617	conserved hypothetical integral membrane protein; Region: TIGR00056
1298917008618	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1298917008619	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1298917008620	Walker A/P-loop; other site
1298917008621	ATP binding site [chemical binding]; other site
1298917008622	Q-loop/lid; other site
1298917008623	ABC transporter signature motif; other site
1298917008624	Walker B; other site
1298917008625	D-loop; other site
1298917008626	H-loop/switch region; other site
1298917008627	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1298917008628	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1298917008629	putative active site [active]
1298917008630	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1298917008631	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1298917008632	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1298917008633	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1298917008634	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1298917008635	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1298917008636	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1298917008637	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1298917008638	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1298917008639	Walker A/P-loop; other site
1298917008640	ATP binding site [chemical binding]; other site
1298917008641	Q-loop/lid; other site
1298917008642	ABC transporter signature motif; other site
1298917008643	Walker B; other site
1298917008644	D-loop; other site
1298917008645	H-loop/switch region; other site
1298917008646	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1298917008647	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1298917008648	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1298917008649	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1298917008650	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1298917008651	30S subunit binding site; other site
1298917008652	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1298917008653	active site
1298917008654	phosphorylation site [posttranslational modification]
1298917008655	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
1298917008656	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1298917008657	dimerization domain swap beta strand [polypeptide binding]; other site
1298917008658	regulatory protein interface [polypeptide binding]; other site
1298917008659	active site
1298917008660	regulatory phosphorylation site [posttranslational modification]; other site
1298917008661	hypothetical protein; Provisional; Region: PRK10345
1298917008662	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1298917008663	Transglycosylase; Region: Transgly; cl17702
1298917008664	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1298917008665	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1298917008666	conserved cys residue [active]
1298917008667	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1298917008668	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1298917008669	putative active site [active]
1298917008670	heme pocket [chemical binding]; other site
1298917008671	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917008672	dimer interface [polypeptide binding]; other site
1298917008673	phosphorylation site [posttranslational modification]
1298917008674	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917008675	ATP binding site [chemical binding]; other site
1298917008676	Mg2+ binding site [ion binding]; other site
1298917008677	G-X-G motif; other site
1298917008678	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917008679	active site
1298917008680	phosphorylation site [posttranslational modification]
1298917008681	intermolecular recognition site; other site
1298917008682	dimerization interface [polypeptide binding]; other site
1298917008683	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1298917008684	putative binding surface; other site
1298917008685	active site
1298917008686	radical SAM protein, TIGR01212 family; Region: TIGR01212
1298917008687	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917008688	FeS/SAM binding site; other site
1298917008689	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1298917008690	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1298917008691	active site
1298917008692	dimer interface [polypeptide binding]; other site
1298917008693	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1298917008694	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1298917008695	active site
1298917008696	FMN binding site [chemical binding]; other site
1298917008697	substrate binding site [chemical binding]; other site
1298917008698	3Fe-4S cluster binding site [ion binding]; other site
1298917008699	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1298917008700	domain interface; other site
1298917008701	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1298917008702	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1298917008703	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917008704	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1298917008705	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1298917008706	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1298917008707	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1298917008708	Na binding site [ion binding]; other site
1298917008709	putative substrate binding site [chemical binding]; other site
1298917008710	cytosine deaminase; Provisional; Region: PRK09230
1298917008711	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1298917008712	active site
1298917008713	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1298917008714	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1298917008715	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1298917008716	nucleotide binding site [chemical binding]; other site
1298917008717	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1298917008718	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1298917008719	putative active site cavity [active]
1298917008720	putative sialic acid transporter; Provisional; Region: PRK03893
1298917008721	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917008722	putative substrate translocation pore; other site
1298917008723	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1298917008724	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1298917008725	inhibitor site; inhibition site
1298917008726	active site
1298917008727	dimer interface [polypeptide binding]; other site
1298917008728	catalytic residue [active]
1298917008729	transcriptional regulator NanR; Provisional; Region: PRK03837
1298917008730	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917008731	DNA-binding site [nucleotide binding]; DNA binding site
1298917008732	FCD domain; Region: FCD; pfam07729
1298917008733	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
1298917008734	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1298917008735	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1298917008736	C-terminal domain interface [polypeptide binding]; other site
1298917008737	putative GSH binding site (G-site) [chemical binding]; other site
1298917008738	dimer interface [polypeptide binding]; other site
1298917008739	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1298917008740	dimer interface [polypeptide binding]; other site
1298917008741	N-terminal domain interface [polypeptide binding]; other site
1298917008742	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1298917008743	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1298917008744	23S rRNA interface [nucleotide binding]; other site
1298917008745	L3 interface [polypeptide binding]; other site
1298917008746	Predicted ATPase [General function prediction only]; Region: COG1485
1298917008747	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1298917008748	hypothetical protein; Provisional; Region: PRK11677
1298917008749	serine endoprotease; Provisional; Region: PRK10139
1298917008750	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1298917008751	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1298917008752	protein binding site [polypeptide binding]; other site
1298917008753	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1298917008754	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1298917008755	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1298917008756	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1298917008757	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1298917008758	active site
1298917008759	catalytic residues [active]
1298917008760	metal binding site [ion binding]; metal-binding site
1298917008761	homodimer binding site [polypeptide binding]; other site
1298917008762	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1298917008763	carboxyltransferase (CT) interaction site; other site
1298917008764	biotinylation site [posttranslational modification]; other site
1298917008765	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1298917008766	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
1298917008767	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
1298917008768	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1298917008769	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1298917008770	transmembrane helices; other site
1298917008771	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1298917008772	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917008773	DNA-binding site [nucleotide binding]; DNA binding site
1298917008774	FCD domain; Region: FCD; pfam07729
1298917008775	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1298917008776	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917008777	DNA-binding site [nucleotide binding]; DNA binding site
1298917008778	malate dehydrogenase; Provisional; Region: PRK05086
1298917008779	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1298917008780	NAD binding site [chemical binding]; other site
1298917008781	dimerization interface [polypeptide binding]; other site
1298917008782	Substrate binding site [chemical binding]; other site
1298917008783	arginine repressor; Provisional; Region: PRK05066
1298917008784	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1298917008785	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1298917008786	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1298917008787	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1298917008788	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1298917008789	RNAase interaction site [polypeptide binding]; other site
1298917008790	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1298917008791	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1298917008792	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1298917008793	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1298917008794	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917008795	efflux system membrane protein; Provisional; Region: PRK11594
1298917008796	transcriptional regulator; Provisional; Region: PRK10632
1298917008797	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917008798	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1298917008799	putative effector binding pocket; other site
1298917008800	dimerization interface [polypeptide binding]; other site
1298917008801	protease TldD; Provisional; Region: tldD; PRK10735
1298917008802	hypothetical protein; Provisional; Region: PRK10899
1298917008803	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1298917008804	ribonuclease G; Provisional; Region: PRK11712
1298917008805	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1298917008806	homodimer interface [polypeptide binding]; other site
1298917008807	oligonucleotide binding site [chemical binding]; other site
1298917008808	Maf-like protein; Region: Maf; pfam02545
1298917008809	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1298917008810	active site
1298917008811	dimer interface [polypeptide binding]; other site
1298917008812	rod shape-determining protein MreD; Provisional; Region: PRK11060
1298917008813	rod shape-determining protein MreC; Region: mreC; TIGR00219
1298917008814	rod shape-determining protein MreC; Region: MreC; pfam04085
1298917008815	rod shape-determining protein MreB; Provisional; Region: PRK13927
1298917008816	MreB and similar proteins; Region: MreB_like; cd10225
1298917008817	nucleotide binding site [chemical binding]; other site
1298917008818	Mg binding site [ion binding]; other site
1298917008819	putative protofilament interaction site [polypeptide binding]; other site
1298917008820	RodZ interaction site [polypeptide binding]; other site
1298917008821	regulatory protein CsrD; Provisional; Region: PRK11059
1298917008822	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1298917008823	metal binding site [ion binding]; metal-binding site
1298917008824	active site
1298917008825	I-site; other site
1298917008826	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917008827	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1298917008828	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1298917008829	Moco binding site; other site
1298917008830	metal coordination site [ion binding]; other site
1298917008831	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1298917008832	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1298917008833	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1298917008834	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1298917008835	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1298917008836	hypothetical protein; Provisional; Region: PRK10633
1298917008837	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1298917008838	Na binding site [ion binding]; other site
1298917008839	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1298917008840	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1298917008841	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1298917008842	FMN binding site [chemical binding]; other site
1298917008843	active site
1298917008844	catalytic residues [active]
1298917008845	substrate binding site [chemical binding]; other site
1298917008846	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1298917008847	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1298917008848	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1298917008849	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917008850	DNA methylase; Region: N6_N4_Mtase; pfam01555
1298917008851	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
1298917008852	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1298917008853	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1298917008854	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1298917008855	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1298917008856	metal binding site [ion binding]; metal-binding site
1298917008857	active site
1298917008858	I-site; other site
1298917008859	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917008860	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
1298917008861	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917008862	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1298917008863	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1298917008864	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1298917008865	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917008866	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1298917008867	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1298917008868	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1298917008869	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1298917008870	purine monophosphate binding site [chemical binding]; other site
1298917008871	dimer interface [polypeptide binding]; other site
1298917008872	putative catalytic residues [active]
1298917008873	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1298917008874	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1298917008875	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1298917008876	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1298917008877	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1298917008878	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
1298917008879	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917008880	active site
1298917008881	phosphorylation site [posttranslational modification]
1298917008882	intermolecular recognition site; other site
1298917008883	dimerization interface [polypeptide binding]; other site
1298917008884	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917008885	Walker A motif; other site
1298917008886	ATP binding site [chemical binding]; other site
1298917008887	Walker B motif; other site
1298917008888	arginine finger; other site
1298917008889	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1298917008890	sensor protein ZraS; Provisional; Region: PRK10364
1298917008891	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917008892	dimer interface [polypeptide binding]; other site
1298917008893	phosphorylation site [posttranslational modification]
1298917008894	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917008895	ATP binding site [chemical binding]; other site
1298917008896	Mg2+ binding site [ion binding]; other site
1298917008897	G-X-G motif; other site
1298917008898	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1298917008899	dimer interface [polypeptide binding]; other site
1298917008900	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1298917008901	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1298917008902	IHF dimer interface [polypeptide binding]; other site
1298917008903	IHF - DNA interface [nucleotide binding]; other site
1298917008904	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1298917008905	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1298917008906	Active_site [active]
1298917008907	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1298917008908	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1298917008909	substrate binding site [chemical binding]; other site
1298917008910	active site
1298917008911	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1298917008912	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1298917008913	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1298917008914	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1298917008915	putative NADH binding site [chemical binding]; other site
1298917008916	putative active site [active]
1298917008917	nudix motif; other site
1298917008918	putative metal binding site [ion binding]; other site
1298917008919	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
1298917008920	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1298917008921	ThiC-associated domain; Region: ThiC-associated; pfam13667
1298917008922	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1298917008923	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1298917008924	thiamine phosphate binding site [chemical binding]; other site
1298917008925	active site
1298917008926	pyrophosphate binding site [ion binding]; other site
1298917008927	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1298917008928	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1298917008929	ATP binding site [chemical binding]; other site
1298917008930	substrate interface [chemical binding]; other site
1298917008931	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1298917008932	thiS-thiF/thiG interaction site; other site
1298917008933	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1298917008934	ThiS interaction site; other site
1298917008935	putative active site [active]
1298917008936	tetramer interface [polypeptide binding]; other site
1298917008937	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1298917008938	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917008939	FeS/SAM binding site; other site
1298917008940	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1298917008941	type III secretion system protein; Provisional; Region: PRK15384
1298917008942	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
1298917008943	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1298917008944	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1298917008945	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1298917008946	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1298917008947	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1298917008948	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1298917008949	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1298917008950	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1298917008951	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1298917008952	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1298917008953	DNA binding site [nucleotide binding]
1298917008954	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1298917008955	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1298917008956	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1298917008957	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1298917008958	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1298917008959	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1298917008960	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1298917008961	RPB3 interaction site [polypeptide binding]; other site
1298917008962	RPB1 interaction site [polypeptide binding]; other site
1298917008963	RPB11 interaction site [polypeptide binding]; other site
1298917008964	RPB10 interaction site [polypeptide binding]; other site
1298917008965	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1298917008966	core dimer interface [polypeptide binding]; other site
1298917008967	peripheral dimer interface [polypeptide binding]; other site
1298917008968	L10 interface [polypeptide binding]; other site
1298917008969	L11 interface [polypeptide binding]; other site
1298917008970	putative EF-Tu interaction site [polypeptide binding]; other site
1298917008971	putative EF-G interaction site [polypeptide binding]; other site
1298917008972	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1298917008973	23S rRNA interface [nucleotide binding]; other site
1298917008974	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1298917008975	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1298917008976	mRNA/rRNA interface [nucleotide binding]; other site
1298917008977	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1298917008978	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1298917008979	23S rRNA interface [nucleotide binding]; other site
1298917008980	L7/L12 interface [polypeptide binding]; other site
1298917008981	putative thiostrepton binding site; other site
1298917008982	L25 interface [polypeptide binding]; other site
1298917008983	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1298917008984	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1298917008985	putative homodimer interface [polypeptide binding]; other site
1298917008986	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1298917008987	heterodimer interface [polypeptide binding]; other site
1298917008988	homodimer interface [polypeptide binding]; other site
1298917008989	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1298917008990	pantothenate kinase; Provisional; Region: PRK05439
1298917008991	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1298917008992	ATP-binding site [chemical binding]; other site
1298917008993	CoA-binding site [chemical binding]; other site
1298917008994	Mg2+-binding site [ion binding]; other site
1298917008995	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1298917008996	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1298917008997	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1298917008998	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1298917008999	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1298917009000	FAD binding domain; Region: FAD_binding_4; pfam01565
1298917009001	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1298917009002	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1298917009003	potassium transporter; Provisional; Region: PRK10750
1298917009004	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1298917009005	proline dipeptidase; Provisional; Region: PRK13607
1298917009006	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1298917009007	active site
1298917009008	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1298917009009	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1298917009010	substrate binding site [chemical binding]; other site
1298917009011	oxyanion hole (OAH) forming residues; other site
1298917009012	trimer interface [polypeptide binding]; other site
1298917009013	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1298917009014	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1298917009015	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1298917009016	FMN reductase; Validated; Region: fre; PRK08051
1298917009017	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1298917009018	FAD binding pocket [chemical binding]; other site
1298917009019	FAD binding motif [chemical binding]; other site
1298917009020	phosphate binding motif [ion binding]; other site
1298917009021	beta-alpha-beta structure motif; other site
1298917009022	NAD binding pocket [chemical binding]; other site
1298917009023	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1298917009024	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1298917009025	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1298917009026	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
1298917009027	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1298917009028	active site
1298917009029	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1298917009030	sec-independent translocase; Provisional; Region: PRK01770
1298917009031	sec-independent translocase; Provisional; Region: tatB; PRK00404
1298917009032	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1298917009033	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1298917009034	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1298917009035	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1298917009036	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1298917009037	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1298917009038	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917009039	S-adenosylmethionine binding site [chemical binding]; other site
1298917009040	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
1298917009041	DNA recombination protein RmuC; Provisional; Region: PRK10361
1298917009042	RmuC family; Region: RmuC; pfam02646
1298917009043	uridine phosphorylase; Provisional; Region: PRK11178
1298917009044	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
1298917009045	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1298917009046	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1298917009047	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917009048	FeS/SAM binding site; other site
1298917009049	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1298917009050	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1298917009051	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1298917009052	THF binding site; other site
1298917009053	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1298917009054	substrate binding site [chemical binding]; other site
1298917009055	THF binding site; other site
1298917009056	zinc-binding site [ion binding]; other site
1298917009057	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1298917009058	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917009059	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1298917009060	putative dimerization interface [polypeptide binding]; other site
1298917009061	putative hydrolase; Provisional; Region: PRK10976
1298917009062	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917009063	active site
1298917009064	motif I; other site
1298917009065	motif II; other site
1298917009066	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917009067	lysophospholipase L2; Provisional; Region: PRK10749
1298917009068	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1298917009069	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1298917009070	threonine efflux system; Provisional; Region: PRK10229
1298917009071	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1298917009072	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1298917009073	ATP binding site [chemical binding]; other site
1298917009074	putative Mg++ binding site [ion binding]; other site
1298917009075	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917009076	nucleotide binding region [chemical binding]; other site
1298917009077	ATP-binding site [chemical binding]; other site
1298917009078	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1298917009079	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1298917009080	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1298917009081	dimerization interface [polypeptide binding]; other site
1298917009082	substrate binding site [chemical binding]; other site
1298917009083	active site
1298917009084	calcium binding site [ion binding]; other site
1298917009085	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1298917009086	CoenzymeA binding site [chemical binding]; other site
1298917009087	subunit interaction site [polypeptide binding]; other site
1298917009088	PHB binding site; other site
1298917009089	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1298917009090	EamA-like transporter family; Region: EamA; cl17759
1298917009091	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1298917009092	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1298917009093	Cl binding site [ion binding]; other site
1298917009094	oligomer interface [polypeptide binding]; other site
1298917009095	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1298917009096	Part of AAA domain; Region: AAA_19; pfam13245
1298917009097	Family description; Region: UvrD_C_2; pfam13538
1298917009098	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1298917009099	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917009100	motif II; other site
1298917009101	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1298917009102	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1298917009103	active site
1298917009104	Int/Topo IB signature motif; other site
1298917009105	hypothetical protein; Provisional; Region: PRK10963
1298917009106	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1298917009107	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1298917009108	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1298917009109	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1298917009110	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
1298917009111	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1298917009112	putative iron binding site [ion binding]; other site
1298917009113	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1298917009114	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1298917009115	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1298917009116	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1298917009117	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1298917009118	domain interfaces; other site
1298917009119	active site
1298917009120	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1298917009121	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1298917009122	active site
1298917009123	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1298917009124	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1298917009125	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1298917009126	HemY protein N-terminus; Region: HemY_N; pfam07219
1298917009127	putative transport protein YifK; Provisional; Region: PRK10746
1298917009128	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1298917009129	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1298917009130	putative common antigen polymerase; Provisional; Region: PRK02975
1298917009131	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1298917009132	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1298917009133	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1298917009134	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1298917009135	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1298917009136	inhibitor-cofactor binding pocket; inhibition site
1298917009137	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917009138	catalytic residue [active]
1298917009139	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
1298917009140	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1298917009141	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1298917009142	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
1298917009143	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1298917009144	NAD binding site [chemical binding]; other site
1298917009145	substrate binding site [chemical binding]; other site
1298917009146	homodimer interface [polypeptide binding]; other site
1298917009147	active site
1298917009148	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1298917009149	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1298917009150	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1298917009151	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1298917009152	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1298917009153	active site
1298917009154	homodimer interface [polypeptide binding]; other site
1298917009155	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1298917009156	Chain length determinant protein; Region: Wzz; pfam02706
1298917009157	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1298917009158	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1298917009159	Mg++ binding site [ion binding]; other site
1298917009160	putative catalytic motif [active]
1298917009161	substrate binding site [chemical binding]; other site
1298917009162	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1298917009163	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1298917009164	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1298917009165	RNA binding site [nucleotide binding]; other site
1298917009166	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1298917009167	multimer interface [polypeptide binding]; other site
1298917009168	Walker A motif; other site
1298917009169	ATP binding site [chemical binding]; other site
1298917009170	Walker B motif; other site
1298917009171	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1298917009172	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1298917009173	catalytic residues [active]
1298917009174	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1298917009175	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1298917009176	ATP binding site [chemical binding]; other site
1298917009177	Mg++ binding site [ion binding]; other site
1298917009178	motif III; other site
1298917009179	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917009180	nucleotide binding region [chemical binding]; other site
1298917009181	ATP-binding site [chemical binding]; other site
1298917009182	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1298917009183	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1298917009184	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1298917009185	Part of AAA domain; Region: AAA_19; pfam13245
1298917009186	Family description; Region: UvrD_C_2; pfam13538
1298917009187	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1298917009188	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1298917009189	ketol-acid reductoisomerase; Validated; Region: PRK05225
1298917009190	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1298917009191	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1298917009192	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1298917009193	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
1298917009194	Phage-related protein [Function unknown]; Region: COG4679
1298917009195	threonine dehydratase; Reviewed; Region: PRK09224
1298917009196	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1298917009197	tetramer interface [polypeptide binding]; other site
1298917009198	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917009199	catalytic residue [active]
1298917009200	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1298917009201	putative Ile/Val binding site [chemical binding]; other site
1298917009202	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1298917009203	putative Ile/Val binding site [chemical binding]; other site
1298917009204	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1298917009205	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1298917009206	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1298917009207	homodimer interface [polypeptide binding]; other site
1298917009208	substrate-cofactor binding pocket; other site
1298917009209	catalytic residue [active]
1298917009210	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1298917009211	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1298917009212	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1298917009213	PYR/PP interface [polypeptide binding]; other site
1298917009214	dimer interface [polypeptide binding]; other site
1298917009215	TPP binding site [chemical binding]; other site
1298917009216	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1298917009217	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1298917009218	TPP-binding site [chemical binding]; other site
1298917009219	dimer interface [polypeptide binding]; other site
1298917009220	putative ATP-dependent protease; Provisional; Region: PRK09862
1298917009221	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1298917009222	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917009223	Walker A motif; other site
1298917009224	ATP binding site [chemical binding]; other site
1298917009225	Walker B motif; other site
1298917009226	arginine finger; other site
1298917009227	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1298917009228	hypothetical protein; Provisional; Region: PRK11027
1298917009229	transcriptional regulator HdfR; Provisional; Region: PRK03601
1298917009230	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917009231	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1298917009232	dimerization interface [polypeptide binding]; other site
1298917009233	glutamate racemase; Provisional; Region: PRK00865
1298917009234	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1298917009235	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1298917009236	N-terminal plug; other site
1298917009237	ligand-binding site [chemical binding]; other site
1298917009238	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1298917009239	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917009240	S-adenosylmethionine binding site [chemical binding]; other site
1298917009241	hypothetical protein; Provisional; Region: PRK11056
1298917009242	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1298917009243	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917009244	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1298917009245	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917009246	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1298917009247	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1298917009248	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917009249	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1298917009250	dimerization interface [polypeptide binding]; other site
1298917009251	argininosuccinate lyase; Provisional; Region: PRK04833
1298917009252	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1298917009253	active sites [active]
1298917009254	tetramer interface [polypeptide binding]; other site
1298917009255	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1298917009256	nucleotide binding site [chemical binding]; other site
1298917009257	N-acetyl-L-glutamate binding site [chemical binding]; other site
1298917009258	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1298917009259	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1298917009260	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1298917009261	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1298917009262	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1298917009263	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917009264	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1298917009265	active site
1298917009266	P-loop; other site
1298917009267	phosphorylation site [posttranslational modification]
1298917009268	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917009269	FeS/SAM binding site; other site
1298917009270	pyruvate formate lyase II activase; Provisional; Region: PRK10076
1298917009271	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
1298917009272	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1298917009273	dimer interface [polypeptide binding]; other site
1298917009274	active site
1298917009275	glycine loop; other site
1298917009276	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1298917009277	active site
1298917009278	P-loop; other site
1298917009279	phosphorylation site [posttranslational modification]
1298917009280	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
1298917009281	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1298917009282	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1298917009283	dimerization domain swap beta strand [polypeptide binding]; other site
1298917009284	regulatory protein interface [polypeptide binding]; other site
1298917009285	active site
1298917009286	regulatory phosphorylation site [posttranslational modification]; other site
1298917009287	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1298917009288	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1298917009289	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1298917009290	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1298917009291	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1298917009292	active site
1298917009293	phosphorylation site [posttranslational modification]
1298917009294	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1298917009295	active site
1298917009296	intersubunit interactions; other site
1298917009297	catalytic residue [active]
1298917009298	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
1298917009299	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1298917009300	FAD binding site [chemical binding]; other site
1298917009301	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1298917009302	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917009303	DNA-binding site [nucleotide binding]; DNA binding site
1298917009304	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917009305	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917009306	homodimer interface [polypeptide binding]; other site
1298917009307	catalytic residue [active]
1298917009308	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
1298917009309	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1298917009310	active site
1298917009311	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1298917009312	dimer interface [polypeptide binding]; other site
1298917009313	substrate binding site [chemical binding]; other site
1298917009314	catalytic residues [active]
1298917009315	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
1298917009316	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1298917009317	dimer interface [polypeptide binding]; other site
1298917009318	active site
1298917009319	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1298917009320	folate binding site [chemical binding]; other site
1298917009321	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1298917009322	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1298917009323	active site
1298917009324	metal binding site [ion binding]; metal-binding site
1298917009325	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1298917009326	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1298917009327	mechanosensitive channel MscS; Provisional; Region: PRK10334
1298917009328	Conserved TM helix; Region: TM_helix; pfam05552
1298917009329	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1298917009330	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1298917009331	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1298917009332	putative catalytic residues [active]
1298917009333	putative nucleotide binding site [chemical binding]; other site
1298917009334	putative aspartate binding site [chemical binding]; other site
1298917009335	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1298917009336	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1298917009337	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1298917009338	cystathionine gamma-synthase; Provisional; Region: PRK08045
1298917009339	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1298917009340	homodimer interface [polypeptide binding]; other site
1298917009341	substrate-cofactor binding pocket; other site
1298917009342	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917009343	catalytic residue [active]
1298917009344	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1298917009345	dimerization interface [polypeptide binding]; other site
1298917009346	DNA binding site [nucleotide binding]
1298917009347	corepressor binding sites; other site
1298917009348	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1298917009349	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
1298917009350	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1298917009351	primosome assembly protein PriA; Validated; Region: PRK05580
1298917009352	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1298917009353	ATP binding site [chemical binding]; other site
1298917009354	putative Mg++ binding site [ion binding]; other site
1298917009355	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1298917009356	ATP-binding site [chemical binding]; other site
1298917009357	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917009358	DNA binding site [nucleotide binding]
1298917009359	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1298917009360	domain linker motif; other site
1298917009361	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1298917009362	dimerization interface [polypeptide binding]; other site
1298917009363	ligand binding site [chemical binding]; other site
1298917009364	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1298917009365	active site
1298917009366	HslU subunit interaction site [polypeptide binding]; other site
1298917009367	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1298917009368	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917009369	Walker A motif; other site
1298917009370	ATP binding site [chemical binding]; other site
1298917009371	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1298917009372	Walker B motif; other site
1298917009373	arginine finger; other site
1298917009374	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1298917009375	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
1298917009376	UbiA prenyltransferase family; Region: UbiA; pfam01040
1298917009377	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1298917009378	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1298917009379	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1298917009380	amphipathic channel; other site
1298917009381	Asn-Pro-Ala signature motifs; other site
1298917009382	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1298917009383	nucleotide binding site [chemical binding]; other site
1298917009384	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
1298917009385	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1298917009386	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1298917009387	FAD binding pocket [chemical binding]; other site
1298917009388	FAD binding motif [chemical binding]; other site
1298917009389	phosphate binding motif [ion binding]; other site
1298917009390	beta-alpha-beta structure motif; other site
1298917009391	NAD binding pocket [chemical binding]; other site
1298917009392	Predicted membrane protein [Function unknown]; Region: COG3152
1298917009393	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1298917009394	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1298917009395	triosephosphate isomerase; Provisional; Region: PRK14567
1298917009396	substrate binding site [chemical binding]; other site
1298917009397	dimer interface [polypeptide binding]; other site
1298917009398	catalytic triad [active]
1298917009399	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1298917009400	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1298917009401	substrate binding site [chemical binding]; other site
1298917009402	hexamer interface [polypeptide binding]; other site
1298917009403	metal binding site [ion binding]; metal-binding site
1298917009404	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1298917009405	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1298917009406	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1298917009407	putative active site; other site
1298917009408	catalytic residue [active]
1298917009409	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1298917009410	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1298917009411	ligand binding site [chemical binding]; other site
1298917009412	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1298917009413	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1298917009414	TM-ABC transporter signature motif; other site
1298917009415	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1298917009416	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1298917009417	TM-ABC transporter signature motif; other site
1298917009418	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1298917009419	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1298917009420	Walker A/P-loop; other site
1298917009421	ATP binding site [chemical binding]; other site
1298917009422	Q-loop/lid; other site
1298917009423	ABC transporter signature motif; other site
1298917009424	Walker B; other site
1298917009425	D-loop; other site
1298917009426	H-loop/switch region; other site
1298917009427	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1298917009428	transcriptional regulator LsrR; Provisional; Region: PRK15418
1298917009429	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1298917009430	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1298917009431	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1298917009432	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
1298917009433	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1298917009434	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917009435	DNA-binding site [nucleotide binding]; DNA binding site
1298917009436	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
1298917009437	UTRA domain; Region: UTRA; pfam07702
1298917009438	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1298917009439	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1298917009440	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1298917009441	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1298917009442	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1298917009443	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1298917009444	active site
1298917009445	ADP/pyrophosphate binding site [chemical binding]; other site
1298917009446	dimerization interface [polypeptide binding]; other site
1298917009447	allosteric effector site; other site
1298917009448	fructose-1,6-bisphosphate binding site; other site
1298917009449	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1298917009450	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1298917009451	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1298917009452	dimer interface [polypeptide binding]; other site
1298917009453	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1298917009454	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917009455	active site
1298917009456	intermolecular recognition site; other site
1298917009457	dimerization interface [polypeptide binding]; other site
1298917009458	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917009459	DNA binding site [nucleotide binding]
1298917009460	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1298917009461	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917009462	dimerization interface [polypeptide binding]; other site
1298917009463	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917009464	dimer interface [polypeptide binding]; other site
1298917009465	phosphorylation site [posttranslational modification]
1298917009466	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917009467	ATP binding site [chemical binding]; other site
1298917009468	Mg2+ binding site [ion binding]; other site
1298917009469	G-X-G motif; other site
1298917009470	SnoaL-like domain; Region: SnoaL_2; pfam12680
1298917009471	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1298917009472	MOSC domain; Region: MOSC; pfam03473
1298917009473	3-alpha domain; Region: 3-alpha; pfam03475
1298917009474	superoxide dismutase; Provisional; Region: PRK10925
1298917009475	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1298917009476	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1298917009477	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1298917009478	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1298917009479	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1298917009480	DctM-like transporters; Region: DctM; pfam06808
1298917009481	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
1298917009482	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1298917009483	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
1298917009484	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1298917009485	transcriptional activator RhaR; Provisional; Region: PRK13502
1298917009486	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1298917009487	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917009488	transcriptional activator RhaS; Provisional; Region: PRK13503
1298917009489	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1298917009490	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917009491	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917009492	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1298917009493	N- and C-terminal domain interface [polypeptide binding]; other site
1298917009494	active site
1298917009495	putative catalytic site [active]
1298917009496	metal binding site [ion binding]; metal-binding site
1298917009497	ATP binding site [chemical binding]; other site
1298917009498	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1298917009499	carbohydrate binding site [chemical binding]; other site
1298917009500	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1298917009501	intersubunit interface [polypeptide binding]; other site
1298917009502	active site
1298917009503	Zn2+ binding site [ion binding]; other site
1298917009504	lactaldehyde reductase; Region: lactal_redase; TIGR02638
1298917009505	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1298917009506	dimer interface [polypeptide binding]; other site
1298917009507	active site
1298917009508	metal binding site [ion binding]; metal-binding site
1298917009509	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1298917009510	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917009511	non-specific DNA binding site [nucleotide binding]; other site
1298917009512	salt bridge; other site
1298917009513	sequence-specific DNA binding site [nucleotide binding]; other site
1298917009514	Cupin domain; Region: Cupin_2; cl17218
1298917009515	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1298917009516	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1298917009517	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1298917009518	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1298917009519	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1298917009520	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1298917009521	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1298917009522	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1298917009523	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1298917009524	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1298917009525	molybdopterin cofactor binding site; other site
1298917009526	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1298917009527	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1298917009528	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1298917009529	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1298917009530	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1298917009531	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1298917009532	Predicted transcriptional regulator [Transcription]; Region: COG2944
1298917009533	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917009534	non-specific DNA binding site [nucleotide binding]; other site
1298917009535	salt bridge; other site
1298917009536	sequence-specific DNA binding site [nucleotide binding]; other site
1298917009537	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1298917009538	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
1298917009539	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1298917009540	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
1298917009541	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917009542	non-specific DNA binding site [nucleotide binding]; other site
1298917009543	salt bridge; other site
1298917009544	sequence-specific DNA binding site [nucleotide binding]; other site
1298917009545	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917009546	Coenzyme A binding pocket [chemical binding]; other site
1298917009547	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1298917009548	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1298917009549	putative active site [active]
1298917009550	dimerization interface [polypeptide binding]; other site
1298917009551	putative tRNAtyr binding site [nucleotide binding]; other site
1298917009552	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1298917009553	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917009554	motif II; other site
1298917009555	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1298917009556	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1298917009557	putative DNA binding site [nucleotide binding]; other site
1298917009558	putative Zn2+ binding site [ion binding]; other site
1298917009559	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917009560	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1298917009561	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
1298917009562	substrate binding site [chemical binding]; other site
1298917009563	ATP binding site [chemical binding]; other site
1298917009564	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1298917009565	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1298917009566	Class I aldolases; Region: Aldolase_Class_I; cl17187
1298917009567	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
1298917009568	dimerization interface [polypeptide binding]; other site
1298917009569	putative active cleft [active]
1298917009570	alpha-glucosidase; Provisional; Region: PRK10426
1298917009571	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1298917009572	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
1298917009573	putative active site [active]
1298917009574	putative catalytic site [active]
1298917009575	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1298917009576	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917009577	putative substrate translocation pore; other site
1298917009578	outer membrane porin L; Provisional; Region: ompL; PRK09980
1298917009579	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; Region: RimK; COG0189
1298917009580	Sulfatase; Region: Sulfatase; cl17466
1298917009581	coproporphyrinogen III oxidase; Validated; Region: PRK08208
1298917009582	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917009583	FeS/SAM binding site; other site
1298917009584	HemN C-terminal domain; Region: HemN_C; pfam06969
1298917009585	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917009586	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1298917009587	active site
1298917009588	motif I; other site
1298917009589	motif II; other site
1298917009590	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917009591	GTP-binding protein; Provisional; Region: PRK10218
1298917009592	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1298917009593	G1 box; other site
1298917009594	putative GEF interaction site [polypeptide binding]; other site
1298917009595	GTP/Mg2+ binding site [chemical binding]; other site
1298917009596	Switch I region; other site
1298917009597	G2 box; other site
1298917009598	G3 box; other site
1298917009599	Switch II region; other site
1298917009600	G4 box; other site
1298917009601	G5 box; other site
1298917009602	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1298917009603	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1298917009604	glutamine synthetase; Provisional; Region: glnA; PRK09469
1298917009605	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1298917009606	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1298917009607	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1298917009608	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1298917009609	putative active site [active]
1298917009610	heme pocket [chemical binding]; other site
1298917009611	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917009612	dimer interface [polypeptide binding]; other site
1298917009613	phosphorylation site [posttranslational modification]
1298917009614	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917009615	ATP binding site [chemical binding]; other site
1298917009616	Mg2+ binding site [ion binding]; other site
1298917009617	G-X-G motif; other site
1298917009618	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1298917009619	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917009620	active site
1298917009621	phosphorylation site [posttranslational modification]
1298917009622	intermolecular recognition site; other site
1298917009623	dimerization interface [polypeptide binding]; other site
1298917009624	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917009625	Walker A motif; other site
1298917009626	ATP binding site [chemical binding]; other site
1298917009627	Walker B motif; other site
1298917009628	arginine finger; other site
1298917009629	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1298917009630	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1298917009631	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917009632	FeS/SAM binding site; other site
1298917009633	HemN C-terminal domain; Region: HemN_C; pfam06969
1298917009634	Der GTPase activator (YihI); Region: YihI; cl01172
1298917009635	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1298917009636	G1 box; other site
1298917009637	GTP/Mg2+ binding site [chemical binding]; other site
1298917009638	Switch I region; other site
1298917009639	G2 box; other site
1298917009640	G3 box; other site
1298917009641	Switch II region; other site
1298917009642	G4 box; other site
1298917009643	G5 box; other site
1298917009644	DNA polymerase I; Provisional; Region: PRK05755
1298917009645	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1298917009646	active site
1298917009647	metal binding site 1 [ion binding]; metal-binding site
1298917009648	putative 5' ssDNA interaction site; other site
1298917009649	metal binding site 3; metal-binding site
1298917009650	metal binding site 2 [ion binding]; metal-binding site
1298917009651	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1298917009652	putative DNA binding site [nucleotide binding]; other site
1298917009653	putative metal binding site [ion binding]; other site
1298917009654	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1298917009655	active site
1298917009656	catalytic site [active]
1298917009657	substrate binding site [chemical binding]; other site
1298917009658	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1298917009659	active site
1298917009660	DNA binding site [nucleotide binding]
1298917009661	catalytic site [active]
1298917009662	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1298917009663	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1298917009664	putative acyl-acceptor binding pocket; other site
1298917009665	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1298917009666	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1298917009667	catalytic residues [active]
1298917009668	hinge region; other site
1298917009669	alpha helical domain; other site
1298917009670	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1298917009671	serine/threonine protein kinase; Provisional; Region: PRK11768
1298917009672	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1298917009673	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1298917009674	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1298917009675	GTP binding site; other site
1298917009676	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1298917009677	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917009678	DNA-binding site [nucleotide binding]; DNA binding site
1298917009679	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1298917009680	transcriptional repressor RbsR; Provisional; Region: PRK10423
1298917009681	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917009682	DNA binding site [nucleotide binding]
1298917009683	domain linker motif; other site
1298917009684	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1298917009685	dimerization interface [polypeptide binding]; other site
1298917009686	ligand binding site [chemical binding]; other site
1298917009687	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1298917009688	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1298917009689	substrate binding site [chemical binding]; other site
1298917009690	dimer interface [polypeptide binding]; other site
1298917009691	ATP binding site [chemical binding]; other site
1298917009692	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1298917009693	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1298917009694	ligand binding site [chemical binding]; other site
1298917009695	dimerization interface [polypeptide binding]; other site
1298917009696	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1298917009697	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1298917009698	TM-ABC transporter signature motif; other site
1298917009699	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1298917009700	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1298917009701	Walker A/P-loop; other site
1298917009702	ATP binding site [chemical binding]; other site
1298917009703	Q-loop/lid; other site
1298917009704	ABC transporter signature motif; other site
1298917009705	Walker B; other site
1298917009706	D-loop; other site
1298917009707	H-loop/switch region; other site
1298917009708	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1298917009709	D-ribose pyranase; Provisional; Region: PRK11797
1298917009710	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1298917009711	potassium uptake protein; Region: kup; TIGR00794
1298917009712	regulatory ATPase RavA; Provisional; Region: PRK13531
1298917009713	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917009714	Walker A motif; other site
1298917009715	ATP binding site [chemical binding]; other site
1298917009716	Walker B motif; other site
1298917009717	arginine finger; other site
1298917009718	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1298917009719	hypothetical protein; Provisional; Region: yieM; PRK10997
1298917009720	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1298917009721	metal ion-dependent adhesion site (MIDAS); other site
1298917009722	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1298917009723	dimer interface [polypeptide binding]; other site
1298917009724	active site
1298917009725	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1298917009726	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1298917009727	putative DNA binding site [nucleotide binding]; other site
1298917009728	putative Zn2+ binding site [ion binding]; other site
1298917009729	AsnC family; Region: AsnC_trans_reg; pfam01037
1298917009730	FMN-binding protein MioC; Provisional; Region: PRK09004
1298917009731	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1298917009732	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1298917009733	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1298917009734	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1298917009735	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917009736	S-adenosylmethionine binding site [chemical binding]; other site
1298917009737	ATP synthase I chain; Region: ATP_synt_I; cl09170
1298917009738	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1298917009739	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1298917009740	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1298917009741	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1298917009742	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1298917009743	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1298917009744	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1298917009745	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1298917009746	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1298917009747	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1298917009748	beta subunit interaction interface [polypeptide binding]; other site
1298917009749	Walker A motif; other site
1298917009750	ATP binding site [chemical binding]; other site
1298917009751	Walker B motif; other site
1298917009752	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1298917009753	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1298917009754	core domain interface [polypeptide binding]; other site
1298917009755	delta subunit interface [polypeptide binding]; other site
1298917009756	epsilon subunit interface [polypeptide binding]; other site
1298917009757	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1298917009758	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1298917009759	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1298917009760	alpha subunit interaction interface [polypeptide binding]; other site
1298917009761	Walker A motif; other site
1298917009762	ATP binding site [chemical binding]; other site
1298917009763	Walker B motif; other site
1298917009764	inhibitor binding site; inhibition site
1298917009765	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1298917009766	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1298917009767	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1298917009768	gamma subunit interface [polypeptide binding]; other site
1298917009769	epsilon subunit interface [polypeptide binding]; other site
1298917009770	LBP interface [polypeptide binding]; other site
1298917009771	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1298917009772	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
1298917009773	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1298917009774	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1298917009775	Substrate binding site; other site
1298917009776	Mg++ binding site; other site
1298917009777	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1298917009778	active site
1298917009779	substrate binding site [chemical binding]; other site
1298917009780	CoA binding site [chemical binding]; other site
1298917009781	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1298917009782	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1298917009783	glutaminase active site [active]
1298917009784	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1298917009785	dimer interface [polypeptide binding]; other site
1298917009786	active site
1298917009787	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1298917009788	dimer interface [polypeptide binding]; other site
1298917009789	active site
1298917009790	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1298917009791	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1298917009792	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1298917009793	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
1298917009794	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1298917009795	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1298917009796	shikimate binding site; other site
1298917009797	NAD(P) binding site [chemical binding]; other site
1298917009798	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1298917009799	active site
1298917009800	P-loop; other site
1298917009801	phosphorylation site [posttranslational modification]
1298917009802	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1298917009803	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1298917009804	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917009805	substrate binding pocket [chemical binding]; other site
1298917009806	membrane-bound complex binding site; other site
1298917009807	hinge residues; other site
1298917009808	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1298917009809	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917009810	dimer interface [polypeptide binding]; other site
1298917009811	conserved gate region; other site
1298917009812	putative PBP binding loops; other site
1298917009813	ABC-ATPase subunit interface; other site
1298917009814	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1298917009815	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917009816	dimer interface [polypeptide binding]; other site
1298917009817	conserved gate region; other site
1298917009818	putative PBP binding loops; other site
1298917009819	ABC-ATPase subunit interface; other site
1298917009820	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1298917009821	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1298917009822	Walker A/P-loop; other site
1298917009823	ATP binding site [chemical binding]; other site
1298917009824	Q-loop/lid; other site
1298917009825	ABC transporter signature motif; other site
1298917009826	Walker B; other site
1298917009827	D-loop; other site
1298917009828	H-loop/switch region; other site
1298917009829	transcriptional regulator PhoU; Provisional; Region: PRK11115
1298917009830	PhoU domain; Region: PhoU; pfam01895
1298917009831	PhoU domain; Region: PhoU; pfam01895
1298917009832	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1298917009833	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917009834	active site
1298917009835	motif I; other site
1298917009836	motif II; other site
1298917009837	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1298917009838	Predicted flavoprotein [General function prediction only]; Region: COG0431
1298917009839	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1298917009840	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1298917009841	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1298917009842	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917009843	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1298917009844	substrate binding pocket [chemical binding]; other site
1298917009845	dimerization interface [polypeptide binding]; other site
1298917009846	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1298917009847	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917009848	putative substrate translocation pore; other site
1298917009849	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1298917009850	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1298917009851	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1298917009852	G1 box; other site
1298917009853	GTP/Mg2+ binding site [chemical binding]; other site
1298917009854	Switch I region; other site
1298917009855	G2 box; other site
1298917009856	Switch II region; other site
1298917009857	G3 box; other site
1298917009858	G4 box; other site
1298917009859	G5 box; other site
1298917009860	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1298917009861	membrane protein insertase; Provisional; Region: PRK01318
1298917009862	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
1298917009863	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1298917009864	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1298917009865	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1298917009866	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1298917009867	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917009868	Walker A motif; other site
1298917009869	ATP binding site [chemical binding]; other site
1298917009870	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1298917009871	Walker B motif; other site
1298917009872	arginine finger; other site
1298917009873	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1298917009874	DnaA box-binding interface [nucleotide binding]; other site
1298917009875	DNA polymerase III subunit beta; Validated; Region: PRK05643
1298917009876	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1298917009877	putative DNA binding surface [nucleotide binding]; other site
1298917009878	dimer interface [polypeptide binding]; other site
1298917009879	beta-clamp/clamp loader binding surface; other site
1298917009880	beta-clamp/translesion DNA polymerase binding surface; other site
1298917009881	recF protein; Region: recf; TIGR00611
1298917009882	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917009883	Walker A/P-loop; other site
1298917009884	ATP binding site [chemical binding]; other site
1298917009885	Q-loop/lid; other site
1298917009886	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917009887	ABC transporter signature motif; other site
1298917009888	Walker B; other site
1298917009889	D-loop; other site
1298917009890	H-loop/switch region; other site
1298917009891	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1298917009892	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917009893	Mg2+ binding site [ion binding]; other site
1298917009894	G-X-G motif; other site
1298917009895	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1298917009896	anchoring element; other site
1298917009897	dimer interface [polypeptide binding]; other site
1298917009898	ATP binding site [chemical binding]; other site
1298917009899	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1298917009900	active site
1298917009901	putative metal-binding site [ion binding]; other site
1298917009902	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1298917009903	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917009904	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917009905	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1298917009906	putative dimerization interface [polypeptide binding]; other site
1298917009907	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1298917009908	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1298917009909	active site pocket [active]
1298917009910	sugar phosphate phosphatase; Provisional; Region: PRK10513
1298917009911	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917009912	active site
1298917009913	motif I; other site
1298917009914	motif II; other site
1298917009915	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917009916	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1298917009917	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917009918	DNA-binding site [nucleotide binding]; DNA binding site
1298917009919	FCD domain; Region: FCD; pfam07729
1298917009920	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1298917009921	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
1298917009922	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
1298917009923	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1298917009924	active site
1298917009925	intersubunit interface [polypeptide binding]; other site
1298917009926	catalytic residue [active]
1298917009927	galactonate dehydratase; Provisional; Region: PRK14017
1298917009928	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
1298917009929	putative active site pocket [active]
1298917009930	putative metal binding site [ion binding]; other site
1298917009931	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1298917009932	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1298917009933	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1298917009934	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1298917009935	molybdopterin cofactor binding site; other site
1298917009936	chaperone protein TorD; Validated; Region: torD; PRK04976
1298917009937	Haem-binding domain; Region: Haem_bd; pfam14376
1298917009938	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1298917009939	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1298917009940	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917009941	Walker A/P-loop; other site
1298917009942	ATP binding site [chemical binding]; other site
1298917009943	Q-loop/lid; other site
1298917009944	ABC transporter signature motif; other site
1298917009945	Walker B; other site
1298917009946	D-loop; other site
1298917009947	H-loop/switch region; other site
1298917009948	heme exporter protein CcmB; Region: ccmB; TIGR01190
1298917009949	heme exporter protein CcmC; Region: ccmC; TIGR01191
1298917009950	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1298917009951	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1298917009952	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1298917009953	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1298917009954	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1298917009955	catalytic residues [active]
1298917009956	central insert; other site
1298917009957	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1298917009958	hypothetical protein; Provisional; Region: PRK11616
1298917009959	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1298917009960	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1298917009961	putative dimer interface [polypeptide binding]; other site
1298917009962	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1298917009963	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1298917009964	putative dimer interface [polypeptide binding]; other site
1298917009965	putative transporter; Validated; Region: PRK03818
1298917009966	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1298917009967	TrkA-C domain; Region: TrkA_C; pfam02080
1298917009968	TrkA-C domain; Region: TrkA_C; pfam02080
1298917009969	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1298917009970	Predicted membrane protein [Function unknown]; Region: COG2149
1298917009971	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1298917009972	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
1298917009973	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
1298917009974	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1298917009975	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1298917009976	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1298917009977	catalytic residue [active]
1298917009978	permease DsdX; Provisional; Region: PRK09921
1298917009979	gluconate transporter; Region: gntP; TIGR00791
1298917009980	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
1298917009981	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917009982	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1298917009983	dimerization interface [polypeptide binding]; other site
1298917009984	substrate binding pocket [chemical binding]; other site
1298917009985	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1298917009986	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917009987	putative substrate translocation pore; other site
1298917009988	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1298917009989	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1298917009990	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1298917009991	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1298917009992	PYR/PP interface [polypeptide binding]; other site
1298917009993	dimer interface [polypeptide binding]; other site
1298917009994	TPP binding site [chemical binding]; other site
1298917009995	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1298917009996	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1298917009997	TPP-binding site [chemical binding]; other site
1298917009998	dimer interface [polypeptide binding]; other site
1298917009999	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1298917010000	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1298917010001	putative valine binding site [chemical binding]; other site
1298917010002	dimer interface [polypeptide binding]; other site
1298917010003	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1298917010004	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1298917010005	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917010006	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1298917010007	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1298917010008	substrate binding site [chemical binding]; other site
1298917010009	dimer interface [polypeptide binding]; other site
1298917010010	ATP binding site [chemical binding]; other site
1298917010011	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1298917010012	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917010013	putative substrate translocation pore; other site
1298917010014	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
1298917010015	active site
1298917010016	catalytic residues [active]
1298917010017	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1298917010018	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917010019	active site
1298917010020	phosphorylation site [posttranslational modification]
1298917010021	intermolecular recognition site; other site
1298917010022	dimerization interface [polypeptide binding]; other site
1298917010023	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917010024	DNA binding residues [nucleotide binding]
1298917010025	dimerization interface [polypeptide binding]; other site
1298917010026	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1298917010027	MASE1; Region: MASE1; pfam05231
1298917010028	Histidine kinase; Region: HisKA_3; pfam07730
1298917010029	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917010030	ATP binding site [chemical binding]; other site
1298917010031	Mg2+ binding site [ion binding]; other site
1298917010032	G-X-G motif; other site
1298917010033	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1298917010034	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917010035	putative substrate translocation pore; other site
1298917010036	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1298917010037	Predicted transcriptional regulator [Transcription]; Region: COG2944
1298917010038	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917010039	non-specific DNA binding site [nucleotide binding]; other site
1298917010040	salt bridge; other site
1298917010041	sequence-specific DNA binding site [nucleotide binding]; other site
1298917010042	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
1298917010043	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1298917010044	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917010045	putative substrate translocation pore; other site
1298917010046	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1298917010047	beta-galactosidase; Region: BGL; TIGR03356
1298917010048	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1298917010049	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917010050	Walker A motif; other site
1298917010051	ATP binding site [chemical binding]; other site
1298917010052	Walker B motif; other site
1298917010053	arginine finger; other site
1298917010054	Transcriptional antiterminator [Transcription]; Region: COG3933
1298917010055	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1298917010056	active site
1298917010057	active pocket/dimerization site; other site
1298917010058	phosphorylation site [posttranslational modification]
1298917010059	PRD domain; Region: PRD; pfam00874
1298917010060	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1298917010061	active pocket/dimerization site; other site
1298917010062	active site
1298917010063	phosphorylation site [posttranslational modification]
1298917010064	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1298917010065	active site
1298917010066	phosphorylation site [posttranslational modification]
1298917010067	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1298917010068	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1298917010069	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1298917010070	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
1298917010071	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1298917010072	hypothetical protein; Provisional; Region: PRK09956
1298917010073	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1298917010074	EamA-like transporter family; Region: EamA; pfam00892
1298917010075	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1298917010076	EamA-like transporter family; Region: EamA; pfam00892
1298917010077	magnesium transport protein MgtC; Provisional; Region: PRK15385
1298917010078	MgtC family; Region: MgtC; pfam02308
1298917010079	magnesium-transporting ATPase; Provisional; Region: PRK15122
1298917010080	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1298917010081	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1298917010082	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1298917010083	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917010084	motif II; other site
1298917010085	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1298917010086	Isochorismatase family; Region: Isochorismatase; pfam00857
1298917010087	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1298917010088	catalytic triad [active]
1298917010089	dimer interface [polypeptide binding]; other site
1298917010090	conserved cis-peptide bond; other site
1298917010091	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1298917010092	DNA binding site [nucleotide binding]
1298917010093	autotransport protein MisL; Provisional; Region: PRK15313
1298917010094	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1298917010095	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1298917010096	Virulence protein [General function prediction only]; Region: COG3943
1298917010097	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1298917010098	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1298917010099	putative alpha-glucosidase; Provisional; Region: PRK10658
1298917010100	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1298917010101	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1298917010102	active site
1298917010103	homotrimer interface [polypeptide binding]; other site
1298917010104	catalytic site [active]
1298917010105	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1298917010106	AsmA family; Region: AsmA; pfam05170
1298917010107	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
1298917010108	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1298917010109	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1298917010110	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1298917010111	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1298917010112	generic binding surface II; other site
1298917010113	ssDNA binding site; other site
1298917010114	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1298917010115	ATP binding site [chemical binding]; other site
1298917010116	putative Mg++ binding site [ion binding]; other site
1298917010117	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1298917010118	nucleotide binding region [chemical binding]; other site
1298917010119	ATP-binding site [chemical binding]; other site
1298917010120	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1298917010121	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1298917010122	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1298917010123	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1298917010124	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1298917010125	Zn2+ binding site [ion binding]; other site
1298917010126	Mg2+ binding site [ion binding]; other site
1298917010127	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1298917010128	synthetase active site [active]
1298917010129	NTP binding site [chemical binding]; other site
1298917010130	metal binding site [ion binding]; metal-binding site
1298917010131	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1298917010132	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1298917010133	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1298917010134	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1298917010135	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1298917010136	catalytic site [active]
1298917010137	G-X2-G-X-G-K; other site
1298917010138	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1298917010139	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1298917010140	nucleotide binding pocket [chemical binding]; other site
1298917010141	K-X-D-G motif; other site
1298917010142	catalytic site [active]
1298917010143	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1298917010144	Predicted membrane protein [Function unknown]; Region: COG2860
1298917010145	UPF0126 domain; Region: UPF0126; pfam03458
1298917010146	UPF0126 domain; Region: UPF0126; pfam03458
1298917010147	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1298917010148	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917010149	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917010150	dimerization interface [polypeptide binding]; other site
1298917010151	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1298917010152	hypothetical protein; Provisional; Region: PRK11820
1298917010153	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1298917010154	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1298917010155	ribonuclease PH; Reviewed; Region: rph; PRK00173
1298917010156	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1298917010157	hexamer interface [polypeptide binding]; other site
1298917010158	active site
1298917010159	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1298917010160	active site
1298917010161	division inhibitor protein; Provisional; Region: slmA; PRK09480
1298917010162	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917010163	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1298917010164	trimer interface [polypeptide binding]; other site
1298917010165	active site
1298917010166	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1298917010167	Flavoprotein; Region: Flavoprotein; pfam02441
1298917010168	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1298917010169	hypothetical protein; Reviewed; Region: PRK00024
1298917010170	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1298917010171	MPN+ (JAMM) motif; other site
1298917010172	Zinc-binding site [ion binding]; other site
1298917010173	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1298917010174	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1298917010175	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1298917010176	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1298917010177	DNA binding site [nucleotide binding]
1298917010178	catalytic residue [active]
1298917010179	H2TH interface [polypeptide binding]; other site
1298917010180	putative catalytic residues [active]
1298917010181	turnover-facilitating residue; other site
1298917010182	intercalation triad [nucleotide binding]; other site
1298917010183	8OG recognition residue [nucleotide binding]; other site
1298917010184	putative reading head residues; other site
1298917010185	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1298917010186	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1298917010187	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1298917010188	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1298917010189	active site
1298917010190	(T/H)XGH motif; other site
1298917010191	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1298917010192	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1298917010193	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1298917010194	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1298917010195	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1298917010196	putative active site [active]
1298917010197	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1298917010198	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1298917010199	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
1298917010200	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1298917010201	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
1298917010202	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1298917010203	putative ADP-binding pocket [chemical binding]; other site
1298917010204	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1298917010205	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1298917010206	Ligand binding site; other site
1298917010207	metal-binding site
1298917010208	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1298917010209	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1298917010210	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1298917010211	Ligand binding site; other site
1298917010212	metal-binding site
1298917010213	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1298917010214	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
1298917010215	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
1298917010216	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
1298917010217	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1298917010218	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1298917010219	O-antigen ligase RfaL; Provisional; Region: PRK15487
1298917010220	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1298917010221	Glycosyltransferase family 9 (heptosyltransferase); Region: Glyco_transf_9; pfam01075
1298917010222	putative active site [active]
1298917010223	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1298917010224	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1298917010225	putative active site [active]
1298917010226	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1298917010227	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1298917010228	NADP binding site [chemical binding]; other site
1298917010229	homopentamer interface [polypeptide binding]; other site
1298917010230	substrate binding site [chemical binding]; other site
1298917010231	active site
1298917010232	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1298917010233	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1298917010234	substrate-cofactor binding pocket; other site
1298917010235	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917010236	catalytic residue [active]
1298917010237	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1298917010238	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1298917010239	NAD(P) binding site [chemical binding]; other site
1298917010240	putative glycosyl transferase; Provisional; Region: PRK10073
1298917010241	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1298917010242	active site
1298917010243	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1298917010244	NodB motif; other site
1298917010245	putative active site [active]
1298917010246	putative catalytic site [active]
1298917010247	Zn binding site [ion binding]; other site
1298917010248	AmiB activator; Provisional; Region: PRK11637
1298917010249	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1298917010250	Peptidase family M23; Region: Peptidase_M23; pfam01551
1298917010251	phosphoglyceromutase; Provisional; Region: PRK05434
1298917010252	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1298917010253	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1298917010254	active site residue [active]
1298917010255	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1298917010256	GSH binding site [chemical binding]; other site
1298917010257	catalytic residues [active]
1298917010258	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1298917010259	SecA binding site; other site
1298917010260	Preprotein binding site; other site
1298917010261	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1298917010262	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1298917010263	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1298917010264	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1298917010265	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1298917010266	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1298917010267	trimer interface [polypeptide binding]; other site
1298917010268	active site
1298917010269	substrate binding site [chemical binding]; other site
1298917010270	CoA binding site [chemical binding]; other site
1298917010271	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1298917010272	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1298917010273	active site pocket [active]
1298917010274	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1298917010275	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917010276	DNA binding site [nucleotide binding]
1298917010277	domain linker motif; other site
1298917010278	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1298917010279	putative dimerization interface [polypeptide binding]; other site
1298917010280	putative ligand binding site [chemical binding]; other site
1298917010281	putative rRNA methylase; Provisional; Region: PRK10358
1298917010282	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1298917010283	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1298917010284	active site
1298917010285	substrate binding site [chemical binding]; other site
1298917010286	FMN binding site [chemical binding]; other site
1298917010287	putative catalytic residues [active]
1298917010288	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1298917010289	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917010290	DNA-binding site [nucleotide binding]; DNA binding site
1298917010291	FCD domain; Region: FCD; pfam07729
1298917010292	L-lactate permease; Provisional; Region: PRK10420
1298917010293	glycolate transporter; Provisional; Region: PRK09695
1298917010294	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
1298917010295	hypothetical protein; Provisional; Region: PRK11020
1298917010296	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1298917010297	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1298917010298	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1298917010299	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1298917010300	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1298917010301	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1298917010302	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1298917010303	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1298917010304	active site
1298917010305	P-loop; other site
1298917010306	phosphorylation site [posttranslational modification]
1298917010307	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1298917010308	active site
1298917010309	phosphorylation site [posttranslational modification]
1298917010310	putative glutathione S-transferase; Provisional; Region: PRK10357
1298917010311	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1298917010312	putative C-terminal domain interface [polypeptide binding]; other site
1298917010313	putative GSH binding site (G-site) [chemical binding]; other site
1298917010314	putative dimer interface [polypeptide binding]; other site
1298917010315	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1298917010316	dimer interface [polypeptide binding]; other site
1298917010317	N-terminal domain interface [polypeptide binding]; other site
1298917010318	putative substrate binding pocket (H-site) [chemical binding]; other site
1298917010319	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1298917010320	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1298917010321	nucleotide binding site [chemical binding]; other site
1298917010322	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1298917010323	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1298917010324	NAD(P) binding site [chemical binding]; other site
1298917010325	catalytic residues [active]
1298917010326	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1298917010327	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1298917010328	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1298917010329	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1298917010330	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917010331	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1298917010332	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1298917010333	intersubunit interface [polypeptide binding]; other site
1298917010334	active site
1298917010335	Zn2+ binding site [ion binding]; other site
1298917010336	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1298917010337	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1298917010338	AP (apurinic/apyrimidinic) site pocket; other site
1298917010339	DNA interaction; other site
1298917010340	Metal-binding active site; metal-binding site
1298917010341	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1298917010342	active site
1298917010343	dimer interface [polypeptide binding]; other site
1298917010344	magnesium binding site [ion binding]; other site
1298917010345	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1298917010346	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1298917010347	putative N- and C-terminal domain interface [polypeptide binding]; other site
1298917010348	putative active site [active]
1298917010349	MgATP binding site [chemical binding]; other site
1298917010350	catalytic site [active]
1298917010351	metal binding site [ion binding]; metal-binding site
1298917010352	putative xylulose binding site [chemical binding]; other site
1298917010353	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1298917010354	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1298917010355	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
1298917010356	DctM-like transporters; Region: DctM; pfam06808
1298917010357	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
1298917010358	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1298917010359	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1298917010360	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1298917010361	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1298917010362	Bacterial transcriptional regulator; Region: IclR; pfam01614
1298917010363	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1298917010364	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1298917010365	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917010366	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917010367	homodimer interface [polypeptide binding]; other site
1298917010368	catalytic residue [active]
1298917010369	alpha-amylase; Reviewed; Region: malS; PRK09505
1298917010370	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1298917010371	active site
1298917010372	catalytic site [active]
1298917010373	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1298917010374	hypothetical protein; Provisional; Region: PRK10356
1298917010375	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1298917010376	putative dimerization interface [polypeptide binding]; other site
1298917010377	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1298917010378	putative ligand binding site [chemical binding]; other site
1298917010379	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917010380	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1298917010381	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917010382	xylose isomerase; Provisional; Region: PRK05474
1298917010383	xylose isomerase; Region: xylose_isom_A; TIGR02630
1298917010384	Predicted membrane protein [Function unknown]; Region: COG4682
1298917010385	yiaA/B two helix domain; Region: YiaAB; cl01759
1298917010386	yiaA/B two helix domain; Region: YiaAB; cl01759
1298917010387	YsaB-like lipoprotein; Region: YsaB; pfam13983
1298917010388	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1298917010389	dimer interface [polypeptide binding]; other site
1298917010390	motif 1; other site
1298917010391	active site
1298917010392	motif 2; other site
1298917010393	motif 3; other site
1298917010394	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1298917010395	DALR anticodon binding domain; Region: DALR_1; pfam05746
1298917010396	Integrase core domain; Region: rve; pfam00665
1298917010397	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1298917010398	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917010399	Coenzyme A binding pocket [chemical binding]; other site
1298917010400	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1298917010401	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1298917010402	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1298917010403	DNA-binding site [nucleotide binding]; DNA binding site
1298917010404	RNA-binding motif; other site
1298917010405	Predicted transcriptional regulator [Transcription]; Region: COG2944
1298917010406	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917010407	salt bridge; other site
1298917010408	non-specific DNA binding site [nucleotide binding]; other site
1298917010409	sequence-specific DNA binding site [nucleotide binding]; other site
1298917010410	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1298917010411	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1298917010412	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1298917010413	dimerization interface [polypeptide binding]; other site
1298917010414	ligand binding site [chemical binding]; other site
1298917010415	NADP binding site [chemical binding]; other site
1298917010416	catalytic site [active]
1298917010417	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1298917010418	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1298917010419	ligand binding site [chemical binding]; other site
1298917010420	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1298917010421	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1298917010422	molybdopterin cofactor binding site [chemical binding]; other site
1298917010423	substrate binding site [chemical binding]; other site
1298917010424	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1298917010425	molybdopterin cofactor binding site; other site
1298917010426	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917010427	Coenzyme A binding pocket [chemical binding]; other site
1298917010428	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
1298917010429	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1298917010430	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
1298917010431	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
1298917010432	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1298917010433	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1298917010434	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
1298917010435	phosphoethanolamine transferase; Provisional; Region: PRK11560
1298917010436	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1298917010437	Sulfatase; Region: Sulfatase; pfam00884
1298917010438	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1298917010439	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917010440	DNA binding site [nucleotide binding]
1298917010441	domain linker motif; other site
1298917010442	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
1298917010443	putative dimerization interface [polypeptide binding]; other site
1298917010444	putative ligand binding site [chemical binding]; other site
1298917010445	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
1298917010446	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1298917010447	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1298917010448	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1298917010449	peptide binding site [polypeptide binding]; other site
1298917010450	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1298917010451	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917010452	dimer interface [polypeptide binding]; other site
1298917010453	conserved gate region; other site
1298917010454	putative PBP binding loops; other site
1298917010455	ABC-ATPase subunit interface; other site
1298917010456	dipeptide transporter; Provisional; Region: PRK10913
1298917010457	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1298917010458	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917010459	dimer interface [polypeptide binding]; other site
1298917010460	conserved gate region; other site
1298917010461	putative PBP binding loops; other site
1298917010462	ABC-ATPase subunit interface; other site
1298917010463	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1298917010464	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1298917010465	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1298917010466	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1298917010467	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1298917010468	Protein of unknown function (DUF3260); Region: DUF3260; cl11881
1298917010469	Protein of unknown function (DUF3260); Region: DUF3260; cl11881
1298917010470	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
1298917010471	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
1298917010472	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
1298917010473	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1298917010474	cell division protein; Provisional; Region: PRK10037
1298917010475	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1298917010476	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1298917010477	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1298917010478	DXD motif; other site
1298917010479	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1298917010480	PilZ domain; Region: PilZ; pfam07238
1298917010481	cellulose synthase regulator protein; Provisional; Region: PRK11114
1298917010482	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1298917010483	putative diguanylate cyclase; Provisional; Region: PRK13561
1298917010484	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1298917010485	metal binding site [ion binding]; metal-binding site
1298917010486	active site
1298917010487	I-site; other site
1298917010488	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917010489	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1298917010490	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1298917010491	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1298917010492	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1298917010493	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1298917010494	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1298917010495	substrate binding site [chemical binding]; other site
1298917010496	ATP binding site [chemical binding]; other site
1298917010497	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1298917010498	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1298917010499	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917010500	metabolite-proton symporter; Region: 2A0106; TIGR00883
1298917010501	putative substrate translocation pore; other site
1298917010502	inner membrane protein YhjD; Region: TIGR00766
1298917010503	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917010504	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917010505	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1298917010506	putative effector binding pocket; other site
1298917010507	putative dimerization interface [polypeptide binding]; other site
1298917010508	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1298917010509	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917010510	DNA binding residues [nucleotide binding]
1298917010511	dimerization interface [polypeptide binding]; other site
1298917010512	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
1298917010513	catalytic residue [active]
1298917010514	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1298917010515	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917010516	DNA-binding site [nucleotide binding]; DNA binding site
1298917010517	UTRA domain; Region: UTRA; pfam07702
1298917010518	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1298917010519	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1298917010520	putative active site [active]
1298917010521	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1298917010522	dimer interface [polypeptide binding]; other site
1298917010523	active site
1298917010524	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
1298917010525	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1298917010526	substrate binding site [chemical binding]; other site
1298917010527	ATP binding site [chemical binding]; other site
1298917010528	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1298917010529	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1298917010530	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1298917010531	active site
1298917010532	homodimer interface [polypeptide binding]; other site
1298917010533	homotetramer interface [polypeptide binding]; other site
1298917010534	glutathione reductase; Validated; Region: PRK06116
1298917010535	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1298917010536	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917010537	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1298917010538	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1298917010539	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1298917010540	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1298917010541	active site
1298917010542	oligopeptidase A; Provisional; Region: PRK10911
1298917010543	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1298917010544	active site
1298917010545	Zn binding site [ion binding]; other site
1298917010546	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1298917010547	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917010548	putative substrate translocation pore; other site
1298917010549	POT family; Region: PTR2; pfam00854
1298917010550	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1298917010551	Ligand Binding Site [chemical binding]; other site
1298917010552	universal stress protein UspB; Provisional; Region: PRK04960
1298917010553	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1298917010554	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1298917010555	Predicted flavoproteins [General function prediction only]; Region: COG2081
1298917010556	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1298917010557	HlyD family secretion protein; Region: HlyD; pfam00529
1298917010558	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1298917010559	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917010560	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1298917010561	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1298917010562	nickel responsive regulator; Provisional; Region: PRK02967
1298917010563	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1298917010564	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1298917010565	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1298917010566	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1298917010567	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1298917010568	major facilitator superfamily transporter; Provisional; Region: PRK05122
1298917010569	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917010570	putative substrate translocation pore; other site
1298917010571	hypothetical protein; Provisional; Region: PRK11615
1298917010572	hypothetical protein; Provisional; Region: PRK11212
1298917010573	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1298917010574	CPxP  motif; other site
1298917010575	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1298917010576	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1298917010577	dimer interface [polypeptide binding]; other site
1298917010578	ligand binding site [chemical binding]; other site
1298917010579	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917010580	dimerization interface [polypeptide binding]; other site
1298917010581	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1298917010582	dimer interface [polypeptide binding]; other site
1298917010583	putative CheW interface [polypeptide binding]; other site
1298917010584	Predicted membrane protein [Function unknown]; Region: COG3714
1298917010585	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1298917010586	hypothetical protein; Provisional; Region: PRK10910
1298917010587	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1298917010588	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917010589	S-adenosylmethionine binding site [chemical binding]; other site
1298917010590	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1298917010591	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1298917010592	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1298917010593	P loop; other site
1298917010594	GTP binding site [chemical binding]; other site
1298917010595	cell division protein FtsE; Provisional; Region: PRK10908
1298917010596	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917010597	Walker A/P-loop; other site
1298917010598	ATP binding site [chemical binding]; other site
1298917010599	Q-loop/lid; other site
1298917010600	ABC transporter signature motif; other site
1298917010601	Walker B; other site
1298917010602	D-loop; other site
1298917010603	H-loop/switch region; other site
1298917010604	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1298917010605	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1298917010606	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1298917010607	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1298917010608	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1298917010609	DNA binding residues [nucleotide binding]
1298917010610	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1298917010611	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1298917010612	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1298917010613	dimerization interface [polypeptide binding]; other site
1298917010614	ligand binding site [chemical binding]; other site
1298917010615	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1298917010616	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1298917010617	Walker A/P-loop; other site
1298917010618	ATP binding site [chemical binding]; other site
1298917010619	Q-loop/lid; other site
1298917010620	ABC transporter signature motif; other site
1298917010621	Walker B; other site
1298917010622	D-loop; other site
1298917010623	H-loop/switch region; other site
1298917010624	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1298917010625	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1298917010626	Walker A/P-loop; other site
1298917010627	ATP binding site [chemical binding]; other site
1298917010628	Q-loop/lid; other site
1298917010629	ABC transporter signature motif; other site
1298917010630	Walker B; other site
1298917010631	D-loop; other site
1298917010632	H-loop/switch region; other site
1298917010633	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1298917010634	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
1298917010635	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1298917010636	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1298917010637	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1298917010638	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917010639	dimer interface [polypeptide binding]; other site
1298917010640	conserved gate region; other site
1298917010641	putative PBP binding loops; other site
1298917010642	ABC-ATPase subunit interface; other site
1298917010643	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1298917010644	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917010645	dimer interface [polypeptide binding]; other site
1298917010646	conserved gate region; other site
1298917010647	ABC-ATPase subunit interface; other site
1298917010648	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1298917010649	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1298917010650	Walker A/P-loop; other site
1298917010651	ATP binding site [chemical binding]; other site
1298917010652	Q-loop/lid; other site
1298917010653	ABC transporter signature motif; other site
1298917010654	Walker B; other site
1298917010655	D-loop; other site
1298917010656	H-loop/switch region; other site
1298917010657	TOBE domain; Region: TOBE_2; pfam08402
1298917010658	hypothetical protein; Provisional; Region: PRK10350
1298917010659	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1298917010660	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1298917010661	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1298917010662	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1298917010663	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1298917010664	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1298917010665	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1298917010666	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1298917010667	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1298917010668	substrate binding site [chemical binding]; other site
1298917010669	dimer interface [polypeptide binding]; other site
1298917010670	ATP binding site [chemical binding]; other site
1298917010671	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1298917010672	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917010673	Coenzyme A binding pocket [chemical binding]; other site
1298917010674	putative oxidoreductase; Provisional; Region: PRK10206
1298917010675	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1298917010676	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1298917010677	Pirin-related protein [General function prediction only]; Region: COG1741
1298917010678	Pirin; Region: Pirin; pfam02678
1298917010679	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1298917010680	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917010681	DNA binding site [nucleotide binding]
1298917010682	domain linker motif; other site
1298917010683	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1298917010684	putative ligand binding site [chemical binding]; other site
1298917010685	putative dimerization interface [polypeptide binding]; other site
1298917010686	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1298917010687	ATP-binding site [chemical binding]; other site
1298917010688	Gluconate-6-phosphate binding site [chemical binding]; other site
1298917010689	low affinity gluconate transporter; Provisional; Region: PRK10472
1298917010690	gluconate transporter; Region: gntP; TIGR00791
1298917010691	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1298917010692	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1298917010693	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1298917010694	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1298917010695	ligand binding site; other site
1298917010696	oligomer interface; other site
1298917010697	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1298917010698	dimer interface [polypeptide binding]; other site
1298917010699	N-terminal domain interface [polypeptide binding]; other site
1298917010700	sulfate 1 binding site; other site
1298917010701	glycogen synthase; Provisional; Region: glgA; PRK00654
1298917010702	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1298917010703	ADP-binding pocket [chemical binding]; other site
1298917010704	homodimer interface [polypeptide binding]; other site
1298917010705	glycogen phosphorylase; Provisional; Region: PRK14986
1298917010706	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1298917010707	homodimer interface [polypeptide binding]; other site
1298917010708	active site pocket [active]
1298917010709	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1298917010710	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1298917010711	Bacterial transcriptional regulator; Region: IclR; pfam01614
1298917010712	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1298917010713	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1298917010714	inhibitor site; inhibition site
1298917010715	active site
1298917010716	dimer interface [polypeptide binding]; other site
1298917010717	catalytic residue [active]
1298917010718	Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism / Carbohydrate transport and metabolism]; Region: IlvD; COG0129
1298917010719	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917010720	D-galactonate transporter; Region: 2A0114; TIGR00893
1298917010721	putative substrate translocation pore; other site
1298917010722	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1298917010723	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1298917010724	dimer interface [polypeptide binding]; other site
1298917010725	active site
1298917010726	metal binding site [ion binding]; metal-binding site
1298917010727	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
1298917010728	hypothetical protein; Provisional; Region: PRK09781
1298917010729	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1298917010730	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1298917010731	active site residue [active]
1298917010732	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1298917010733	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1298917010734	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1298917010735	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1298917010736	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1298917010737	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917010738	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
1298917010739	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
1298917010740	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917010741	Walker A motif; other site
1298917010742	ATP binding site [chemical binding]; other site
1298917010743	Walker B motif; other site
1298917010744	arginine finger; other site
1298917010745	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1298917010746	hypothetical protein; Reviewed; Region: PRK09588
1298917010747	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
1298917010748	transcriptional regulator MalT; Provisional; Region: PRK04841
1298917010749	AAA ATPase domain; Region: AAA_16; pfam13191
1298917010750	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917010751	DNA binding residues [nucleotide binding]
1298917010752	dimerization interface [polypeptide binding]; other site
1298917010753	maltodextrin phosphorylase; Provisional; Region: PRK14985
1298917010754	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1298917010755	homodimer interface [polypeptide binding]; other site
1298917010756	active site pocket [active]
1298917010757	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1298917010758	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1298917010759	high-affinity gluconate transporter; Provisional; Region: PRK14984
1298917010760	gluconate transporter; Region: gntP; TIGR00791
1298917010761	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1298917010762	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1298917010763	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1298917010764	DNA utilization protein GntX; Provisional; Region: PRK11595
1298917010765	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1298917010766	active site
1298917010767	carboxylesterase BioH; Provisional; Region: PRK10349
1298917010768	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1298917010769	hypothetical protein; Provisional; Region: PRK09956
1298917010770	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1298917010771	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1298917010772	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1298917010773	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1298917010774	G1 box; other site
1298917010775	GTP/Mg2+ binding site [chemical binding]; other site
1298917010776	Switch I region; other site
1298917010777	G2 box; other site
1298917010778	G3 box; other site
1298917010779	Switch II region; other site
1298917010780	G4 box; other site
1298917010781	G5 box; other site
1298917010782	Nucleoside recognition; Region: Gate; pfam07670
1298917010783	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1298917010784	Nucleoside recognition; Region: Gate; pfam07670
1298917010785	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1298917010786	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1298917010787	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1298917010788	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1298917010789	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1298917010790	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917010791	active site
1298917010792	phosphorylation site [posttranslational modification]
1298917010793	intermolecular recognition site; other site
1298917010794	dimerization interface [polypeptide binding]; other site
1298917010795	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917010796	DNA binding site [nucleotide binding]
1298917010797	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1298917010798	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917010799	dimerization interface [polypeptide binding]; other site
1298917010800	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917010801	dimer interface [polypeptide binding]; other site
1298917010802	phosphorylation site [posttranslational modification]
1298917010803	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917010804	ATP binding site [chemical binding]; other site
1298917010805	G-X-G motif; other site
1298917010806	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1298917010807	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1298917010808	active site
1298917010809	substrate-binding site [chemical binding]; other site
1298917010810	metal-binding site [ion binding]
1298917010811	ATP binding site [chemical binding]; other site
1298917010812	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1298917010813	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1298917010814	dimerization interface [polypeptide binding]; other site
1298917010815	domain crossover interface; other site
1298917010816	redox-dependent activation switch; other site
1298917010817	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1298917010818	RNA binding surface [nucleotide binding]; other site
1298917010819	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1298917010820	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917010821	motif II; other site
1298917010822	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1298917010823	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1298917010824	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1298917010825	ADP-ribose binding site [chemical binding]; other site
1298917010826	dimer interface [polypeptide binding]; other site
1298917010827	active site
1298917010828	nudix motif; other site
1298917010829	metal binding site [ion binding]; metal-binding site
1298917010830	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1298917010831	Transglycosylase; Region: Transgly; pfam00912
1298917010832	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1298917010833	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1298917010834	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1298917010835	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
1298917010836	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1298917010837	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1298917010838	shikimate kinase; Reviewed; Region: aroK; PRK00131
1298917010839	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1298917010840	ADP binding site [chemical binding]; other site
1298917010841	magnesium binding site [ion binding]; other site
1298917010842	putative shikimate binding site; other site
1298917010843	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1298917010844	active site
1298917010845	dimer interface [polypeptide binding]; other site
1298917010846	metal binding site [ion binding]; metal-binding site
1298917010847	DNA adenine methylase; Provisional; Region: PRK10904
1298917010848	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1298917010849	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1298917010850	substrate binding site [chemical binding]; other site
1298917010851	hexamer interface [polypeptide binding]; other site
1298917010852	metal binding site [ion binding]; metal-binding site
1298917010853	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1298917010854	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917010855	motif II; other site
1298917010856	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1298917010857	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1298917010858	active site
1298917010859	HIGH motif; other site
1298917010860	dimer interface [polypeptide binding]; other site
1298917010861	KMSKS motif; other site
1298917010862	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1298917010863	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1298917010864	siroheme synthase; Provisional; Region: cysG; PRK10637
1298917010865	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1298917010866	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1298917010867	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1298917010868	active site
1298917010869	SAM binding site [chemical binding]; other site
1298917010870	homodimer interface [polypeptide binding]; other site
1298917010871	nitrite transporter NirC; Provisional; Region: PRK11562
1298917010872	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1298917010873	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1298917010874	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1298917010875	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1298917010876	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1298917010877	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1298917010878	putative transporter; Provisional; Region: PRK03699
1298917010879	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917010880	putative substrate translocation pore; other site
1298917010881	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1298917010882	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1298917010883	substrate binding site [chemical binding]; other site
1298917010884	hypothetical protein; Provisional; Region: PRK10204
1298917010885	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1298917010886	cell filamentation protein Fic; Provisional; Region: PRK10347
1298917010887	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1298917010888	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1298917010889	glutamine binding [chemical binding]; other site
1298917010890	catalytic triad [active]
1298917010891	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1298917010892	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1298917010893	inhibitor-cofactor binding pocket; inhibition site
1298917010894	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917010895	catalytic residue [active]
1298917010896	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1298917010897	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1298917010898	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1298917010899	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1298917010900	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1298917010901	ligand binding site [chemical binding]; other site
1298917010902	flexible hinge region; other site
1298917010903	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1298917010904	putative switch regulator; other site
1298917010905	non-specific DNA interactions [nucleotide binding]; other site
1298917010906	DNA binding site [nucleotide binding]
1298917010907	sequence specific DNA binding site [nucleotide binding]; other site
1298917010908	putative cAMP binding site [chemical binding]; other site
1298917010909	hypothetical protein; Provisional; Region: PRK10738
1298917010910	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1298917010911	active site
1298917010912	hypothetical protein; Provisional; Region: PRK04966
1298917010913	putative hydrolase; Provisional; Region: PRK10985
1298917010914	putative monooxygenase; Provisional; Region: PRK11118
1298917010915	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1298917010916	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917010917	Walker A/P-loop; other site
1298917010918	ATP binding site [chemical binding]; other site
1298917010919	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1298917010920	ABC transporter signature motif; other site
1298917010921	Walker B; other site
1298917010922	D-loop; other site
1298917010923	ABC transporter; Region: ABC_tran_2; pfam12848
1298917010924	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1298917010925	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1298917010926	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1298917010927	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1298917010928	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1298917010929	phi X174 lysis protein; Provisional; Region: PRK02793
1298917010930	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1298917010931	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1298917010932	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1298917010933	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1298917010934	sulfur relay protein TusC; Validated; Region: PRK00211
1298917010935	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1298917010936	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1298917010937	S17 interaction site [polypeptide binding]; other site
1298917010938	S8 interaction site; other site
1298917010939	16S rRNA interaction site [nucleotide binding]; other site
1298917010940	streptomycin interaction site [chemical binding]; other site
1298917010941	23S rRNA interaction site [nucleotide binding]; other site
1298917010942	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1298917010943	30S ribosomal protein S7; Validated; Region: PRK05302
1298917010944	elongation factor G; Reviewed; Region: PRK00007
1298917010945	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1298917010946	G1 box; other site
1298917010947	putative GEF interaction site [polypeptide binding]; other site
1298917010948	GTP/Mg2+ binding site [chemical binding]; other site
1298917010949	Switch I region; other site
1298917010950	G2 box; other site
1298917010951	G3 box; other site
1298917010952	Switch II region; other site
1298917010953	G4 box; other site
1298917010954	G5 box; other site
1298917010955	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1298917010956	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1298917010957	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1298917010958	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1298917010959	Switch II region; other site
1298917010960	G4 box; other site
1298917010961	G5 box; other site
1298917010962	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1298917010963	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1298917010964	Antibiotic Binding Site [chemical binding]; other site
1298917010965	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1298917010966	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1298917010967	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1298917010968	heme binding site [chemical binding]; other site
1298917010969	ferroxidase pore; other site
1298917010970	ferroxidase diiron center [ion binding]; other site
1298917010971	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1298917010972	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1298917010973	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1298917010974	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1298917010975	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1298917010976	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1298917010977	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1298917010978	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1298917010979	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1298917010980	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1298917010981	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1298917010982	protein-rRNA interface [nucleotide binding]; other site
1298917010983	putative translocon binding site; other site
1298917010984	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1298917010985	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1298917010986	G-X-X-G motif; other site
1298917010987	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1298917010988	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1298917010989	23S rRNA interface [nucleotide binding]; other site
1298917010990	5S rRNA interface [nucleotide binding]; other site
1298917010991	putative antibiotic binding site [chemical binding]; other site
1298917010992	L25 interface [polypeptide binding]; other site
1298917010993	L27 interface [polypeptide binding]; other site
1298917010994	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1298917010995	23S rRNA interface [nucleotide binding]; other site
1298917010996	putative translocon interaction site; other site
1298917010997	signal recognition particle (SRP54) interaction site; other site
1298917010998	L23 interface [polypeptide binding]; other site
1298917010999	trigger factor interaction site; other site
1298917011000	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1298917011001	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1298917011002	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1298917011003	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1298917011004	RNA binding site [nucleotide binding]; other site
1298917011005	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1298917011006	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1298917011007	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1298917011008	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1298917011009	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1298917011010	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1298917011011	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1298917011012	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1298917011013	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1298917011014	23S rRNA interface [nucleotide binding]; other site
1298917011015	5S rRNA interface [nucleotide binding]; other site
1298917011016	L27 interface [polypeptide binding]; other site
1298917011017	L5 interface [polypeptide binding]; other site
1298917011018	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1298917011019	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1298917011020	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1298917011021	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1298917011022	23S rRNA binding site [nucleotide binding]; other site
1298917011023	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1298917011024	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1298917011025	SecY translocase; Region: SecY; pfam00344
1298917011026	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1298917011027	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1298917011028	30S ribosomal protein S11; Validated; Region: PRK05309
1298917011029	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1298917011030	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1298917011031	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1298917011032	RNA binding surface [nucleotide binding]; other site
1298917011033	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1298917011034	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1298917011035	alphaNTD homodimer interface [polypeptide binding]; other site
1298917011036	alphaNTD - beta interaction site [polypeptide binding]; other site
1298917011037	alphaNTD - beta' interaction site [polypeptide binding]; other site
1298917011038	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1298917011039	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1298917011040	hypothetical protein; Provisional; Region: PRK10203
1298917011041	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1298917011042	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1298917011043	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1298917011044	TrkA-N domain; Region: TrkA_N; pfam02254
1298917011045	TrkA-C domain; Region: TrkA_C; pfam02080
1298917011046	TrkA-N domain; Region: TrkA_N; pfam02254
1298917011047	TrkA-C domain; Region: TrkA_C; pfam02080
1298917011048	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1298917011049	putative RNA binding site [nucleotide binding]; other site
1298917011050	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1298917011051	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917011052	S-adenosylmethionine binding site [chemical binding]; other site
1298917011053	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1298917011054	active site
1298917011055	catalytic residues [active]
1298917011056	metal binding site [ion binding]; metal-binding site
1298917011057	hypothetical protein; Validated; Region: PRK03430
1298917011058	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1298917011059	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1298917011060	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1298917011061	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1298917011062	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1298917011063	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1298917011064	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1298917011065	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1298917011066	shikimate binding site; other site
1298917011067	NAD(P) binding site [chemical binding]; other site
1298917011068	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1298917011069	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1298917011070	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1298917011071	trimer interface [polypeptide binding]; other site
1298917011072	putative metal binding site [ion binding]; other site
1298917011073	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1298917011074	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917011075	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1298917011076	Coenzyme A binding pocket [chemical binding]; other site
1298917011077	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1298917011078	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1298917011079	proposed active site lysine [active]
1298917011080	conserved cys residue [active]
1298917011081	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1298917011082	malate synthase A; Region: malate_syn_A; TIGR01344
1298917011083	active site
1298917011084	isocitrate lyase; Provisional; Region: PRK15063
1298917011085	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1298917011086	tetramer interface [polypeptide binding]; other site
1298917011087	active site
1298917011088	Mg2+/Mn2+ binding site [ion binding]; other site
1298917011089	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1298917011090	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1298917011091	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1298917011092	transcriptional repressor IclR; Provisional; Region: PRK11569
1298917011093	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1298917011094	Bacterial transcriptional regulator; Region: IclR; pfam01614
1298917011095	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1298917011096	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1298917011097	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1298917011098	substrate binding pocket [chemical binding]; other site
1298917011099	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1298917011100	B12 binding site [chemical binding]; other site
1298917011101	cobalt ligand [ion binding]; other site
1298917011102	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1298917011103	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1298917011104	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1298917011105	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1298917011106	active site pocket [active]
1298917011107	oxyanion hole [active]
1298917011108	catalytic triad [active]
1298917011109	active site nucleophile [active]
1298917011110	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1298917011111	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1298917011112	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1298917011113	RNA binding surface [nucleotide binding]; other site
1298917011114	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1298917011115	probable active site [active]
1298917011116	hypothetical protein; Provisional; Region: PRK10515
1298917011117	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1298917011118	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1298917011119	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917011120	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1298917011121	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917011122	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1298917011123	phosphate binding site [ion binding]; other site
1298917011124	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1298917011125	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1298917011126	trimer interface [polypeptide binding]; other site
1298917011127	active site
1298917011128	substrate binding site [chemical binding]; other site
1298917011129	CoA binding site [chemical binding]; other site
1298917011130	Mor transcription activator family; Region: Mor; pfam08765
1298917011131	aspartate kinase III; Validated; Region: PRK09084
1298917011132	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1298917011133	nucleotide binding site [chemical binding]; other site
1298917011134	substrate binding site [chemical binding]; other site
1298917011135	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1298917011136	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1298917011137	dimer interface [polypeptide binding]; other site
1298917011138	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1298917011139	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1298917011140	active site
1298917011141	dimer interface [polypeptide binding]; other site
1298917011142	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1298917011143	dimer interface [polypeptide binding]; other site
1298917011144	active site
1298917011145	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1298917011146	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1298917011147	Predicted membrane protein [Function unknown]; Region: COG3223
1298917011148	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1298917011149	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917011150	dimer interface [polypeptide binding]; other site
1298917011151	conserved gate region; other site
1298917011152	putative PBP binding loops; other site
1298917011153	ABC-ATPase subunit interface; other site
1298917011154	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1298917011155	dimer interface [polypeptide binding]; other site
1298917011156	conserved gate region; other site
1298917011157	putative PBP binding loops; other site
1298917011158	ABC-ATPase subunit interface; other site
1298917011159	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1298917011160	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1298917011161	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1298917011162	trimer interface; other site
1298917011163	sugar binding site [chemical binding]; other site
1298917011164	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1298917011165	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1298917011166	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1298917011167	UbiA prenyltransferase family; Region: UbiA; pfam01040
1298917011168	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1298917011169	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1298917011170	putative acyl-acceptor binding pocket; other site
1298917011171	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1298917011172	LexA repressor; Validated; Region: PRK00215
1298917011173	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1298917011174	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1298917011175	Catalytic site [active]
1298917011176	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1298917011177	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1298917011178	hypothetical protein; Provisional; Region: PRK10428
1298917011179	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1298917011180	metal binding site 2 [ion binding]; metal-binding site
1298917011181	putative DNA binding helix; other site
1298917011182	metal binding site 1 [ion binding]; metal-binding site
1298917011183	dimer interface [polypeptide binding]; other site
1298917011184	structural Zn2+ binding site [ion binding]; other site
1298917011185	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1298917011186	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1298917011187	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1298917011188	FMN binding site [chemical binding]; other site
1298917011189	active site
1298917011190	catalytic residues [active]
1298917011191	substrate binding site [chemical binding]; other site
1298917011192	phage shock protein G; Reviewed; Region: pspG; PRK09459
1298917011193	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1298917011194	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1298917011195	NADP binding site [chemical binding]; other site
1298917011196	dimer interface [polypeptide binding]; other site
1298917011197	replicative DNA helicase; Provisional; Region: PRK08006
1298917011198	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1298917011199	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1298917011200	Walker A motif; other site
1298917011201	ATP binding site [chemical binding]; other site
1298917011202	Walker B motif; other site
1298917011203	DNA binding loops [nucleotide binding]
1298917011204	alanine racemase; Reviewed; Region: alr; PRK00053
1298917011205	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1298917011206	active site
1298917011207	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1298917011208	substrate binding site [chemical binding]; other site
1298917011209	catalytic residues [active]
1298917011210	dimer interface [polypeptide binding]; other site
1298917011211	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1298917011212	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1298917011213	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917011214	homodimer interface [polypeptide binding]; other site
1298917011215	catalytic residue [active]
1298917011216	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917011217	active site
1298917011218	motif I; other site
1298917011219	motif II; other site
1298917011220	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
1298917011221	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1298917011222	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1298917011223	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1298917011224	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1298917011225	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1298917011226	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1298917011227	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1298917011228	dimer interface [polypeptide binding]; other site
1298917011229	ssDNA binding site [nucleotide binding]; other site
1298917011230	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1298917011231	hypothetical protein; Validated; Region: PRK09039
1298917011232	Outer membrane efflux protein; Region: OEP; pfam02321
1298917011233	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1298917011234	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1298917011235	HlyD family secretion protein; Region: HlyD_3; pfam13437
1298917011236	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011237	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1298917011238	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011239	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011240	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011241	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1298917011242	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1298917011243	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011244	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1298917011245	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011246	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1298917011247	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1298917011248	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011249	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1298917011250	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1298917011251	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011252	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1298917011253	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011254	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011255	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1298917011256	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011257	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011258	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011259	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011260	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011261	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011262	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011263	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011264	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011265	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011266	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
1298917011267	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011268	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1298917011269	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011270	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1298917011271	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1298917011272	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1298917011273	Walker A/P-loop; other site
1298917011274	ATP binding site [chemical binding]; other site
1298917011275	Q-loop/lid; other site
1298917011276	ABC transporter signature motif; other site
1298917011277	Walker B; other site
1298917011278	D-loop; other site
1298917011279	H-loop/switch region; other site
1298917011280	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1298917011281	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1298917011282	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1298917011283	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1298917011284	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917011285	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1298917011286	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1298917011287	DNA binding residues [nucleotide binding]
1298917011288	dimer interface [polypeptide binding]; other site
1298917011289	[2Fe-2S] cluster binding site [ion binding]; other site
1298917011290	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1298917011291	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1298917011292	putative C-terminal domain interface [polypeptide binding]; other site
1298917011293	putative GSH binding site (G-site) [chemical binding]; other site
1298917011294	putative dimer interface [polypeptide binding]; other site
1298917011295	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
1298917011296	putative N-terminal domain interface [polypeptide binding]; other site
1298917011297	putative dimer interface [polypeptide binding]; other site
1298917011298	putative substrate binding pocket (H-site) [chemical binding]; other site
1298917011299	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1298917011300	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1298917011301	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1298917011302	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1298917011303	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1298917011304	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1298917011305	putative dimerization interface [polypeptide binding]; other site
1298917011306	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1298917011307	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1298917011308	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1298917011309	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1298917011310	Na binding site [ion binding]; other site
1298917011311	Predicted membrane protein [Function unknown]; Region: COG3162
1298917011312	acetyl-CoA synthetase; Provisional; Region: PRK00174
1298917011313	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1298917011314	active site
1298917011315	CoA binding site [chemical binding]; other site
1298917011316	acyl-activating enzyme (AAE) consensus motif; other site
1298917011317	AMP binding site [chemical binding]; other site
1298917011318	acetate binding site [chemical binding]; other site
1298917011319	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1298917011320	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
1298917011321	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1298917011322	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
1298917011323	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1298917011324	heme lyase subunit NrfE; Provisional; Region: PRK10369
1298917011325	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
1298917011326	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1298917011327	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1298917011328	binding surface
1298917011329	TPR motif; other site
1298917011330	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1298917011331	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1298917011332	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1298917011333	Sel1-like repeats; Region: SEL1; smart00671
1298917011334	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1298917011335	molybdopterin cofactor binding site; other site
1298917011336	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1298917011337	molybdopterin cofactor binding site; other site
1298917011338	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1298917011339	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
1298917011340	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917011341	Coenzyme A binding pocket [chemical binding]; other site
1298917011342	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1298917011343	dimer interface [polypeptide binding]; other site
1298917011344	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1298917011345	hypothetical protein; Provisional; Region: PRK10220
1298917011346	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1298917011347	PhnA protein; Region: PhnA; pfam03831
1298917011348	proline/glycine betaine transporter; Provisional; Region: PRK10642
1298917011349	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917011350	putative substrate translocation pore; other site
1298917011351	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1298917011352	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1298917011353	HAMP domain; Region: HAMP; pfam00672
1298917011354	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917011355	dimer interface [polypeptide binding]; other site
1298917011356	phosphorylation site [posttranslational modification]
1298917011357	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917011358	ATP binding site [chemical binding]; other site
1298917011359	Mg2+ binding site [ion binding]; other site
1298917011360	G-X-G motif; other site
1298917011361	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1298917011362	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917011363	active site
1298917011364	phosphorylation site [posttranslational modification]
1298917011365	intermolecular recognition site; other site
1298917011366	dimerization interface [polypeptide binding]; other site
1298917011367	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917011368	DNA binding site [nucleotide binding]
1298917011369	putative metal dependent hydrolase; Provisional; Region: PRK11598
1298917011370	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1298917011371	Sulfatase; Region: Sulfatase; pfam00884
1298917011372	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
1298917011373	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917011374	arginine decarboxylase; Provisional; Region: PRK15029
1298917011375	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1298917011376	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1298917011377	homodimer interface [polypeptide binding]; other site
1298917011378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1298917011379	catalytic residue [active]
1298917011380	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1298917011381	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
1298917011382	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917011383	alpha-galactosidase; Provisional; Region: PRK15076
1298917011384	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1298917011385	NAD binding site [chemical binding]; other site
1298917011386	sugar binding site [chemical binding]; other site
1298917011387	divalent metal binding site [ion binding]; other site
1298917011388	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1298917011389	dimer interface [polypeptide binding]; other site
1298917011390	fumarate hydratase; Provisional; Region: PRK15389
1298917011391	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1298917011392	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1298917011393	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1298917011394	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1298917011395	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1298917011396	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917011397	active site
1298917011398	phosphorylation site [posttranslational modification]
1298917011399	intermolecular recognition site; other site
1298917011400	dimerization interface [polypeptide binding]; other site
1298917011401	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1298917011402	PAS domain; Region: PAS; smart00091
1298917011403	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917011404	ATP binding site [chemical binding]; other site
1298917011405	Mg2+ binding site [ion binding]; other site
1298917011406	G-X-G motif; other site
1298917011407	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1298917011408	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1298917011409	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1298917011410	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
1298917011411	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1298917011412	SdiA-regulated; Region: SdiA-regulated; cd09971
1298917011413	putative active site [active]
1298917011414	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1298917011415	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917011416	DNA binding residues [nucleotide binding]
1298917011417	dimerization interface [polypeptide binding]; other site
1298917011418	AraC family transcriptional regulator; Provisional; Region: PRK15186
1298917011419	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917011420	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1298917011421	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917011422	Coenzyme A binding pocket [chemical binding]; other site
1298917011423	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1298917011424	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1298917011425	active site
1298917011426	putative transcriptional regulator; Provisional; Region: PRK11640
1298917011427	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1298917011428	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1298917011429	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1298917011430	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1298917011431	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1298917011432	DsbD alpha interface [polypeptide binding]; other site
1298917011433	catalytic residues [active]
1298917011434	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1298917011435	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1298917011436	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1298917011437	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1298917011438	Aspartase; Region: Aspartase; cd01357
1298917011439	active sites [active]
1298917011440	tetramer interface [polypeptide binding]; other site
1298917011441	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1298917011442	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1298917011443	oligomerisation interface [polypeptide binding]; other site
1298917011444	mobile loop; other site
1298917011445	roof hairpin; other site
1298917011446	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1298917011447	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1298917011448	ring oligomerisation interface [polypeptide binding]; other site
1298917011449	ATP/Mg binding site [chemical binding]; other site
1298917011450	stacking interactions; other site
1298917011451	hinge regions; other site
1298917011452	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1298917011453	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1298917011454	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917011455	FeS/SAM binding site; other site
1298917011456	elongation factor P; Validated; Region: PRK00529
1298917011457	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1298917011458	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1298917011459	RNA binding site [nucleotide binding]; other site
1298917011460	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1298917011461	RNA binding site [nucleotide binding]; other site
1298917011462	Predicted small secreted protein [Function unknown]; Region: COG5510
1298917011463	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
1298917011464	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1298917011465	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917011466	DNA binding residues [nucleotide binding]
1298917011467	dimerization interface [polypeptide binding]; other site
1298917011468	multidrug efflux system protein; Provisional; Region: PRK11431
1298917011469	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1298917011470	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1298917011471	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1298917011472	Iron-sulfur protein interface; other site
1298917011473	proximal quinone binding site [chemical binding]; other site
1298917011474	C-subunit interface; other site
1298917011475	distal quinone binding site; other site
1298917011476	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1298917011477	D-subunit interface [polypeptide binding]; other site
1298917011478	Iron-sulfur protein interface; other site
1298917011479	proximal quinone binding site [chemical binding]; other site
1298917011480	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1298917011481	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1298917011482	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1298917011483	L-aspartate oxidase; Provisional; Region: PRK06175
1298917011484	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1298917011485	poxB regulator PoxA; Provisional; Region: PRK09350
1298917011486	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1298917011487	motif 1; other site
1298917011488	dimer interface [polypeptide binding]; other site
1298917011489	active site
1298917011490	motif 2; other site
1298917011491	motif 3; other site
1298917011492	inner membrane transporter YjeM; Provisional; Region: PRK15238
1298917011493	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
1298917011494	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1298917011495	GTPase RsgA; Reviewed; Region: PRK12288
1298917011496	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1298917011497	RNA binding site [nucleotide binding]; other site
1298917011498	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1298917011499	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1298917011500	GTP/Mg2+ binding site [chemical binding]; other site
1298917011501	G4 box; other site
1298917011502	G5 box; other site
1298917011503	G1 box; other site
1298917011504	Switch I region; other site
1298917011505	G2 box; other site
1298917011506	G3 box; other site
1298917011507	Switch II region; other site
1298917011508	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1298917011509	catalytic site [active]
1298917011510	putative active site [active]
1298917011511	putative substrate binding site [chemical binding]; other site
1298917011512	dimer interface [polypeptide binding]; other site
1298917011513	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1298917011514	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1298917011515	substrate binding pocket [chemical binding]; other site
1298917011516	membrane-bound complex binding site; other site
1298917011517	hinge residues; other site
1298917011518	epoxyqueuosine reductase; Region: TIGR00276
1298917011519	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1298917011520	putative carbohydrate kinase; Provisional; Region: PRK10565
1298917011521	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1298917011522	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1298917011523	putative substrate binding site [chemical binding]; other site
1298917011524	putative ATP binding site [chemical binding]; other site
1298917011525	ADP-binding protein; Provisional; Region: PRK10646
1298917011526	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1298917011527	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1298917011528	active site
1298917011529	metal binding site [ion binding]; metal-binding site
1298917011530	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1298917011531	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917011532	ATP binding site [chemical binding]; other site
1298917011533	Mg2+ binding site [ion binding]; other site
1298917011534	G-X-G motif; other site
1298917011535	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1298917011536	ATP binding site [chemical binding]; other site
1298917011537	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1298917011538	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1298917011539	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1298917011540	bacterial Hfq-like; Region: Hfq; cd01716
1298917011541	hexamer interface [polypeptide binding]; other site
1298917011542	Sm1 motif; other site
1298917011543	RNA binding site [nucleotide binding]; other site
1298917011544	Sm2 motif; other site
1298917011545	GTPase HflX; Provisional; Region: PRK11058
1298917011546	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1298917011547	HflX GTPase family; Region: HflX; cd01878
1298917011548	G1 box; other site
1298917011549	GTP/Mg2+ binding site [chemical binding]; other site
1298917011550	Switch I region; other site
1298917011551	G2 box; other site
1298917011552	G3 box; other site
1298917011553	Switch II region; other site
1298917011554	G4 box; other site
1298917011555	G5 box; other site
1298917011556	FtsH protease regulator HflK; Provisional; Region: PRK10930
1298917011557	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1298917011558	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1298917011559	FtsH protease regulator HflC; Provisional; Region: PRK11029
1298917011560	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1298917011561	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1298917011562	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1298917011563	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1298917011564	GDP-binding site [chemical binding]; other site
1298917011565	ACT binding site; other site
1298917011566	IMP binding site; other site
1298917011567	Predicted transcriptional regulator [Transcription]; Region: COG1959
1298917011568	transcriptional repressor NsrR; Provisional; Region: PRK11014
1298917011569	exoribonuclease R; Provisional; Region: PRK11642
1298917011570	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1298917011571	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1298917011572	RNB domain; Region: RNB; pfam00773
1298917011573	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1298917011574	RNA binding site [nucleotide binding]; other site
1298917011575	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1298917011576	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1298917011577	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1298917011578	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
1298917011579	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1298917011580	Ion channel; Region: Ion_trans_2; pfam07885
1298917011581	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
1298917011582	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
1298917011583	Predicted membrane protein [Function unknown]; Region: COG3766
1298917011584	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1298917011585	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1298917011586	Predicted integral membrane protein [Function unknown]; Region: COG5463
1298917011587	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1298917011588	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1298917011589	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1298917011590	FAD binding site [chemical binding]; other site
1298917011591	substrate binding site [chemical binding]; other site
1298917011592	catalytic residues [active]
1298917011593	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1298917011594	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1298917011595	esterase; Provisional; Region: PRK10566
1298917011596	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1298917011597	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1298917011598	transcriptional repressor UlaR; Provisional; Region: PRK13509
1298917011599	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1298917011600	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1298917011601	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1298917011602	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1298917011603	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1298917011604	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1298917011605	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1298917011606	active site
1298917011607	P-loop; other site
1298917011608	phosphorylation site [posttranslational modification]
1298917011609	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1298917011610	active site
1298917011611	phosphorylation site [posttranslational modification]
1298917011612	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1298917011613	active site
1298917011614	dimer interface [polypeptide binding]; other site
1298917011615	magnesium binding site [ion binding]; other site
1298917011616	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1298917011617	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1298917011618	intersubunit interface [polypeptide binding]; other site
1298917011619	active site
1298917011620	Zn2+ binding site [ion binding]; other site
1298917011621	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1298917011622	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1298917011623	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1298917011624	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1298917011625	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1298917011626	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1298917011627	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1298917011628	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1298917011629	EamA-like transporter family; Region: EamA; pfam00892
1298917011630	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1298917011631	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1298917011632	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1298917011633	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1298917011634	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1298917011635	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1298917011636	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1298917011637	DKNYY family; Region: DKNYY; pfam13644
1298917011638	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1298917011639	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1298917011640	Hemerythrin-like domain; Region: Hr-like; cd12108
1298917011641	Fe binding site [ion binding]; other site
1298917011642	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1298917011643	EamA-like transporter family; Region: EamA; pfam00892
1298917011644	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1298917011645	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1298917011646	NADP binding site [chemical binding]; other site
1298917011647	Predicted transcriptional regulators [Transcription]; Region: COG1733
1298917011648	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1298917011649	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1298917011650	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1298917011651	active site
1298917011652	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
1298917011653	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1298917011654	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1298917011655	Domain of unknown function DUF21; Region: DUF21; pfam01595
1298917011656	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1298917011657	Transporter associated domain; Region: CorC_HlyC; smart01091
1298917011658	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1298917011659	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1298917011660	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1298917011661	Surface antigen; Region: Bac_surface_Ag; pfam01103
1298917011662	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1298917011663	Family of unknown function (DUF490); Region: DUF490; pfam04357
1298917011664	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1298917011665	putative active site pocket [active]
1298917011666	dimerization interface [polypeptide binding]; other site
1298917011667	putative catalytic residue [active]
1298917011668	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917011669	D-galactonate transporter; Region: 2A0114; TIGR00893
1298917011670	putative substrate translocation pore; other site
1298917011671	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
1298917011672	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1298917011673	active site
1298917011674	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1298917011675	dimer interface [polypeptide binding]; other site
1298917011676	substrate binding site [chemical binding]; other site
1298917011677	metal binding sites [ion binding]; metal-binding site
1298917011678	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1298917011679	AMP binding site [chemical binding]; other site
1298917011680	metal binding site [ion binding]; metal-binding site
1298917011681	active site
1298917011682	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1298917011683	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1298917011684	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1298917011685	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1298917011686	hypothetical protein; Provisional; Region: PRK05255
1298917011687	peptidase PmbA; Provisional; Region: PRK11040
1298917011688	cytochrome b562; Provisional; Region: PRK15058
1298917011689	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1298917011690	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
1298917011691	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
1298917011692	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1298917011693	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
1298917011694	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1298917011695	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1298917011696	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1298917011697	HTH domain; Region: HTH_11; pfam08279
1298917011698	Mga helix-turn-helix domain; Region: Mga; pfam05043
1298917011699	PRD domain; Region: PRD; pfam00874
1298917011700	PRD domain; Region: PRD; pfam00874
1298917011701	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1298917011702	active site
1298917011703	P-loop; other site
1298917011704	phosphorylation site [posttranslational modification]
1298917011705	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1298917011706	active site
1298917011707	phosphorylation site [posttranslational modification]
1298917011708	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
1298917011709	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1298917011710	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1298917011711	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917011712	FeS/SAM binding site; other site
1298917011713	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1298917011714	ATP cone domain; Region: ATP-cone; pfam03477
1298917011715	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1298917011716	effector binding site; other site
1298917011717	active site
1298917011718	Zn binding site [ion binding]; other site
1298917011719	glycine loop; other site
1298917011720	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1298917011721	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1298917011722	active site turn [active]
1298917011723	phosphorylation site [posttranslational modification]
1298917011724	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1298917011725	trehalose repressor; Provisional; Region: treR; PRK09492
1298917011726	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917011727	DNA binding site [nucleotide binding]
1298917011728	domain linker motif; other site
1298917011729	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1298917011730	dimerization interface [polypeptide binding]; other site
1298917011731	ligand binding site [chemical binding]; other site
1298917011732	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1298917011733	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1298917011734	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1298917011735	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1298917011736	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1298917011737	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1298917011738	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1298917011739	Transposase; Region: HTH_Tnp_1; cl17663
1298917011740	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1298917011741	homotrimer interaction site [polypeptide binding]; other site
1298917011742	putative active site [active]
1298917011743	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1298917011744	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1298917011745	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1298917011746	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1298917011747	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1298917011748	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1298917011749	Arginine repressor [Transcription]; Region: ArgR; COG1438
1298917011750	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1298917011751	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1298917011752	Predicted membrane protein [Function unknown]; Region: COG1288
1298917011753	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1298917011754	ornithine carbamoyltransferase; Validated; Region: PRK02102
1298917011755	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1298917011756	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1298917011757	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1298917011758	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1298917011759	putative substrate binding site [chemical binding]; other site
1298917011760	nucleotide binding site [chemical binding]; other site
1298917011761	nucleotide binding site [chemical binding]; other site
1298917011762	homodimer interface [polypeptide binding]; other site
1298917011763	arginine deiminase; Provisional; Region: PRK01388
1298917011764	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1298917011765	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1298917011766	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1298917011767	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1298917011768	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
1298917011769	RNase E inhibitor protein; Provisional; Region: PRK11191
1298917011770	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1298917011771	active site
1298917011772	dinuclear metal binding site [ion binding]; other site
1298917011773	dimerization interface [polypeptide binding]; other site
1298917011774	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
1298917011775	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1298917011776	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917011777	Coenzyme A binding pocket [chemical binding]; other site
1298917011778	Predicted membrane protein [Function unknown]; Region: COG4269
1298917011779	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1298917011780	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1298917011781	HIGH motif; other site
1298917011782	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1298917011783	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1298917011784	active site
1298917011785	KMSKS motif; other site
1298917011786	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1298917011787	tRNA binding surface [nucleotide binding]; other site
1298917011788	anticodon binding site; other site
1298917011789	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1298917011790	DNA polymerase III subunit chi; Validated; Region: PRK05728
1298917011791	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1298917011792	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1298917011793	interface (dimer of trimers) [polypeptide binding]; other site
1298917011794	Substrate-binding/catalytic site; other site
1298917011795	Zn-binding sites [ion binding]; other site
1298917011796	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1298917011797	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1298917011798	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1298917011799	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1298917011800	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1298917011801	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1298917011802	DNA binding site [nucleotide binding]
1298917011803	domain linker motif; other site
1298917011804	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1298917011805	putative dimerization interface [polypeptide binding]; other site
1298917011806	putative ligand binding site [chemical binding]; other site
1298917011807	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1298917011808	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1298917011809	NADP binding site [chemical binding]; other site
1298917011810	homodimer interface [polypeptide binding]; other site
1298917011811	active site
1298917011812	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1298917011813	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1298917011814	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1298917011815	putative NAD(P) binding site [chemical binding]; other site
1298917011816	catalytic Zn binding site [ion binding]; other site
1298917011817	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1298917011818	ATP-binding site [chemical binding]; other site
1298917011819	Gluconate-6-phosphate binding site [chemical binding]; other site
1298917011820	Shikimate kinase; Region: SKI; pfam01202
1298917011821	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1298917011822	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1298917011823	putative NAD(P) binding site [chemical binding]; other site
1298917011824	putative substrate binding site [chemical binding]; other site
1298917011825	catalytic Zn binding site [ion binding]; other site
1298917011826	structural Zn binding site [ion binding]; other site
1298917011827	dimer interface [polypeptide binding]; other site
1298917011828	Winged helix-turn helix; Region: HTH_29; pfam13551
1298917011829	Homeodomain-like domain; Region: HTH_23; pfam13384
1298917011830	Homeodomain-like domain; Region: HTH_32; pfam13565
1298917011831	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1298917011832	Predicted transcriptional regulator [Transcription]; Region: COG3905
1298917011833	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
1298917011834	CcdB protein; Region: CcdB; pfam01845
1298917011835	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1298917011836	fimbrial protein SefA; Provisional; Region: PRK15228
1298917011837	PapC N-terminal domain; Region: PapC_N; pfam13954
1298917011838	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1298917011839	Enterobacteria AfaD invasin protein; Region: AfaD; cl05376
1298917011840	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1298917011841	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1298917011842	FaeA-like protein; Region: FaeA; pfam04703
1298917011843	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917011844	DNA binding residues [nucleotide binding]
1298917011845	dimerization interface [polypeptide binding]; other site
1298917011846	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1298917011847	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1298917011848	catalytic residues [active]
1298917011849	hinge region; other site
1298917011850	alpha helical domain; other site
1298917011851	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1298917011852	SdiA-regulated; Region: SdiA-regulated; cd09971
1298917011853	putative active site [active]
1298917011854	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1298917011855	DNA-binding interface [nucleotide binding]; DNA binding site
1298917011856	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1298917011857	Integrase core domain; Region: rve; pfam00665
1298917011858	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1298917011859	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1298917011860	HNH endonuclease; Region: HNH_2; pfam13391
1298917011861	hypothetical protein; Provisional; Region: PRK12378
1298917011862	hypothetical protein; Provisional; Region: PRK13687
1298917011863	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1298917011864	Uncharacterized conserved protein [Function unknown]; Region: COG3439
1298917011865	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1298917011866	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1298917011867	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1298917011868	DNA-binding site [nucleotide binding]; DNA binding site
1298917011869	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1298917011870	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1298917011871	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1298917011872	active site
1298917011873	HIGH motif; other site
1298917011874	dimer interface [polypeptide binding]; other site
1298917011875	KMSKS motif; other site
1298917011876	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1298917011877	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1298917011878	aspartate racemase; Region: asp_race; TIGR00035
1298917011879	hypothetical protein; Provisional; Region: PRK10519
1298917011880	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1298917011881	Nucleoside recognition; Region: Gate; pfam07670
1298917011882	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
1298917011883	Predicted membrane protein [Function unknown]; Region: COG2733
1298917011884	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
1298917011885	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1298917011886	putative substrate translocation pore; other site
1298917011887	putative transposase; Provisional; Region: PRK09857
1298917011888	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1298917011889	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
1298917011890	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1298917011891	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1298917011892	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1298917011893	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1298917011894	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1298917011895	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1298917011896	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
1298917011897	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
1298917011898	Uncharacterized small protein [Function unknown]; Region: COG2879
1298917011899	carbon starvation protein A; Provisional; Region: PRK15015
1298917011900	Carbon starvation protein CstA; Region: CstA; pfam02554
1298917011901	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1298917011902	methyl-accepting protein IV; Provisional; Region: PRK09793
1298917011903	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1298917011904	dimer interface [polypeptide binding]; other site
1298917011905	ligand binding site [chemical binding]; other site
1298917011906	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1298917011907	dimerization interface [polypeptide binding]; other site
1298917011908	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1298917011909	dimer interface [polypeptide binding]; other site
1298917011910	putative CheW interface [polypeptide binding]; other site
1298917011911	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1298917011912	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917011913	Walker A motif; other site
1298917011914	ATP binding site [chemical binding]; other site
1298917011915	Walker B motif; other site
1298917011916	arginine finger; other site
1298917011917	Transcriptional antiterminator [Transcription]; Region: COG3933
1298917011918	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1298917011919	active pocket/dimerization site; other site
1298917011920	active site
1298917011921	phosphorylation site [posttranslational modification]
1298917011922	PRD domain; Region: PRD; pfam00874
1298917011923	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1298917011924	active pocket/dimerization site; other site
1298917011925	active site
1298917011926	phosphorylation site [posttranslational modification]
1298917011927	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1298917011928	active site
1298917011929	phosphorylation site [posttranslational modification]
1298917011930	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1298917011931	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1298917011932	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1298917011933	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1298917011934	dimer interface [polypeptide binding]; other site
1298917011935	active site
1298917011936	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1298917011937	dimer interface [polypeptide binding]; other site
1298917011938	active site
1298917011939	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1298917011940	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1298917011941	putative active site [active]
1298917011942	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1298917011943	phosphoglycerol transferase I; Provisional; Region: PRK03776
1298917011944	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1298917011945	hypothetical protein; Provisional; Region: PRK11667
1298917011946	DNA replication protein DnaC; Validated; Region: PRK07952
1298917011947	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1298917011948	Walker A motif; other site
1298917011949	ATP binding site [chemical binding]; other site
1298917011950	Walker B motif; other site
1298917011951	primosomal protein DnaI; Provisional; Region: PRK02854
1298917011952	hypothetical protein; Provisional; Region: PRK09917
1298917011953	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1298917011954	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1298917011955	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1298917011956	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917011957	DNA binding residues [nucleotide binding]
1298917011958	dimerization interface [polypeptide binding]; other site
1298917011959	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1298917011960	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1298917011961	DNA binding residues [nucleotide binding]
1298917011962	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1298917011963	putative deacylase active site [active]
1298917011964	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1298917011965	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1298917011966	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1298917011967	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1298917011968	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1298917011969	metal binding site [ion binding]; metal-binding site
1298917011970	active site
1298917011971	I-site; other site
1298917011972	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1298917011973	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1298917011974	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1298917011975	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1298917011976	S-adenosylmethionine binding site [chemical binding]; other site
1298917011977	DNA polymerase III subunit psi; Validated; Region: PRK06856
1298917011978	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1298917011979	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1298917011980	Coenzyme A binding pocket [chemical binding]; other site
1298917011981	dUMP phosphatase; Provisional; Region: PRK09449
1298917011982	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917011983	motif II; other site
1298917011984	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1298917011985	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1298917011986	G1 box; other site
1298917011987	putative GEF interaction site [polypeptide binding]; other site
1298917011988	GTP/Mg2+ binding site [chemical binding]; other site
1298917011989	Switch I region; other site
1298917011990	G2 box; other site
1298917011991	G3 box; other site
1298917011992	Switch II region; other site
1298917011993	G4 box; other site
1298917011994	G5 box; other site
1298917011995	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1298917011996	periplasmic protein; Provisional; Region: PRK10568
1298917011997	BON domain; Region: BON; pfam04972
1298917011998	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1298917011999	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1298917012000	active site
1298917012001	nucleophile elbow; other site
1298917012002	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1298917012003	active site
1298917012004	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
1298917012005	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1298917012006	FeS/SAM binding site; other site
1298917012007	hypothetical protein; Provisional; Region: PRK10977
1298917012008	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1298917012009	intersubunit interface [polypeptide binding]; other site
1298917012010	active site
1298917012011	catalytic residue [active]
1298917012012	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1298917012013	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1298917012014	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1298917012015	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1298917012016	phosphopentomutase; Provisional; Region: PRK05362
1298917012017	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1298917012018	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1298917012019	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1298917012020	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09775
1298917012021	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1298917012022	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1298917012023	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1298917012024	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1298917012025	hypothetical protein; Provisional; Region: PRK11246
1298917012026	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1298917012027	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1298917012028	motif II; other site
1298917012029	DNA repair protein RadA; Region: sms; TIGR00416
1298917012030	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1298917012031	Walker A motif/ATP binding site; other site
1298917012032	ATP binding site [chemical binding]; other site
1298917012033	Walker B motif; other site
1298917012034	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1298917012035	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1298917012036	non-specific DNA binding site [nucleotide binding]; other site
1298917012037	salt bridge; other site
1298917012038	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1298917012039	sequence-specific DNA binding site [nucleotide binding]; other site
1298917012040	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1298917012041	active site
1298917012042	(T/H)XGH motif; other site
1298917012043	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1298917012044	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1298917012045	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1298917012046	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1298917012047	ABC transporter; Region: ABC_tran_2; pfam12848
1298917012048	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1298917012049	lytic murein transglycosylase; Provisional; Region: PRK11619
1298917012050	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1298917012051	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1298917012052	catalytic residue [active]
1298917012053	Trp operon repressor; Provisional; Region: PRK01381
1298917012054	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1298917012055	hypothetical protein; Provisional; Region: PRK10756
1298917012056	CreA protein; Region: CreA; pfam05981
1298917012057	DNA-binding response regulator CreB; Provisional; Region: PRK11083
1298917012058	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917012059	active site
1298917012060	phosphorylation site [posttranslational modification]
1298917012061	intermolecular recognition site; other site
1298917012062	dimerization interface [polypeptide binding]; other site
1298917012063	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917012064	DNA binding site [nucleotide binding]
1298917012065	sensory histidine kinase CreC; Provisional; Region: PRK11100
1298917012066	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1298917012067	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1298917012068	dimer interface [polypeptide binding]; other site
1298917012069	phosphorylation site [posttranslational modification]
1298917012070	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1298917012071	ATP binding site [chemical binding]; other site
1298917012072	Mg2+ binding site [ion binding]; other site
1298917012073	G-X-G motif; other site
1298917012074	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
1298917012075	putative fimbrial protein SthD; Provisional; Region: PRK15293
1298917012076	putative fimbrial outer membrane usher protein SthC; Provisional; Region: PRK15294
1298917012077	PapC N-terminal domain; Region: PapC_N; pfam13954
1298917012078	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1298917012079	PapC C-terminal domain; Region: PapC_C; pfam13953
1298917012080	putative fimbrial protein SthA; Provisional; Region: PRK15296
1298917012081	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1298917012082	Helix-turn-helix domain; Region: HTH_36; pfam13730
1298917012083	two-component response regulator; Provisional; Region: PRK11173
1298917012084	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1298917012085	active site
1298917012086	phosphorylation site [posttranslational modification]
1298917012087	intermolecular recognition site; other site
1298917012088	dimerization interface [polypeptide binding]; other site
1298917012089	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1298917012090	DNA binding site [nucleotide binding]
1298917012091	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1298917012092	putative RNA methyltransferase; Provisional; Region: PRK10433