-- dump date   	20140620_054726
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1132507000001	Haemolysin expression modulating protein; Region: HHA; pfam05321
1132507000002	Cre recombinase, C-terminal catalytic domain. Cre-like recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The bacteriophage P1 Cre...; Region: INT_Cre; cd00799
1132507000003	DNA binding site [nucleotide binding]
1132507000004	dimer interface [polypeptide binding]; other site
1132507000005	active site
1132507000006	Int/Topo IB signature motif; other site
1132507000007	DNA replication terminus site-binding protein (Ter protein); Region: Ter; pfam05472
1132507000008	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07632
1132507000009	Toprim domain; Region: Toprim_3; pfam13362
1132507000010	norD type: Denitrifying bacteria contain both membrane bound and periplasmic nitrate reductases. Denitrification plays a major role  in completing the nitrogen cycle by converting nitrate or nitrite to nitrogen gas. The pathway for microbial...; Region: vWA_norD_type; cd01454
1132507000011	metal ion-dependent adhesion site (MIDAS); other site
1132507000012	Protein of unknown function (DUF3150); Region: DUF3150; pfam11348
1132507000013	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507000014	Walker A motif; other site
1132507000015	ATP binding site [chemical binding]; other site
1132507000016	Walker B motif; other site
1132507000017	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1132507000018	Part of AAA domain; Region: AAA_19; pfam13245
1132507000019	Family description; Region: UvrD_C_2; pfam13538
1132507000020	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1132507000021	conjugal transfer mating pair stabilization protein TraN; Provisional; Region: PRK14877
1132507000022	TraU protein; Region: TraU; pfam06834
1132507000023	Type-F conjugative transfer system pilin assembly protein; Region: TrbC_Ftype; pfam09673
1132507000024	Sex factor F TraW protein N terminal; Region: TraW_N; cl10149
1132507000025	Signal peptidase, peptidase S26; Region: Peptidase_S26; pfam10502
1132507000026	conjugal transfer pilin processing protease TraF; Provisional; Region: PRK13838
1132507000027	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
1132507000028	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
1132507000029	Mg binding site [ion binding]; other site
1132507000030	nucleotide binding site [chemical binding]; other site
1132507000031	putative protofilament interface [polypeptide binding]; other site
1132507000032	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1132507000033	active site
1132507000034	metal binding site [ion binding]; metal-binding site
1132507000035	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1132507000036	ParB-like nuclease domain; Region: ParB; smart00470
1132507000037	ParB family; Region: ParB; pfam08775
1132507000038	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1132507000039	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1132507000040	Magnesium ion binding site [ion binding]; other site
1132507000041	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1132507000042	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1132507000043	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1132507000044	Predicted membrane protein [Function unknown]; Region: COG4325
1132507000045	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
1132507000046	BCCT family transporter; Region: BCCT; cl00569
1132507000047	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1132507000048	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
1132507000049	type-IV secretion system protein TraC; Region: TraC-F-type; TIGR02746
1132507000050	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
1132507000051	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1132507000052	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
1132507000053	TraK protein; Region: TraK; pfam06586
1132507000054	TraE protein; Region: TraE; cl05060
1132507000055	TraL protein; Region: TraL; cl06278
1132507000056	Initiator Replication protein; Region: Rep_3; cl17676
1132507000057	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1132507000058	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1132507000059	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1132507000060	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1132507000061	Domain of unknown function (DUF4165); Region: DUF4165; pfam13752
1132507000062	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
1132507000063	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507000064	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
1132507000065	Domain of unknown function (DUF4165); Region: DUF4165; pfam13752
1132507000066	Domain of unknown function (DUF4165); Region: DUF4165; pfam13752
1132507000067	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
1132507000068	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
1132507000069	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1132507000070	Active Sites [active]
1132507000071	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1132507000072	Protein of unknown function (DUF3085); Region: DUF3085; pfam11284
1132507000073	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1132507000074	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1132507000075	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1132507000076	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1132507000077	Cl binding site [ion binding]; other site
1132507000078	oligomer interface [polypeptide binding]; other site
1132507000079	Predicted periplasmic protein [Function unknown]; Region: COG3698
1132507000080	small toxic polypeptide; Provisional; Region: PRK09738
1132507000081	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1132507000082	envelope glycoprotein I; Provisional; Region: PHA03291
1132507000083	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1132507000084	Nuclease-related domain; Region: NERD; pfam08378
1132507000085	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
1132507000086	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1132507000087	tandem repeat interface [polypeptide binding]; other site
1132507000088	oligomer interface [polypeptide binding]; other site
1132507000089	active site residues [active]
1132507000090	Domain of unknown function (DUF4400); Region: DUF4400; pfam14348
1132507000091	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
1132507000092	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
1132507000093	Putative helicase; Region: TraI_2; pfam07514
1132507000094	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
1132507000095	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1132507000096	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1132507000097	catalytic residues [active]
1132507000098	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1132507000099	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1132507000100	active site
1132507000101	DNA binding site [nucleotide binding]
1132507000102	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1132507000103	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1132507000104	Catalytic site [active]
1132507000105	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
1132507000106	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; cl09156
1132507000107	citrate-proton symporter; Provisional; Region: PRK15075
1132507000108	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507000109	putative substrate translocation pore; other site
1132507000110	tricarballylate utilization protein B; Provisional; Region: PRK15033
1132507000111	tricarballylate dehydrogenase; Validated; Region: PRK08274
1132507000112	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1132507000113	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507000114	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1132507000115	putative dimerization interface [polypeptide binding]; other site
1132507000116	Winged helix-turn helix; Region: HTH_29; pfam13551
1132507000117	Helix-turn-helix domain; Region: HTH_28; pfam13518
1132507000118	Homeodomain-like domain; Region: HTH_32; pfam13565
1132507000119	Integrase core domain; Region: rve; pfam00665
1132507000120	Putative catalytic domain of uncharacterized hypothetical proteins with one or two copies of the HKD motif; Region: PLDc_unchar6; cd09176
1132507000121	PLD-like domain; Region: PLDc_2; pfam13091
1132507000122	putative homodimer interface [polypeptide binding]; other site
1132507000123	putative active site [active]
1132507000124	catalytic site [active]
1132507000125	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1132507000126	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1132507000127	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507000128	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507000129	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1132507000130	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507000131	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507000132	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1132507000133	putative substrate translocation pore; other site
1132507000134	tetracycline repressor protein TetR; Provisional; Region: PRK13756
1132507000135	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507000136	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
1132507000137	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1132507000138	dimerization interface [polypeptide binding]; other site
1132507000139	putative DNA binding site [nucleotide binding]; other site
1132507000140	putative Zn2+ binding site [ion binding]; other site
1132507000141	homoserine dehydrogenase; Provisional; Region: PRK06349
1132507000142	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1132507000143	Sodium/glutamate symporter; Region: Glt_symporter; pfam03616
1132507000144	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507000145	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1132507000146	Staphylococcal nuclease homologues; Region: SNc; smart00318
1132507000147	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
1132507000148	Catalytic site; other site
1132507000149	DNA cytosine methylase; Provisional; Region: PRK10458
1132507000150	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1132507000151	cofactor binding site; other site
1132507000152	DNA binding site [nucleotide binding]
1132507000153	substrate interaction site [chemical binding]; other site
1132507000154	Protein of unknown function (DUF1173); Region: DUF1173; pfam06666
1132507000155	Predicted ATPase [General function prediction only]; Region: COG3910
1132507000156	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1132507000157	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1132507000158	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1132507000159	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1132507000160	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1132507000161	HNH endonuclease; Region: HNH_2; pfam13391
1132507000162	HNH endonuclease; Region: HNH_2; pfam13391
1132507000163	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
1132507000164	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1132507000165	Walker A/P-loop; other site
1132507000166	ATP binding site [chemical binding]; other site
1132507000167	Q-loop/lid; other site
1132507000168	ABC transporter signature motif; other site
1132507000169	Walker B; other site
1132507000170	D-loop; other site
1132507000171	H-loop/switch region; other site
1132507000172	urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411
1132507000173	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1132507000174	Walker A/P-loop; other site
1132507000175	ATP binding site [chemical binding]; other site
1132507000176	Q-loop/lid; other site
1132507000177	ABC transporter signature motif; other site
1132507000178	Walker B; other site
1132507000179	D-loop; other site
1132507000180	H-loop/switch region; other site
1132507000181	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
1132507000182	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1132507000183	TM-ABC transporter signature motif; other site
1132507000184	HEAT repeats; Region: HEAT_2; pfam13646
1132507000185	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1132507000186	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1132507000187	TM-ABC transporter signature motif; other site
1132507000188	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
1132507000189	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
1132507000190	putative ligand binding site [chemical binding]; other site
1132507000191	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1132507000192	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507000193	DNA-binding site [nucleotide binding]; DNA binding site
1132507000194	FCD domain; Region: FCD; pfam07729
1132507000195	urea carboxylase; Region: urea_carbox; TIGR02712
1132507000196	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1132507000197	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1132507000198	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1132507000199	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
1132507000200	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1132507000201	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1132507000202	carboxyltransferase (CT) interaction site; other site
1132507000203	biotinylation site [posttranslational modification]; other site
1132507000204	allophanate hydrolase; Provisional; Region: PRK08186
1132507000205	Amidase; Region: Amidase; cl11426
1132507000206	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1132507000207	replication protein; Provisional; Region: PRK13742
1132507000208	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1132507000209	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1132507000210	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1132507000211	putative catalytic residues [active]
1132507000212	putative nucleotide binding site [chemical binding]; other site
1132507000213	putative aspartate binding site [chemical binding]; other site
1132507000214	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1132507000215	dimer interface [polypeptide binding]; other site
1132507000216	putative threonine allosteric regulatory site; other site
1132507000217	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1132507000218	putative threonine allosteric regulatory site; other site
1132507000219	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1132507000220	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1132507000221	homoserine kinase; Provisional; Region: PRK01212
1132507000222	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1132507000223	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1132507000224	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1132507000225	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507000226	catalytic residue [active]
1132507000227	hypothetical protein; Validated; Region: PRK02101
1132507000228	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1132507000229	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1132507000230	transaldolase-like protein; Provisional; Region: PTZ00411
1132507000231	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1132507000232	active site
1132507000233	dimer interface [polypeptide binding]; other site
1132507000234	catalytic residue [active]
1132507000235	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1132507000236	MPT binding site; other site
1132507000237	trimer interface [polypeptide binding]; other site
1132507000238	hypothetical protein; Provisional; Region: PRK10659
1132507000239	hypothetical protein; Provisional; Region: PRK10236
1132507000240	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1132507000241	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1132507000242	Protein of unknown function (DUF2541); Region: DUF2541; cl08090
1132507000243	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1132507000244	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1132507000245	nucleotide binding site [chemical binding]; other site
1132507000246	chaperone protein DnaJ; Provisional; Region: PRK10767
1132507000247	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1132507000248	HSP70 interaction site [polypeptide binding]; other site
1132507000249	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1132507000250	substrate binding site [polypeptide binding]; other site
1132507000251	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1132507000252	Zn binding sites [ion binding]; other site
1132507000253	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1132507000254	dimer interface [polypeptide binding]; other site
1132507000255	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507000256	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507000257	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507000258	dimerization interface [polypeptide binding]; other site
1132507000259	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1132507000260	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1132507000261	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1132507000262	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1132507000263	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
1132507000264	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1132507000265	active site
1132507000266	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1132507000267	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1132507000268	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1132507000269	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1132507000270	Helix-turn-helix domain; Region: HTH_36; pfam13730
1132507000271	fimbrial protein BcfA; Provisional; Region: PRK15187
1132507000272	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
1132507000273	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507000274	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507000275	PapC N-terminal domain; Region: PapC_N; pfam13954
1132507000276	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1132507000277	fimbrial protein BcfD; Provisional; Region: PRK15189
1132507000278	fimbrial protein BcfE; Provisional; Region: PRK15190
1132507000279	fimbrial protein BcfF; Provisional; Region: PRK15191
1132507000280	fimbrial chaperone BcfG; Provisional; Region: PRK15192
1132507000281	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507000282	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507000283	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1132507000284	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1132507000285	catalytic residues [active]
1132507000286	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1132507000287	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507000288	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507000289	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507000290	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1132507000291	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1132507000292	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1132507000293	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1132507000294	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1132507000295	active site
1132507000296	metal binding site [ion binding]; metal-binding site
1132507000297	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1132507000298	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
1132507000299	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1132507000300	Sulfatase; Region: Sulfatase; pfam00884
1132507000301	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1132507000302	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507000303	FeS/SAM binding site; other site
1132507000304	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1132507000305	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1132507000306	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1132507000307	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1132507000308	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507000309	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1132507000310	putative dimerization interface [polypeptide binding]; other site
1132507000311	putative alpha-glucosidase; Provisional; Region: PRK10658
1132507000312	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1132507000313	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
1132507000314	putative active site [active]
1132507000315	putative catalytic site [active]
1132507000316	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1132507000317	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1132507000318	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1132507000319	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
1132507000320	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1132507000321	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1132507000322	active site
1132507000323	Riboflavin kinase; Region: Flavokinase; smart00904
1132507000324	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1132507000325	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1132507000326	active site
1132507000327	HIGH motif; other site
1132507000328	nucleotide binding site [chemical binding]; other site
1132507000329	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1132507000330	active site
1132507000331	KMSKS motif; other site
1132507000332	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1132507000333	tRNA binding surface [nucleotide binding]; other site
1132507000334	anticodon binding site; other site
1132507000335	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1132507000336	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1132507000337	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1132507000338	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1132507000339	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1132507000340	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1132507000341	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1132507000342	active site
1132507000343	tetramer interface [polypeptide binding]; other site
1132507000344	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1132507000345	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507000346	active site
1132507000347	phosphorylation site [posttranslational modification]
1132507000348	intermolecular recognition site; other site
1132507000349	dimerization interface [polypeptide binding]; other site
1132507000350	Transcriptional regulator; Region: CitT; pfam12431
1132507000351	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1132507000352	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1132507000353	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507000354	ATP binding site [chemical binding]; other site
1132507000355	Mg2+ binding site [ion binding]; other site
1132507000356	G-X-G motif; other site
1132507000357	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1132507000358	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1132507000359	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1132507000360	active site
1132507000361	catalytic residues [active]
1132507000362	metal binding site [ion binding]; metal-binding site
1132507000363	homodimer binding site [polypeptide binding]; other site
1132507000364	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1132507000365	carboxyltransferase (CT) interaction site; other site
1132507000366	biotinylation site [posttranslational modification]; other site
1132507000367	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1132507000368	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
1132507000369	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1132507000370	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1132507000371	putative active site [active]
1132507000372	(T/H)XGH motif; other site
1132507000373	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1132507000374	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1132507000375	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1132507000376	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1132507000377	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1132507000378	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
1132507000379	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1132507000380	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1132507000381	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1132507000382	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1132507000383	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1132507000384	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1132507000385	catalytic site [active]
1132507000386	subunit interface [polypeptide binding]; other site
1132507000387	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1132507000388	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1132507000389	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1132507000390	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1132507000391	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1132507000392	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1132507000393	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1132507000394	IMP binding site; other site
1132507000395	dimer interface [polypeptide binding]; other site
1132507000396	interdomain contacts; other site
1132507000397	partial ornithine binding site; other site
1132507000398	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
1132507000399	carnitine operon protein CaiE; Provisional; Region: PRK13627
1132507000400	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1132507000401	putative trimer interface [polypeptide binding]; other site
1132507000402	putative metal binding site [ion binding]; other site
1132507000403	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
1132507000404	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1132507000405	substrate binding site [chemical binding]; other site
1132507000406	oxyanion hole (OAH) forming residues; other site
1132507000407	trimer interface [polypeptide binding]; other site
1132507000408	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
1132507000409	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
1132507000410	acyl-activating enzyme (AAE) consensus motif; other site
1132507000411	putative AMP binding site [chemical binding]; other site
1132507000412	putative active site [active]
1132507000413	putative CoA binding site [chemical binding]; other site
1132507000414	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
1132507000415	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1132507000416	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
1132507000417	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1132507000418	active site
1132507000419	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
1132507000420	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1132507000421	Ligand binding site [chemical binding]; other site
1132507000422	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1132507000423	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
1132507000424	Electron transfer flavoprotein domain; Region: ETF; smart00893
1132507000425	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1132507000426	putative oxidoreductase FixC; Provisional; Region: PRK10157
1132507000427	ferredoxin-like protein FixX; Provisional; Region: PRK15449
1132507000428	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507000429	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1132507000430	putative substrate translocation pore; other site
1132507000431	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1132507000432	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1132507000433	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1132507000434	Sulfatase; Region: Sulfatase; cl17466
1132507000435	Sulfatase; Region: Sulfatase; cl17466
1132507000436	Sulfatase; Region: Sulfatase; cl17466
1132507000437	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1132507000438	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1132507000439	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1132507000440	TrkA-N domain; Region: TrkA_N; pfam02254
1132507000441	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1132507000442	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1132507000443	folate binding site [chemical binding]; other site
1132507000444	NADP+ binding site [chemical binding]; other site
1132507000445	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1132507000446	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1132507000447	active site
1132507000448	metal binding site [ion binding]; metal-binding site
1132507000449	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1132507000450	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1132507000451	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1132507000452	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1132507000453	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1132507000454	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1132507000455	SurA N-terminal domain; Region: SurA_N; pfam09312
1132507000456	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1132507000457	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1132507000458	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1132507000459	OstA-like protein; Region: OstA; pfam03968
1132507000460	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1132507000461	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1132507000462	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1132507000463	putative metal binding site [ion binding]; other site
1132507000464	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1132507000465	HSP70 interaction site [polypeptide binding]; other site
1132507000466	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1132507000467	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1132507000468	active site
1132507000469	ATP-dependent helicase HepA; Validated; Region: PRK04914
1132507000470	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507000471	ATP binding site [chemical binding]; other site
1132507000472	putative Mg++ binding site [ion binding]; other site
1132507000473	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507000474	nucleotide binding region [chemical binding]; other site
1132507000475	ATP-binding site [chemical binding]; other site
1132507000476	DNA polymerase II; Reviewed; Region: PRK05762
1132507000477	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1132507000478	active site
1132507000479	catalytic site [active]
1132507000480	substrate binding site [chemical binding]; other site
1132507000481	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1132507000482	active site
1132507000483	metal-binding site
1132507000484	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cl00630
1132507000485	putative active site [active]
1132507000486	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1132507000487	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1132507000488	Probable transposase; Region: OrfB_IS605; pfam01385
1132507000489	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1132507000490	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1132507000491	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1132507000492	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1132507000493	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1132507000494	intersubunit interface [polypeptide binding]; other site
1132507000495	active site
1132507000496	Zn2+ binding site [ion binding]; other site
1132507000497	L-arabinose isomerase; Provisional; Region: PRK02929
1132507000498	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1132507000499	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1132507000500	trimer interface [polypeptide binding]; other site
1132507000501	putative substrate binding site [chemical binding]; other site
1132507000502	putative metal binding site [ion binding]; other site
1132507000503	ribulokinase; Provisional; Region: PRK04123
1132507000504	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1132507000505	N- and C-terminal domain interface [polypeptide binding]; other site
1132507000506	active site
1132507000507	MgATP binding site [chemical binding]; other site
1132507000508	catalytic site [active]
1132507000509	metal binding site [ion binding]; metal-binding site
1132507000510	carbohydrate binding site [chemical binding]; other site
1132507000511	homodimer interface [polypeptide binding]; other site
1132507000512	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1132507000513	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1132507000514	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507000515	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507000516	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1132507000517	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1132507000518	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1132507000519	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1132507000520	Walker A/P-loop; other site
1132507000521	ATP binding site [chemical binding]; other site
1132507000522	Q-loop/lid; other site
1132507000523	ABC transporter signature motif; other site
1132507000524	Walker B; other site
1132507000525	D-loop; other site
1132507000526	H-loop/switch region; other site
1132507000527	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1132507000528	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507000529	dimer interface [polypeptide binding]; other site
1132507000530	conserved gate region; other site
1132507000531	putative PBP binding loops; other site
1132507000532	ABC-ATPase subunit interface; other site
1132507000533	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507000534	dimer interface [polypeptide binding]; other site
1132507000535	conserved gate region; other site
1132507000536	putative PBP binding loops; other site
1132507000537	ABC-ATPase subunit interface; other site
1132507000538	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1132507000539	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1132507000540	transcriptional regulator SgrR; Provisional; Region: PRK13626
1132507000541	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1132507000542	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1132507000543	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1132507000544	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1132507000545	substrate binding site [chemical binding]; other site
1132507000546	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1132507000547	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1132507000548	substrate binding site [chemical binding]; other site
1132507000549	ligand binding site [chemical binding]; other site
1132507000550	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1132507000551	tartrate dehydrogenase; Region: TTC; TIGR02089
1132507000552	2-isopropylmalate synthase; Validated; Region: PRK00915
1132507000553	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1132507000554	active site
1132507000555	catalytic residues [active]
1132507000556	metal binding site [ion binding]; metal-binding site
1132507000557	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1132507000558	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1132507000559	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507000560	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1132507000561	putative substrate binding pocket [chemical binding]; other site
1132507000562	putative dimerization interface [polypeptide binding]; other site
1132507000563	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1132507000564	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1132507000565	PYR/PP interface [polypeptide binding]; other site
1132507000566	dimer interface [polypeptide binding]; other site
1132507000567	TPP binding site [chemical binding]; other site
1132507000568	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1132507000569	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1132507000570	TPP-binding site [chemical binding]; other site
1132507000571	dimer interface [polypeptide binding]; other site
1132507000572	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1132507000573	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1132507000574	putative valine binding site [chemical binding]; other site
1132507000575	dimer interface [polypeptide binding]; other site
1132507000576	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1132507000577	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1132507000578	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507000579	DNA binding site [nucleotide binding]
1132507000580	domain linker motif; other site
1132507000581	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1132507000582	dimerization interface [polypeptide binding]; other site
1132507000583	ligand binding site [chemical binding]; other site
1132507000584	mraZ protein; Region: TIGR00242
1132507000585	MraZ protein; Region: MraZ; pfam02381
1132507000586	MraZ protein; Region: MraZ; pfam02381
1132507000587	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1132507000588	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1132507000589	cell division protein FtsL; Provisional; Region: PRK10772
1132507000590	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1132507000591	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1132507000592	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1132507000593	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1132507000594	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1132507000595	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1132507000596	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1132507000597	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1132507000598	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1132507000599	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1132507000600	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1132507000601	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1132507000602	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1132507000603	Mg++ binding site [ion binding]; other site
1132507000604	putative catalytic motif [active]
1132507000605	putative substrate binding site [chemical binding]; other site
1132507000606	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1132507000607	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1132507000608	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1132507000609	cell division protein FtsW; Provisional; Region: PRK10774
1132507000610	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1132507000611	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1132507000612	active site
1132507000613	homodimer interface [polypeptide binding]; other site
1132507000614	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1132507000615	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1132507000616	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1132507000617	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1132507000618	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1132507000619	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1132507000620	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1132507000621	cell division protein FtsQ; Provisional; Region: PRK10775
1132507000622	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1132507000623	Cell division protein FtsQ; Region: FtsQ; pfam03799
1132507000624	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1132507000625	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1132507000626	Cell division protein FtsA; Region: FtsA; pfam14450
1132507000627	cell division protein FtsZ; Validated; Region: PRK09330
1132507000628	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1132507000629	nucleotide binding site [chemical binding]; other site
1132507000630	SulA interaction site; other site
1132507000631	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
1132507000632	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1132507000633	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1132507000634	SecA regulator SecM; Provisional; Region: PRK02943
1132507000635	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1132507000636	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1132507000637	SEC-C motif; Region: SEC-C; pfam02810
1132507000638	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1132507000639	active site
1132507000640	8-oxo-dGMP binding site [chemical binding]; other site
1132507000641	nudix motif; other site
1132507000642	metal binding site [ion binding]; metal-binding site
1132507000643	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1132507000644	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1132507000645	active site
1132507000646	catalytic tetrad [active]
1132507000647	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507000648	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507000649	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1132507000650	putative effector binding pocket; other site
1132507000651	putative dimerization interface [polypeptide binding]; other site
1132507000652	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1132507000653	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
1132507000654	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1132507000655	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1132507000656	CoA-binding site [chemical binding]; other site
1132507000657	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1132507000658	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1132507000659	active site
1132507000660	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1132507000661	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1132507000662	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1132507000663	hypothetical protein; Provisional; Region: PRK10436
1132507000664	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1132507000665	Walker A motif; other site
1132507000666	ATP binding site [chemical binding]; other site
1132507000667	Walker B motif; other site
1132507000668	putative major pilin subunit; Provisional; Region: PRK10574
1132507000669	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1132507000670	Pilin (bacterial filament); Region: Pilin; pfam00114
1132507000671	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1132507000672	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1132507000673	dimerization interface [polypeptide binding]; other site
1132507000674	active site
1132507000675	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1132507000676	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1132507000677	amidase catalytic site [active]
1132507000678	Zn binding residues [ion binding]; other site
1132507000679	substrate binding site [chemical binding]; other site
1132507000680	regulatory protein AmpE; Provisional; Region: PRK10987
1132507000681	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1132507000682	active site
1132507000683	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1132507000684	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507000685	putative substrate translocation pore; other site
1132507000686	aromatic amino acid transporter; Provisional; Region: PRK10238
1132507000687	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1132507000688	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507000689	DNA-binding site [nucleotide binding]; DNA binding site
1132507000690	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1132507000691	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1132507000692	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1132507000693	dimer interface [polypeptide binding]; other site
1132507000694	TPP-binding site [chemical binding]; other site
1132507000695	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1132507000696	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1132507000697	E3 interaction surface; other site
1132507000698	lipoyl attachment site [posttranslational modification]; other site
1132507000699	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1132507000700	E3 interaction surface; other site
1132507000701	lipoyl attachment site [posttranslational modification]; other site
1132507000702	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1132507000703	E3 interaction surface; other site
1132507000704	lipoyl attachment site [posttranslational modification]; other site
1132507000705	e3 binding domain; Region: E3_binding; pfam02817
1132507000706	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1132507000707	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1132507000708	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1132507000709	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507000710	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1132507000711	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1132507000712	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
1132507000713	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1132507000714	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1132507000715	substrate binding site [chemical binding]; other site
1132507000716	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1132507000717	substrate binding site [chemical binding]; other site
1132507000718	ligand binding site [chemical binding]; other site
1132507000719	hypothetical protein; Provisional; Region: PRK05248
1132507000720	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
1132507000721	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1132507000722	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1132507000723	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
1132507000724	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1132507000725	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1132507000726	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507000727	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1132507000728	spermidine synthase; Provisional; Region: PRK00811
1132507000729	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507000730	S-adenosylmethionine binding site [chemical binding]; other site
1132507000731	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1132507000732	multicopper oxidase; Provisional; Region: PRK10965
1132507000733	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1132507000734	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1132507000735	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1132507000736	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1132507000737	Trp docking motif [polypeptide binding]; other site
1132507000738	putative active site [active]
1132507000739	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1132507000740	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1132507000741	active site
1132507000742	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1132507000743	active site clefts [active]
1132507000744	zinc binding site [ion binding]; other site
1132507000745	dimer interface [polypeptide binding]; other site
1132507000746	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1132507000747	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1132507000748	Walker A/P-loop; other site
1132507000749	ATP binding site [chemical binding]; other site
1132507000750	Q-loop/lid; other site
1132507000751	ABC transporter signature motif; other site
1132507000752	Walker B; other site
1132507000753	D-loop; other site
1132507000754	H-loop/switch region; other site
1132507000755	inner membrane transport permease; Provisional; Region: PRK15066
1132507000756	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1132507000757	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1132507000758	active pocket/dimerization site; other site
1132507000759	active site
1132507000760	phosphorylation site [posttranslational modification]
1132507000761	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1132507000762	putative active site [active]
1132507000763	putative metal binding site [ion binding]; other site
1132507000764	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1132507000765	tetramerization interface [polypeptide binding]; other site
1132507000766	active site
1132507000767	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1132507000768	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1132507000769	active site
1132507000770	ATP-binding site [chemical binding]; other site
1132507000771	pantoate-binding site; other site
1132507000772	HXXH motif; other site
1132507000773	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1132507000774	oligomerization interface [polypeptide binding]; other site
1132507000775	active site
1132507000776	metal binding site [ion binding]; metal-binding site
1132507000777	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
1132507000778	putative fimbrial protein StaF; Provisional; Region: PRK15262
1132507000779	putative fimbrial protein StaE; Provisional; Region: PRK15263
1132507000780	putative fimbrial protein StaD; Provisional; Region: PRK15241
1132507000781	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
1132507000782	PapC N-terminal domain; Region: PapC_N; pfam13954
1132507000783	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1132507000784	PapC C-terminal domain; Region: PapC_C; pfam13953
1132507000785	putative chaperone protein EcpD; Provisional; Region: PRK09926
1132507000786	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507000787	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507000788	putative fimbrial protein StaA; Provisional; Region: PRK15239
1132507000789	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1132507000790	catalytic center binding site [active]
1132507000791	ATP binding site [chemical binding]; other site
1132507000792	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
1132507000793	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1132507000794	active site
1132507000795	NTP binding site [chemical binding]; other site
1132507000796	metal binding triad [ion binding]; metal-binding site
1132507000797	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1132507000798	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1132507000799	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1132507000800	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1132507000801	active site
1132507000802	nucleotide binding site [chemical binding]; other site
1132507000803	HIGH motif; other site
1132507000804	KMSKS motif; other site
1132507000805	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1132507000806	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1132507000807	2'-5' RNA ligase; Provisional; Region: PRK15124
1132507000808	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1132507000809	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1132507000810	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1132507000811	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507000812	ATP binding site [chemical binding]; other site
1132507000813	putative Mg++ binding site [ion binding]; other site
1132507000814	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507000815	nucleotide binding region [chemical binding]; other site
1132507000816	ATP-binding site [chemical binding]; other site
1132507000817	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1132507000818	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1132507000819	Transglycosylase; Region: Transgly; pfam00912
1132507000820	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1132507000821	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1132507000822	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1132507000823	Walker A/P-loop; other site
1132507000824	ATP binding site [chemical binding]; other site
1132507000825	Q-loop/lid; other site
1132507000826	ABC transporter signature motif; other site
1132507000827	Walker B; other site
1132507000828	D-loop; other site
1132507000829	H-loop/switch region; other site
1132507000830	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1132507000831	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1132507000832	siderophore binding site; other site
1132507000833	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1132507000834	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1132507000835	ABC-ATPase subunit  interface; other site
1132507000836	dimer interface [polypeptide binding]; other site
1132507000837	putative PBP binding regions; other site
1132507000838	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1132507000839	ABC-ATPase subunit  interface; other site
1132507000840	dimer interface [polypeptide binding]; other site
1132507000841	putative PBP binding regions; other site
1132507000842	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1132507000843	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1132507000844	inhibitor-cofactor binding pocket; inhibition site
1132507000845	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507000846	catalytic residue [active]
1132507000847	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1132507000848	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1132507000849	Cl- selectivity filter; other site
1132507000850	Cl- binding residues [ion binding]; other site
1132507000851	pore gating glutamate residue; other site
1132507000852	dimer interface [polypeptide binding]; other site
1132507000853	H+/Cl- coupling transport residue; other site
1132507000854	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1132507000855	hypothetical protein; Provisional; Region: PRK10578
1132507000856	UPF0126 domain; Region: UPF0126; pfam03458
1132507000857	UPF0126 domain; Region: UPF0126; pfam03458
1132507000858	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1132507000859	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1132507000860	cobalamin binding residues [chemical binding]; other site
1132507000861	putative BtuC binding residues; other site
1132507000862	dimer interface [polypeptide binding]; other site
1132507000863	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1132507000864	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1132507000865	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1132507000866	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1132507000867	Zn2+ binding site [ion binding]; other site
1132507000868	Mg2+ binding site [ion binding]; other site
1132507000869	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1132507000870	serine endoprotease; Provisional; Region: PRK10942
1132507000871	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1132507000872	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1132507000873	protein binding site [polypeptide binding]; other site
1132507000874	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1132507000875	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1132507000876	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1132507000877	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1132507000878	hypothetical protein; Provisional; Region: PRK13677
1132507000879	metabolite-proton symporter; Region: 2A0106; TIGR00883
1132507000880	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507000881	putative substrate translocation pore; other site
1132507000882	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1132507000883	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1132507000884	trimer interface [polypeptide binding]; other site
1132507000885	active site
1132507000886	substrate binding site [chemical binding]; other site
1132507000887	CoA binding site [chemical binding]; other site
1132507000888	PII uridylyl-transferase; Provisional; Region: PRK05007
1132507000889	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1132507000890	metal binding triad; other site
1132507000891	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1132507000892	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1132507000893	Zn2+ binding site [ion binding]; other site
1132507000894	Mg2+ binding site [ion binding]; other site
1132507000895	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1132507000896	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1132507000897	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1132507000898	active site
1132507000899	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1132507000900	rRNA interaction site [nucleotide binding]; other site
1132507000901	S8 interaction site; other site
1132507000902	putative laminin-1 binding site; other site
1132507000903	elongation factor Ts; Provisional; Region: tsf; PRK09377
1132507000904	UBA/TS-N domain; Region: UBA; pfam00627
1132507000905	Elongation factor TS; Region: EF_TS; pfam00889
1132507000906	Elongation factor TS; Region: EF_TS; pfam00889
1132507000907	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1132507000908	putative nucleotide binding site [chemical binding]; other site
1132507000909	uridine monophosphate binding site [chemical binding]; other site
1132507000910	homohexameric interface [polypeptide binding]; other site
1132507000911	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1132507000912	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1132507000913	hinge region; other site
1132507000914	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1132507000915	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1132507000916	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1132507000917	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1132507000918	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1132507000919	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1132507000920	catalytic residue [active]
1132507000921	putative FPP diphosphate  binding site; other site
1132507000922	putative FPP binding hydrophobic cleft; other site
1132507000923	dimer interface [polypeptide binding]; other site
1132507000924	putative IPP diphosphate binding site; other site
1132507000925	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1132507000926	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1132507000927	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1132507000928	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1132507000929	active site
1132507000930	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1132507000931	protein binding site [polypeptide binding]; other site
1132507000932	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1132507000933	protein binding site [polypeptide binding]; other site
1132507000934	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1132507000935	putative substrate binding region [chemical binding]; other site
1132507000936	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1132507000937	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1132507000938	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1132507000939	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1132507000940	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1132507000941	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1132507000942	Surface antigen; Region: Bac_surface_Ag; pfam01103
1132507000943	periplasmic chaperone; Provisional; Region: PRK10780
1132507000944	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1132507000945	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1132507000946	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1132507000947	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1132507000948	trimer interface [polypeptide binding]; other site
1132507000949	active site
1132507000950	UDP-GlcNAc binding site [chemical binding]; other site
1132507000951	lipid binding site [chemical binding]; lipid-binding site
1132507000952	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1132507000953	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1132507000954	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1132507000955	active site
1132507000956	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1132507000957	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1132507000958	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1132507000959	RNA/DNA hybrid binding site [nucleotide binding]; other site
1132507000960	active site
1132507000961	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1132507000962	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1132507000963	putative active site [active]
1132507000964	putative PHP Thumb interface [polypeptide binding]; other site
1132507000965	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1132507000966	generic binding surface II; other site
1132507000967	generic binding surface I; other site
1132507000968	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1132507000969	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1132507000970	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507000971	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1132507000972	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1132507000973	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1132507000974	homodimer interface [polypeptide binding]; other site
1132507000975	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507000976	catalytic residue [active]
1132507000977	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1132507000978	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1132507000979	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1132507000980	putative metal binding site [ion binding]; other site
1132507000981	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1132507000982	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1132507000983	Ligand Binding Site [chemical binding]; other site
1132507000984	TilS substrate binding domain; Region: TilS; pfam09179
1132507000985	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1132507000986	Modulator of Rho-dependent transcription termination (ROF); Region: ROF; cl09210
1132507000987	hypothetical protein; Provisional; Region: PRK04964
1132507000988	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1132507000989	hypothetical protein; Provisional; Region: PRK09256
1132507000990	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1132507000991	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1132507000992	NlpE N-terminal domain; Region: NlpE; pfam04170
1132507000993	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507000994	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1132507000995	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1132507000996	dimer interface [polypeptide binding]; other site
1132507000997	motif 1; other site
1132507000998	active site
1132507000999	motif 2; other site
1132507001000	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1132507001001	putative deacylase active site [active]
1132507001002	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1132507001003	active site
1132507001004	motif 3; other site
1132507001005	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1132507001006	anticodon binding site; other site
1132507001007	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1132507001008	homodimer interaction site [polypeptide binding]; other site
1132507001009	cofactor binding site; other site
1132507001010	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1132507001011	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1132507001012	lipoprotein, YaeC family; Region: TIGR00363
1132507001013	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507001014	dimer interface [polypeptide binding]; other site
1132507001015	conserved gate region; other site
1132507001016	ABC-ATPase subunit interface; other site
1132507001017	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1132507001018	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1132507001019	Walker A/P-loop; other site
1132507001020	ATP binding site [chemical binding]; other site
1132507001021	Q-loop/lid; other site
1132507001022	ABC transporter signature motif; other site
1132507001023	Walker B; other site
1132507001024	D-loop; other site
1132507001025	H-loop/switch region; other site
1132507001026	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1132507001027	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1132507001028	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507001029	active site
1132507001030	motif I; other site
1132507001031	motif II; other site
1132507001032	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1132507001033	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1132507001034	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507001035	putative substrate translocation pore; other site
1132507001036	lipoprotein; Provisional; Region: PRK10759
1132507001037	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1132507001038	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1132507001039	domain interface [polypeptide binding]; other site
1132507001040	putative active site [active]
1132507001041	catalytic site [active]
1132507001042	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1132507001043	domain interface [polypeptide binding]; other site
1132507001044	putative active site [active]
1132507001045	catalytic site [active]
1132507001046	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1132507001047	CoA binding domain; Region: CoA_binding_2; pfam13380
1132507001048	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1132507001049	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1132507001050	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1132507001051	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507001052	Coenzyme A binding pocket [chemical binding]; other site
1132507001053	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1132507001054	thioredoxin 2; Provisional; Region: PRK10996
1132507001055	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1132507001056	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1132507001057	catalytic residues [active]
1132507001058	putative methyltransferase; Provisional; Region: PRK10864
1132507001059	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1132507001060	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1132507001061	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1132507001062	ligand binding site [chemical binding]; other site
1132507001063	active site
1132507001064	UGI interface [polypeptide binding]; other site
1132507001065	catalytic site [active]
1132507001066	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1132507001067	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
1132507001068	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507001069	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507001070	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1132507001071	dimerization interface [polypeptide binding]; other site
1132507001072	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1132507001073	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1132507001074	ATP binding site [chemical binding]; other site
1132507001075	Mg++ binding site [ion binding]; other site
1132507001076	motif III; other site
1132507001077	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507001078	nucleotide binding region [chemical binding]; other site
1132507001079	ATP-binding site [chemical binding]; other site
1132507001080	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1132507001081	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507001082	S-adenosylmethionine binding site [chemical binding]; other site
1132507001083	L-aspartate oxidase; Provisional; Region: PRK09077
1132507001084	L-aspartate oxidase; Provisional; Region: PRK06175
1132507001085	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1132507001086	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1132507001087	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1132507001088	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1132507001089	DNA binding residues [nucleotide binding]
1132507001090	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1132507001091	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1132507001092	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1132507001093	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1132507001094	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1132507001095	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1132507001096	GTP-binding protein LepA; Provisional; Region: PRK05433
1132507001097	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1132507001098	G1 box; other site
1132507001099	putative GEF interaction site [polypeptide binding]; other site
1132507001100	GTP/Mg2+ binding site [chemical binding]; other site
1132507001101	Switch I region; other site
1132507001102	G2 box; other site
1132507001103	G3 box; other site
1132507001104	Switch II region; other site
1132507001105	G4 box; other site
1132507001106	G5 box; other site
1132507001107	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1132507001108	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1132507001109	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1132507001110	signal peptidase I; Provisional; Region: PRK10861
1132507001111	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1132507001112	Catalytic site [active]
1132507001113	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1132507001114	ribonuclease III; Reviewed; Region: rnc; PRK00102
1132507001115	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1132507001116	dimerization interface [polypeptide binding]; other site
1132507001117	active site
1132507001118	metal binding site [ion binding]; metal-binding site
1132507001119	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1132507001120	dsRNA binding site [nucleotide binding]; other site
1132507001121	GTPase Era; Reviewed; Region: era; PRK00089
1132507001122	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1132507001123	G1 box; other site
1132507001124	GTP/Mg2+ binding site [chemical binding]; other site
1132507001125	Switch I region; other site
1132507001126	G2 box; other site
1132507001127	Switch II region; other site
1132507001128	G3 box; other site
1132507001129	G4 box; other site
1132507001130	G5 box; other site
1132507001131	KH domain; Region: KH_2; pfam07650
1132507001132	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1132507001133	Recombination protein O N terminal; Region: RecO_N; pfam11967
1132507001134	Recombination protein O C terminal; Region: RecO_C; pfam02565
1132507001135	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1132507001136	active site
1132507001137	hydrophilic channel; other site
1132507001138	dimerization interface [polypeptide binding]; other site
1132507001139	catalytic residues [active]
1132507001140	active site lid [active]
1132507001141	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1132507001142	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1132507001143	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507001144	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507001145	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1132507001146	dimerization interface [polypeptide binding]; other site
1132507001147	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1132507001148	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507001149	putative substrate translocation pore; other site
1132507001150	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1132507001151	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1132507001152	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1132507001153	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1132507001154	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1132507001155	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1132507001156	putative active site [active]
1132507001157	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1132507001158	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1132507001159	putative active site [active]
1132507001160	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1132507001161	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1132507001162	active site turn [active]
1132507001163	phosphorylation site [posttranslational modification]
1132507001164	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1132507001165	hypothetical protein; Provisional; Region: PRK11590
1132507001166	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1132507001167	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1132507001168	nucleoside/Zn binding site; other site
1132507001169	dimer interface [polypeptide binding]; other site
1132507001170	catalytic motif [active]
1132507001171	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1132507001172	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507001173	substrate binding pocket [chemical binding]; other site
1132507001174	membrane-bound complex binding site; other site
1132507001175	hinge residues; other site
1132507001176	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1132507001177	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1132507001178	catalytic residue [active]
1132507001179	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1132507001180	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1132507001181	dimerization interface [polypeptide binding]; other site
1132507001182	ATP binding site [chemical binding]; other site
1132507001183	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
1132507001184	dimerization interface [polypeptide binding]; other site
1132507001185	ATP binding site [chemical binding]; other site
1132507001186	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1132507001187	putative active site [active]
1132507001188	catalytic triad [active]
1132507001189	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1132507001190	HAMP domain; Region: HAMP; pfam00672
1132507001191	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507001192	dimer interface [polypeptide binding]; other site
1132507001193	phosphorylation site [posttranslational modification]
1132507001194	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507001195	ATP binding site [chemical binding]; other site
1132507001196	Mg2+ binding site [ion binding]; other site
1132507001197	G-X-G motif; other site
1132507001198	hypothetical protein; Provisional; Region: PRK10722
1132507001199	response regulator GlrR; Provisional; Region: PRK15115
1132507001200	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507001201	active site
1132507001202	phosphorylation site [posttranslational modification]
1132507001203	intermolecular recognition site; other site
1132507001204	dimerization interface [polypeptide binding]; other site
1132507001205	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507001206	Walker A motif; other site
1132507001207	ATP binding site [chemical binding]; other site
1132507001208	Walker B motif; other site
1132507001209	arginine finger; other site
1132507001210	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1132507001211	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1132507001212	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1132507001213	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507001214	putative substrate translocation pore; other site
1132507001215	POT family; Region: PTR2; pfam00854
1132507001216	lysine decarboxylase CadA; Provisional; Region: PRK15400
1132507001217	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1132507001218	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1132507001219	homodimer interface [polypeptide binding]; other site
1132507001220	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507001221	catalytic residue [active]
1132507001222	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1132507001223	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
1132507001224	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
1132507001225	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507001226	DNA binding site [nucleotide binding]
1132507001227	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1132507001228	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1132507001229	heme-binding site [chemical binding]; other site
1132507001230	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1132507001231	FAD binding pocket [chemical binding]; other site
1132507001232	FAD binding motif [chemical binding]; other site
1132507001233	phosphate binding motif [ion binding]; other site
1132507001234	beta-alpha-beta structure motif; other site
1132507001235	NAD binding pocket [chemical binding]; other site
1132507001236	Heme binding  pocket [chemical binding]; other site
1132507001237	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1132507001238	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1132507001239	dimer interface [polypeptide binding]; other site
1132507001240	active site
1132507001241	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1132507001242	folate binding site [chemical binding]; other site
1132507001243	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1132507001244	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507001245	putative substrate translocation pore; other site
1132507001246	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1132507001247	PRD domain; Region: PRD; pfam00874
1132507001248	PRD domain; Region: PRD; pfam00874
1132507001249	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
1132507001250	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
1132507001251	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1132507001252	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1132507001253	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
1132507001254	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
1132507001255	FAD binding pocket [chemical binding]; other site
1132507001256	FAD binding motif [chemical binding]; other site
1132507001257	phosphate binding motif [ion binding]; other site
1132507001258	beta-alpha-beta structure motif; other site
1132507001259	NAD binding pocket [chemical binding]; other site
1132507001260	Iron coordination center [ion binding]; other site
1132507001261	sulfite reductase, subunit A; Region: sulfite_red_A; TIGR02910
1132507001262	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1132507001263	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1132507001264	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1132507001265	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1132507001266	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1132507001267	active site
1132507001268	dimerization interface [polypeptide binding]; other site
1132507001269	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1132507001270	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1132507001271	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1132507001272	Rrf2 family protein; Region: rrf2_super; TIGR00738
1132507001273	cysteine desulfurase; Provisional; Region: PRK14012
1132507001274	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1132507001275	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1132507001276	catalytic residue [active]
1132507001277	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1132507001278	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1132507001279	trimerization site [polypeptide binding]; other site
1132507001280	active site
1132507001281	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1132507001282	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1132507001283	DnaJ domain; Region: DnaJ; pfam00226
1132507001284	HSP70 interaction site [polypeptide binding]; other site
1132507001285	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1132507001286	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1132507001287	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1132507001288	nucleotide binding site [chemical binding]; other site
1132507001289	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1132507001290	SBD interface [polypeptide binding]; other site
1132507001291	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1132507001292	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1132507001293	catalytic loop [active]
1132507001294	iron binding site [ion binding]; other site
1132507001295	hypothetical protein; Provisional; Region: PRK10721
1132507001296	aminopeptidase B; Provisional; Region: PRK05015
1132507001297	Peptidase; Region: DUF3663; pfam12404
1132507001298	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1132507001299	interface (dimer of trimers) [polypeptide binding]; other site
1132507001300	Substrate-binding/catalytic site; other site
1132507001301	Zn-binding sites [ion binding]; other site
1132507001302	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1132507001303	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1132507001304	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1132507001305	active site residue [active]
1132507001306	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1132507001307	active site residue [active]
1132507001308	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1132507001309	MG2 domain; Region: A2M_N; pfam01835
1132507001310	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1132507001311	surface patch; other site
1132507001312	thioester region; other site
1132507001313	specificity defining residues; other site
1132507001314	penicillin-binding protein 1C; Provisional; Region: PRK11240
1132507001315	Transglycosylase; Region: Transgly; pfam00912
1132507001316	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1132507001317	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1132507001318	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1132507001319	4Fe-4S binding domain; Region: Fer4; pfam00037
1132507001320	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1132507001321	4Fe-4S binding domain; Region: Fer4; pfam00037
1132507001322	hydrogenase 4 subunit H; Validated; Region: PRK08222
1132507001323	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1132507001324	active site
1132507001325	multimer interface [polypeptide binding]; other site
1132507001326	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1132507001327	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507001328	FeS/SAM binding site; other site
1132507001329	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1132507001330	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1132507001331	non-specific DNA binding site [nucleotide binding]; other site
1132507001332	salt bridge; other site
1132507001333	sequence-specific DNA binding site [nucleotide binding]; other site
1132507001334	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1132507001335	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1132507001336	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1132507001337	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1132507001338	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1132507001339	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1132507001340	dimer interface [polypeptide binding]; other site
1132507001341	motif 1; other site
1132507001342	active site
1132507001343	motif 2; other site
1132507001344	motif 3; other site
1132507001345	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1132507001346	anticodon binding site; other site
1132507001347	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1132507001348	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1132507001349	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1132507001350	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1132507001351	Trp docking motif [polypeptide binding]; other site
1132507001352	GTP-binding protein Der; Reviewed; Region: PRK00093
1132507001353	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1132507001354	G1 box; other site
1132507001355	GTP/Mg2+ binding site [chemical binding]; other site
1132507001356	Switch I region; other site
1132507001357	G2 box; other site
1132507001358	Switch II region; other site
1132507001359	G3 box; other site
1132507001360	G4 box; other site
1132507001361	G5 box; other site
1132507001362	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1132507001363	G1 box; other site
1132507001364	GTP/Mg2+ binding site [chemical binding]; other site
1132507001365	Switch I region; other site
1132507001366	G2 box; other site
1132507001367	G3 box; other site
1132507001368	Switch II region; other site
1132507001369	G4 box; other site
1132507001370	G5 box; other site
1132507001371	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1132507001372	intimin-like protein SinH; Provisional; Region: PRK15318
1132507001373	outer membrane protein RatA; Provisional; Region: PRK15315
1132507001374	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1132507001375	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1132507001376	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1132507001377	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1132507001378	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1132507001379	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1132507001380	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1132507001381	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1132507001382	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1132507001383	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1132507001384	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1132507001385	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1132507001386	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1132507001387	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1132507001388	generic binding surface II; other site
1132507001389	generic binding surface I; other site
1132507001390	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1132507001391	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1132507001392	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1132507001393	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1132507001394	active site
1132507001395	GMP synthase; Reviewed; Region: guaA; PRK00074
1132507001396	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1132507001397	AMP/PPi binding site [chemical binding]; other site
1132507001398	candidate oxyanion hole; other site
1132507001399	catalytic triad [active]
1132507001400	potential glutamine specificity residues [chemical binding]; other site
1132507001401	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1132507001402	ATP Binding subdomain [chemical binding]; other site
1132507001403	Ligand Binding sites [chemical binding]; other site
1132507001404	Dimerization subdomain; other site
1132507001405	GIY-YIG domain of uncharacterized proteins from bacteria and their eukaryotic homologs; Region: GIY-YIG_COG3680; cd10440
1132507001406	GIY-YIG motif/motif A; other site
1132507001407	putative active site [active]
1132507001408	putative metal binding site [ion binding]; other site
1132507001409	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
1132507001410	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1132507001411	MASE1; Region: MASE1; pfam05231
1132507001412	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1132507001413	diguanylate cyclase; Region: GGDEF; smart00267
1132507001414	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507001415	exopolyphosphatase; Provisional; Region: PRK10854
1132507001416	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1132507001417	nucleotide binding site [chemical binding]; other site
1132507001418	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1132507001419	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1132507001420	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1132507001421	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1132507001422	putative active site [active]
1132507001423	catalytic site [active]
1132507001424	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1132507001425	domain interface [polypeptide binding]; other site
1132507001426	active site
1132507001427	catalytic site [active]
1132507001428	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1132507001429	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1132507001430	active site
1132507001431	substrate binding site [chemical binding]; other site
1132507001432	cosubstrate binding site; other site
1132507001433	catalytic site [active]
1132507001434	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1132507001435	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1132507001436	dimerization interface [polypeptide binding]; other site
1132507001437	putative ATP binding site [chemical binding]; other site
1132507001438	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1132507001439	active site
1132507001440	uracil transporter; Provisional; Region: PRK10720
1132507001441	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1132507001442	DNA replication initiation factor; Provisional; Region: PRK08084
1132507001443	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1132507001444	ArsC family; Region: ArsC; pfam03960
1132507001445	catalytic residues [active]
1132507001446	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1132507001447	Peptidase family M48; Region: Peptidase_M48; cl12018
1132507001448	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1132507001449	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1132507001450	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1132507001451	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1132507001452	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1132507001453	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1132507001454	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1132507001455	catalytic triad [active]
1132507001456	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1132507001457	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1132507001458	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1132507001459	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1132507001460	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1132507001461	dimer interface [polypeptide binding]; other site
1132507001462	active site
1132507001463	catalytic residue [active]
1132507001464	lipoprotein; Provisional; Region: PRK11679
1132507001465	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1132507001466	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1132507001467	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1132507001468	ATP binding site [chemical binding]; other site
1132507001469	active site
1132507001470	substrate binding site [chemical binding]; other site
1132507001471	Predicted metalloprotease [General function prediction only]; Region: COG2321
1132507001472	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1132507001473	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1132507001474	Helicase; Region: Helicase_RecD; pfam05127
1132507001475	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507001476	Coenzyme A binding pocket [chemical binding]; other site
1132507001477	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1132507001478	hypothetical protein; Provisional; Region: PRK13664
1132507001479	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1132507001480	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1132507001481	metal binding site [ion binding]; metal-binding site
1132507001482	dimer interface [polypeptide binding]; other site
1132507001483	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1132507001484	ArsC family; Region: ArsC; pfam03960
1132507001485	putative catalytic residues [active]
1132507001486	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1132507001487	Protein export membrane protein; Region: SecD_SecF; cl14618
1132507001488	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1132507001489	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1132507001490	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507001491	dimerization interface [polypeptide binding]; other site
1132507001492	Histidine kinase; Region: HisKA_3; pfam07730
1132507001493	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507001494	ATP binding site [chemical binding]; other site
1132507001495	Mg2+ binding site [ion binding]; other site
1132507001496	G-X-G motif; other site
1132507001497	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1132507001498	4Fe-4S binding domain; Region: Fer4; pfam00037
1132507001499	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1132507001500	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507001501	putative periplasmic esterase; Provisional; Region: PRK03642
1132507001502	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1132507001503	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1132507001504	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1132507001505	dimer interface [polypeptide binding]; other site
1132507001506	ADP-ribose binding site [chemical binding]; other site
1132507001507	active site
1132507001508	nudix motif; other site
1132507001509	metal binding site [ion binding]; metal-binding site
1132507001510	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1132507001511	transketolase; Reviewed; Region: PRK12753
1132507001512	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1132507001513	TPP-binding site [chemical binding]; other site
1132507001514	dimer interface [polypeptide binding]; other site
1132507001515	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1132507001516	PYR/PP interface [polypeptide binding]; other site
1132507001517	dimer interface [polypeptide binding]; other site
1132507001518	TPP binding site [chemical binding]; other site
1132507001519	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1132507001520	transaldolase-like protein; Provisional; Region: PTZ00411
1132507001521	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1132507001522	active site
1132507001523	dimer interface [polypeptide binding]; other site
1132507001524	catalytic residue [active]
1132507001525	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1132507001526	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1132507001527	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1132507001528	putative NAD(P) binding site [chemical binding]; other site
1132507001529	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1132507001530	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507001531	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1132507001532	putative hexamer interface [polypeptide binding]; other site
1132507001533	putative hexagonal pore; other site
1132507001534	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1132507001535	G1 box; other site
1132507001536	GTP/Mg2+ binding site [chemical binding]; other site
1132507001537	G2 box; other site
1132507001538	Switch I region; other site
1132507001539	G3 box; other site
1132507001540	Switch II region; other site
1132507001541	G4 box; other site
1132507001542	G5 box; other site
1132507001543	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1132507001544	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
1132507001545	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
1132507001546	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1132507001547	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1132507001548	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1132507001549	Hexamer interface [polypeptide binding]; other site
1132507001550	Putative hexagonal pore residue; other site
1132507001551	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1132507001552	Hexamer/Pentamer interface [polypeptide binding]; other site
1132507001553	central pore; other site
1132507001554	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1132507001555	putative catalytic cysteine [active]
1132507001556	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
1132507001557	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1132507001558	nucleotide binding site [chemical binding]; other site
1132507001559	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
1132507001560	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1132507001561	active site
1132507001562	metal binding site [ion binding]; metal-binding site
1132507001563	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
1132507001564	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
1132507001565	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1132507001566	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1132507001567	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1132507001568	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1132507001569	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
1132507001570	putative hexamer interface [polypeptide binding]; other site
1132507001571	putative hexagonal pore; other site
1132507001572	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1132507001573	putative hexamer interface [polypeptide binding]; other site
1132507001574	putative hexagonal pore; other site
1132507001575	carboxysome structural protein EutK; Provisional; Region: PRK15466
1132507001576	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1132507001577	Hexamer interface [polypeptide binding]; other site
1132507001578	Hexagonal pore residue; other site
1132507001579	transcriptional regulator EutR; Provisional; Region: PRK10130
1132507001580	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507001581	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507001582	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1132507001583	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1132507001584	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1132507001585	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1132507001586	active site
1132507001587	metal binding site [ion binding]; metal-binding site
1132507001588	putative acetyltransferase; Provisional; Region: PRK03624
1132507001589	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507001590	Coenzyme A binding pocket [chemical binding]; other site
1132507001591	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1132507001592	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1132507001593	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1132507001594	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1132507001595	short chain dehydrogenase; Provisional; Region: PRK08226
1132507001596	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
1132507001597	NAD binding site [chemical binding]; other site
1132507001598	homotetramer interface [polypeptide binding]; other site
1132507001599	homodimer interface [polypeptide binding]; other site
1132507001600	active site
1132507001601	thiosulfate transporter subunit; Provisional; Region: PRK10852
1132507001602	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1132507001603	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1132507001604	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507001605	dimer interface [polypeptide binding]; other site
1132507001606	conserved gate region; other site
1132507001607	putative PBP binding loops; other site
1132507001608	ABC-ATPase subunit interface; other site
1132507001609	sulfate transport protein; Provisional; Region: cysT; CHL00187
1132507001610	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507001611	dimer interface [polypeptide binding]; other site
1132507001612	conserved gate region; other site
1132507001613	putative PBP binding loops; other site
1132507001614	ABC-ATPase subunit interface; other site
1132507001615	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1132507001616	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1132507001617	Walker A/P-loop; other site
1132507001618	ATP binding site [chemical binding]; other site
1132507001619	Q-loop/lid; other site
1132507001620	ABC transporter signature motif; other site
1132507001621	Walker B; other site
1132507001622	D-loop; other site
1132507001623	H-loop/switch region; other site
1132507001624	TOBE-like domain; Region: TOBE_3; pfam12857
1132507001625	cysteine synthase B; Region: cysM; TIGR01138
1132507001626	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1132507001627	dimer interface [polypeptide binding]; other site
1132507001628	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507001629	catalytic residue [active]
1132507001630	hypothetical protein; Provisional; Region: PRK10318
1132507001631	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1132507001632	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1132507001633	catalytic triad [active]
1132507001634	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
1132507001635	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507001636	DNA-binding site [nucleotide binding]; DNA binding site
1132507001637	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507001638	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507001639	homodimer interface [polypeptide binding]; other site
1132507001640	catalytic residue [active]
1132507001641	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1132507001642	dimer interface [polypeptide binding]; other site
1132507001643	pyridoxamine kinase; Validated; Region: PRK05756
1132507001644	pyridoxal binding site [chemical binding]; other site
1132507001645	ATP binding site [chemical binding]; other site
1132507001646	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1132507001647	HPr interaction site; other site
1132507001648	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1132507001649	active site
1132507001650	phosphorylation site [posttranslational modification]
1132507001651	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1132507001652	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1132507001653	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1132507001654	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1132507001655	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1132507001656	dimerization domain swap beta strand [polypeptide binding]; other site
1132507001657	regulatory protein interface [polypeptide binding]; other site
1132507001658	active site
1132507001659	regulatory phosphorylation site [posttranslational modification]; other site
1132507001660	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1132507001661	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1132507001662	dimer interface [polypeptide binding]; other site
1132507001663	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507001664	catalytic residue [active]
1132507001665	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1132507001666	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
1132507001667	cell division protein ZipA; Provisional; Region: PRK03427
1132507001668	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1132507001669	FtsZ protein binding site [polypeptide binding]; other site
1132507001670	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1132507001671	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1132507001672	nucleotide binding pocket [chemical binding]; other site
1132507001673	K-X-D-G motif; other site
1132507001674	catalytic site [active]
1132507001675	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1132507001676	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1132507001677	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1132507001678	Dimer interface [polypeptide binding]; other site
1132507001679	BRCT sequence motif; other site
1132507001680	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1132507001681	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1132507001682	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1132507001683	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507001684	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507001685	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1132507001686	putative dimerization interface [polypeptide binding]; other site
1132507001687	hypothetical protein; Provisional; Region: PRK11528
1132507001688	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1132507001689	nucleoside transporter; Region: 2A0110; TIGR00889
1132507001690	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507001691	putative substrate translocation pore; other site
1132507001692	XapX domain; Region: XapX; TIGR03510
1132507001693	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1132507001694	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507001695	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
1132507001696	putative dimerization interface [polypeptide binding]; other site
1132507001697	putative substrate binding pocket [chemical binding]; other site
1132507001698	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1132507001699	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1132507001700	active site
1132507001701	HIGH motif; other site
1132507001702	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1132507001703	active site
1132507001704	KMSKS motif; other site
1132507001705	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1132507001706	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1132507001707	MASE1; Region: MASE1; pfam05231
1132507001708	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1132507001709	diguanylate cyclase; Region: GGDEF; smart00267
1132507001710	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507001711	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1132507001712	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1132507001713	Nucleoside recognition; Region: Gate; pfam07670
1132507001714	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1132507001715	manganese transport protein MntH; Reviewed; Region: PRK00701
1132507001716	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1132507001717	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1132507001718	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1132507001719	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1132507001720	active site
1132507001721	catalytic tetrad [active]
1132507001722	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
1132507001723	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1132507001724	dimer interface [polypeptide binding]; other site
1132507001725	PYR/PP interface [polypeptide binding]; other site
1132507001726	TPP binding site [chemical binding]; other site
1132507001727	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1132507001728	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1132507001729	TPP-binding site [chemical binding]; other site
1132507001730	dimer interface [polypeptide binding]; other site
1132507001731	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1132507001732	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1132507001733	Cl- selectivity filter; other site
1132507001734	Cl- binding residues [ion binding]; other site
1132507001735	pore gating glutamate residue; other site
1132507001736	dimer interface [polypeptide binding]; other site
1132507001737	glucokinase; Provisional; Region: glk; PRK00292
1132507001738	glucokinase, proteobacterial type; Region: glk; TIGR00749
1132507001739	aminotransferase; Validated; Region: PRK08175
1132507001740	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507001741	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507001742	homodimer interface [polypeptide binding]; other site
1132507001743	catalytic residue [active]
1132507001744	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507001745	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1132507001746	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1132507001747	putative acyl-acceptor binding pocket; other site
1132507001748	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
1132507001749	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1132507001750	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507001751	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507001752	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1132507001753	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1132507001754	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
1132507001755	HAMP domain; Region: HAMP; pfam00672
1132507001756	dimerization interface [polypeptide binding]; other site
1132507001757	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507001758	dimer interface [polypeptide binding]; other site
1132507001759	phosphorylation site [posttranslational modification]
1132507001760	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507001761	ATP binding site [chemical binding]; other site
1132507001762	Mg2+ binding site [ion binding]; other site
1132507001763	G-X-G motif; other site
1132507001764	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1132507001765	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507001766	active site
1132507001767	phosphorylation site [posttranslational modification]
1132507001768	intermolecular recognition site; other site
1132507001769	dimerization interface [polypeptide binding]; other site
1132507001770	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1132507001771	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1132507001772	outer membrane protease; Reviewed; Region: PRK10993
1132507001773	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1132507001774	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1132507001775	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1132507001776	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1132507001777	active site
1132507001778	GtrA-like protein; Region: GtrA; pfam04138
1132507001779	Predicted membrane protein [Function unknown]; Region: COG2246
1132507001780	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1132507001781	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1132507001782	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1132507001783	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1132507001784	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1132507001785	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1132507001786	dimer interface [polypeptide binding]; other site
1132507001787	active site
1132507001788	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1132507001789	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1132507001790	substrate binding site [chemical binding]; other site
1132507001791	oxyanion hole (OAH) forming residues; other site
1132507001792	trimer interface [polypeptide binding]; other site
1132507001793	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1132507001794	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1132507001795	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1132507001796	catalytic core [active]
1132507001797	hypothetical protein; Provisional; Region: PRK04946
1132507001798	Smr domain; Region: Smr; pfam01713
1132507001799	HemK family putative methylases; Region: hemK_fam; TIGR00536
1132507001800	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507001801	S-adenosylmethionine binding site [chemical binding]; other site
1132507001802	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1132507001803	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1132507001804	Tetramer interface [polypeptide binding]; other site
1132507001805	active site
1132507001806	FMN-binding site [chemical binding]; other site
1132507001807	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1132507001808	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1132507001809	hypothetical protein; Provisional; Region: PRK10621
1132507001810	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1132507001811	YfcL protein; Region: YfcL; pfam08891
1132507001812	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1132507001813	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1132507001814	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1132507001815	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1132507001816	dimer interface [polypeptide binding]; other site
1132507001817	active site
1132507001818	CAAX protease self-immunity; Region: Abi; pfam02517
1132507001819	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1132507001820	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1132507001821	non-specific DNA binding site [nucleotide binding]; other site
1132507001822	salt bridge; other site
1132507001823	sequence-specific DNA binding site [nucleotide binding]; other site
1132507001824	putative transporter; Provisional; Region: PRK12382
1132507001825	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507001826	putative substrate translocation pore; other site
1132507001827	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1132507001828	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1132507001829	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1132507001830	ligand binding site [chemical binding]; other site
1132507001831	NAD binding site [chemical binding]; other site
1132507001832	catalytic site [active]
1132507001833	homodimer interface [polypeptide binding]; other site
1132507001834	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1132507001835	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1132507001836	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
1132507001837	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1132507001838	dimerization interface 3.5A [polypeptide binding]; other site
1132507001839	active site
1132507001840	hypothetical protein; Provisional; Region: PRK10847
1132507001841	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1132507001842	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1132507001843	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1132507001844	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1132507001845	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1132507001846	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1132507001847	cell division protein DedD; Provisional; Region: PRK11633
1132507001848	Sporulation related domain; Region: SPOR; pfam05036
1132507001849	colicin V production protein; Provisional; Region: PRK10845
1132507001850	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1132507001851	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1132507001852	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1132507001853	active site
1132507001854	tetramer interface [polypeptide binding]; other site
1132507001855	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1132507001856	active site
1132507001857	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1132507001858	PAS fold; Region: PAS_4; pfam08448
1132507001859	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1132507001860	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507001861	Walker A motif; other site
1132507001862	ATP binding site [chemical binding]; other site
1132507001863	Walker B motif; other site
1132507001864	arginine finger; other site
1132507001865	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1132507001866	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1132507001867	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1132507001868	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1132507001869	catalytic residue [active]
1132507001870	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
1132507001871	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
1132507001872	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
1132507001873	dimer interface [polypeptide binding]; other site
1132507001874	active site
1132507001875	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1132507001876	substrate binding site [chemical binding]; other site
1132507001877	catalytic residue [active]
1132507001878	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1132507001879	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1132507001880	Flavoprotein; Region: Flavoprotein; pfam02441
1132507001881	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1132507001882	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507001883	substrate binding pocket [chemical binding]; other site
1132507001884	membrane-bound complex binding site; other site
1132507001885	hinge residues; other site
1132507001886	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1132507001887	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507001888	substrate binding pocket [chemical binding]; other site
1132507001889	membrane-bound complex binding site; other site
1132507001890	hinge residues; other site
1132507001891	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1132507001892	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507001893	dimer interface [polypeptide binding]; other site
1132507001894	conserved gate region; other site
1132507001895	putative PBP binding loops; other site
1132507001896	ABC-ATPase subunit interface; other site
1132507001897	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1132507001898	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507001899	dimer interface [polypeptide binding]; other site
1132507001900	conserved gate region; other site
1132507001901	putative PBP binding loops; other site
1132507001902	ABC-ATPase subunit interface; other site
1132507001903	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1132507001904	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1132507001905	Walker A/P-loop; other site
1132507001906	ATP binding site [chemical binding]; other site
1132507001907	Q-loop/lid; other site
1132507001908	ABC transporter signature motif; other site
1132507001909	Walker B; other site
1132507001910	D-loop; other site
1132507001911	H-loop/switch region; other site
1132507001912	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1132507001913	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1132507001914	putative NAD(P) binding site [chemical binding]; other site
1132507001915	putative active site [active]
1132507001916	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1132507001917	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1132507001918	C-terminal domain interface [polypeptide binding]; other site
1132507001919	GSH binding site (G-site) [chemical binding]; other site
1132507001920	dimer interface [polypeptide binding]; other site
1132507001921	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1132507001922	N-terminal domain interface [polypeptide binding]; other site
1132507001923	putative dimer interface [polypeptide binding]; other site
1132507001924	active site
1132507001925	glutathione S-transferase; Provisional; Region: PRK15113
1132507001926	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1132507001927	C-terminal domain interface [polypeptide binding]; other site
1132507001928	GSH binding site (G-site) [chemical binding]; other site
1132507001929	dimer interface [polypeptide binding]; other site
1132507001930	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1132507001931	N-terminal domain interface [polypeptide binding]; other site
1132507001932	putative dimer interface [polypeptide binding]; other site
1132507001933	putative substrate binding pocket (H-site) [chemical binding]; other site
1132507001934	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1132507001935	active site
1132507001936	metal binding site [ion binding]; metal-binding site
1132507001937	homotetramer interface [polypeptide binding]; other site
1132507001938	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1132507001939	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1132507001940	nudix motif; other site
1132507001941	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1132507001942	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507001943	DNA binding site [nucleotide binding]
1132507001944	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1132507001945	putative dimerization interface [polypeptide binding]; other site
1132507001946	putative ligand binding site [chemical binding]; other site
1132507001947	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1132507001948	active site
1132507001949	phosphorylation site [posttranslational modification]
1132507001950	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1132507001951	active site
1132507001952	P-loop; other site
1132507001953	phosphorylation site [posttranslational modification]
1132507001954	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
1132507001955	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1132507001956	TPP-binding site [chemical binding]; other site
1132507001957	dimer interface [polypeptide binding]; other site
1132507001958	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1132507001959	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1132507001960	PYR/PP interface [polypeptide binding]; other site
1132507001961	dimer interface [polypeptide binding]; other site
1132507001962	TPP binding site [chemical binding]; other site
1132507001963	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1132507001964	hypothetical protein; Provisional; Region: PRK11588
1132507001965	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1132507001966	phosphate acetyltransferase; Reviewed; Region: PRK05632
1132507001967	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1132507001968	DRTGG domain; Region: DRTGG; pfam07085
1132507001969	phosphate acetyltransferase; Region: pta; TIGR00651
1132507001970	propionate/acetate kinase; Provisional; Region: PRK12379
1132507001971	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1132507001972	hypothetical protein; Provisional; Region: PRK01816
1132507001973	hypothetical protein; Validated; Region: PRK05445
1132507001974	putative phosphatase; Provisional; Region: PRK11587
1132507001975	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507001976	motif II; other site
1132507001977	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1132507001978	transmembrane helices; other site
1132507001979	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1132507001980	TrkA-C domain; Region: TrkA_C; pfam02080
1132507001981	TrkA-C domain; Region: TrkA_C; pfam02080
1132507001982	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1132507001983	5'-nucleotidase; Provisional; Region: PRK03826
1132507001984	aminotransferase AlaT; Validated; Region: PRK09265
1132507001985	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507001986	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507001987	homodimer interface [polypeptide binding]; other site
1132507001988	catalytic residue [active]
1132507001989	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1132507001990	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507001991	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1132507001992	putative dimerization interface [polypeptide binding]; other site
1132507001993	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1132507001994	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1132507001995	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1132507001996	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1132507001997	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1132507001998	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1132507001999	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1132507002000	putative dimer interface [polypeptide binding]; other site
1132507002001	[2Fe-2S] cluster binding site [ion binding]; other site
1132507002002	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1132507002003	SLBB domain; Region: SLBB; pfam10531
1132507002004	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1132507002005	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1132507002006	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1132507002007	catalytic loop [active]
1132507002008	iron binding site [ion binding]; other site
1132507002009	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1132507002010	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1132507002011	[4Fe-4S] binding site [ion binding]; other site
1132507002012	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1132507002013	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1132507002014	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1132507002015	4Fe-4S binding domain; Region: Fer4; pfam00037
1132507002016	4Fe-4S binding domain; Region: Fer4; pfam00037
1132507002017	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1132507002018	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1132507002019	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1132507002020	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1132507002021	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1132507002022	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1132507002023	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1132507002024	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1132507002025	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1132507002026	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1132507002027	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1132507002028	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1132507002029	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507002030	active site
1132507002031	phosphorylation site [posttranslational modification]
1132507002032	intermolecular recognition site; other site
1132507002033	dimerization interface [polypeptide binding]; other site
1132507002034	ribonuclease BN; Region: true_RNase_BN; TIGR02649
1132507002035	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507002036	Coenzyme A binding pocket [chemical binding]; other site
1132507002037	hypothetical protein; Provisional; Region: PRK10404
1132507002038	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1132507002039	isochorismate synthases; Region: isochor_syn; TIGR00543
1132507002040	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1132507002041	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1132507002042	dimer interface [polypeptide binding]; other site
1132507002043	tetramer interface [polypeptide binding]; other site
1132507002044	PYR/PP interface [polypeptide binding]; other site
1132507002045	TPP binding site [chemical binding]; other site
1132507002046	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1132507002047	TPP-binding site; other site
1132507002048	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1132507002049	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1132507002050	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1132507002051	substrate binding site [chemical binding]; other site
1132507002052	oxyanion hole (OAH) forming residues; other site
1132507002053	trimer interface [polypeptide binding]; other site
1132507002054	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
1132507002055	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1132507002056	active site
1132507002057	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1132507002058	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1132507002059	acyl-activating enzyme (AAE) consensus motif; other site
1132507002060	putative AMP binding site [chemical binding]; other site
1132507002061	putative active site [active]
1132507002062	putative CoA binding site [chemical binding]; other site
1132507002063	signal transduction protein PmrD; Provisional; Region: PRK15450
1132507002064	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1132507002065	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1132507002066	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1132507002067	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1132507002068	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1132507002069	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1132507002070	putative active site [active]
1132507002071	putative catalytic site [active]
1132507002072	putative Zn binding site [ion binding]; other site
1132507002073	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1132507002074	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1132507002075	active site
1132507002076	substrate binding site [chemical binding]; other site
1132507002077	cosubstrate binding site; other site
1132507002078	catalytic site [active]
1132507002079	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1132507002080	active site
1132507002081	hexamer interface [polypeptide binding]; other site
1132507002082	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1132507002083	NAD binding site [chemical binding]; other site
1132507002084	substrate binding site [chemical binding]; other site
1132507002085	active site
1132507002086	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1132507002087	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1132507002088	Ligand binding site; other site
1132507002089	Putative Catalytic site; other site
1132507002090	DXD motif; other site
1132507002091	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1132507002092	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1132507002093	inhibitor-cofactor binding pocket; inhibition site
1132507002094	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507002095	catalytic residue [active]
1132507002096	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1132507002097	catalytic core [active]
1132507002098	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1132507002099	YfaZ precursor; Region: YfaZ; pfam07437
1132507002100	hypothetical protein; Provisional; Region: PRK03673
1132507002101	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1132507002102	putative MPT binding site; other site
1132507002103	Competence-damaged protein; Region: CinA; cl00666
1132507002104	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1132507002105	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1132507002106	Bacterial transcriptional regulator; Region: IclR; pfam01614
1132507002107	L-rhamnonate dehydratase; Provisional; Region: PRK15440
1132507002108	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
1132507002109	putative active site pocket [active]
1132507002110	putative metal binding site [ion binding]; other site
1132507002111	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507002112	D-galactonate transporter; Region: 2A0114; TIGR00893
1132507002113	putative substrate translocation pore; other site
1132507002114	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
1132507002115	Competence-damaged protein; Region: CinA; cl00666
1132507002116	deubiquitinase SseL; Provisional; Region: PRK14848
1132507002117	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1132507002118	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1132507002119	Cysteine-rich domain; Region: CCG; pfam02754
1132507002120	Cysteine-rich domain; Region: CCG; pfam02754
1132507002121	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1132507002122	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1132507002123	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1132507002124	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1132507002125	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1132507002126	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1132507002127	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507002128	putative substrate translocation pore; other site
1132507002129	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1132507002130	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1132507002131	active site
1132507002132	catalytic site [active]
1132507002133	metal binding site [ion binding]; metal-binding site
1132507002134	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
1132507002135	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507002136	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1132507002137	dimerization interface [polypeptide binding]; other site
1132507002138	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1132507002139	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507002140	putative substrate translocation pore; other site
1132507002141	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1132507002142	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1132507002143	catalytic loop [active]
1132507002144	iron binding site [ion binding]; other site
1132507002145	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1132507002146	dimer interface [polypeptide binding]; other site
1132507002147	putative radical transfer pathway; other site
1132507002148	diiron center [ion binding]; other site
1132507002149	tyrosyl radical; other site
1132507002150	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1132507002151	ATP cone domain; Region: ATP-cone; pfam03477
1132507002152	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1132507002153	active site
1132507002154	dimer interface [polypeptide binding]; other site
1132507002155	catalytic residues [active]
1132507002156	effector binding site; other site
1132507002157	R2 peptide binding site; other site
1132507002158	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1132507002159	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507002160	S-adenosylmethionine binding site [chemical binding]; other site
1132507002161	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1132507002162	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507002163	DNA-binding site [nucleotide binding]; DNA binding site
1132507002164	FCD domain; Region: FCD; pfam07729
1132507002165	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1132507002166	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1132507002167	active site pocket [active]
1132507002168	DNA gyrase subunit A; Validated; Region: PRK05560
1132507002169	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1132507002170	CAP-like domain; other site
1132507002171	active site
1132507002172	primary dimer interface [polypeptide binding]; other site
1132507002173	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1132507002174	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1132507002175	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1132507002176	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1132507002177	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1132507002178	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1132507002179	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507002180	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1132507002181	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507002182	dimer interface [polypeptide binding]; other site
1132507002183	phosphorylation site [posttranslational modification]
1132507002184	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507002185	ATP binding site [chemical binding]; other site
1132507002186	Mg2+ binding site [ion binding]; other site
1132507002187	G-X-G motif; other site
1132507002188	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1132507002189	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507002190	active site
1132507002191	phosphorylation site [posttranslational modification]
1132507002192	intermolecular recognition site; other site
1132507002193	dimerization interface [polypeptide binding]; other site
1132507002194	transcriptional regulator RcsB; Provisional; Region: PRK10840
1132507002195	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507002196	active site
1132507002197	phosphorylation site [posttranslational modification]
1132507002198	intermolecular recognition site; other site
1132507002199	dimerization interface [polypeptide binding]; other site
1132507002200	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507002201	DNA binding residues [nucleotide binding]
1132507002202	dimerization interface [polypeptide binding]; other site
1132507002203	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1132507002204	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507002205	ATP binding site [chemical binding]; other site
1132507002206	G-X-G motif; other site
1132507002207	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1132507002208	putative binding surface; other site
1132507002209	active site
1132507002210	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1132507002211	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1132507002212	trimer interface [polypeptide binding]; other site
1132507002213	eyelet of channel; other site
1132507002214	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1132507002215	ApbE family; Region: ApbE; pfam02424
1132507002216	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1132507002217	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1132507002218	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507002219	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1132507002220	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1132507002221	DNA binding site [nucleotide binding]
1132507002222	active site
1132507002223	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1132507002224	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1132507002225	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1132507002226	Walker A/P-loop; other site
1132507002227	ATP binding site [chemical binding]; other site
1132507002228	Q-loop/lid; other site
1132507002229	ABC transporter signature motif; other site
1132507002230	Walker B; other site
1132507002231	D-loop; other site
1132507002232	H-loop/switch region; other site
1132507002233	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1132507002234	secondary substrate binding site; other site
1132507002235	primary substrate binding site; other site
1132507002236	inhibition loop; other site
1132507002237	dimerization interface [polypeptide binding]; other site
1132507002238	ferredoxin-type protein; Provisional; Region: PRK10194
1132507002239	4Fe-4S binding domain; Region: Fer4; cl02805
1132507002240	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
1132507002241	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1132507002242	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1132507002243	[4Fe-4S] binding site [ion binding]; other site
1132507002244	molybdopterin cofactor binding site; other site
1132507002245	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1132507002246	molybdopterin cofactor binding site; other site
1132507002247	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1132507002248	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1132507002249	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1132507002250	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1132507002251	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
1132507002252	cytochrome c-type protein NapC; Provisional; Region: PRK10617
1132507002253	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1132507002254	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507002255	Walker A/P-loop; other site
1132507002256	ATP binding site [chemical binding]; other site
1132507002257	Q-loop/lid; other site
1132507002258	ABC transporter signature motif; other site
1132507002259	Walker B; other site
1132507002260	D-loop; other site
1132507002261	H-loop/switch region; other site
1132507002262	heme exporter protein CcmB; Region: ccmB; TIGR01190
1132507002263	heme exporter protein CcmC; Region: ccmC; TIGR01191
1132507002264	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1132507002265	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1132507002266	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1132507002267	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1132507002268	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1132507002269	catalytic residues [active]
1132507002270	central insert; other site
1132507002271	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1132507002272	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1132507002273	transcriptional regulator NarP; Provisional; Region: PRK10403
1132507002274	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507002275	active site
1132507002276	phosphorylation site [posttranslational modification]
1132507002277	intermolecular recognition site; other site
1132507002278	dimerization interface [polypeptide binding]; other site
1132507002279	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507002280	DNA binding residues [nucleotide binding]
1132507002281	dimerization interface [polypeptide binding]; other site
1132507002282	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
1132507002283	DinI-like family; Region: DinI; cl11630
1132507002284	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1132507002285	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
1132507002286	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
1132507002287	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
1132507002288	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1132507002289	Leucine-rich repeats; other site
1132507002290	Substrate binding site [chemical binding]; other site
1132507002291	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1132507002292	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1132507002293	Sulfatase; Region: Sulfatase; cl17466
1132507002294	hypothetical protein; Provisional; Region: PRK13689
1132507002295	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1132507002296	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1132507002297	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1132507002298	5S rRNA interface [nucleotide binding]; other site
1132507002299	CTC domain interface [polypeptide binding]; other site
1132507002300	L16 interface [polypeptide binding]; other site
1132507002301	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1132507002302	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507002303	ATP binding site [chemical binding]; other site
1132507002304	putative Mg++ binding site [ion binding]; other site
1132507002305	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507002306	nucleotide binding region [chemical binding]; other site
1132507002307	ATP-binding site [chemical binding]; other site
1132507002308	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1132507002309	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1132507002310	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1132507002311	RNA binding surface [nucleotide binding]; other site
1132507002312	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1132507002313	active site
1132507002314	uracil binding [chemical binding]; other site
1132507002315	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507002316	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1132507002317	putative substrate translocation pore; other site
1132507002318	hypothetical protein; Provisional; Region: PRK11835
1132507002319	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1132507002320	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507002321	Walker A/P-loop; other site
1132507002322	ATP binding site [chemical binding]; other site
1132507002323	Q-loop/lid; other site
1132507002324	ABC transporter signature motif; other site
1132507002325	Walker B; other site
1132507002326	D-loop; other site
1132507002327	H-loop/switch region; other site
1132507002328	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1132507002329	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507002330	Walker A/P-loop; other site
1132507002331	ATP binding site [chemical binding]; other site
1132507002332	Q-loop/lid; other site
1132507002333	ABC transporter signature motif; other site
1132507002334	Walker B; other site
1132507002335	D-loop; other site
1132507002336	H-loop/switch region; other site
1132507002337	microcin C ABC transporter permease; Provisional; Region: PRK15021
1132507002338	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507002339	dimer interface [polypeptide binding]; other site
1132507002340	conserved gate region; other site
1132507002341	ABC-ATPase subunit interface; other site
1132507002342	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1132507002343	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507002344	dimer interface [polypeptide binding]; other site
1132507002345	conserved gate region; other site
1132507002346	putative PBP binding loops; other site
1132507002347	ABC-ATPase subunit interface; other site
1132507002348	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1132507002349	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1132507002350	phage resistance protein; Provisional; Region: PRK10551
1132507002351	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1132507002352	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507002353	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1132507002354	NlpC/P60 family; Region: NLPC_P60; pfam00877
1132507002355	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1132507002356	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1132507002357	active site
1132507002358	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1132507002359	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1132507002360	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1132507002361	elongation factor P; Provisional; Region: PRK04542
1132507002362	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1132507002363	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1132507002364	RNA binding site [nucleotide binding]; other site
1132507002365	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1132507002366	RNA binding site [nucleotide binding]; other site
1132507002367	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1132507002368	sugar efflux transporter B; Provisional; Region: PRK15011
1132507002369	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507002370	putative substrate translocation pore; other site
1132507002371	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1132507002372	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1132507002373	active site
1132507002374	phosphorylation site [posttranslational modification]
1132507002375	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1132507002376	dimerization domain swap beta strand [polypeptide binding]; other site
1132507002377	regulatory protein interface [polypeptide binding]; other site
1132507002378	active site
1132507002379	regulatory phosphorylation site [posttranslational modification]; other site
1132507002380	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1132507002381	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1132507002382	putative substrate binding site [chemical binding]; other site
1132507002383	putative ATP binding site [chemical binding]; other site
1132507002384	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1132507002385	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1132507002386	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1132507002387	active site
1132507002388	P-loop; other site
1132507002389	phosphorylation site [posttranslational modification]
1132507002390	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1132507002391	endonuclease IV; Provisional; Region: PRK01060
1132507002392	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1132507002393	AP (apurinic/apyrimidinic) site pocket; other site
1132507002394	DNA interaction; other site
1132507002395	Metal-binding active site; metal-binding site
1132507002396	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1132507002397	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1132507002398	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507002399	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1132507002400	putative dimerization interface [polypeptide binding]; other site
1132507002401	lysine transporter; Provisional; Region: PRK10836
1132507002402	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
1132507002403	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1132507002404	N-terminal plug; other site
1132507002405	ligand-binding site [chemical binding]; other site
1132507002406	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1132507002407	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1132507002408	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507002409	putative substrate translocation pore; other site
1132507002410	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1132507002411	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1132507002412	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507002413	motif II; other site
1132507002414	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1132507002415	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1132507002416	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1132507002417	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1132507002418	non-specific DNA binding site [nucleotide binding]; other site
1132507002419	salt bridge; other site
1132507002420	sequence-specific DNA binding site [nucleotide binding]; other site
1132507002421	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1132507002422	S-formylglutathione hydrolase; Region: PLN02442
1132507002423	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1132507002424	GTP cyclohydrolase I; Provisional; Region: PLN03044
1132507002425	active site
1132507002426	Predicted membrane protein [Function unknown]; Region: COG2311
1132507002427	hypothetical protein; Provisional; Region: PRK10835
1132507002428	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1132507002429	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507002430	DNA binding site [nucleotide binding]
1132507002431	domain linker motif; other site
1132507002432	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1132507002433	dimerization interface (closed form) [polypeptide binding]; other site
1132507002434	ligand binding site [chemical binding]; other site
1132507002435	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1132507002436	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1132507002437	ligand binding site [chemical binding]; other site
1132507002438	calcium binding site [ion binding]; other site
1132507002439	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1132507002440	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1132507002441	TM-ABC transporter signature motif; other site
1132507002442	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1132507002443	phosphate binding site [ion binding]; other site
1132507002444	Ferredoxin [Energy production and conversion]; Region: COG1146
1132507002445	4Fe-4S binding domain; Region: Fer4; cl02805
1132507002446	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1132507002447	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1132507002448	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1132507002449	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507002450	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
1132507002451	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1132507002452	putative active site [active]
1132507002453	cytidine deaminase; Provisional; Region: PRK09027
1132507002454	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1132507002455	active site
1132507002456	catalytic motif [active]
1132507002457	Zn binding site [ion binding]; other site
1132507002458	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1132507002459	active site
1132507002460	catalytic motif [active]
1132507002461	Zn binding site [ion binding]; other site
1132507002462	hypothetical protein; Provisional; Region: PRK10711
1132507002463	hypothetical protein; Provisional; Region: PRK01821
1132507002464	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1132507002465	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507002466	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507002467	dimerization interface [polypeptide binding]; other site
1132507002468	benzoate transport; Region: 2A0115; TIGR00895
1132507002469	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507002470	putative substrate translocation pore; other site
1132507002471	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
1132507002472	Cupin domain; Region: Cupin_2; pfam07883
1132507002473	Cupin domain; Region: Cupin_2; pfam07883
1132507002474	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1132507002475	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1132507002476	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
1132507002477	maleylacetoacetate isomerase; Region: maiA; TIGR01262
1132507002478	C-terminal domain interface [polypeptide binding]; other site
1132507002479	GSH binding site (G-site) [chemical binding]; other site
1132507002480	putative dimer interface [polypeptide binding]; other site
1132507002481	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
1132507002482	dimer interface [polypeptide binding]; other site
1132507002483	N-terminal domain interface [polypeptide binding]; other site
1132507002484	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
1132507002485	salicylate hydroxylase; Provisional; Region: PRK08163
1132507002486	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1132507002487	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1132507002488	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1132507002489	FMN binding site [chemical binding]; other site
1132507002490	active site
1132507002491	catalytic residues [active]
1132507002492	substrate binding site [chemical binding]; other site
1132507002493	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
1132507002494	oxidoreductase; Provisional; Region: PRK12743
1132507002495	classical (c) SDRs; Region: SDR_c; cd05233
1132507002496	NAD(P) binding site [chemical binding]; other site
1132507002497	active site
1132507002498	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1132507002499	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1132507002500	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1132507002501	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1132507002502	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1132507002503	D-lactate dehydrogenase; Provisional; Region: PRK11183
1132507002504	FAD binding domain; Region: FAD_binding_4; pfam01565
1132507002505	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1132507002506	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1132507002507	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1132507002508	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1132507002509	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1132507002510	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507002511	dimer interface [polypeptide binding]; other site
1132507002512	conserved gate region; other site
1132507002513	ABC-ATPase subunit interface; other site
1132507002514	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1132507002515	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1132507002516	Walker A/P-loop; other site
1132507002517	ATP binding site [chemical binding]; other site
1132507002518	Q-loop/lid; other site
1132507002519	ABC transporter signature motif; other site
1132507002520	Walker B; other site
1132507002521	D-loop; other site
1132507002522	H-loop/switch region; other site
1132507002523	CBS domain; Region: CBS; pfam00571
1132507002524	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
1132507002525	transcriptional regulator MirA; Provisional; Region: PRK15043
1132507002526	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
1132507002527	DNA binding residues [nucleotide binding]
1132507002528	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1132507002529	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1132507002530	GAF domain; Region: GAF; pfam01590
1132507002531	Histidine kinase; Region: His_kinase; pfam06580
1132507002532	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507002533	ATP binding site [chemical binding]; other site
1132507002534	Mg2+ binding site [ion binding]; other site
1132507002535	G-X-G motif; other site
1132507002536	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1132507002537	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507002538	active site
1132507002539	phosphorylation site [posttranslational modification]
1132507002540	intermolecular recognition site; other site
1132507002541	dimerization interface [polypeptide binding]; other site
1132507002542	LytTr DNA-binding domain; Region: LytTR; pfam04397
1132507002543	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1132507002544	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1132507002545	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1132507002546	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1132507002547	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1132507002548	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1132507002549	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1132507002550	active site
1132507002551	HIGH motif; other site
1132507002552	KMSKS motif; other site
1132507002553	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1132507002554	tRNA binding surface [nucleotide binding]; other site
1132507002555	anticodon binding site; other site
1132507002556	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1132507002557	dimer interface [polypeptide binding]; other site
1132507002558	putative tRNA-binding site [nucleotide binding]; other site
1132507002559	antiporter inner membrane protein; Provisional; Region: PRK11670
1132507002560	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1132507002561	Walker A motif; other site
1132507002562	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
1132507002563	fimbrial chaperone protein; Provisional; Region: PRK15220
1132507002564	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
1132507002565	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507002566	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507002567	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
1132507002568	PapC N-terminal domain; Region: PapC_N; pfam13954
1132507002569	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1132507002570	PapC C-terminal domain; Region: PapC_C; pfam13953
1132507002571	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
1132507002572	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
1132507002573	Predicted integral membrane protein [Function unknown]; Region: COG5455
1132507002574	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1132507002575	substrate binding site [chemical binding]; other site
1132507002576	multimerization interface [polypeptide binding]; other site
1132507002577	ATP binding site [chemical binding]; other site
1132507002578	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1132507002579	dimer interface [polypeptide binding]; other site
1132507002580	substrate binding site [chemical binding]; other site
1132507002581	ATP binding site [chemical binding]; other site
1132507002582	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1132507002583	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507002584	DNA-binding site [nucleotide binding]; DNA binding site
1132507002585	UTRA domain; Region: UTRA; pfam07702
1132507002586	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1132507002587	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1132507002588	substrate binding site [chemical binding]; other site
1132507002589	ATP binding site [chemical binding]; other site
1132507002590	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1132507002591	nucleoside transporter; Region: 2A0110; TIGR00889
1132507002592	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507002593	putative substrate translocation pore; other site
1132507002594	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1132507002595	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1132507002596	putative active site; other site
1132507002597	catalytic residue [active]
1132507002598	lipid kinase; Reviewed; Region: PRK13054
1132507002599	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1132507002600	Tir chaperone protein (CesT) family; Region: CesT; cl08444
1132507002601	putative protease; Provisional; Region: PRK15452
1132507002602	Peptidase family U32; Region: Peptidase_U32; pfam01136
1132507002603	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
1132507002604	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1132507002605	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
1132507002606	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1132507002607	PcfJ-like protein; Region: PcfJ; pfam14284
1132507002608	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1132507002609	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507002610	active site
1132507002611	phosphorylation site [posttranslational modification]
1132507002612	intermolecular recognition site; other site
1132507002613	dimerization interface [polypeptide binding]; other site
1132507002614	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507002615	DNA binding site [nucleotide binding]
1132507002616	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1132507002617	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507002618	dimerization interface [polypeptide binding]; other site
1132507002619	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507002620	dimer interface [polypeptide binding]; other site
1132507002621	phosphorylation site [posttranslational modification]
1132507002622	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507002623	ATP binding site [chemical binding]; other site
1132507002624	Mg2+ binding site [ion binding]; other site
1132507002625	G-X-G motif; other site
1132507002626	putative transporter; Provisional; Region: PRK10504
1132507002627	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507002628	putative substrate translocation pore; other site
1132507002629	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1132507002630	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1132507002631	Protein export membrane protein; Region: SecD_SecF; cl14618
1132507002632	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1132507002633	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1132507002634	HlyD family secretion protein; Region: HlyD_3; pfam13437
1132507002635	putative chaperone; Provisional; Region: PRK11678
1132507002636	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1132507002637	nucleotide binding site [chemical binding]; other site
1132507002638	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1132507002639	SBD interface [polypeptide binding]; other site
1132507002640	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1132507002641	AlkA N-terminal domain; Region: AlkA_N; pfam06029
1132507002642	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1132507002643	minor groove reading motif; other site
1132507002644	helix-hairpin-helix signature motif; other site
1132507002645	substrate binding pocket [chemical binding]; other site
1132507002646	active site
1132507002647	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
1132507002648	PAS domain S-box; Region: sensory_box; TIGR00229
1132507002649	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1132507002650	putative active site [active]
1132507002651	heme pocket [chemical binding]; other site
1132507002652	PAS domain S-box; Region: sensory_box; TIGR00229
1132507002653	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1132507002654	putative active site [active]
1132507002655	heme pocket [chemical binding]; other site
1132507002656	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1132507002657	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507002658	metal binding site [ion binding]; metal-binding site
1132507002659	active site
1132507002660	I-site; other site
1132507002661	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507002662	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1132507002663	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1132507002664	ATP-binding site [chemical binding]; other site
1132507002665	Sugar specificity; other site
1132507002666	Pyrimidine base specificity; other site
1132507002667	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1132507002668	trimer interface [polypeptide binding]; other site
1132507002669	active site
1132507002670	putative assembly protein; Provisional; Region: PRK10833
1132507002671	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1132507002672	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1132507002673	FOG: CBS domain [General function prediction only]; Region: COG0517
1132507002674	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1132507002675	Transporter associated domain; Region: CorC_HlyC; smart01091
1132507002676	polysaccharide export protein Wza; Provisional; Region: PRK15078
1132507002677	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1132507002678	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1132507002679	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1132507002680	active site
1132507002681	tyrosine kinase; Provisional; Region: PRK11519
1132507002682	Chain length determinant protein; Region: Wzz; pfam02706
1132507002683	Chain length determinant protein; Region: Wzz; cl15801
1132507002684	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1132507002685	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1132507002686	putative glycosyl transferase; Provisional; Region: PRK10018
1132507002687	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1132507002688	active site
1132507002689	putative acyl transferase; Provisional; Region: PRK10191
1132507002690	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1132507002691	trimer interface [polypeptide binding]; other site
1132507002692	active site
1132507002693	substrate binding site [chemical binding]; other site
1132507002694	CoA binding site [chemical binding]; other site
1132507002695	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
1132507002696	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1132507002697	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1132507002698	putative glycosyl transferase; Provisional; Region: PRK10063
1132507002699	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1132507002700	metal-binding site
1132507002701	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
1132507002702	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1132507002703	putative trimer interface [polypeptide binding]; other site
1132507002704	putative active site [active]
1132507002705	putative substrate binding site [chemical binding]; other site
1132507002706	putative CoA binding site [chemical binding]; other site
1132507002707	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1132507002708	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1132507002709	NADP-binding site; other site
1132507002710	homotetramer interface [polypeptide binding]; other site
1132507002711	substrate binding site [chemical binding]; other site
1132507002712	homodimer interface [polypeptide binding]; other site
1132507002713	active site
1132507002714	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1132507002715	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1132507002716	NADP binding site [chemical binding]; other site
1132507002717	active site
1132507002718	putative substrate binding site [chemical binding]; other site
1132507002719	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1132507002720	active site
1132507002721	GDP-Mannose binding site [chemical binding]; other site
1132507002722	dimer interface [polypeptide binding]; other site
1132507002723	modified nudix motif
1132507002724	metal binding site [ion binding]; metal-binding site
1132507002725	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
1132507002726	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1132507002727	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
1132507002728	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1132507002729	Substrate binding site; other site
1132507002730	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1132507002731	phosphomannomutase CpsG; Provisional; Region: PRK15414
1132507002732	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1132507002733	active site
1132507002734	substrate binding site [chemical binding]; other site
1132507002735	metal binding site [ion binding]; metal-binding site
1132507002736	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
1132507002737	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
1132507002738	colanic acid exporter; Provisional; Region: PRK10459
1132507002739	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1132507002740	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
1132507002741	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1132507002742	putative ADP-binding pocket [chemical binding]; other site
1132507002743	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
1132507002744	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1132507002745	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1132507002746	active site
1132507002747	tetramer interface; other site
1132507002748	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
1132507002749	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1132507002750	NAD binding site [chemical binding]; other site
1132507002751	substrate binding site [chemical binding]; other site
1132507002752	homodimer interface [polypeptide binding]; other site
1132507002753	active site
1132507002754	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
1132507002755	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1132507002756	NADP binding site [chemical binding]; other site
1132507002757	active site
1132507002758	putative substrate binding site [chemical binding]; other site
1132507002759	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
1132507002760	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1132507002761	substrate binding site; other site
1132507002762	tetramer interface; other site
1132507002763	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1132507002764	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
1132507002765	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1132507002766	catalytic loop [active]
1132507002767	iron binding site [ion binding]; other site
1132507002768	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1132507002769	FAD binding pocket [chemical binding]; other site
1132507002770	FAD binding motif [chemical binding]; other site
1132507002771	phosphate binding motif [ion binding]; other site
1132507002772	beta-alpha-beta structure motif; other site
1132507002773	NAD binding pocket [chemical binding]; other site
1132507002774	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1132507002775	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1132507002776	substrate binding site; other site
1132507002777	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
1132507002778	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
1132507002779	NAD binding site [chemical binding]; other site
1132507002780	homotetramer interface [polypeptide binding]; other site
1132507002781	homodimer interface [polypeptide binding]; other site
1132507002782	substrate binding site [chemical binding]; other site
1132507002783	active site
1132507002784	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1132507002785	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1132507002786	inhibitor-cofactor binding pocket; inhibition site
1132507002787	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507002788	catalytic residue [active]
1132507002789	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1132507002790	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1132507002791	active site
1132507002792	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
1132507002793	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1132507002794	NAD binding site [chemical binding]; other site
1132507002795	homotetramer interface [polypeptide binding]; other site
1132507002796	homodimer interface [polypeptide binding]; other site
1132507002797	active site
1132507002798	substrate binding site [chemical binding]; other site
1132507002799	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1132507002800	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
1132507002801	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1132507002802	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1132507002803	active site
1132507002804	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1132507002805	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1132507002806	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1132507002807	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1132507002808	active site
1132507002809	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1132507002810	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1132507002811	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1132507002812	Substrate binding site; other site
1132507002813	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1132507002814	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1132507002815	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
1132507002816	active site
1132507002817	substrate binding site [chemical binding]; other site
1132507002818	metal binding site [ion binding]; metal-binding site
1132507002819	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
1132507002820	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1132507002821	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
1132507002822	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1132507002823	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1132507002824	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1132507002825	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1132507002826	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1132507002827	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1132507002828	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1132507002829	chain length determinant protein WzzB; Provisional; Region: PRK15471
1132507002830	Chain length determinant protein; Region: Wzz; cl15801
1132507002831	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1132507002832	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1132507002833	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1132507002834	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1132507002835	metal binding site [ion binding]; metal-binding site
1132507002836	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1132507002837	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1132507002838	substrate binding site [chemical binding]; other site
1132507002839	glutamase interaction surface [polypeptide binding]; other site
1132507002840	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1132507002841	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1132507002842	catalytic residues [active]
1132507002843	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1132507002844	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1132507002845	putative active site [active]
1132507002846	oxyanion strand; other site
1132507002847	catalytic triad [active]
1132507002848	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1132507002849	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507002850	active site
1132507002851	motif I; other site
1132507002852	motif II; other site
1132507002853	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1132507002854	putative active site pocket [active]
1132507002855	4-fold oligomerization interface [polypeptide binding]; other site
1132507002856	metal binding residues [ion binding]; metal-binding site
1132507002857	3-fold/trimer interface [polypeptide binding]; other site
1132507002858	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1132507002859	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507002860	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507002861	homodimer interface [polypeptide binding]; other site
1132507002862	catalytic residue [active]
1132507002863	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1132507002864	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1132507002865	NAD binding site [chemical binding]; other site
1132507002866	dimerization interface [polypeptide binding]; other site
1132507002867	product binding site; other site
1132507002868	substrate binding site [chemical binding]; other site
1132507002869	zinc binding site [ion binding]; other site
1132507002870	catalytic residues [active]
1132507002871	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1132507002872	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1132507002873	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1132507002874	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1132507002875	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1132507002876	putative NAD(P) binding site [chemical binding]; other site
1132507002877	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507002878	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1132507002879	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507002880	dimerization interface [polypeptide binding]; other site
1132507002881	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1132507002882	exonuclease I; Provisional; Region: sbcB; PRK11779
1132507002883	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1132507002884	active site
1132507002885	catalytic site [active]
1132507002886	substrate binding site [chemical binding]; other site
1132507002887	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1132507002888	thiosulfate reductase PhsA; Provisional; Region: PRK15488
1132507002889	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1132507002890	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
1132507002891	putative [Fe4-S4] binding site [ion binding]; other site
1132507002892	putative molybdopterin cofactor binding site [chemical binding]; other site
1132507002893	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1132507002894	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
1132507002895	putative molybdopterin cofactor binding site; other site
1132507002896	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1132507002897	4Fe-4S binding domain; Region: Fer4; cl02805
1132507002898	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
1132507002899	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
1132507002900	DNA gyrase inhibitor; Provisional; Region: PRK10016
1132507002901	Predicted membrane protein [Function unknown]; Region: COG1289
1132507002902	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1132507002903	hypothetical protein; Provisional; Region: PRK05423
1132507002904	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
1132507002905	propionate kinase; Reviewed; Region: PRK12397
1132507002906	propionate/acetate kinase; Provisional; Region: PRK12379
1132507002907	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
1132507002908	G3 box; other site
1132507002909	Switch II region; other site
1132507002910	GTP/Mg2+ binding site [chemical binding]; other site
1132507002911	G4 box; other site
1132507002912	G5 box; other site
1132507002913	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1132507002914	putative hexamer interface [polypeptide binding]; other site
1132507002915	putative hexagonal pore; other site
1132507002916	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
1132507002917	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1132507002918	putative hexamer interface [polypeptide binding]; other site
1132507002919	putative hexagonal pore; other site
1132507002920	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1132507002921	putative hexamer interface [polypeptide binding]; other site
1132507002922	putative hexagonal pore; other site
1132507002923	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1132507002924	SLBB domain; Region: SLBB; pfam10531
1132507002925	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1132507002926	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1132507002927	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1132507002928	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
1132507002929	putative active site [active]
1132507002930	metal binding site [ion binding]; metal-binding site
1132507002931	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1132507002932	putative catalytic cysteine [active]
1132507002933	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
1132507002934	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
1132507002935	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cl01889
1132507002936	central pore; other site
1132507002937	Hexamer/Pentamer interface [polypeptide binding]; other site
1132507002938	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
1132507002939	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
1132507002940	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1132507002941	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1132507002942	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1132507002943	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
1132507002944	putative hexamer interface [polypeptide binding]; other site
1132507002945	putative hexagonal pore; other site
1132507002946	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1132507002947	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1132507002948	Hexamer interface [polypeptide binding]; other site
1132507002949	Putative hexagonal pore residue; other site
1132507002950	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
1132507002951	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
1132507002952	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
1132507002953	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
1132507002954	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
1132507002955	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
1132507002956	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
1132507002957	alpha-beta subunit interface [polypeptide binding]; other site
1132507002958	alpha-gamma subunit interface [polypeptide binding]; other site
1132507002959	active site
1132507002960	substrate and K+ binding site; other site
1132507002961	K+ binding site [ion binding]; other site
1132507002962	cobalamin binding site [chemical binding]; other site
1132507002963	propanediol utilization protein PduB; Provisional; Region: PRK15415
1132507002964	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
1132507002965	putative hexamer interface [polypeptide binding]; other site
1132507002966	putative hexagonal pore; other site
1132507002967	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
1132507002968	putative hexamer interface [polypeptide binding]; other site
1132507002969	putative hexagonal pore; other site
1132507002970	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1132507002971	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1132507002972	Hexamer interface [polypeptide binding]; other site
1132507002973	Putative hexagonal pore residue; other site
1132507002974	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1132507002975	amphipathic channel; other site
1132507002976	Asn-Pro-Ala signature motifs; other site
1132507002977	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
1132507002978	Sensory domain found in PocR; Region: PocR; pfam10114
1132507002979	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507002980	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1132507002981	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507002982	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1132507002983	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1132507002984	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1132507002985	catalytic triad [active]
1132507002986	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
1132507002987	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
1132507002988	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
1132507002989	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1132507002990	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1132507002991	active site
1132507002992	putative homodimer interface [polypeptide binding]; other site
1132507002993	SAM binding site [chemical binding]; other site
1132507002994	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
1132507002995	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507002996	S-adenosylmethionine binding site [chemical binding]; other site
1132507002997	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1132507002998	active site
1132507002999	SAM binding site [chemical binding]; other site
1132507003000	homodimer interface [polypeptide binding]; other site
1132507003001	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1132507003002	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1132507003003	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1132507003004	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1132507003005	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1132507003006	homodimer interface [polypeptide binding]; other site
1132507003007	active site
1132507003008	SAM binding site [chemical binding]; other site
1132507003009	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1132507003010	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
1132507003011	Class II Chelatase: a family of ATP-independent monomeric or homodimeric enzymes that catalyze the insertion of metal into protoporphyrin rings. This family includes protoporphyrin IX ferrochelatase (HemH), sirohydrochlorin ferrochelatase (SirB) and the...; Region: Chelatase_Class_II; cl02784
1132507003012	active site
1132507003013	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
1132507003014	Class II Chelatase: a family of ATP-independent monomeric or homodimeric enzymes that catalyze the insertion of metal into protoporphyrin rings. This family includes protoporphyrin IX ferrochelatase (HemH), sirohydrochlorin ferrochelatase (SirB) and the...; Region: Chelatase_Class_II; cl02784
1132507003015	active site
1132507003016	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
1132507003017	active site
1132507003018	N-terminal domain interface [polypeptide binding]; other site
1132507003019	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1132507003020	active site
1132507003021	SAM binding site [chemical binding]; other site
1132507003022	homodimer interface [polypeptide binding]; other site
1132507003023	cobalt transport protein CbiN; Provisional; Region: PRK02898
1132507003024	cobalt transport protein CbiQ; Provisional; Region: PRK15485
1132507003025	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
1132507003026	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1132507003027	Walker A/P-loop; other site
1132507003028	ATP binding site [chemical binding]; other site
1132507003029	Q-loop/lid; other site
1132507003030	ABC transporter signature motif; other site
1132507003031	Walker B; other site
1132507003032	D-loop; other site
1132507003033	H-loop/switch region; other site
1132507003034	cobyric acid synthase; Provisional; Region: PRK00784
1132507003035	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1132507003036	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1132507003037	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1132507003038	catalytic triad [active]
1132507003039	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1132507003040	homotrimer interface [polypeptide binding]; other site
1132507003041	Walker A motif; other site
1132507003042	GTP binding site [chemical binding]; other site
1132507003043	Walker B motif; other site
1132507003044	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1132507003045	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1132507003046	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1132507003047	putative dimer interface [polypeptide binding]; other site
1132507003048	active site pocket [active]
1132507003049	putative cataytic base [active]
1132507003050	L,D-transpeptidase; Provisional; Region: PRK10190
1132507003051	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1132507003052	MATE family multidrug exporter; Provisional; Region: PRK10189
1132507003053	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1132507003054	AMP nucleosidase; Provisional; Region: PRK08292
1132507003055	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1132507003056	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1132507003057	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1132507003058	MobA/MobL family; Region: MobA_MobL; pfam03389
1132507003059	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
1132507003060	Restriction endonuclease [Defense mechanisms]; Region: COG3587
1132507003061	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507003062	ATP binding site [chemical binding]; other site
1132507003063	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1132507003064	DNA methylase; Region: N6_N4_Mtase; pfam01555
1132507003065	DNA methylase; Region: N6_N4_Mtase; cl17433
1132507003066	integrase; Provisional; Region: PRK09692
1132507003067	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1132507003068	active site
1132507003069	Int/Topo IB signature motif; other site
1132507003070	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1132507003071	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1132507003072	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1132507003073	Catalytic site [active]
1132507003074	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1132507003075	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1132507003076	active site
1132507003077	DNA binding site [nucleotide binding]
1132507003078	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1132507003079	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1132507003080	DNA-binding site [nucleotide binding]; DNA binding site
1132507003081	RNA-binding motif; other site
1132507003082	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1132507003083	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1132507003084	trimer interface [polypeptide binding]; other site
1132507003085	eyelet of channel; other site
1132507003086	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1132507003087	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1132507003088	Zn2+ binding site [ion binding]; other site
1132507003089	Mg2+ binding site [ion binding]; other site
1132507003090	DNA cytosine methylase; Provisional; Region: PRK10458
1132507003091	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1132507003092	cofactor binding site; other site
1132507003093	DNA binding site [nucleotide binding]
1132507003094	substrate interaction site [chemical binding]; other site
1132507003095	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1132507003096	additional DNA contacts [nucleotide binding]; other site
1132507003097	mismatch recognition site; other site
1132507003098	active site
1132507003099	zinc binding site [ion binding]; other site
1132507003100	DNA intercalation site [nucleotide binding]; other site
1132507003101	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1132507003102	EamA-like transporter family; Region: EamA; pfam00892
1132507003103	EamA-like transporter family; Region: EamA; pfam00892
1132507003104	Protein of unknown function (DUF808); Region: DUF808; cl01002
1132507003105	Protein of unknown function (DUF808); Region: DUF808; cl01002
1132507003106	Uncharacterized small protein [Function unknown]; Region: COG5475
1132507003107	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1132507003108	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507003109	metal binding site [ion binding]; metal-binding site
1132507003110	active site
1132507003111	I-site; other site
1132507003112	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1132507003113	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507003114	active site
1132507003115	motif I; other site
1132507003116	motif II; other site
1132507003117	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1132507003118	hypothetical protein; Provisional; Region: PRK10708
1132507003119	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1132507003120	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507003121	DNA binding residues [nucleotide binding]
1132507003122	dimerization interface [polypeptide binding]; other site
1132507003123	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1132507003124	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1132507003125	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1132507003126	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1132507003127	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1132507003128	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1132507003129	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1132507003130	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1132507003131	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1132507003132	flagellar hook-length control protein; Provisional; Region: PRK10118
1132507003133	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
1132507003134	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1132507003135	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1132507003136	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1132507003137	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1132507003138	Walker A motif/ATP binding site; other site
1132507003139	Walker B motif; other site
1132507003140	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1132507003141	Flagellar assembly protein FliH; Region: FliH; pfam02108
1132507003142	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1132507003143	FliG C-terminal domain; Region: FliG_C; pfam01706
1132507003144	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1132507003145	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1132507003146	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1132507003147	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1132507003148	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1132507003149	CPxP  motif; other site
1132507003150	putative inner membrane protein; Provisional; Region: PRK11099
1132507003151	Sulphur transport; Region: Sulf_transp; pfam04143
1132507003152	lipoprotein; Provisional; Region: PRK10397
1132507003153	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1132507003154	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1132507003155	active site
1132507003156	Na/Ca binding site [ion binding]; other site
1132507003157	catalytic site [active]
1132507003158	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
1132507003159	flagellar protein FliS; Validated; Region: fliS; PRK05685
1132507003160	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1132507003161	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1132507003162	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1132507003163	flagellin; Validated; Region: PRK08026
1132507003164	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1132507003165	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
1132507003166	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1132507003167	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1132507003168	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1132507003169	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1132507003170	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1132507003171	DNA binding residues [nucleotide binding]
1132507003172	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1132507003173	cystine transporter subunit; Provisional; Region: PRK11260
1132507003174	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507003175	substrate binding pocket [chemical binding]; other site
1132507003176	membrane-bound complex binding site; other site
1132507003177	hinge residues; other site
1132507003178	D-cysteine desulfhydrase; Validated; Region: PRK03910
1132507003179	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1132507003180	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507003181	catalytic residue [active]
1132507003182	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1132507003183	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507003184	dimer interface [polypeptide binding]; other site
1132507003185	conserved gate region; other site
1132507003186	putative PBP binding loops; other site
1132507003187	ABC-ATPase subunit interface; other site
1132507003188	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1132507003189	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1132507003190	Walker A/P-loop; other site
1132507003191	ATP binding site [chemical binding]; other site
1132507003192	Q-loop/lid; other site
1132507003193	ABC transporter signature motif; other site
1132507003194	Walker B; other site
1132507003195	D-loop; other site
1132507003196	H-loop/switch region; other site
1132507003197	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1132507003198	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1132507003199	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1132507003200	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507003201	DNA binding residues [nucleotide binding]
1132507003202	dimerization interface [polypeptide binding]; other site
1132507003203	hypothetical protein; Provisional; Region: PRK10613
1132507003204	Response regulator receiver domain; Region: Response_reg; pfam00072
1132507003205	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507003206	active site
1132507003207	phosphorylation site [posttranslational modification]
1132507003208	intermolecular recognition site; other site
1132507003209	dimerization interface [polypeptide binding]; other site
1132507003210	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1132507003211	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507003212	dimerization interface [polypeptide binding]; other site
1132507003213	DNA binding residues [nucleotide binding]
1132507003214	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1132507003215	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1132507003216	GIY-YIG motif/motif A; other site
1132507003217	active site
1132507003218	catalytic site [active]
1132507003219	putative DNA binding site [nucleotide binding]; other site
1132507003220	metal binding site [ion binding]; metal-binding site
1132507003221	UvrB/uvrC motif; Region: UVR; pfam02151
1132507003222	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1132507003223	Helix-hairpin-helix motif; Region: HHH; pfam00633
1132507003224	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1132507003225	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
1132507003226	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
1132507003227	NlpC/P60 family; Region: NLPC_P60; cl17555
1132507003228	hypothetical protein; Provisional; Region: PRK10396
1132507003229	yecA family protein; Region: ygfB_yecA; TIGR02292
1132507003230	SEC-C motif; Region: SEC-C; pfam02810
1132507003231	tyrosine transporter TyrP; Provisional; Region: PRK15132
1132507003232	aromatic amino acid transport protein; Region: araaP; TIGR00837
1132507003233	probable metal-binding protein; Region: matur_matur; TIGR03853
1132507003234	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1132507003235	Ferritin-like domain; Region: Ferritin; pfam00210
1132507003236	ferroxidase diiron center [ion binding]; other site
1132507003237	YecR-like lipoprotein; Region: YecR; pfam13992
1132507003238	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1132507003239	Ferritin-like domain; Region: Ferritin; pfam00210
1132507003240	dinuclear metal binding motif [ion binding]; other site
1132507003241	DJ-1 family protein; Region: not_thiJ; TIGR01383
1132507003242	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1132507003243	conserved cys residue [active]
1132507003244	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1132507003245	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
1132507003246	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1132507003247	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1132507003248	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1132507003249	active site
1132507003250	homotetramer interface [polypeptide binding]; other site
1132507003251	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1132507003252	Ligand Binding Site [chemical binding]; other site
1132507003253	transcriptional activator FlhD; Provisional; Region: PRK02909
1132507003254	transcriptional activator FlhC; Provisional; Region: PRK12722
1132507003255	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1132507003256	flagellar motor protein MotA; Validated; Region: PRK09110
1132507003257	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1132507003258	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1132507003259	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1132507003260	ligand binding site [chemical binding]; other site
1132507003261	chemotaxis protein CheA; Provisional; Region: PRK10547
1132507003262	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1132507003263	putative binding surface; other site
1132507003264	active site
1132507003265	CheY binding; Region: CheY-binding; pfam09078
1132507003266	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1132507003267	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507003268	ATP binding site [chemical binding]; other site
1132507003269	Mg2+ binding site [ion binding]; other site
1132507003270	G-X-G motif; other site
1132507003271	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1132507003272	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1132507003273	putative CheA interaction surface; other site
1132507003274	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1132507003275	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1132507003276	dimer interface [polypeptide binding]; other site
1132507003277	ligand binding site [chemical binding]; other site
1132507003278	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507003279	dimerization interface [polypeptide binding]; other site
1132507003280	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1132507003281	dimer interface [polypeptide binding]; other site
1132507003282	putative CheW interface [polypeptide binding]; other site
1132507003283	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1132507003284	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1132507003285	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507003286	S-adenosylmethionine binding site [chemical binding]; other site
1132507003287	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1132507003288	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507003289	active site
1132507003290	phosphorylation site [posttranslational modification]
1132507003291	intermolecular recognition site; other site
1132507003292	dimerization interface [polypeptide binding]; other site
1132507003293	CheB methylesterase; Region: CheB_methylest; pfam01339
1132507003294	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1132507003295	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507003296	active site
1132507003297	phosphorylation site [posttranslational modification]
1132507003298	intermolecular recognition site; other site
1132507003299	dimerization interface [polypeptide binding]; other site
1132507003300	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1132507003301	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1132507003302	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1132507003303	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1132507003304	FHIPEP family; Region: FHIPEP; pfam00771
1132507003305	Flagellar protein FlhE; Region: FlhE; pfam06366
1132507003306	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1132507003307	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1132507003308	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1132507003309	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1132507003310	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1132507003311	arginyl-tRNA synthetase; Region: argS; TIGR00456
1132507003312	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1132507003313	active site
1132507003314	HIGH motif; other site
1132507003315	KMSK motif region; other site
1132507003316	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1132507003317	tRNA binding surface [nucleotide binding]; other site
1132507003318	anticodon binding site; other site
1132507003319	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1132507003320	putative metal binding site [ion binding]; other site
1132507003321	copper homeostasis protein CutC; Provisional; Region: PRK11572
1132507003322	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507003323	S-adenosylmethionine binding site [chemical binding]; other site
1132507003324	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507003325	S-adenosylmethionine binding site [chemical binding]; other site
1132507003326	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1132507003327	hypothetical protein; Provisional; Region: PRK10302
1132507003328	Isochorismatase family; Region: Isochorismatase; pfam00857
1132507003329	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1132507003330	catalytic triad [active]
1132507003331	conserved cis-peptide bond; other site
1132507003332	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1132507003333	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1132507003334	dimer interface [polypeptide binding]; other site
1132507003335	anticodon binding site; other site
1132507003336	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1132507003337	homodimer interface [polypeptide binding]; other site
1132507003338	motif 1; other site
1132507003339	active site
1132507003340	motif 2; other site
1132507003341	GAD domain; Region: GAD; pfam02938
1132507003342	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1132507003343	active site
1132507003344	motif 3; other site
1132507003345	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1132507003346	nudix motif; other site
1132507003347	hypothetical protein; Validated; Region: PRK00110
1132507003348	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1132507003349	active site
1132507003350	putative DNA-binding cleft [nucleotide binding]; other site
1132507003351	dimer interface [polypeptide binding]; other site
1132507003352	hypothetical protein; Provisional; Region: PRK11470
1132507003353	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1132507003354	RuvA N terminal domain; Region: RuvA_N; pfam01330
1132507003355	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1132507003356	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1132507003357	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507003358	Walker A motif; other site
1132507003359	ATP binding site [chemical binding]; other site
1132507003360	Walker B motif; other site
1132507003361	arginine finger; other site
1132507003362	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1132507003363	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1132507003364	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1132507003365	ABC-ATPase subunit  interface; other site
1132507003366	dimer interface [polypeptide binding]; other site
1132507003367	putative PBP binding regions; other site
1132507003368	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507003369	Q-loop/lid; other site
1132507003370	ABC transporter signature motif; other site
1132507003371	Walker B; other site
1132507003372	D-loop; other site
1132507003373	H-loop/switch region; other site
1132507003374	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1132507003375	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1132507003376	metal binding site [ion binding]; metal-binding site
1132507003377	putative peptidase; Provisional; Region: PRK11649
1132507003378	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1132507003379	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1132507003380	Peptidase family M23; Region: Peptidase_M23; pfam01551
1132507003381	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1132507003382	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1132507003383	putative acyl-acceptor binding pocket; other site
1132507003384	pyruvate kinase; Provisional; Region: PRK05826
1132507003385	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1132507003386	domain interfaces; other site
1132507003387	active site
1132507003388	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1132507003389	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1132507003390	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1132507003391	putative active site [active]
1132507003392	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1132507003393	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1132507003394	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1132507003395	phosphogluconate dehydratase; Validated; Region: PRK09054
1132507003396	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1132507003397	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1132507003398	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1132507003399	active site
1132507003400	intersubunit interface [polypeptide binding]; other site
1132507003401	catalytic residue [active]
1132507003402	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1132507003403	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1132507003404	ATP-grasp domain; Region: ATP-grasp; pfam02222
1132507003405	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
1132507003406	hypothetical protein; Provisional; Region: PRK13680
1132507003407	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1132507003408	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1132507003409	putative metal binding site [ion binding]; other site
1132507003410	protease 2; Provisional; Region: PRK10115
1132507003411	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1132507003412	exodeoxyribonuclease X; Provisional; Region: PRK07983
1132507003413	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1132507003414	active site
1132507003415	catalytic site [active]
1132507003416	substrate binding site [chemical binding]; other site
1132507003417	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1132507003418	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
1132507003419	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1132507003420	hypothetical protein; Provisional; Region: PRK10301
1132507003421	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1132507003422	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1132507003423	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1132507003424	DNA binding site [nucleotide binding]
1132507003425	active site
1132507003426	Int/Topo IB signature motif; other site
1132507003427	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1132507003428	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507003429	metal binding site [ion binding]; metal-binding site
1132507003430	active site
1132507003431	I-site; other site
1132507003432	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
1132507003433	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1132507003434	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1132507003435	EamA-like transporter family; Region: EamA; pfam00892
1132507003436	EamA-like transporter family; Region: EamA; pfam00892
1132507003437	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1132507003438	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1132507003439	MULE transposase domain; Region: MULE; pfam10551
1132507003440	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
1132507003441	SopE GEF domain; Region: SopE_GEF; pfam07487
1132507003442	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
1132507003443	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1132507003444	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1132507003445	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1132507003446	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1132507003447	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
1132507003448	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1132507003449	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1132507003450	mce related protein; Region: MCE; pfam02470
1132507003451	mce related protein; Region: MCE; pfam02470
1132507003452	mce related protein; Region: MCE; pfam02470
1132507003453	mce related protein; Region: MCE; pfam02470
1132507003454	mce related protein; Region: MCE; pfam02470
1132507003455	mce related protein; Region: MCE; pfam02470
1132507003456	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1132507003457	Paraquat-inducible protein A; Region: PqiA; pfam04403
1132507003458	Paraquat-inducible protein A; Region: PqiA; pfam04403
1132507003459	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1132507003460	GAF domain; Region: GAF_2; pfam13185
1132507003461	ProP expression regulator; Provisional; Region: PRK04950
1132507003462	ProQ/FINO family; Region: ProQ; pfam04352
1132507003463	carboxy-terminal protease; Provisional; Region: PRK11186
1132507003464	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1132507003465	protein binding site [polypeptide binding]; other site
1132507003466	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1132507003467	Catalytic dyad [active]
1132507003468	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1132507003469	heat shock protein HtpX; Provisional; Region: PRK05457
1132507003470	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1132507003471	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1132507003472	dimerization interface [polypeptide binding]; other site
1132507003473	putative Zn2+ binding site [ion binding]; other site
1132507003474	putative DNA binding site [nucleotide binding]; other site
1132507003475	Bacterial transcriptional regulator; Region: IclR; pfam01614
1132507003476	YobH-like protein; Region: YobH; pfam13996
1132507003477	PhoPQ regulatory protein; Provisional; Region: PRK10299
1132507003478	YebO-like protein; Region: YebO; pfam13974
1132507003479	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1132507003480	DNA-binding site [nucleotide binding]; DNA binding site
1132507003481	RNA-binding motif; other site
1132507003482	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1132507003483	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1132507003484	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1132507003485	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1132507003486	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507003487	S-adenosylmethionine binding site [chemical binding]; other site
1132507003488	hypothetical protein; Provisional; Region: PRK11469
1132507003489	Domain of unknown function DUF; Region: DUF204; pfam02659
1132507003490	Domain of unknown function DUF; Region: DUF204; pfam02659
1132507003491	hypothetical protein; Provisional; Region: PRK02913
1132507003492	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1132507003493	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1132507003494	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1132507003495	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1132507003496	active pocket/dimerization site; other site
1132507003497	active site
1132507003498	phosphorylation site [posttranslational modification]
1132507003499	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1132507003500	active site
1132507003501	phosphorylation site [posttranslational modification]
1132507003502	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1132507003503	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1132507003504	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1132507003505	Transporter associated domain; Region: CorC_HlyC; smart01091
1132507003506	phage resistance protein; Provisional; Region: PRK10551
1132507003507	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1132507003508	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507003509	L-serine deaminase; Provisional; Region: PRK15023
1132507003510	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1132507003511	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1132507003512	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1132507003513	putative active site [active]
1132507003514	putative CoA binding site [chemical binding]; other site
1132507003515	nudix motif; other site
1132507003516	metal binding site [ion binding]; metal-binding site
1132507003517	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1132507003518	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1132507003519	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
1132507003520	hypothetical protein; Provisional; Region: PRK05114
1132507003521	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1132507003522	homotrimer interaction site [polypeptide binding]; other site
1132507003523	putative active site [active]
1132507003524	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1132507003525	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1132507003526	DEAD_2; Region: DEAD_2; pfam06733
1132507003527	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1132507003528	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1132507003529	Glycoprotease family; Region: Peptidase_M22; pfam00814
1132507003530	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
1132507003531	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1132507003532	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1132507003533	acyl-activating enzyme (AAE) consensus motif; other site
1132507003534	putative AMP binding site [chemical binding]; other site
1132507003535	putative active site [active]
1132507003536	putative CoA binding site [chemical binding]; other site
1132507003537	ribonuclease D; Provisional; Region: PRK10829
1132507003538	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1132507003539	catalytic site [active]
1132507003540	putative active site [active]
1132507003541	putative substrate binding site [chemical binding]; other site
1132507003542	HRDC domain; Region: HRDC; cl02578
1132507003543	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1132507003544	cell division inhibitor MinD; Provisional; Region: PRK10818
1132507003545	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1132507003546	Switch I; other site
1132507003547	Switch II; other site
1132507003548	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1132507003549	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1132507003550	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1132507003551	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
1132507003552	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1132507003553	hypothetical protein; Provisional; Region: PRK10691
1132507003554	hypothetical protein; Provisional; Region: PRK05170
1132507003555	GnsA/GnsB family; Region: GnsAB; pfam08178
1132507003556	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1132507003557	disulfide bond formation protein B; Provisional; Region: PRK01749
1132507003558	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1132507003559	transmembrane helices; other site
1132507003560	fatty acid metabolism regulator; Provisional; Region: PRK04984
1132507003561	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507003562	DNA-binding site [nucleotide binding]; DNA binding site
1132507003563	FadR C-terminal domain; Region: FadR_C; pfam07840
1132507003564	SpoVR family protein; Provisional; Region: PRK11767
1132507003565	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1132507003566	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1132507003567	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1132507003568	alanine racemase; Reviewed; Region: dadX; PRK03646
1132507003569	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1132507003570	active site
1132507003571	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1132507003572	substrate binding site [chemical binding]; other site
1132507003573	catalytic residues [active]
1132507003574	dimer interface [polypeptide binding]; other site
1132507003575	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1132507003576	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1132507003577	TrkA-C domain; Region: TrkA_C; pfam02080
1132507003578	Transporter associated domain; Region: CorC_HlyC; smart01091
1132507003579	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1132507003580	dimer interface [polypeptide binding]; other site
1132507003581	catalytic triad [active]
1132507003582	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1132507003583	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1132507003584	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1132507003585	catalytic residue [active]
1132507003586	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1132507003587	Flagellar regulator YcgR; Region: YcgR; pfam07317
1132507003588	PilZ domain; Region: PilZ; pfam07238
1132507003589	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
1132507003590	Trehalase; Region: Trehalase; cl17346
1132507003591	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1132507003592	Trehalase; Region: Trehalase; cl17346
1132507003593	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1132507003594	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1132507003595	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1132507003596	NAD(P) binding site [chemical binding]; other site
1132507003597	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
1132507003598	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1132507003599	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
1132507003600	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1132507003601	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1132507003602	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1132507003603	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1132507003604	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1132507003605	putative substrate-binding site; other site
1132507003606	nickel binding site [ion binding]; other site
1132507003607	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
1132507003608	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1132507003609	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1132507003610	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
1132507003611	Protein of unknown function (DUF4427); Region: DUF4427; pfam14468
1132507003612	GTP-binding protein YchF; Reviewed; Region: PRK09601
1132507003613	YchF GTPase; Region: YchF; cd01900
1132507003614	G1 box; other site
1132507003615	GTP/Mg2+ binding site [chemical binding]; other site
1132507003616	Switch I region; other site
1132507003617	G2 box; other site
1132507003618	Switch II region; other site
1132507003619	G3 box; other site
1132507003620	G4 box; other site
1132507003621	G5 box; other site
1132507003622	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1132507003623	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1132507003624	putative active site [active]
1132507003625	catalytic residue [active]
1132507003626	hypothetical protein; Provisional; Region: PRK10692
1132507003627	putative transporter; Provisional; Region: PRK11660
1132507003628	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1132507003629	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1132507003630	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1132507003631	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1132507003632	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1132507003633	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1132507003634	active site
1132507003635	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1132507003636	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1132507003637	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
1132507003638	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1132507003639	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1132507003640	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1132507003641	tRNA; other site
1132507003642	putative tRNA binding site [nucleotide binding]; other site
1132507003643	putative NADP binding site [chemical binding]; other site
1132507003644	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1132507003645	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1132507003646	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1132507003647	RF-1 domain; Region: RF-1; pfam00472
1132507003648	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1132507003649	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507003650	hypothetical protein; Provisional; Region: PRK10278
1132507003651	hypothetical protein; Provisional; Region: PRK10941
1132507003652	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1132507003653	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
1132507003654	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1132507003655	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507003656	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
1132507003657	pertussis toxin-like subunit ArtA; Provisional; Region: PRK15272
1132507003658	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1132507003659	Protein of unknown function (DUF1353); Region: DUF1353; pfam07087
1132507003660	CdtB, the catalytic DNase I-like subunit of cytolethal distending toxin (CDT) protein; Region: CdtB; cd09081
1132507003661	putative catalytic site [active]
1132507003662	CdtC interface [polypeptide binding]; other site
1132507003663	heterotrimer interface [polypeptide binding]; other site
1132507003664	CdtA interface [polypeptide binding]; other site
1132507003665	putative metal binding site [ion binding]; other site
1132507003666	putative phosphate binding site [ion binding]; other site
1132507003667	putative transposase OrfB; Reviewed; Region: PHA02517
1132507003668	DinI-like family; Region: DinI; pfam06183
1132507003669	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1132507003670	Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652
1132507003671	putative sugar binding sites [chemical binding]; other site
1132507003672	Q-X-W motif; other site
1132507003673	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1132507003674	lysozyme inhibitor; Provisional; Region: PRK13791
1132507003675	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1132507003676	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1132507003677	putative dimer interface [polypeptide binding]; other site
1132507003678	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
1132507003679	BNR repeat-like domain; Region: BNR_2; pfam13088
1132507003680	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1132507003681	TRL-like protein family; Region: TRL; pfam13146
1132507003682	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
1132507003683	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1132507003684	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1132507003685	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507003686	dimer interface [polypeptide binding]; other site
1132507003687	conserved gate region; other site
1132507003688	ABC-ATPase subunit interface; other site
1132507003689	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1132507003690	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507003691	dimer interface [polypeptide binding]; other site
1132507003692	conserved gate region; other site
1132507003693	putative PBP binding loops; other site
1132507003694	ABC-ATPase subunit interface; other site
1132507003695	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507003696	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1132507003697	Walker A/P-loop; other site
1132507003698	ATP binding site [chemical binding]; other site
1132507003699	Q-loop/lid; other site
1132507003700	ABC transporter signature motif; other site
1132507003701	Walker B; other site
1132507003702	D-loop; other site
1132507003703	H-loop/switch region; other site
1132507003704	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507003705	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1132507003706	Walker A/P-loop; other site
1132507003707	ATP binding site [chemical binding]; other site
1132507003708	Q-loop/lid; other site
1132507003709	ABC transporter signature motif; other site
1132507003710	Walker B; other site
1132507003711	D-loop; other site
1132507003712	H-loop/switch region; other site
1132507003713	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1132507003714	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1132507003715	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1132507003716	aminoglycoside resistance protein; Provisional; Region: PRK13746
1132507003717	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1132507003718	active site
1132507003719	NTP binding site [chemical binding]; other site
1132507003720	metal binding triad [ion binding]; metal-binding site
1132507003721	antibiotic binding site [chemical binding]; other site
1132507003722	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1132507003723	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507003724	DNA binding residues [nucleotide binding]
1132507003725	transcriptional regulator MirA; Provisional; Region: PRK15043
1132507003726	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
1132507003727	DNA binding residues [nucleotide binding]
1132507003728	dimer interface [polypeptide binding]; other site
1132507003729	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1132507003730	chorismate mutase; Provisional; Region: PRK08055
1132507003731	leucine export protein LeuE; Provisional; Region: PRK10958
1132507003732	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1132507003733	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1132507003734	Phage Tail Collar Domain; Region: Collar; pfam07484
1132507003735	hypothetical protein; Provisional; Region: PRK10457
1132507003736	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507003737	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1132507003738	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1132507003739	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1132507003740	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1132507003741	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1132507003742	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507003743	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1132507003744	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507003745	Predicted membrane protein [Function unknown]; Region: COG2707
1132507003746	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1132507003747	putative deacylase active site [active]
1132507003748	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1132507003749	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507003750	metal binding site [ion binding]; metal-binding site
1132507003751	active site
1132507003752	I-site; other site
1132507003753	hypothetical protein; Provisional; Region: PRK05325
1132507003754	PrkA family serine protein kinase; Provisional; Region: PRK15455
1132507003755	AAA ATPase domain; Region: AAA_16; pfam13191
1132507003756	Walker A motif; other site
1132507003757	ATP binding site [chemical binding]; other site
1132507003758	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1132507003759	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1132507003760	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1132507003761	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1132507003762	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1132507003763	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1132507003764	active site
1132507003765	catalytic tetrad [active]
1132507003766	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1132507003767	active site
1132507003768	phosphate binding residues; other site
1132507003769	catalytic residues [active]
1132507003770	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
1132507003771	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1132507003772	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1132507003773	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1132507003774	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1132507003775	SelR domain; Region: SelR; pfam01641
1132507003776	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1132507003777	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1132507003778	Isochorismatase family; Region: Isochorismatase; pfam00857
1132507003779	catalytic triad [active]
1132507003780	metal binding site [ion binding]; metal-binding site
1132507003781	conserved cis-peptide bond; other site
1132507003782	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1132507003783	active site
1132507003784	homodimer interface [polypeptide binding]; other site
1132507003785	protease 4; Provisional; Region: PRK10949
1132507003786	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1132507003787	tandem repeat interface [polypeptide binding]; other site
1132507003788	oligomer interface [polypeptide binding]; other site
1132507003789	active site residues [active]
1132507003790	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1132507003791	tandem repeat interface [polypeptide binding]; other site
1132507003792	oligomer interface [polypeptide binding]; other site
1132507003793	active site residues [active]
1132507003794	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1132507003795	putative FMN binding site [chemical binding]; other site
1132507003796	selenophosphate synthetase; Provisional; Region: PRK00943
1132507003797	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1132507003798	dimerization interface [polypeptide binding]; other site
1132507003799	putative ATP binding site [chemical binding]; other site
1132507003800	DNA topoisomerase III; Provisional; Region: PRK07726
1132507003801	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1132507003802	active site
1132507003803	putative interdomain interaction site [polypeptide binding]; other site
1132507003804	putative metal-binding site [ion binding]; other site
1132507003805	putative nucleotide binding site [chemical binding]; other site
1132507003806	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1132507003807	domain I; other site
1132507003808	DNA binding groove [nucleotide binding]
1132507003809	phosphate binding site [ion binding]; other site
1132507003810	domain II; other site
1132507003811	domain III; other site
1132507003812	nucleotide binding site [chemical binding]; other site
1132507003813	catalytic site [active]
1132507003814	domain IV; other site
1132507003815	glutamate dehydrogenase; Provisional; Region: PRK09414
1132507003816	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1132507003817	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1132507003818	NAD(P) binding site [chemical binding]; other site
1132507003819	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1132507003820	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1132507003821	active site
1132507003822	8-oxo-dGMP binding site [chemical binding]; other site
1132507003823	nudix motif; other site
1132507003824	metal binding site [ion binding]; metal-binding site
1132507003825	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1132507003826	putative catalytic site [active]
1132507003827	putative phosphate binding site [ion binding]; other site
1132507003828	active site
1132507003829	metal binding site A [ion binding]; metal-binding site
1132507003830	DNA binding site [nucleotide binding]
1132507003831	putative AP binding site [nucleotide binding]; other site
1132507003832	putative metal binding site B [ion binding]; other site
1132507003833	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1132507003834	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1132507003835	inhibitor-cofactor binding pocket; inhibition site
1132507003836	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507003837	catalytic residue [active]
1132507003838	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1132507003839	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1132507003840	NAD(P) binding site [chemical binding]; other site
1132507003841	catalytic residues [active]
1132507003842	succinylarginine dihydrolase; Provisional; Region: PRK13281
1132507003843	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1132507003844	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1132507003845	putative active site [active]
1132507003846	Zn binding site [ion binding]; other site
1132507003847	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1132507003848	dimer interface [polypeptide binding]; other site
1132507003849	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1132507003850	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1132507003851	GIY-YIG motif/motif A; other site
1132507003852	active site
1132507003853	catalytic site [active]
1132507003854	putative DNA binding site [nucleotide binding]; other site
1132507003855	metal binding site [ion binding]; metal-binding site
1132507003856	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1132507003857	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1132507003858	homodimer interface [polypeptide binding]; other site
1132507003859	NAD binding pocket [chemical binding]; other site
1132507003860	ATP binding pocket [chemical binding]; other site
1132507003861	Mg binding site [ion binding]; other site
1132507003862	active-site loop [active]
1132507003863	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1132507003864	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1132507003865	active site
1132507003866	P-loop; other site
1132507003867	phosphorylation site [posttranslational modification]
1132507003868	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1132507003869	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1132507003870	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1132507003871	methionine cluster; other site
1132507003872	active site
1132507003873	phosphorylation site [posttranslational modification]
1132507003874	metal binding site [ion binding]; metal-binding site
1132507003875	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1132507003876	Cupin domain; Region: Cupin_2; pfam07883
1132507003877	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507003878	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1132507003879	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1132507003880	NAD binding site [chemical binding]; other site
1132507003881	sugar binding site [chemical binding]; other site
1132507003882	divalent metal binding site [ion binding]; other site
1132507003883	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1132507003884	dimer interface [polypeptide binding]; other site
1132507003885	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1132507003886	putative active site [active]
1132507003887	YdjC motif; other site
1132507003888	Mg binding site [ion binding]; other site
1132507003889	putative homodimer interface [polypeptide binding]; other site
1132507003890	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507003891	hydroperoxidase II; Provisional; Region: katE; PRK11249
1132507003892	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1132507003893	tetramer interface [polypeptide binding]; other site
1132507003894	heme binding pocket [chemical binding]; other site
1132507003895	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1132507003896	domain interactions; other site
1132507003897	cell division modulator; Provisional; Region: PRK10113
1132507003898	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1132507003899	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1132507003900	inner membrane protein; Provisional; Region: PRK11648
1132507003901	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1132507003902	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1132507003903	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507003904	motif II; other site
1132507003905	YniB-like protein; Region: YniB; pfam14002
1132507003906	Phosphotransferase enzyme family; Region: APH; pfam01636
1132507003907	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1132507003908	active site
1132507003909	ATP binding site [chemical binding]; other site
1132507003910	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1132507003911	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1132507003912	6-phosphofructokinase 2; Provisional; Region: PRK10294
1132507003913	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1132507003914	putative substrate binding site [chemical binding]; other site
1132507003915	putative ATP binding site [chemical binding]; other site
1132507003916	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1132507003917	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
1132507003918	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1132507003919	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1132507003920	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1132507003921	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1132507003922	active site
1132507003923	dimer interface [polypeptide binding]; other site
1132507003924	motif 1; other site
1132507003925	motif 2; other site
1132507003926	motif 3; other site
1132507003927	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1132507003928	anticodon binding site; other site
1132507003929	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1132507003930	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1132507003931	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1132507003932	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1132507003933	23S rRNA binding site [nucleotide binding]; other site
1132507003934	L21 binding site [polypeptide binding]; other site
1132507003935	L13 binding site [polypeptide binding]; other site
1132507003936	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1132507003937	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1132507003938	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1132507003939	dimer interface [polypeptide binding]; other site
1132507003940	motif 1; other site
1132507003941	active site
1132507003942	motif 2; other site
1132507003943	motif 3; other site
1132507003944	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1132507003945	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1132507003946	putative tRNA-binding site [nucleotide binding]; other site
1132507003947	B3/4 domain; Region: B3_4; pfam03483
1132507003948	tRNA synthetase B5 domain; Region: B5; smart00874
1132507003949	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1132507003950	dimer interface [polypeptide binding]; other site
1132507003951	motif 1; other site
1132507003952	motif 3; other site
1132507003953	motif 2; other site
1132507003954	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1132507003955	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1132507003956	IHF dimer interface [polypeptide binding]; other site
1132507003957	IHF - DNA interface [nucleotide binding]; other site
1132507003958	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1132507003959	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1132507003960	ABC-ATPase subunit  interface; other site
1132507003961	dimer interface [polypeptide binding]; other site
1132507003962	putative PBP binding regions; other site
1132507003963	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1132507003964	catalytic residues [active]
1132507003965	dimer interface [polypeptide binding]; other site
1132507003966	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
1132507003967	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1132507003968	Walker A/P-loop; other site
1132507003969	ATP binding site [chemical binding]; other site
1132507003970	Q-loop/lid; other site
1132507003971	ABC transporter signature motif; other site
1132507003972	Walker B; other site
1132507003973	D-loop; other site
1132507003974	H-loop/switch region; other site
1132507003975	NlpC/P60 family; Region: NLPC_P60; pfam00877
1132507003976	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
1132507003977	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1132507003978	hypothetical protein; Validated; Region: PRK00029
1132507003979	hypothetical protein; Provisional; Region: PRK10183
1132507003980	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1132507003981	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1132507003982	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1132507003983	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1132507003984	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1132507003985	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1132507003986	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1132507003987	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1132507003988	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1132507003989	active site
1132507003990	catalytic residue [active]
1132507003991	dimer interface [polypeptide binding]; other site
1132507003992	putative inner membrane protein; Provisional; Region: PRK10983
1132507003993	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1132507003994	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1132507003995	FAD binding domain; Region: FAD_binding_4; pfam01565
1132507003996	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1132507003997	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1132507003998	CoenzymeA binding site [chemical binding]; other site
1132507003999	subunit interaction site [polypeptide binding]; other site
1132507004000	PHB binding site; other site
1132507004001	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1132507004002	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1132507004003	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1132507004004	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1132507004005	putative ABC transporter; Region: ycf24; CHL00085
1132507004006	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1132507004007	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1132507004008	Walker A/P-loop; other site
1132507004009	ATP binding site [chemical binding]; other site
1132507004010	Q-loop/lid; other site
1132507004011	ABC transporter signature motif; other site
1132507004012	Walker B; other site
1132507004013	D-loop; other site
1132507004014	H-loop/switch region; other site
1132507004015	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1132507004016	FeS assembly protein SufD; Region: sufD; TIGR01981
1132507004017	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1132507004018	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1132507004019	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1132507004020	catalytic residue [active]
1132507004021	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1132507004022	murein lipoprotein; Provisional; Region: PRK15396
1132507004023	murein lipoprotein; Provisional; Region: PRK15396
1132507004024	pyruvate kinase; Provisional; Region: PRK09206
1132507004025	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1132507004026	domain interfaces; other site
1132507004027	active site
1132507004028	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1132507004029	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1132507004030	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1132507004031	tetrathionate reductase subunit A; Provisional; Region: PRK14991
1132507004032	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
1132507004033	putative [Fe4-S4] binding site [ion binding]; other site
1132507004034	putative molybdopterin cofactor binding site [chemical binding]; other site
1132507004035	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
1132507004036	putative molybdopterin cofactor binding site; other site
1132507004037	tetrathionate reductase subunit C; Provisional; Region: PRK14992
1132507004038	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1132507004039	tetrathionate reductase subunit B; Provisional; Region: PRK14993
1132507004040	4Fe-4S binding domain; Region: Fer4; pfam00037
1132507004041	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1132507004042	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1132507004043	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1132507004044	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507004045	dimer interface [polypeptide binding]; other site
1132507004046	phosphorylation site [posttranslational modification]
1132507004047	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507004048	ATP binding site [chemical binding]; other site
1132507004049	Mg2+ binding site [ion binding]; other site
1132507004050	G-X-G motif; other site
1132507004051	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1132507004052	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507004053	active site
1132507004054	phosphorylation site [posttranslational modification]
1132507004055	intermolecular recognition site; other site
1132507004056	dimerization interface [polypeptide binding]; other site
1132507004057	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507004058	DNA binding residues [nucleotide binding]
1132507004059	dimerization interface [polypeptide binding]; other site
1132507004060	hypothetical protein; Provisional; Region: PRK10292
1132507004061	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1132507004062	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1132507004063	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
1132507004064	transcriptional regulator MirA; Provisional; Region: PRK15043
1132507004065	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1132507004066	DNA binding residues [nucleotide binding]
1132507004067	two component system sensor kinase SsrB; Provisional; Region: PRK15369
1132507004068	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507004069	active site
1132507004070	phosphorylation site [posttranslational modification]
1132507004071	intermolecular recognition site; other site
1132507004072	dimerization interface [polypeptide binding]; other site
1132507004073	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507004074	DNA binding residues [nucleotide binding]
1132507004075	dimerization interface [polypeptide binding]; other site
1132507004076	two component system sensor kinase SsrA; Provisional; Region: PRK15347
1132507004077	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507004078	dimerization interface [polypeptide binding]; other site
1132507004079	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507004080	dimer interface [polypeptide binding]; other site
1132507004081	phosphorylation site [posttranslational modification]
1132507004082	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507004083	ATP binding site [chemical binding]; other site
1132507004084	Mg2+ binding site [ion binding]; other site
1132507004085	G-X-G motif; other site
1132507004086	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507004087	active site
1132507004088	phosphorylation site [posttranslational modification]
1132507004089	intermolecular recognition site; other site
1132507004090	dimerization interface [polypeptide binding]; other site
1132507004091	outer membrane secretin SsaC; Provisional; Region: PRK15346
1132507004092	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1132507004093	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1132507004094	type III secretion system protein SsaD; Provisional; Region: PRK15367
1132507004095	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
1132507004096	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
1132507004097	pathogenicity island 2 effector protein SseB; Provisional; Region: PRK15364
1132507004098	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
1132507004099	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
1132507004100	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
1132507004101	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
1132507004102	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
1132507004103	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1132507004104	TPR motif; other site
1132507004105	binding surface
1132507004106	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
1132507004107	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
1132507004108	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
1132507004109	type III secretion system protein SsaH; Provisional; Region: PRK15356
1132507004110	type III secretion system protein SsaI; Provisional; Region: PRK15355
1132507004111	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
1132507004112	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
1132507004113	type III secretion system protein SsaK; Provisional; Region: PRK15354
1132507004114	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
1132507004115	type III secretion system protein SsaL; Provisional; Region: PRK15345
1132507004116	HrpJ-like domain; Region: HrpJ; pfam07201
1132507004117	TyeA; Region: TyeA; cl07611
1132507004118	type III secretion system protein SsaM; Provisional; Region: PRK15353
1132507004119	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
1132507004120	FHIPEP family; Region: FHIPEP; pfam00771
1132507004121	type III secretion system ATPase SsaN; Validated; Region: PRK07594
1132507004122	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1132507004123	Walker A motif; other site
1132507004124	ATP binding site [chemical binding]; other site
1132507004125	Walker B motif; other site
1132507004126	type III secretion system protein SsaO; Provisional; Region: PRK15352
1132507004127	type III secretion system protein SsaP; Provisional; Region: PRK15351
1132507004128	type III secretion system protein SsaQ; Validated; Region: PRK08035
1132507004129	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1132507004130	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
1132507004131	Bacterial export proteins, family 1; Region: Bac_export_1; cl00734
1132507004132	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
1132507004133	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1132507004134	multidrug efflux protein; Reviewed; Region: PRK01766
1132507004135	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1132507004136	cation binding site [ion binding]; other site
1132507004137	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1132507004138	Lumazine binding domain; Region: Lum_binding; pfam00677
1132507004139	Lumazine binding domain; Region: Lum_binding; pfam00677
1132507004140	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1132507004141	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507004142	S-adenosylmethionine binding site [chemical binding]; other site
1132507004143	putative transporter; Provisional; Region: PRK11043
1132507004144	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507004145	putative substrate translocation pore; other site
1132507004146	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1132507004147	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507004148	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507004149	dimerization interface [polypeptide binding]; other site
1132507004150	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1132507004151	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507004152	DNA binding site [nucleotide binding]
1132507004153	domain linker motif; other site
1132507004154	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1132507004155	dimerization interface [polypeptide binding]; other site
1132507004156	ligand binding site [chemical binding]; other site
1132507004157	superoxide dismutase; Provisional; Region: PRK10543
1132507004158	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1132507004159	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1132507004160	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1132507004161	NlpC/P60 family; Region: NLPC_P60; pfam00877
1132507004162	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1132507004163	putative GSH binding site [chemical binding]; other site
1132507004164	catalytic residues [active]
1132507004165	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1132507004166	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1132507004167	dimer interface [polypeptide binding]; other site
1132507004168	catalytic site [active]
1132507004169	putative active site [active]
1132507004170	putative substrate binding site [chemical binding]; other site
1132507004171	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1132507004172	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1132507004173	dimer interface [polypeptide binding]; other site
1132507004174	active site
1132507004175	metal binding site [ion binding]; metal-binding site
1132507004176	glutathione binding site [chemical binding]; other site
1132507004177	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1132507004178	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1132507004179	FMN binding site [chemical binding]; other site
1132507004180	active site
1132507004181	substrate binding site [chemical binding]; other site
1132507004182	catalytic residue [active]
1132507004183	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1132507004184	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507004185	Protein of unknown function (DUF1289); Region: DUF1289; cl01304
1132507004186	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1132507004187	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1132507004188	active site
1132507004189	catalytic tetrad [active]
1132507004190	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1132507004191	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1132507004192	E-class dimer interface [polypeptide binding]; other site
1132507004193	P-class dimer interface [polypeptide binding]; other site
1132507004194	active site
1132507004195	Cu2+ binding site [ion binding]; other site
1132507004196	Zn2+ binding site [ion binding]; other site
1132507004197	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1132507004198	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1132507004199	RNA polymerase Rpb4; Region: RNA_pol_Rpb4; cl00638
1132507004200	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1132507004201	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1132507004202	HlyD family secretion protein; Region: HlyD_3; pfam13437
1132507004203	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1132507004204	transcriptional regulator SlyA; Provisional; Region: PRK03573
1132507004205	MarR family; Region: MarR; pfam01047
1132507004206	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1132507004207	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1132507004208	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1132507004209	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1132507004210	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1132507004211	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1132507004212	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1132507004213	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1132507004214	active site
1132507004215	HIGH motif; other site
1132507004216	dimer interface [polypeptide binding]; other site
1132507004217	KMSKS motif; other site
1132507004218	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1132507004219	RNA binding surface [nucleotide binding]; other site
1132507004220	pyridoxamine kinase; Validated; Region: PRK05756
1132507004221	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1132507004222	dimer interface [polypeptide binding]; other site
1132507004223	pyridoxal binding site [chemical binding]; other site
1132507004224	ATP binding site [chemical binding]; other site
1132507004225	glutathionine S-transferase; Provisional; Region: PRK10542
1132507004226	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1132507004227	C-terminal domain interface [polypeptide binding]; other site
1132507004228	GSH binding site (G-site) [chemical binding]; other site
1132507004229	dimer interface [polypeptide binding]; other site
1132507004230	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1132507004231	dimer interface [polypeptide binding]; other site
1132507004232	N-terminal domain interface [polypeptide binding]; other site
1132507004233	substrate binding pocket (H-site) [chemical binding]; other site
1132507004234	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1132507004235	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507004236	putative substrate translocation pore; other site
1132507004237	POT family; Region: PTR2; pfam00854
1132507004238	endonuclease III; Provisional; Region: PRK10702
1132507004239	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1132507004240	minor groove reading motif; other site
1132507004241	helix-hairpin-helix signature motif; other site
1132507004242	substrate binding pocket [chemical binding]; other site
1132507004243	active site
1132507004244	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1132507004245	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1132507004246	electron transport complex protein RnfG; Validated; Region: PRK01908
1132507004247	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1132507004248	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1132507004249	SLBB domain; Region: SLBB; pfam10531
1132507004250	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1132507004251	electron transport complex protein RnfB; Provisional; Region: PRK05113
1132507004252	Putative Fe-S cluster; Region: FeS; cl17515
1132507004253	4Fe-4S binding domain; Region: Fer4; pfam00037
1132507004254	electron transport complex protein RsxA; Provisional; Region: PRK05151
1132507004255	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1132507004256	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1132507004257	putative oxidoreductase; Provisional; Region: PRK11579
1132507004258	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1132507004259	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1132507004260	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1132507004261	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1132507004262	active site
1132507004263	purine riboside binding site [chemical binding]; other site
1132507004264	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
1132507004265	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1132507004266	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1132507004267	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1132507004268	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1132507004269	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1132507004270	fumarate hydratase; Provisional; Region: PRK15389
1132507004271	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1132507004272	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1132507004273	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1132507004274	Class II fumarases; Region: Fumarase_classII; cd01362
1132507004275	active site
1132507004276	tetramer interface [polypeptide binding]; other site
1132507004277	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1132507004278	sensor protein RstB; Provisional; Region: PRK10604
1132507004279	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507004280	dimerization interface [polypeptide binding]; other site
1132507004281	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507004282	dimer interface [polypeptide binding]; other site
1132507004283	phosphorylation site [posttranslational modification]
1132507004284	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507004285	ATP binding site [chemical binding]; other site
1132507004286	Mg2+ binding site [ion binding]; other site
1132507004287	G-X-G motif; other site
1132507004288	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1132507004289	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1132507004290	active site
1132507004291	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1132507004292	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1132507004293	trimer interface [polypeptide binding]; other site
1132507004294	eyelet of channel; other site
1132507004295	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1132507004296	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507004297	active site
1132507004298	phosphorylation site [posttranslational modification]
1132507004299	intermolecular recognition site; other site
1132507004300	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507004301	DNA binding site [nucleotide binding]
1132507004302	GlpM protein; Region: GlpM; pfam06942
1132507004303	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1132507004304	Spore germination protein; Region: Spore_permease; cl17796
1132507004305	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1132507004306	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1132507004307	catalytic residues [active]
1132507004308	catalytic nucleophile [active]
1132507004309	Presynaptic Site I dimer interface [polypeptide binding]; other site
1132507004310	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1132507004311	Synaptic Flat tetramer interface [polypeptide binding]; other site
1132507004312	Synaptic Site I dimer interface [polypeptide binding]; other site
1132507004313	DNA binding site [nucleotide binding]
1132507004314	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1132507004315	DNA-binding interface [nucleotide binding]; DNA binding site
1132507004316	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1132507004317	Phage Tail Collar Domain; Region: Collar; pfam07484
1132507004318	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684
1132507004319	Baseplate J-like protein; Region: Baseplate_J; cl01294
1132507004320	Phage baseplate assembly protein W [General function prediction only]; Region: COG3628
1132507004321	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1132507004322	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1132507004323	Phage protein D [General function prediction only]; Region: COG3500
1132507004324	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1132507004325	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1132507004326	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1132507004327	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1132507004328	phage contractile tail tube protein, P2 family; Region: tail_tube; TIGR01611
1132507004329	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
1132507004330	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
1132507004331	Gp37 protein; Region: Gp37; pfam09646
1132507004332	Protein of unknown function (DUF1320); Region: DUF1320; pfam07030
1132507004333	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
1132507004334	Phage Mu protein F like protein; Region: Phage_Mu_F; pfam04233
1132507004335	Protein of unknown function (DUF935); Region: DUF935; pfam06074
1132507004336	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
1132507004337	Terminase-like family; Region: Terminase_6; pfam03237
1132507004338	Protein of unknown function (DUF3486); Region: DUF3486; pfam11985
1132507004339	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK06476
1132507004340	acetolactate synthase 3 catalytic subunit; Reviewed; Region: PRK06048
1132507004341	phage lambda Rz-like lysis protein; Region: PHA00276
1132507004342	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
1132507004343	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1132507004344	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1132507004345	catalytic residue [active]
1132507004346	Protein of unknown function (DUF4063); Region: DUF4063; pfam13272
1132507004347	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
1132507004348	Integrase core domain; Region: rve; pfam00665
1132507004349	Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]; Region: ExeA; COG3267
1132507004350	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507004351	Walker A/P-loop; other site
1132507004352	ATP binding site [chemical binding]; other site
1132507004353	Bacteriophage Mu Gam like protein; Region: Phage_Mu_Gam; cl01825
1132507004354	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u2; cd11539
1132507004355	metal binding site [ion binding]; metal-binding site
1132507004356	Protein of unknown function (DUF1018); Region: DUF1018; pfam06252
1132507004357	Mor transcription activator family; Region: Mor; pfam08765
1132507004358	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1132507004359	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1132507004360	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1132507004361	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1132507004362	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1132507004363	ligand binding site [chemical binding]; other site
1132507004364	homodimer interface [polypeptide binding]; other site
1132507004365	NAD(P) binding site [chemical binding]; other site
1132507004366	trimer interface B [polypeptide binding]; other site
1132507004367	trimer interface A [polypeptide binding]; other site
1132507004368	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1132507004369	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1132507004370	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1132507004371	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1132507004372	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1132507004373	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1132507004374	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1132507004375	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1132507004376	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507004377	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1132507004378	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507004379	putative substrate translocation pore; other site
1132507004380	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1132507004381	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507004382	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1132507004383	dimerization interface [polypeptide binding]; other site
1132507004384	substrate binding pocket [chemical binding]; other site
1132507004385	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1132507004386	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1132507004387	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1132507004388	nucleotide binding site [chemical binding]; other site
1132507004389	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1132507004390	AAA domain; Region: AAA_26; pfam13500
1132507004391	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1132507004392	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1132507004393	Cl- selectivity filter; other site
1132507004394	Cl- binding residues [ion binding]; other site
1132507004395	pore gating glutamate residue; other site
1132507004396	dimer interface [polypeptide binding]; other site
1132507004397	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1132507004398	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1132507004399	Walker A/P-loop; other site
1132507004400	ATP binding site [chemical binding]; other site
1132507004401	Q-loop/lid; other site
1132507004402	ABC transporter signature motif; other site
1132507004403	Walker B; other site
1132507004404	D-loop; other site
1132507004405	H-loop/switch region; other site
1132507004406	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
1132507004407	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507004408	dimer interface [polypeptide binding]; other site
1132507004409	conserved gate region; other site
1132507004410	ABC-ATPase subunit interface; other site
1132507004411	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1132507004412	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507004413	dimer interface [polypeptide binding]; other site
1132507004414	conserved gate region; other site
1132507004415	putative PBP binding loops; other site
1132507004416	ABC-ATPase subunit interface; other site
1132507004417	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1132507004418	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1132507004419	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1132507004420	4Fe-4S binding domain; Region: Fer4; pfam00037
1132507004421	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1132507004422	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1132507004423	putative [Fe4-S4] binding site [ion binding]; other site
1132507004424	putative molybdopterin cofactor binding site [chemical binding]; other site
1132507004425	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1132507004426	putative molybdopterin cofactor binding site; other site
1132507004427	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1132507004428	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1132507004429	putative [Fe4-S4] binding site [ion binding]; other site
1132507004430	putative molybdopterin cofactor binding site [chemical binding]; other site
1132507004431	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1132507004432	putative molybdopterin cofactor binding site; other site
1132507004433	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
1132507004434	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1132507004435	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507004436	Coenzyme A binding pocket [chemical binding]; other site
1132507004437	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1132507004438	hypothetical protein; Provisional; Region: PRK13659
1132507004439	hypothetical protein; Provisional; Region: PRK02237
1132507004440	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1132507004441	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1132507004442	putative active site pocket [active]
1132507004443	putative metal binding site [ion binding]; other site
1132507004444	putative oxidoreductase; Provisional; Region: PRK10083
1132507004445	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1132507004446	putative NAD(P) binding site [chemical binding]; other site
1132507004447	catalytic Zn binding site [ion binding]; other site
1132507004448	structural Zn binding site [ion binding]; other site
1132507004449	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507004450	metabolite-proton symporter; Region: 2A0106; TIGR00883
1132507004451	putative substrate translocation pore; other site
1132507004452	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
1132507004453	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1132507004454	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507004455	DNA-binding site [nucleotide binding]; DNA binding site
1132507004456	FCD domain; Region: FCD; pfam07729
1132507004457	malonic semialdehyde reductase; Provisional; Region: PRK10538
1132507004458	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1132507004459	putative NAD(P) binding site [chemical binding]; other site
1132507004460	homodimer interface [polypeptide binding]; other site
1132507004461	homotetramer interface [polypeptide binding]; other site
1132507004462	active site
1132507004463	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1132507004464	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1132507004465	active site
1132507004466	Zn binding site [ion binding]; other site
1132507004467	General stress protein [General function prediction only]; Region: GsiB; COG3729
1132507004468	hypothetical protein; Validated; Region: PRK03657
1132507004469	hypothetical protein; Provisional; Region: PRK10053
1132507004470	putative transporter; Provisional; Region: PRK10054
1132507004471	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507004472	putative substrate translocation pore; other site
1132507004473	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1132507004474	EamA-like transporter family; Region: EamA; pfam00892
1132507004475	MarB protein; Region: MarB; pfam13999
1132507004476	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
1132507004477	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507004478	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507004479	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
1132507004480	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1132507004481	inner membrane protein; Provisional; Region: PRK10995
1132507004482	putative arabinose transporter; Provisional; Region: PRK03545
1132507004483	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507004484	putative substrate translocation pore; other site
1132507004485	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507004486	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507004487	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1132507004488	putative dimerization interface [polypeptide binding]; other site
1132507004489	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
1132507004490	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1132507004491	NAD(P) binding site [chemical binding]; other site
1132507004492	catalytic residues [active]
1132507004493	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1132507004494	glutaminase; Provisional; Region: PRK00971
1132507004495	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1132507004496	Predicted membrane protein [Function unknown]; Region: COG3781
1132507004497	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1132507004498	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1132507004499	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1132507004500	trimer interface [polypeptide binding]; other site
1132507004501	eyelet of channel; other site
1132507004502	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1132507004503	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1132507004504	Rubredoxin [Energy production and conversion]; Region: COG1773
1132507004505	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1132507004506	iron binding site [ion binding]; other site
1132507004507	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1132507004508	HupF/HypC family; Region: HupF_HypC; cl00394
1132507004509	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1132507004510	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1132507004511	putative substrate-binding site; other site
1132507004512	nickel binding site [ion binding]; other site
1132507004513	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
1132507004514	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
1132507004515	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1132507004516	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1132507004517	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
1132507004518	active site
1132507004519	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1132507004520	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507004521	DNA-binding site [nucleotide binding]; DNA binding site
1132507004522	FCD domain; Region: FCD; pfam07729
1132507004523	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1132507004524	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1132507004525	putative NAD(P) binding site [chemical binding]; other site
1132507004526	catalytic Zn binding site [ion binding]; other site
1132507004527	structural Zn binding site [ion binding]; other site
1132507004528	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507004529	D-galactonate transporter; Region: 2A0114; TIGR00893
1132507004530	putative substrate translocation pore; other site
1132507004531	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
1132507004532	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507004533	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1132507004534	putative substrate translocation pore; other site
1132507004535	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1132507004536	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1132507004537	putative DNA binding site [nucleotide binding]; other site
1132507004538	putative Zn2+ binding site [ion binding]; other site
1132507004539	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
1132507004540	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1132507004541	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cl10015
1132507004542	homotrimer interaction site [polypeptide binding]; other site
1132507004543	putative active site [active]
1132507004544	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1132507004545	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507004546	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1132507004547	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507004548	homodimer interface [polypeptide binding]; other site
1132507004549	catalytic residue [active]
1132507004550	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1132507004551	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1132507004552	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1132507004553	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1132507004554	active site
1132507004555	catalytic site [active]
1132507004556	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
1132507004557	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1132507004558	active site
1132507004559	catalytic site [active]
1132507004560	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
1132507004561	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
1132507004562	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
1132507004563	catalytic site [active]
1132507004564	active site
1132507004565	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1132507004566	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
1132507004567	acid-resistance protein; Provisional; Region: hdeB; PRK11566
1132507004568	Haemolysin E (HlyE); Region: HlyE; cl11627
1132507004569	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1132507004570	biofilm-dependent modulation protein; Provisional; Region: PRK11436
1132507004571	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
1132507004572	malate dehydrogenase; Provisional; Region: PRK13529
1132507004573	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1132507004574	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1132507004575	NAD(P) binding site [chemical binding]; other site
1132507004576	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1132507004577	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1132507004578	NAD binding site [chemical binding]; other site
1132507004579	substrate binding site [chemical binding]; other site
1132507004580	catalytic Zn binding site [ion binding]; other site
1132507004581	tetramer interface [polypeptide binding]; other site
1132507004582	structural Zn binding site [ion binding]; other site
1132507004583	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1132507004584	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1132507004585	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1132507004586	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1132507004587	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1132507004588	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507004589	putative substrate translocation pore; other site
1132507004590	TetR family transcriptional regulator; Provisional; Region: PRK14996
1132507004591	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507004592	nitrite extrusion protein (nitrite facilitator); Region: 2A0108; TIGR00886
1132507004593	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1132507004594	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1132507004595	[4Fe-4S] binding site [ion binding]; other site
1132507004596	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1132507004597	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1132507004598	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1132507004599	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1132507004600	molybdopterin cofactor binding site; other site
1132507004601	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1132507004602	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1132507004603	hypothetical protein; Provisional; Region: PRK10281
1132507004604	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
1132507004605	L-asparagine permease; Provisional; Region: PRK15049
1132507004606	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1132507004607	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1132507004608	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1132507004609	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1132507004610	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1132507004611	N-terminal plug; other site
1132507004612	ligand-binding site [chemical binding]; other site
1132507004613	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
1132507004614	DNA-binding site [nucleotide binding]; DNA binding site
1132507004615	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1132507004616	FCD domain; Region: FCD; pfam07729
1132507004617	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1132507004618	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1132507004619	NAD(P) binding site [chemical binding]; other site
1132507004620	substrate binding site [chemical binding]; other site
1132507004621	dimer interface [polypeptide binding]; other site
1132507004622	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1132507004623	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1132507004624	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1132507004625	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1132507004626	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
1132507004627	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
1132507004628	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
1132507004629	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
1132507004630	tetrameric interface [polypeptide binding]; other site
1132507004631	NAD binding site [chemical binding]; other site
1132507004632	catalytic residues [active]
1132507004633	substrate binding site [chemical binding]; other site
1132507004634	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1132507004635	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507004636	DNA-binding site [nucleotide binding]; DNA binding site
1132507004637	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507004638	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507004639	homodimer interface [polypeptide binding]; other site
1132507004640	catalytic residue [active]
1132507004641	D-alanyl-D-alanine dipeptidase [Cell envelope biogenesis, outer membrane]; Region: DdpX; COG2173
1132507004642	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
1132507004643	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
1132507004644	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1132507004645	Peptidase family U32; Region: Peptidase_U32; pfam01136
1132507004646	Collagenase; Region: DUF3656; pfam12392
1132507004647	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1132507004648	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1132507004649	non-specific DNA binding site [nucleotide binding]; other site
1132507004650	salt bridge; other site
1132507004651	sequence-specific DNA binding site [nucleotide binding]; other site
1132507004652	Cupin domain; Region: Cupin_2; pfam07883
1132507004653	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
1132507004654	benzoate transporter; Region: benE; TIGR00843
1132507004655	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1132507004656	tellurite resistance protein TehB; Provisional; Region: PRK11207
1132507004657	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507004658	S-adenosylmethionine binding site [chemical binding]; other site
1132507004659	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1132507004660	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1132507004661	gating phenylalanine in ion channel; other site
1132507004662	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1132507004663	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1132507004664	putative trimer interface [polypeptide binding]; other site
1132507004665	putative CoA binding site [chemical binding]; other site
1132507004666	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1132507004667	putative trimer interface [polypeptide binding]; other site
1132507004668	putative CoA binding site [chemical binding]; other site
1132507004669	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1132507004670	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507004671	Coenzyme A binding pocket [chemical binding]; other site
1132507004672	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1132507004673	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1132507004674	oligomer interface [polypeptide binding]; other site
1132507004675	active site
1132507004676	metal binding site [ion binding]; metal-binding site
1132507004677	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1132507004678	active site
1132507004679	P-loop; other site
1132507004680	phosphorylation site [posttranslational modification]
1132507004681	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1132507004682	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
1132507004683	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
1132507004684	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1132507004685	active site
1132507004686	phosphorylation site [posttranslational modification]
1132507004687	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1132507004688	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1132507004689	substrate binding site [chemical binding]; other site
1132507004690	hexamer interface [polypeptide binding]; other site
1132507004691	metal binding site [ion binding]; metal-binding site
1132507004692	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1132507004693	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1132507004694	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507004695	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507004696	Coenzyme A binding pocket [chemical binding]; other site
1132507004697	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
1132507004698	teramer interface [polypeptide binding]; other site
1132507004699	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
1132507004700	active site
1132507004701	FMN binding site [chemical binding]; other site
1132507004702	catalytic residues [active]
1132507004703	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1132507004704	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1132507004705	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1132507004706	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1132507004707	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1132507004708	substrate binding pocket [chemical binding]; other site
1132507004709	catalytic triad [active]
1132507004710	Domain of unknown function (DUF1338); Region: DUF1338; pfam07063
1132507004711	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1132507004712	Predicted membrane protein [Function unknown]; Region: COG3326
1132507004713	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507004714	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1132507004715	substrate binding pocket [chemical binding]; other site
1132507004716	membrane-bound complex binding site; other site
1132507004717	hinge residues; other site
1132507004718	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1132507004719	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507004720	dimer interface [polypeptide binding]; other site
1132507004721	conserved gate region; other site
1132507004722	putative PBP binding loops; other site
1132507004723	ABC-ATPase subunit interface; other site
1132507004724	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1132507004725	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507004726	Walker A/P-loop; other site
1132507004727	ATP binding site [chemical binding]; other site
1132507004728	Q-loop/lid; other site
1132507004729	ABC transporter signature motif; other site
1132507004730	Walker B; other site
1132507004731	D-loop; other site
1132507004732	H-loop/switch region; other site
1132507004733	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1132507004734	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507004735	dimer interface [polypeptide binding]; other site
1132507004736	conserved gate region; other site
1132507004737	putative PBP binding loops; other site
1132507004738	ABC-ATPase subunit interface; other site
1132507004739	Predicted membrane protein [Function unknown]; Region: COG5305
1132507004740	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507004741	S-adenosylmethionine binding site [chemical binding]; other site
1132507004742	cytochrome b561; Provisional; Region: PRK11513
1132507004743	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1132507004744	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1132507004745	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1132507004746	putative active site [active]
1132507004747	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1132507004748	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507004749	ATP binding site [chemical binding]; other site
1132507004750	putative Mg++ binding site [ion binding]; other site
1132507004751	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507004752	nucleotide binding region [chemical binding]; other site
1132507004753	ATP-binding site [chemical binding]; other site
1132507004754	Helicase associated domain (HA2); Region: HA2; pfam04408
1132507004755	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1132507004756	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1132507004757	azoreductase; Reviewed; Region: PRK00170
1132507004758	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1132507004759	Glutathione-dependent formaldehyde-activating enzyme; Region: GFA; cl01553
1132507004760	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1132507004761	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1132507004762	hypothetical protein; Provisional; Region: PRK10695
1132507004763	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1132507004764	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1132507004765	putative ligand binding site [chemical binding]; other site
1132507004766	putative NAD binding site [chemical binding]; other site
1132507004767	catalytic site [active]
1132507004768	heat-inducible protein; Provisional; Region: PRK10449
1132507004769	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1132507004770	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1132507004771	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1132507004772	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1132507004773	dimer interface [polypeptide binding]; other site
1132507004774	PYR/PP interface [polypeptide binding]; other site
1132507004775	TPP binding site [chemical binding]; other site
1132507004776	substrate binding site [chemical binding]; other site
1132507004777	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1132507004778	Domain of unknown function; Region: EKR; smart00890
1132507004779	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1132507004780	4Fe-4S binding domain; Region: Fer4; pfam00037
1132507004781	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1132507004782	TPP-binding site [chemical binding]; other site
1132507004783	dimer interface [polypeptide binding]; other site
1132507004784	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507004785	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1132507004786	Ligand Binding Site [chemical binding]; other site
1132507004787	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1132507004788	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1132507004789	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1132507004790	Ligand Binding Site [chemical binding]; other site
1132507004791	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1132507004792	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1132507004793	ATP binding site [chemical binding]; other site
1132507004794	Mg++ binding site [ion binding]; other site
1132507004795	motif III; other site
1132507004796	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507004797	nucleotide binding region [chemical binding]; other site
1132507004798	ATP-binding site [chemical binding]; other site
1132507004799	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1132507004800	putative RNA binding site [nucleotide binding]; other site
1132507004801	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1132507004802	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1132507004803	Cl binding site [ion binding]; other site
1132507004804	oligomer interface [polypeptide binding]; other site
1132507004805	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1132507004806	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1132507004807	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1132507004808	dimer interface [polypeptide binding]; other site
1132507004809	putative CheW interface [polypeptide binding]; other site
1132507004810	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1132507004811	Smr domain; Region: Smr; pfam01713
1132507004812	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1132507004813	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1132507004814	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1132507004815	DNA binding site [nucleotide binding]
1132507004816	active site
1132507004817	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1132507004818	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1132507004819	ligand binding site [chemical binding]; other site
1132507004820	flexible hinge region; other site
1132507004821	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1132507004822	putative switch regulator; other site
1132507004823	non-specific DNA interactions [nucleotide binding]; other site
1132507004824	DNA binding site [nucleotide binding]
1132507004825	sequence specific DNA binding site [nucleotide binding]; other site
1132507004826	putative cAMP binding site [chemical binding]; other site
1132507004827	universal stress protein UspE; Provisional; Region: PRK11175
1132507004828	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1132507004829	Ligand Binding Site [chemical binding]; other site
1132507004830	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1132507004831	Ligand Binding Site [chemical binding]; other site
1132507004832	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1132507004833	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1132507004834	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1132507004835	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1132507004836	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1132507004837	non-specific DNA binding site [nucleotide binding]; other site
1132507004838	salt bridge; other site
1132507004839	sequence-specific DNA binding site [nucleotide binding]; other site
1132507004840	Cupin domain; Region: Cupin_2; pfam07883
1132507004841	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1132507004842	B3/4 domain; Region: B3_4; pfam03483
1132507004843	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: Tpx; COG2077
1132507004844	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1132507004845	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1132507004846	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507004847	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1132507004848	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1132507004849	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1132507004850	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507004851	oxidoreductase; Provisional; Region: PRK12742
1132507004852	classical (c) SDRs; Region: SDR_c; cd05233
1132507004853	NAD(P) binding site [chemical binding]; other site
1132507004854	active site
1132507004855	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1132507004856	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1132507004857	active site
1132507004858	catalytic tetrad [active]
1132507004859	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507004860	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507004861	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1132507004862	putative effector binding pocket; other site
1132507004863	putative dimerization interface [polypeptide binding]; other site
1132507004864	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
1132507004865	NmrA-like family; Region: NmrA; pfam05368
1132507004866	NAD(P) binding site [chemical binding]; other site
1132507004867	active site lysine
1132507004868	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1132507004869	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1132507004870	peptide binding site [polypeptide binding]; other site
1132507004871	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
1132507004872	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
1132507004873	putative active site [active]
1132507004874	Zn binding site [ion binding]; other site
1132507004875	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1132507004876	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1132507004877	active site
1132507004878	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1132507004879	dimer interface [polypeptide binding]; other site
1132507004880	catalytic triad [active]
1132507004881	peroxidatic and resolving cysteines [active]
1132507004882	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507004883	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1132507004884	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1132507004885	putative aromatic amino acid binding site; other site
1132507004886	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507004887	Walker A motif; other site
1132507004888	ATP binding site [chemical binding]; other site
1132507004889	Walker B motif; other site
1132507004890	arginine finger; other site
1132507004891	hypothetical protein; Provisional; Region: PRK05415
1132507004892	TIGR01620 family protein; Region: hyp_HI0043
1132507004893	Predicted ATPase [General function prediction only]; Region: COG3106
1132507004894	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1132507004895	active site residue [active]
1132507004896	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1132507004897	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1132507004898	phage shock protein C; Region: phageshock_pspC; TIGR02978
1132507004899	phage shock protein B; Provisional; Region: pspB; PRK09458
1132507004900	phage shock protein PspA; Provisional; Region: PRK10698
1132507004901	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1132507004902	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507004903	Walker A motif; other site
1132507004904	ATP binding site [chemical binding]; other site
1132507004905	Walker B motif; other site
1132507004906	arginine finger; other site
1132507004907	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1132507004908	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1132507004909	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1132507004910	peptide binding site [polypeptide binding]; other site
1132507004911	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1132507004912	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507004913	dimer interface [polypeptide binding]; other site
1132507004914	conserved gate region; other site
1132507004915	putative PBP binding loops; other site
1132507004916	ABC-ATPase subunit interface; other site
1132507004917	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1132507004918	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
1132507004919	Pertussis toxin, subunit 1; Region: Pertussis_S1; cl03779
1132507004920	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1132507004921	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1132507004922	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507004923	dimer interface [polypeptide binding]; other site
1132507004924	conserved gate region; other site
1132507004925	putative PBP binding loops; other site
1132507004926	ABC-ATPase subunit interface; other site
1132507004927	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1132507004928	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507004929	Walker A/P-loop; other site
1132507004930	ATP binding site [chemical binding]; other site
1132507004931	Q-loop/lid; other site
1132507004932	ABC transporter signature motif; other site
1132507004933	Walker B; other site
1132507004934	D-loop; other site
1132507004935	H-loop/switch region; other site
1132507004936	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1132507004937	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1132507004938	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507004939	Walker A/P-loop; other site
1132507004940	ATP binding site [chemical binding]; other site
1132507004941	Q-loop/lid; other site
1132507004942	ABC transporter signature motif; other site
1132507004943	Walker B; other site
1132507004944	D-loop; other site
1132507004945	H-loop/switch region; other site
1132507004946	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1132507004947	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1132507004948	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1132507004949	NAD binding site [chemical binding]; other site
1132507004950	homotetramer interface [polypeptide binding]; other site
1132507004951	homodimer interface [polypeptide binding]; other site
1132507004952	substrate binding site [chemical binding]; other site
1132507004953	active site
1132507004954	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
1132507004955	exoribonuclease II; Provisional; Region: PRK05054
1132507004956	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1132507004957	RNB domain; Region: RNB; pfam00773
1132507004958	S1 RNA binding domain; Region: S1; pfam00575
1132507004959	RNase II stability modulator; Provisional; Region: PRK10060
1132507004960	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1132507004961	putative active site [active]
1132507004962	heme pocket [chemical binding]; other site
1132507004963	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507004964	metal binding site [ion binding]; metal-binding site
1132507004965	active site
1132507004966	I-site; other site
1132507004967	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507004968	hypothetical protein; Provisional; Region: PRK13658
1132507004969	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1132507004970	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1132507004971	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507004972	lipoprotein; Provisional; Region: PRK10540
1132507004973	translation initiation factor Sui1; Validated; Region: PRK06824
1132507004974	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1132507004975	putative rRNA binding site [nucleotide binding]; other site
1132507004976	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1132507004977	active site
1132507004978	dimer interface [polypeptide binding]; other site
1132507004979	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1132507004980	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1132507004981	binding surface
1132507004982	TPR motif; other site
1132507004983	Predicted membrane protein [Function unknown]; Region: COG3771
1132507004984	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1132507004985	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1132507004986	active site
1132507004987	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1132507004988	dimerization interface [polypeptide binding]; other site
1132507004989	active site
1132507004990	aconitate hydratase; Validated; Region: PRK09277
1132507004991	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1132507004992	substrate binding site [chemical binding]; other site
1132507004993	ligand binding site [chemical binding]; other site
1132507004994	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1132507004995	substrate binding site [chemical binding]; other site
1132507004996	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1132507004997	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1132507004998	substrate binding site [chemical binding]; other site
1132507004999	putative dimerization interface [polypeptide binding]; other site
1132507005000	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1132507005001	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1132507005002	active site
1132507005003	interdomain interaction site; other site
1132507005004	putative metal-binding site [ion binding]; other site
1132507005005	nucleotide binding site [chemical binding]; other site
1132507005006	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1132507005007	domain I; other site
1132507005008	DNA binding groove [nucleotide binding]
1132507005009	phosphate binding site [ion binding]; other site
1132507005010	domain II; other site
1132507005011	domain III; other site
1132507005012	nucleotide binding site [chemical binding]; other site
1132507005013	catalytic site [active]
1132507005014	domain IV; other site
1132507005015	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1132507005016	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1132507005017	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1132507005018	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1132507005019	hypothetical protein; Provisional; Region: PRK11037
1132507005020	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1132507005021	putative inner membrane peptidase; Provisional; Region: PRK11778
1132507005022	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1132507005023	tandem repeat interface [polypeptide binding]; other site
1132507005024	oligomer interface [polypeptide binding]; other site
1132507005025	active site residues [active]
1132507005026	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1132507005027	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1132507005028	NADP binding site [chemical binding]; other site
1132507005029	homodimer interface [polypeptide binding]; other site
1132507005030	active site
1132507005031	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1132507005032	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
1132507005033	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1132507005034	homodimer interface [polypeptide binding]; other site
1132507005035	Walker A motif; other site
1132507005036	ATP binding site [chemical binding]; other site
1132507005037	hydroxycobalamin binding site [chemical binding]; other site
1132507005038	Walker B motif; other site
1132507005039	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1132507005040	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1132507005041	RNA binding surface [nucleotide binding]; other site
1132507005042	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1132507005043	probable active site [active]
1132507005044	hypothetical protein; Provisional; Region: PRK11630
1132507005045	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1132507005046	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1132507005047	active site
1132507005048	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1132507005049	anthranilate synthase component I; Provisional; Region: PRK13564
1132507005050	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1132507005051	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1132507005052	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
1132507005053	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1132507005054	glutamine binding [chemical binding]; other site
1132507005055	catalytic triad [active]
1132507005056	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1132507005057	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1132507005058	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1132507005059	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1132507005060	active site
1132507005061	product (indole) binding pocket [chemical binding]; other site
1132507005062	substrate (anthranilate) binding pocket [chemical binding]; other site
1132507005063	ribulose/triose binding site [chemical binding]; other site
1132507005064	phosphate binding site [ion binding]; other site
1132507005065	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1132507005066	active site
1132507005067	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1132507005068	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1132507005069	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507005070	catalytic residue [active]
1132507005071	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1132507005072	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1132507005073	substrate binding site [chemical binding]; other site
1132507005074	active site
1132507005075	catalytic residues [active]
1132507005076	heterodimer interface [polypeptide binding]; other site
1132507005077	General stress protein [General function prediction only]; Region: GsiB; COG3729
1132507005078	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
1132507005079	dimerization interface [polypeptide binding]; other site
1132507005080	metal binding site [ion binding]; metal-binding site
1132507005081	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1132507005082	dinuclear metal binding motif [ion binding]; other site
1132507005083	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1132507005084	dimanganese center [ion binding]; other site
1132507005085	outer membrane protein W; Provisional; Region: PRK10959
1132507005086	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1132507005087	hypothetical protein; Provisional; Region: PRK02868
1132507005088	intracellular septation protein A; Reviewed; Region: PRK00259
1132507005089	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1132507005090	transport protein TonB; Provisional; Region: PRK10819
1132507005091	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1132507005092	YciI-like protein; Reviewed; Region: PRK11370
1132507005093	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1132507005094	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1132507005095	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1132507005096	putative active site [active]
1132507005097	catalytic site [active]
1132507005098	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1132507005099	putative active site [active]
1132507005100	catalytic site [active]
1132507005101	dsDNA-mimic protein; Reviewed; Region: PRK05094
1132507005102	Ion transport protein; Region: Ion_trans; pfam00520
1132507005103	Ion channel; Region: Ion_trans_2; pfam07885
1132507005104	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1132507005105	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507005106	Walker A/P-loop; other site
1132507005107	ATP binding site [chemical binding]; other site
1132507005108	Q-loop/lid; other site
1132507005109	ABC transporter signature motif; other site
1132507005110	Walker B; other site
1132507005111	D-loop; other site
1132507005112	H-loop/switch region; other site
1132507005113	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1132507005114	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1132507005115	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507005116	Walker A/P-loop; other site
1132507005117	ATP binding site [chemical binding]; other site
1132507005118	Q-loop/lid; other site
1132507005119	ABC transporter signature motif; other site
1132507005120	Walker B; other site
1132507005121	D-loop; other site
1132507005122	H-loop/switch region; other site
1132507005123	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1132507005124	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1132507005125	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507005126	dimer interface [polypeptide binding]; other site
1132507005127	conserved gate region; other site
1132507005128	putative PBP binding loops; other site
1132507005129	ABC-ATPase subunit interface; other site
1132507005130	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1132507005131	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1132507005132	peptide binding site [polypeptide binding]; other site
1132507005133	hypothetical protein; Provisional; Region: PRK11111
1132507005134	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1132507005135	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1132507005136	putative catalytic cysteine [active]
1132507005137	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1132507005138	putative active site [active]
1132507005139	metal binding site [ion binding]; metal-binding site
1132507005140	thymidine kinase; Provisional; Region: PRK04296
1132507005141	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1132507005142	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1132507005143	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1132507005144	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1132507005145	active site
1132507005146	tetramer interface; other site
1132507005147	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507005148	active site
1132507005149	response regulator of RpoS; Provisional; Region: PRK10693
1132507005150	phosphorylation site [posttranslational modification]
1132507005151	intermolecular recognition site; other site
1132507005152	dimerization interface [polypeptide binding]; other site
1132507005153	hypothetical protein; Provisional; Region: PRK10279
1132507005154	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1132507005155	active site
1132507005156	nucleophile elbow; other site
1132507005157	hypothetical protein; Provisional; Region: PRK01617
1132507005158	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1132507005159	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1132507005160	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1132507005161	putative active site [active]
1132507005162	putative substrate binding site [chemical binding]; other site
1132507005163	putative cosubstrate binding site; other site
1132507005164	catalytic site [active]
1132507005165	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1132507005166	Sel1-like repeats; Region: SEL1; smart00671
1132507005167	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1132507005168	Sel1-like repeats; Region: SEL1; smart00671
1132507005169	Sel1-like repeats; Region: SEL1; smart00671
1132507005170	Sel1-like repeats; Region: SEL1; smart00671
1132507005171	Sel1-like repeats; Region: SEL1; smart00671
1132507005172	Sel1-like repeats; Region: SEL1; smart00671
1132507005173	Sel1-like repeats; Region: SEL1; smart00671
1132507005174	Sel1-like repeats; Region: SEL1; smart00671
1132507005175	Sel1-like repeats; Region: SEL1; smart00671
1132507005176	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1132507005177	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1132507005178	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1132507005179	4Fe-4S binding domain; Region: Fer4; cl02805
1132507005180	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1132507005181	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1132507005182	[4Fe-4S] binding site [ion binding]; other site
1132507005183	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1132507005184	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1132507005185	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1132507005186	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1132507005187	molybdopterin cofactor binding site; other site
1132507005188	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1132507005189	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1132507005190	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1132507005191	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507005192	dimerization interface [polypeptide binding]; other site
1132507005193	Histidine kinase; Region: HisKA_3; pfam07730
1132507005194	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507005195	ATP binding site [chemical binding]; other site
1132507005196	Mg2+ binding site [ion binding]; other site
1132507005197	G-X-G motif; other site
1132507005198	transcriptional regulator NarL; Provisional; Region: PRK10651
1132507005199	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507005200	active site
1132507005201	phosphorylation site [posttranslational modification]
1132507005202	intermolecular recognition site; other site
1132507005203	dimerization interface [polypeptide binding]; other site
1132507005204	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507005205	DNA binding residues [nucleotide binding]
1132507005206	dimerization interface [polypeptide binding]; other site
1132507005207	putative invasin; Provisional; Region: PRK10177
1132507005208	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1132507005209	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1132507005210	cation transport regulator; Reviewed; Region: chaB; PRK09582
1132507005211	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1132507005212	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1132507005213	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507005214	isocitrate dehydrogenase; Validated; Region: PRK07362
1132507005215	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1132507005216	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1132507005217	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1132507005218	probable active site [active]
1132507005219	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
1132507005220	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1132507005221	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1132507005222	nudix motif; other site
1132507005223	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1132507005224	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1132507005225	putative lysogenization regulator; Reviewed; Region: PRK00218
1132507005226	adenylosuccinate lyase; Provisional; Region: PRK09285
1132507005227	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1132507005228	tetramer interface [polypeptide binding]; other site
1132507005229	active site
1132507005230	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1132507005231	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507005232	active site
1132507005233	phosphorylation site [posttranslational modification]
1132507005234	intermolecular recognition site; other site
1132507005235	dimerization interface [polypeptide binding]; other site
1132507005236	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507005237	DNA binding site [nucleotide binding]
1132507005238	sensor protein PhoQ; Provisional; Region: PRK10815
1132507005239	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1132507005240	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1132507005241	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507005242	ATP binding site [chemical binding]; other site
1132507005243	Mg2+ binding site [ion binding]; other site
1132507005244	G-X-G motif; other site
1132507005245	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1132507005246	Cupin domain; Region: Cupin_2; cl17218
1132507005247	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1132507005248	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1132507005249	metal binding site [ion binding]; metal-binding site
1132507005250	dimer interface [polypeptide binding]; other site
1132507005251	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1132507005252	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507005253	Walker A/P-loop; other site
1132507005254	ATP binding site [chemical binding]; other site
1132507005255	Q-loop/lid; other site
1132507005256	ABC transporter signature motif; other site
1132507005257	Walker B; other site
1132507005258	D-loop; other site
1132507005259	H-loop/switch region; other site
1132507005260	TOBE domain; Region: TOBE_2; pfam08402
1132507005261	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1132507005262	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507005263	dimer interface [polypeptide binding]; other site
1132507005264	conserved gate region; other site
1132507005265	putative PBP binding loops; other site
1132507005266	ABC-ATPase subunit interface; other site
1132507005267	secreted effector protein SifA; Reviewed; Region: sifA; PRK09498
1132507005268	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1132507005269	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507005270	dimer interface [polypeptide binding]; other site
1132507005271	conserved gate region; other site
1132507005272	putative PBP binding loops; other site
1132507005273	ABC-ATPase subunit interface; other site
1132507005274	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1132507005275	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1132507005276	NAD-dependent deacetylase; Provisional; Region: PRK00481
1132507005277	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1132507005278	NAD+ binding site [chemical binding]; other site
1132507005279	substrate binding site [chemical binding]; other site
1132507005280	Zn binding site [ion binding]; other site
1132507005281	fructokinase; Reviewed; Region: PRK09557
1132507005282	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1132507005283	nucleotide binding site [chemical binding]; other site
1132507005284	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1132507005285	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1132507005286	FtsX-like permease family; Region: FtsX; pfam02687
1132507005287	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1132507005288	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1132507005289	Walker A/P-loop; other site
1132507005290	ATP binding site [chemical binding]; other site
1132507005291	Q-loop/lid; other site
1132507005292	ABC transporter signature motif; other site
1132507005293	Walker B; other site
1132507005294	D-loop; other site
1132507005295	H-loop/switch region; other site
1132507005296	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1132507005297	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1132507005298	FtsX-like permease family; Region: FtsX; pfam02687
1132507005299	transcription-repair coupling factor; Provisional; Region: PRK10689
1132507005300	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1132507005301	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507005302	ATP binding site [chemical binding]; other site
1132507005303	putative Mg++ binding site [ion binding]; other site
1132507005304	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507005305	nucleotide binding region [chemical binding]; other site
1132507005306	ATP-binding site [chemical binding]; other site
1132507005307	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1132507005308	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
1132507005309	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1132507005310	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1132507005311	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1132507005312	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1132507005313	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507005314	hypothetical protein; Provisional; Region: PRK11280
1132507005315	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1132507005316	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507005317	hypothetical protein; Provisional; Region: PRK04940
1132507005318	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1132507005319	beta-hexosaminidase; Provisional; Region: PRK05337
1132507005320	thiamine kinase; Region: ycfN_thiK; TIGR02721
1132507005321	thiamine kinase; Provisional; Region: thiK; PRK10271
1132507005322	substrate binding site [chemical binding]; other site
1132507005323	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1132507005324	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1132507005325	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1132507005326	putative dimer interface [polypeptide binding]; other site
1132507005327	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1132507005328	nucleotide binding site/active site [active]
1132507005329	HIT family signature motif; other site
1132507005330	catalytic residue [active]
1132507005331	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1132507005332	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1132507005333	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1132507005334	active site turn [active]
1132507005335	phosphorylation site [posttranslational modification]
1132507005336	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1132507005337	active site
1132507005338	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1132507005339	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1132507005340	thymidylate kinase; Validated; Region: tmk; PRK00698
1132507005341	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1132507005342	TMP-binding site; other site
1132507005343	ATP-binding site [chemical binding]; other site
1132507005344	conserved hypothetical protein, YceG family; Region: TIGR00247
1132507005345	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1132507005346	dimerization interface [polypeptide binding]; other site
1132507005347	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1132507005348	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1132507005349	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507005350	catalytic residue [active]
1132507005351	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1132507005352	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1132507005353	dimer interface [polypeptide binding]; other site
1132507005354	active site
1132507005355	acyl carrier protein; Provisional; Region: acpP; PRK00982
1132507005356	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1132507005357	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1132507005358	NAD(P) binding site [chemical binding]; other site
1132507005359	homotetramer interface [polypeptide binding]; other site
1132507005360	homodimer interface [polypeptide binding]; other site
1132507005361	active site
1132507005362	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1132507005363	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1132507005364	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1132507005365	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1132507005366	dimer interface [polypeptide binding]; other site
1132507005367	active site
1132507005368	CoA binding pocket [chemical binding]; other site
1132507005369	putative phosphate acyltransferase; Provisional; Region: PRK05331
1132507005370	hypothetical protein; Provisional; Region: PRK11193
1132507005371	Maf-like protein; Region: Maf; pfam02545
1132507005372	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1132507005373	active site
1132507005374	dimer interface [polypeptide binding]; other site
1132507005375	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1132507005376	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1132507005377	RNA binding surface [nucleotide binding]; other site
1132507005378	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1132507005379	active site
1132507005380	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1132507005381	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1132507005382	homodimer interface [polypeptide binding]; other site
1132507005383	oligonucleotide binding site [chemical binding]; other site
1132507005384	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1132507005385	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507005386	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1132507005387	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1132507005388	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1132507005389	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1132507005390	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1132507005391	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1132507005392	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1132507005393	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1132507005394	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1132507005395	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1132507005396	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1132507005397	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1132507005398	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1132507005399	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1132507005400	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1132507005401	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1132507005402	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1132507005403	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1132507005404	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1132507005405	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1132507005406	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1132507005407	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
1132507005408	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1132507005409	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1132507005410	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1132507005411	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1132507005412	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1132507005413	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1132507005414	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1132507005415	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
1132507005416	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1132507005417	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1132507005418	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
1132507005419	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
1132507005420	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1132507005421	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1132507005422	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1132507005423	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1132507005424	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1132507005425	hypothetical protein; Provisional; Region: PRK11239
1132507005426	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1132507005427	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1132507005428	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1132507005429	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1132507005430	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507005431	putative substrate translocation pore; other site
1132507005432	glutaredoxin 2; Provisional; Region: PRK10387
1132507005433	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1132507005434	C-terminal domain interface [polypeptide binding]; other site
1132507005435	GSH binding site (G-site) [chemical binding]; other site
1132507005436	catalytic residues [active]
1132507005437	putative dimer interface [polypeptide binding]; other site
1132507005438	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1132507005439	N-terminal domain interface [polypeptide binding]; other site
1132507005440	lipoprotein; Provisional; Region: PRK10598
1132507005441	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1132507005442	active site
1132507005443	substrate binding pocket [chemical binding]; other site
1132507005444	dimer interface [polypeptide binding]; other site
1132507005445	DNA damage-inducible protein I; Provisional; Region: PRK10597
1132507005446	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1132507005447	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1132507005448	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1132507005449	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
1132507005450	hypothetical protein; Provisional; Region: PRK03757
1132507005451	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1132507005452	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1132507005453	active site residue [active]
1132507005454	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1132507005455	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1132507005456	putative acyl-acceptor binding pocket; other site
1132507005457	drug efflux system protein MdtG; Provisional; Region: PRK09874
1132507005458	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507005459	putative substrate translocation pore; other site
1132507005460	secY/secA suppressor protein; Provisional; Region: PRK11467
1132507005461	lipoprotein; Provisional; Region: PRK10175
1132507005462	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1132507005463	Ligand binding site; other site
1132507005464	DXD motif; other site
1132507005465	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1132507005466	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
1132507005467	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1132507005468	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1132507005469	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1132507005470	PLD-like domain; Region: PLDc_2; pfam13091
1132507005471	putative active site [active]
1132507005472	catalytic site [active]
1132507005473	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1132507005474	PLD-like domain; Region: PLDc_2; pfam13091
1132507005475	putative active site [active]
1132507005476	catalytic site [active]
1132507005477	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1132507005478	putative ADP-ribose binding site [chemical binding]; other site
1132507005479	putative active site [active]
1132507005480	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1132507005481	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
1132507005482	major curlin subunit; Provisional; Region: csgA; PRK10051
1132507005483	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1132507005484	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1132507005485	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1132507005486	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1132507005487	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1132507005488	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507005489	DNA binding residues [nucleotide binding]
1132507005490	dimerization interface [polypeptide binding]; other site
1132507005491	curli assembly protein CsgE; Provisional; Region: PRK10386
1132507005492	curli assembly protein CsgF; Provisional; Region: PRK10050
1132507005493	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
1132507005494	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1132507005495	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1132507005496	putative hydrolase; Validated; Region: PRK09248
1132507005497	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1132507005498	active site
1132507005499	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1132507005500	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1132507005501	putative ligand binding site [chemical binding]; other site
1132507005502	NAD binding site [chemical binding]; other site
1132507005503	dimerization interface [polypeptide binding]; other site
1132507005504	catalytic site [active]
1132507005505	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1132507005506	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1132507005507	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1132507005508	putative sialic acid transporter; Provisional; Region: PRK12307
1132507005509	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507005510	putative substrate translocation pore; other site
1132507005511	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1132507005512	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
1132507005513	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
1132507005514	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
1132507005515	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1132507005516	putative active site cavity [active]
1132507005517	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1132507005518	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1132507005519	Na binding site [ion binding]; other site
1132507005520	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1132507005521	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1132507005522	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1132507005523	putative active site [active]
1132507005524	hypothetical protein; Provisional; Region: PRK10536
1132507005525	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1132507005526	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1132507005527	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1132507005528	Na binding site [ion binding]; other site
1132507005529	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1132507005530	Predicted transcriptional regulator [Transcription]; Region: COG3905
1132507005531	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1132507005532	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1132507005533	Glutamate binding site [chemical binding]; other site
1132507005534	NAD binding site [chemical binding]; other site
1132507005535	catalytic residues [active]
1132507005536	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1132507005537	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1132507005538	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507005539	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1132507005540	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1132507005541	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1132507005542	hypothetical protein; Provisional; Region: PRK10174
1132507005543	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1132507005544	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1132507005545	catalytic core [active]
1132507005546	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1132507005547	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1132507005548	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1132507005549	catalytic residues [active]
1132507005550	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1132507005551	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1132507005552	catalytic residues [active]
1132507005553	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
1132507005554	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1132507005555	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1132507005556	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1132507005557	DsbD alpha interface [polypeptide binding]; other site
1132507005558	catalytic residues [active]
1132507005559	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
1132507005560	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1132507005561	HSP70 interaction site [polypeptide binding]; other site
1132507005562	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1132507005563	substrate binding site [polypeptide binding]; other site
1132507005564	dimer interface [polypeptide binding]; other site
1132507005565	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
1132507005566	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
1132507005567	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
1132507005568	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
1132507005569	Cupin domain; Region: Cupin_2; pfam07883
1132507005570	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507005571	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507005572	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1132507005573	putative substrate translocation pore; other site
1132507005574	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1132507005575	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
1132507005576	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
1132507005577	putative substrate binding pocket [chemical binding]; other site
1132507005578	trimer interface [polypeptide binding]; other site
1132507005579	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
1132507005580	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1132507005581	putative active site [active]
1132507005582	putative metal binding site [ion binding]; other site
1132507005583	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
1132507005584	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1132507005585	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1132507005586	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1132507005587	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1132507005588	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
1132507005589	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1132507005590	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
1132507005591	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1132507005592	active site
1132507005593	homotetramer interface [polypeptide binding]; other site
1132507005594	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
1132507005595	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507005596	active site
1132507005597	phosphorylation site [posttranslational modification]
1132507005598	intermolecular recognition site; other site
1132507005599	dimerization interface [polypeptide binding]; other site
1132507005600	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507005601	DNA binding site [nucleotide binding]
1132507005602	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1132507005603	HAMP domain; Region: HAMP; pfam00672
1132507005604	dimerization interface [polypeptide binding]; other site
1132507005605	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507005606	dimer interface [polypeptide binding]; other site
1132507005607	phosphorylation site [posttranslational modification]
1132507005608	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507005609	ATP binding site [chemical binding]; other site
1132507005610	Mg2+ binding site [ion binding]; other site
1132507005611	G-X-G motif; other site
1132507005612	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
1132507005613	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
1132507005614	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
1132507005615	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
1132507005616	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
1132507005617	secreted effector protein PipB; Provisional; Region: PRK15197
1132507005618	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1132507005619	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1132507005620	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1132507005621	PipA protein; Region: PipA; pfam07108
1132507005622	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507005623	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1132507005624	YccA-like proteins; Region: YccA_like; cd10433
1132507005625	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1132507005626	sulfur transfer protein TusE; Provisional; Region: PRK11508
1132507005627	acylphosphatase; Provisional; Region: PRK14426
1132507005628	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1132507005629	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507005630	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507005631	Cupin domain; Region: Cupin_2; cl17218
1132507005632	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1132507005633	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1132507005634	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1132507005635	putative RNA binding site [nucleotide binding]; other site
1132507005636	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507005637	S-adenosylmethionine binding site [chemical binding]; other site
1132507005638	heat shock protein HspQ; Provisional; Region: PRK14129
1132507005639	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1132507005640	hypothetical protein; Provisional; Region: PRK03641
1132507005641	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
1132507005642	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1132507005643	active site
1132507005644	dimer interfaces [polypeptide binding]; other site
1132507005645	catalytic residues [active]
1132507005646	DNA helicase IV; Provisional; Region: helD; PRK11054
1132507005647	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1132507005648	Part of AAA domain; Region: AAA_19; pfam13245
1132507005649	Family description; Region: UvrD_C_2; pfam13538
1132507005650	Predicted membrane protein [Function unknown]; Region: COG3304
1132507005651	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1132507005652	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1132507005653	TIGR01666 family membrane protein; Region: YCCS
1132507005654	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1132507005655	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1132507005656	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
1132507005657	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1132507005658	cell division inhibitor SulA; Region: sula; TIGR00623
1132507005659	outer membrane protein A; Reviewed; Region: PRK10808
1132507005660	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1132507005661	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1132507005662	ligand binding site [chemical binding]; other site
1132507005663	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1132507005664	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1132507005665	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1132507005666	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1132507005667	active site 1 [active]
1132507005668	dimer interface [polypeptide binding]; other site
1132507005669	active site 2 [active]
1132507005670	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1132507005671	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1132507005672	paraquat-inducible protein B; Provisional; Region: PRK10807
1132507005673	mce related protein; Region: MCE; pfam02470
1132507005674	mce related protein; Region: MCE; pfam02470
1132507005675	mce related protein; Region: MCE; pfam02470
1132507005676	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1132507005677	Paraquat-inducible protein A; Region: PqiA; pfam04403
1132507005678	Paraquat-inducible protein A; Region: PqiA; pfam04403
1132507005679	ABC transporter ATPase component; Reviewed; Region: PRK11147
1132507005680	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507005681	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507005682	Walker A/P-loop; other site
1132507005683	Walker A/P-loop; other site
1132507005684	ATP binding site [chemical binding]; other site
1132507005685	ATP binding site [chemical binding]; other site
1132507005686	Q-loop/lid; other site
1132507005687	Q-loop/lid; other site
1132507005688	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1132507005689	ABC transporter signature motif; other site
1132507005690	Walker B; other site
1132507005691	D-loop; other site
1132507005692	ABC transporter; Region: ABC_tran_2; pfam12848
1132507005693	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1132507005694	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1132507005695	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1132507005696	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1132507005697	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507005698	S-adenosylmethionine binding site [chemical binding]; other site
1132507005699	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1132507005700	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1132507005701	MOSC domain; Region: MOSC; pfam03473
1132507005702	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1132507005703	catalytic loop [active]
1132507005704	iron binding site [ion binding]; other site
1132507005705	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1132507005706	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1132507005707	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1132507005708	quinone interaction residues [chemical binding]; other site
1132507005709	active site
1132507005710	catalytic residues [active]
1132507005711	FMN binding site [chemical binding]; other site
1132507005712	substrate binding site [chemical binding]; other site
1132507005713	aminopeptidase N; Provisional; Region: pepN; PRK14015
1132507005714	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1132507005715	active site
1132507005716	Zn binding site [ion binding]; other site
1132507005717	DinI-like family; Region: DinI; cl11630
1132507005718	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1132507005719	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1132507005720	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
1132507005721	Baseplate J-like protein; Region: Baseplate_J; cl01294
1132507005722	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1132507005723	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1132507005724	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
1132507005725	virion protein; Provisional; Region: V; PHA02564
1132507005726	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
1132507005727	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
1132507005728	Protein of unknown function (DUF4054); Region: DUF4054; pfam13262
1132507005729	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834
1132507005730	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
1132507005731	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
1132507005732	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
1132507005733	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
1132507005734	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
1132507005735	Phage terminase large subunit; Region: Terminase_3; cl12054
1132507005736	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
1132507005737	Predicted chitinase [General function prediction only]; Region: COG3179
1132507005738	Protein of unknown function (DUF754); Region: DUF754; pfam05449
1132507005739	Antitermination protein; Region: Antiterm; pfam03589
1132507005740	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1132507005741	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1132507005742	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1132507005743	DinI-like family; Region: DinI; pfam06183
1132507005744	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
1132507005745	Protein of unknown function (DUF550); Region: DUF550; pfam04447
1132507005746	Methyltransferase domain; Region: Methyltransf_25; pfam13649
1132507005747	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1132507005748	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1132507005749	putative replication protein; Provisional; Region: PRK12377
1132507005750	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507005751	Walker A motif; other site
1132507005752	ATP binding site [chemical binding]; other site
1132507005753	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1132507005754	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1132507005755	primosomal protein DnaI; Provisional; Region: PRK02854
1132507005756	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
1132507005757	phage recombination protein Bet; Region: bet_lambda; TIGR01913
1132507005758	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1132507005759	DNA-sulfur modification-associated; Region: DndB; pfam14072
1132507005760	DGQHR domain; Region: DGQHR; TIGR03187
1132507005761	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1132507005762	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1132507005763	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1132507005764	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1132507005765	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
1132507005766	Int/Topo IB signature motif; other site
1132507005767	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1132507005768	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1132507005769	active site
1132507005770	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1132507005771	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1132507005772	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1132507005773	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1132507005774	putative DNA binding site [nucleotide binding]; other site
1132507005775	putative Zn2+ binding site [ion binding]; other site
1132507005776	AsnC family; Region: AsnC_trans_reg; pfam01037
1132507005777	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1132507005778	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1132507005779	putative dimer interface [polypeptide binding]; other site
1132507005780	putative anticodon binding site; other site
1132507005781	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1132507005782	homodimer interface [polypeptide binding]; other site
1132507005783	motif 1; other site
1132507005784	motif 2; other site
1132507005785	active site
1132507005786	motif 3; other site
1132507005787	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1132507005788	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1132507005789	trimer interface [polypeptide binding]; other site
1132507005790	eyelet of channel; other site
1132507005791	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1132507005792	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507005793	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507005794	homodimer interface [polypeptide binding]; other site
1132507005795	catalytic residue [active]
1132507005796	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1132507005797	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1132507005798	Peptidase M15; Region: Peptidase_M15_3; cl01194
1132507005799	murein L,D-transpeptidase; Provisional; Region: PRK10594
1132507005800	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1132507005801	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1132507005802	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1132507005803	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
1132507005804	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1132507005805	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1132507005806	condesin subunit E; Provisional; Region: PRK05256
1132507005807	condesin subunit F; Provisional; Region: PRK05260
1132507005808	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1132507005809	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507005810	S-adenosylmethionine binding site [chemical binding]; other site
1132507005811	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1132507005812	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1132507005813	putative active site [active]
1132507005814	hypothetical protein; Provisional; Region: PRK10593
1132507005815	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1132507005816	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1132507005817	Ligand binding site; other site
1132507005818	oligomer interface; other site
1132507005819	hypothetical protein; Provisional; Region: PRK11827
1132507005820	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1132507005821	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1132507005822	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1132507005823	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1132507005824	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1132507005825	Walker A/P-loop; other site
1132507005826	ATP binding site [chemical binding]; other site
1132507005827	Q-loop/lid; other site
1132507005828	ABC transporter signature motif; other site
1132507005829	Walker B; other site
1132507005830	D-loop; other site
1132507005831	H-loop/switch region; other site
1132507005832	ComEC family competence protein; Provisional; Region: PRK11539
1132507005833	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1132507005834	Competence protein; Region: Competence; pfam03772
1132507005835	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1132507005836	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1132507005837	IHF dimer interface [polypeptide binding]; other site
1132507005838	IHF - DNA interface [nucleotide binding]; other site
1132507005839	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1132507005840	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1132507005841	RNA binding site [nucleotide binding]; other site
1132507005842	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1132507005843	RNA binding site [nucleotide binding]; other site
1132507005844	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1132507005845	RNA binding site [nucleotide binding]; other site
1132507005846	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1132507005847	RNA binding site [nucleotide binding]; other site
1132507005848	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1132507005849	RNA binding site [nucleotide binding]; other site
1132507005850	cytidylate kinase; Provisional; Region: cmk; PRK00023
1132507005851	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1132507005852	CMP-binding site; other site
1132507005853	The sites determining sugar specificity; other site
1132507005854	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1132507005855	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1132507005856	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
1132507005857	hinge; other site
1132507005858	active site
1132507005859	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1132507005860	homodimer interface [polypeptide binding]; other site
1132507005861	substrate-cofactor binding pocket; other site
1132507005862	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507005863	catalytic residue [active]
1132507005864	Predicted membrane protein [Function unknown]; Region: COG2323
1132507005865	uncharacterized domain; Region: TIGR00702
1132507005866	YcaO-like family; Region: YcaO; pfam02624
1132507005867	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1132507005868	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1132507005869	Pyruvate formate lyase 1; Region: PFL1; cd01678
1132507005870	coenzyme A binding site [chemical binding]; other site
1132507005871	active site
1132507005872	catalytic residues [active]
1132507005873	glycine loop; other site
1132507005874	Salmonella outer protein D; Region: SopD; cl14701
1132507005875	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1132507005876	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507005877	FeS/SAM binding site; other site
1132507005878	inner membrane transporter YjeM; Provisional; Region: PRK15238
1132507005879	putative MFS family transporter protein; Provisional; Region: PRK03633
1132507005880	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507005881	putative substrate translocation pore; other site
1132507005882	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1132507005883	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1132507005884	4Fe-4S binding domain; Region: Fer4; pfam00037
1132507005885	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1132507005886	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1132507005887	putative [Fe4-S4] binding site [ion binding]; other site
1132507005888	putative molybdopterin cofactor binding site [chemical binding]; other site
1132507005889	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1132507005890	putative molybdopterin cofactor binding site; other site
1132507005891	seryl-tRNA synthetase; Provisional; Region: PRK05431
1132507005892	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1132507005893	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1132507005894	dimer interface [polypeptide binding]; other site
1132507005895	active site
1132507005896	motif 1; other site
1132507005897	motif 2; other site
1132507005898	motif 3; other site
1132507005899	recombination factor protein RarA; Reviewed; Region: PRK13342
1132507005900	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507005901	Walker A motif; other site
1132507005902	ATP binding site [chemical binding]; other site
1132507005903	Walker B motif; other site
1132507005904	arginine finger; other site
1132507005905	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1132507005906	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1132507005907	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1132507005908	DNA translocase FtsK; Provisional; Region: PRK10263
1132507005909	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1132507005910	DNA translocase FtsK; Provisional; Region: PRK10263
1132507005911	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1132507005912	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1132507005913	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1132507005914	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1132507005915	putative DNA binding site [nucleotide binding]; other site
1132507005916	putative Zn2+ binding site [ion binding]; other site
1132507005917	AsnC family; Region: AsnC_trans_reg; pfam01037
1132507005918	thioredoxin reductase; Provisional; Region: PRK10262
1132507005919	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1132507005920	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507005921	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1132507005922	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1132507005923	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507005924	Walker A/P-loop; other site
1132507005925	ATP binding site [chemical binding]; other site
1132507005926	Q-loop/lid; other site
1132507005927	ABC transporter signature motif; other site
1132507005928	Walker B; other site
1132507005929	D-loop; other site
1132507005930	H-loop/switch region; other site
1132507005931	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1132507005932	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1132507005933	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507005934	Walker A/P-loop; other site
1132507005935	ATP binding site [chemical binding]; other site
1132507005936	Q-loop/lid; other site
1132507005937	ABC transporter signature motif; other site
1132507005938	Walker B; other site
1132507005939	D-loop; other site
1132507005940	H-loop/switch region; other site
1132507005941	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1132507005942	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1132507005943	rRNA binding site [nucleotide binding]; other site
1132507005944	predicted 30S ribosome binding site; other site
1132507005945	LysR family transcriptional regulator; Provisional; Region: PRK14997
1132507005946	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507005947	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
1132507005948	putative effector binding pocket; other site
1132507005949	putative dimerization interface [polypeptide binding]; other site
1132507005950	Pirin-related protein [General function prediction only]; Region: COG1741
1132507005951	Pirin; Region: Pirin; pfam02678
1132507005952	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1132507005953	Isochorismatase family; Region: Isochorismatase; pfam00857
1132507005954	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1132507005955	catalytic triad [active]
1132507005956	dimer interface [polypeptide binding]; other site
1132507005957	conserved cis-peptide bond; other site
1132507005958	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1132507005959	DNA binding site [nucleotide binding]
1132507005960	active site
1132507005961	Int/Topo IB signature motif; other site
1132507005962	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1132507005963	Clp amino terminal domain; Region: Clp_N; pfam02861
1132507005964	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507005965	Walker A motif; other site
1132507005966	ATP binding site [chemical binding]; other site
1132507005967	Walker B motif; other site
1132507005968	arginine finger; other site
1132507005969	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507005970	Walker A motif; other site
1132507005971	ATP binding site [chemical binding]; other site
1132507005972	Walker B motif; other site
1132507005973	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1132507005974	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1132507005975	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1132507005976	DNA-binding site [nucleotide binding]; DNA binding site
1132507005977	RNA-binding motif; other site
1132507005978	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1132507005979	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1132507005980	Walker A/P-loop; other site
1132507005981	ATP binding site [chemical binding]; other site
1132507005982	Q-loop/lid; other site
1132507005983	ABC transporter signature motif; other site
1132507005984	Walker B; other site
1132507005985	D-loop; other site
1132507005986	H-loop/switch region; other site
1132507005987	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1132507005988	FtsX-like permease family; Region: FtsX; pfam02687
1132507005989	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1132507005990	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1132507005991	HlyD family secretion protein; Region: HlyD_3; pfam13437
1132507005992	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
1132507005993	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1132507005994	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1132507005995	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1132507005996	putative active site [active]
1132507005997	putative metal-binding site [ion binding]; other site
1132507005998	Predicted membrane protein [Function unknown]; Region: COG2431
1132507005999	hybrid cluster protein; Provisional; Region: PRK05290
1132507006000	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1132507006001	ACS interaction site; other site
1132507006002	CODH interaction site; other site
1132507006003	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1132507006004	hybrid metal cluster; other site
1132507006005	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1132507006006	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1132507006007	FAD binding pocket [chemical binding]; other site
1132507006008	FAD binding motif [chemical binding]; other site
1132507006009	phosphate binding motif [ion binding]; other site
1132507006010	beta-alpha-beta structure motif; other site
1132507006011	NAD binding pocket [chemical binding]; other site
1132507006012	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1132507006013	catalytic loop [active]
1132507006014	iron binding site [ion binding]; other site
1132507006015	pyruvate dehydrogenase; Provisional; Region: PRK09124
1132507006016	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1132507006017	PYR/PP interface [polypeptide binding]; other site
1132507006018	dimer interface [polypeptide binding]; other site
1132507006019	tetramer interface [polypeptide binding]; other site
1132507006020	TPP binding site [chemical binding]; other site
1132507006021	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1132507006022	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1132507006023	TPP-binding site [chemical binding]; other site
1132507006024	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1132507006025	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1132507006026	tetramer interface [polypeptide binding]; other site
1132507006027	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507006028	catalytic residue [active]
1132507006029	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1132507006030	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1132507006031	putative NAD(P) binding site [chemical binding]; other site
1132507006032	putative active site [active]
1132507006033	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1132507006034	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1132507006035	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1132507006036	NAD(P) binding site [chemical binding]; other site
1132507006037	active site
1132507006038	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1132507006039	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1132507006040	amidase catalytic site [active]
1132507006041	Zn binding residues [ion binding]; other site
1132507006042	substrate binding site [chemical binding]; other site
1132507006043	hypothetical protein; Provisional; Region: PRK02877
1132507006044	putative lipoprotein; Provisional; Region: PRK10533
1132507006045	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1132507006046	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507006047	Walker A/P-loop; other site
1132507006048	ATP binding site [chemical binding]; other site
1132507006049	Q-loop/lid; other site
1132507006050	ABC transporter signature motif; other site
1132507006051	Walker B; other site
1132507006052	D-loop; other site
1132507006053	H-loop/switch region; other site
1132507006054	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1132507006055	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507006056	substrate binding pocket [chemical binding]; other site
1132507006057	membrane-bound complex binding site; other site
1132507006058	hinge residues; other site
1132507006059	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1132507006060	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507006061	dimer interface [polypeptide binding]; other site
1132507006062	conserved gate region; other site
1132507006063	putative PBP binding loops; other site
1132507006064	ABC-ATPase subunit interface; other site
1132507006065	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507006066	dimer interface [polypeptide binding]; other site
1132507006067	conserved gate region; other site
1132507006068	putative PBP binding loops; other site
1132507006069	ABC-ATPase subunit interface; other site
1132507006070	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1132507006071	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507006072	substrate binding pocket [chemical binding]; other site
1132507006073	membrane-bound complex binding site; other site
1132507006074	hinge residues; other site
1132507006075	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1132507006076	Sulfatase; Region: Sulfatase; cl17466
1132507006077	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1132507006078	active site
1132507006079	P-loop; other site
1132507006080	phosphorylation site [posttranslational modification]
1132507006081	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1132507006082	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1132507006083	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507006084	S-adenosylmethionine binding site [chemical binding]; other site
1132507006085	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1132507006086	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1132507006087	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507006088	dimer interface [polypeptide binding]; other site
1132507006089	conserved gate region; other site
1132507006090	putative PBP binding loops; other site
1132507006091	ABC-ATPase subunit interface; other site
1132507006092	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507006093	dimer interface [polypeptide binding]; other site
1132507006094	conserved gate region; other site
1132507006095	putative PBP binding loops; other site
1132507006096	ABC-ATPase subunit interface; other site
1132507006097	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1132507006098	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507006099	Walker A/P-loop; other site
1132507006100	ATP binding site [chemical binding]; other site
1132507006101	Q-loop/lid; other site
1132507006102	ABC transporter signature motif; other site
1132507006103	Walker B; other site
1132507006104	D-loop; other site
1132507006105	H-loop/switch region; other site
1132507006106	TOBE domain; Region: TOBE_2; pfam08402
1132507006107	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1132507006108	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1132507006109	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1132507006110	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1132507006111	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1132507006112	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1132507006113	dimer interface [polypeptide binding]; other site
1132507006114	FMN binding site [chemical binding]; other site
1132507006115	NADPH bind site [chemical binding]; other site
1132507006116	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
1132507006117	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1132507006118	GSH binding site [chemical binding]; other site
1132507006119	catalytic residues [active]
1132507006120	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1132507006121	putative transporter; Provisional; Region: PRK04972
1132507006122	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1132507006123	TrkA-C domain; Region: TrkA_C; pfam02080
1132507006124	TrkA-C domain; Region: TrkA_C; pfam02080
1132507006125	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1132507006126	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
1132507006127	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507006128	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1132507006129	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507006130	putative substrate translocation pore; other site
1132507006131	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1132507006132	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1132507006133	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507006134	active site
1132507006135	motif I; other site
1132507006136	motif II; other site
1132507006137	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507006138	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1132507006139	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507006140	putative substrate translocation pore; other site
1132507006141	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1132507006142	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1132507006143	active site
1132507006144	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1132507006145	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1132507006146	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507006147	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1132507006148	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1132507006149	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1132507006150	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1132507006151	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1132507006152	putative C-terminal domain interface [polypeptide binding]; other site
1132507006153	putative GSH binding site (G-site) [chemical binding]; other site
1132507006154	putative dimer interface [polypeptide binding]; other site
1132507006155	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1132507006156	putative N-terminal domain interface [polypeptide binding]; other site
1132507006157	putative dimer interface [polypeptide binding]; other site
1132507006158	putative substrate binding pocket (H-site) [chemical binding]; other site
1132507006159	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1132507006160	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1132507006161	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1132507006162	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1132507006163	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1132507006164	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507006165	FeS/SAM binding site; other site
1132507006166	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1132507006167	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1132507006168	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507006169	dimer interface [polypeptide binding]; other site
1132507006170	conserved gate region; other site
1132507006171	putative PBP binding loops; other site
1132507006172	ABC-ATPase subunit interface; other site
1132507006173	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1132507006174	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507006175	dimer interface [polypeptide binding]; other site
1132507006176	conserved gate region; other site
1132507006177	putative PBP binding loops; other site
1132507006178	ABC-ATPase subunit interface; other site
1132507006179	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1132507006180	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1132507006181	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1132507006182	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507006183	Walker A/P-loop; other site
1132507006184	ATP binding site [chemical binding]; other site
1132507006185	Q-loop/lid; other site
1132507006186	ABC transporter signature motif; other site
1132507006187	Walker B; other site
1132507006188	D-loop; other site
1132507006189	H-loop/switch region; other site
1132507006190	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1132507006191	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507006192	Walker A/P-loop; other site
1132507006193	ATP binding site [chemical binding]; other site
1132507006194	Q-loop/lid; other site
1132507006195	ABC transporter signature motif; other site
1132507006196	Walker B; other site
1132507006197	D-loop; other site
1132507006198	H-loop/switch region; other site
1132507006199	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1132507006200	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1132507006201	catalytic nucleophile [active]
1132507006202	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1132507006203	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1132507006204	dimer interface [polypeptide binding]; other site
1132507006205	putative functional site; other site
1132507006206	putative MPT binding site; other site
1132507006207	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1132507006208	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1132507006209	ATP binding site [chemical binding]; other site
1132507006210	substrate interface [chemical binding]; other site
1132507006211	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1132507006212	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507006213	FeS/SAM binding site; other site
1132507006214	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1132507006215	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1132507006216	dimer interface [polypeptide binding]; other site
1132507006217	active site
1132507006218	glycine loop; other site
1132507006219	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1132507006220	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507006221	active site
1132507006222	motif I; other site
1132507006223	motif II; other site
1132507006224	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507006225	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1132507006226	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1132507006227	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1132507006228	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507006229	Walker A/P-loop; other site
1132507006230	ATP binding site [chemical binding]; other site
1132507006231	ABC transporter signature motif; other site
1132507006232	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1132507006233	Walker B; other site
1132507006234	ABC transporter; Region: ABC_tran_2; pfam12848
1132507006235	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1132507006236	L,D-transpeptidase; Provisional; Region: PRK10260
1132507006237	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1132507006238	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1132507006239	transmembrane helices; other site
1132507006240	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1132507006241	manganese transport regulator MntR; Provisional; Region: PRK11050
1132507006242	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1132507006243	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1132507006244	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1132507006245	Sulfatase; Region: Sulfatase; pfam00884
1132507006246	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507006247	outer membrane protein X; Provisional; Region: ompX; PRK09408
1132507006248	threonine and homoserine efflux system; Provisional; Region: PRK10532
1132507006249	EamA-like transporter family; Region: EamA; pfam00892
1132507006250	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1132507006251	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1132507006252	dimerization interface [polypeptide binding]; other site
1132507006253	DPS ferroxidase diiron center [ion binding]; other site
1132507006254	ion pore; other site
1132507006255	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1132507006256	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507006257	substrate binding pocket [chemical binding]; other site
1132507006258	membrane-bound complex binding site; other site
1132507006259	hinge residues; other site
1132507006260	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1132507006261	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507006262	dimer interface [polypeptide binding]; other site
1132507006263	conserved gate region; other site
1132507006264	putative PBP binding loops; other site
1132507006265	ABC-ATPase subunit interface; other site
1132507006266	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1132507006267	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1132507006268	Walker A/P-loop; other site
1132507006269	ATP binding site [chemical binding]; other site
1132507006270	Q-loop/lid; other site
1132507006271	ABC transporter signature motif; other site
1132507006272	Walker B; other site
1132507006273	D-loop; other site
1132507006274	H-loop/switch region; other site
1132507006275	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1132507006276	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1132507006277	hypothetical protein; Provisional; Region: PRK11019
1132507006278	hypothetical protein; Provisional; Region: PRK10259
1132507006279	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1132507006280	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1132507006281	ATP binding site [chemical binding]; other site
1132507006282	Mg++ binding site [ion binding]; other site
1132507006283	motif III; other site
1132507006284	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507006285	nucleotide binding region [chemical binding]; other site
1132507006286	ATP-binding site [chemical binding]; other site
1132507006287	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1132507006288	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507006289	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1132507006290	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1132507006291	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1132507006292	HlyD family secretion protein; Region: HlyD_3; pfam13437
1132507006293	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1132507006294	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1132507006295	Walker A/P-loop; other site
1132507006296	ATP binding site [chemical binding]; other site
1132507006297	Q-loop/lid; other site
1132507006298	ABC transporter signature motif; other site
1132507006299	Walker B; other site
1132507006300	D-loop; other site
1132507006301	H-loop/switch region; other site
1132507006302	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1132507006303	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1132507006304	Walker A/P-loop; other site
1132507006305	ATP binding site [chemical binding]; other site
1132507006306	Q-loop/lid; other site
1132507006307	ABC transporter signature motif; other site
1132507006308	Walker B; other site
1132507006309	D-loop; other site
1132507006310	H-loop/switch region; other site
1132507006311	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1132507006312	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1132507006313	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1132507006314	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1132507006315	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1132507006316	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1132507006317	putative catalytic site [active]
1132507006318	putative metal binding site [ion binding]; other site
1132507006319	putative phosphate binding site [ion binding]; other site
1132507006320	cardiolipin synthase 2; Provisional; Region: PRK11263
1132507006321	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1132507006322	putative active site [active]
1132507006323	catalytic site [active]
1132507006324	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1132507006325	putative active site [active]
1132507006326	catalytic site [active]
1132507006327	Predicted integral membrane protein [Function unknown]; Region: COG0392
1132507006328	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1132507006329	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1132507006330	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1132507006331	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1132507006332	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1132507006333	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1132507006334	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1132507006335	MoaE homodimer interface [polypeptide binding]; other site
1132507006336	MoaD interaction [polypeptide binding]; other site
1132507006337	active site residues [active]
1132507006338	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1132507006339	MoaE interaction surface [polypeptide binding]; other site
1132507006340	MoeB interaction surface [polypeptide binding]; other site
1132507006341	thiocarboxylated glycine; other site
1132507006342	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1132507006343	trimer interface [polypeptide binding]; other site
1132507006344	dimer interface [polypeptide binding]; other site
1132507006345	putative active site [active]
1132507006346	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1132507006347	MPT binding site; other site
1132507006348	trimer interface [polypeptide binding]; other site
1132507006349	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1132507006350	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507006351	FeS/SAM binding site; other site
1132507006352	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1132507006353	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1132507006354	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1132507006355	putative substrate binding pocket [chemical binding]; other site
1132507006356	dimer interface [polypeptide binding]; other site
1132507006357	phosphate binding site [ion binding]; other site
1132507006358	excinuclease ABC subunit B; Provisional; Region: PRK05298
1132507006359	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507006360	ATP binding site [chemical binding]; other site
1132507006361	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507006362	nucleotide binding region [chemical binding]; other site
1132507006363	ATP-binding site [chemical binding]; other site
1132507006364	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1132507006365	UvrB/uvrC motif; Region: UVR; pfam02151
1132507006366	AAA domain; Region: AAA_26; pfam13500
1132507006367	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1132507006368	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1132507006369	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507006370	S-adenosylmethionine binding site [chemical binding]; other site
1132507006371	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1132507006372	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1132507006373	substrate-cofactor binding pocket; other site
1132507006374	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507006375	catalytic residue [active]
1132507006376	biotin synthase; Provisional; Region: PRK15108
1132507006377	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507006378	FeS/SAM binding site; other site
1132507006379	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1132507006380	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1132507006381	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1132507006382	inhibitor-cofactor binding pocket; inhibition site
1132507006383	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507006384	catalytic residue [active]
1132507006385	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1132507006386	substrate binding site [chemical binding]; other site
1132507006387	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1132507006388	active sites [active]
1132507006389	tetramer interface [polypeptide binding]; other site
1132507006390	urocanate hydratase; Provisional; Region: PRK05414
1132507006391	histidine utilization repressor; Provisional; Region: PRK14999
1132507006392	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507006393	DNA-binding site [nucleotide binding]; DNA binding site
1132507006394	UTRA domain; Region: UTRA; pfam07702
1132507006395	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
1132507006396	putative active site [active]
1132507006397	putative metal binding site [ion binding]; other site
1132507006398	imidazolonepropionase; Validated; Region: PRK09356
1132507006399	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1132507006400	active site
1132507006401	acyl-CoA thioesterase; Provisional; Region: PRK10531
1132507006402	putative pectinesterase; Region: PLN02432; cl01911
1132507006403	6-phosphogluconolactonase; Provisional; Region: PRK11028
1132507006404	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1132507006405	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507006406	active site
1132507006407	motif I; other site
1132507006408	motif II; other site
1132507006409	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507006410	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1132507006411	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507006412	Walker A/P-loop; other site
1132507006413	ATP binding site [chemical binding]; other site
1132507006414	Q-loop/lid; other site
1132507006415	ABC transporter signature motif; other site
1132507006416	Walker B; other site
1132507006417	D-loop; other site
1132507006418	H-loop/switch region; other site
1132507006419	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1132507006420	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1132507006421	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507006422	dimer interface [polypeptide binding]; other site
1132507006423	conserved gate region; other site
1132507006424	putative PBP binding loops; other site
1132507006425	ABC-ATPase subunit interface; other site
1132507006426	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1132507006427	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507006428	substrate binding pocket [chemical binding]; other site
1132507006429	membrane-bound complex binding site; other site
1132507006430	hinge residues; other site
1132507006431	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1132507006432	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1132507006433	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1132507006434	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1132507006435	TOBE domain; Region: TOBE; pfam03459
1132507006436	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1132507006437	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507006438	Walker A/P-loop; other site
1132507006439	ATP binding site [chemical binding]; other site
1132507006440	Q-loop/lid; other site
1132507006441	ABC transporter signature motif; other site
1132507006442	Walker B; other site
1132507006443	D-loop; other site
1132507006444	H-loop/switch region; other site
1132507006445	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507006446	Walker A/P-loop; other site
1132507006447	ATP binding site [chemical binding]; other site
1132507006448	Q-loop/lid; other site
1132507006449	ABC transporter signature motif; other site
1132507006450	Walker B; other site
1132507006451	D-loop; other site
1132507006452	H-loop/switch region; other site
1132507006453	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
1132507006454	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1132507006455	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1132507006456	NAD binding site [chemical binding]; other site
1132507006457	homodimer interface [polypeptide binding]; other site
1132507006458	active site
1132507006459	substrate binding site [chemical binding]; other site
1132507006460	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1132507006461	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1132507006462	dimer interface [polypeptide binding]; other site
1132507006463	active site
1132507006464	galactokinase; Provisional; Region: PRK05101
1132507006465	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1132507006466	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1132507006467	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1132507006468	active site
1132507006469	catalytic residues [active]
1132507006470	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1132507006471	catalytic core [active]
1132507006472	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1132507006473	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1132507006474	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1132507006475	Walker A/P-loop; other site
1132507006476	ATP binding site [chemical binding]; other site
1132507006477	Q-loop/lid; other site
1132507006478	ABC transporter signature motif; other site
1132507006479	Walker B; other site
1132507006480	D-loop; other site
1132507006481	H-loop/switch region; other site
1132507006482	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1132507006483	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1132507006484	dimer interface [polypeptide binding]; other site
1132507006485	putative PBP binding regions; other site
1132507006486	ABC-ATPase subunit  interface; other site
1132507006487	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1132507006488	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1132507006489	YbgS-like protein; Region: YbgS; pfam13985
1132507006490	zinc transporter ZitB; Provisional; Region: PRK03557
1132507006491	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1132507006492	quinolinate synthetase; Provisional; Region: PRK09375
1132507006493	tol-pal system protein YbgF; Provisional; Region: PRK10803
1132507006494	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1132507006495	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1132507006496	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1132507006497	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1132507006498	ligand binding site [chemical binding]; other site
1132507006499	translocation protein TolB; Provisional; Region: tolB; PRK03629
1132507006500	TolB amino-terminal domain; Region: TolB_N; pfam04052
1132507006501	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1132507006502	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1132507006503	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1132507006504	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1132507006505	TolA C-terminal; Region: TolA; pfam06519
1132507006506	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1132507006507	colicin uptake protein TolR; Provisional; Region: PRK11024
1132507006508	colicin uptake protein TolQ; Provisional; Region: PRK10801
1132507006509	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1132507006510	active site
1132507006511	hypothetical protein; Provisional; Region: PRK10588
1132507006512	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
1132507006513	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1132507006514	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1132507006515	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1132507006516	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1132507006517	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1132507006518	CoA binding domain; Region: CoA_binding; smart00881
1132507006519	CoA-ligase; Region: Ligase_CoA; pfam00549
1132507006520	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1132507006521	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1132507006522	CoA-ligase; Region: Ligase_CoA; pfam00549
1132507006523	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1132507006524	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1132507006525	E3 interaction surface; other site
1132507006526	lipoyl attachment site [posttranslational modification]; other site
1132507006527	e3 binding domain; Region: E3_binding; pfam02817
1132507006528	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1132507006529	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1132507006530	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1132507006531	TPP-binding site [chemical binding]; other site
1132507006532	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1132507006533	dimer interface [polypeptide binding]; other site
1132507006534	PYR/PP interface [polypeptide binding]; other site
1132507006535	TPP binding site [chemical binding]; other site
1132507006536	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1132507006537	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1132507006538	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1132507006539	L-aspartate oxidase; Provisional; Region: PRK06175
1132507006540	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1132507006541	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1132507006542	SdhC subunit interface [polypeptide binding]; other site
1132507006543	proximal heme binding site [chemical binding]; other site
1132507006544	cardiolipin binding site; other site
1132507006545	Iron-sulfur protein interface; other site
1132507006546	proximal quinone binding site [chemical binding]; other site
1132507006547	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1132507006548	Iron-sulfur protein interface; other site
1132507006549	proximal quinone binding site [chemical binding]; other site
1132507006550	SdhD (CybS) interface [polypeptide binding]; other site
1132507006551	proximal heme binding site [chemical binding]; other site
1132507006552	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1132507006553	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1132507006554	dimer interface [polypeptide binding]; other site
1132507006555	active site
1132507006556	citrylCoA binding site [chemical binding]; other site
1132507006557	NADH binding [chemical binding]; other site
1132507006558	cationic pore residues; other site
1132507006559	oxalacetate/citrate binding site [chemical binding]; other site
1132507006560	coenzyme A binding site [chemical binding]; other site
1132507006561	catalytic triad [active]
1132507006562	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1132507006563	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1132507006564	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1132507006565	endonuclease VIII; Provisional; Region: PRK10445
1132507006566	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
1132507006567	DNA binding site [nucleotide binding]
1132507006568	catalytic residue [active]
1132507006569	putative catalytic residues [active]
1132507006570	H2TH interface [polypeptide binding]; other site
1132507006571	intercalation triad [nucleotide binding]; other site
1132507006572	substrate specificity determining residue; other site
1132507006573	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1132507006574	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1132507006575	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
1132507006576	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1132507006577	active site
1132507006578	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1132507006579	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1132507006580	active site
1132507006581	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1132507006582	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1132507006583	Walker A/P-loop; other site
1132507006584	ATP binding site [chemical binding]; other site
1132507006585	Q-loop/lid; other site
1132507006586	ABC transporter signature motif; other site
1132507006587	Walker B; other site
1132507006588	D-loop; other site
1132507006589	H-loop/switch region; other site
1132507006590	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1132507006591	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1132507006592	putative ADP-binding pocket [chemical binding]; other site
1132507006593	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1132507006594	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1132507006595	active site
1132507006596	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
1132507006597	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1132507006598	UDP-galactopyranose mutase; Region: GLF; pfam03275
1132507006599	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1132507006600	active site
1132507006601	DNA binding site [nucleotide binding]
1132507006602	Int/Topo IB signature motif; other site
1132507006603	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
1132507006604	putative active site [active]
1132507006605	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1132507006606	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1132507006607	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1132507006608	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1132507006609	metal-binding protein; Provisional; Region: PRK10799
1132507006610	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1132507006611	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507006612	putative substrate translocation pore; other site
1132507006613	POT family; Region: PTR2; pfam00854
1132507006614	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1132507006615	DNA photolyase; Region: DNA_photolyase; pfam00875
1132507006616	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1132507006617	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1132507006618	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1132507006619	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1132507006620	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1132507006621	sensor protein KdpD; Provisional; Region: PRK10490
1132507006622	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1132507006623	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1132507006624	Ligand Binding Site [chemical binding]; other site
1132507006625	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1132507006626	GAF domain; Region: GAF_3; pfam13492
1132507006627	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507006628	dimer interface [polypeptide binding]; other site
1132507006629	phosphorylation site [posttranslational modification]
1132507006630	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507006631	ATP binding site [chemical binding]; other site
1132507006632	Mg2+ binding site [ion binding]; other site
1132507006633	G-X-G motif; other site
1132507006634	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1132507006635	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507006636	active site
1132507006637	phosphorylation site [posttranslational modification]
1132507006638	intermolecular recognition site; other site
1132507006639	dimerization interface [polypeptide binding]; other site
1132507006640	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507006641	DNA binding site [nucleotide binding]
1132507006642	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1132507006643	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1132507006644	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1132507006645	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1132507006646	catalytic residue [active]
1132507006647	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1132507006648	putrescine transporter; Provisional; Region: potE; PRK10655
1132507006649	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
1132507006650	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
1132507006651	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1132507006652	active site
1132507006653	substrate binding site [chemical binding]; other site
1132507006654	metal binding site [ion binding]; metal-binding site
1132507006655	replication initiation regulator SeqA; Provisional; Region: PRK11187
1132507006656	acyl-CoA esterase; Provisional; Region: PRK10673
1132507006657	PGAP1-like protein; Region: PGAP1; pfam07819
1132507006658	LexA regulated protein; Provisional; Region: PRK11675
1132507006659	flavodoxin FldA; Validated; Region: PRK09267
1132507006660	ferric uptake regulator; Provisional; Region: fur; PRK09462
1132507006661	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1132507006662	metal binding site 2 [ion binding]; metal-binding site
1132507006663	putative DNA binding helix; other site
1132507006664	metal binding site 1 [ion binding]; metal-binding site
1132507006665	dimer interface [polypeptide binding]; other site
1132507006666	structural Zn2+ binding site [ion binding]; other site
1132507006667	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507006668	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507006669	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1132507006670	putative dimerization interface [polypeptide binding]; other site
1132507006671	tricarballylate dehydrogenase; Validated; Region: PRK08274
1132507006672	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1132507006673	tricarballylate utilization protein B; Provisional; Region: PRK15033
1132507006674	citrate-proton symporter; Provisional; Region: PRK15075
1132507006675	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507006676	putative substrate translocation pore; other site
1132507006677	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1132507006678	YbfN-like lipoprotein; Region: YbfN; pfam13982
1132507006679	outer membrane porin, OprD family; Region: OprD; pfam03573
1132507006680	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1132507006681	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1132507006682	active site
1132507006683	HIGH motif; other site
1132507006684	nucleotide binding site [chemical binding]; other site
1132507006685	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1132507006686	KMSKS motif; other site
1132507006687	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1132507006688	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1132507006689	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1132507006690	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1132507006691	active site turn [active]
1132507006692	phosphorylation site [posttranslational modification]
1132507006693	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1132507006694	HPr interaction site; other site
1132507006695	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1132507006696	active site
1132507006697	phosphorylation site [posttranslational modification]
1132507006698	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1132507006699	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1132507006700	active site
1132507006701	trimer interface [polypeptide binding]; other site
1132507006702	allosteric site; other site
1132507006703	active site lid [active]
1132507006704	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1132507006705	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1132507006706	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1132507006707	active site
1132507006708	dimer interface [polypeptide binding]; other site
1132507006709	MarR family; Region: MarR; pfam01047
1132507006710	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1132507006711	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1132507006712	nucleotide binding site [chemical binding]; other site
1132507006713	UMP phosphatase; Provisional; Region: PRK10444
1132507006714	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507006715	active site
1132507006716	motif I; other site
1132507006717	motif II; other site
1132507006718	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507006719	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1132507006720	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1132507006721	active site
1132507006722	dimer interface [polypeptide binding]; other site
1132507006723	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1132507006724	Ligand Binding Site [chemical binding]; other site
1132507006725	Molecular Tunnel; other site
1132507006726	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1132507006727	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1132507006728	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1132507006729	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1132507006730	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507006731	FeS/SAM binding site; other site
1132507006732	TRAM domain; Region: TRAM; pfam01938
1132507006733	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1132507006734	PhoH-like protein; Region: PhoH; pfam02562
1132507006735	metal-binding heat shock protein; Provisional; Region: PRK00016
1132507006736	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1132507006737	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1132507006738	Transporter associated domain; Region: CorC_HlyC; smart01091
1132507006739	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1132507006740	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1132507006741	putative active site [active]
1132507006742	catalytic triad [active]
1132507006743	putative dimer interface [polypeptide binding]; other site
1132507006744	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1132507006745	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507006746	substrate binding pocket [chemical binding]; other site
1132507006747	membrane-bound complex binding site; other site
1132507006748	hinge residues; other site
1132507006749	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1132507006750	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507006751	dimer interface [polypeptide binding]; other site
1132507006752	conserved gate region; other site
1132507006753	putative PBP binding loops; other site
1132507006754	ABC-ATPase subunit interface; other site
1132507006755	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1132507006756	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507006757	dimer interface [polypeptide binding]; other site
1132507006758	conserved gate region; other site
1132507006759	putative PBP binding loops; other site
1132507006760	ABC-ATPase subunit interface; other site
1132507006761	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1132507006762	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1132507006763	Walker A/P-loop; other site
1132507006764	ATP binding site [chemical binding]; other site
1132507006765	Q-loop/lid; other site
1132507006766	ABC transporter signature motif; other site
1132507006767	Walker B; other site
1132507006768	D-loop; other site
1132507006769	H-loop/switch region; other site
1132507006770	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1132507006771	active site
1132507006772	tetramer interface [polypeptide binding]; other site
1132507006773	hypothetical protein; Provisional; Region: PRK11032
1132507006774	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1132507006775	Propionate catabolism activator; Region: PrpR_N; pfam06506
1132507006776	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1132507006777	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507006778	Walker A motif; other site
1132507006779	ATP binding site [chemical binding]; other site
1132507006780	Walker B motif; other site
1132507006781	arginine finger; other site
1132507006782	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
1132507006783	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1132507006784	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1132507006785	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1132507006786	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1132507006787	HIGH motif; other site
1132507006788	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1132507006789	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1132507006790	active site
1132507006791	KMSKS motif; other site
1132507006792	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1132507006793	tRNA binding surface [nucleotide binding]; other site
1132507006794	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1132507006795	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1132507006796	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1132507006797	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1132507006798	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1132507006799	active site
1132507006800	(T/H)XGH motif; other site
1132507006801	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
1132507006802	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507006803	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507006804	homodimer interface [polypeptide binding]; other site
1132507006805	catalytic residue [active]
1132507006806	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1132507006807	catalytic core [active]
1132507006808	ribosome-associated protein; Provisional; Region: PRK11538
1132507006809	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1132507006810	penicillin-binding protein 2; Provisional; Region: PRK10795
1132507006811	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1132507006812	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1132507006813	cell wall shape-determining protein; Provisional; Region: PRK10794
1132507006814	rare lipoprotein A; Provisional; Region: PRK10672
1132507006815	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1132507006816	Sporulation related domain; Region: SPOR; pfam05036
1132507006817	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1132507006818	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1132507006819	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1132507006820	hypothetical protein; Provisional; Region: PRK04998
1132507006821	lipoate-protein ligase B; Provisional; Region: PRK14342
1132507006822	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1132507006823	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507006824	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1132507006825	substrate binding pocket [chemical binding]; other site
1132507006826	dimerization interface [polypeptide binding]; other site
1132507006827	lipoyl synthase; Provisional; Region: PRK05481
1132507006828	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507006829	FeS/SAM binding site; other site
1132507006830	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1132507006831	chromosome condensation membrane protein; Provisional; Region: PRK14196
1132507006832	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1132507006833	DNA-binding site [nucleotide binding]; DNA binding site
1132507006834	RNA-binding motif; other site
1132507006835	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1132507006836	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1132507006837	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1132507006838	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
1132507006839	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507006840	active site
1132507006841	phosphorylation site [posttranslational modification]
1132507006842	intermolecular recognition site; other site
1132507006843	dimerization interface [polypeptide binding]; other site
1132507006844	Transcriptional regulator; Region: CitT; pfam12431
1132507006845	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
1132507006846	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1132507006847	putative active site [active]
1132507006848	heme pocket [chemical binding]; other site
1132507006849	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507006850	ATP binding site [chemical binding]; other site
1132507006851	Mg2+ binding site [ion binding]; other site
1132507006852	G-X-G motif; other site
1132507006853	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1132507006854	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1132507006855	putative active site [active]
1132507006856	(T/H)XGH motif; other site
1132507006857	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1132507006858	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1132507006859	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1132507006860	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1132507006861	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; cl01498
1132507006862	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
1132507006863	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1132507006864	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1132507006865	transmembrane helices; other site
1132507006866	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1132507006867	B1 nucleotide binding pocket [chemical binding]; other site
1132507006868	B2 nucleotide binding pocket [chemical binding]; other site
1132507006869	CAS motifs; other site
1132507006870	active site
1132507006871	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1132507006872	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1132507006873	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1132507006874	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1132507006875	NAD binding site [chemical binding]; other site
1132507006876	catalytic Zn binding site [ion binding]; other site
1132507006877	structural Zn binding site [ion binding]; other site
1132507006878	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1132507006879	Ligand Binding Site [chemical binding]; other site
1132507006880	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1132507006881	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1132507006882	4Fe-4S binding domain; Region: Fer4; cl02805
1132507006883	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1132507006884	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
1132507006885	putative [4Fe-4S] binding site [ion binding]; other site
1132507006886	putative molybdopterin cofactor binding site [chemical binding]; other site
1132507006887	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
1132507006888	molybdopterin cofactor binding site; other site
1132507006889	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1132507006890	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507006891	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1132507006892	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1132507006893	catalytic residue [active]
1132507006894	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1132507006895	catalytic residues [active]
1132507006896	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1132507006897	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507006898	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1132507006899	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1132507006900	dimer interface [polypeptide binding]; other site
1132507006901	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1132507006902	catalytic triad [active]
1132507006903	peroxidatic and resolving cysteines [active]
1132507006904	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1132507006905	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1132507006906	dimerization domain [polypeptide binding]; other site
1132507006907	dimer interface [polypeptide binding]; other site
1132507006908	catalytic residues [active]
1132507006909	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1132507006910	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507006911	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507006912	dimerization interface [polypeptide binding]; other site
1132507006913	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1132507006914	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1132507006915	Active Sites [active]
1132507006916	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1132507006917	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1132507006918	ParB-like nuclease domain; Region: ParBc; pfam02195
1132507006919	methionine aminotransferase; Validated; Region: PRK09082
1132507006920	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507006921	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507006922	homodimer interface [polypeptide binding]; other site
1132507006923	catalytic residue [active]
1132507006924	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1132507006925	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1132507006926	putative active site [active]
1132507006927	metal binding site [ion binding]; metal-binding site
1132507006928	Uncharacterized small protein [Function unknown]; Region: COG2879
1132507006929	carbon starvation protein A; Provisional; Region: PRK15015
1132507006930	Carbon starvation protein CstA; Region: CstA; pfam02554
1132507006931	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1132507006932	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1132507006933	CoenzymeA binding site [chemical binding]; other site
1132507006934	subunit interaction site [polypeptide binding]; other site
1132507006935	PHB binding site; other site
1132507006936	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1132507006937	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1132507006938	putative NAD(P) binding site [chemical binding]; other site
1132507006939	active site
1132507006940	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1132507006941	hydrophobic substrate binding pocket; other site
1132507006942	Isochorismatase family; Region: Isochorismatase; pfam00857
1132507006943	active site
1132507006944	conserved cis-peptide bond; other site
1132507006945	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1132507006946	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
1132507006947	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1132507006948	acyl-activating enzyme (AAE) consensus motif; other site
1132507006949	active site
1132507006950	AMP binding site [chemical binding]; other site
1132507006951	substrate binding site [chemical binding]; other site
1132507006952	isochorismate synthase EntC; Provisional; Region: PRK15016
1132507006953	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1132507006954	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
1132507006955	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1132507006956	siderophore binding site; other site
1132507006957	enterobactin exporter EntS; Provisional; Region: PRK10489
1132507006958	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507006959	putative substrate translocation pore; other site
1132507006960	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1132507006961	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1132507006962	ABC-ATPase subunit  interface; other site
1132507006963	dimer interface [polypeptide binding]; other site
1132507006964	putative PBP binding regions; other site
1132507006965	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1132507006966	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1132507006967	ABC-ATPase subunit  interface; other site
1132507006968	dimer interface [polypeptide binding]; other site
1132507006969	putative PBP binding regions; other site
1132507006970	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1132507006971	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1132507006972	Walker A/P-loop; other site
1132507006973	ATP binding site [chemical binding]; other site
1132507006974	Q-loop/lid; other site
1132507006975	ABC transporter signature motif; other site
1132507006976	Walker B; other site
1132507006977	D-loop; other site
1132507006978	H-loop/switch region; other site
1132507006979	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1132507006980	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1132507006981	acyl-activating enzyme (AAE) consensus motif; other site
1132507006982	AMP binding site [chemical binding]; other site
1132507006983	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1132507006984	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
1132507006985	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1132507006986	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1132507006987	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1132507006988	outer membrane receptor FepA; Provisional; Region: PRK13524
1132507006989	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1132507006990	N-terminal plug; other site
1132507006991	ligand-binding site [chemical binding]; other site
1132507006992	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
1132507006993	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1132507006994	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
1132507006995	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
1132507006996	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1132507006997	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1132507006998	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507006999	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1132507007000	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507007001	hypothetical protein; Provisional; Region: PRK10250
1132507007002	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1132507007003	dimer interface [polypeptide binding]; other site
1132507007004	FMN binding site [chemical binding]; other site
1132507007005	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1132507007006	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1132507007007	active site
1132507007008	catalytic triad [active]
1132507007009	oxyanion hole [active]
1132507007010	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1132507007011	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1132507007012	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1132507007013	phenylalanine transporter; Provisional; Region: PRK10249
1132507007014	Spore germination protein; Region: Spore_permease; cl17796
1132507007015	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
1132507007016	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
1132507007017	HSP70 interaction site [polypeptide binding]; other site
1132507007018	Predicted membrane protein [Function unknown]; Region: COG3059
1132507007019	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1132507007020	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
1132507007021	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507007022	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1132507007023	Cupin; Region: Cupin_6; pfam12852
1132507007024	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1132507007025	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507007026	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
1132507007027	Predicted membrane protein [Function unknown]; Region: COG2246
1132507007028	GtrA-like protein; Region: GtrA; pfam04138
1132507007029	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1132507007030	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1132507007031	Ligand binding site; other site
1132507007032	Putative Catalytic site; other site
1132507007033	DXD motif; other site
1132507007034	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1132507007035	Transposase; Region: HTH_Tnp_1; pfam01527
1132507007036	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
1132507007037	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507007038	DNA binding residues [nucleotide binding]
1132507007039	dimerization interface [polypeptide binding]; other site
1132507007040	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1132507007041	transcriptional regulator FimZ; Provisional; Region: PRK09935
1132507007042	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507007043	active site
1132507007044	phosphorylation site [posttranslational modification]
1132507007045	intermolecular recognition site; other site
1132507007046	dimerization interface [polypeptide binding]; other site
1132507007047	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507007048	DNA binding residues [nucleotide binding]
1132507007049	dimerization interface [polypeptide binding]; other site
1132507007050	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
1132507007051	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
1132507007052	outer membrane usher protein FimD; Provisional; Region: PRK15198
1132507007053	PapC N-terminal domain; Region: PapC_N; pfam13954
1132507007054	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1132507007055	PapC C-terminal domain; Region: PapC_C; pfam13953
1132507007056	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1132507007057	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507007058	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507007059	fimbrial protein FimI; Provisional; Region: PRK15200
1132507007060	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
1132507007061	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1132507007062	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1132507007063	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1132507007064	homodimer interface [polypeptide binding]; other site
1132507007065	NADP binding site [chemical binding]; other site
1132507007066	substrate binding site [chemical binding]; other site
1132507007067	ribosome-associated protein; Provisional; Region: PRK11507
1132507007068	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1132507007069	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1132507007070	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1132507007071	active site
1132507007072	HIGH motif; other site
1132507007073	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1132507007074	KMSKS motif; other site
1132507007075	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1132507007076	tRNA binding surface [nucleotide binding]; other site
1132507007077	anticodon binding site; other site
1132507007078	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1132507007079	substrate binding site [chemical binding]; other site
1132507007080	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1132507007081	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1132507007082	putative active site [active]
1132507007083	putative metal binding site [ion binding]; other site
1132507007084	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1132507007085	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1132507007086	ATP-grasp domain; Region: ATP-grasp; pfam02222
1132507007087	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1132507007088	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1132507007089	putative substrate binding site [chemical binding]; other site
1132507007090	nucleotide binding site [chemical binding]; other site
1132507007091	nucleotide binding site [chemical binding]; other site
1132507007092	homodimer interface [polypeptide binding]; other site
1132507007093	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1132507007094	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1132507007095	membrane protein FdrA; Validated; Region: PRK06091
1132507007096	CoA binding domain; Region: CoA_binding; pfam02629
1132507007097	CoA-ligase; Region: Ligase_CoA; pfam00549
1132507007098	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
1132507007099	allantoate amidohydrolase; Region: AllC; TIGR03176
1132507007100	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1132507007101	active site
1132507007102	metal binding site [ion binding]; metal-binding site
1132507007103	dimer interface [polypeptide binding]; other site
1132507007104	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
1132507007105	Mif2/CENP-C like; Region: Mif2; pfam11699
1132507007106	Cupin domain; Region: Cupin_2; pfam07883
1132507007107	glycerate kinase II; Provisional; Region: PRK09932
1132507007108	putative uracil/xanthine transporter; Provisional; Region: PRK11412
1132507007109	allantoinase; Provisional; Region: PRK08044
1132507007110	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
1132507007111	active site
1132507007112	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507007113	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1132507007114	putative substrate translocation pore; other site
1132507007115	tartronate semialdehyde reductase; Provisional; Region: PRK15059
1132507007116	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1132507007117	hydroxypyruvate isomerase; Provisional; Region: PRK09997
1132507007118	glyoxylate carboligase; Provisional; Region: PRK11269
1132507007119	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1132507007120	PYR/PP interface [polypeptide binding]; other site
1132507007121	dimer interface [polypeptide binding]; other site
1132507007122	TPP binding site [chemical binding]; other site
1132507007123	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1132507007124	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
1132507007125	TPP-binding site [chemical binding]; other site
1132507007126	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
1132507007127	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1132507007128	Bacterial transcriptional regulator; Region: IclR; pfam01614
1132507007129	Ureidoglycolate hydrolase; Region: Ureidogly_hydro; cl01250
1132507007130	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1132507007131	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507007132	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507007133	dimerization interface [polypeptide binding]; other site
1132507007134	Predicted ATPase [General function prediction only]; Region: COG2603
1132507007135	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1132507007136	active site residue [active]
1132507007137	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507007138	dimer interface [polypeptide binding]; other site
1132507007139	conserved gate region; other site
1132507007140	ABC-ATPase subunit interface; other site
1132507007141	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
1132507007142	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1132507007143	Walker A/P-loop; other site
1132507007144	ATP binding site [chemical binding]; other site
1132507007145	Q-loop/lid; other site
1132507007146	ABC transporter signature motif; other site
1132507007147	Walker B; other site
1132507007148	D-loop; other site
1132507007149	H-loop/switch region; other site
1132507007150	NIL domain; Region: NIL; pfam09383
1132507007151	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1132507007152	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1132507007153	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1132507007154	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1132507007155	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1132507007156	FtsX-like permease family; Region: FtsX; pfam02687
1132507007157	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1132507007158	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1132507007159	Walker A/P-loop; other site
1132507007160	ATP binding site [chemical binding]; other site
1132507007161	Q-loop/lid; other site
1132507007162	ABC transporter signature motif; other site
1132507007163	Walker B; other site
1132507007164	D-loop; other site
1132507007165	H-loop/switch region; other site
1132507007166	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1132507007167	active site
1132507007168	catalytic triad [active]
1132507007169	oxyanion hole [active]
1132507007170	switch loop; other site
1132507007171	oxidoreductase; Provisional; Region: PRK08017
1132507007172	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1132507007173	NADP binding site [chemical binding]; other site
1132507007174	active site
1132507007175	steroid binding site; other site
1132507007176	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1132507007177	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1132507007178	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1132507007179	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1132507007180	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1132507007181	Walker A/P-loop; other site
1132507007182	ATP binding site [chemical binding]; other site
1132507007183	Q-loop/lid; other site
1132507007184	ABC transporter signature motif; other site
1132507007185	Walker B; other site
1132507007186	D-loop; other site
1132507007187	H-loop/switch region; other site
1132507007188	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1132507007189	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1132507007190	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1132507007191	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1132507007192	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1132507007193	DNA binding residues [nucleotide binding]
1132507007194	dimer interface [polypeptide binding]; other site
1132507007195	copper binding site [ion binding]; other site
1132507007196	copper exporting ATPase; Provisional; Region: copA; PRK10671
1132507007197	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1132507007198	metal-binding site [ion binding]
1132507007199	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1132507007200	metal-binding site [ion binding]
1132507007201	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1132507007202	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507007203	motif II; other site
1132507007204	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1132507007205	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
1132507007206	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1132507007207	putative deacylase active site [active]
1132507007208	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507007209	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1132507007210	putative substrate translocation pore; other site
1132507007211	putative cation:proton antiport protein; Provisional; Region: PRK10669
1132507007212	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1132507007213	TrkA-N domain; Region: TrkA_N; pfam02254
1132507007214	inosine/guanosine kinase; Provisional; Region: PRK15074
1132507007215	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1132507007216	acetyl esterase; Provisional; Region: PRK10162
1132507007217	ferrochelatase; Reviewed; Region: hemH; PRK00035
1132507007218	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1132507007219	C-terminal domain interface [polypeptide binding]; other site
1132507007220	active site
1132507007221	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1132507007222	active site
1132507007223	N-terminal domain interface [polypeptide binding]; other site
1132507007224	adenylate kinase; Reviewed; Region: adk; PRK00279
1132507007225	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1132507007226	AMP-binding site [chemical binding]; other site
1132507007227	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1132507007228	heat shock protein 90; Provisional; Region: PRK05218
1132507007229	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507007230	ATP binding site [chemical binding]; other site
1132507007231	Mg2+ binding site [ion binding]; other site
1132507007232	G-X-G motif; other site
1132507007233	recombination protein RecR; Reviewed; Region: recR; PRK00076
1132507007234	RecR protein; Region: RecR; pfam02132
1132507007235	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1132507007236	putative active site [active]
1132507007237	putative metal-binding site [ion binding]; other site
1132507007238	tetramer interface [polypeptide binding]; other site
1132507007239	hypothetical protein; Validated; Region: PRK00153
1132507007240	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1132507007241	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507007242	Walker A motif; other site
1132507007243	ATP binding site [chemical binding]; other site
1132507007244	Walker B motif; other site
1132507007245	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1132507007246	arginine finger; other site
1132507007247	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1132507007248	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1132507007249	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1132507007250	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1132507007251	active site
1132507007252	hypothetical protein; Provisional; Region: PRK10527
1132507007253	Primosomal replication protein priB and priC; Region: priB_priC; cl11483
1132507007254	hypothetical protein; Provisional; Region: PRK11038
1132507007255	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1132507007256	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1132507007257	hypothetical protein; Provisional; Region: PRK11281
1132507007258	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1132507007259	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
1132507007260	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1132507007261	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1132507007262	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507007263	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1132507007264	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1132507007265	HlyD family secretion protein; Region: HlyD_3; pfam13437
1132507007266	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1132507007267	Protein export membrane protein; Region: SecD_SecF; cl14618
1132507007268	Protein export membrane protein; Region: SecD_SecF; cl14618
1132507007269	Hha toxicity attenuator; Provisional; Region: PRK10667
1132507007270	gene expression modulator; Provisional; Region: PRK10945
1132507007271	maltose O-acetyltransferase; Provisional; Region: PRK10092
1132507007272	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1132507007273	active site
1132507007274	substrate binding site [chemical binding]; other site
1132507007275	trimer interface [polypeptide binding]; other site
1132507007276	CoA binding site [chemical binding]; other site
1132507007277	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1132507007278	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1132507007279	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1132507007280	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1132507007281	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507007282	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1132507007283	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1132507007284	DNA binding site [nucleotide binding]
1132507007285	active site
1132507007286	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1132507007287	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1132507007288	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1132507007289	active site
1132507007290	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1132507007291	catalytic triad [active]
1132507007292	dimer interface [polypeptide binding]; other site
1132507007293	ammonium transporter; Provisional; Region: PRK10666
1132507007294	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1132507007295	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1132507007296	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1132507007297	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1132507007298	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507007299	Walker A/P-loop; other site
1132507007300	ATP binding site [chemical binding]; other site
1132507007301	Q-loop/lid; other site
1132507007302	ABC transporter signature motif; other site
1132507007303	Walker B; other site
1132507007304	D-loop; other site
1132507007305	H-loop/switch region; other site
1132507007306	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1132507007307	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1132507007308	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507007309	Walker A/P-loop; other site
1132507007310	ATP binding site [chemical binding]; other site
1132507007311	Q-loop/lid; other site
1132507007312	ABC transporter signature motif; other site
1132507007313	Walker B; other site
1132507007314	D-loop; other site
1132507007315	H-loop/switch region; other site
1132507007316	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1132507007317	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1132507007318	putative DNA binding site [nucleotide binding]; other site
1132507007319	putative Zn2+ binding site [ion binding]; other site
1132507007320	AsnC family; Region: AsnC_trans_reg; pfam01037
1132507007321	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1132507007322	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1132507007323	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1132507007324	catalytic residue [active]
1132507007325	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507007326	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1132507007327	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507007328	active site
1132507007329	motif I; other site
1132507007330	motif II; other site
1132507007331	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1132507007332	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1132507007333	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1132507007334	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1132507007335	Ligand Binding Site [chemical binding]; other site
1132507007336	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1132507007337	active site
1132507007338	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1132507007339	periplasmic folding chaperone; Provisional; Region: PRK10788
1132507007340	SurA N-terminal domain; Region: SurA_N_3; cl07813
1132507007341	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1132507007342	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1132507007343	IHF dimer interface [polypeptide binding]; other site
1132507007344	IHF - DNA interface [nucleotide binding]; other site
1132507007345	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1132507007346	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1132507007347	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1132507007348	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507007349	Walker A motif; other site
1132507007350	ATP binding site [chemical binding]; other site
1132507007351	Walker B motif; other site
1132507007352	arginine finger; other site
1132507007353	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1132507007354	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1132507007355	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1132507007356	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507007357	Walker A motif; other site
1132507007358	ATP binding site [chemical binding]; other site
1132507007359	Walker B motif; other site
1132507007360	Iron permease FTR1 family; Region: FTR1; cl00475
1132507007361	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1132507007362	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1132507007363	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1132507007364	oligomer interface [polypeptide binding]; other site
1132507007365	active site residues [active]
1132507007366	trigger factor; Provisional; Region: tig; PRK01490
1132507007367	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1132507007368	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1132507007369	transcriptional regulator BolA; Provisional; Region: PRK11628
1132507007370	hypothetical protein; Provisional; Region: PRK11627
1132507007371	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1132507007372	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1132507007373	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507007374	putative substrate translocation pore; other site
1132507007375	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1132507007376	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1132507007377	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1132507007378	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1132507007379	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1132507007380	D-pathway; other site
1132507007381	Putative ubiquinol binding site [chemical binding]; other site
1132507007382	Low-spin heme (heme b) binding site [chemical binding]; other site
1132507007383	Putative water exit pathway; other site
1132507007384	Binuclear center (heme o3/CuB) [ion binding]; other site
1132507007385	K-pathway; other site
1132507007386	Putative proton exit pathway; other site
1132507007387	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1132507007388	Subunit I/III interface [polypeptide binding]; other site
1132507007389	Subunit III/IV interface [polypeptide binding]; other site
1132507007390	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1132507007391	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1132507007392	UbiA prenyltransferase family; Region: UbiA; pfam01040
1132507007393	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1132507007394	Sel1-like repeats; Region: SEL1; smart00671
1132507007395	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1132507007396	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1132507007397	Sel1-like repeats; Region: SEL1; smart00671
1132507007398	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507007399	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1132507007400	putative substrate translocation pore; other site
1132507007401	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1132507007402	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1132507007403	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1132507007404	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1132507007405	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1132507007406	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1132507007407	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1132507007408	conserved cys residue [active]
1132507007409	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
1132507007410	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507007411	motif II; other site
1132507007412	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1132507007413	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
1132507007414	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1132507007415	catalytic residue [active]
1132507007416	transcriptional regulator protein; Region: phnR; TIGR03337
1132507007417	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507007418	DNA-binding site [nucleotide binding]; DNA binding site
1132507007419	UTRA domain; Region: UTRA; pfam07702
1132507007420	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
1132507007421	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1132507007422	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
1132507007423	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507007424	Walker A/P-loop; other site
1132507007425	ATP binding site [chemical binding]; other site
1132507007426	Q-loop/lid; other site
1132507007427	ABC transporter signature motif; other site
1132507007428	Walker B; other site
1132507007429	D-loop; other site
1132507007430	H-loop/switch region; other site
1132507007431	TOBE domain; Region: TOBE_2; pfam08402
1132507007432	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
1132507007433	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507007434	dimer interface [polypeptide binding]; other site
1132507007435	conserved gate region; other site
1132507007436	putative PBP binding loops; other site
1132507007437	ABC-ATPase subunit interface; other site
1132507007438	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1132507007439	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507007440	dimer interface [polypeptide binding]; other site
1132507007441	conserved gate region; other site
1132507007442	putative PBP binding loops; other site
1132507007443	ABC-ATPase subunit interface; other site
1132507007444	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1132507007445	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1132507007446	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1132507007447	Ligand Binding Site [chemical binding]; other site
1132507007448	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1132507007449	active site residue [active]
1132507007450	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1132507007451	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1132507007452	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1132507007453	substrate binding pocket [chemical binding]; other site
1132507007454	chain length determination region; other site
1132507007455	substrate-Mg2+ binding site; other site
1132507007456	catalytic residues [active]
1132507007457	aspartate-rich region 1; other site
1132507007458	active site lid residues [active]
1132507007459	aspartate-rich region 2; other site
1132507007460	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1132507007461	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1132507007462	TPP-binding site; other site
1132507007463	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1132507007464	PYR/PP interface [polypeptide binding]; other site
1132507007465	dimer interface [polypeptide binding]; other site
1132507007466	TPP binding site [chemical binding]; other site
1132507007467	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1132507007468	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1132507007469	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1132507007470	active site
1132507007471	catalytic tetrad [active]
1132507007472	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1132507007473	tetramer interfaces [polypeptide binding]; other site
1132507007474	binuclear metal-binding site [ion binding]; other site
1132507007475	thiamine monophosphate kinase; Provisional; Region: PRK05731
1132507007476	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1132507007477	ATP binding site [chemical binding]; other site
1132507007478	dimerization interface [polypeptide binding]; other site
1132507007479	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1132507007480	putative RNA binding site [nucleotide binding]; other site
1132507007481	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1132507007482	homopentamer interface [polypeptide binding]; other site
1132507007483	active site
1132507007484	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1132507007485	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1132507007486	catalytic motif [active]
1132507007487	Zn binding site [ion binding]; other site
1132507007488	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1132507007489	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1132507007490	ATP cone domain; Region: ATP-cone; pfam03477
1132507007491	hypothetical protein; Provisional; Region: PRK11530
1132507007492	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1132507007493	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1132507007494	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1132507007495	active site
1132507007496	Predicted transcriptional regulator [Transcription]; Region: COG2378
1132507007497	HTH domain; Region: HTH_11; pfam08279
1132507007498	WYL domain; Region: WYL; pfam13280
1132507007499	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
1132507007500	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1132507007501	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1132507007502	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1132507007503	Protein export membrane protein; Region: SecD_SecF; pfam02355
1132507007504	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1132507007505	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1132507007506	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1132507007507	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1132507007508	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1132507007509	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1132507007510	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1132507007511	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1132507007512	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1132507007513	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1132507007514	peroxidase; Provisional; Region: PRK15000
1132507007515	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1132507007516	dimer interface [polypeptide binding]; other site
1132507007517	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1132507007518	catalytic triad [active]
1132507007519	peroxidatic and resolving cysteines [active]
1132507007520	maltodextrin glucosidase; Provisional; Region: PRK10785
1132507007521	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1132507007522	homodimer interface [polypeptide binding]; other site
1132507007523	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1132507007524	active site
1132507007525	homodimer interface [polypeptide binding]; other site
1132507007526	catalytic site [active]
1132507007527	putative proline-specific permease; Provisional; Region: proY; PRK10580
1132507007528	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507007529	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1132507007530	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1132507007531	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1132507007532	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1132507007533	putative active site [active]
1132507007534	heme pocket [chemical binding]; other site
1132507007535	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507007536	dimer interface [polypeptide binding]; other site
1132507007537	phosphorylation site [posttranslational modification]
1132507007538	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507007539	ATP binding site [chemical binding]; other site
1132507007540	Mg2+ binding site [ion binding]; other site
1132507007541	G-X-G motif; other site
1132507007542	transcriptional regulator PhoB; Provisional; Region: PRK10161
1132507007543	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507007544	active site
1132507007545	phosphorylation site [posttranslational modification]
1132507007546	intermolecular recognition site; other site
1132507007547	dimerization interface [polypeptide binding]; other site
1132507007548	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507007549	DNA binding site [nucleotide binding]
1132507007550	exonuclease subunit SbcD; Provisional; Region: PRK10966
1132507007551	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1132507007552	active site
1132507007553	metal binding site [ion binding]; metal-binding site
1132507007554	DNA binding site [nucleotide binding]
1132507007555	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1132507007556	exonuclease subunit SbcC; Provisional; Region: PRK10246
1132507007557	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507007558	Walker A/P-loop; other site
1132507007559	ATP binding site [chemical binding]; other site
1132507007560	Q-loop/lid; other site
1132507007561	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507007562	ABC transporter signature motif; other site
1132507007563	Walker B; other site
1132507007564	D-loop; other site
1132507007565	H-loop/switch region; other site
1132507007566	fructokinase; Reviewed; Region: PRK09557
1132507007567	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1132507007568	nucleotide binding site [chemical binding]; other site
1132507007569	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
1132507007570	hypothetical protein; Provisional; Region: PRK10579
1132507007571	hypothetical protein; Provisional; Region: PRK10481
1132507007572	hypothetical protein; Provisional; Region: PRK10380
1132507007573	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1132507007574	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1132507007575	ADP binding site [chemical binding]; other site
1132507007576	magnesium binding site [ion binding]; other site
1132507007577	putative shikimate binding site; other site
1132507007578	hypothetical protein; Validated; Region: PRK00124
1132507007579	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1132507007580	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1132507007581	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
1132507007582	MASE2 domain; Region: MASE2; pfam05230
1132507007583	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507007584	metal binding site [ion binding]; metal-binding site
1132507007585	active site
1132507007586	I-site; other site
1132507007587	hypothetical protein; Provisional; Region: PRK11505
1132507007588	psiF repeat; Region: PsiF_repeat; pfam07769
1132507007589	psiF repeat; Region: PsiF_repeat; pfam07769
1132507007590	anti-RssB factor; Provisional; Region: PRK10244
1132507007591	drug efflux system protein MdtG; Provisional; Region: PRK09874
1132507007592	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507007593	putative substrate translocation pore; other site
1132507007594	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
1132507007595	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
1132507007596	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1132507007597	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1132507007598	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1132507007599	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
1132507007600	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
1132507007601	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1132507007602	microcin B17 transporter; Reviewed; Region: PRK11098
1132507007603	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1132507007604	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1132507007605	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1132507007606	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1132507007607	ligand binding site [chemical binding]; other site
1132507007608	flexible hinge region; other site
1132507007609	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
1132507007610	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1132507007611	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1132507007612	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1132507007613	dimer interface [polypeptide binding]; other site
1132507007614	active site
1132507007615	Schiff base residues; other site
1132507007616	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
1132507007617	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1132507007618	acyl-activating enzyme (AAE) consensus motif; other site
1132507007619	AMP binding site [chemical binding]; other site
1132507007620	active site
1132507007621	CoA binding site [chemical binding]; other site
1132507007622	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1132507007623	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1132507007624	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1132507007625	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
1132507007626	dimer interface [polypeptide binding]; other site
1132507007627	active site
1132507007628	citrylCoA binding site [chemical binding]; other site
1132507007629	oxalacetate/citrate binding site [chemical binding]; other site
1132507007630	coenzyme A binding site [chemical binding]; other site
1132507007631	catalytic triad [active]
1132507007632	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1132507007633	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1132507007634	tetramer interface [polypeptide binding]; other site
1132507007635	active site
1132507007636	Mg2+/Mn2+ binding site [ion binding]; other site
1132507007637	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1132507007638	Propionate catabolism activator; Region: PrpR_N; pfam06506
1132507007639	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507007640	Walker A motif; other site
1132507007641	ATP binding site [chemical binding]; other site
1132507007642	Walker B motif; other site
1132507007643	arginine finger; other site
1132507007644	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1132507007645	hypothetical protein; Provisional; Region: PRK09929
1132507007646	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
1132507007647	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1132507007648	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1132507007649	N-terminal plug; other site
1132507007650	ligand-binding site [chemical binding]; other site
1132507007651	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1132507007652	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1132507007653	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1132507007654	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1132507007655	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1132507007656	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
1132507007657	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1132507007658	VRR-NUC domain; Region: VRR_NUC; pfam08774
1132507007659	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1132507007660	ATP binding site [chemical binding]; other site
1132507007661	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1132507007662	DNA methylase; Region: N6_N4_Mtase; cl17433
1132507007663	DNA methylase; Region: N6_N4_Mtase; pfam01555
1132507007664	putative sialic acid transporter; Region: 2A0112; TIGR00891
1132507007665	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507007666	putative substrate translocation pore; other site
1132507007667	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1132507007668	metal-binding site [ion binding]
1132507007669	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1132507007670	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1132507007671	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1132507007672	DNA binding residues [nucleotide binding]
1132507007673	dimerization interface [polypeptide binding]; other site
1132507007674	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1132507007675	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1132507007676	DNA binding site [nucleotide binding]
1132507007677	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1132507007678	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507007679	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1132507007680	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1132507007681	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507007682	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507007683	fimbrial outer membrane usher protein StbC; Provisional; Region: PRK15248
1132507007684	PapC N-terminal domain; Region: PapC_N; pfam13954
1132507007685	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1132507007686	PapC C-terminal domain; Region: PapC_C; pfam13953
1132507007687	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
1132507007688	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
1132507007689	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507007690	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507007691	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1132507007692	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1132507007693	putative catalytic cysteine [active]
1132507007694	gamma-glutamyl kinase; Provisional; Region: PRK05429
1132507007695	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1132507007696	nucleotide binding site [chemical binding]; other site
1132507007697	homotetrameric interface [polypeptide binding]; other site
1132507007698	putative phosphate binding site [ion binding]; other site
1132507007699	putative allosteric binding site; other site
1132507007700	PUA domain; Region: PUA; pfam01472
1132507007701	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1132507007702	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1132507007703	trimer interface [polypeptide binding]; other site
1132507007704	eyelet of channel; other site
1132507007705	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1132507007706	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1132507007707	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1132507007708	active site
1132507007709	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1132507007710	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1132507007711	metal binding site [ion binding]; metal-binding site
1132507007712	dimer interface [polypeptide binding]; other site
1132507007713	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1132507007714	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1132507007715	hypothetical protein; Reviewed; Region: PRK09588
1132507007716	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
1132507007717	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1132507007718	active site
1132507007719	DNA polymerase IV; Validated; Region: PRK02406
1132507007720	DNA binding site [nucleotide binding]
1132507007721	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1132507007722	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1132507007723	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1132507007724	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1132507007725	putative active site [active]
1132507007726	putative dimer interface [polypeptide binding]; other site
1132507007727	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1132507007728	dimer interface [polypeptide binding]; other site
1132507007729	active site
1132507007730	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1132507007731	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1132507007732	active site
1132507007733	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1132507007734	C-N hydrolase family amidase; Provisional; Region: PRK10438
1132507007735	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1132507007736	putative active site [active]
1132507007737	catalytic triad [active]
1132507007738	dimer interface [polypeptide binding]; other site
1132507007739	multimer interface [polypeptide binding]; other site
1132507007740	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1132507007741	dimer interface [polypeptide binding]; other site
1132507007742	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1132507007743	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1132507007744	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
1132507007745	AsnC family; Region: AsnC_trans_reg; pfam01037
1132507007746	putative fimbrial protein TcfD; Provisional; Region: PRK15311
1132507007747	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
1132507007748	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; cl04524
1132507007749	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1132507007750	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1132507007751	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1132507007752	Transposase; Region: HTH_Tnp_1; cl17663
1132507007753	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507007754	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507007755	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1132507007756	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
1132507007757	putative active site [active]
1132507007758	putative metal binding site [ion binding]; other site
1132507007759	putative pilin structural protein SafD; Provisional; Region: PRK15222
1132507007760	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
1132507007761	PapC N-terminal domain; Region: PapC_N; pfam13954
1132507007762	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1132507007763	PapC C-terminal domain; Region: PapC_C; pfam13953
1132507007764	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
1132507007765	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507007766	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507007767	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1132507007768	Integrase core domain; Region: rve_3; pfam13683
1132507007769	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
1132507007770	RHS Repeat; Region: RHS_repeat; cl11982
1132507007771	RHS Repeat; Region: RHS_repeat; pfam05593
1132507007772	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1132507007773	RHS Repeat; Region: RHS_repeat; pfam05593
1132507007774	RHS Repeat; Region: RHS_repeat; pfam05593
1132507007775	RHS Repeat; Region: RHS_repeat; pfam05593
1132507007776	RHS Repeat; Region: RHS_repeat; pfam05593
1132507007777	RHS protein; Region: RHS; pfam03527
1132507007778	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1132507007779	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
1132507007780	PAAR motif; Region: PAAR_motif; pfam05488
1132507007781	RHS Repeat; Region: RHS_repeat; cl11982
1132507007782	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1132507007783	RHS Repeat; Region: RHS_repeat; pfam05593
1132507007784	RHS Repeat; Region: RHS_repeat; pfam05593
1132507007785	RHS protein; Region: RHS; pfam03527
1132507007786	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1132507007787	A nuclease family of the HNH/ENDO VII superfamily with conserved AHH; Region: AHH; pfam14412
1132507007788	Uncharacterized conserved protein [Function unknown]; Region: COG5435
1132507007789	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501
1132507007790	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1132507007791	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1132507007792	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4893
1132507007793	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
1132507007794	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; cl01611
1132507007795	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
1132507007796	hypothetical protein; Provisional; Region: PRK08126
1132507007797	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
1132507007798	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1132507007799	ligand binding site [chemical binding]; other site
1132507007800	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
1132507007801	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1132507007802	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
1132507007803	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1132507007804	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
1132507007805	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1132507007806	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507007807	Walker A motif; other site
1132507007808	ATP binding site [chemical binding]; other site
1132507007809	Walker B motif; other site
1132507007810	arginine finger; other site
1132507007811	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507007812	Walker A motif; other site
1132507007813	ATP binding site [chemical binding]; other site
1132507007814	Walker B motif; other site
1132507007815	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1132507007816	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
1132507007817	ImpE protein; Region: ImpE; pfam07024
1132507007818	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
1132507007819	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1132507007820	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1132507007821	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
1132507007822	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1132507007823	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1132507007824	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1132507007825	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1132507007826	active site
1132507007827	catalytic site [active]
1132507007828	substrate binding site [chemical binding]; other site
1132507007829	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1132507007830	RNA/DNA hybrid binding site [nucleotide binding]; other site
1132507007831	active site
1132507007832	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507007833	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1132507007834	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1132507007835	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1132507007836	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1132507007837	catalytic residue [active]
1132507007838	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1132507007839	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1132507007840	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1132507007841	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1132507007842	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1132507007843	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507007844	S-adenosylmethionine binding site [chemical binding]; other site
1132507007845	hypothetical protein; Provisional; Region: PRK05421
1132507007846	putative catalytic site [active]
1132507007847	putative metal binding site [ion binding]; other site
1132507007848	putative phosphate binding site [ion binding]; other site
1132507007849	putative catalytic site [active]
1132507007850	putative phosphate binding site [ion binding]; other site
1132507007851	putative metal binding site [ion binding]; other site
1132507007852	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1132507007853	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507007854	putative substrate translocation pore; other site
1132507007855	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507007856	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507007857	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
1132507007858	putative effector binding pocket; other site
1132507007859	dimerization interface [polypeptide binding]; other site
1132507007860	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1132507007861	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1132507007862	active site
1132507007863	catalytic tetrad [active]
1132507007864	protein disaggregation chaperone; Provisional; Region: PRK10865
1132507007865	Clp amino terminal domain; Region: Clp_N; pfam02861
1132507007866	Clp amino terminal domain; Region: Clp_N; pfam02861
1132507007867	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507007868	Walker A motif; other site
1132507007869	ATP binding site [chemical binding]; other site
1132507007870	Walker B motif; other site
1132507007871	arginine finger; other site
1132507007872	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507007873	Walker A motif; other site
1132507007874	ATP binding site [chemical binding]; other site
1132507007875	Walker B motif; other site
1132507007876	arginine finger; other site
1132507007877	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1132507007878	hypothetical protein; Provisional; Region: PRK10723
1132507007879	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1132507007880	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1132507007881	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1132507007882	RNA binding surface [nucleotide binding]; other site
1132507007883	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1132507007884	active site
1132507007885	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1132507007886	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1132507007887	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1132507007888	30S subunit binding site; other site
1132507007889	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1132507007890	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1132507007891	Prephenate dehydratase; Region: PDT; pfam00800
1132507007892	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1132507007893	putative L-Phe binding site [chemical binding]; other site
1132507007894	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1132507007895	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1132507007896	Chorismate mutase type II; Region: CM_2; cl00693
1132507007897	prephenate dehydrogenase; Validated; Region: PRK08507
1132507007898	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1132507007899	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1132507007900	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1132507007901	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1132507007902	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507007903	metal binding site [ion binding]; metal-binding site
1132507007904	active site
1132507007905	I-site; other site
1132507007906	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1132507007907	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1132507007908	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1132507007909	RimM N-terminal domain; Region: RimM; pfam01782
1132507007910	PRC-barrel domain; Region: PRC; pfam05239
1132507007911	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1132507007912	signal recognition particle protein; Provisional; Region: PRK10867
1132507007913	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1132507007914	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1132507007915	P loop; other site
1132507007916	GTP binding site [chemical binding]; other site
1132507007917	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1132507007918	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1132507007919	hypothetical protein; Provisional; Region: PRK11573
1132507007920	Domain of unknown function DUF21; Region: DUF21; pfam01595
1132507007921	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1132507007922	Transporter associated domain; Region: CorC_HlyC; smart01091
1132507007923	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1132507007924	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1132507007925	dimer interface [polypeptide binding]; other site
1132507007926	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1132507007927	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1132507007928	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1132507007929	recombination and repair protein; Provisional; Region: PRK10869
1132507007930	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1132507007931	Walker A/P-loop; other site
1132507007932	ATP binding site [chemical binding]; other site
1132507007933	Q-loop/lid; other site
1132507007934	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1132507007935	ABC transporter signature motif; other site
1132507007936	Walker B; other site
1132507007937	D-loop; other site
1132507007938	H-loop/switch region; other site
1132507007939	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1132507007940	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1132507007941	hypothetical protein; Validated; Region: PRK01777
1132507007942	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1132507007943	putative coenzyme Q binding site [chemical binding]; other site
1132507007944	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1132507007945	SmpB-tmRNA interface; other site
1132507007946	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507007947	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507007948	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507007949	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507007950	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507007951	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507007952	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1132507007953	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507007954	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507007955	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1132507007956	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507007957	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507007958	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
1132507007959	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1132507007960	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1132507007961	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1132507007962	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507007963	Walker A/P-loop; other site
1132507007964	ATP binding site [chemical binding]; other site
1132507007965	Q-loop/lid; other site
1132507007966	ABC transporter signature motif; other site
1132507007967	Walker B; other site
1132507007968	D-loop; other site
1132507007969	H-loop/switch region; other site
1132507007970	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1132507007971	HlyD family secretion protein; Region: HlyD_3; pfam13437
1132507007972	RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons; Region: RT_like; cl02808
1132507007973	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1132507007974	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1132507007975	tail protein; Provisional; Region: D; PHA02561
1132507007976	Phage protein U [General function prediction only]; Region: COG3499
1132507007977	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1132507007978	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1132507007979	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1132507007980	major tail tube protein; Provisional; Region: FII; PHA02600
1132507007981	major tail sheath protein; Provisional; Region: FI; PHA02560
1132507007982	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1132507007983	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1132507007984	catalytic residues [active]
1132507007985	catalytic nucleophile [active]
1132507007986	Presynaptic Site I dimer interface [polypeptide binding]; other site
1132507007987	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1132507007988	Synaptic Flat tetramer interface [polypeptide binding]; other site
1132507007989	Synaptic Site I dimer interface [polypeptide binding]; other site
1132507007990	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1132507007991	DNA-binding interface [nucleotide binding]; DNA binding site
1132507007992	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
1132507007993	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1132507007994	homodimer interface [polypeptide binding]; other site
1132507007995	active site
1132507007996	TDP-binding site; other site
1132507007997	acceptor substrate-binding pocket; other site
1132507007998	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1132507007999	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507008000	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1132507008001	Walker A/P-loop; other site
1132507008002	ATP binding site [chemical binding]; other site
1132507008003	Q-loop/lid; other site
1132507008004	ABC transporter signature motif; other site
1132507008005	Walker B; other site
1132507008006	D-loop; other site
1132507008007	H-loop/switch region; other site
1132507008008	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1132507008009	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1132507008010	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507008011	Walker A/P-loop; other site
1132507008012	ATP binding site [chemical binding]; other site
1132507008013	Q-loop/lid; other site
1132507008014	ABC transporter signature motif; other site
1132507008015	Walker B; other site
1132507008016	D-loop; other site
1132507008017	H-loop/switch region; other site
1132507008018	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1132507008019	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1132507008020	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1132507008021	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1132507008022	outer membrane receptor FepA; Provisional; Region: PRK13528
1132507008023	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1132507008024	N-terminal plug; other site
1132507008025	ligand-binding site [chemical binding]; other site
1132507008026	secreted effector protein PipB2; Provisional; Region: PRK15196
1132507008027	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1132507008028	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1132507008029	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1132507008030	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1132507008031	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1132507008032	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
1132507008033	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
1132507008034	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1132507008035	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1132507008036	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
1132507008037	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1132507008038	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1132507008039	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507008040	dimer interface [polypeptide binding]; other site
1132507008041	phosphorylation site [posttranslational modification]
1132507008042	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507008043	ATP binding site [chemical binding]; other site
1132507008044	Mg2+ binding site [ion binding]; other site
1132507008045	G-X-G motif; other site
1132507008046	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
1132507008047	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507008048	active site
1132507008049	phosphorylation site [posttranslational modification]
1132507008050	intermolecular recognition site; other site
1132507008051	dimerization interface [polypeptide binding]; other site
1132507008052	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507008053	DNA binding site [nucleotide binding]
1132507008054	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1132507008055	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
1132507008056	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
1132507008057	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
1132507008058	substrate binding pocket [chemical binding]; other site
1132507008059	active site
1132507008060	iron coordination sites [ion binding]; other site
1132507008061	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1132507008062	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1132507008063	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
1132507008064	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1132507008065	tetramerization interface [polypeptide binding]; other site
1132507008066	NAD(P) binding site [chemical binding]; other site
1132507008067	catalytic residues [active]
1132507008068	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
1132507008069	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1132507008070	inhibitor-cofactor binding pocket; inhibition site
1132507008071	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507008072	catalytic residue [active]
1132507008073	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
1132507008074	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507008075	DNA-binding site [nucleotide binding]; DNA binding site
1132507008076	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1132507008077	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1132507008078	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1132507008079	dimerization interface [polypeptide binding]; other site
1132507008080	putative DNA binding site [nucleotide binding]; other site
1132507008081	putative Zn2+ binding site [ion binding]; other site
1132507008082	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1132507008083	active site residue [active]
1132507008084	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1132507008085	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1132507008086	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1132507008087	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1132507008088	hypothetical protein; Provisional; Region: PRK10556
1132507008089	hypothetical protein; Provisional; Region: PRK10132
1132507008090	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1132507008091	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1132507008092	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1132507008093	catalytic residues [active]
1132507008094	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1132507008095	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1132507008096	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1132507008097	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1132507008098	active site
1132507008099	dimer interface [polypeptide binding]; other site
1132507008100	catalytic residues [active]
1132507008101	effector binding site; other site
1132507008102	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1132507008103	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1132507008104	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1132507008105	dimer interface [polypeptide binding]; other site
1132507008106	putative radical transfer pathway; other site
1132507008107	diiron center [ion binding]; other site
1132507008108	tyrosyl radical; other site
1132507008109	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1132507008110	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507008111	dimer interface [polypeptide binding]; other site
1132507008112	conserved gate region; other site
1132507008113	putative PBP binding loops; other site
1132507008114	ABC-ATPase subunit interface; other site
1132507008115	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1132507008116	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1132507008117	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1132507008118	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008119	transcriptional repressor MprA; Provisional; Region: PRK10870
1132507008120	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1132507008121	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1132507008122	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1132507008123	HlyD family secretion protein; Region: HlyD_3; pfam13437
1132507008124	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1132507008125	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008126	putative substrate translocation pore; other site
1132507008127	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008128	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1132507008129	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1132507008130	glutamate--cysteine ligase; Provisional; Region: PRK02107
1132507008131	Predicted membrane protein [Function unknown]; Region: COG1238
1132507008132	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1132507008133	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507008134	motif II; other site
1132507008135	O-methyltransferase; Region: Methyltransf_2; pfam00891
1132507008136	carbon storage regulator; Provisional; Region: PRK01712
1132507008137	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1132507008138	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1132507008139	motif 1; other site
1132507008140	active site
1132507008141	motif 2; other site
1132507008142	motif 3; other site
1132507008143	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1132507008144	DHHA1 domain; Region: DHHA1; pfam02272
1132507008145	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1132507008146	recombinase A; Provisional; Region: recA; PRK09354
1132507008147	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1132507008148	hexamer interface [polypeptide binding]; other site
1132507008149	Walker A motif; other site
1132507008150	ATP binding site [chemical binding]; other site
1132507008151	Walker B motif; other site
1132507008152	hypothetical protein; Validated; Region: PRK03661
1132507008153	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1132507008154	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1132507008155	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1132507008156	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
1132507008157	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1132507008158	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1132507008159	Nucleoside recognition; Region: Gate; pfam07670
1132507008160	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1132507008161	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1132507008162	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1132507008163	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1132507008164	putative NAD(P) binding site [chemical binding]; other site
1132507008165	active site
1132507008166	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1132507008167	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1132507008168	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1132507008169	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507008170	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1132507008171	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1132507008172	putative active site [active]
1132507008173	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1132507008174	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1132507008175	GAF domain; Region: GAF; pfam01590
1132507008176	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507008177	Walker A motif; other site
1132507008178	ATP binding site [chemical binding]; other site
1132507008179	Walker B motif; other site
1132507008180	arginine finger; other site
1132507008181	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1132507008182	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1132507008183	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1132507008184	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1132507008185	iron binding site [ion binding]; other site
1132507008186	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1132507008187	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1132507008188	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507008189	Acylphosphatase; Region: Acylphosphatase; pfam00708
1132507008190	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1132507008191	HypF finger; Region: zf-HYPF; pfam07503
1132507008192	HypF finger; Region: zf-HYPF; pfam07503
1132507008193	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1132507008194	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1132507008195	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1132507008196	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1132507008197	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1132507008198	nickel binding site [ion binding]; other site
1132507008199	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1132507008200	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1132507008201	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1132507008202	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1132507008203	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1132507008204	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1132507008205	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1132507008206	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1132507008207	NADH dehydrogenase; Region: NADHdh; cl00469
1132507008208	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1132507008209	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1132507008210	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1132507008211	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
1132507008212	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1132507008213	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1132507008214	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1132507008215	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1132507008216	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1132507008217	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1132507008218	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1132507008219	dimerization interface [polypeptide binding]; other site
1132507008220	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1132507008221	ATP binding site [chemical binding]; other site
1132507008222	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1132507008223	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1132507008224	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1132507008225	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507008226	Walker A motif; other site
1132507008227	ATP binding site [chemical binding]; other site
1132507008228	Walker B motif; other site
1132507008229	arginine finger; other site
1132507008230	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1132507008231	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1132507008232	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1132507008233	metal binding site [ion binding]; metal-binding site
1132507008234	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1132507008235	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1132507008236	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1132507008237	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1132507008238	ABC-ATPase subunit  interface; other site
1132507008239	dimer interface [polypeptide binding]; other site
1132507008240	putative PBP binding regions; other site
1132507008241	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1132507008242	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1132507008243	ABC-ATPase subunit  interface; other site
1132507008244	dimer interface [polypeptide binding]; other site
1132507008245	putative PBP binding regions; other site
1132507008246	transcriptional activator SprB; Provisional; Region: PRK15320
1132507008247	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1132507008248	transcriptional regulator SirC; Provisional; Region: PRK15044
1132507008249	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507008250	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
1132507008251	invasion protein OrgB; Provisional; Region: PRK15322
1132507008252	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
1132507008253	invasion protein OrgA; Provisional; Region: PRK15323
1132507008254	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
1132507008255	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
1132507008256	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
1132507008257	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
1132507008258	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
1132507008259	transcriptional regulator HilD; Provisional; Region: PRK15185
1132507008260	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507008261	invasion protein regulator; Provisional; Region: PRK12370
1132507008262	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507008263	DNA binding site [nucleotide binding]
1132507008264	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1132507008265	binding surface
1132507008266	TPR motif; other site
1132507008267	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1132507008268	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1132507008269	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1132507008270	catalytic residue [active]
1132507008271	chaperone protein SicP; Provisional; Region: PRK15329
1132507008272	putative acyl carrier protein IacP; Validated; Region: PRK08172
1132507008273	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
1132507008274	cell invasion protein SipD; Provisional; Region: PRK15330
1132507008275	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
1132507008276	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
1132507008277	chaperone protein SicA; Provisional; Region: PRK15331
1132507008278	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1132507008279	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1132507008280	type III secretion system protein SpaS; Validated; Region: PRK08156
1132507008281	type III secretion system protein SpaR; Provisional; Region: PRK15332
1132507008282	type III secretion system protein SpaQ; Provisional; Region: PRK15333
1132507008283	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
1132507008284	type III secretion system protein SpaO; Validated; Region: PRK08158
1132507008285	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1132507008286	antigen presentation protein SpaN; Provisional; Region: PRK15334
1132507008287	Surface presentation of antigens protein; Region: SPAN; pfam02510
1132507008288	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
1132507008289	ATP synthase SpaL; Validated; Region: PRK08149
1132507008290	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1132507008291	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1132507008292	Walker A motif; other site
1132507008293	ATP binding site [chemical binding]; other site
1132507008294	Walker B motif; other site
1132507008295	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
1132507008296	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
1132507008297	type III secretion system protein InvA; Provisional; Region: PRK15337
1132507008298	type III secretion system regulator InvE; Provisional; Region: PRK15338
1132507008299	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
1132507008300	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
1132507008301	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1132507008302	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1132507008303	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1132507008304	transcriptional regulator InvF; Provisional; Region: PRK15340
1132507008305	InvH outer membrane lipoprotein; Region: InvH; pfam04741
1132507008306	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1132507008307	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1132507008308	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1132507008309	active site
1132507008310	metal binding site [ion binding]; metal-binding site
1132507008311	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1132507008312	MutS domain I; Region: MutS_I; pfam01624
1132507008313	MutS domain II; Region: MutS_II; pfam05188
1132507008314	MutS domain III; Region: MutS_III; pfam05192
1132507008315	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1132507008316	Walker A/P-loop; other site
1132507008317	ATP binding site [chemical binding]; other site
1132507008318	Q-loop/lid; other site
1132507008319	ABC transporter signature motif; other site
1132507008320	Walker B; other site
1132507008321	D-loop; other site
1132507008322	H-loop/switch region; other site
1132507008323	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1132507008324	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008325	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1132507008326	putative substrate translocation pore; other site
1132507008327	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507008328	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507008329	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1132507008330	putative effector binding pocket; other site
1132507008331	dimerization interface [polypeptide binding]; other site
1132507008332	GntP family permease; Region: GntP_permease; pfam02447
1132507008333	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1132507008334	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1132507008335	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
1132507008336	putative NAD(P) binding site [chemical binding]; other site
1132507008337	active site
1132507008338	putative substrate binding site [chemical binding]; other site
1132507008339	hypothetical protein; Provisional; Region: PRK09989
1132507008340	putative aldolase; Validated; Region: PRK08130
1132507008341	intersubunit interface [polypeptide binding]; other site
1132507008342	active site
1132507008343	Zn2+ binding site [ion binding]; other site
1132507008344	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1132507008345	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1132507008346	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1132507008347	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1132507008348	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507008349	MarR family; Region: MarR_2; cl17246
1132507008350	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1132507008351	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1132507008352	Flavoprotein; Region: Flavoprotein; pfam02441
1132507008353	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1132507008354	RNA polymerase sigma factor RpoS; Region: rpoS_proteo; TIGR02394
1132507008355	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1132507008356	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1132507008357	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1132507008358	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1132507008359	DNA binding residues [nucleotide binding]
1132507008360	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1132507008361	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1132507008362	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
1132507008363	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1132507008364	Peptidase family M23; Region: Peptidase_M23; pfam01551
1132507008365	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1132507008366	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507008367	S-adenosylmethionine binding site [chemical binding]; other site
1132507008368	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1132507008369	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1132507008370	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1132507008371	Permutation of conserved domain; other site
1132507008372	active site
1132507008373	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1132507008374	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1132507008375	homotrimer interaction site [polypeptide binding]; other site
1132507008376	zinc binding site [ion binding]; other site
1132507008377	CDP-binding sites; other site
1132507008378	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1132507008379	substrate binding site; other site
1132507008380	dimer interface; other site
1132507008381	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1132507008382	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1132507008383	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
1132507008384	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1132507008385	ligand-binding site [chemical binding]; other site
1132507008386	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1132507008387	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1132507008388	CysD dimerization site [polypeptide binding]; other site
1132507008389	G1 box; other site
1132507008390	putative GEF interaction site [polypeptide binding]; other site
1132507008391	GTP/Mg2+ binding site [chemical binding]; other site
1132507008392	Switch I region; other site
1132507008393	G2 box; other site
1132507008394	G3 box; other site
1132507008395	Switch II region; other site
1132507008396	G4 box; other site
1132507008397	G5 box; other site
1132507008398	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1132507008399	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1132507008400	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1132507008401	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1132507008402	Active Sites [active]
1132507008403	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1132507008404	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1132507008405	metal binding site [ion binding]; metal-binding site
1132507008406	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09755
1132507008407	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
1132507008408	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
1132507008409	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
1132507008410	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
1132507008411	CT1975-like protein; Region: Cas_CT1975; pfam09344
1132507008412	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
1132507008413	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
1132507008414	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1132507008415	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1132507008416	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1132507008417	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
1132507008418	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1132507008419	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1132507008420	Active Sites [active]
1132507008421	sulfite reductase subunit beta; Provisional; Region: PRK13504
1132507008422	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1132507008423	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1132507008424	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1132507008425	Flavodoxin; Region: Flavodoxin_1; pfam00258
1132507008426	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1132507008427	FAD binding pocket [chemical binding]; other site
1132507008428	FAD binding motif [chemical binding]; other site
1132507008429	catalytic residues [active]
1132507008430	NAD binding pocket [chemical binding]; other site
1132507008431	phosphate binding motif [ion binding]; other site
1132507008432	beta-alpha-beta structure motif; other site
1132507008433	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1132507008434	active site
1132507008435	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
1132507008436	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1132507008437	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1132507008438	enolase; Provisional; Region: eno; PRK00077
1132507008439	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1132507008440	dimer interface [polypeptide binding]; other site
1132507008441	metal binding site [ion binding]; metal-binding site
1132507008442	substrate binding pocket [chemical binding]; other site
1132507008443	CTP synthetase; Validated; Region: pyrG; PRK05380
1132507008444	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1132507008445	Catalytic site [active]
1132507008446	active site
1132507008447	UTP binding site [chemical binding]; other site
1132507008448	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1132507008449	active site
1132507008450	putative oxyanion hole; other site
1132507008451	catalytic triad [active]
1132507008452	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1132507008453	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1132507008454	homodimer interface [polypeptide binding]; other site
1132507008455	metal binding site [ion binding]; metal-binding site
1132507008456	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1132507008457	homodimer interface [polypeptide binding]; other site
1132507008458	active site
1132507008459	putative chemical substrate binding site [chemical binding]; other site
1132507008460	metal binding site [ion binding]; metal-binding site
1132507008461	putative fimbrial outer membrane usher protein SteB; Provisional; Region: PRK15273
1132507008462	PapC N-terminal domain; Region: PapC_N; pfam13954
1132507008463	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1132507008464	PapC C-terminal domain; Region: PapC_C; pfam13953
1132507008465	putative periplasmic fimbrial chaperone protein SteC; Provisional; Region: PRK15274
1132507008466	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507008467	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507008468	putative fimbrial protein SteD; Provisional; Region: PRK15275
1132507008469	putative fimbrial subunit SteE; Provisional; Region: PRK15276
1132507008470	fimbrial protein SteF; Provisional; Region: PRK15260
1132507008471	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1132507008472	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
1132507008473	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1132507008474	HD domain; Region: HD_4; pfam13328
1132507008475	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1132507008476	synthetase active site [active]
1132507008477	NTP binding site [chemical binding]; other site
1132507008478	metal binding site [ion binding]; metal-binding site
1132507008479	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1132507008480	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1132507008481	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1132507008482	TRAM domain; Region: TRAM; pfam01938
1132507008483	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507008484	S-adenosylmethionine binding site [chemical binding]; other site
1132507008485	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1132507008486	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1132507008487	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507008488	dimerization interface [polypeptide binding]; other site
1132507008489	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507008490	dimer interface [polypeptide binding]; other site
1132507008491	phosphorylation site [posttranslational modification]
1132507008492	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507008493	ATP binding site [chemical binding]; other site
1132507008494	Mg2+ binding site [ion binding]; other site
1132507008495	G-X-G motif; other site
1132507008496	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1132507008497	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507008498	active site
1132507008499	phosphorylation site [posttranslational modification]
1132507008500	intermolecular recognition site; other site
1132507008501	dimerization interface [polypeptide binding]; other site
1132507008502	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1132507008503	putative binding surface; other site
1132507008504	active site
1132507008505	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1132507008506	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1132507008507	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1132507008508	active site
1132507008509	tetramer interface [polypeptide binding]; other site
1132507008510	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1132507008511	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1132507008512	active site
1132507008513	tetramer interface [polypeptide binding]; other site
1132507008514	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008515	D-galactonate transporter; Region: 2A0114; TIGR00893
1132507008516	putative substrate translocation pore; other site
1132507008517	flavodoxin; Provisional; Region: PRK08105
1132507008518	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1132507008519	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1132507008520	probable active site [active]
1132507008521	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
1132507008522	SecY interacting protein Syd; Provisional; Region: PRK04968
1132507008523	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1132507008524	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1132507008525	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1132507008526	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1132507008527	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1132507008528	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1132507008529	serine transporter; Region: stp; TIGR00814
1132507008530	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1132507008531	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1132507008532	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1132507008533	flap endonuclease-like protein; Provisional; Region: PRK09482
1132507008534	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1132507008535	active site
1132507008536	metal binding site 1 [ion binding]; metal-binding site
1132507008537	putative 5' ssDNA interaction site; other site
1132507008538	metal binding site 3; metal-binding site
1132507008539	metal binding site 2 [ion binding]; metal-binding site
1132507008540	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1132507008541	putative DNA binding site [nucleotide binding]; other site
1132507008542	putative metal binding site [ion binding]; other site
1132507008543	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1132507008544	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1132507008545	dimer interface [polypeptide binding]; other site
1132507008546	active site
1132507008547	metal binding site [ion binding]; metal-binding site
1132507008548	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1132507008549	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1132507008550	intersubunit interface [polypeptide binding]; other site
1132507008551	active site
1132507008552	Zn2+ binding site [ion binding]; other site
1132507008553	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1132507008554	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008555	putative substrate translocation pore; other site
1132507008556	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1132507008557	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
1132507008558	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1132507008559	trimer interface [polypeptide binding]; other site
1132507008560	substrate binding site [chemical binding]; other site
1132507008561	Mn binding site [ion binding]; other site
1132507008562	L-fuculokinase; Provisional; Region: PRK10331
1132507008563	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1132507008564	nucleotide binding site [chemical binding]; other site
1132507008565	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
1132507008566	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1132507008567	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1132507008568	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507008569	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1132507008570	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1132507008571	hypothetical protein; Provisional; Region: PRK10873
1132507008572	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1132507008573	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507008574	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1132507008575	dimerization interface [polypeptide binding]; other site
1132507008576	substrate binding pocket [chemical binding]; other site
1132507008577	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1132507008578	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1132507008579	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1132507008580	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1132507008581	catalytic residue [active]
1132507008582	CsdA-binding activator; Provisional; Region: PRK15019
1132507008583	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1132507008584	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1132507008585	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1132507008586	putative ATP binding site [chemical binding]; other site
1132507008587	putative substrate interface [chemical binding]; other site
1132507008588	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1132507008589	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1132507008590	MltA specific insert domain; Region: MltA; pfam03562
1132507008591	3D domain; Region: 3D; pfam06725
1132507008592	AMIN domain; Region: AMIN; pfam11741
1132507008593	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1132507008594	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1132507008595	active site
1132507008596	metal binding site [ion binding]; metal-binding site
1132507008597	N-acetylglutamate synthase; Validated; Region: PRK05279
1132507008598	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1132507008599	putative feedback inhibition sensing region; other site
1132507008600	putative nucleotide binding site [chemical binding]; other site
1132507008601	putative substrate binding site [chemical binding]; other site
1132507008602	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507008603	Coenzyme A binding pocket [chemical binding]; other site
1132507008604	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1132507008605	AAA domain; Region: AAA_30; pfam13604
1132507008606	Family description; Region: UvrD_C_2; pfam13538
1132507008607	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1132507008608	protease3; Provisional; Region: PRK15101
1132507008609	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1132507008610	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1132507008611	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1132507008612	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1132507008613	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1132507008614	hypothetical protein; Provisional; Region: PRK10332
1132507008615	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1132507008616	hypothetical protein; Provisional; Region: PRK11521
1132507008617	hypothetical protein; Provisional; Region: PRK10557
1132507008618	hypothetical protein; Provisional; Region: PRK10506
1132507008619	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1132507008620	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507008621	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1132507008622	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1132507008623	dimerization interface [polypeptide binding]; other site
1132507008624	active site
1132507008625	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1132507008626	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1132507008627	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1132507008628	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1132507008629	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1132507008630	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1132507008631	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1132507008632	putative active site [active]
1132507008633	Ap4A binding site [chemical binding]; other site
1132507008634	nudix motif; other site
1132507008635	putative metal binding site [ion binding]; other site
1132507008636	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1132507008637	putative DNA-binding cleft [nucleotide binding]; other site
1132507008638	putative DNA clevage site; other site
1132507008639	molecular lever; other site
1132507008640	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1132507008641	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1132507008642	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1132507008643	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1132507008644	active site
1132507008645	catalytic tetrad [active]
1132507008646	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1132507008647	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008648	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1132507008649	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1132507008650	putative acyl-acceptor binding pocket; other site
1132507008651	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1132507008652	acyl-activating enzyme (AAE) consensus motif; other site
1132507008653	putative AMP binding site [chemical binding]; other site
1132507008654	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507008655	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1132507008656	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507008657	DNA binding site [nucleotide binding]
1132507008658	domain linker motif; other site
1132507008659	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1132507008660	dimerization interface (closed form) [polypeptide binding]; other site
1132507008661	ligand binding site [chemical binding]; other site
1132507008662	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1132507008663	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507008664	DNA binding site [nucleotide binding]
1132507008665	domain linker motif; other site
1132507008666	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1132507008667	dimerization interface (closed form) [polypeptide binding]; other site
1132507008668	ligand binding site [chemical binding]; other site
1132507008669	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1132507008670	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1132507008671	active site
1132507008672	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1132507008673	substrate binding site [chemical binding]; other site
1132507008674	catalytic residues [active]
1132507008675	dimer interface [polypeptide binding]; other site
1132507008676	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1132507008677	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507008678	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507008679	dimerization interface [polypeptide binding]; other site
1132507008680	putative racemase; Provisional; Region: PRK10200
1132507008681	aspartate racemase; Region: asp_race; TIGR00035
1132507008682	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1132507008683	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008684	putative substrate translocation pore; other site
1132507008685	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008686	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1132507008687	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1132507008688	NADP binding site [chemical binding]; other site
1132507008689	homodimer interface [polypeptide binding]; other site
1132507008690	active site
1132507008691	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1132507008692	putative acyltransferase; Provisional; Region: PRK05790
1132507008693	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1132507008694	dimer interface [polypeptide binding]; other site
1132507008695	active site
1132507008696	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507008697	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507008698	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1132507008699	dimerization interface [polypeptide binding]; other site
1132507008700	Predicted membrane protein [Function unknown]; Region: COG4125
1132507008701	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1132507008702	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1132507008703	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1132507008704	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1132507008705	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1132507008706	putative metal binding site [ion binding]; other site
1132507008707	putative homodimer interface [polypeptide binding]; other site
1132507008708	putative homotetramer interface [polypeptide binding]; other site
1132507008709	putative homodimer-homodimer interface [polypeptide binding]; other site
1132507008710	putative allosteric switch controlling residues; other site
1132507008711	transcriptional activator SprB; Provisional; Region: PRK15320
1132507008712	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14600
1132507008713	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
1132507008714	Fimbrial protein; Region: Fimbrial; pfam00419
1132507008715	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
1132507008716	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507008717	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507008718	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
1132507008719	PapC N-terminal domain; Region: PapC_N; pfam13954
1132507008720	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1132507008721	PapC C-terminal domain; Region: PapC_C; pfam13953
1132507008722	fimbrial protein StdA; Provisional; Region: PRK15210
1132507008723	hypothetical protein; Provisional; Region: PRK10316
1132507008724	YfdX protein; Region: YfdX; pfam10938
1132507008725	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1132507008726	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1132507008727	oligomeric interface; other site
1132507008728	putative active site [active]
1132507008729	homodimer interface [polypeptide binding]; other site
1132507008730	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
1132507008731	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1132507008732	INT_SG2, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 2, C-terminal catalytic domain. The CD contains mainly predicted integrase/recombinases and phage-related integrases. Some have N-terminal domains, which show little sequence...; Region: INT_SG2_C; cd01184
1132507008733	Int/Topo IB signature motif; other site
1132507008734	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1132507008735	Peptidase family M23; Region: Peptidase_M23; pfam01551
1132507008736	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1132507008737	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1132507008738	active site
1132507008739	metal binding site [ion binding]; metal-binding site
1132507008740	nudix motif; other site
1132507008741	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1132507008742	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1132507008743	dimer interface [polypeptide binding]; other site
1132507008744	putative anticodon binding site; other site
1132507008745	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1132507008746	motif 1; other site
1132507008747	active site
1132507008748	motif 2; other site
1132507008749	motif 3; other site
1132507008750	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1132507008751	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1132507008752	RF-1 domain; Region: RF-1; pfam00472
1132507008753	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1132507008754	DHH family; Region: DHH; pfam01368
1132507008755	DHHA1 domain; Region: DHHA1; pfam02272
1132507008756	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1132507008757	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1132507008758	dimerization domain [polypeptide binding]; other site
1132507008759	dimer interface [polypeptide binding]; other site
1132507008760	catalytic residues [active]
1132507008761	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1132507008762	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1132507008763	active site
1132507008764	Int/Topo IB signature motif; other site
1132507008765	flavodoxin FldB; Provisional; Region: PRK12359
1132507008766	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1132507008767	hypothetical protein; Provisional; Region: PRK10878
1132507008768	putative global regulator; Reviewed; Region: PRK09559
1132507008769	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1132507008770	hemolysin; Provisional; Region: PRK15087
1132507008771	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1132507008772	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1132507008773	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1132507008774	beta-galactosidase; Region: BGL; TIGR03356
1132507008775	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
1132507008776	glycine dehydrogenase; Provisional; Region: PRK05367
1132507008777	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1132507008778	tetramer interface [polypeptide binding]; other site
1132507008779	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507008780	catalytic residue [active]
1132507008781	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1132507008782	tetramer interface [polypeptide binding]; other site
1132507008783	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507008784	catalytic residue [active]
1132507008785	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1132507008786	lipoyl attachment site [posttranslational modification]; other site
1132507008787	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1132507008788	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1132507008789	oxidoreductase; Provisional; Region: PRK08013
1132507008790	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1132507008791	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1132507008792	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1132507008793	proline aminopeptidase P II; Provisional; Region: PRK10879
1132507008794	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1132507008795	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1132507008796	active site
1132507008797	hypothetical protein; Reviewed; Region: PRK01736
1132507008798	Z-ring-associated protein; Provisional; Region: PRK10972
1132507008799	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1132507008800	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1132507008801	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1132507008802	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1132507008803	ligand binding site [chemical binding]; other site
1132507008804	NAD binding site [chemical binding]; other site
1132507008805	tetramer interface [polypeptide binding]; other site
1132507008806	catalytic site [active]
1132507008807	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1132507008808	L-serine binding site [chemical binding]; other site
1132507008809	ACT domain interface; other site
1132507008810	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1132507008811	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1132507008812	active site
1132507008813	dimer interface [polypeptide binding]; other site
1132507008814	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1132507008815	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507008816	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1132507008817	putative dimerization interface [polypeptide binding]; other site
1132507008818	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1132507008819	oxidative stress defense protein; Provisional; Region: PRK11087
1132507008820	arginine exporter protein; Provisional; Region: PRK09304
1132507008821	mechanosensitive channel MscS; Provisional; Region: PRK10334
1132507008822	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1132507008823	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507008824	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1132507008825	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1132507008826	active site
1132507008827	intersubunit interface [polypeptide binding]; other site
1132507008828	zinc binding site [ion binding]; other site
1132507008829	Na+ binding site [ion binding]; other site
1132507008830	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1132507008831	Phosphoglycerate kinase; Region: PGK; pfam00162
1132507008832	substrate binding site [chemical binding]; other site
1132507008833	hinge regions; other site
1132507008834	ADP binding site [chemical binding]; other site
1132507008835	catalytic site [active]
1132507008836	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1132507008837	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1132507008838	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1132507008839	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1132507008840	trimer interface [polypeptide binding]; other site
1132507008841	putative Zn binding site [ion binding]; other site
1132507008842	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1132507008843	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1132507008844	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1132507008845	Walker A/P-loop; other site
1132507008846	ATP binding site [chemical binding]; other site
1132507008847	Q-loop/lid; other site
1132507008848	ABC transporter signature motif; other site
1132507008849	Walker B; other site
1132507008850	D-loop; other site
1132507008851	H-loop/switch region; other site
1132507008852	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1132507008853	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1132507008854	Walker A/P-loop; other site
1132507008855	ATP binding site [chemical binding]; other site
1132507008856	Q-loop/lid; other site
1132507008857	ABC transporter signature motif; other site
1132507008858	Walker B; other site
1132507008859	D-loop; other site
1132507008860	H-loop/switch region; other site
1132507008861	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507008862	transketolase; Reviewed; Region: PRK12753
1132507008863	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1132507008864	TPP-binding site [chemical binding]; other site
1132507008865	dimer interface [polypeptide binding]; other site
1132507008866	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1132507008867	PYR/PP interface [polypeptide binding]; other site
1132507008868	dimer interface [polypeptide binding]; other site
1132507008869	TPP binding site [chemical binding]; other site
1132507008870	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1132507008871	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1132507008872	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1132507008873	agmatinase; Region: agmatinase; TIGR01230
1132507008874	oligomer interface [polypeptide binding]; other site
1132507008875	putative active site [active]
1132507008876	Mn binding site [ion binding]; other site
1132507008877	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1132507008878	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1132507008879	dimer interface [polypeptide binding]; other site
1132507008880	active site
1132507008881	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1132507008882	catalytic residues [active]
1132507008883	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1132507008884	Virulence promoting factor; Region: YqgB; pfam11036
1132507008885	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1132507008886	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1132507008887	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1132507008888	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1132507008889	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1132507008890	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008891	putative substrate translocation pore; other site
1132507008892	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008893	hypothetical protein; Provisional; Region: PRK04860
1132507008894	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1132507008895	DNA-specific endonuclease I; Provisional; Region: PRK15137
1132507008896	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1132507008897	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1132507008898	RNA methyltransferase, RsmE family; Region: TIGR00046
1132507008899	glutathione synthetase; Provisional; Region: PRK05246
1132507008900	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1132507008901	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1132507008902	hypothetical protein; Validated; Region: PRK00228
1132507008903	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1132507008904	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1132507008905	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1132507008906	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1132507008907	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1132507008908	Walker A motif; other site
1132507008909	ATP binding site [chemical binding]; other site
1132507008910	Walker B motif; other site
1132507008911	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1132507008912	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1132507008913	catalytic residue [active]
1132507008914	YGGT family; Region: YGGT; pfam02325
1132507008915	YGGT family; Region: YGGT; pfam02325
1132507008916	hypothetical protein; Validated; Region: PRK05090
1132507008917	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1132507008918	active site
1132507008919	dimerization interface [polypeptide binding]; other site
1132507008920	HemN family oxidoreductase; Provisional; Region: PRK05660
1132507008921	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507008922	FeS/SAM binding site; other site
1132507008923	HemN C-terminal domain; Region: HemN_C; pfam06969
1132507008924	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
1132507008925	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
1132507008926	homodimer interface [polypeptide binding]; other site
1132507008927	active site
1132507008928	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507008929	hypothetical protein; Provisional; Region: PRK10626
1132507008930	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1132507008931	hypothetical protein; Provisional; Region: PRK11702
1132507008932	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1132507008933	adenine DNA glycosylase; Provisional; Region: PRK10880
1132507008934	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1132507008935	minor groove reading motif; other site
1132507008936	helix-hairpin-helix signature motif; other site
1132507008937	substrate binding pocket [chemical binding]; other site
1132507008938	active site
1132507008939	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1132507008940	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1132507008941	DNA binding and oxoG recognition site [nucleotide binding]
1132507008942	oxidative damage protection protein; Provisional; Region: PRK05408
1132507008943	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1132507008944	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1132507008945	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1132507008946	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1132507008947	catalytic residue [active]
1132507008948	nucleoside transporter; Region: 2A0110; TIGR00889
1132507008949	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
1132507008950	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1132507008951	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1132507008952	Protein of unknown function (DUF796); Region: DUF796; cl01226
1132507008953	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
1132507008954	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
1132507008955	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
1132507008956	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1132507008957	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507008958	DNA binding residues [nucleotide binding]
1132507008959	dimerization interface [polypeptide binding]; other site
1132507008960	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
1132507008961	Amino acid permease; Region: AA_permease_2; pfam13520
1132507008962	Protein of unknown function (DUF861); Region: Cupin_3; cl17594
1132507008963	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1132507008964	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1132507008965	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
1132507008966	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1132507008967	NAD(P) binding site [chemical binding]; other site
1132507008968	catalytic residues [active]
1132507008969	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
1132507008970	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1132507008971	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1132507008972	active site
1132507008973	catalytic site [active]
1132507008974	Zn binding site [ion binding]; other site
1132507008975	tetramer interface [polypeptide binding]; other site
1132507008976	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1132507008977	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1132507008978	active site
1132507008979	catalytic triad [active]
1132507008980	dimer interface [polypeptide binding]; other site
1132507008981	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507008982	D-galactonate transporter; Region: 2A0114; TIGR00893
1132507008983	putative substrate translocation pore; other site
1132507008984	mannonate dehydratase; Provisional; Region: PRK03906
1132507008985	mannonate dehydratase; Region: uxuA; TIGR00695
1132507008986	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1132507008987	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1132507008988	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1132507008989	Glucuronate isomerase; Region: UxaC; pfam02614
1132507008990	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1132507008991	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1132507008992	dimer interface [polypeptide binding]; other site
1132507008993	putative CheW interface [polypeptide binding]; other site
1132507008994	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1132507008995	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1132507008996	CHAP domain; Region: CHAP; pfam05257
1132507008997	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1132507008998	putative S-transferase; Provisional; Region: PRK11752
1132507008999	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1132507009000	C-terminal domain interface [polypeptide binding]; other site
1132507009001	GSH binding site (G-site) [chemical binding]; other site
1132507009002	dimer interface [polypeptide binding]; other site
1132507009003	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1132507009004	dimer interface [polypeptide binding]; other site
1132507009005	N-terminal domain interface [polypeptide binding]; other site
1132507009006	active site
1132507009007	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1132507009008	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
1132507009009	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1132507009010	putative ligand binding residues [chemical binding]; other site
1132507009011	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1132507009012	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
1132507009013	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1132507009014	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
1132507009015	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
1132507009016	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1132507009017	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1132507009018	putative substrate-binding site; other site
1132507009019	nickel binding site [ion binding]; other site
1132507009020	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1132507009021	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1132507009022	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
1132507009023	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1132507009024	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
1132507009025	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1132507009026	hydrogenase 2 small subunit; Provisional; Region: PRK10468
1132507009027	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1132507009028	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1132507009029	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
1132507009030	hypothetical protein; Provisional; Region: PRK05208
1132507009031	oxidoreductase; Provisional; Region: PRK07985
1132507009032	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1132507009033	NAD binding site [chemical binding]; other site
1132507009034	metal binding site [ion binding]; metal-binding site
1132507009035	active site
1132507009036	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1132507009037	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1132507009038	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1132507009039	cystathionine beta-lyase; Provisional; Region: PRK08114
1132507009040	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1132507009041	homodimer interface [polypeptide binding]; other site
1132507009042	substrate-cofactor binding pocket; other site
1132507009043	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507009044	catalytic residue [active]
1132507009045	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1132507009046	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1132507009047	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1132507009048	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1132507009049	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507009050	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507009051	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1132507009052	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1132507009053	dimer interface [polypeptide binding]; other site
1132507009054	active site
1132507009055	metal binding site [ion binding]; metal-binding site
1132507009056	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1132507009057	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1132507009058	transmembrane helices; other site
1132507009059	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1132507009060	nucleotide binding site/active site [active]
1132507009061	catalytic residue [active]
1132507009062	hypothetical protein; Provisional; Region: PRK01254
1132507009063	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1132507009064	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1132507009065	YARHG domain; Region: YARHG; pfam13308
1132507009066	FtsI repressor; Provisional; Region: PRK10883
1132507009067	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1132507009068	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1132507009069	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1132507009070	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1132507009071	putative acyl-acceptor binding pocket; other site
1132507009072	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
1132507009073	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1132507009074	CAP-like domain; other site
1132507009075	active site
1132507009076	primary dimer interface [polypeptide binding]; other site
1132507009077	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1132507009078	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1132507009079	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507009080	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1132507009081	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1132507009082	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1132507009083	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507009084	active site
1132507009085	phosphorylation site [posttranslational modification]
1132507009086	intermolecular recognition site; other site
1132507009087	dimerization interface [polypeptide binding]; other site
1132507009088	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507009089	DNA binding site [nucleotide binding]
1132507009090	sensor protein QseC; Provisional; Region: PRK10337
1132507009091	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1132507009092	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507009093	dimer interface [polypeptide binding]; other site
1132507009094	phosphorylation site [posttranslational modification]
1132507009095	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507009096	ATP binding site [chemical binding]; other site
1132507009097	Mg2+ binding site [ion binding]; other site
1132507009098	G-X-G motif; other site
1132507009099	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1132507009100	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1132507009101	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507009102	ATP binding site [chemical binding]; other site
1132507009103	Mg2+ binding site [ion binding]; other site
1132507009104	G-X-G motif; other site
1132507009105	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1132507009106	anchoring element; other site
1132507009107	dimer interface [polypeptide binding]; other site
1132507009108	ATP binding site [chemical binding]; other site
1132507009109	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1132507009110	active site
1132507009111	metal binding site [ion binding]; metal-binding site
1132507009112	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1132507009113	esterase YqiA; Provisional; Region: PRK11071
1132507009114	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1132507009115	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1132507009116	active site
1132507009117	metal binding site [ion binding]; metal-binding site
1132507009118	hexamer interface [polypeptide binding]; other site
1132507009119	putative dehydrogenase; Provisional; Region: PRK11039
1132507009120	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1132507009121	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1132507009122	dimer interface [polypeptide binding]; other site
1132507009123	ADP-ribose binding site [chemical binding]; other site
1132507009124	active site
1132507009125	nudix motif; other site
1132507009126	metal binding site [ion binding]; metal-binding site
1132507009127	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1132507009128	hypothetical protein; Provisional; Region: PRK11653
1132507009129	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1132507009130	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1132507009131	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1132507009132	putative active site [active]
1132507009133	metal binding site [ion binding]; metal-binding site
1132507009134	zinc transporter ZupT; Provisional; Region: PRK04201
1132507009135	ZIP Zinc transporter; Region: Zip; pfam02535
1132507009136	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
1132507009137	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1132507009138	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1132507009139	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1132507009140	catalytic residues [active]
1132507009141	hinge region; other site
1132507009142	alpha helical domain; other site
1132507009143	putative disulfide oxidoreductase; Provisional; Region: PRK04307
1132507009144	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1132507009145	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1132507009146	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1132507009147	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
1132507009148	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
1132507009149	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1132507009150	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1132507009151	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1132507009152	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1132507009153	putative ribose interaction site [chemical binding]; other site
1132507009154	putative ADP binding site [chemical binding]; other site
1132507009155	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1132507009156	active site
1132507009157	nucleotide binding site [chemical binding]; other site
1132507009158	HIGH motif; other site
1132507009159	KMSKS motif; other site
1132507009160	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1132507009161	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1132507009162	metal binding triad; other site
1132507009163	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1132507009164	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1132507009165	metal binding triad; other site
1132507009166	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1132507009167	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1132507009168	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1132507009169	putative active site [active]
1132507009170	putative metal binding residues [ion binding]; other site
1132507009171	signature motif; other site
1132507009172	putative triphosphate binding site [ion binding]; other site
1132507009173	CHAD domain; Region: CHAD; pfam05235
1132507009174	SH3 domain-containing protein; Provisional; Region: PRK10884
1132507009175	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1132507009176	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1132507009177	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1132507009178	active site
1132507009179	NTP binding site [chemical binding]; other site
1132507009180	metal binding triad [ion binding]; metal-binding site
1132507009181	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1132507009182	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1132507009183	Zn2+ binding site [ion binding]; other site
1132507009184	Mg2+ binding site [ion binding]; other site
1132507009185	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1132507009186	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1132507009187	homooctamer interface [polypeptide binding]; other site
1132507009188	active site
1132507009189	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1132507009190	UGMP family protein; Validated; Region: PRK09604
1132507009191	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1132507009192	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1132507009193	DNA primase; Validated; Region: dnaG; PRK05667
1132507009194	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1132507009195	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1132507009196	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1132507009197	active site
1132507009198	metal binding site [ion binding]; metal-binding site
1132507009199	interdomain interaction site; other site
1132507009200	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1132507009201	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1132507009202	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1132507009203	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1132507009204	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1132507009205	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1132507009206	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1132507009207	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1132507009208	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1132507009209	DNA binding residues [nucleotide binding]
1132507009210	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1132507009211	active site
1132507009212	SUMO-1 interface [polypeptide binding]; other site
1132507009213	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1132507009214	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1132507009215	FAD binding pocket [chemical binding]; other site
1132507009216	FAD binding motif [chemical binding]; other site
1132507009217	phosphate binding motif [ion binding]; other site
1132507009218	NAD binding pocket [chemical binding]; other site
1132507009219	Predicted transcriptional regulators [Transcription]; Region: COG1695
1132507009220	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1132507009221	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1132507009222	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507009223	dimerization interface [polypeptide binding]; other site
1132507009224	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1132507009225	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1132507009226	dimer interface [polypeptide binding]; other site
1132507009227	putative CheW interface [polypeptide binding]; other site
1132507009228	PAS fold; Region: PAS_3; pfam08447
1132507009229	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1132507009230	putative active site [active]
1132507009231	heme pocket [chemical binding]; other site
1132507009232	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1132507009233	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1132507009234	dimer interface [polypeptide binding]; other site
1132507009235	putative CheW interface [polypeptide binding]; other site
1132507009236	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
1132507009237	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1132507009238	inhibitor-cofactor binding pocket; inhibition site
1132507009239	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507009240	catalytic residue [active]
1132507009241	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1132507009242	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507009243	S-adenosylmethionine binding site [chemical binding]; other site
1132507009244	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1132507009245	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1132507009246	putative active site [active]
1132507009247	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1132507009248	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1132507009249	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1132507009250	serine/threonine transporter SstT; Provisional; Region: PRK13628
1132507009251	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1132507009252	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1132507009253	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1132507009254	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1132507009255	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1132507009256	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1132507009257	Predicted membrane protein [Function unknown]; Region: COG5393
1132507009258	YqjK-like protein; Region: YqjK; pfam13997
1132507009259	Predicted membrane protein [Function unknown]; Region: COG2259
1132507009260	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1132507009261	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1132507009262	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1132507009263	putative dimer interface [polypeptide binding]; other site
1132507009264	N-terminal domain interface [polypeptide binding]; other site
1132507009265	putative substrate binding pocket (H-site) [chemical binding]; other site
1132507009266	Predicted membrane protein [Function unknown]; Region: COG3152
1132507009267	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507009268	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1132507009269	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507009270	dimerization interface [polypeptide binding]; other site
1132507009271	Pirin-related protein [General function prediction only]; Region: COG1741
1132507009272	Pirin; Region: Pirin; pfam02678
1132507009273	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1132507009274	L-serine dehydratase TdcG; Provisional; Region: PRK15040
1132507009275	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1132507009276	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1132507009277	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1132507009278	Pyruvate formate lyase 1; Region: PFL1; cd01678
1132507009279	coenzyme A binding site [chemical binding]; other site
1132507009280	active site
1132507009281	catalytic residues [active]
1132507009282	glycine loop; other site
1132507009283	propionate/acetate kinase; Provisional; Region: PRK12379
1132507009284	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
1132507009285	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1132507009286	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1132507009287	tetramer interface [polypeptide binding]; other site
1132507009288	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507009289	catalytic residue [active]
1132507009290	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1132507009291	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507009292	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1132507009293	putative substrate binding pocket [chemical binding]; other site
1132507009294	putative dimerization interface [polypeptide binding]; other site
1132507009295	glycerate kinase I; Provisional; Region: PRK10342
1132507009296	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1132507009297	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1132507009298	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1132507009299	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1132507009300	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1132507009301	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1132507009302	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1132507009303	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1132507009304	substrate binding site [chemical binding]; other site
1132507009305	ATP binding site [chemical binding]; other site
1132507009306	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1132507009307	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1132507009308	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507009309	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1132507009310	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1132507009311	intersubunit interface [polypeptide binding]; other site
1132507009312	active site
1132507009313	zinc binding site [ion binding]; other site
1132507009314	Na+ binding site [ion binding]; other site
1132507009315	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1132507009316	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1132507009317	putative substrate binding site [chemical binding]; other site
1132507009318	putative ATP binding site [chemical binding]; other site
1132507009319	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1132507009320	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1132507009321	active site
1132507009322	P-loop; other site
1132507009323	phosphorylation site [posttranslational modification]
1132507009324	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1132507009325	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1132507009326	active site
1132507009327	phosphorylation site [posttranslational modification]
1132507009328	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1132507009329	dimerization domain swap beta strand [polypeptide binding]; other site
1132507009330	regulatory protein interface [polypeptide binding]; other site
1132507009331	active site
1132507009332	regulatory phosphorylation site [posttranslational modification]; other site
1132507009333	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1132507009334	active site
1132507009335	phosphorylation site [posttranslational modification]
1132507009336	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1132507009337	active site
1132507009338	P-loop; other site
1132507009339	phosphorylation site [posttranslational modification]
1132507009340	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1132507009341	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1132507009342	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1132507009343	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1132507009344	putative NAD(P) binding site [chemical binding]; other site
1132507009345	catalytic Zn binding site [ion binding]; other site
1132507009346	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1132507009347	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1132507009348	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507009349	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1132507009350	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1132507009351	putative SAM binding site [chemical binding]; other site
1132507009352	putative homodimer interface [polypeptide binding]; other site
1132507009353	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1132507009354	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
1132507009355	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1132507009356	putative ligand binding site [chemical binding]; other site
1132507009357	TIGR00252 family protein; Region: TIGR00252
1132507009358	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1132507009359	dimer interface [polypeptide binding]; other site
1132507009360	active site
1132507009361	outer membrane lipoprotein; Provisional; Region: PRK11023
1132507009362	BON domain; Region: BON; pfam04972
1132507009363	BON domain; Region: BON; pfam04972
1132507009364	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1132507009365	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1132507009366	NAD binding site [chemical binding]; other site
1132507009367	active site
1132507009368	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1132507009369	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1132507009370	proposed catalytic triad [active]
1132507009371	conserved cys residue [active]
1132507009372	hypothetical protein; Provisional; Region: PRK03467
1132507009373	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1132507009374	GIY-YIG motif/motif A; other site
1132507009375	putative active site [active]
1132507009376	putative metal binding site [ion binding]; other site
1132507009377	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1132507009378	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507009379	Coenzyme A binding pocket [chemical binding]; other site
1132507009380	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1132507009381	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1132507009382	Peptidase family U32; Region: Peptidase_U32; pfam01136
1132507009383	putative protease; Provisional; Region: PRK15447
1132507009384	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1132507009385	hypothetical protein; Provisional; Region: PRK10508
1132507009386	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1132507009387	tryptophan permease; Provisional; Region: PRK10483
1132507009388	aromatic amino acid transport protein; Region: araaP; TIGR00837
1132507009389	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1132507009390	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1132507009391	ATP binding site [chemical binding]; other site
1132507009392	Mg++ binding site [ion binding]; other site
1132507009393	motif III; other site
1132507009394	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507009395	nucleotide binding region [chemical binding]; other site
1132507009396	ATP-binding site [chemical binding]; other site
1132507009397	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1132507009398	putative RNA binding site [nucleotide binding]; other site
1132507009399	lipoprotein NlpI; Provisional; Region: PRK11189
1132507009400	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1132507009401	binding surface
1132507009402	TPR motif; other site
1132507009403	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1132507009404	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1132507009405	RNase E interface [polypeptide binding]; other site
1132507009406	trimer interface [polypeptide binding]; other site
1132507009407	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1132507009408	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1132507009409	RNase E interface [polypeptide binding]; other site
1132507009410	trimer interface [polypeptide binding]; other site
1132507009411	active site
1132507009412	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1132507009413	putative nucleic acid binding region [nucleotide binding]; other site
1132507009414	G-X-X-G motif; other site
1132507009415	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1132507009416	RNA binding site [nucleotide binding]; other site
1132507009417	domain interface; other site
1132507009418	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1132507009419	16S/18S rRNA binding site [nucleotide binding]; other site
1132507009420	S13e-L30e interaction site [polypeptide binding]; other site
1132507009421	25S rRNA binding site [nucleotide binding]; other site
1132507009422	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1132507009423	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1132507009424	RNA binding site [nucleotide binding]; other site
1132507009425	active site
1132507009426	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1132507009427	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1132507009428	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1132507009429	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1132507009430	translation initiation factor IF-2; Region: IF-2; TIGR00487
1132507009431	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1132507009432	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1132507009433	G1 box; other site
1132507009434	putative GEF interaction site [polypeptide binding]; other site
1132507009435	GTP/Mg2+ binding site [chemical binding]; other site
1132507009436	Switch I region; other site
1132507009437	G2 box; other site
1132507009438	G3 box; other site
1132507009439	Switch II region; other site
1132507009440	G4 box; other site
1132507009441	G5 box; other site
1132507009442	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1132507009443	Translation-initiation factor 2; Region: IF-2; pfam11987
1132507009444	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1132507009445	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1132507009446	NusA N-terminal domain; Region: NusA_N; pfam08529
1132507009447	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1132507009448	RNA binding site [nucleotide binding]; other site
1132507009449	homodimer interface [polypeptide binding]; other site
1132507009450	NusA-like KH domain; Region: KH_5; pfam13184
1132507009451	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1132507009452	G-X-X-G motif; other site
1132507009453	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1132507009454	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1132507009455	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1132507009456	hypothetical protein; Provisional; Region: PRK14641
1132507009457	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1132507009458	putative oligomer interface [polypeptide binding]; other site
1132507009459	putative RNA binding site [nucleotide binding]; other site
1132507009460	argininosuccinate synthase; Validated; Region: PRK05370
1132507009461	argininosuccinate synthase; Provisional; Region: PRK13820
1132507009462	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1132507009463	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1132507009464	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1132507009465	active site
1132507009466	substrate binding site [chemical binding]; other site
1132507009467	metal binding site [ion binding]; metal-binding site
1132507009468	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1132507009469	dihydropteroate synthase; Region: DHPS; TIGR01496
1132507009470	substrate binding pocket [chemical binding]; other site
1132507009471	dimer interface [polypeptide binding]; other site
1132507009472	inhibitor binding site; inhibition site
1132507009473	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1132507009474	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507009475	Walker A motif; other site
1132507009476	ATP binding site [chemical binding]; other site
1132507009477	Walker B motif; other site
1132507009478	arginine finger; other site
1132507009479	Peptidase family M41; Region: Peptidase_M41; pfam01434
1132507009480	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1132507009481	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507009482	S-adenosylmethionine binding site [chemical binding]; other site
1132507009483	RNA-binding protein YhbY; Provisional; Region: PRK10343
1132507009484	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1132507009485	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1132507009486	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1132507009487	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1132507009488	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1132507009489	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1132507009490	GTP1/OBG; Region: GTP1_OBG; pfam01018
1132507009491	Obg GTPase; Region: Obg; cd01898
1132507009492	G1 box; other site
1132507009493	GTP/Mg2+ binding site [chemical binding]; other site
1132507009494	Switch I region; other site
1132507009495	G2 box; other site
1132507009496	G3 box; other site
1132507009497	Switch II region; other site
1132507009498	G4 box; other site
1132507009499	G5 box; other site
1132507009500	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1132507009501	EamA-like transporter family; Region: EamA; pfam00892
1132507009502	EamA-like transporter family; Region: EamA; pfam00892
1132507009503	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1132507009504	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1132507009505	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1132507009506	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1132507009507	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1132507009508	substrate binding pocket [chemical binding]; other site
1132507009509	chain length determination region; other site
1132507009510	substrate-Mg2+ binding site; other site
1132507009511	catalytic residues [active]
1132507009512	aspartate-rich region 1; other site
1132507009513	active site lid residues [active]
1132507009514	aspartate-rich region 2; other site
1132507009515	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1132507009516	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1132507009517	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1132507009518	hinge; other site
1132507009519	active site
1132507009520	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1132507009521	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1132507009522	anti sigma factor interaction site; other site
1132507009523	regulatory phosphorylation site [posttranslational modification]; other site
1132507009524	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1132507009525	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1132507009526	mce related protein; Region: MCE; pfam02470
1132507009527	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1132507009528	conserved hypothetical integral membrane protein; Region: TIGR00056
1132507009529	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1132507009530	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1132507009531	Walker A/P-loop; other site
1132507009532	ATP binding site [chemical binding]; other site
1132507009533	Q-loop/lid; other site
1132507009534	ABC transporter signature motif; other site
1132507009535	Walker B; other site
1132507009536	D-loop; other site
1132507009537	H-loop/switch region; other site
1132507009538	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1132507009539	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1132507009540	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1132507009541	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1132507009542	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1132507009543	putative active site [active]
1132507009544	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1132507009545	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1132507009546	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1132507009547	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1132507009548	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1132507009549	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1132507009550	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1132507009551	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1132507009552	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1132507009553	Walker A/P-loop; other site
1132507009554	ATP binding site [chemical binding]; other site
1132507009555	Q-loop/lid; other site
1132507009556	ABC transporter signature motif; other site
1132507009557	Walker B; other site
1132507009558	D-loop; other site
1132507009559	H-loop/switch region; other site
1132507009560	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1132507009561	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1132507009562	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1132507009563	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1132507009564	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1132507009565	30S subunit binding site; other site
1132507009566	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1132507009567	active site
1132507009568	phosphorylation site [posttranslational modification]
1132507009569	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
1132507009570	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1132507009571	dimerization domain swap beta strand [polypeptide binding]; other site
1132507009572	regulatory protein interface [polypeptide binding]; other site
1132507009573	active site
1132507009574	regulatory phosphorylation site [posttranslational modification]; other site
1132507009575	hypothetical protein; Provisional; Region: PRK10345
1132507009576	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1132507009577	Transglycosylase; Region: Transgly; cl17702
1132507009578	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1132507009579	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1132507009580	conserved cys residue [active]
1132507009581	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1132507009582	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1132507009583	putative active site [active]
1132507009584	heme pocket [chemical binding]; other site
1132507009585	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507009586	dimer interface [polypeptide binding]; other site
1132507009587	phosphorylation site [posttranslational modification]
1132507009588	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507009589	ATP binding site [chemical binding]; other site
1132507009590	Mg2+ binding site [ion binding]; other site
1132507009591	G-X-G motif; other site
1132507009592	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507009593	active site
1132507009594	phosphorylation site [posttranslational modification]
1132507009595	intermolecular recognition site; other site
1132507009596	dimerization interface [polypeptide binding]; other site
1132507009597	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1132507009598	putative binding surface; other site
1132507009599	active site
1132507009600	radical SAM protein, TIGR01212 family; Region: TIGR01212
1132507009601	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507009602	FeS/SAM binding site; other site
1132507009603	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1132507009604	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1132507009605	active site
1132507009606	dimer interface [polypeptide binding]; other site
1132507009607	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1132507009608	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1132507009609	active site
1132507009610	FMN binding site [chemical binding]; other site
1132507009611	substrate binding site [chemical binding]; other site
1132507009612	3Fe-4S cluster binding site [ion binding]; other site
1132507009613	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1132507009614	domain interface; other site
1132507009615	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1132507009616	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1132507009617	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507009618	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1132507009619	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1132507009620	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1132507009621	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1132507009622	Na binding site [ion binding]; other site
1132507009623	putative substrate binding site [chemical binding]; other site
1132507009624	cytosine deaminase; Provisional; Region: PRK09230
1132507009625	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1132507009626	active site
1132507009627	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1132507009628	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1132507009629	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1132507009630	nucleotide binding site [chemical binding]; other site
1132507009631	Putative N-acetylmannosamine-6-phosphate epimerase; Region: NanE; pfam04131
1132507009632	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1132507009633	putative sialic acid transporter; Provisional; Region: PRK03893
1132507009634	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507009635	putative substrate translocation pore; other site
1132507009636	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1132507009637	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1132507009638	inhibitor site; inhibition site
1132507009639	active site
1132507009640	dimer interface [polypeptide binding]; other site
1132507009641	catalytic residue [active]
1132507009642	transcriptional regulator NanR; Provisional; Region: PRK03837
1132507009643	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507009644	DNA-binding site [nucleotide binding]; DNA binding site
1132507009645	FCD domain; Region: FCD; pfam07729
1132507009646	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
1132507009647	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1132507009648	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1132507009649	C-terminal domain interface [polypeptide binding]; other site
1132507009650	putative GSH binding site (G-site) [chemical binding]; other site
1132507009651	dimer interface [polypeptide binding]; other site
1132507009652	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1132507009653	dimer interface [polypeptide binding]; other site
1132507009654	N-terminal domain interface [polypeptide binding]; other site
1132507009655	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1132507009656	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1132507009657	23S rRNA interface [nucleotide binding]; other site
1132507009658	L3 interface [polypeptide binding]; other site
1132507009659	Predicted ATPase [General function prediction only]; Region: COG1485
1132507009660	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1132507009661	hypothetical protein; Provisional; Region: PRK11677
1132507009662	serine endoprotease; Provisional; Region: PRK10139
1132507009663	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1132507009664	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1132507009665	protein binding site [polypeptide binding]; other site
1132507009666	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1132507009667	serine endoprotease; Provisional; Region: PRK10898
1132507009668	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1132507009669	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1132507009670	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1132507009671	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1132507009672	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1132507009673	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1132507009674	active site
1132507009675	catalytic residues [active]
1132507009676	metal binding site [ion binding]; metal-binding site
1132507009677	homodimer binding site [polypeptide binding]; other site
1132507009678	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1132507009679	carboxyltransferase (CT) interaction site; other site
1132507009680	biotinylation site [posttranslational modification]; other site
1132507009681	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1132507009682	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
1132507009683	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
1132507009684	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1132507009685	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1132507009686	transmembrane helices; other site
1132507009687	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1132507009688	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507009689	DNA-binding site [nucleotide binding]; DNA binding site
1132507009690	FCD domain; Region: FCD; pfam07729
1132507009691	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1132507009692	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507009693	DNA-binding site [nucleotide binding]; DNA binding site
1132507009694	malate dehydrogenase; Provisional; Region: PRK05086
1132507009695	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1132507009696	NAD binding site [chemical binding]; other site
1132507009697	dimerization interface [polypeptide binding]; other site
1132507009698	Substrate binding site [chemical binding]; other site
1132507009699	arginine repressor; Provisional; Region: PRK05066
1132507009700	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1132507009701	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1132507009702	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1132507009703	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1132507009704	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1132507009705	RNAase interaction site [polypeptide binding]; other site
1132507009706	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1132507009707	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1132507009708	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1132507009709	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1132507009710	HlyD family secretion protein; Region: HlyD_3; pfam13437
1132507009711	efflux system membrane protein; Provisional; Region: PRK11594
1132507009712	transcriptional regulator; Provisional; Region: PRK10632
1132507009713	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507009714	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1132507009715	putative effector binding pocket; other site
1132507009716	dimerization interface [polypeptide binding]; other site
1132507009717	protease TldD; Provisional; Region: tldD; PRK10735
1132507009718	hypothetical protein; Provisional; Region: PRK10899
1132507009719	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1132507009720	ribonuclease G; Provisional; Region: PRK11712
1132507009721	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1132507009722	homodimer interface [polypeptide binding]; other site
1132507009723	oligonucleotide binding site [chemical binding]; other site
1132507009724	Maf-like protein; Region: Maf; pfam02545
1132507009725	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1132507009726	active site
1132507009727	dimer interface [polypeptide binding]; other site
1132507009728	rod shape-determining protein MreD; Provisional; Region: PRK11060
1132507009729	rod shape-determining protein MreC; Region: mreC; TIGR00219
1132507009730	rod shape-determining protein MreC; Region: MreC; pfam04085
1132507009731	rod shape-determining protein MreB; Provisional; Region: PRK13927
1132507009732	MreB and similar proteins; Region: MreB_like; cd10225
1132507009733	nucleotide binding site [chemical binding]; other site
1132507009734	Mg binding site [ion binding]; other site
1132507009735	putative protofilament interaction site [polypeptide binding]; other site
1132507009736	RodZ interaction site [polypeptide binding]; other site
1132507009737	regulatory protein CsrD; Provisional; Region: PRK11059
1132507009738	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507009739	metal binding site [ion binding]; metal-binding site
1132507009740	active site
1132507009741	I-site; other site
1132507009742	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507009743	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1132507009744	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1132507009745	NADP binding site [chemical binding]; other site
1132507009746	dimer interface [polypeptide binding]; other site
1132507009747	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1132507009748	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1132507009749	Moco binding site; other site
1132507009750	metal coordination site [ion binding]; other site
1132507009751	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1132507009752	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1132507009753	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1132507009754	carboxyltransferase (CT) interaction site; other site
1132507009755	biotinylation site [posttranslational modification]; other site
1132507009756	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1132507009757	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1132507009758	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1132507009759	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1132507009760	hypothetical protein; Provisional; Region: PRK10633
1132507009761	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1132507009762	Na binding site [ion binding]; other site
1132507009763	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
1132507009764	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1132507009765	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
1132507009766	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1132507009767	FMN binding site [chemical binding]; other site
1132507009768	active site
1132507009769	catalytic residues [active]
1132507009770	substrate binding site [chemical binding]; other site
1132507009771	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1132507009772	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1132507009773	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1132507009774	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507009775	DNA methylase; Region: N6_N4_Mtase; pfam01555
1132507009776	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
1132507009777	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1132507009778	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1132507009779	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1132507009780	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507009781	metal binding site [ion binding]; metal-binding site
1132507009782	active site
1132507009783	I-site; other site
1132507009784	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507009785	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1132507009786	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1132507009787	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1132507009788	potassium transporter; Provisional; Region: PRK10750
1132507009789	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1132507009790	hypothetical protein; Provisional; Region: PRK11568
1132507009791	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1132507009792	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1132507009793	proline dipeptidase; Provisional; Region: PRK13607
1132507009794	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1132507009795	active site
1132507009796	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1132507009797	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1132507009798	substrate binding site [chemical binding]; other site
1132507009799	oxyanion hole (OAH) forming residues; other site
1132507009800	trimer interface [polypeptide binding]; other site
1132507009801	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1132507009802	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1132507009803	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1132507009804	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1132507009805	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1132507009806	dimer interface [polypeptide binding]; other site
1132507009807	active site
1132507009808	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1132507009809	FMN reductase; Validated; Region: fre; PRK08051
1132507009810	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1132507009811	FAD binding pocket [chemical binding]; other site
1132507009812	FAD binding motif [chemical binding]; other site
1132507009813	phosphate binding motif [ion binding]; other site
1132507009814	beta-alpha-beta structure motif; other site
1132507009815	NAD binding pocket [chemical binding]; other site
1132507009816	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1132507009817	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1132507009818	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1132507009819	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
1132507009820	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1132507009821	active site
1132507009822	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1132507009823	sec-independent translocase; Provisional; Region: PRK01770
1132507009824	sec-independent translocase; Provisional; Region: tatB; PRK00404
1132507009825	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1132507009826	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1132507009827	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1132507009828	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1132507009829	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1132507009830	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1132507009831	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507009832	S-adenosylmethionine binding site [chemical binding]; other site
1132507009833	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
1132507009834	DNA recombination protein RmuC; Provisional; Region: PRK10361
1132507009835	RmuC family; Region: RmuC; pfam02646
1132507009836	uridine phosphorylase; Provisional; Region: PRK11178
1132507009837	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
1132507009838	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1132507009839	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1132507009840	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507009841	FeS/SAM binding site; other site
1132507009842	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1132507009843	SEC-C motif; Region: SEC-C; pfam02810
1132507009844	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1132507009845	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1132507009846	THF binding site; other site
1132507009847	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1132507009848	substrate binding site [chemical binding]; other site
1132507009849	THF binding site; other site
1132507009850	zinc-binding site [ion binding]; other site
1132507009851	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1132507009852	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507009853	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1132507009854	putative dimerization interface [polypeptide binding]; other site
1132507009855	putative hydrolase; Provisional; Region: PRK10976
1132507009856	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507009857	active site
1132507009858	motif I; other site
1132507009859	motif II; other site
1132507009860	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507009861	lysophospholipase L2; Provisional; Region: PRK10749
1132507009862	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1132507009863	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1132507009864	threonine efflux system; Provisional; Region: PRK10229
1132507009865	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1132507009866	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507009867	ATP binding site [chemical binding]; other site
1132507009868	putative Mg++ binding site [ion binding]; other site
1132507009869	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507009870	nucleotide binding region [chemical binding]; other site
1132507009871	ATP-binding site [chemical binding]; other site
1132507009872	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1132507009873	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1132507009874	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1132507009875	dimerization interface [polypeptide binding]; other site
1132507009876	substrate binding site [chemical binding]; other site
1132507009877	active site
1132507009878	calcium binding site [ion binding]; other site
1132507009879	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1132507009880	CoenzymeA binding site [chemical binding]; other site
1132507009881	subunit interaction site [polypeptide binding]; other site
1132507009882	PHB binding site; other site
1132507009883	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1132507009884	EamA-like transporter family; Region: EamA; cl17759
1132507009885	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
1132507009886	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1132507009887	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1132507009888	Cl binding site [ion binding]; other site
1132507009889	oligomer interface [polypeptide binding]; other site
1132507009890	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1132507009891	Part of AAA domain; Region: AAA_19; pfam13245
1132507009892	Family description; Region: UvrD_C_2; pfam13538
1132507009893	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1132507009894	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507009895	motif II; other site
1132507009896	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1132507009897	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1132507009898	active site
1132507009899	Int/Topo IB signature motif; other site
1132507009900	hypothetical protein; Provisional; Region: PRK10963
1132507009901	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1132507009902	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1132507009903	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1132507009904	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1132507009905	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
1132507009906	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1132507009907	putative iron binding site [ion binding]; other site
1132507009908	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1132507009909	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1132507009910	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1132507009911	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1132507009912	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1132507009913	active site
1132507009914	domain interfaces; other site
1132507009915	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1132507009916	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1132507009917	active site
1132507009918	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1132507009919	HemX; Region: HemX; pfam04375
1132507009920	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1132507009921	HemY protein N-terminus; Region: HemY_N; pfam07219
1132507009922	putative transport protein YifK; Provisional; Region: PRK10746
1132507009923	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1132507009924	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1132507009925	putative common antigen polymerase; Provisional; Region: PRK02975
1132507009926	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1132507009927	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1132507009928	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1132507009929	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1132507009930	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1132507009931	inhibitor-cofactor binding pocket; inhibition site
1132507009932	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507009933	catalytic residue [active]
1132507009934	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
1132507009935	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1132507009936	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1132507009937	substrate binding site; other site
1132507009938	tetramer interface; other site
1132507009939	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
1132507009940	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1132507009941	NAD binding site [chemical binding]; other site
1132507009942	substrate binding site [chemical binding]; other site
1132507009943	homodimer interface [polypeptide binding]; other site
1132507009944	active site
1132507009945	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1132507009946	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1132507009947	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1132507009948	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
1132507009949	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1132507009950	homodimer interface [polypeptide binding]; other site
1132507009951	active site
1132507009952	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1132507009953	Chain length determinant protein; Region: Wzz; pfam02706
1132507009954	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1132507009955	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1132507009956	Mg++ binding site [ion binding]; other site
1132507009957	putative catalytic motif [active]
1132507009958	substrate binding site [chemical binding]; other site
1132507009959	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1132507009960	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1132507009961	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1132507009962	RNA binding site [nucleotide binding]; other site
1132507009963	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1132507009964	multimer interface [polypeptide binding]; other site
1132507009965	Walker A motif; other site
1132507009966	ATP binding site [chemical binding]; other site
1132507009967	Walker B motif; other site
1132507009968	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1132507009969	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1132507009970	catalytic residues [active]
1132507009971	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1132507009972	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1132507009973	ATP binding site [chemical binding]; other site
1132507009974	Mg++ binding site [ion binding]; other site
1132507009975	motif III; other site
1132507009976	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507009977	nucleotide binding region [chemical binding]; other site
1132507009978	ATP-binding site [chemical binding]; other site
1132507009979	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1132507009980	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1132507009981	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1132507009982	Part of AAA domain; Region: AAA_19; pfam13245
1132507009983	Family description; Region: UvrD_C_2; pfam13538
1132507009984	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1132507009985	uridine phosphorylase; Provisional; Region: PRK11178
1132507009986	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1132507009987	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1132507009988	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1132507009989	ketol-acid reductoisomerase; Validated; Region: PRK05225
1132507009990	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1132507009991	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1132507009992	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1132507009993	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507009994	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1132507009995	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1132507009996	putative dimerization interface [polypeptide binding]; other site
1132507009997	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
1132507009998	Phage-related protein [Function unknown]; Region: COG4679
1132507009999	threonine dehydratase; Reviewed; Region: PRK09224
1132507010000	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1132507010001	tetramer interface [polypeptide binding]; other site
1132507010002	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507010003	catalytic residue [active]
1132507010004	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1132507010005	putative Ile/Val binding site [chemical binding]; other site
1132507010006	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1132507010007	putative Ile/Val binding site [chemical binding]; other site
1132507010008	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1132507010009	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1132507010010	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1132507010011	homodimer interface [polypeptide binding]; other site
1132507010012	substrate-cofactor binding pocket; other site
1132507010013	catalytic residue [active]
1132507010014	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1132507010015	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1132507010016	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1132507010017	PYR/PP interface [polypeptide binding]; other site
1132507010018	dimer interface [polypeptide binding]; other site
1132507010019	TPP binding site [chemical binding]; other site
1132507010020	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1132507010021	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1132507010022	TPP-binding site [chemical binding]; other site
1132507010023	dimer interface [polypeptide binding]; other site
1132507010024	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1132507010025	integrase; Provisional; Region: int; PHA02601
1132507010026	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1132507010027	active site
1132507010028	DNA binding site [nucleotide binding]
1132507010029	Int/Topo IB signature motif; other site
1132507010030	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
1132507010031	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1132507010032	DksA-like zinc finger domain containing protein; Region: PHA00080
1132507010033	DNA adenine methylase (dam); Region: dam; TIGR00571
1132507010034	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1132507010035	The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p; Region: HIRAN; smart00910
1132507010036	portal vertex protein; Provisional; Region: Q; PHA02536
1132507010037	Phage portal protein; Region: Phage_portal; pfam04860
1132507010038	terminase ATPase subunit; Provisional; Region: P; PHA02535
1132507010039	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1132507010040	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
1132507010041	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
1132507010042	capsid protein; Provisional; Region: N; PHA02538
1132507010043	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1132507010044	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1132507010045	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1132507010046	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
1132507010047	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1132507010048	catalytic residues [active]
1132507010049	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1132507010050	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1132507010051	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1132507010052	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1132507010053	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1132507010054	baseplate wedge subunit; Provisional; Region: W; PHA02516
1132507010055	baseplate assembly protein; Provisional; Region: J; PHA02568
1132507010056	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1132507010057	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1132507010058	Phage Tail Collar Domain; Region: Collar; pfam07484
1132507010059	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1132507010060	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1132507010061	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1132507010062	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1132507010063	catalytic residues [active]
1132507010064	catalytic nucleophile [active]
1132507010065	Presynaptic Site I dimer interface [polypeptide binding]; other site
1132507010066	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1132507010067	Synaptic Flat tetramer interface [polypeptide binding]; other site
1132507010068	Synaptic Site I dimer interface [polypeptide binding]; other site
1132507010069	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1132507010070	DNA-binding interface [nucleotide binding]; DNA binding site
1132507010071	major tail sheath protein; Provisional; Region: FI; PHA02560
1132507010072	major tail tube protein; Provisional; Region: FII; PHA02600
1132507010073	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1132507010074	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1132507010075	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1132507010076	Phage protein U [General function prediction only]; Region: COG3499
1132507010077	tail protein; Provisional; Region: D; PHA02561
1132507010078	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1132507010079	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1132507010080	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1132507010081	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507010082	Walker A motif; other site
1132507010083	ATP binding site [chemical binding]; other site
1132507010084	Walker B motif; other site
1132507010085	arginine finger; other site
1132507010086	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1132507010087	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507010088	hypothetical protein; Provisional; Region: PRK11027
1132507010089	transcriptional regulator HdfR; Provisional; Region: PRK03601
1132507010090	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507010091	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1132507010092	dimerization interface [polypeptide binding]; other site
1132507010093	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1132507010094	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1132507010095	purine monophosphate binding site [chemical binding]; other site
1132507010096	dimer interface [polypeptide binding]; other site
1132507010097	putative catalytic residues [active]
1132507010098	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1132507010099	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1132507010100	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1132507010101	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1132507010102	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1132507010103	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
1132507010104	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507010105	active site
1132507010106	phosphorylation site [posttranslational modification]
1132507010107	intermolecular recognition site; other site
1132507010108	dimerization interface [polypeptide binding]; other site
1132507010109	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507010110	Walker A motif; other site
1132507010111	ATP binding site [chemical binding]; other site
1132507010112	Walker B motif; other site
1132507010113	arginine finger; other site
1132507010114	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1132507010115	sensor protein ZraS; Provisional; Region: PRK10364
1132507010116	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507010117	dimer interface [polypeptide binding]; other site
1132507010118	phosphorylation site [posttranslational modification]
1132507010119	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507010120	ATP binding site [chemical binding]; other site
1132507010121	Mg2+ binding site [ion binding]; other site
1132507010122	G-X-G motif; other site
1132507010123	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1132507010124	dimer interface [polypeptide binding]; other site
1132507010125	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1132507010126	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1132507010127	IHF dimer interface [polypeptide binding]; other site
1132507010128	IHF - DNA interface [nucleotide binding]; other site
1132507010129	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1132507010130	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1132507010131	Active_site [active]
1132507010132	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1132507010133	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1132507010134	substrate binding site [chemical binding]; other site
1132507010135	active site
1132507010136	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1132507010137	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1132507010138	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1132507010139	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1132507010140	putative NADH binding site [chemical binding]; other site
1132507010141	putative active site [active]
1132507010142	nudix motif; other site
1132507010143	putative metal binding site [ion binding]; other site
1132507010144	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
1132507010145	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1132507010146	ThiC-associated domain; Region: ThiC-associated; pfam13667
1132507010147	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1132507010148	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1132507010149	thiamine phosphate binding site [chemical binding]; other site
1132507010150	active site
1132507010151	pyrophosphate binding site [ion binding]; other site
1132507010152	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1132507010153	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1132507010154	ATP binding site [chemical binding]; other site
1132507010155	substrate interface [chemical binding]; other site
1132507010156	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1132507010157	thiS-thiF/thiG interaction site; other site
1132507010158	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1132507010159	ThiS interaction site; other site
1132507010160	putative active site [active]
1132507010161	tetramer interface [polypeptide binding]; other site
1132507010162	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1132507010163	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507010164	FeS/SAM binding site; other site
1132507010165	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1132507010166	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1132507010167	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1132507010168	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1132507010169	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1132507010170	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1132507010171	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1132507010172	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1132507010173	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1132507010174	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1132507010175	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1132507010176	DNA binding site [nucleotide binding]
1132507010177	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1132507010178	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1132507010179	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1132507010180	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1132507010181	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1132507010182	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1132507010183	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1132507010184	RPB3 interaction site [polypeptide binding]; other site
1132507010185	RPB1 interaction site [polypeptide binding]; other site
1132507010186	RPB11 interaction site [polypeptide binding]; other site
1132507010187	RPB10 interaction site [polypeptide binding]; other site
1132507010188	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1132507010189	core dimer interface [polypeptide binding]; other site
1132507010190	peripheral dimer interface [polypeptide binding]; other site
1132507010191	L10 interface [polypeptide binding]; other site
1132507010192	L11 interface [polypeptide binding]; other site
1132507010193	putative EF-Tu interaction site [polypeptide binding]; other site
1132507010194	putative EF-G interaction site [polypeptide binding]; other site
1132507010195	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1132507010196	23S rRNA interface [nucleotide binding]; other site
1132507010197	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1132507010198	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1132507010199	mRNA/rRNA interface [nucleotide binding]; other site
1132507010200	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1132507010201	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1132507010202	L7/L12 interface [polypeptide binding]; other site
1132507010203	23S rRNA interface [nucleotide binding]; other site
1132507010204	L25 interface [polypeptide binding]; other site
1132507010205	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1132507010206	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1132507010207	putative homodimer interface [polypeptide binding]; other site
1132507010208	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1132507010209	heterodimer interface [polypeptide binding]; other site
1132507010210	homodimer interface [polypeptide binding]; other site
1132507010211	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1132507010212	elongation factor Tu; Reviewed; Region: PRK00049
1132507010213	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1132507010214	G1 box; other site
1132507010215	GEF interaction site [polypeptide binding]; other site
1132507010216	GTP/Mg2+ binding site [chemical binding]; other site
1132507010217	Switch I region; other site
1132507010218	G2 box; other site
1132507010219	G3 box; other site
1132507010220	Switch II region; other site
1132507010221	G4 box; other site
1132507010222	G5 box; other site
1132507010223	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1132507010224	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1132507010225	Antibiotic Binding Site [chemical binding]; other site
1132507010226	pantothenate kinase; Provisional; Region: PRK05439
1132507010227	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1132507010228	ATP-binding site [chemical binding]; other site
1132507010229	CoA-binding site [chemical binding]; other site
1132507010230	Mg2+-binding site [ion binding]; other site
1132507010231	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1132507010232	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1132507010233	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1132507010234	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1132507010235	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1132507010236	FAD binding domain; Region: FAD_binding_4; pfam01565
1132507010237	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1132507010238	glutamate racemase; Provisional; Region: PRK00865
1132507010239	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1132507010240	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1132507010241	N-terminal plug; other site
1132507010242	ligand-binding site [chemical binding]; other site
1132507010243	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1132507010244	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
1132507010245	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507010246	S-adenosylmethionine binding site [chemical binding]; other site
1132507010247	hypothetical protein; Provisional; Region: PRK11056
1132507010248	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1132507010249	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507010250	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1132507010251	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507010252	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1132507010253	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1132507010254	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507010255	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1132507010256	dimerization interface [polypeptide binding]; other site
1132507010257	argininosuccinate lyase; Provisional; Region: PRK04833
1132507010258	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1132507010259	active sites [active]
1132507010260	tetramer interface [polypeptide binding]; other site
1132507010261	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1132507010262	nucleotide binding site [chemical binding]; other site
1132507010263	N-acetyl-L-glutamate binding site [chemical binding]; other site
1132507010264	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1132507010265	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1132507010266	acetylornithine deacetylase; Provisional; Region: PRK05111
1132507010267	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1132507010268	metal binding site [ion binding]; metal-binding site
1132507010269	putative dimer interface [polypeptide binding]; other site
1132507010270	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1132507010271	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1132507010272	hypothetical protein; Provisional; Region: PRK10649
1132507010273	Sulfatase; Region: Sulfatase; pfam00884
1132507010274	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1132507010275	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507010276	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1132507010277	active site
1132507010278	intersubunit interactions; other site
1132507010279	catalytic residue [active]
1132507010280	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1132507010281	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1132507010282	dimer interface [polypeptide binding]; other site
1132507010283	active site
1132507010284	metal binding site [ion binding]; metal-binding site
1132507010285	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1132507010286	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1132507010287	heme binding site [chemical binding]; other site
1132507010288	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1132507010289	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1132507010290	FAD binding site [chemical binding]; other site
1132507010291	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1132507010292	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507010293	DNA-binding site [nucleotide binding]; DNA binding site
1132507010294	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507010295	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507010296	homodimer interface [polypeptide binding]; other site
1132507010297	catalytic residue [active]
1132507010298	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
1132507010299	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1132507010300	dimer interface [polypeptide binding]; other site
1132507010301	active site
1132507010302	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1132507010303	folate binding site [chemical binding]; other site
1132507010304	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1132507010305	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1132507010306	active site
1132507010307	metal binding site [ion binding]; metal-binding site
1132507010308	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1132507010309	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1132507010310	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1132507010311	putative catalytic residues [active]
1132507010312	putative nucleotide binding site [chemical binding]; other site
1132507010313	putative aspartate binding site [chemical binding]; other site
1132507010314	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1132507010315	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1132507010316	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1132507010317	cystathionine gamma-synthase; Provisional; Region: PRK08045
1132507010318	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1132507010319	homodimer interface [polypeptide binding]; other site
1132507010320	substrate-cofactor binding pocket; other site
1132507010321	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507010322	catalytic residue [active]
1132507010323	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1132507010324	dimerization interface [polypeptide binding]; other site
1132507010325	DNA binding site [nucleotide binding]
1132507010326	corepressor binding sites; other site
1132507010327	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
1132507010328	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1132507010329	primosome assembly protein PriA; Validated; Region: PRK05580
1132507010330	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507010331	ATP binding site [chemical binding]; other site
1132507010332	putative Mg++ binding site [ion binding]; other site
1132507010333	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1132507010334	ATP-binding site [chemical binding]; other site
1132507010335	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507010336	DNA binding site [nucleotide binding]
1132507010337	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1132507010338	domain linker motif; other site
1132507010339	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1132507010340	dimerization interface [polypeptide binding]; other site
1132507010341	ligand binding site [chemical binding]; other site
1132507010342	essential cell division protein FtsN; Provisional; Region: PRK10927
1132507010343	cell division protein FtsN; Provisional; Region: PRK12757
1132507010344	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1132507010345	active site
1132507010346	HslU subunit interaction site [polypeptide binding]; other site
1132507010347	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1132507010348	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507010349	Walker A motif; other site
1132507010350	ATP binding site [chemical binding]; other site
1132507010351	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1132507010352	Walker B motif; other site
1132507010353	arginine finger; other site
1132507010354	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1132507010355	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
1132507010356	UbiA prenyltransferase family; Region: UbiA; pfam01040
1132507010357	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1132507010358	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1132507010359	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1132507010360	amphipathic channel; other site
1132507010361	Asn-Pro-Ala signature motifs; other site
1132507010362	glycerol kinase; Provisional; Region: glpK; PRK00047
1132507010363	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1132507010364	N- and C-terminal domain interface [polypeptide binding]; other site
1132507010365	active site
1132507010366	MgATP binding site [chemical binding]; other site
1132507010367	catalytic site [active]
1132507010368	metal binding site [ion binding]; metal-binding site
1132507010369	glycerol binding site [chemical binding]; other site
1132507010370	homotetramer interface [polypeptide binding]; other site
1132507010371	homodimer interface [polypeptide binding]; other site
1132507010372	FBP binding site [chemical binding]; other site
1132507010373	protein IIAGlc interface [polypeptide binding]; other site
1132507010374	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1132507010375	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1132507010376	putative active site [active]
1132507010377	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1132507010378	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1132507010379	FAD binding pocket [chemical binding]; other site
1132507010380	FAD binding motif [chemical binding]; other site
1132507010381	phosphate binding motif [ion binding]; other site
1132507010382	beta-alpha-beta structure motif; other site
1132507010383	NAD binding pocket [chemical binding]; other site
1132507010384	Predicted membrane protein [Function unknown]; Region: COG3152
1132507010385	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1132507010386	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1132507010387	triosephosphate isomerase; Provisional; Region: PRK14567
1132507010388	substrate binding site [chemical binding]; other site
1132507010389	dimer interface [polypeptide binding]; other site
1132507010390	catalytic triad [active]
1132507010391	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1132507010392	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1132507010393	substrate binding site [chemical binding]; other site
1132507010394	hexamer interface [polypeptide binding]; other site
1132507010395	metal binding site [ion binding]; metal-binding site
1132507010396	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1132507010397	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1132507010398	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1132507010399	putative active site; other site
1132507010400	catalytic residue [active]
1132507010401	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1132507010402	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1132507010403	ligand binding site [chemical binding]; other site
1132507010404	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1132507010405	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1132507010406	TM-ABC transporter signature motif; other site
1132507010407	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1132507010408	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1132507010409	TM-ABC transporter signature motif; other site
1132507010410	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1132507010411	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1132507010412	Walker A/P-loop; other site
1132507010413	ATP binding site [chemical binding]; other site
1132507010414	Q-loop/lid; other site
1132507010415	ABC transporter signature motif; other site
1132507010416	Walker B; other site
1132507010417	D-loop; other site
1132507010418	H-loop/switch region; other site
1132507010419	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1132507010420	transcriptional regulator LsrR; Provisional; Region: PRK15418
1132507010421	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1132507010422	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1132507010423	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
1132507010424	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
1132507010425	putative N- and C-terminal domain interface [polypeptide binding]; other site
1132507010426	putative active site [active]
1132507010427	putative MgATP binding site [chemical binding]; other site
1132507010428	catalytic site [active]
1132507010429	metal binding site [ion binding]; metal-binding site
1132507010430	putative carbohydrate binding site [chemical binding]; other site
1132507010431	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1132507010432	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1132507010433	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
1132507010434	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1132507010435	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507010436	DNA-binding site [nucleotide binding]; DNA binding site
1132507010437	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
1132507010438	UTRA domain; Region: UTRA; pfam07702
1132507010439	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1132507010440	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1132507010441	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1132507010442	putative substrate binding site [chemical binding]; other site
1132507010443	putative ATP binding site [chemical binding]; other site
1132507010444	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1132507010445	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1132507010446	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507010447	substrate binding pocket [chemical binding]; other site
1132507010448	membrane-bound complex binding site; other site
1132507010449	hinge residues; other site
1132507010450	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1132507010451	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1132507010452	active site
1132507010453	ADP/pyrophosphate binding site [chemical binding]; other site
1132507010454	dimerization interface [polypeptide binding]; other site
1132507010455	allosteric effector site; other site
1132507010456	fructose-1,6-bisphosphate binding site; other site
1132507010457	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1132507010458	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1132507010459	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1132507010460	dimer interface [polypeptide binding]; other site
1132507010461	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1132507010462	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507010463	active site
1132507010464	intermolecular recognition site; other site
1132507010465	dimerization interface [polypeptide binding]; other site
1132507010466	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507010467	DNA binding site [nucleotide binding]
1132507010468	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1132507010469	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507010470	dimerization interface [polypeptide binding]; other site
1132507010471	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507010472	dimer interface [polypeptide binding]; other site
1132507010473	phosphorylation site [posttranslational modification]
1132507010474	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507010475	ATP binding site [chemical binding]; other site
1132507010476	Mg2+ binding site [ion binding]; other site
1132507010477	G-X-G motif; other site
1132507010478	SnoaL-like domain; Region: SnoaL_2; pfam12680
1132507010479	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1132507010480	MOSC domain; Region: MOSC; pfam03473
1132507010481	3-alpha domain; Region: 3-alpha; pfam03475
1132507010482	superoxide dismutase; Provisional; Region: PRK10925
1132507010483	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1132507010484	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1132507010485	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1132507010486	DctM-like transporters; Region: DctM; pfam06808
1132507010487	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
1132507010488	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1132507010489	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
1132507010490	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1132507010491	transcriptional activator RhaR; Provisional; Region: PRK13502
1132507010492	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1132507010493	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507010494	transcriptional activator RhaS; Provisional; Region: PRK13503
1132507010495	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1132507010496	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507010497	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507010498	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1132507010499	N- and C-terminal domain interface [polypeptide binding]; other site
1132507010500	active site
1132507010501	putative catalytic site [active]
1132507010502	metal binding site [ion binding]; metal-binding site
1132507010503	ATP binding site [chemical binding]; other site
1132507010504	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1132507010505	carbohydrate binding site [chemical binding]; other site
1132507010506	L-rhamnose isomerase; Provisional; Region: PRK01076
1132507010507	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1132507010508	lactaldehyde reductase; Region: lactal_redase; TIGR02638
1132507010509	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1132507010510	dimer interface [polypeptide binding]; other site
1132507010511	active site
1132507010512	metal binding site [ion binding]; metal-binding site
1132507010513	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1132507010514	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1132507010515	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1132507010516	non-specific DNA binding site [nucleotide binding]; other site
1132507010517	salt bridge; other site
1132507010518	sequence-specific DNA binding site [nucleotide binding]; other site
1132507010519	Cupin domain; Region: Cupin_2; cl17218
1132507010520	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1132507010521	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1132507010522	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1132507010523	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1132507010524	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1132507010525	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1132507010526	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1132507010527	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1132507010528	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1132507010529	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1132507010530	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1132507010531	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1132507010532	oligomeric interface; other site
1132507010533	putative active site [active]
1132507010534	homodimer interface [polypeptide binding]; other site
1132507010535	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1132507010536	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
1132507010537	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1132507010538	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
1132507010539	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1132507010540	non-specific DNA binding site [nucleotide binding]; other site
1132507010541	salt bridge; other site
1132507010542	sequence-specific DNA binding site [nucleotide binding]; other site
1132507010543	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507010544	Coenzyme A binding pocket [chemical binding]; other site
1132507010545	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1132507010546	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1132507010547	putative active site [active]
1132507010548	dimerization interface [polypeptide binding]; other site
1132507010549	putative tRNAtyr binding site [nucleotide binding]; other site
1132507010550	hypothetical protein; Reviewed; Region: PRK01637
1132507010551	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1132507010552	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507010553	motif II; other site
1132507010554	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1132507010555	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1132507010556	putative DNA binding site [nucleotide binding]; other site
1132507010557	putative Zn2+ binding site [ion binding]; other site
1132507010558	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507010559	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1132507010560	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
1132507010561	substrate binding site [chemical binding]; other site
1132507010562	ATP binding site [chemical binding]; other site
1132507010563	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1132507010564	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1132507010565	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
1132507010566	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
1132507010567	dimerization interface [polypeptide binding]; other site
1132507010568	putative active cleft [active]
1132507010569	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
1132507010570	active site
1132507010571	catalytic residues [active]
1132507010572	alpha-glucosidase; Provisional; Region: PRK10426
1132507010573	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1132507010574	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
1132507010575	putative active site [active]
1132507010576	putative catalytic site [active]
1132507010577	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1132507010578	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1132507010579	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1132507010580	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507010581	putative substrate translocation pore; other site
1132507010582	outer membrane porin L; Provisional; Region: ompL; PRK09980
1132507010583	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1132507010584	Leucine-rich repeats; other site
1132507010585	Substrate binding site [chemical binding]; other site
1132507010586	Sulfatase; Region: Sulfatase; cl17466
1132507010587	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507010588	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1132507010589	active site
1132507010590	motif I; other site
1132507010591	motif II; other site
1132507010592	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507010593	GTP-binding protein; Provisional; Region: PRK10218
1132507010594	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1132507010595	G1 box; other site
1132507010596	putative GEF interaction site [polypeptide binding]; other site
1132507010597	GTP/Mg2+ binding site [chemical binding]; other site
1132507010598	Switch I region; other site
1132507010599	G2 box; other site
1132507010600	G3 box; other site
1132507010601	Switch II region; other site
1132507010602	G4 box; other site
1132507010603	G5 box; other site
1132507010604	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1132507010605	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1132507010606	glutamine synthetase; Provisional; Region: glnA; PRK09469
1132507010607	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1132507010608	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1132507010609	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1132507010610	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1132507010611	putative active site [active]
1132507010612	heme pocket [chemical binding]; other site
1132507010613	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507010614	dimer interface [polypeptide binding]; other site
1132507010615	phosphorylation site [posttranslational modification]
1132507010616	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507010617	ATP binding site [chemical binding]; other site
1132507010618	Mg2+ binding site [ion binding]; other site
1132507010619	G-X-G motif; other site
1132507010620	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1132507010621	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507010622	active site
1132507010623	phosphorylation site [posttranslational modification]
1132507010624	intermolecular recognition site; other site
1132507010625	dimerization interface [polypeptide binding]; other site
1132507010626	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507010627	Walker A motif; other site
1132507010628	ATP binding site [chemical binding]; other site
1132507010629	Walker B motif; other site
1132507010630	arginine finger; other site
1132507010631	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1132507010632	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1132507010633	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507010634	FeS/SAM binding site; other site
1132507010635	HemN C-terminal domain; Region: HemN_C; pfam06969
1132507010636	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
1132507010637	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1132507010638	G1 box; other site
1132507010639	GTP/Mg2+ binding site [chemical binding]; other site
1132507010640	Switch I region; other site
1132507010641	G2 box; other site
1132507010642	G3 box; other site
1132507010643	Switch II region; other site
1132507010644	G4 box; other site
1132507010645	G5 box; other site
1132507010646	DNA polymerase I; Provisional; Region: PRK05755
1132507010647	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1132507010648	active site
1132507010649	metal binding site 1 [ion binding]; metal-binding site
1132507010650	putative 5' ssDNA interaction site; other site
1132507010651	metal binding site 3; metal-binding site
1132507010652	metal binding site 2 [ion binding]; metal-binding site
1132507010653	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1132507010654	putative DNA binding site [nucleotide binding]; other site
1132507010655	putative metal binding site [ion binding]; other site
1132507010656	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1132507010657	active site
1132507010658	catalytic site [active]
1132507010659	substrate binding site [chemical binding]; other site
1132507010660	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1132507010661	active site
1132507010662	DNA binding site [nucleotide binding]
1132507010663	catalytic site [active]
1132507010664	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1132507010665	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1132507010666	putative acyl-acceptor binding pocket; other site
1132507010667	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1132507010668	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1132507010669	catalytic residues [active]
1132507010670	hinge region; other site
1132507010671	alpha helical domain; other site
1132507010672	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1132507010673	serine/threonine protein kinase; Provisional; Region: PRK11768
1132507010674	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1132507010675	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1132507010676	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1132507010677	GTP binding site; other site
1132507010678	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1132507010679	Walker A motif; other site
1132507010680	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1132507010681	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507010682	DNA-binding site [nucleotide binding]; DNA binding site
1132507010683	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1132507010684	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507010685	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507010686	transcriptional repressor RbsR; Provisional; Region: PRK10423
1132507010687	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507010688	DNA binding site [nucleotide binding]
1132507010689	domain linker motif; other site
1132507010690	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1132507010691	dimerization interface [polypeptide binding]; other site
1132507010692	ligand binding site [chemical binding]; other site
1132507010693	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1132507010694	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1132507010695	substrate binding site [chemical binding]; other site
1132507010696	dimer interface [polypeptide binding]; other site
1132507010697	ATP binding site [chemical binding]; other site
1132507010698	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1132507010699	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1132507010700	ligand binding site [chemical binding]; other site
1132507010701	dimerization interface [polypeptide binding]; other site
1132507010702	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1132507010703	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1132507010704	TM-ABC transporter signature motif; other site
1132507010705	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1132507010706	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1132507010707	Walker A/P-loop; other site
1132507010708	ATP binding site [chemical binding]; other site
1132507010709	Q-loop/lid; other site
1132507010710	ABC transporter signature motif; other site
1132507010711	Walker B; other site
1132507010712	D-loop; other site
1132507010713	H-loop/switch region; other site
1132507010714	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1132507010715	D-ribose pyranase; Provisional; Region: PRK11797
1132507010716	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1132507010717	potassium uptake protein; Region: kup; TIGR00794
1132507010718	regulatory ATPase RavA; Provisional; Region: PRK13531
1132507010719	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507010720	Walker A motif; other site
1132507010721	ATP binding site [chemical binding]; other site
1132507010722	Walker B motif; other site
1132507010723	arginine finger; other site
1132507010724	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1132507010725	hypothetical protein; Provisional; Region: yieM; PRK10997
1132507010726	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1132507010727	metal ion-dependent adhesion site (MIDAS); other site
1132507010728	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1132507010729	dimer interface [polypeptide binding]; other site
1132507010730	active site
1132507010731	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1132507010732	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1132507010733	putative DNA binding site [nucleotide binding]; other site
1132507010734	putative Zn2+ binding site [ion binding]; other site
1132507010735	AsnC family; Region: AsnC_trans_reg; pfam01037
1132507010736	FMN-binding protein MioC; Provisional; Region: PRK09004
1132507010737	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1132507010738	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1132507010739	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1132507010740	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1132507010741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507010742	S-adenosylmethionine binding site [chemical binding]; other site
1132507010743	ATP synthase I chain; Region: ATP_synt_I; cl09170
1132507010744	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1132507010745	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1132507010746	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1132507010747	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1132507010748	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1132507010749	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1132507010750	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1132507010751	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1132507010752	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1132507010753	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1132507010754	beta subunit interaction interface [polypeptide binding]; other site
1132507010755	Walker A motif; other site
1132507010756	ATP binding site [chemical binding]; other site
1132507010757	Walker B motif; other site
1132507010758	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1132507010759	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1132507010760	core domain interface [polypeptide binding]; other site
1132507010761	delta subunit interface [polypeptide binding]; other site
1132507010762	epsilon subunit interface [polypeptide binding]; other site
1132507010763	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1132507010764	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1132507010765	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1132507010766	alpha subunit interaction interface [polypeptide binding]; other site
1132507010767	Walker A motif; other site
1132507010768	ATP binding site [chemical binding]; other site
1132507010769	Walker B motif; other site
1132507010770	inhibitor binding site; inhibition site
1132507010771	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1132507010772	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1132507010773	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1132507010774	gamma subunit interface [polypeptide binding]; other site
1132507010775	epsilon subunit interface [polypeptide binding]; other site
1132507010776	LBP interface [polypeptide binding]; other site
1132507010777	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1132507010778	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1132507010779	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1132507010780	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1132507010781	Substrate binding site; other site
1132507010782	Mg++ binding site; other site
1132507010783	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1132507010784	active site
1132507010785	substrate binding site [chemical binding]; other site
1132507010786	CoA binding site [chemical binding]; other site
1132507010787	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1132507010788	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1132507010789	glutaminase active site [active]
1132507010790	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1132507010791	dimer interface [polypeptide binding]; other site
1132507010792	active site
1132507010793	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1132507010794	dimer interface [polypeptide binding]; other site
1132507010795	active site
1132507010796	fimbrial protein; Provisional; Region: lpfA; PRK15289
1132507010797	fimbrial chaperone protein; Provisional; Region: lfpB; PRK15290
1132507010798	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507010799	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507010800	fimbrial protein StgD; Provisional; Region: PRK15291
1132507010801	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1132507010802	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1132507010803	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1132507010804	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
1132507010805	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1132507010806	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1132507010807	shikimate binding site; other site
1132507010808	NAD(P) binding site [chemical binding]; other site
1132507010809	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1132507010810	active site
1132507010811	P-loop; other site
1132507010812	phosphorylation site [posttranslational modification]
1132507010813	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1132507010814	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1132507010815	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507010816	substrate binding pocket [chemical binding]; other site
1132507010817	membrane-bound complex binding site; other site
1132507010818	hinge residues; other site
1132507010819	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1132507010820	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507010821	dimer interface [polypeptide binding]; other site
1132507010822	conserved gate region; other site
1132507010823	putative PBP binding loops; other site
1132507010824	ABC-ATPase subunit interface; other site
1132507010825	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1132507010826	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507010827	dimer interface [polypeptide binding]; other site
1132507010828	conserved gate region; other site
1132507010829	putative PBP binding loops; other site
1132507010830	ABC-ATPase subunit interface; other site
1132507010831	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1132507010832	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1132507010833	Walker A/P-loop; other site
1132507010834	ATP binding site [chemical binding]; other site
1132507010835	Q-loop/lid; other site
1132507010836	ABC transporter signature motif; other site
1132507010837	Walker B; other site
1132507010838	D-loop; other site
1132507010839	H-loop/switch region; other site
1132507010840	transcriptional regulator PhoU; Provisional; Region: PRK11115
1132507010841	PhoU domain; Region: PhoU; pfam01895
1132507010842	PhoU domain; Region: PhoU; pfam01895
1132507010843	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1132507010844	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507010845	active site
1132507010846	motif I; other site
1132507010847	motif II; other site
1132507010848	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1132507010849	Predicted flavoprotein [General function prediction only]; Region: COG0431
1132507010850	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1132507010851	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1132507010852	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1132507010853	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507010854	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1132507010855	substrate binding pocket [chemical binding]; other site
1132507010856	dimerization interface [polypeptide binding]; other site
1132507010857	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1132507010858	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507010859	putative substrate translocation pore; other site
1132507010860	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1132507010861	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1132507010862	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1132507010863	G1 box; other site
1132507010864	GTP/Mg2+ binding site [chemical binding]; other site
1132507010865	Switch I region; other site
1132507010866	G2 box; other site
1132507010867	Switch II region; other site
1132507010868	G3 box; other site
1132507010869	G4 box; other site
1132507010870	G5 box; other site
1132507010871	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1132507010872	membrane protein insertase; Provisional; Region: PRK01318
1132507010873	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1132507010874	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1132507010875	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1132507010876	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1132507010877	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1132507010878	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507010879	Walker A motif; other site
1132507010880	ATP binding site [chemical binding]; other site
1132507010881	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1132507010882	Walker B motif; other site
1132507010883	arginine finger; other site
1132507010884	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1132507010885	DnaA box-binding interface [nucleotide binding]; other site
1132507010886	DNA polymerase III subunit beta; Validated; Region: PRK05643
1132507010887	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1132507010888	putative DNA binding surface [nucleotide binding]; other site
1132507010889	dimer interface [polypeptide binding]; other site
1132507010890	beta-clamp/clamp loader binding surface; other site
1132507010891	beta-clamp/translesion DNA polymerase binding surface; other site
1132507010892	recF protein; Region: recf; TIGR00611
1132507010893	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507010894	Walker A/P-loop; other site
1132507010895	ATP binding site [chemical binding]; other site
1132507010896	Q-loop/lid; other site
1132507010897	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507010898	ABC transporter signature motif; other site
1132507010899	Walker B; other site
1132507010900	D-loop; other site
1132507010901	H-loop/switch region; other site
1132507010902	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1132507010903	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507010904	Mg2+ binding site [ion binding]; other site
1132507010905	G-X-G motif; other site
1132507010906	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1132507010907	anchoring element; other site
1132507010908	dimer interface [polypeptide binding]; other site
1132507010909	ATP binding site [chemical binding]; other site
1132507010910	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1132507010911	active site
1132507010912	putative metal-binding site [ion binding]; other site
1132507010913	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1132507010914	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507010915	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507010916	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1132507010917	putative dimerization interface [polypeptide binding]; other site
1132507010918	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1132507010919	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1132507010920	active site pocket [active]
1132507010921	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507010922	D-galactonate transporter; Region: 2A0114; TIGR00893
1132507010923	putative substrate translocation pore; other site
1132507010924	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507010925	sugar phosphate phosphatase; Provisional; Region: PRK10513
1132507010926	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507010927	active site
1132507010928	motif I; other site
1132507010929	motif II; other site
1132507010930	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507010931	Surface antigen; Region: Bac_surface_Ag; pfam01103
1132507010932	Protein of unknown function (DUF4056); Region: DUF4056; pfam13265
1132507010933	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
1132507010934	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507010935	dimer interface [polypeptide binding]; other site
1132507010936	phosphorylation site [posttranslational modification]
1132507010937	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507010938	ATP binding site [chemical binding]; other site
1132507010939	Mg2+ binding site [ion binding]; other site
1132507010940	G-X-G motif; other site
1132507010941	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507010942	active site
1132507010943	phosphorylation site [posttranslational modification]
1132507010944	intermolecular recognition site; other site
1132507010945	dimerization interface [polypeptide binding]; other site
1132507010946	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1132507010947	putative binding surface; other site
1132507010948	active site
1132507010949	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
1132507010950	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1132507010951	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
1132507010952	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1132507010953	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
1132507010954	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1132507010955	molybdopterin cofactor binding site [chemical binding]; other site
1132507010956	substrate binding site [chemical binding]; other site
1132507010957	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1132507010958	molybdopterin cofactor binding site; other site
1132507010959	chaperone protein TorD; Validated; Region: torD; PRK04976
1132507010960	Haem-binding domain; Region: Haem_bd; pfam14376
1132507010961	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1132507010962	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507010963	Walker A/P-loop; other site
1132507010964	ATP binding site [chemical binding]; other site
1132507010965	Q-loop/lid; other site
1132507010966	ABC transporter signature motif; other site
1132507010967	Walker B; other site
1132507010968	D-loop; other site
1132507010969	H-loop/switch region; other site
1132507010970	heme exporter protein CcmB; Region: ccmB; TIGR01190
1132507010971	heme exporter protein CcmC; Region: ccmC; TIGR01191
1132507010972	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1132507010973	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1132507010974	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1132507010975	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1132507010976	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1132507010977	catalytic residues [active]
1132507010978	central insert; other site
1132507010979	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1132507010980	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1132507010981	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1132507010982	hypothetical protein; Provisional; Region: PRK11616
1132507010983	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1132507010984	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1132507010985	putative dimer interface [polypeptide binding]; other site
1132507010986	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1132507010987	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1132507010988	putative dimer interface [polypeptide binding]; other site
1132507010989	putative transporter; Validated; Region: PRK03818
1132507010990	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1132507010991	TrkA-C domain; Region: TrkA_C; pfam02080
1132507010992	TrkA-C domain; Region: TrkA_C; pfam02080
1132507010993	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1132507010994	Domain of unknown function (DUF202); Region: DUF202; cl09954
1132507010995	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1132507010996	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
1132507010997	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
1132507010998	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1132507010999	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1132507011000	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1132507011001	catalytic residue [active]
1132507011002	permease DsdX; Provisional; Region: PRK09921
1132507011003	gluconate transporter; Region: gntP; TIGR00791
1132507011004	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
1132507011005	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507011006	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1132507011007	dimerization interface [polypeptide binding]; other site
1132507011008	substrate binding pocket [chemical binding]; other site
1132507011009	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1132507011010	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507011011	putative substrate translocation pore; other site
1132507011012	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1132507011013	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1132507011014	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1132507011015	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1132507011016	PYR/PP interface [polypeptide binding]; other site
1132507011017	dimer interface [polypeptide binding]; other site
1132507011018	TPP binding site [chemical binding]; other site
1132507011019	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1132507011020	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1132507011021	TPP-binding site [chemical binding]; other site
1132507011022	dimer interface [polypeptide binding]; other site
1132507011023	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1132507011024	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1132507011025	putative valine binding site [chemical binding]; other site
1132507011026	dimer interface [polypeptide binding]; other site
1132507011027	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1132507011028	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1132507011029	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507011030	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1132507011031	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1132507011032	substrate binding site [chemical binding]; other site
1132507011033	dimer interface [polypeptide binding]; other site
1132507011034	ATP binding site [chemical binding]; other site
1132507011035	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1132507011036	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507011037	putative substrate translocation pore; other site
1132507011038	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
1132507011039	active site
1132507011040	catalytic residues [active]
1132507011041	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1132507011042	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507011043	active site
1132507011044	phosphorylation site [posttranslational modification]
1132507011045	intermolecular recognition site; other site
1132507011046	dimerization interface [polypeptide binding]; other site
1132507011047	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507011048	DNA binding residues [nucleotide binding]
1132507011049	dimerization interface [polypeptide binding]; other site
1132507011050	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1132507011051	MASE1; Region: MASE1; pfam05231
1132507011052	Histidine kinase; Region: HisKA_3; pfam07730
1132507011053	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507011054	ATP binding site [chemical binding]; other site
1132507011055	Mg2+ binding site [ion binding]; other site
1132507011056	G-X-G motif; other site
1132507011057	regulatory protein UhpC; Provisional; Region: PRK11663
1132507011058	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507011059	putative substrate translocation pore; other site
1132507011060	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1132507011061	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507011062	putative substrate translocation pore; other site
1132507011063	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1132507011064	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1132507011065	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507011066	DNA-binding site [nucleotide binding]; DNA binding site
1132507011067	UTRA domain; Region: UTRA; pfam07702
1132507011068	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1132507011069	active site
1132507011070	phosphorylation site [posttranslational modification]
1132507011071	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1132507011072	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1132507011073	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1132507011074	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1132507011075	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
1132507011076	putative N- and C-terminal domain interface [polypeptide binding]; other site
1132507011077	putative active site [active]
1132507011078	putative MgATP binding site [chemical binding]; other site
1132507011079	catalytic site [active]
1132507011080	metal binding site [ion binding]; metal-binding site
1132507011081	putative carbohydrate binding site [chemical binding]; other site
1132507011082	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1132507011083	active site
1132507011084	zinc binding site [ion binding]; other site
1132507011085	Na+ binding site [ion binding]; other site
1132507011086	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1132507011087	dimerization domain swap beta strand [polypeptide binding]; other site
1132507011088	regulatory protein interface [polypeptide binding]; other site
1132507011089	active site
1132507011090	regulatory phosphorylation site [posttranslational modification]; other site
1132507011091	Predicted transcriptional regulator [Transcription]; Region: COG2944
1132507011092	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1132507011093	non-specific DNA binding site [nucleotide binding]; other site
1132507011094	salt bridge; other site
1132507011095	sequence-specific DNA binding site [nucleotide binding]; other site
1132507011096	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1132507011097	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1132507011098	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507011099	putative substrate translocation pore; other site
1132507011100	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1132507011101	beta-galactosidase; Region: BGL; TIGR03356
1132507011102	HTH domain; Region: HTH_11; cl17392
1132507011103	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507011104	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1132507011105	Walker A motif; other site
1132507011106	ATP binding site [chemical binding]; other site
1132507011107	Walker B motif; other site
1132507011108	arginine finger; other site
1132507011109	Transcriptional antiterminator [Transcription]; Region: COG3933
1132507011110	PRD domain; Region: PRD; pfam00874
1132507011111	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1132507011112	active pocket/dimerization site; other site
1132507011113	active site
1132507011114	phosphorylation site [posttranslational modification]
1132507011115	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1132507011116	active site
1132507011117	phosphorylation site [posttranslational modification]
1132507011118	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1132507011119	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1132507011120	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1132507011121	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
1132507011122	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1132507011123	hypothetical protein; Provisional; Region: PRK09956
1132507011124	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1132507011125	EamA-like transporter family; Region: EamA; pfam00892
1132507011126	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1132507011127	EamA-like transporter family; Region: EamA; pfam00892
1132507011128	magnesium transport protein MgtC; Provisional; Region: PRK15385
1132507011129	MgtC family; Region: MgtC; pfam02308
1132507011130	magnesium-transporting ATPase; Provisional; Region: PRK15122
1132507011131	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1132507011132	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1132507011133	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1132507011134	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1132507011135	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1132507011136	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1132507011137	Isochorismatase family; Region: Isochorismatase; pfam00857
1132507011138	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1132507011139	catalytic triad [active]
1132507011140	dimer interface [polypeptide binding]; other site
1132507011141	conserved cis-peptide bond; other site
1132507011142	Transposase; Region: HTH_Tnp_1; cl17663
1132507011143	Virulence protein [General function prediction only]; Region: COG3943
1132507011144	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1132507011145	TIGR02646 family protein; Region: TIGR02646
1132507011146	putative transporter; Provisional; Region: PRK11462
1132507011147	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1132507011148	putative alpha-glucosidase; Provisional; Region: PRK10658
1132507011149	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1132507011150	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1132507011151	active site
1132507011152	homotrimer interface [polypeptide binding]; other site
1132507011153	catalytic site [active]
1132507011154	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1132507011155	AsmA family; Region: AsmA; pfam05170
1132507011156	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
1132507011157	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1132507011158	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1132507011159	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1132507011160	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1132507011161	generic binding surface II; other site
1132507011162	ssDNA binding site; other site
1132507011163	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507011164	ATP binding site [chemical binding]; other site
1132507011165	putative Mg++ binding site [ion binding]; other site
1132507011166	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507011167	nucleotide binding region [chemical binding]; other site
1132507011168	ATP-binding site [chemical binding]; other site
1132507011169	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1132507011170	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1132507011171	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1132507011172	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1132507011173	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1132507011174	Zn2+ binding site [ion binding]; other site
1132507011175	Mg2+ binding site [ion binding]; other site
1132507011176	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1132507011177	synthetase active site [active]
1132507011178	NTP binding site [chemical binding]; other site
1132507011179	metal binding site [ion binding]; metal-binding site
1132507011180	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1132507011181	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1132507011182	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1132507011183	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1132507011184	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1132507011185	catalytic site [active]
1132507011186	G-X2-G-X-G-K; other site
1132507011187	Predicted membrane protein [Function unknown]; Region: COG2860
1132507011188	UPF0126 domain; Region: UPF0126; pfam03458
1132507011189	UPF0126 domain; Region: UPF0126; pfam03458
1132507011190	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1132507011191	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507011192	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507011193	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1132507011194	dimerization interface [polypeptide binding]; other site
1132507011195	hypothetical protein; Provisional; Region: PRK11820
1132507011196	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1132507011197	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1132507011198	ribonuclease PH; Reviewed; Region: rph; PRK00173
1132507011199	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1132507011200	hexamer interface [polypeptide binding]; other site
1132507011201	active site
1132507011202	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1132507011203	active site
1132507011204	division inhibitor protein; Provisional; Region: slmA; PRK09480
1132507011205	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507011206	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1132507011207	trimer interface [polypeptide binding]; other site
1132507011208	active site
1132507011209	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1132507011210	Flavoprotein; Region: Flavoprotein; pfam02441
1132507011211	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1132507011212	hypothetical protein; Reviewed; Region: PRK00024
1132507011213	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1132507011214	MPN+ (JAMM) motif; other site
1132507011215	Zinc-binding site [ion binding]; other site
1132507011216	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1132507011217	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1132507011218	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1132507011219	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1132507011220	DNA binding site [nucleotide binding]
1132507011221	catalytic residue [active]
1132507011222	H2TH interface [polypeptide binding]; other site
1132507011223	putative catalytic residues [active]
1132507011224	turnover-facilitating residue; other site
1132507011225	intercalation triad [nucleotide binding]; other site
1132507011226	8OG recognition residue [nucleotide binding]; other site
1132507011227	putative reading head residues; other site
1132507011228	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1132507011229	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1132507011230	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1132507011231	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1132507011232	active site
1132507011233	(T/H)XGH motif; other site
1132507011234	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
1132507011235	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1132507011236	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1132507011237	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1132507011238	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1132507011239	putative active site [active]
1132507011240	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1132507011241	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1132507011242	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
1132507011243	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1132507011244	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
1132507011245	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1132507011246	putative ADP-binding pocket [chemical binding]; other site
1132507011247	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1132507011248	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1132507011249	Ligand binding site; other site
1132507011250	metal-binding site
1132507011251	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1132507011252	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1132507011253	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1132507011254	Ligand binding site; other site
1132507011255	metal-binding site
1132507011256	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1132507011257	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
1132507011258	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
1132507011259	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
1132507011260	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1132507011261	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1132507011262	O-antigen ligase RfaL; Provisional; Region: PRK15487
1132507011263	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1132507011264	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1132507011265	putative active site [active]
1132507011266	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1132507011267	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1132507011268	putative active site [active]
1132507011269	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1132507011270	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1132507011271	NADP binding site [chemical binding]; other site
1132507011272	homopentamer interface [polypeptide binding]; other site
1132507011273	substrate binding site [chemical binding]; other site
1132507011274	active site
1132507011275	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1132507011276	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1132507011277	substrate-cofactor binding pocket; other site
1132507011278	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507011279	catalytic residue [active]
1132507011280	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1132507011281	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1132507011282	NAD(P) binding site [chemical binding]; other site
1132507011283	putative glycosyl transferase; Provisional; Region: PRK10073
1132507011284	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1132507011285	active site
1132507011286	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1132507011287	NodB motif; other site
1132507011288	putative active site [active]
1132507011289	putative catalytic site [active]
1132507011290	Zn binding site [ion binding]; other site
1132507011291	AmiB activator; Provisional; Region: PRK11637
1132507011292	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1132507011293	Peptidase family M23; Region: Peptidase_M23; pfam01551
1132507011294	phosphoglyceromutase; Provisional; Region: PRK05434
1132507011295	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1132507011296	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1132507011297	active site residue [active]
1132507011298	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1132507011299	GSH binding site [chemical binding]; other site
1132507011300	catalytic residues [active]
1132507011301	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1132507011302	SecA binding site; other site
1132507011303	Preprotein binding site; other site
1132507011304	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1132507011305	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1132507011306	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1132507011307	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1132507011308	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1132507011309	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1132507011310	trimer interface [polypeptide binding]; other site
1132507011311	active site
1132507011312	substrate binding site [chemical binding]; other site
1132507011313	CoA binding site [chemical binding]; other site
1132507011314	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1132507011315	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1132507011316	active site pocket [active]
1132507011317	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1132507011318	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507011319	DNA binding site [nucleotide binding]
1132507011320	domain linker motif; other site
1132507011321	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1132507011322	putative dimerization interface [polypeptide binding]; other site
1132507011323	putative ligand binding site [chemical binding]; other site
1132507011324	putative rRNA methylase; Provisional; Region: PRK10358
1132507011325	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1132507011326	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1132507011327	active site
1132507011328	substrate binding site [chemical binding]; other site
1132507011329	FMN binding site [chemical binding]; other site
1132507011330	putative catalytic residues [active]
1132507011331	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1132507011332	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507011333	DNA-binding site [nucleotide binding]; DNA binding site
1132507011334	FCD domain; Region: FCD; pfam07729
1132507011335	L-lactate permease; Provisional; Region: PRK10420
1132507011336	glycolate transporter; Provisional; Region: PRK09695
1132507011337	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1132507011338	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
1132507011339	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1132507011340	Haemagglutinin; Region: HIM; pfam05662
1132507011341	Haemagglutinin; Region: HIM; pfam05662
1132507011342	YadA-like C-terminal region; Region: YadA; pfam03895
1132507011343	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
1132507011344	hypothetical protein; Provisional; Region: PRK11020
1132507011345	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1132507011346	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1132507011347	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1132507011348	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1132507011349	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1132507011350	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1132507011351	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1132507011352	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1132507011353	active site
1132507011354	P-loop; other site
1132507011355	phosphorylation site [posttranslational modification]
1132507011356	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1132507011357	active site
1132507011358	phosphorylation site [posttranslational modification]
1132507011359	putative glutathione S-transferase; Provisional; Region: PRK10357
1132507011360	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1132507011361	putative C-terminal domain interface [polypeptide binding]; other site
1132507011362	putative GSH binding site (G-site) [chemical binding]; other site
1132507011363	putative dimer interface [polypeptide binding]; other site
1132507011364	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1132507011365	dimer interface [polypeptide binding]; other site
1132507011366	N-terminal domain interface [polypeptide binding]; other site
1132507011367	putative substrate binding pocket (H-site) [chemical binding]; other site
1132507011368	selenocysteine synthase; Provisional; Region: PRK04311
1132507011369	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1132507011370	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1132507011371	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1132507011372	catalytic residue [active]
1132507011373	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1132507011374	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1132507011375	G1 box; other site
1132507011376	putative GEF interaction site [polypeptide binding]; other site
1132507011377	GTP/Mg2+ binding site [chemical binding]; other site
1132507011378	Switch I region; other site
1132507011379	G2 box; other site
1132507011380	G3 box; other site
1132507011381	Switch II region; other site
1132507011382	G4 box; other site
1132507011383	G5 box; other site
1132507011384	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1132507011385	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1132507011386	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1132507011387	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1132507011388	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1132507011389	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1132507011390	nucleotide binding site [chemical binding]; other site
1132507011391	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1132507011392	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1132507011393	NAD(P) binding site [chemical binding]; other site
1132507011394	catalytic residues [active]
1132507011395	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1132507011396	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1132507011397	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1132507011398	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1132507011399	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507011400	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1132507011401	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1132507011402	intersubunit interface [polypeptide binding]; other site
1132507011403	active site
1132507011404	Zn2+ binding site [ion binding]; other site
1132507011405	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1132507011406	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1132507011407	AP (apurinic/apyrimidinic) site pocket; other site
1132507011408	DNA interaction; other site
1132507011409	Metal-binding active site; metal-binding site
1132507011410	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1132507011411	active site
1132507011412	dimer interface [polypeptide binding]; other site
1132507011413	magnesium binding site [ion binding]; other site
1132507011414	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1132507011415	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1132507011416	putative N- and C-terminal domain interface [polypeptide binding]; other site
1132507011417	putative active site [active]
1132507011418	MgATP binding site [chemical binding]; other site
1132507011419	catalytic site [active]
1132507011420	metal binding site [ion binding]; metal-binding site
1132507011421	putative xylulose binding site [chemical binding]; other site
1132507011422	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1132507011423	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1132507011424	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
1132507011425	DctM-like transporters; Region: DctM; pfam06808
1132507011426	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
1132507011427	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1132507011428	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1132507011429	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1132507011430	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1132507011431	Bacterial transcriptional regulator; Region: IclR; pfam01614
1132507011432	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1132507011433	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1132507011434	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507011435	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507011436	homodimer interface [polypeptide binding]; other site
1132507011437	catalytic residue [active]
1132507011438	alpha-amylase; Reviewed; Region: malS; PRK09505
1132507011439	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1132507011440	active site
1132507011441	catalytic site [active]
1132507011442	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1132507011443	hypothetical protein; Provisional; Region: PRK10356
1132507011444	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1132507011445	putative dimerization interface [polypeptide binding]; other site
1132507011446	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1132507011447	putative ligand binding site [chemical binding]; other site
1132507011448	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507011449	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1132507011450	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507011451	xylose isomerase; Provisional; Region: PRK05474
1132507011452	xylose isomerase; Region: xylose_isom_A; TIGR02630
1132507011453	xylulokinase; Provisional; Region: PRK15027
1132507011454	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1132507011455	N- and C-terminal domain interface [polypeptide binding]; other site
1132507011456	active site
1132507011457	MgATP binding site [chemical binding]; other site
1132507011458	catalytic site [active]
1132507011459	metal binding site [ion binding]; metal-binding site
1132507011460	xylulose binding site [chemical binding]; other site
1132507011461	homodimer interface [polypeptide binding]; other site
1132507011462	yiaA/B two helix domain; Region: YiaAB; pfam05360
1132507011463	yiaA/B two helix domain; Region: YiaAB; cl01759
1132507011464	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1132507011465	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1132507011466	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1132507011467	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1132507011468	YsaB-like lipoprotein; Region: YsaB; pfam13983
1132507011469	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1132507011470	dimer interface [polypeptide binding]; other site
1132507011471	motif 1; other site
1132507011472	active site
1132507011473	motif 2; other site
1132507011474	motif 3; other site
1132507011475	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1132507011476	DALR anticodon binding domain; Region: DALR_1; pfam05746
1132507011477	Integrase core domain; Region: rve; pfam00665
1132507011478	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1132507011479	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1132507011480	DNA-binding site [nucleotide binding]; DNA binding site
1132507011481	RNA-binding motif; other site
1132507011482	Predicted transcriptional regulator [Transcription]; Region: COG2944
1132507011483	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1132507011484	salt bridge; other site
1132507011485	non-specific DNA binding site [nucleotide binding]; other site
1132507011486	sequence-specific DNA binding site [nucleotide binding]; other site
1132507011487	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1132507011488	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1132507011489	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1132507011490	dimerization interface [polypeptide binding]; other site
1132507011491	ligand binding site [chemical binding]; other site
1132507011492	NADP binding site [chemical binding]; other site
1132507011493	catalytic site [active]
1132507011494	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1132507011495	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1132507011496	ligand binding site [chemical binding]; other site
1132507011497	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1132507011498	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1132507011499	molybdopterin cofactor binding site [chemical binding]; other site
1132507011500	substrate binding site [chemical binding]; other site
1132507011501	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1132507011502	molybdopterin cofactor binding site; other site
1132507011503	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507011504	Coenzyme A binding pocket [chemical binding]; other site
1132507011505	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
1132507011506	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1132507011507	phosphoethanolamine transferase; Provisional; Region: PRK11560
1132507011508	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1132507011509	Sulfatase; Region: Sulfatase; pfam00884
1132507011510	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1132507011511	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507011512	DNA binding site [nucleotide binding]
1132507011513	domain linker motif; other site
1132507011514	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
1132507011515	putative dimerization interface [polypeptide binding]; other site
1132507011516	putative ligand binding site [chemical binding]; other site
1132507011517	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
1132507011518	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1132507011519	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1132507011520	peptide binding site [polypeptide binding]; other site
1132507011521	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1132507011522	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507011523	dimer interface [polypeptide binding]; other site
1132507011524	conserved gate region; other site
1132507011525	putative PBP binding loops; other site
1132507011526	ABC-ATPase subunit interface; other site
1132507011527	dipeptide transporter; Provisional; Region: PRK10913
1132507011528	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1132507011529	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507011530	dimer interface [polypeptide binding]; other site
1132507011531	conserved gate region; other site
1132507011532	putative PBP binding loops; other site
1132507011533	ABC-ATPase subunit interface; other site
1132507011534	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1132507011535	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507011536	Walker A/P-loop; other site
1132507011537	ATP binding site [chemical binding]; other site
1132507011538	Q-loop/lid; other site
1132507011539	ABC transporter signature motif; other site
1132507011540	Walker B; other site
1132507011541	D-loop; other site
1132507011542	H-loop/switch region; other site
1132507011543	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1132507011544	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1132507011545	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1132507011546	Walker A/P-loop; other site
1132507011547	ATP binding site [chemical binding]; other site
1132507011548	Q-loop/lid; other site
1132507011549	ABC transporter signature motif; other site
1132507011550	Walker B; other site
1132507011551	D-loop; other site
1132507011552	H-loop/switch region; other site
1132507011553	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1132507011554	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1132507011555	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1132507011556	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1132507011557	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1132507011558	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1132507011559	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
1132507011560	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
1132507011561	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
1132507011562	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
1132507011563	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1132507011564	cell division protein; Provisional; Region: PRK10037
1132507011565	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1132507011566	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1132507011567	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1132507011568	DXD motif; other site
1132507011569	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1132507011570	PilZ domain; Region: PilZ; pfam07238
1132507011571	cellulose synthase regulator protein; Provisional; Region: PRK11114
1132507011572	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1132507011573	putative diguanylate cyclase; Provisional; Region: PRK13561
1132507011574	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507011575	metal binding site [ion binding]; metal-binding site
1132507011576	active site
1132507011577	I-site; other site
1132507011578	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507011579	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1132507011580	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1132507011581	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1132507011582	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1132507011583	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1132507011584	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1132507011585	substrate binding site [chemical binding]; other site
1132507011586	ATP binding site [chemical binding]; other site
1132507011587	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507011588	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1132507011589	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1132507011590	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507011591	metabolite-proton symporter; Region: 2A0106; TIGR00883
1132507011592	putative substrate translocation pore; other site
1132507011593	inner membrane protein YhjD; Region: TIGR00766
1132507011594	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507011595	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507011596	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1132507011597	putative effector binding pocket; other site
1132507011598	putative dimerization interface [polypeptide binding]; other site
1132507011599	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1132507011600	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507011601	DNA binding residues [nucleotide binding]
1132507011602	dimerization interface [polypeptide binding]; other site
1132507011603	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
1132507011604	catalytic residue [active]
1132507011605	trehalase; Provisional; Region: treF; PRK13270
1132507011606	Trehalase; Region: Trehalase; pfam01204
1132507011607	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1132507011608	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507011609	DNA-binding site [nucleotide binding]; DNA binding site
1132507011610	UTRA domain; Region: UTRA; pfam07702
1132507011611	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1132507011612	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1132507011613	putative active site [active]
1132507011614	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1132507011615	dimer interface [polypeptide binding]; other site
1132507011616	active site
1132507011617	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cl00216
1132507011618	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cl00216
1132507011619	glutathione reductase; Validated; Region: PRK06116
1132507011620	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1132507011621	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507011622	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1132507011623	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1132507011624	hypothetical protein; Provisional; Region: PRK10215
1132507011625	oligopeptidase A; Provisional; Region: PRK10911
1132507011626	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1132507011627	active site
1132507011628	Zn binding site [ion binding]; other site
1132507011629	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507011630	S-adenosylmethionine binding site [chemical binding]; other site
1132507011631	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1132507011632	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507011633	putative substrate translocation pore; other site
1132507011634	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1132507011635	Ligand Binding Site [chemical binding]; other site
1132507011636	universal stress protein UspB; Provisional; Region: PRK04960
1132507011637	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1132507011638	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1132507011639	Predicted flavoproteins [General function prediction only]; Region: COG2081
1132507011640	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1132507011641	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1132507011642	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1132507011643	YheO-like PAS domain; Region: PAS_6; pfam08348
1132507011644	HTH domain; Region: HTH_22; pfam13309
1132507011645	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1132507011646	homotrimer interaction site [polypeptide binding]; other site
1132507011647	putative active site [active]
1132507011648	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
1132507011649	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507011650	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507011651	homodimer interface [polypeptide binding]; other site
1132507011652	catalytic residue [active]
1132507011653	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1132507011654	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507011655	HlyD family secretion protein; Region: HlyD; pfam00529
1132507011656	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1132507011657	HlyD family secretion protein; Region: HlyD_3; pfam13437
1132507011658	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1132507011659	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1132507011660	Walker A/P-loop; other site
1132507011661	ATP binding site [chemical binding]; other site
1132507011662	Q-loop/lid; other site
1132507011663	ABC transporter signature motif; other site
1132507011664	Walker B; other site
1132507011665	D-loop; other site
1132507011666	H-loop/switch region; other site
1132507011667	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1132507011668	Walker A/P-loop; other site
1132507011669	ATP binding site [chemical binding]; other site
1132507011670	Q-loop/lid; other site
1132507011671	ABC transporter signature motif; other site
1132507011672	Walker B; other site
1132507011673	D-loop; other site
1132507011674	H-loop/switch region; other site
1132507011675	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1132507011676	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1132507011677	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1132507011678	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1132507011679	nickel responsive regulator; Provisional; Region: PRK02967
1132507011680	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1132507011681	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1132507011682	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1132507011683	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1132507011684	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1132507011685	major facilitator superfamily transporter; Provisional; Region: PRK05122
1132507011686	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507011687	putative substrate translocation pore; other site
1132507011688	hypothetical protein; Provisional; Region: PRK11615
1132507011689	hypothetical protein; Provisional; Region: PRK11212
1132507011690	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1132507011691	CPxP  motif; other site
1132507011692	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1132507011693	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1132507011694	dimer interface [polypeptide binding]; other site
1132507011695	ligand binding site [chemical binding]; other site
1132507011696	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507011697	dimerization interface [polypeptide binding]; other site
1132507011698	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1132507011699	dimer interface [polypeptide binding]; other site
1132507011700	putative CheW interface [polypeptide binding]; other site
1132507011701	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1132507011702	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1132507011703	metal-binding site [ion binding]
1132507011704	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1132507011705	Predicted membrane protein [Function unknown]; Region: COG3714
1132507011706	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1132507011707	hypothetical protein; Provisional; Region: PRK10910
1132507011708	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1132507011709	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507011710	S-adenosylmethionine binding site [chemical binding]; other site
1132507011711	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1132507011712	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1132507011713	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1132507011714	P loop; other site
1132507011715	GTP binding site [chemical binding]; other site
1132507011716	cell division protein FtsE; Provisional; Region: PRK10908
1132507011717	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507011718	Walker A/P-loop; other site
1132507011719	ATP binding site [chemical binding]; other site
1132507011720	Q-loop/lid; other site
1132507011721	ABC transporter signature motif; other site
1132507011722	Walker B; other site
1132507011723	D-loop; other site
1132507011724	H-loop/switch region; other site
1132507011725	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1132507011726	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1132507011727	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1132507011728	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1132507011729	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1132507011730	DNA binding residues [nucleotide binding]
1132507011731	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1132507011732	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1132507011733	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1132507011734	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1132507011735	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1132507011736	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1132507011737	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1132507011738	dimerization interface [polypeptide binding]; other site
1132507011739	ligand binding site [chemical binding]; other site
1132507011740	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1132507011741	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1132507011742	TM-ABC transporter signature motif; other site
1132507011743	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1132507011744	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1132507011745	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1132507011746	TM-ABC transporter signature motif; other site
1132507011747	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1132507011748	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1132507011749	Walker A/P-loop; other site
1132507011750	ATP binding site [chemical binding]; other site
1132507011751	Q-loop/lid; other site
1132507011752	ABC transporter signature motif; other site
1132507011753	Walker B; other site
1132507011754	D-loop; other site
1132507011755	H-loop/switch region; other site
1132507011756	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1132507011757	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1132507011758	Walker A/P-loop; other site
1132507011759	ATP binding site [chemical binding]; other site
1132507011760	Q-loop/lid; other site
1132507011761	ABC transporter signature motif; other site
1132507011762	Walker B; other site
1132507011763	D-loop; other site
1132507011764	H-loop/switch region; other site
1132507011765	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1132507011766	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1132507011767	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1132507011768	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507011769	dimer interface [polypeptide binding]; other site
1132507011770	conserved gate region; other site
1132507011771	putative PBP binding loops; other site
1132507011772	ABC-ATPase subunit interface; other site
1132507011773	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1132507011774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507011775	dimer interface [polypeptide binding]; other site
1132507011776	conserved gate region; other site
1132507011777	ABC-ATPase subunit interface; other site
1132507011778	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1132507011779	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1132507011780	Walker A/P-loop; other site
1132507011781	ATP binding site [chemical binding]; other site
1132507011782	Q-loop/lid; other site
1132507011783	ABC transporter signature motif; other site
1132507011784	Walker B; other site
1132507011785	D-loop; other site
1132507011786	H-loop/switch region; other site
1132507011787	TOBE domain; Region: TOBE_2; pfam08402
1132507011788	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1132507011789	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1132507011790	putative active site [active]
1132507011791	catalytic site [active]
1132507011792	putative metal binding site [ion binding]; other site
1132507011793	hypothetical protein; Provisional; Region: PRK10350
1132507011794	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1132507011795	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1132507011796	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1132507011797	active site
1132507011798	substrate binding pocket [chemical binding]; other site
1132507011799	homodimer interaction site [polypeptide binding]; other site
1132507011800	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1132507011801	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1132507011802	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1132507011803	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1132507011804	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1132507011805	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1132507011806	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1132507011807	substrate binding site [chemical binding]; other site
1132507011808	dimer interface [polypeptide binding]; other site
1132507011809	ATP binding site [chemical binding]; other site
1132507011810	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1132507011811	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507011812	Coenzyme A binding pocket [chemical binding]; other site
1132507011813	putative oxidoreductase; Provisional; Region: PRK10206
1132507011814	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1132507011815	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1132507011816	Pirin-related protein [General function prediction only]; Region: COG1741
1132507011817	Pirin; Region: Pirin; pfam02678
1132507011818	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1132507011819	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507011820	DNA binding site [nucleotide binding]
1132507011821	domain linker motif; other site
1132507011822	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1132507011823	putative ligand binding site [chemical binding]; other site
1132507011824	putative dimerization interface [polypeptide binding]; other site
1132507011825	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1132507011826	low affinity gluconate transporter; Provisional; Region: PRK10472
1132507011827	gluconate transporter; Region: gntP; TIGR00791
1132507011828	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1132507011829	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1132507011830	glycogen branching enzyme; Provisional; Region: PRK05402
1132507011831	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1132507011832	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1132507011833	active site
1132507011834	catalytic site [active]
1132507011835	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1132507011836	glycogen debranching enzyme; Provisional; Region: PRK03705
1132507011837	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1132507011838	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1132507011839	active site
1132507011840	catalytic site [active]
1132507011841	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1132507011842	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1132507011843	ligand binding site; other site
1132507011844	oligomer interface; other site
1132507011845	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1132507011846	dimer interface [polypeptide binding]; other site
1132507011847	N-terminal domain interface [polypeptide binding]; other site
1132507011848	sulfate 1 binding site; other site
1132507011849	glycogen synthase; Provisional; Region: glgA; PRK00654
1132507011850	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1132507011851	ADP-binding pocket [chemical binding]; other site
1132507011852	homodimer interface [polypeptide binding]; other site
1132507011853	glycogen phosphorylase; Provisional; Region: PRK14986
1132507011854	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1132507011855	homodimer interface [polypeptide binding]; other site
1132507011856	active site pocket [active]
1132507011857	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1132507011858	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1132507011859	active site residue [active]
1132507011860	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1132507011861	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1132507011862	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1132507011863	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1132507011864	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1132507011865	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507011866	transcriptional regulator MalT; Provisional; Region: PRK04841
1132507011867	AAA ATPase domain; Region: AAA_16; pfam13191
1132507011868	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507011869	DNA binding residues [nucleotide binding]
1132507011870	dimerization interface [polypeptide binding]; other site
1132507011871	maltodextrin phosphorylase; Provisional; Region: PRK14985
1132507011872	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1132507011873	homodimer interface [polypeptide binding]; other site
1132507011874	active site pocket [active]
1132507011875	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1132507011876	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
1132507011877	high-affinity gluconate transporter; Provisional; Region: PRK14984
1132507011878	gluconate transporter; Region: gntP; TIGR00791
1132507011879	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1132507011880	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1132507011881	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1132507011882	DNA utilization protein GntX; Provisional; Region: PRK11595
1132507011883	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1132507011884	active site
1132507011885	carboxylesterase BioH; Provisional; Region: PRK10349
1132507011886	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1132507011887	hypothetical protein; Provisional; Region: PRK09956
1132507011888	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1132507011889	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1132507011890	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1132507011891	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1132507011892	G1 box; other site
1132507011893	GTP/Mg2+ binding site [chemical binding]; other site
1132507011894	Switch I region; other site
1132507011895	G2 box; other site
1132507011896	G3 box; other site
1132507011897	Switch II region; other site
1132507011898	G4 box; other site
1132507011899	G5 box; other site
1132507011900	Nucleoside recognition; Region: Gate; pfam07670
1132507011901	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1132507011902	Nucleoside recognition; Region: Gate; pfam07670
1132507011903	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1132507011904	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1132507011905	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1132507011906	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1132507011907	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1132507011908	RNA binding site [nucleotide binding]; other site
1132507011909	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1132507011910	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1132507011911	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1132507011912	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1132507011913	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507011914	active site
1132507011915	phosphorylation site [posttranslational modification]
1132507011916	intermolecular recognition site; other site
1132507011917	dimerization interface [polypeptide binding]; other site
1132507011918	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507011919	DNA binding site [nucleotide binding]
1132507011920	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1132507011921	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507011922	dimerization interface [polypeptide binding]; other site
1132507011923	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507011924	dimer interface [polypeptide binding]; other site
1132507011925	phosphorylation site [posttranslational modification]
1132507011926	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507011927	ATP binding site [chemical binding]; other site
1132507011928	G-X-G motif; other site
1132507011929	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1132507011930	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1132507011931	active site
1132507011932	substrate-binding site [chemical binding]; other site
1132507011933	metal-binding site [ion binding]
1132507011934	ATP binding site [chemical binding]; other site
1132507011935	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1132507011936	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1132507011937	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1132507011938	dimerization interface [polypeptide binding]; other site
1132507011939	domain crossover interface; other site
1132507011940	redox-dependent activation switch; other site
1132507011941	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1132507011942	RNA binding surface [nucleotide binding]; other site
1132507011943	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1132507011944	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507011945	motif II; other site
1132507011946	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1132507011947	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1132507011948	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1132507011949	ADP-ribose binding site [chemical binding]; other site
1132507011950	dimer interface [polypeptide binding]; other site
1132507011951	active site
1132507011952	nudix motif; other site
1132507011953	metal binding site [ion binding]; metal-binding site
1132507011954	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1132507011955	Transglycosylase; Region: Transgly; pfam00912
1132507011956	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1132507011957	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1132507011958	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1132507011959	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1132507011960	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
1132507011961	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1132507011962	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1132507011963	shikimate kinase; Reviewed; Region: aroK; PRK00131
1132507011964	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1132507011965	ADP binding site [chemical binding]; other site
1132507011966	magnesium binding site [ion binding]; other site
1132507011967	putative shikimate binding site; other site
1132507011968	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1132507011969	active site
1132507011970	dimer interface [polypeptide binding]; other site
1132507011971	metal binding site [ion binding]; metal-binding site
1132507011972	cell division protein DamX; Validated; Region: PRK10905
1132507011973	DNA adenine methylase; Provisional; Region: PRK10904
1132507011974	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1132507011975	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1132507011976	substrate binding site [chemical binding]; other site
1132507011977	hexamer interface [polypeptide binding]; other site
1132507011978	metal binding site [ion binding]; metal-binding site
1132507011979	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1132507011980	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1132507011981	motif I; other site
1132507011982	active site
1132507011983	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507011984	motif II; other site
1132507011985	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1132507011986	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1132507011987	active site
1132507011988	HIGH motif; other site
1132507011989	dimer interface [polypeptide binding]; other site
1132507011990	KMSKS motif; other site
1132507011991	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1132507011992	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1132507011993	siroheme synthase; Provisional; Region: cysG; PRK10637
1132507011994	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1132507011995	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1132507011996	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1132507011997	active site
1132507011998	SAM binding site [chemical binding]; other site
1132507011999	homodimer interface [polypeptide binding]; other site
1132507012000	nitrite transporter NirC; Provisional; Region: PRK11562
1132507012001	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1132507012002	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1132507012003	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1132507012004	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1132507012005	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1132507012006	putative transporter; Provisional; Region: PRK03699
1132507012007	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507012008	putative substrate translocation pore; other site
1132507012009	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1132507012010	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1132507012011	substrate binding site [chemical binding]; other site
1132507012012	hypothetical protein; Provisional; Region: PRK10204
1132507012013	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1132507012014	cell filamentation protein Fic; Provisional; Region: PRK10347
1132507012015	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1132507012016	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1132507012017	glutamine binding [chemical binding]; other site
1132507012018	catalytic triad [active]
1132507012019	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1132507012020	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1132507012021	inhibitor-cofactor binding pocket; inhibition site
1132507012022	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507012023	catalytic residue [active]
1132507012024	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1132507012025	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1132507012026	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1132507012027	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1132507012028	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1132507012029	ligand binding site [chemical binding]; other site
1132507012030	flexible hinge region; other site
1132507012031	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1132507012032	putative switch regulator; other site
1132507012033	non-specific DNA interactions [nucleotide binding]; other site
1132507012034	DNA binding site [nucleotide binding]
1132507012035	sequence specific DNA binding site [nucleotide binding]; other site
1132507012036	putative cAMP binding site [chemical binding]; other site
1132507012037	OsmC-like protein; Region: OsmC; cl00767
1132507012038	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1132507012039	active site
1132507012040	hypothetical protein; Provisional; Region: PRK04966
1132507012041	putative monooxygenase; Provisional; Region: PRK11118
1132507012042	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507012043	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507012044	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1132507012045	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507012046	Walker A/P-loop; other site
1132507012047	ATP binding site [chemical binding]; other site
1132507012048	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1132507012049	ABC transporter signature motif; other site
1132507012050	Walker B; other site
1132507012051	D-loop; other site
1132507012052	ABC transporter; Region: ABC_tran_2; pfam12848
1132507012053	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1132507012054	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1132507012055	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1132507012056	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1132507012057	TrkA-N domain; Region: TrkA_N; pfam02254
1132507012058	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1132507012059	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1132507012060	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1132507012061	phi X174 lysis protein; Provisional; Region: PRK02793
1132507012062	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1132507012063	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1132507012064	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1132507012065	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1132507012066	YheO-like PAS domain; Region: PAS_6; pfam08348
1132507012067	HTH domain; Region: HTH_22; pfam13309
1132507012068	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1132507012069	sulfur relay protein TusC; Validated; Region: PRK00211
1132507012070	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1132507012071	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1132507012072	S17 interaction site [polypeptide binding]; other site
1132507012073	S8 interaction site; other site
1132507012074	16S rRNA interaction site [nucleotide binding]; other site
1132507012075	streptomycin interaction site [chemical binding]; other site
1132507012076	23S rRNA interaction site [nucleotide binding]; other site
1132507012077	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1132507012078	30S ribosomal protein S7; Validated; Region: PRK05302
1132507012079	elongation factor G; Reviewed; Region: PRK00007
1132507012080	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1132507012081	G1 box; other site
1132507012082	putative GEF interaction site [polypeptide binding]; other site
1132507012083	GTP/Mg2+ binding site [chemical binding]; other site
1132507012084	Switch I region; other site
1132507012085	G2 box; other site
1132507012086	G3 box; other site
1132507012087	Switch II region; other site
1132507012088	G4 box; other site
1132507012089	G5 box; other site
1132507012090	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1132507012091	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1132507012092	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1132507012093	elongation factor Tu; Reviewed; Region: PRK00049
1132507012094	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1132507012095	G1 box; other site
1132507012096	GEF interaction site [polypeptide binding]; other site
1132507012097	GTP/Mg2+ binding site [chemical binding]; other site
1132507012098	Switch I region; other site
1132507012099	G2 box; other site
1132507012100	G3 box; other site
1132507012101	Switch II region; other site
1132507012102	G4 box; other site
1132507012103	G5 box; other site
1132507012104	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1132507012105	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1132507012106	Antibiotic Binding Site [chemical binding]; other site
1132507012107	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1132507012108	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1132507012109	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1132507012110	heme binding site [chemical binding]; other site
1132507012111	ferroxidase pore; other site
1132507012112	ferroxidase diiron center [ion binding]; other site
1132507012113	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1132507012114	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1132507012115	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1132507012116	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1132507012117	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1132507012118	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1132507012119	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1132507012120	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1132507012121	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1132507012122	Ribosomal protein S19; Region: Ribosomal_S19; cl00350
1132507012123	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1132507012124	protein-rRNA interface [nucleotide binding]; other site
1132507012125	putative translocon binding site; other site
1132507012126	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1132507012127	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1132507012128	G-X-X-G motif; other site
1132507012129	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1132507012130	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1132507012131	23S rRNA interface [nucleotide binding]; other site
1132507012132	5S rRNA interface [nucleotide binding]; other site
1132507012133	putative antibiotic binding site [chemical binding]; other site
1132507012134	L25 interface [polypeptide binding]; other site
1132507012135	L27 interface [polypeptide binding]; other site
1132507012136	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1132507012137	23S rRNA interface [nucleotide binding]; other site
1132507012138	putative translocon interaction site; other site
1132507012139	signal recognition particle (SRP54) interaction site; other site
1132507012140	L23 interface [polypeptide binding]; other site
1132507012141	trigger factor interaction site; other site
1132507012142	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1132507012143	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1132507012144	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1132507012145	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1132507012146	RNA binding site [nucleotide binding]; other site
1132507012147	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1132507012148	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1132507012149	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1132507012150	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1132507012151	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1132507012152	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1132507012153	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1132507012154	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1132507012155	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1132507012156	23S rRNA interface [nucleotide binding]; other site
1132507012157	5S rRNA interface [nucleotide binding]; other site
1132507012158	L27 interface [polypeptide binding]; other site
1132507012159	L5 interface [polypeptide binding]; other site
1132507012160	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1132507012161	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1132507012162	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1132507012163	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1132507012164	23S rRNA binding site [nucleotide binding]; other site
1132507012165	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1132507012166	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1132507012167	SecY translocase; Region: SecY; pfam00344
1132507012168	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1132507012169	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1132507012170	30S ribosomal protein S11; Validated; Region: PRK05309
1132507012171	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1132507012172	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1132507012173	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1132507012174	RNA binding surface [nucleotide binding]; other site
1132507012175	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1132507012176	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1132507012177	alphaNTD homodimer interface [polypeptide binding]; other site
1132507012178	alphaNTD - beta interaction site [polypeptide binding]; other site
1132507012179	alphaNTD - beta' interaction site [polypeptide binding]; other site
1132507012180	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1132507012181	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1132507012182	hypothetical protein; Provisional; Region: PRK10203
1132507012183	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1132507012184	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1132507012185	DNA binding residues [nucleotide binding]
1132507012186	dimer interface [polypeptide binding]; other site
1132507012187	metal binding site [ion binding]; metal-binding site
1132507012188	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1132507012189	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1132507012190	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1132507012191	TrkA-N domain; Region: TrkA_N; pfam02254
1132507012192	TrkA-C domain; Region: TrkA_C; pfam02080
1132507012193	TrkA-N domain; Region: TrkA_N; pfam02254
1132507012194	TrkA-C domain; Region: TrkA_C; pfam02080
1132507012195	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1132507012196	putative RNA binding site [nucleotide binding]; other site
1132507012197	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1132507012198	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507012199	S-adenosylmethionine binding site [chemical binding]; other site
1132507012200	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1132507012201	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1132507012202	putative active site [active]
1132507012203	substrate binding site [chemical binding]; other site
1132507012204	putative cosubstrate binding site; other site
1132507012205	catalytic site [active]
1132507012206	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1132507012207	substrate binding site [chemical binding]; other site
1132507012208	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1132507012209	active site
1132507012210	catalytic residues [active]
1132507012211	metal binding site [ion binding]; metal-binding site
1132507012212	hypothetical protein; Provisional; Region: PRK10736
1132507012213	DNA protecting protein DprA; Region: dprA; TIGR00732
1132507012214	hypothetical protein; Validated; Region: PRK03430
1132507012215	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1132507012216	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1132507012217	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1132507012218	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1132507012219	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1132507012220	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1132507012221	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1132507012222	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1132507012223	shikimate binding site; other site
1132507012224	NAD(P) binding site [chemical binding]; other site
1132507012225	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1132507012226	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1132507012227	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1132507012228	trimer interface [polypeptide binding]; other site
1132507012229	putative metal binding site [ion binding]; other site
1132507012230	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1132507012231	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507012232	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1132507012233	Coenzyme A binding pocket [chemical binding]; other site
1132507012234	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1132507012235	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1132507012236	proposed active site lysine [active]
1132507012237	conserved cys residue [active]
1132507012238	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1132507012239	malate synthase A; Region: malate_syn_A; TIGR01344
1132507012240	active site
1132507012241	isocitrate lyase; Provisional; Region: PRK15063
1132507012242	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1132507012243	tetramer interface [polypeptide binding]; other site
1132507012244	active site
1132507012245	Mg2+/Mn2+ binding site [ion binding]; other site
1132507012246	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1132507012247	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1132507012248	transcriptional repressor IclR; Provisional; Region: PRK11569
1132507012249	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1132507012250	Bacterial transcriptional regulator; Region: IclR; pfam01614
1132507012251	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1132507012252	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1132507012253	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1132507012254	substrate binding pocket [chemical binding]; other site
1132507012255	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1132507012256	B12 binding site [chemical binding]; other site
1132507012257	cobalt ligand [ion binding]; other site
1132507012258	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1132507012259	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1132507012260	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1132507012261	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1132507012262	active site pocket [active]
1132507012263	oxyanion hole [active]
1132507012264	catalytic triad [active]
1132507012265	active site nucleophile [active]
1132507012266	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1132507012267	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1132507012268	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1132507012269	RNA binding surface [nucleotide binding]; other site
1132507012270	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1132507012271	probable active site [active]
1132507012272	hypothetical protein; Provisional; Region: PRK10515
1132507012273	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1132507012274	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1132507012275	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507012276	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1132507012277	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1132507012278	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
1132507012279	active site
1132507012280	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1132507012281	phosphate binding site [ion binding]; other site
1132507012282	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1132507012283	aspartate kinase III; Validated; Region: PRK09084
1132507012284	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1132507012285	nucleotide binding site [chemical binding]; other site
1132507012286	substrate binding site [chemical binding]; other site
1132507012287	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1132507012288	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1132507012289	dimer interface [polypeptide binding]; other site
1132507012290	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1132507012291	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1132507012292	active site
1132507012293	dimer interface [polypeptide binding]; other site
1132507012294	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1132507012295	dimer interface [polypeptide binding]; other site
1132507012296	active site
1132507012297	Exopolysaccharide production protein YjbE; Region: YjbE; pfam11106
1132507012298	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1132507012299	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1132507012300	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1132507012301	Predicted membrane protein [Function unknown]; Region: COG3223
1132507012302	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1132507012303	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507012304	dimer interface [polypeptide binding]; other site
1132507012305	conserved gate region; other site
1132507012306	putative PBP binding loops; other site
1132507012307	ABC-ATPase subunit interface; other site
1132507012308	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1132507012309	dimer interface [polypeptide binding]; other site
1132507012310	conserved gate region; other site
1132507012311	putative PBP binding loops; other site
1132507012312	ABC-ATPase subunit interface; other site
1132507012313	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1132507012314	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1132507012315	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1132507012316	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1132507012317	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1132507012318	Walker A/P-loop; other site
1132507012319	ATP binding site [chemical binding]; other site
1132507012320	Q-loop/lid; other site
1132507012321	ABC transporter signature motif; other site
1132507012322	Walker B; other site
1132507012323	D-loop; other site
1132507012324	H-loop/switch region; other site
1132507012325	TOBE domain; Region: TOBE_2; pfam08402
1132507012326	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1132507012327	trimer interface; other site
1132507012328	sugar binding site [chemical binding]; other site
1132507012329	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1132507012330	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1132507012331	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1132507012332	UbiA prenyltransferase family; Region: UbiA; pfam01040
1132507012333	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1132507012334	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1132507012335	putative acyl-acceptor binding pocket; other site
1132507012336	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1132507012337	LexA repressor; Validated; Region: PRK00215
1132507012338	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1132507012339	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1132507012340	Catalytic site [active]
1132507012341	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1132507012342	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1132507012343	hypothetical protein; Provisional; Region: PRK10428
1132507012344	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1132507012345	metal binding site 2 [ion binding]; metal-binding site
1132507012346	putative DNA binding helix; other site
1132507012347	metal binding site 1 [ion binding]; metal-binding site
1132507012348	dimer interface [polypeptide binding]; other site
1132507012349	structural Zn2+ binding site [ion binding]; other site
1132507012350	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1132507012351	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1132507012352	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1132507012353	FMN binding site [chemical binding]; other site
1132507012354	active site
1132507012355	catalytic residues [active]
1132507012356	substrate binding site [chemical binding]; other site
1132507012357	phage shock protein G; Reviewed; Region: pspG; PRK09459
1132507012358	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1132507012359	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1132507012360	NADP binding site [chemical binding]; other site
1132507012361	dimer interface [polypeptide binding]; other site
1132507012362	replicative DNA helicase; Provisional; Region: PRK08006
1132507012363	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1132507012364	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1132507012365	Walker A motif; other site
1132507012366	ATP binding site [chemical binding]; other site
1132507012367	Walker B motif; other site
1132507012368	DNA binding loops [nucleotide binding]
1132507012369	alanine racemase; Reviewed; Region: alr; PRK00053
1132507012370	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1132507012371	active site
1132507012372	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1132507012373	substrate binding site [chemical binding]; other site
1132507012374	catalytic residues [active]
1132507012375	dimer interface [polypeptide binding]; other site
1132507012376	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1132507012377	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1132507012378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507012379	homodimer interface [polypeptide binding]; other site
1132507012380	catalytic residue [active]
1132507012381	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507012382	active site
1132507012383	motif I; other site
1132507012384	motif II; other site
1132507012385	Uncharacterized conserved protein [Function unknown]; Region: COG0432
1132507012386	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1132507012387	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1132507012388	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1132507012389	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1132507012390	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1132507012391	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1132507012392	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1132507012393	dimer interface [polypeptide binding]; other site
1132507012394	ssDNA binding site [nucleotide binding]; other site
1132507012395	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1132507012396	hypothetical protein; Validated; Region: PRK09039
1132507012397	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
1132507012398	Outer membrane efflux protein; Region: OEP; pfam02321
1132507012399	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1132507012400	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1132507012401	HlyD family secretion protein; Region: HlyD_3; pfam13437
1132507012402	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012403	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012404	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012405	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012406	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012407	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1132507012408	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1132507012409	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012410	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1132507012411	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1132507012412	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012413	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1132507012414	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1132507012415	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012416	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1132507012417	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1132507012418	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012419	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1132507012420	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012421	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1132507012422	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012423	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012424	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012425	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1132507012426	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012427	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012428	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012429	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012430	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012431	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012432	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1132507012433	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012434	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012435	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012436	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012437	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
1132507012438	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012439	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012440	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012441	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012442	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1132507012443	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1132507012444	Walker A/P-loop; other site
1132507012445	ATP binding site [chemical binding]; other site
1132507012446	Q-loop/lid; other site
1132507012447	ABC transporter signature motif; other site
1132507012448	Walker B; other site
1132507012449	D-loop; other site
1132507012450	H-loop/switch region; other site
1132507012451	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1132507012452	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1132507012453	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1132507012454	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1132507012455	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507012456	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1132507012457	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1132507012458	DNA binding residues [nucleotide binding]
1132507012459	dimer interface [polypeptide binding]; other site
1132507012460	[2Fe-2S] cluster binding site [ion binding]; other site
1132507012461	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1132507012462	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1132507012463	putative C-terminal domain interface [polypeptide binding]; other site
1132507012464	putative GSH binding site (G-site) [chemical binding]; other site
1132507012465	putative dimer interface [polypeptide binding]; other site
1132507012466	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
1132507012467	putative N-terminal domain interface [polypeptide binding]; other site
1132507012468	putative dimer interface [polypeptide binding]; other site
1132507012469	putative substrate binding pocket (H-site) [chemical binding]; other site
1132507012470	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1132507012471	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1132507012472	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1132507012473	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1132507012474	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507012475	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1132507012476	putative dimerization interface [polypeptide binding]; other site
1132507012477	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1132507012478	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1132507012479	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1132507012480	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1132507012481	Na binding site [ion binding]; other site
1132507012482	Predicted membrane protein [Function unknown]; Region: COG3162
1132507012483	acetyl-CoA synthetase; Provisional; Region: PRK00174
1132507012484	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1132507012485	active site
1132507012486	CoA binding site [chemical binding]; other site
1132507012487	acyl-activating enzyme (AAE) consensus motif; other site
1132507012488	AMP binding site [chemical binding]; other site
1132507012489	acetate binding site [chemical binding]; other site
1132507012490	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1132507012491	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
1132507012492	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1132507012493	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
1132507012494	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1132507012495	heme lyase subunit NrfE; Provisional; Region: PRK10369
1132507012496	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
1132507012497	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1132507012498	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1132507012499	binding surface
1132507012500	TPR motif; other site
1132507012501	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1132507012502	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1132507012503	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1132507012504	Sel1-like repeats; Region: SEL1; smart00671
1132507012505	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
1132507012506	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507012507	Coenzyme A binding pocket [chemical binding]; other site
1132507012508	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1132507012509	dimer interface [polypeptide binding]; other site
1132507012510	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1132507012511	hypothetical protein; Provisional; Region: PRK10220
1132507012512	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1132507012513	PhnA protein; Region: PhnA; pfam03831
1132507012514	proline/glycine betaine transporter; Provisional; Region: PRK10642
1132507012515	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507012516	putative substrate translocation pore; other site
1132507012517	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1132507012518	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1132507012519	HAMP domain; Region: HAMP; pfam00672
1132507012520	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507012521	dimer interface [polypeptide binding]; other site
1132507012522	phosphorylation site [posttranslational modification]
1132507012523	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507012524	ATP binding site [chemical binding]; other site
1132507012525	Mg2+ binding site [ion binding]; other site
1132507012526	G-X-G motif; other site
1132507012527	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1132507012528	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507012529	active site
1132507012530	phosphorylation site [posttranslational modification]
1132507012531	intermolecular recognition site; other site
1132507012532	dimerization interface [polypeptide binding]; other site
1132507012533	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507012534	DNA binding site [nucleotide binding]
1132507012535	putative metal dependent hydrolase; Provisional; Region: PRK11598
1132507012536	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1132507012537	Sulfatase; Region: Sulfatase; pfam00884
1132507012538	arginine:agmatin antiporter; Provisional; Region: PRK10644
1132507012539	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
1132507012540	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507012541	arginine decarboxylase; Provisional; Region: PRK15029
1132507012542	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1132507012543	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1132507012544	homodimer interface [polypeptide binding]; other site
1132507012545	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1132507012546	catalytic residue [active]
1132507012547	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1132507012548	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
1132507012549	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507012550	alpha-galactosidase; Provisional; Region: PRK15076
1132507012551	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1132507012552	NAD binding site [chemical binding]; other site
1132507012553	sugar binding site [chemical binding]; other site
1132507012554	divalent metal binding site [ion binding]; other site
1132507012555	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1132507012556	dimer interface [polypeptide binding]; other site
1132507012557	melibiose:sodium symporter; Provisional; Region: PRK10429
1132507012558	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1132507012559	fumarate hydratase; Provisional; Region: PRK15389
1132507012560	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1132507012561	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1132507012562	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1132507012563	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1132507012564	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1132507012565	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507012566	active site
1132507012567	phosphorylation site [posttranslational modification]
1132507012568	intermolecular recognition site; other site
1132507012569	dimerization interface [polypeptide binding]; other site
1132507012570	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1132507012571	PAS domain; Region: PAS; smart00091
1132507012572	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507012573	ATP binding site [chemical binding]; other site
1132507012574	Mg2+ binding site [ion binding]; other site
1132507012575	G-X-G motif; other site
1132507012576	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1132507012577	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1132507012578	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
1132507012579	SdiA-regulated; Region: SdiA-regulated; pfam06977
1132507012580	SdiA-regulated; Region: SdiA-regulated; cd09971
1132507012581	putative active site [active]
1132507012582	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1132507012583	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1132507012584	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507012585	DNA binding residues [nucleotide binding]
1132507012586	dimerization interface [polypeptide binding]; other site
1132507012587	AraC family transcriptional regulator; Provisional; Region: PRK15186
1132507012588	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507012589	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1132507012590	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507012591	Coenzyme A binding pocket [chemical binding]; other site
1132507012592	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1132507012593	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1132507012594	active site
1132507012595	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1132507012596	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1132507012597	P-loop; other site
1132507012598	Magnesium ion binding site [ion binding]; other site
1132507012599	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1132507012600	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1132507012601	replicative DNA helicase; Region: DnaB; TIGR00665
1132507012602	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1132507012603	Walker A motif; other site
1132507012604	ATP binding site [chemical binding]; other site
1132507012605	Walker B motif; other site
1132507012606	DNA binding loops [nucleotide binding]
1132507012607	integrating conjugative element, PFGI_1 class, ParB family protein; Region: ICE_PFGI_1_parB; TIGR03764
1132507012608	Protein of unknown function (DUF2786); Region: DUF2786; pfam10979
1132507012609	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
1132507012610	Helix-turn-helix domain; Region: HTH_36; pfam13730
1132507012611	integrating conjugative element protein, PFL_4669 family; Region: ICE_PFL4669; TIGR03761
1132507012612	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
1132507012613	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1132507012614	active site
1132507012615	putative interdomain interaction site [polypeptide binding]; other site
1132507012616	putative metal-binding site [ion binding]; other site
1132507012617	putative nucleotide binding site [chemical binding]; other site
1132507012618	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1132507012619	domain I; other site
1132507012620	DNA binding groove [nucleotide binding]
1132507012621	phosphate binding site [ion binding]; other site
1132507012622	domain II; other site
1132507012623	domain III; other site
1132507012624	nucleotide binding site [chemical binding]; other site
1132507012625	catalytic site [active]
1132507012626	domain IV; other site
1132507012627	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1132507012628	Protein of unknown function (DUF3577); Region: DUF3577; pfam12101
1132507012629	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1132507012630	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1132507012631	dimer interface [polypeptide binding]; other site
1132507012632	ssDNA binding site [nucleotide binding]; other site
1132507012633	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1132507012634	putative single-stranded DNA-binding protein; Region: PHA01740
1132507012635	conjugative transfer region protein, TIGR03748 family; Region: conj_PilL
1132507012636	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
1132507012637	PilM; Region: PilM; pfam07419
1132507012638	Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864
1132507012639	type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021
1132507012640	Type II/IV secretion system protein; Region: T2SE; pfam00437
1132507012641	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1132507012642	Walker A motif; other site
1132507012643	ATP binding site [chemical binding]; other site
1132507012644	Walker B motif; other site
1132507012645	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1132507012646	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1132507012647	PilS N terminal; Region: PilS; pfam08805
1132507012648	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1132507012649	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1132507012650	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1132507012651	catalytic residue [active]
1132507012652	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1132507012653	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
1132507012654	Rci recombinase, C-terminal catalytic domain.  Rci enzymes are found in IncI1 incompatibility group plasmids such as R64.  These recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain...; Region: INT_Rci; cd00796
1132507012655	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1132507012656	catalytic residues [active]
1132507012657	Int/Topo IB signature motif; other site
1132507012658	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1132507012659	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
1132507012660	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1132507012661	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1132507012662	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
1132507012663	Restriction endonuclease; Region: Mrr_cat; pfam04471
1132507012664	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
1132507012665	conjugative coupling factor TraD, TOL family; Region: conj_TOL_TraD; TIGR03754
1132507012666	integrating conjugative element membrane protein, PFL_4697 family; Region: conj_TIGR03747
1132507012667	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
1132507012668	integrative conjugative element protein, RAQPRD family; Region: ICE_RAQPRD; TIGR01690
1132507012669	Protein of unknown function (DUF3262); Region: DUF3262; pfam11660
1132507012670	integrating conjugative element membrane protein, PFL_4702 family; Region: conj_TIGR03745
1132507012671	integrating conjugative element protein, PFL_4703 family; Region: conj_TIGR03746
1132507012672	Protein of unknown function (DUF3438); Region: DUF3438; pfam11920
1132507012673	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
1132507012674	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
1132507012675	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
1132507012676	integrating conjugative element protein, PFL_4709 family; Region: conj_TIGR03757
1132507012677	integrating conjugative element protein, PFL_4710 family; Region: conj_TIGR03756
1132507012678	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
1132507012679	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
1132507012680	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1132507012681	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1132507012682	Active Sites [active]
1132507012683	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1132507012684	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1132507012685	ParB-like nuclease domain; Region: ParB; smart00470
1132507012686	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1132507012687	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
1132507012688	Integrase; Region: Integrase_1; pfam12835
1132507012689	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
1132507012690	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1132507012691	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1132507012692	Protein of unknown function (DUF3085); Region: DUF3085; pfam11284
1132507012693	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1132507012694	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1132507012695	active site
1132507012696	DNA binding site [nucleotide binding]
1132507012697	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1132507012698	tail protein; Provisional; Region: D; PHA02561
1132507012699	Phage protein U [General function prediction only]; Region: COG3499
1132507012700	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1132507012701	membrane protein P6; Region: PHA01399
1132507012702	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1132507012703	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1132507012704	major tail tube protein; Provisional; Region: FII; PHA02600
1132507012705	major tail sheath protein; Provisional; Region: FI; PHA02560
1132507012706	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1132507012707	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1132507012708	DNA-binding interface [nucleotide binding]; DNA binding site
1132507012709	SopE GEF domain; Region: SopE_GEF; pfam07487
1132507012710	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1132507012711	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1132507012712	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1132507012713	baseplate assembly protein; Provisional; Region: J; PHA02568
1132507012714	baseplate wedge subunit; Provisional; Region: W; PHA02516
1132507012715	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1132507012716	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1132507012717	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1132507012718	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1132507012719	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1132507012720	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1132507012721	catalytic residues [active]
1132507012722	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
1132507012723	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1132507012724	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1132507012725	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1132507012726	capsid protein; Provisional; Region: N; PHA02538
1132507012727	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
1132507012728	terminase ATPase subunit; Provisional; Region: P; PHA02535
1132507012729	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1132507012730	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
1132507012731	portal vertex protein; Provisional; Region: Q; PHA02536
1132507012732	Phage portal protein; Region: Phage_portal; pfam04860
1132507012733	Hydrophobic surface binding protein A; Region: HsbA; pfam12296
1132507012734	DinI-like family; Region: DinI; pfam06183
1132507012735	DNA adenine methylase (dam); Region: dam; TIGR00571
1132507012736	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1132507012737	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1132507012738	active site
1132507012739	catalytic site [active]
1132507012740	substrate binding site [chemical binding]; other site
1132507012741	DksA-like zinc finger domain containing protein; Region: PHA00080
1132507012742	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1132507012743	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
1132507012744	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
1132507012745	Predicted transcriptional regulator [Transcription]; Region: COG2932
1132507012746	integrase; Provisional; Region: int; PHA02601
1132507012747	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1132507012748	dimer interface [polypeptide binding]; other site
1132507012749	active site
1132507012750	catalytic residues [active]
1132507012751	Int/Topo IB signature motif; other site
1132507012752	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1132507012753	Catalytic site [active]
1132507012754	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1132507012755	hypothetical protein; Provisional; Region: PRK13687
1132507012756	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507012757	S-adenosylmethionine binding site [chemical binding]; other site
1132507012758	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1132507012759	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507012760	S-adenosylmethionine binding site [chemical binding]; other site
1132507012761	Vi polysaccharide export protein VexE; Provisional; Region: PRK15174
1132507012762	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1132507012763	TPR motif; other site
1132507012764	binding surface
1132507012765	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
1132507012766	putative acyl-acceptor binding pocket; other site
1132507012767	Vi polysaccharide export inner membrane protein VexD; Provisional; Region: PRK15178
1132507012768	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1132507012769	Vi polysaccharide export ATP-binding protein VexC; Provisional; Region: PRK15177
1132507012770	Walker A/P-loop; other site
1132507012771	ATP binding site [chemical binding]; other site
1132507012772	Q-loop/lid; other site
1132507012773	ABC transporter signature motif; other site
1132507012774	Walker B; other site
1132507012775	D-loop; other site
1132507012776	H-loop/switch region; other site
1132507012777	Vi polysaccharide export inner membrane protein VexB; Provisional; Region: PRK15176
1132507012778	Vi polysaccharide export protein VexA; Provisional; Region: PRK15175
1132507012779	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1132507012780	Vi polysaccharide biosynthesis protein TviE; Provisional; Region: PRK15490
1132507012781	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
1132507012782	Vi polysaccharide biosynthesis protein TviD; Provisional; Region: PRK15180
1132507012783	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
1132507012784	UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256
1132507012785	NAD binding site [chemical binding]; other site
1132507012786	substrate binding site [chemical binding]; other site
1132507012787	homodimer interface [polypeptide binding]; other site
1132507012788	active site
1132507012789	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
1132507012790	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1132507012791	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1132507012792	Vi polysaccharide biosynthesis protein TviA; Provisional; Region: PRK15183
1132507012793	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1132507012794	Family description; Region: UvrD_C_2; pfam13538
1132507012795	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
1132507012796	Putative helicase; Region: TraI_2; pfam07514
1132507012797	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
1132507012798	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1132507012799	active site
1132507012800	catalytic residues [active]
1132507012801	DNA binding site [nucleotide binding]
1132507012802	Int/Topo IB signature motif; other site
1132507012803	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1132507012804	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507012805	Coenzyme A binding pocket [chemical binding]; other site
1132507012806	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
1132507012807	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
1132507012808	Integrase; Region: Integrase_1; pfam12835
1132507012809	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1132507012810	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1132507012811	integrase; Provisional; Region: PRK09692
1132507012812	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1132507012813	active site
1132507012814	Int/Topo IB signature motif; other site
1132507012815	putative transcriptional regulator; Provisional; Region: PRK11640
1132507012816	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1132507012817	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1132507012818	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1132507012819	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1132507012820	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1132507012821	DsbD alpha interface [polypeptide binding]; other site
1132507012822	catalytic residues [active]
1132507012823	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1132507012824	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1132507012825	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1132507012826	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1132507012827	Aspartase; Region: Aspartase; cd01357
1132507012828	active sites [active]
1132507012829	tetramer interface [polypeptide binding]; other site
1132507012830	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1132507012831	putative transporter; Provisional; Region: PRK11021
1132507012832	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1132507012833	oligomerisation interface [polypeptide binding]; other site
1132507012834	mobile loop; other site
1132507012835	roof hairpin; other site
1132507012836	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1132507012837	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1132507012838	ring oligomerisation interface [polypeptide binding]; other site
1132507012839	ATP/Mg binding site [chemical binding]; other site
1132507012840	stacking interactions; other site
1132507012841	hinge regions; other site
1132507012842	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1132507012843	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1132507012844	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507012845	FeS/SAM binding site; other site
1132507012846	elongation factor P; Validated; Region: PRK00529
1132507012847	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1132507012848	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1132507012849	RNA binding site [nucleotide binding]; other site
1132507012850	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1132507012851	RNA binding site [nucleotide binding]; other site
1132507012852	Predicted small secreted protein [Function unknown]; Region: COG5510
1132507012853	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1132507012854	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507012855	DNA binding residues [nucleotide binding]
1132507012856	dimerization interface [polypeptide binding]; other site
1132507012857	multidrug efflux system protein; Provisional; Region: PRK11431
1132507012858	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1132507012859	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1132507012860	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1132507012861	Iron-sulfur protein interface; other site
1132507012862	proximal quinone binding site [chemical binding]; other site
1132507012863	C-subunit interface; other site
1132507012864	distal quinone binding site; other site
1132507012865	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1132507012866	D-subunit interface [polypeptide binding]; other site
1132507012867	Iron-sulfur protein interface; other site
1132507012868	proximal quinone binding site [chemical binding]; other site
1132507012869	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1132507012870	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1132507012871	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1132507012872	L-aspartate oxidase; Provisional; Region: PRK06175
1132507012873	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1132507012874	poxB regulator PoxA; Provisional; Region: PRK09350
1132507012875	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1132507012876	motif 1; other site
1132507012877	dimer interface [polypeptide binding]; other site
1132507012878	active site
1132507012879	motif 2; other site
1132507012880	motif 3; other site
1132507012881	inner membrane transporter YjeM; Provisional; Region: PRK15238
1132507012882	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1132507012883	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1132507012884	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1132507012885	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1132507012886	GTPase RsgA; Reviewed; Region: PRK12288
1132507012887	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1132507012888	RNA binding site [nucleotide binding]; other site
1132507012889	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1132507012890	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1132507012891	GTP/Mg2+ binding site [chemical binding]; other site
1132507012892	G4 box; other site
1132507012893	G5 box; other site
1132507012894	G1 box; other site
1132507012895	Switch I region; other site
1132507012896	G2 box; other site
1132507012897	G3 box; other site
1132507012898	Switch II region; other site
1132507012899	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1132507012900	catalytic site [active]
1132507012901	putative active site [active]
1132507012902	putative substrate binding site [chemical binding]; other site
1132507012903	dimer interface [polypeptide binding]; other site
1132507012904	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1132507012905	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1132507012906	substrate binding pocket [chemical binding]; other site
1132507012907	membrane-bound complex binding site; other site
1132507012908	hinge residues; other site
1132507012909	epoxyqueuosine reductase; Region: TIGR00276
1132507012910	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1132507012911	putative carbohydrate kinase; Provisional; Region: PRK10565
1132507012912	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1132507012913	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1132507012914	putative substrate binding site [chemical binding]; other site
1132507012915	putative ATP binding site [chemical binding]; other site
1132507012916	ADP-binding protein; Provisional; Region: PRK10646
1132507012917	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1132507012918	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1132507012919	active site
1132507012920	metal binding site [ion binding]; metal-binding site
1132507012921	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1132507012922	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507012923	ATP binding site [chemical binding]; other site
1132507012924	Mg2+ binding site [ion binding]; other site
1132507012925	G-X-G motif; other site
1132507012926	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1132507012927	ATP binding site [chemical binding]; other site
1132507012928	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1132507012929	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1132507012930	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1132507012931	bacterial Hfq-like; Region: Hfq; cd01716
1132507012932	hexamer interface [polypeptide binding]; other site
1132507012933	Sm1 motif; other site
1132507012934	RNA binding site [nucleotide binding]; other site
1132507012935	Sm2 motif; other site
1132507012936	GTPase HflX; Provisional; Region: PRK11058
1132507012937	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1132507012938	HflX GTPase family; Region: HflX; cd01878
1132507012939	G1 box; other site
1132507012940	GTP/Mg2+ binding site [chemical binding]; other site
1132507012941	Switch I region; other site
1132507012942	G2 box; other site
1132507012943	G3 box; other site
1132507012944	Switch II region; other site
1132507012945	G4 box; other site
1132507012946	G5 box; other site
1132507012947	FtsH protease regulator HflK; Provisional; Region: PRK10930
1132507012948	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1132507012949	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1132507012950	FtsH protease regulator HflC; Provisional; Region: PRK11029
1132507012951	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1132507012952	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1132507012953	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1132507012954	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1132507012955	GDP-binding site [chemical binding]; other site
1132507012956	ACT binding site; other site
1132507012957	IMP binding site; other site
1132507012958	Predicted transcriptional regulator [Transcription]; Region: COG1959
1132507012959	transcriptional repressor NsrR; Provisional; Region: PRK11014
1132507012960	exoribonuclease R; Provisional; Region: PRK11642
1132507012961	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1132507012962	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1132507012963	RNB domain; Region: RNB; pfam00773
1132507012964	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1132507012965	RNA binding site [nucleotide binding]; other site
1132507012966	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1132507012967	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1132507012968	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1132507012969	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
1132507012970	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1132507012971	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
1132507012972	Predicted membrane protein [Function unknown]; Region: COG3766
1132507012973	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1132507012974	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1132507012975	Predicted integral membrane protein [Function unknown]; Region: COG5463
1132507012976	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1132507012977	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1132507012978	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1132507012979	FAD binding site [chemical binding]; other site
1132507012980	substrate binding site [chemical binding]; other site
1132507012981	catalytic residues [active]
1132507012982	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1132507012983	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1132507012984	esterase; Provisional; Region: PRK10566
1132507012985	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1132507012986	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1132507012987	transcriptional repressor UlaR; Provisional; Region: PRK13509
1132507012988	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1132507012989	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1132507012990	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1132507012991	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1132507012992	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1132507012993	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1132507012994	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
1132507012995	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1132507012996	active site
1132507012997	phosphorylation site [posttranslational modification]
1132507012998	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1132507012999	active site
1132507013000	dimer interface [polypeptide binding]; other site
1132507013001	magnesium binding site [ion binding]; other site
1132507013002	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1132507013003	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1132507013004	AP (apurinic/apyrimidinic) site pocket; other site
1132507013005	DNA interaction; other site
1132507013006	Metal-binding active site; metal-binding site
1132507013007	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1132507013008	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1132507013009	intersubunit interface [polypeptide binding]; other site
1132507013010	active site
1132507013011	Zn2+ binding site [ion binding]; other site
1132507013012	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1132507013013	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1132507013014	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1132507013015	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1132507013016	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1132507013017	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1132507013018	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1132507013019	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1132507013020	EamA-like transporter family; Region: EamA; pfam00892
1132507013021	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1132507013022	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1132507013023	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1132507013024	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1132507013025	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1132507013026	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1132507013027	DKNYY family; Region: DKNYY; pfam13644
1132507013028	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1132507013029	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1132507013030	Hemerythrin-like domain; Region: Hr-like; cd12108
1132507013031	Fe binding site [ion binding]; other site
1132507013032	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1132507013033	EamA-like transporter family; Region: EamA; pfam00892
1132507013034	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1132507013035	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1132507013036	NADP binding site [chemical binding]; other site
1132507013037	Predicted transcriptional regulators [Transcription]; Region: COG1733
1132507013038	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1132507013039	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1132507013040	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1132507013041	active site
1132507013042	metal binding site [ion binding]; metal-binding site
1132507013043	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1132507013044	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1132507013045	active site
1132507013046	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
1132507013047	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1132507013048	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1132507013049	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1132507013050	Domain of unknown function DUF21; Region: DUF21; pfam01595
1132507013051	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1132507013052	Transporter associated domain; Region: CorC_HlyC; smart01091
1132507013053	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1132507013054	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1132507013055	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1132507013056	Surface antigen; Region: Bac_surface_Ag; pfam01103
1132507013057	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1132507013058	Family of unknown function (DUF490); Region: DUF490; pfam04357
1132507013059	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1132507013060	dimerization interface [polypeptide binding]; other site
1132507013061	putative active site pocket [active]
1132507013062	putative catalytic residue [active]
1132507013063	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507013064	D-galactonate transporter; Region: 2A0114; TIGR00893
1132507013065	putative substrate translocation pore; other site
1132507013066	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
1132507013067	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1132507013068	active site
1132507013069	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1132507013070	dimer interface [polypeptide binding]; other site
1132507013071	substrate binding site [chemical binding]; other site
1132507013072	metal binding sites [ion binding]; metal-binding site
1132507013073	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1132507013074	AMP binding site [chemical binding]; other site
1132507013075	metal binding site [ion binding]; metal-binding site
1132507013076	active site
1132507013077	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1132507013078	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1132507013079	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1132507013080	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1132507013081	hypothetical protein; Provisional; Region: PRK05255
1132507013082	peptidase PmbA; Provisional; Region: PRK11040
1132507013083	cytochrome b562; Provisional; Region: PRK15058
1132507013084	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1132507013085	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
1132507013086	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
1132507013087	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1132507013088	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
1132507013089	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
1132507013090	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1132507013091	active site
1132507013092	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1132507013093	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1132507013094	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1132507013095	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1132507013096	HTH domain; Region: HTH_11; pfam08279
1132507013097	Mga helix-turn-helix domain; Region: Mga; pfam05043
1132507013098	PRD domain; Region: PRD; pfam00874
1132507013099	PRD domain; Region: PRD; pfam00874
1132507013100	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1132507013101	active site
1132507013102	P-loop; other site
1132507013103	phosphorylation site [posttranslational modification]
1132507013104	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1132507013105	active site
1132507013106	phosphorylation site [posttranslational modification]
1132507013107	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
1132507013108	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1132507013109	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1132507013110	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1132507013111	FeS/SAM binding site; other site
1132507013112	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1132507013113	ATP cone domain; Region: ATP-cone; pfam03477
1132507013114	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1132507013115	effector binding site; other site
1132507013116	active site
1132507013117	Zn binding site [ion binding]; other site
1132507013118	glycine loop; other site
1132507013119	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1132507013120	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1132507013121	Ca binding site [ion binding]; other site
1132507013122	active site
1132507013123	catalytic site [active]
1132507013124	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1132507013125	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1132507013126	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1132507013127	active site turn [active]
1132507013128	phosphorylation site [posttranslational modification]
1132507013129	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1132507013130	trehalose repressor; Provisional; Region: treR; PRK09492
1132507013131	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507013132	DNA binding site [nucleotide binding]
1132507013133	domain linker motif; other site
1132507013134	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1132507013135	dimerization interface [polypeptide binding]; other site
1132507013136	ligand binding site [chemical binding]; other site
1132507013137	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1132507013138	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1132507013139	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1132507013140	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1132507013141	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1132507013142	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1132507013143	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1132507013144	Transposase; Region: HTH_Tnp_1; cl17663
1132507013145	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1132507013146	homotrimer interaction site [polypeptide binding]; other site
1132507013147	putative active site [active]
1132507013148	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1132507013149	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1132507013150	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1132507013151	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1132507013152	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1132507013153	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1132507013154	Arginine repressor [Transcription]; Region: ArgR; COG1438
1132507013155	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1132507013156	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1132507013157	Predicted membrane protein [Function unknown]; Region: COG1288
1132507013158	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1132507013159	ornithine carbamoyltransferase; Validated; Region: PRK02102
1132507013160	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1132507013161	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1132507013162	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1132507013163	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1132507013164	putative substrate binding site [chemical binding]; other site
1132507013165	nucleotide binding site [chemical binding]; other site
1132507013166	nucleotide binding site [chemical binding]; other site
1132507013167	homodimer interface [polypeptide binding]; other site
1132507013168	arginine deiminase; Provisional; Region: PRK01388
1132507013169	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1132507013170	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1132507013171	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1132507013172	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1132507013173	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
1132507013174	RNase E inhibitor protein; Provisional; Region: PRK11191
1132507013175	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1132507013176	active site
1132507013177	dinuclear metal binding site [ion binding]; other site
1132507013178	dimerization interface [polypeptide binding]; other site
1132507013179	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
1132507013180	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1132507013181	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507013182	Coenzyme A binding pocket [chemical binding]; other site
1132507013183	Predicted membrane protein [Function unknown]; Region: COG4269
1132507013184	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1132507013185	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1132507013186	HIGH motif; other site
1132507013187	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1132507013188	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1132507013189	active site
1132507013190	KMSKS motif; other site
1132507013191	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1132507013192	tRNA binding surface [nucleotide binding]; other site
1132507013193	anticodon binding site; other site
1132507013194	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1132507013195	DNA polymerase III subunit chi; Validated; Region: PRK05728
1132507013196	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1132507013197	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1132507013198	interface (dimer of trimers) [polypeptide binding]; other site
1132507013199	Substrate-binding/catalytic site; other site
1132507013200	Zn-binding sites [ion binding]; other site
1132507013201	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1132507013202	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1132507013203	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1132507013204	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1132507013205	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1132507013206	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1132507013207	DNA binding site [nucleotide binding]
1132507013208	domain linker motif; other site
1132507013209	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1132507013210	putative dimerization interface [polypeptide binding]; other site
1132507013211	putative ligand binding site [chemical binding]; other site
1132507013212	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1132507013213	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1132507013214	gluconate transporter; Region: gntP; TIGR00791
1132507013215	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1132507013216	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507013217	outer membrane fimbrial usher protein SefC; Provisional; Region: PRK15235
1132507013218	PapC N-terminal domain; Region: PapC_N; pfam13954
1132507013219	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1132507013220	PapC C-terminal domain; Region: PapC_C; pfam13953
1132507013221	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1132507013222	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507013223	FaeA-like protein; Region: FaeA; pfam04703
1132507013224	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507013225	DNA binding residues [nucleotide binding]
1132507013226	dimerization interface [polypeptide binding]; other site
1132507013227	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1132507013228	hinge region; other site
1132507013229	alpha helical domain; other site
1132507013230	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1132507013231	SdiA-regulated; Region: SdiA-regulated; cd09971
1132507013232	putative active site [active]
1132507013233	Transposase; Region: HTH_Tnp_1; pfam01527
1132507013234	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1132507013235	Integrase core domain; Region: rve; pfam00665
1132507013236	Integrase core domain; Region: rve_3; pfam13683
1132507013237	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1132507013238	nucleotide binding region [chemical binding]; other site
1132507013239	ATP-binding site [chemical binding]; other site
1132507013240	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
1132507013241	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only]; Region: COG1205
1132507013242	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507013243	ATP binding site [chemical binding]; other site
1132507013244	putative Mg++ binding site [ion binding]; other site
1132507013245	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1132507013246	HNH endonuclease; Region: HNH_2; pfam13391
1132507013247	hypothetical protein; Provisional; Region: PRK12378
1132507013248	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1132507013249	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507013250	S-adenosylmethionine binding site [chemical binding]; other site
1132507013251	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507013252	S-adenosylmethionine binding site [chemical binding]; other site
1132507013253	hypothetical protein; Provisional; Region: PRK13687
1132507013254	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1132507013255	Uncharacterized conserved protein [Function unknown]; Region: COG3439
1132507013256	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1132507013257	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1132507013258	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1132507013259	DNA-binding site [nucleotide binding]; DNA binding site
1132507013260	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1132507013261	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1132507013262	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1132507013263	active site
1132507013264	HIGH motif; other site
1132507013265	dimer interface [polypeptide binding]; other site
1132507013266	KMSKS motif; other site
1132507013267	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1132507013268	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1132507013269	aspartate racemase; Region: asp_race; TIGR00035
1132507013270	cell density-dependent motility repressor; Provisional; Region: PRK10082
1132507013271	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1132507013272	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1132507013273	dimerization interface [polypeptide binding]; other site
1132507013274	isoaspartyl dipeptidase; Provisional; Region: PRK10657
1132507013275	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1132507013276	active site
1132507013277	hypothetical protein; Provisional; Region: PRK10519
1132507013278	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1132507013279	Nucleoside recognition; Region: Gate; pfam07670
1132507013280	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
1132507013281	Predicted membrane protein [Function unknown]; Region: COG2733
1132507013282	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
1132507013283	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1132507013284	putative substrate translocation pore; other site
1132507013285	putative transposase; Provisional; Region: PRK09857
1132507013286	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1132507013287	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
1132507013288	endoribonuclease SymE; Provisional; Region: PRK13605
1132507013289	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
1132507013290	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1132507013291	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1132507013292	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
1132507013293	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
1132507013294	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1132507013295	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1132507013296	ATP binding site [chemical binding]; other site
1132507013297	putative Mg++ binding site [ion binding]; other site
1132507013298	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
1132507013299	Mrr N-terminal domain; Region: Mrr_N; pfam14338
1132507013300	Restriction endonuclease; Region: Mrr_cat; pfam04471
1132507013301	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
1132507013302	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
1132507013303	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1132507013304	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1132507013305	P-loop, Walker A motif; other site
1132507013306	Base recognition motif; other site
1132507013307	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1132507013308	Uncharacterized small protein [Function unknown]; Region: COG2879
1132507013309	carbon starvation protein A; Provisional; Region: PRK15015
1132507013310	Carbon starvation protein CstA; Region: CstA; pfam02554
1132507013311	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1132507013312	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1132507013313	dimer interface [polypeptide binding]; other site
1132507013314	ligand binding site [chemical binding]; other site
1132507013315	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1132507013316	dimerization interface [polypeptide binding]; other site
1132507013317	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1132507013318	dimer interface [polypeptide binding]; other site
1132507013319	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1132507013320	putative CheW interface [polypeptide binding]; other site
1132507013321	phosphoglycerol transferase I; Provisional; Region: PRK03776
1132507013322	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1132507013323	hypothetical protein; Provisional; Region: PRK11667
1132507013324	DNA replication protein DnaC; Validated; Region: PRK07952
1132507013325	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1132507013326	Walker A motif; other site
1132507013327	ATP binding site [chemical binding]; other site
1132507013328	Walker B motif; other site
1132507013329	primosomal protein DnaI; Provisional; Region: PRK02854
1132507013330	hypothetical protein; Provisional; Region: PRK09917
1132507013331	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1132507013332	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1132507013333	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1132507013334	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507013335	DNA binding residues [nucleotide binding]
1132507013336	dimerization interface [polypeptide binding]; other site
1132507013337	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1132507013338	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1132507013339	DNA binding residues [nucleotide binding]
1132507013340	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1132507013341	putative deacylase active site [active]
1132507013342	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1132507013343	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1132507013344	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1132507013345	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1132507013346	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1132507013347	metal binding site [ion binding]; metal-binding site
1132507013348	active site
1132507013349	I-site; other site
1132507013350	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1132507013351	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1132507013352	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1132507013353	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1132507013354	S-adenosylmethionine binding site [chemical binding]; other site
1132507013355	DNA polymerase III subunit psi; Validated; Region: PRK06856
1132507013356	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1132507013357	Coenzyme A binding pocket [chemical binding]; other site
1132507013358	dUMP phosphatase; Provisional; Region: PRK09449
1132507013359	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507013360	motif II; other site
1132507013361	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1132507013362	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1132507013363	G1 box; other site
1132507013364	putative GEF interaction site [polypeptide binding]; other site
1132507013365	GTP/Mg2+ binding site [chemical binding]; other site
1132507013366	Switch I region; other site
1132507013367	G2 box; other site
1132507013368	G3 box; other site
1132507013369	Switch II region; other site
1132507013370	G4 box; other site
1132507013371	G5 box; other site
1132507013372	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1132507013373	periplasmic protein; Provisional; Region: PRK10568
1132507013374	BON domain; Region: BON; pfam04972
1132507013375	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1132507013376	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1132507013377	active site
1132507013378	nucleophile elbow; other site
1132507013379	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1132507013380	active site
1132507013381	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1132507013382	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1132507013383	Pyruvate-formate lyase-activating enzyme [Posttranslational modification, protein turnover, chaperones]; Region: PflA; COG1180
1132507013384	hypothetical protein; Provisional; Region: PRK10977
1132507013385	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1132507013386	intersubunit interface [polypeptide binding]; other site
1132507013387	active site
1132507013388	catalytic residue [active]
1132507013389	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1132507013390	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1132507013391	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1132507013392	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1132507013393	phosphopentomutase; Provisional; Region: PRK05362
1132507013394	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1132507013395	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1132507013396	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1132507013397	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
1132507013398	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1132507013399	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1132507013400	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1132507013401	hypothetical protein; Provisional; Region: PRK11246
1132507013402	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1132507013403	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1132507013404	motif II; other site
1132507013405	DNA repair protein RadA; Region: sms; TIGR00416
1132507013406	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1132507013407	Walker A motif/ATP binding site; other site
1132507013408	ATP binding site [chemical binding]; other site
1132507013409	Walker B motif; other site
1132507013410	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1132507013411	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1132507013412	non-specific DNA binding site [nucleotide binding]; other site
1132507013413	salt bridge; other site
1132507013414	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1132507013415	sequence-specific DNA binding site [nucleotide binding]; other site
1132507013416	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1132507013417	active site
1132507013418	(T/H)XGH motif; other site
1132507013419	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1132507013420	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1132507013421	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1132507013422	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1132507013423	ABC transporter; Region: ABC_tran_2; pfam12848
1132507013424	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1132507013425	lytic murein transglycosylase; Provisional; Region: PRK11619
1132507013426	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1132507013427	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1132507013428	catalytic residue [active]
1132507013429	Trp operon repressor; Provisional; Region: PRK01381
1132507013430	Protein of unknown function DUF84; Region: NTPase_I-T; cl00866
1132507013431	Protein of unknown function DUF84; Region: NTPase_I-T; cl00866
1132507013432	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1132507013433	catalytic core [active]
1132507013434	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1132507013435	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1132507013436	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1132507013437	hypothetical protein; Provisional; Region: PRK10756
1132507013438	CreA protein; Region: CreA; pfam05981
1132507013439	DNA-binding response regulator CreB; Provisional; Region: PRK11083
1132507013440	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507013441	active site
1132507013442	phosphorylation site [posttranslational modification]
1132507013443	intermolecular recognition site; other site
1132507013444	dimerization interface [polypeptide binding]; other site
1132507013445	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507013446	DNA binding site [nucleotide binding]
1132507013447	sensory histidine kinase CreC; Provisional; Region: PRK11100
1132507013448	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1132507013449	dimerization interface [polypeptide binding]; other site
1132507013450	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1132507013451	dimer interface [polypeptide binding]; other site
1132507013452	phosphorylation site [posttranslational modification]
1132507013453	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1132507013454	ATP binding site [chemical binding]; other site
1132507013455	Mg2+ binding site [ion binding]; other site
1132507013456	G-X-G motif; other site
1132507013457	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
1132507013458	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1132507013459	exonuclease subunit SbcD; Provisional; Region: PRK10966
1132507013460	putative fimbrial protein SthD; Provisional; Region: PRK15293
1132507013461	PapC N-terminal domain; Region: PapC_N; pfam13954
1132507013462	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1132507013463	PapC C-terminal domain; Region: PapC_C; pfam13953
1132507013464	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
1132507013465	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1132507013466	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1132507013467	putative fimbrial protein SthA; Provisional; Region: PRK15296
1132507013468	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1132507013469	Helix-turn-helix domain; Region: HTH_36; pfam13730
1132507013470	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1132507013471	two-component response regulator; Provisional; Region: PRK11173
1132507013472	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1132507013473	active site
1132507013474	phosphorylation site [posttranslational modification]
1132507013475	intermolecular recognition site; other site
1132507013476	dimerization interface [polypeptide binding]; other site
1132507013477	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1132507013478	DNA binding site [nucleotide binding]
1132507013479	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1132507013480	putative RNA methyltransferase; Provisional; Region: PRK10433