-- dump date   	20140620_054811
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
527001000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
527001000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
527001000003	putative catalytic residues [active]
527001000004	putative nucleotide binding site [chemical binding]; other site
527001000005	putative aspartate binding site [chemical binding]; other site
527001000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
527001000007	dimer interface [polypeptide binding]; other site
527001000008	putative threonine allosteric regulatory site; other site
527001000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
527001000010	putative threonine allosteric regulatory site; other site
527001000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
527001000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
527001000013	homoserine kinase; Provisional; Region: PRK01212
527001000014	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
527001000015	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
527001000016	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
527001000017	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001000018	catalytic residue [active]
527001000019	hypothetical protein; Validated; Region: PRK02101
527001000020	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
527001000021	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
527001000022	transaldolase-like protein; Provisional; Region: PTZ00411
527001000023	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
527001000024	active site
527001000025	dimer interface [polypeptide binding]; other site
527001000026	catalytic residue [active]
527001000027	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
527001000028	MPT binding site; other site
527001000029	trimer interface [polypeptide binding]; other site
527001000030	hypothetical protein; Provisional; Region: PRK10659
527001000031	hypothetical protein; Provisional; Region: PRK10236
527001000032	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
527001000033	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
527001000034	Protein of unknown function (DUF2541); Region: DUF2541; pfam10807
527001000035	NAD-specific glutamate dehydrogenase; Region: NAD-GH; pfam10712
527001000036	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
527001000037	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
527001000038	nucleotide binding site [chemical binding]; other site
527001000039	chaperone protein DnaJ; Provisional; Region: PRK10767
527001000040	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
527001000041	HSP70 interaction site [polypeptide binding]; other site
527001000042	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
527001000043	substrate binding site [polypeptide binding]; other site
527001000044	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
527001000045	Zn binding sites [ion binding]; other site
527001000046	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
527001000047	dimer interface [polypeptide binding]; other site
527001000048	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001000049	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001000050	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
527001000051	dimerization interface [polypeptide binding]; other site
527001000052	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
527001000053	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
527001000054	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
527001000055	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
527001000056	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
527001000057	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
527001000058	active site
527001000059	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
527001000060	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
527001000061	aromatic chitin/cellulose binding site residues [chemical binding]; other site
527001000062	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
527001000063	Helix-turn-helix domain; Region: HTH_36; pfam13730
527001000064	fimbrial protein BcfA; Provisional; Region: PRK15187
527001000065	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
527001000066	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001000067	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001000068	PapC N-terminal domain; Region: PapC_N; pfam13954
527001000069	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
527001000070	potential frameshift: common BLAST hit: gi|197361234|ref|YP_002140869.1| fimbrial usher
527001000071	fimbrial protein BcfD; Provisional; Region: PRK15189
527001000072	fimbrial protein BcfE; Provisional; Region: PRK15190
527001000073	fimbrial protein BcfF; Provisional; Region: PRK15191
527001000074	fimbrial chaperone BcfG; Provisional; Region: PRK15192
527001000075	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001000076	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001000077	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
527001000078	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
527001000079	catalytic residues [active]
527001000080	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
527001000081	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001000082	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001000083	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
527001000084	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
527001000085	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
527001000086	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
527001000087	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
527001000088	active site
527001000089	metal binding site [ion binding]; metal-binding site
527001000090	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
527001000091	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
527001000092	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
527001000093	Sulfatase; Region: Sulfatase; pfam00884
527001000094	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
527001000095	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001000096	FeS/SAM binding site; other site
527001000097	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
527001000098	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
527001000099	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
527001000100	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
527001000101	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001000102	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
527001000103	putative dimerization interface [polypeptide binding]; other site
527001000104	putative alpha-glucosidase; Provisional; Region: PRK10658
527001000105	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
527001000106	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
527001000107	putative active site [active]
527001000108	putative catalytic site [active]
527001000109	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
527001000110	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
527001000111	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
527001000112	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
527001000113	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
527001000114	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
527001000115	active site
527001000116	Riboflavin kinase; Region: Flavokinase; smart00904
527001000117	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
527001000118	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
527001000119	active site
527001000120	HIGH motif; other site
527001000121	nucleotide binding site [chemical binding]; other site
527001000122	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
527001000123	active site
527001000124	KMSKS motif; other site
527001000125	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
527001000126	tRNA binding surface [nucleotide binding]; other site
527001000127	anticodon binding site; other site
527001000128	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
527001000129	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
527001000130	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
527001000131	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
527001000132	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
527001000133	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
527001000134	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
527001000135	active site
527001000136	tetramer interface [polypeptide binding]; other site
527001000137	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
527001000138	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001000139	active site
527001000140	phosphorylation site [posttranslational modification]
527001000141	intermolecular recognition site; other site
527001000142	dimerization interface [polypeptide binding]; other site
527001000143	Transcriptional regulator; Region: CitT; pfam12431
527001000144	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
527001000145	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
527001000146	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001000147	ATP binding site [chemical binding]; other site
527001000148	Mg2+ binding site [ion binding]; other site
527001000149	G-X-G motif; other site
527001000150	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
527001000151	oxaloacetate decarboxylase; Provisional; Region: PRK14040
527001000152	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
527001000153	active site
527001000154	catalytic residues [active]
527001000155	metal binding site [ion binding]; metal-binding site
527001000156	homodimer binding site [polypeptide binding]; other site
527001000157	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
527001000158	carboxyltransferase (CT) interaction site; other site
527001000159	biotinylation site [posttranslational modification]; other site
527001000160	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
527001000161	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
527001000162	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
527001000163	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
527001000164	putative active site [active]
527001000165	(T/H)XGH motif; other site
527001000166	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
527001000167	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
527001000168	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
527001000169	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
527001000170	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
527001000171	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
527001000172	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
527001000173	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
527001000174	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
527001000175	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
527001000176	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
527001000177	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
527001000178	catalytic site [active]
527001000179	subunit interface [polypeptide binding]; other site
527001000180	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
527001000181	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
527001000182	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
527001000183	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
527001000184	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
527001000185	ATP-grasp domain; Region: ATP-grasp_4; cl17255
527001000186	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
527001000187	IMP binding site; other site
527001000188	dimer interface [polypeptide binding]; other site
527001000189	interdomain contacts; other site
527001000190	partial ornithine binding site; other site
527001000191	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
527001000192	carnitine operon protein CaiE; Provisional; Region: PRK13627
527001000193	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
527001000194	putative trimer interface [polypeptide binding]; other site
527001000195	putative metal binding site [ion binding]; other site
527001000196	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
527001000197	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
527001000198	substrate binding site [chemical binding]; other site
527001000199	oxyanion hole (OAH) forming residues; other site
527001000200	trimer interface [polypeptide binding]; other site
527001000201	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
527001000202	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
527001000203	acyl-activating enzyme (AAE) consensus motif; other site
527001000204	putative AMP binding site [chemical binding]; other site
527001000205	putative active site [active]
527001000206	putative CoA binding site [chemical binding]; other site
527001000207	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
527001000208	CoA-transferase family III; Region: CoA_transf_3; pfam02515
527001000209	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
527001000210	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
527001000211	active site
527001000212	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
527001000213	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
527001000214	Ligand binding site [chemical binding]; other site
527001000215	Electron transfer flavoprotein domain; Region: ETF; pfam01012
527001000216	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
527001000217	Electron transfer flavoprotein domain; Region: ETF; smart00893
527001000218	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
527001000219	putative oxidoreductase FixC; Provisional; Region: PRK10157
527001000220	ferredoxin-like protein FixX; Provisional; Region: PRK15449
527001000221	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001000222	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
527001000223	putative substrate translocation pore; other site
527001000224	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
527001000225	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
527001000226	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
527001000227	Sulfatase; Region: Sulfatase; cl17466
527001000228	Sulfatase; Region: Sulfatase; cl17466
527001000229	Sulfatase; Region: Sulfatase; cl17466
527001000230	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
527001000231	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
527001000232	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
527001000233	TrkA-N domain; Region: TrkA_N; pfam02254
527001000234	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
527001000235	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
527001000236	folate binding site [chemical binding]; other site
527001000237	NADP+ binding site [chemical binding]; other site
527001000238	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
527001000239	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
527001000240	active site
527001000241	metal binding site [ion binding]; metal-binding site
527001000242	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
527001000243	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
527001000244	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
527001000245	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
527001000246	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
527001000247	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
527001000248	SurA N-terminal domain; Region: SurA_N; pfam09312
527001000249	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
527001000250	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
527001000251	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
527001000252	OstA-like protein; Region: OstA; pfam03968
527001000253	Organic solvent tolerance protein; Region: OstA_C; pfam04453
527001000254	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
527001000255	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
527001000256	putative metal binding site [ion binding]; other site
527001000257	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
527001000258	HSP70 interaction site [polypeptide binding]; other site
527001000259	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
527001000260	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
527001000261	active site
527001000262	ATP-dependent helicase HepA; Validated; Region: PRK04914
527001000263	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001000264	ATP binding site [chemical binding]; other site
527001000265	putative Mg++ binding site [ion binding]; other site
527001000266	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001000267	nucleotide binding region [chemical binding]; other site
527001000268	ATP-binding site [chemical binding]; other site
527001000269	DNA polymerase II; Reviewed; Region: PRK05762
527001000270	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
527001000271	active site
527001000272	catalytic site [active]
527001000273	substrate binding site [chemical binding]; other site
527001000274	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
527001000275	active site
527001000276	metal-binding site
527001000277	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cl00630
527001000278	putative active site [active]
527001000279	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001000280	Probable transposase; Region: OrfB_IS605; pfam01385
527001000281	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
527001000282	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
527001000283	Uncharacterized conserved protein [Function unknown]; Region: COG1434
527001000284	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
527001000285	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
527001000286	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
527001000287	intersubunit interface [polypeptide binding]; other site
527001000288	active site
527001000289	Zn2+ binding site [ion binding]; other site
527001000290	L-arabinose isomerase; Provisional; Region: PRK02929
527001000291	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
527001000292	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
527001000293	trimer interface [polypeptide binding]; other site
527001000294	putative substrate binding site [chemical binding]; other site
527001000295	putative metal binding site [ion binding]; other site
527001000296	ribulokinase; Provisional; Region: PRK04123
527001000297	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
527001000298	N- and C-terminal domain interface [polypeptide binding]; other site
527001000299	active site
527001000300	MgATP binding site [chemical binding]; other site
527001000301	catalytic site [active]
527001000302	metal binding site [ion binding]; metal-binding site
527001000303	carbohydrate binding site [chemical binding]; other site
527001000304	homodimer interface [polypeptide binding]; other site
527001000305	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
527001000306	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
527001000307	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001000308	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001000309	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
527001000310	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
527001000311	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
527001000312	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
527001000313	Walker A/P-loop; other site
527001000314	ATP binding site [chemical binding]; other site
527001000315	Q-loop/lid; other site
527001000316	ABC transporter signature motif; other site
527001000317	Walker B; other site
527001000318	D-loop; other site
527001000319	H-loop/switch region; other site
527001000320	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
527001000321	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001000322	dimer interface [polypeptide binding]; other site
527001000323	conserved gate region; other site
527001000324	putative PBP binding loops; other site
527001000325	ABC-ATPase subunit interface; other site
527001000326	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001000327	dimer interface [polypeptide binding]; other site
527001000328	conserved gate region; other site
527001000329	putative PBP binding loops; other site
527001000330	ABC-ATPase subunit interface; other site
527001000331	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
527001000332	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
527001000333	transcriptional regulator SgrR; Provisional; Region: PRK13626
527001000334	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
527001000335	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
527001000336	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
527001000337	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
527001000338	substrate binding site [chemical binding]; other site
527001000339	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
527001000340	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
527001000341	substrate binding site [chemical binding]; other site
527001000342	ligand binding site [chemical binding]; other site
527001000343	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
527001000344	tartrate dehydrogenase; Region: TTC; TIGR02089
527001000345	2-isopropylmalate synthase; Validated; Region: PRK00915
527001000346	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
527001000347	active site
527001000348	catalytic residues [active]
527001000349	metal binding site [ion binding]; metal-binding site
527001000350	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
527001000351	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
527001000352	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001000353	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
527001000354	putative substrate binding pocket [chemical binding]; other site
527001000355	putative dimerization interface [polypeptide binding]; other site
527001000356	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
527001000357	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
527001000358	PYR/PP interface [polypeptide binding]; other site
527001000359	dimer interface [polypeptide binding]; other site
527001000360	TPP binding site [chemical binding]; other site
527001000361	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
527001000362	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
527001000363	TPP-binding site [chemical binding]; other site
527001000364	dimer interface [polypeptide binding]; other site
527001000365	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
527001000366	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
527001000367	putative valine binding site [chemical binding]; other site
527001000368	dimer interface [polypeptide binding]; other site
527001000369	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
527001000370	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
527001000371	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001000372	DNA binding site [nucleotide binding]
527001000373	domain linker motif; other site
527001000374	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
527001000375	dimerization interface [polypeptide binding]; other site
527001000376	ligand binding site [chemical binding]; other site
527001000377	mraZ protein; Region: TIGR00242
527001000378	MraZ protein; Region: MraZ; pfam02381
527001000379	MraZ protein; Region: MraZ; pfam02381
527001000380	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
527001000381	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
527001000382	cell division protein FtsL; Provisional; Region: PRK10772
527001000383	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
527001000384	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
527001000385	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
527001000386	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
527001000387	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
527001000388	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
527001000389	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
527001000390	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
527001000391	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
527001000392	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
527001000393	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
527001000394	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
527001000395	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
527001000396	Mg++ binding site [ion binding]; other site
527001000397	putative catalytic motif [active]
527001000398	putative substrate binding site [chemical binding]; other site
527001000399	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
527001000400	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
527001000401	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
527001000402	cell division protein FtsW; Provisional; Region: PRK10774
527001000403	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
527001000404	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
527001000405	active site
527001000406	homodimer interface [polypeptide binding]; other site
527001000407	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
527001000408	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
527001000409	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
527001000410	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
527001000411	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
527001000412	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
527001000413	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
527001000414	cell division protein FtsQ; Provisional; Region: PRK10775
527001000415	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
527001000416	Cell division protein FtsQ; Region: FtsQ; pfam03799
527001000417	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
527001000418	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
527001000419	Cell division protein FtsA; Region: FtsA; pfam14450
527001000420	cell division protein FtsZ; Validated; Region: PRK09330
527001000421	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
527001000422	nucleotide binding site [chemical binding]; other site
527001000423	SulA interaction site; other site
527001000424	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
527001000425	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
527001000426	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
527001000427	SecA regulator SecM; Provisional; Region: PRK02943
527001000428	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
527001000429	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
527001000430	SEC-C motif; Region: SEC-C; pfam02810
527001000431	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
527001000432	active site
527001000433	8-oxo-dGMP binding site [chemical binding]; other site
527001000434	nudix motif; other site
527001000435	metal binding site [ion binding]; metal-binding site
527001000436	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
527001000437	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
527001000438	active site
527001000439	catalytic tetrad [active]
527001000440	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001000441	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001000442	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
527001000443	putative effector binding pocket; other site
527001000444	putative dimerization interface [polypeptide binding]; other site
527001000445	DNA gyrase inhibitor; Reviewed; Region: PRK00418
527001000446	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
527001000447	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
527001000448	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
527001000449	CoA-binding site [chemical binding]; other site
527001000450	ATP-binding [chemical binding]; other site
527001000451	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
527001000452	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
527001000453	active site
527001000454	type IV pilin biogenesis protein; Provisional; Region: PRK10573
527001000455	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
527001000456	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
527001000457	hypothetical protein; Provisional; Region: PRK10436
527001000458	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
527001000459	Walker A motif; other site
527001000460	ATP binding site [chemical binding]; other site
527001000461	Walker B motif; other site
527001000462	putative major pilin subunit; Provisional; Region: PRK10574
527001000463	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
527001000464	Pilin (bacterial filament); Region: Pilin; pfam00114
527001000465	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
527001000466	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
527001000467	dimerization interface [polypeptide binding]; other site
527001000468	active site
527001000469	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
527001000470	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
527001000471	amidase catalytic site [active]
527001000472	Zn binding residues [ion binding]; other site
527001000473	substrate binding site [chemical binding]; other site
527001000474	regulatory protein AmpE; Provisional; Region: PRK10987
527001000475	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
527001000476	active site
527001000477	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
527001000478	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001000479	putative substrate translocation pore; other site
527001000480	aromatic amino acid transporter; Provisional; Region: PRK10238
527001000481	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
527001000482	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001000483	DNA-binding site [nucleotide binding]; DNA binding site
527001000484	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
527001000485	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
527001000486	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
527001000487	dimer interface [polypeptide binding]; other site
527001000488	TPP-binding site [chemical binding]; other site
527001000489	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
527001000490	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
527001000491	E3 interaction surface; other site
527001000492	lipoyl attachment site [posttranslational modification]; other site
527001000493	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
527001000494	E3 interaction surface; other site
527001000495	lipoyl attachment site [posttranslational modification]; other site
527001000496	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
527001000497	E3 interaction surface; other site
527001000498	lipoyl attachment site [posttranslational modification]; other site
527001000499	e3 binding domain; Region: E3_binding; pfam02817
527001000500	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
527001000501	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
527001000502	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
527001000503	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001000504	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
527001000505	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
527001000506	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
527001000507	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
527001000508	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
527001000509	substrate binding site [chemical binding]; other site
527001000510	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
527001000511	substrate binding site [chemical binding]; other site
527001000512	ligand binding site [chemical binding]; other site
527001000513	hypothetical protein; Provisional; Region: PRK05248
527001000514	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
527001000515	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
527001000516	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
527001000517	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
527001000518	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
527001000519	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
527001000520	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001000521	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
527001000522	spermidine synthase; Provisional; Region: PRK00811
527001000523	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001000524	S-adenosylmethionine binding site [chemical binding]; other site
527001000525	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
527001000526	multicopper oxidase; Provisional; Region: PRK10965
527001000527	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
527001000528	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
527001000529	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
527001000530	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
527001000531	Trp docking motif [polypeptide binding]; other site
527001000532	putative active site [active]
527001000533	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
527001000534	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
527001000535	active site
527001000536	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
527001000537	active site clefts [active]
527001000538	zinc binding site [ion binding]; other site
527001000539	dimer interface [polypeptide binding]; other site
527001000540	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
527001000541	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
527001000542	Walker A/P-loop; other site
527001000543	ATP binding site [chemical binding]; other site
527001000544	Q-loop/lid; other site
527001000545	ABC transporter signature motif; other site
527001000546	Walker B; other site
527001000547	D-loop; other site
527001000548	H-loop/switch region; other site
527001000549	inner membrane transport permease; Provisional; Region: PRK15066
527001000550	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
527001000551	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
527001000552	active pocket/dimerization site; other site
527001000553	active site
527001000554	phosphorylation site [posttranslational modification]
527001000555	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
527001000556	putative active site [active]
527001000557	putative metal binding site [ion binding]; other site
527001000558	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
527001000559	tetramerization interface [polypeptide binding]; other site
527001000560	active site
527001000561	Pantoate-beta-alanine ligase; Region: PanC; cd00560
527001000562	pantoate--beta-alanine ligase; Region: panC; TIGR00018
527001000563	active site
527001000564	ATP-binding site [chemical binding]; other site
527001000565	pantoate-binding site; other site
527001000566	HXXH motif; other site
527001000567	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
527001000568	oligomerization interface [polypeptide binding]; other site
527001000569	active site
527001000570	metal binding site [ion binding]; metal-binding site
527001000571	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
527001000572	putative fimbrial protein StaF; Provisional; Region: PRK15262
527001000573	putative fimbrial protein StaE; Provisional; Region: PRK15263
527001000574	putative fimbrial protein StaD; Provisional; Region: PRK15241
527001000575	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
527001000576	PapC N-terminal domain; Region: PapC_N; pfam13954
527001000577	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
527001000578	PapC C-terminal domain; Region: PapC_C; pfam13953
527001000579	putative chaperone protein EcpD; Provisional; Region: PRK09926
527001000580	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001000581	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001000582	putative fimbrial protein StaA; Provisional; Region: PRK15239
527001000583	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
527001000584	catalytic center binding site [active]
527001000585	ATP binding site [chemical binding]; other site
527001000586	poly(A) polymerase; Region: pcnB; TIGR01942
527001000587	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
527001000588	active site
527001000589	NTP binding site [chemical binding]; other site
527001000590	metal binding triad [ion binding]; metal-binding site
527001000591	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
527001000592	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
527001000593	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
527001000594	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
527001000595	active site
527001000596	nucleotide binding site [chemical binding]; other site
527001000597	HIGH motif; other site
527001000598	KMSKS motif; other site
527001000599	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
527001000600	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
527001000601	2'-5' RNA ligase; Provisional; Region: PRK15124
527001000602	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
527001000603	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
527001000604	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
527001000605	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001000606	ATP binding site [chemical binding]; other site
527001000607	putative Mg++ binding site [ion binding]; other site
527001000608	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001000609	nucleotide binding region [chemical binding]; other site
527001000610	ATP-binding site [chemical binding]; other site
527001000611	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
527001000612	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
527001000613	Transglycosylase; Region: Transgly; pfam00912
527001000614	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
527001000615	potential frameshift: common BLAST hit: gi|194735130|ref|YP_002113220.1| ferrichrome outer membrane transporter
527001000616	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
527001000617	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
527001000618	Walker A/P-loop; other site
527001000619	ATP binding site [chemical binding]; other site
527001000620	Q-loop/lid; other site
527001000621	ABC transporter signature motif; other site
527001000622	Walker B; other site
527001000623	D-loop; other site
527001000624	H-loop/switch region; other site
527001000625	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
527001000626	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
527001000627	siderophore binding site; other site
527001000628	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
527001000629	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
527001000630	ABC-ATPase subunit  interface; other site
527001000631	dimer interface [polypeptide binding]; other site
527001000632	putative PBP binding regions; other site
527001000633	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
527001000634	ABC-ATPase subunit  interface; other site
527001000635	dimer interface [polypeptide binding]; other site
527001000636	putative PBP binding regions; other site
527001000637	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
527001000638	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
527001000639	inhibitor-cofactor binding pocket; inhibition site
527001000640	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001000641	catalytic residue [active]
527001000642	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
527001000643	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
527001000644	Cl- selectivity filter; other site
527001000645	Cl- binding residues [ion binding]; other site
527001000646	pore gating glutamate residue; other site
527001000647	dimer interface [polypeptide binding]; other site
527001000648	H+/Cl- coupling transport residue; other site
527001000649	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
527001000650	hypothetical protein; Provisional; Region: PRK10578
527001000651	UPF0126 domain; Region: UPF0126; pfam03458
527001000652	UPF0126 domain; Region: UPF0126; pfam03458
527001000653	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
527001000654	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
527001000655	cobalamin binding residues [chemical binding]; other site
527001000656	putative BtuC binding residues; other site
527001000657	dimer interface [polypeptide binding]; other site
527001000658	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
527001000659	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
527001000660	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
527001000661	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
527001000662	Zn2+ binding site [ion binding]; other site
527001000663	Mg2+ binding site [ion binding]; other site
527001000664	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
527001000665	serine endoprotease; Provisional; Region: PRK10942
527001000666	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
527001000667	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
527001000668	protein binding site [polypeptide binding]; other site
527001000669	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
527001000670	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
527001000671	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
527001000672	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
527001000673	hypothetical protein; Provisional; Region: PRK13677
527001000674	metabolite-proton symporter; Region: 2A0106; TIGR00883
527001000675	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001000676	putative substrate translocation pore; other site
527001000677	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
527001000678	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
527001000679	trimer interface [polypeptide binding]; other site
527001000680	active site
527001000681	substrate binding site [chemical binding]; other site
527001000682	CoA binding site [chemical binding]; other site
527001000683	PII uridylyl-transferase; Provisional; Region: PRK05007
527001000684	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
527001000685	metal binding triad; other site
527001000686	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
527001000687	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
527001000688	Zn2+ binding site [ion binding]; other site
527001000689	Mg2+ binding site [ion binding]; other site
527001000690	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
527001000691	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
527001000692	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
527001000693	active site
527001000694	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
527001000695	rRNA interaction site [nucleotide binding]; other site
527001000696	S8 interaction site; other site
527001000697	putative laminin-1 binding site; other site
527001000698	elongation factor Ts; Provisional; Region: tsf; PRK09377
527001000699	UBA/TS-N domain; Region: UBA; pfam00627
527001000700	Elongation factor TS; Region: EF_TS; pfam00889
527001000701	Elongation factor TS; Region: EF_TS; pfam00889
527001000702	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
527001000703	putative nucleotide binding site [chemical binding]; other site
527001000704	uridine monophosphate binding site [chemical binding]; other site
527001000705	homohexameric interface [polypeptide binding]; other site
527001000706	ribosome recycling factor; Reviewed; Region: frr; PRK00083
527001000707	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
527001000708	hinge region; other site
527001000709	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
527001000710	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
527001000711	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
527001000712	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
527001000713	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
527001000714	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
527001000715	catalytic residue [active]
527001000716	putative FPP diphosphate  binding site; other site
527001000717	putative FPP binding hydrophobic cleft; other site
527001000718	dimer interface [polypeptide binding]; other site
527001000719	putative IPP diphosphate binding site; other site
527001000720	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
527001000721	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
527001000722	zinc metallopeptidase RseP; Provisional; Region: PRK10779
527001000723	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
527001000724	active site
527001000725	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
527001000726	protein binding site [polypeptide binding]; other site
527001000727	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
527001000728	protein binding site [polypeptide binding]; other site
527001000729	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
527001000730	putative substrate binding region [chemical binding]; other site
527001000731	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
527001000732	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
527001000733	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
527001000734	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
527001000735	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
527001000736	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
527001000737	Surface antigen; Region: Bac_surface_Ag; pfam01103
527001000738	periplasmic chaperone; Provisional; Region: PRK10780
527001000739	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
527001000740	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
527001000741	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
527001000742	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
527001000743	trimer interface [polypeptide binding]; other site
527001000744	active site
527001000745	UDP-GlcNAc binding site [chemical binding]; other site
527001000746	lipid binding site [chemical binding]; lipid-binding site
527001000747	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
527001000748	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
527001000749	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
527001000750	active site
527001000751	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
527001000752	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
527001000753	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
527001000754	RNA/DNA hybrid binding site [nucleotide binding]; other site
527001000755	active site
527001000756	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
527001000757	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
527001000758	putative active site [active]
527001000759	putative PHP Thumb interface [polypeptide binding]; other site
527001000760	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
527001000761	generic binding surface II; other site
527001000762	generic binding surface I; other site
527001000763	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
527001000764	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
527001000765	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001000766	potential frameshift: common BLAST hit: gi|224582081|ref|YP_002635879.1| putative secreted chitinase
527001000767	lysine decarboxylase LdcC; Provisional; Region: PRK15399
527001000768	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
527001000769	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
527001000770	homodimer interface [polypeptide binding]; other site
527001000771	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001000772	catalytic residue [active]
527001000773	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
527001000774	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
527001000775	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
527001000776	putative metal binding site [ion binding]; other site
527001000777	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
527001000778	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
527001000779	Ligand Binding Site [chemical binding]; other site
527001000780	TilS substrate binding domain; Region: TilS; pfam09179
527001000781	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
527001000782	Rho-binding antiterminator; Provisional; Region: PRK11625
527001000783	hypothetical protein; Provisional; Region: PRK04964
527001000784	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
527001000785	hypothetical protein; Provisional; Region: PRK09256
527001000786	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
527001000787	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
527001000788	NlpE N-terminal domain; Region: NlpE; pfam04170
527001000789	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001000790	prolyl-tRNA synthetase; Provisional; Region: PRK09194
527001000791	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
527001000792	dimer interface [polypeptide binding]; other site
527001000793	motif 1; other site
527001000794	active site
527001000795	motif 2; other site
527001000796	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
527001000797	putative deacylase active site [active]
527001000798	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
527001000799	active site
527001000800	motif 3; other site
527001000801	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
527001000802	anticodon binding site; other site
527001000803	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
527001000804	homodimer interaction site [polypeptide binding]; other site
527001000805	cofactor binding site; other site
527001000806	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
527001000807	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
527001000808	lipoprotein, YaeC family; Region: TIGR00363
527001000809	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001000810	dimer interface [polypeptide binding]; other site
527001000811	conserved gate region; other site
527001000812	ABC-ATPase subunit interface; other site
527001000813	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
527001000814	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
527001000815	Walker A/P-loop; other site
527001000816	ATP binding site [chemical binding]; other site
527001000817	Q-loop/lid; other site
527001000818	ABC transporter signature motif; other site
527001000819	Walker B; other site
527001000820	D-loop; other site
527001000821	H-loop/switch region; other site
527001000822	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
527001000823	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
527001000824	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001000825	active site
527001000826	motif I; other site
527001000827	motif II; other site
527001000828	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
527001000829	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
527001000830	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001000831	putative substrate translocation pore; other site
527001000832	lipoprotein; Provisional; Region: PRK10759
527001000833	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
527001000834	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
527001000835	domain interface [polypeptide binding]; other site
527001000836	putative active site [active]
527001000837	catalytic site [active]
527001000838	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
527001000839	domain interface [polypeptide binding]; other site
527001000840	putative active site [active]
527001000841	catalytic site [active]
527001000842	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
527001000843	CoA binding domain; Region: CoA_binding_2; pfam13380
527001000844	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
527001000845	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
527001000846	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
527001000847	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001000848	Coenzyme A binding pocket [chemical binding]; other site
527001000849	Uncharacterized conserved protein [Function unknown]; Region: COG3148
527001000850	thioredoxin 2; Provisional; Region: PRK10996
527001000851	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
527001000852	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
527001000853	catalytic residues [active]
527001000854	putative methyltransferase; Provisional; Region: PRK10864
527001000855	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
527001000856	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
527001000857	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
527001000858	ligand binding site [chemical binding]; other site
527001000859	active site
527001000860	UGI interface [polypeptide binding]; other site
527001000861	catalytic site [active]
527001000862	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
527001000863	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
527001000864	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001000865	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001000866	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
527001000867	dimerization interface [polypeptide binding]; other site
527001000868	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
527001000869	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
527001000870	ATP binding site [chemical binding]; other site
527001000871	Mg++ binding site [ion binding]; other site
527001000872	motif III; other site
527001000873	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001000874	nucleotide binding region [chemical binding]; other site
527001000875	ATP-binding site [chemical binding]; other site
527001000876	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
527001000877	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001000878	S-adenosylmethionine binding site [chemical binding]; other site
527001000879	L-aspartate oxidase; Provisional; Region: PRK09077
527001000880	L-aspartate oxidase; Provisional; Region: PRK06175
527001000881	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
527001000882	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
527001000883	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
527001000884	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
527001000885	DNA binding residues [nucleotide binding]
527001000886	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
527001000887	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
527001000888	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
527001000889	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
527001000890	anti-sigma E factor; Provisional; Region: rseB; PRK09455
527001000891	SoxR reducing system protein RseC; Provisional; Region: PRK10862
527001000892	GTP-binding protein LepA; Provisional; Region: PRK05433
527001000893	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
527001000894	G1 box; other site
527001000895	putative GEF interaction site [polypeptide binding]; other site
527001000896	GTP/Mg2+ binding site [chemical binding]; other site
527001000897	Switch I region; other site
527001000898	G2 box; other site
527001000899	G3 box; other site
527001000900	Switch II region; other site
527001000901	G4 box; other site
527001000902	G5 box; other site
527001000903	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
527001000904	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
527001000905	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
527001000906	signal peptidase I; Provisional; Region: PRK10861
527001000907	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
527001000908	Catalytic site [active]
527001000909	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
527001000910	ribonuclease III; Reviewed; Region: rnc; PRK00102
527001000911	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
527001000912	dimerization interface [polypeptide binding]; other site
527001000913	active site
527001000914	metal binding site [ion binding]; metal-binding site
527001000915	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
527001000916	dsRNA binding site [nucleotide binding]; other site
527001000917	GTPase Era; Reviewed; Region: era; PRK00089
527001000918	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
527001000919	G1 box; other site
527001000920	GTP/Mg2+ binding site [chemical binding]; other site
527001000921	Switch I region; other site
527001000922	G2 box; other site
527001000923	Switch II region; other site
527001000924	G3 box; other site
527001000925	G4 box; other site
527001000926	G5 box; other site
527001000927	KH domain; Region: KH_2; pfam07650
527001000928	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
527001000929	Recombination protein O N terminal; Region: RecO_N; pfam11967
527001000930	Recombination protein O C terminal; Region: RecO_C; pfam02565
527001000931	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
527001000932	active site
527001000933	hydrophilic channel; other site
527001000934	dimerization interface [polypeptide binding]; other site
527001000935	catalytic residues [active]
527001000936	active site lid [active]
527001000937	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
527001000938	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
527001000939	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001000940	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
527001000941	dimerization interface [polypeptide binding]; other site
527001000942	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
527001000943	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001000944	putative substrate translocation pore; other site
527001000945	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
527001000946	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
527001000947	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
527001000948	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
527001000949	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
527001000950	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
527001000951	putative active site [active]
527001000952	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
527001000953	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
527001000954	putative active site [active]
527001000955	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
527001000956	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
527001000957	active site turn [active]
527001000958	phosphorylation site [posttranslational modification]
527001000959	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
527001000960	hypothetical protein; Provisional; Region: PRK11590
527001000961	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
527001000962	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
527001000963	nucleoside/Zn binding site; other site
527001000964	dimer interface [polypeptide binding]; other site
527001000965	catalytic motif [active]
527001000966	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
527001000967	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001000968	substrate binding pocket [chemical binding]; other site
527001000969	membrane-bound complex binding site; other site
527001000970	hinge residues; other site
527001000971	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
527001000972	N-acetyl-D-glucosamine binding site [chemical binding]; other site
527001000973	catalytic residue [active]
527001000974	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
527001000975	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
527001000976	dimerization interface [polypeptide binding]; other site
527001000977	ATP binding site [chemical binding]; other site
527001000978	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
527001000979	dimerization interface [polypeptide binding]; other site
527001000980	ATP binding site [chemical binding]; other site
527001000981	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
527001000982	putative active site [active]
527001000983	catalytic triad [active]
527001000984	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
527001000985	HAMP domain; Region: HAMP; pfam00672
527001000986	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001000987	dimer interface [polypeptide binding]; other site
527001000988	phosphorylation site [posttranslational modification]
527001000989	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001000990	ATP binding site [chemical binding]; other site
527001000991	Mg2+ binding site [ion binding]; other site
527001000992	G-X-G motif; other site
527001000993	hypothetical protein; Provisional; Region: PRK10722
527001000994	response regulator GlrR; Provisional; Region: PRK15115
527001000995	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001000996	active site
527001000997	phosphorylation site [posttranslational modification]
527001000998	intermolecular recognition site; other site
527001000999	dimerization interface [polypeptide binding]; other site
527001001000	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001001001	Walker A motif; other site
527001001002	ATP binding site [chemical binding]; other site
527001001003	Walker B motif; other site
527001001004	arginine finger; other site
527001001005	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
527001001006	Nitrogen regulatory protein P-II; Region: P-II; smart00938
527001001007	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
527001001008	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001001009	putative substrate translocation pore; other site
527001001010	POT family; Region: PTR2; pfam00854
527001001011	lysine decarboxylase CadA; Provisional; Region: PRK15400
527001001012	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
527001001013	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
527001001014	homodimer interface [polypeptide binding]; other site
527001001015	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001001016	catalytic residue [active]
527001001017	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
527001001018	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
527001001019	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
527001001020	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001001021	DNA binding site [nucleotide binding]
527001001022	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
527001001023	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
527001001024	heme-binding site [chemical binding]; other site
527001001025	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
527001001026	FAD binding pocket [chemical binding]; other site
527001001027	FAD binding motif [chemical binding]; other site
527001001028	phosphate binding motif [ion binding]; other site
527001001029	beta-alpha-beta structure motif; other site
527001001030	NAD binding pocket [chemical binding]; other site
527001001031	Heme binding  pocket [chemical binding]; other site
527001001032	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
527001001033	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
527001001034	dimer interface [polypeptide binding]; other site
527001001035	active site
527001001036	glycine-pyridoxal phosphate binding site [chemical binding]; other site
527001001037	folate binding site [chemical binding]; other site
527001001038	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
527001001039	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001001040	putative substrate translocation pore; other site
527001001041	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
527001001042	PRD domain; Region: PRD; pfam00874
527001001043	PRD domain; Region: PRD; pfam00874
527001001044	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
527001001045	potential frameshift: common BLAST hit: gi|194444312|ref|YP_002041813.1| high-affinity nickel-transporter
527001001046	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
527001001047	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
527001001048	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
527001001049	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
527001001050	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
527001001051	FAD binding pocket [chemical binding]; other site
527001001052	FAD binding motif [chemical binding]; other site
527001001053	phosphate binding motif [ion binding]; other site
527001001054	beta-alpha-beta structure motif; other site
527001001055	NAD binding pocket [chemical binding]; other site
527001001056	Iron coordination center [ion binding]; other site
527001001057	sulfite reductase, subunit A; Region: sulfite_red_A; TIGR02910
527001001058	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
527001001059	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
527001001060	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
527001001061	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
527001001062	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
527001001063	active site
527001001064	dimerization interface [polypeptide binding]; other site
527001001065	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
527001001066	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
527001001067	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
527001001068	Rrf2 family protein; Region: rrf2_super; TIGR00738
527001001069	cysteine desulfurase; Provisional; Region: PRK14012
527001001070	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
527001001071	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
527001001072	catalytic residue [active]
527001001073	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
527001001074	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
527001001075	trimerization site [polypeptide binding]; other site
527001001076	active site
527001001077	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
527001001078	co-chaperone HscB; Provisional; Region: hscB; PRK05014
527001001079	DnaJ domain; Region: DnaJ; pfam00226
527001001080	HSP70 interaction site [polypeptide binding]; other site
527001001081	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
527001001082	chaperone protein HscA; Provisional; Region: hscA; PRK05183
527001001083	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
527001001084	nucleotide binding site [chemical binding]; other site
527001001085	putative NEF/HSP70 interaction site [polypeptide binding]; other site
527001001086	SBD interface [polypeptide binding]; other site
527001001087	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
527001001088	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
527001001089	catalytic loop [active]
527001001090	iron binding site [ion binding]; other site
527001001091	hypothetical protein; Provisional; Region: PRK10721
527001001092	aminopeptidase B; Provisional; Region: PRK05015
527001001093	Peptidase; Region: DUF3663; pfam12404
527001001094	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
527001001095	interface (dimer of trimers) [polypeptide binding]; other site
527001001096	Substrate-binding/catalytic site; other site
527001001097	Zn-binding sites [ion binding]; other site
527001001098	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
527001001099	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
527001001100	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
527001001101	active site residue [active]
527001001102	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
527001001103	active site residue [active]
527001001104	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
527001001105	MG2 domain; Region: A2M_N; pfam01835
527001001106	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
527001001107	surface patch; other site
527001001108	thioester region; other site
527001001109	specificity defining residues; other site
527001001110	penicillin-binding protein 1C; Provisional; Region: PRK11240
527001001111	Transglycosylase; Region: Transgly; pfam00912
527001001112	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
527001001113	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
527001001114	potential frameshift: common BLAST hit: gi|198244171|ref|YP_002216594.1| anaerobic dimethyl sulfoxide reductase chain a
527001001115	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
527001001116	4Fe-4S binding domain; Region: Fer4; pfam00037
527001001117	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
527001001118	4Fe-4S binding domain; Region: Fer4; pfam00037
527001001119	hydrogenase 4 subunit H; Validated; Region: PRK08222
527001001120	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
527001001121	active site
527001001122	multimer interface [polypeptide binding]; other site
527001001123	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
527001001124	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001001125	FeS/SAM binding site; other site
527001001126	cytoskeletal protein RodZ; Provisional; Region: PRK10856
527001001127	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001001128	non-specific DNA binding site [nucleotide binding]; other site
527001001129	salt bridge; other site
527001001130	sequence-specific DNA binding site [nucleotide binding]; other site
527001001131	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
527001001132	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
527001001133	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
527001001134	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
527001001135	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
527001001136	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
527001001137	dimer interface [polypeptide binding]; other site
527001001138	motif 1; other site
527001001139	active site
527001001140	motif 2; other site
527001001141	motif 3; other site
527001001142	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
527001001143	anticodon binding site; other site
527001001144	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
527001001145	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
527001001146	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
527001001147	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
527001001148	Trp docking motif [polypeptide binding]; other site
527001001149	GTP-binding protein Der; Reviewed; Region: PRK00093
527001001150	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
527001001151	G1 box; other site
527001001152	GTP/Mg2+ binding site [chemical binding]; other site
527001001153	Switch I region; other site
527001001154	G2 box; other site
527001001155	Switch II region; other site
527001001156	G3 box; other site
527001001157	G4 box; other site
527001001158	G5 box; other site
527001001159	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
527001001160	G1 box; other site
527001001161	GTP/Mg2+ binding site [chemical binding]; other site
527001001162	Switch I region; other site
527001001163	G2 box; other site
527001001164	G3 box; other site
527001001165	Switch II region; other site
527001001166	G4 box; other site
527001001167	G5 box; other site
527001001168	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
527001001169	intimin-like protein SinH; Provisional; Region: PRK15318
527001001170	outer membrane protein RatA; Provisional; Region: PRK15315
527001001171	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
527001001172	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
527001001173	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
527001001174	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
527001001175	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
527001001176	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
527001001177	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
527001001178	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
527001001179	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
527001001180	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
527001001181	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
527001001182	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
527001001183	potential frameshift: common BLAST hit: gi|16765834|ref|NP_461449.1| putative outer membrane protein
527001001184	potential frameshift: common BLAST hit: gi|62181081|ref|YP_217498.1| putative outer membrane protein
527001001185	potential frameshift: common BLAST hit: gi|16765834|ref|NP_461449.1| putative outer membrane protein
527001001186	potential frameshift: common BLAST hit: gi|207857923|ref|YP_002244574.1| host colonisation factor (ShdA)
527001001187	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
527001001188	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
527001001189	generic binding surface II; other site
527001001190	generic binding surface I; other site
527001001191	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
527001001192	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
527001001193	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
527001001194	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
527001001195	active site
527001001196	GMP synthase; Reviewed; Region: guaA; PRK00074
527001001197	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
527001001198	AMP/PPi binding site [chemical binding]; other site
527001001199	candidate oxyanion hole; other site
527001001200	catalytic triad [active]
527001001201	potential glutamine specificity residues [chemical binding]; other site
527001001202	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
527001001203	ATP Binding subdomain [chemical binding]; other site
527001001204	Ligand Binding sites [chemical binding]; other site
527001001205	Dimerization subdomain; other site
527001001206	GIY-YIG domain of uncharacterized proteins from bacteria and their eukaryotic homologs; Region: GIY-YIG_COG3680; cd10440
527001001207	GIY-YIG motif/motif A; other site
527001001208	putative active site [active]
527001001209	putative metal binding site [ion binding]; other site
527001001210	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
527001001211	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
527001001212	MASE1; Region: MASE1; pfam05231
527001001213	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
527001001214	diguanylate cyclase; Region: GGDEF; smart00267
527001001215	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001001216	exopolyphosphatase; Provisional; Region: PRK10854
527001001217	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
527001001218	nucleotide binding site [chemical binding]; other site
527001001219	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
527001001220	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
527001001221	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
527001001222	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
527001001223	putative active site [active]
527001001224	catalytic site [active]
527001001225	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
527001001226	domain interface [polypeptide binding]; other site
527001001227	active site
527001001228	catalytic site [active]
527001001229	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
527001001230	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
527001001231	active site
527001001232	substrate binding site [chemical binding]; other site
527001001233	cosubstrate binding site; other site
527001001234	catalytic site [active]
527001001235	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
527001001236	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
527001001237	dimerization interface [polypeptide binding]; other site
527001001238	putative ATP binding site [chemical binding]; other site
527001001239	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
527001001240	active site
527001001241	uracil transporter; Provisional; Region: PRK10720
527001001242	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
527001001243	DNA replication initiation factor; Provisional; Region: PRK08084
527001001244	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
527001001245	ArsC family; Region: ArsC; pfam03960
527001001246	catalytic residues [active]
527001001247	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
527001001248	Peptidase family M48; Region: Peptidase_M48; cl12018
527001001249	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
527001001250	Domain of unknown function DUF20; Region: UPF0118; pfam01594
527001001251	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
527001001252	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
527001001253	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
527001001254	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
527001001255	fructuronate transporter; Provisional; Region: PRK10034; cl15264
527001001256	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
527001001257	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
527001001258	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
527001001259	catalytic triad [active]
527001001260	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
527001001261	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
527001001262	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
527001001263	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
527001001264	dihydrodipicolinate synthase; Region: dapA; TIGR00674
527001001265	dimer interface [polypeptide binding]; other site
527001001266	active site
527001001267	catalytic residue [active]
527001001268	lipoprotein; Provisional; Region: PRK11679
527001001269	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
527001001270	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
527001001271	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
527001001272	ATP binding site [chemical binding]; other site
527001001273	active site
527001001274	substrate binding site [chemical binding]; other site
527001001275	Predicted metalloprotease [General function prediction only]; Region: COG2321
527001001276	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
527001001277	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
527001001278	Helicase; Region: Helicase_RecD; pfam05127
527001001279	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001001280	Coenzyme A binding pocket [chemical binding]; other site
527001001281	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
527001001282	hypothetical protein; Provisional; Region: PRK13664
527001001283	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
527001001284	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
527001001285	metal binding site [ion binding]; metal-binding site
527001001286	dimer interface [polypeptide binding]; other site
527001001287	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
527001001288	ArsC family; Region: ArsC; pfam03960
527001001289	putative catalytic residues [active]
527001001290	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
527001001291	Protein export membrane protein; Region: SecD_SecF; cl14618
527001001292	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
527001001293	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
527001001294	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001001295	dimerization interface [polypeptide binding]; other site
527001001296	Histidine kinase; Region: HisKA_3; pfam07730
527001001297	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001001298	ATP binding site [chemical binding]; other site
527001001299	Mg2+ binding site [ion binding]; other site
527001001300	G-X-G motif; other site
527001001301	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
527001001302	4Fe-4S binding domain; Region: Fer4; pfam00037
527001001303	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
527001001304	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001001305	putative periplasmic esterase; Provisional; Region: PRK03642
527001001306	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
527001001307	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
527001001308	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
527001001309	dimer interface [polypeptide binding]; other site
527001001310	ADP-ribose binding site [chemical binding]; other site
527001001311	active site
527001001312	nudix motif; other site
527001001313	metal binding site [ion binding]; metal-binding site
527001001314	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
527001001315	transketolase; Reviewed; Region: PRK12753
527001001316	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
527001001317	TPP-binding site [chemical binding]; other site
527001001318	dimer interface [polypeptide binding]; other site
527001001319	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
527001001320	PYR/PP interface [polypeptide binding]; other site
527001001321	dimer interface [polypeptide binding]; other site
527001001322	TPP binding site [chemical binding]; other site
527001001323	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
527001001324	transaldolase-like protein; Provisional; Region: PTZ00411
527001001325	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
527001001326	active site
527001001327	dimer interface [polypeptide binding]; other site
527001001328	catalytic residue [active]
527001001329	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
527001001330	Malic enzyme, N-terminal domain; Region: malic; pfam00390
527001001331	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
527001001332	putative NAD(P) binding site [chemical binding]; other site
527001001333	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
527001001334	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001001335	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
527001001336	putative hexamer interface [polypeptide binding]; other site
527001001337	putative hexagonal pore; other site
527001001338	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
527001001339	G1 box; other site
527001001340	GTP/Mg2+ binding site [chemical binding]; other site
527001001341	G2 box; other site
527001001342	Switch I region; other site
527001001343	G3 box; other site
527001001344	Switch II region; other site
527001001345	G4 box; other site
527001001346	G5 box; other site
527001001347	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
527001001348	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
527001001349	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
527001001350	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
527001001351	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
527001001352	Hexamer/Pentamer interface [polypeptide binding]; other site
527001001353	central pore; other site
527001001354	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
527001001355	putative catalytic cysteine [active]
527001001356	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
527001001357	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
527001001358	nucleotide binding site [chemical binding]; other site
527001001359	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
527001001360	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
527001001361	active site
527001001362	metal binding site [ion binding]; metal-binding site
527001001363	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
527001001364	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
527001001365	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
527001001366	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
527001001367	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
527001001368	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
527001001369	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
527001001370	putative hexamer interface [polypeptide binding]; other site
527001001371	putative hexagonal pore; other site
527001001372	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
527001001373	putative hexamer interface [polypeptide binding]; other site
527001001374	putative hexagonal pore; other site
527001001375	carboxysome structural protein EutK; Provisional; Region: PRK15466
527001001376	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
527001001377	Hexamer interface [polypeptide binding]; other site
527001001378	Hexagonal pore residue; other site
527001001379	transcriptional regulator EutR; Provisional; Region: PRK10130
527001001380	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001001381	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001001382	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
527001001383	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
527001001384	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
527001001385	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
527001001386	active site
527001001387	metal binding site [ion binding]; metal-binding site
527001001388	putative acetyltransferase; Provisional; Region: PRK03624
527001001389	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001001390	Coenzyme A binding pocket [chemical binding]; other site
527001001391	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
527001001392	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
527001001393	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
527001001394	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
527001001395	short chain dehydrogenase; Provisional; Region: PRK08226
527001001396	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
527001001397	NAD binding site [chemical binding]; other site
527001001398	homotetramer interface [polypeptide binding]; other site
527001001399	homodimer interface [polypeptide binding]; other site
527001001400	active site
527001001401	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
527001001402	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
527001001403	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
527001001404	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001001405	dimer interface [polypeptide binding]; other site
527001001406	conserved gate region; other site
527001001407	putative PBP binding loops; other site
527001001408	ABC-ATPase subunit interface; other site
527001001409	sulfate transport protein; Provisional; Region: cysT; CHL00187
527001001410	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001001411	dimer interface [polypeptide binding]; other site
527001001412	conserved gate region; other site
527001001413	putative PBP binding loops; other site
527001001414	ABC-ATPase subunit interface; other site
527001001415	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
527001001416	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
527001001417	Walker A/P-loop; other site
527001001418	ATP binding site [chemical binding]; other site
527001001419	Q-loop/lid; other site
527001001420	ABC transporter signature motif; other site
527001001421	Walker B; other site
527001001422	D-loop; other site
527001001423	H-loop/switch region; other site
527001001424	TOBE-like domain; Region: TOBE_3; pfam12857
527001001425	cysteine synthase B; Region: cysM; TIGR01138
527001001426	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
527001001427	dimer interface [polypeptide binding]; other site
527001001428	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001001429	catalytic residue [active]
527001001430	hypothetical protein; Provisional; Region: PRK10318
527001001431	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
527001001432	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
527001001433	catalytic triad [active]
527001001434	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
527001001435	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001001436	DNA-binding site [nucleotide binding]; DNA binding site
527001001437	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001001438	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001001439	homodimer interface [polypeptide binding]; other site
527001001440	catalytic residue [active]
527001001441	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
527001001442	dimer interface [polypeptide binding]; other site
527001001443	pyridoxamine kinase; Validated; Region: PRK05756
527001001444	pyridoxal binding site [chemical binding]; other site
527001001445	ATP binding site [chemical binding]; other site
527001001446	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
527001001447	HPr interaction site; other site
527001001448	glycerol kinase (GK) interaction site [polypeptide binding]; other site
527001001449	active site
527001001450	phosphorylation site [posttranslational modification]
527001001451	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
527001001452	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
527001001453	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
527001001454	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
527001001455	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
527001001456	dimerization domain swap beta strand [polypeptide binding]; other site
527001001457	regulatory protein interface [polypeptide binding]; other site
527001001458	active site
527001001459	regulatory phosphorylation site [posttranslational modification]; other site
527001001460	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
527001001461	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
527001001462	dimer interface [polypeptide binding]; other site
527001001463	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001001464	catalytic residue [active]
527001001465	putative sulfate transport protein CysZ; Validated; Region: PRK04949
527001001466	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
527001001467	cell division protein ZipA; Provisional; Region: PRK03427
527001001468	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
527001001469	FtsZ protein binding site [polypeptide binding]; other site
527001001470	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
527001001471	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
527001001472	nucleotide binding pocket [chemical binding]; other site
527001001473	K-X-D-G motif; other site
527001001474	catalytic site [active]
527001001475	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
527001001476	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
527001001477	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
527001001478	Dimer interface [polypeptide binding]; other site
527001001479	BRCT sequence motif; other site
527001001480	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
527001001481	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
527001001482	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
527001001483	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001001484	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001001485	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
527001001486	putative dimerization interface [polypeptide binding]; other site
527001001487	hypothetical protein; Provisional; Region: PRK11528
527001001488	purine nucleoside phosphorylase; Provisional; Region: PRK08202
527001001489	nucleoside transporter; Region: 2A0110; TIGR00889
527001001490	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001001491	putative substrate translocation pore; other site
527001001492	XapX domain; Region: XapX; TIGR03510
527001001493	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
527001001494	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001001495	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
527001001496	putative dimerization interface [polypeptide binding]; other site
527001001497	putative substrate binding pocket [chemical binding]; other site
527001001498	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
527001001499	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
527001001500	active site
527001001501	HIGH motif; other site
527001001502	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
527001001503	active site
527001001504	KMSKS motif; other site
527001001505	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
527001001506	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
527001001507	MASE1; Region: MASE1; pfam05231
527001001508	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
527001001509	diguanylate cyclase; Region: GGDEF; smart00267
527001001510	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001001511	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
527001001512	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
527001001513	Nucleoside recognition; Region: Gate; pfam07670
527001001514	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
527001001515	manganese transport protein MntH; Reviewed; Region: PRK00701
527001001516	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
527001001517	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
527001001518	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
527001001519	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
527001001520	active site
527001001521	catalytic tetrad [active]
527001001522	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
527001001523	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
527001001524	dimer interface [polypeptide binding]; other site
527001001525	PYR/PP interface [polypeptide binding]; other site
527001001526	TPP binding site [chemical binding]; other site
527001001527	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
527001001528	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
527001001529	TPP-binding site [chemical binding]; other site
527001001530	dimer interface [polypeptide binding]; other site
527001001531	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
527001001532	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
527001001533	Cl- selectivity filter; other site
527001001534	Cl- binding residues [ion binding]; other site
527001001535	pore gating glutamate residue; other site
527001001536	dimer interface [polypeptide binding]; other site
527001001537	glucokinase; Provisional; Region: glk; PRK00292
527001001538	glucokinase, proteobacterial type; Region: glk; TIGR00749
527001001539	aminotransferase; Validated; Region: PRK08175
527001001540	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001001541	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001001542	homodimer interface [polypeptide binding]; other site
527001001543	catalytic residue [active]
527001001544	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001001545	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
527001001546	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
527001001547	putative acyl-acceptor binding pocket; other site
527001001548	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
527001001549	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
527001001550	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001001551	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001001552	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
527001001553	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
527001001554	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
527001001555	HAMP domain; Region: HAMP; pfam00672
527001001556	dimerization interface [polypeptide binding]; other site
527001001557	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001001558	dimer interface [polypeptide binding]; other site
527001001559	phosphorylation site [posttranslational modification]
527001001560	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001001561	ATP binding site [chemical binding]; other site
527001001562	Mg2+ binding site [ion binding]; other site
527001001563	G-X-G motif; other site
527001001564	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
527001001565	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001001566	active site
527001001567	phosphorylation site [posttranslational modification]
527001001568	intermolecular recognition site; other site
527001001569	dimerization interface [polypeptide binding]; other site
527001001570	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
527001001571	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
527001001572	outer membrane protease; Reviewed; Region: PRK10993
527001001573	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
527001001574	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
527001001575	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
527001001576	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
527001001577	active site
527001001578	Predicted membrane protein [Function unknown]; Region: COG2246
527001001579	GtrA-like protein; Region: GtrA; pfam04138
527001001580	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
527001001581	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
527001001582	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
527001001583	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
527001001584	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
527001001585	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
527001001586	dimer interface [polypeptide binding]; other site
527001001587	active site
527001001588	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
527001001589	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
527001001590	substrate binding site [chemical binding]; other site
527001001591	oxyanion hole (OAH) forming residues; other site
527001001592	trimer interface [polypeptide binding]; other site
527001001593	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
527001001594	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
527001001595	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
527001001596	catalytic core [active]
527001001597	hypothetical protein; Provisional; Region: PRK04946
527001001598	Smr domain; Region: Smr; pfam01713
527001001599	HemK family putative methylases; Region: hemK_fam; TIGR00536
527001001600	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001001601	S-adenosylmethionine binding site [chemical binding]; other site
527001001602	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
527001001603	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
527001001604	Tetramer interface [polypeptide binding]; other site
527001001605	active site
527001001606	FMN-binding site [chemical binding]; other site
527001001607	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
527001001608	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
527001001609	hypothetical protein; Provisional; Region: PRK10621
527001001610	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
527001001611	potential frameshift: common BLAST hit: gi|197361656|ref|YP_002141292.1| putative cytoplasmic protein
527001001612	YfcL protein; Region: YfcL; pfam08891
527001001613	Uncharacterized conserved protein [Function unknown]; Region: COG4121
527001001614	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
527001001615	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
527001001616	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
527001001617	dimer interface [polypeptide binding]; other site
527001001618	active site
527001001619	CAAX protease self-immunity; Region: Abi; pfam02517
527001001620	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
527001001621	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001001622	non-specific DNA binding site [nucleotide binding]; other site
527001001623	salt bridge; other site
527001001624	sequence-specific DNA binding site [nucleotide binding]; other site
527001001625	putative transporter; Provisional; Region: PRK12382
527001001626	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001001627	putative substrate translocation pore; other site
527001001628	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
527001001629	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
527001001630	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
527001001631	ligand binding site [chemical binding]; other site
527001001632	NAD binding site [chemical binding]; other site
527001001633	catalytic site [active]
527001001634	homodimer interface [polypeptide binding]; other site
527001001635	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
527001001636	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
527001001637	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
527001001638	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
527001001639	dimerization interface 3.5A [polypeptide binding]; other site
527001001640	active site
527001001641	hypothetical protein; Provisional; Region: PRK10847
527001001642	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
527001001643	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
527001001644	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
527001001645	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
527001001646	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
527001001647	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
527001001648	cell division protein DedD; Provisional; Region: PRK11633
527001001649	Sporulation related domain; Region: SPOR; pfam05036
527001001650	colicin V production protein; Provisional; Region: PRK10845
527001001651	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
527001001652	amidophosphoribosyltransferase; Provisional; Region: PRK09246
527001001653	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
527001001654	active site
527001001655	tetramer interface [polypeptide binding]; other site
527001001656	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
527001001657	active site
527001001658	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
527001001659	PAS fold; Region: PAS_4; pfam08448
527001001660	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
527001001661	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001001662	Walker A motif; other site
527001001663	ATP binding site [chemical binding]; other site
527001001664	Walker B motif; other site
527001001665	arginine finger; other site
527001001666	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
527001001667	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
527001001668	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
527001001669	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
527001001670	catalytic residue [active]
527001001671	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
527001001672	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
527001001673	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
527001001674	dimer interface [polypeptide binding]; other site
527001001675	active site
527001001676	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
527001001677	substrate binding site [chemical binding]; other site
527001001678	catalytic residue [active]
527001001679	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
527001001680	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
527001001681	Flavoprotein; Region: Flavoprotein; pfam02441
527001001682	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
527001001683	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001001684	substrate binding pocket [chemical binding]; other site
527001001685	membrane-bound complex binding site; other site
527001001686	hinge residues; other site
527001001687	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
527001001688	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001001689	substrate binding pocket [chemical binding]; other site
527001001690	membrane-bound complex binding site; other site
527001001691	hinge residues; other site
527001001692	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
527001001693	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001001694	dimer interface [polypeptide binding]; other site
527001001695	conserved gate region; other site
527001001696	putative PBP binding loops; other site
527001001697	ABC-ATPase subunit interface; other site
527001001698	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
527001001699	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001001700	dimer interface [polypeptide binding]; other site
527001001701	conserved gate region; other site
527001001702	putative PBP binding loops; other site
527001001703	ABC-ATPase subunit interface; other site
527001001704	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
527001001705	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
527001001706	Walker A/P-loop; other site
527001001707	ATP binding site [chemical binding]; other site
527001001708	Q-loop/lid; other site
527001001709	ABC transporter signature motif; other site
527001001710	Walker B; other site
527001001711	D-loop; other site
527001001712	H-loop/switch region; other site
527001001713	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
527001001714	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
527001001715	putative NAD(P) binding site [chemical binding]; other site
527001001716	putative active site [active]
527001001717	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
527001001718	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
527001001719	C-terminal domain interface [polypeptide binding]; other site
527001001720	GSH binding site (G-site) [chemical binding]; other site
527001001721	dimer interface [polypeptide binding]; other site
527001001722	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
527001001723	N-terminal domain interface [polypeptide binding]; other site
527001001724	putative dimer interface [polypeptide binding]; other site
527001001725	active site
527001001726	glutathione S-transferase; Provisional; Region: PRK15113
527001001727	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
527001001728	C-terminal domain interface [polypeptide binding]; other site
527001001729	GSH binding site (G-site) [chemical binding]; other site
527001001730	dimer interface [polypeptide binding]; other site
527001001731	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
527001001732	N-terminal domain interface [polypeptide binding]; other site
527001001733	putative dimer interface [polypeptide binding]; other site
527001001734	putative substrate binding pocket (H-site) [chemical binding]; other site
527001001735	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
527001001736	active site
527001001737	metal binding site [ion binding]; metal-binding site
527001001738	homotetramer interface [polypeptide binding]; other site
527001001739	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
527001001740	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
527001001741	nudix motif; other site
527001001742	Transcriptional regulators [Transcription]; Region: PurR; COG1609
527001001743	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001001744	DNA binding site [nucleotide binding]
527001001745	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
527001001746	putative dimerization interface [polypeptide binding]; other site
527001001747	putative ligand binding site [chemical binding]; other site
527001001748	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
527001001749	active site
527001001750	phosphorylation site [posttranslational modification]
527001001751	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
527001001752	active site
527001001753	P-loop; other site
527001001754	phosphorylation site [posttranslational modification]
527001001755	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
527001001756	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
527001001757	TPP-binding site [chemical binding]; other site
527001001758	dimer interface [polypeptide binding]; other site
527001001759	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
527001001760	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
527001001761	PYR/PP interface [polypeptide binding]; other site
527001001762	dimer interface [polypeptide binding]; other site
527001001763	TPP binding site [chemical binding]; other site
527001001764	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
527001001765	hypothetical protein; Provisional; Region: PRK11588
527001001766	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
527001001767	phosphate acetyltransferase; Reviewed; Region: PRK05632
527001001768	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
527001001769	DRTGG domain; Region: DRTGG; pfam07085
527001001770	phosphate acetyltransferase; Region: pta; TIGR00651
527001001771	propionate/acetate kinase; Provisional; Region: PRK12379
527001001772	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
527001001773	hypothetical protein; Provisional; Region: PRK01816
527001001774	hypothetical protein; Validated; Region: PRK05445
527001001775	putative phosphatase; Provisional; Region: PRK11587
527001001776	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001001777	motif II; other site
527001001778	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
527001001779	transmembrane helices; other site
527001001780	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
527001001781	TrkA-C domain; Region: TrkA_C; pfam02080
527001001782	TrkA-C domain; Region: TrkA_C; pfam02080
527001001783	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
527001001784	5'-nucleotidase; Provisional; Region: PRK03826
527001001785	aminotransferase AlaT; Validated; Region: PRK09265
527001001786	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001001787	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001001788	homodimer interface [polypeptide binding]; other site
527001001789	catalytic residue [active]
527001001790	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
527001001791	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001001792	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
527001001793	putative dimerization interface [polypeptide binding]; other site
527001001794	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
527001001795	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
527001001796	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
527001001797	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
527001001798	NADH dehydrogenase subunit D; Validated; Region: PRK06075
527001001799	NADH dehydrogenase subunit E; Validated; Region: PRK07539
527001001800	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
527001001801	putative dimer interface [polypeptide binding]; other site
527001001802	[2Fe-2S] cluster binding site [ion binding]; other site
527001001803	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
527001001804	SLBB domain; Region: SLBB; pfam10531
527001001805	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
527001001806	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
527001001807	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
527001001808	catalytic loop [active]
527001001809	iron binding site [ion binding]; other site
527001001810	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
527001001811	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
527001001812	[4Fe-4S] binding site [ion binding]; other site
527001001813	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
527001001814	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
527001001815	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
527001001816	4Fe-4S binding domain; Region: Fer4; pfam00037
527001001817	4Fe-4S binding domain; Region: Fer4; pfam00037
527001001818	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
527001001819	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
527001001820	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
527001001821	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
527001001822	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
527001001823	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
527001001824	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
527001001825	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
527001001826	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
527001001827	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
527001001828	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
527001001829	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
527001001830	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001001831	active site
527001001832	phosphorylation site [posttranslational modification]
527001001833	intermolecular recognition site; other site
527001001834	dimerization interface [polypeptide binding]; other site
527001001835	ribonuclease BN; Region: true_RNase_BN; TIGR02649
527001001836	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001001837	Coenzyme A binding pocket [chemical binding]; other site
527001001838	hypothetical protein; Provisional; Region: PRK10404
527001001839	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
527001001840	isochorismate synthases; Region: isochor_syn; TIGR00543
527001001841	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
527001001842	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
527001001843	dimer interface [polypeptide binding]; other site
527001001844	tetramer interface [polypeptide binding]; other site
527001001845	PYR/PP interface [polypeptide binding]; other site
527001001846	TPP binding site [chemical binding]; other site
527001001847	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
527001001848	TPP-binding site; other site
527001001849	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
527001001850	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
527001001851	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
527001001852	substrate binding site [chemical binding]; other site
527001001853	oxyanion hole (OAH) forming residues; other site
527001001854	trimer interface [polypeptide binding]; other site
527001001855	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
527001001856	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
527001001857	active site
527001001858	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
527001001859	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
527001001860	acyl-activating enzyme (AAE) consensus motif; other site
527001001861	putative AMP binding site [chemical binding]; other site
527001001862	putative active site [active]
527001001863	putative CoA binding site [chemical binding]; other site
527001001864	signal transduction protein PmrD; Provisional; Region: PRK15450
527001001865	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
527001001866	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
527001001867	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
527001001868	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
527001001869	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
527001001870	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
527001001871	putative active site [active]
527001001872	putative catalytic site [active]
527001001873	putative Zn binding site [ion binding]; other site
527001001874	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
527001001875	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
527001001876	active site
527001001877	substrate binding site [chemical binding]; other site
527001001878	cosubstrate binding site; other site
527001001879	catalytic site [active]
527001001880	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
527001001881	active site
527001001882	hexamer interface [polypeptide binding]; other site
527001001883	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
527001001884	NAD binding site [chemical binding]; other site
527001001885	substrate binding site [chemical binding]; other site
527001001886	active site
527001001887	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
527001001888	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
527001001889	Ligand binding site; other site
527001001890	Putative Catalytic site; other site
527001001891	DXD motif; other site
527001001892	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
527001001893	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
527001001894	inhibitor-cofactor binding pocket; inhibition site
527001001895	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001001896	catalytic residue [active]
527001001897	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
527001001898	catalytic core [active]
527001001899	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
527001001900	YfaZ precursor; Region: YfaZ; pfam07437
527001001901	hypothetical protein; Provisional; Region: PRK03673
527001001902	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
527001001903	putative MPT binding site; other site
527001001904	Competence-damaged protein; Region: CinA; cl00666
527001001905	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
527001001906	Transcriptional regulator [Transcription]; Region: IclR; COG1414
527001001907	Bacterial transcriptional regulator; Region: IclR; pfam01614
527001001908	L-rhamnonate dehydratase; Provisional; Region: PRK15440
527001001909	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
527001001910	putative active site pocket [active]
527001001911	putative metal binding site [ion binding]; other site
527001001912	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001001913	D-galactonate transporter; Region: 2A0114; TIGR00893
527001001914	putative substrate translocation pore; other site
527001001915	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
527001001916	Competence-damaged protein; Region: CinA; cl00666
527001001917	deubiquitinase SseL; Provisional; Region: PRK14848
527001001918	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
527001001919	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
527001001920	Cysteine-rich domain; Region: CCG; pfam02754
527001001921	Cysteine-rich domain; Region: CCG; pfam02754
527001001922	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
527001001923	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
527001001924	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
527001001925	hydroxyglutarate oxidase; Provisional; Region: PRK11728
527001001926	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
527001001927	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
527001001928	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001001929	putative substrate translocation pore; other site
527001001930	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
527001001931	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
527001001932	active site
527001001933	catalytic site [active]
527001001934	metal binding site [ion binding]; metal-binding site
527001001935	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
527001001936	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001001937	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
527001001938	dimerization interface [polypeptide binding]; other site
527001001939	Major Facilitator Superfamily; Region: MFS_1; pfam07690
527001001940	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001001941	putative substrate translocation pore; other site
527001001942	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
527001001943	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
527001001944	catalytic loop [active]
527001001945	iron binding site [ion binding]; other site
527001001946	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
527001001947	dimer interface [polypeptide binding]; other site
527001001948	putative radical transfer pathway; other site
527001001949	diiron center [ion binding]; other site
527001001950	tyrosyl radical; other site
527001001951	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
527001001952	ATP cone domain; Region: ATP-cone; pfam03477
527001001953	Class I ribonucleotide reductase; Region: RNR_I; cd01679
527001001954	active site
527001001955	dimer interface [polypeptide binding]; other site
527001001956	catalytic residues [active]
527001001957	effector binding site; other site
527001001958	R2 peptide binding site; other site
527001001959	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
527001001960	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001001961	S-adenosylmethionine binding site [chemical binding]; other site
527001001962	Transcriptional regulators [Transcription]; Region: GntR; COG1802
527001001963	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001001964	DNA-binding site [nucleotide binding]; DNA binding site
527001001965	FCD domain; Region: FCD; pfam07729
527001001966	potential frameshift: common BLAST hit: gi|207857693|ref|YP_002244344.1| putative transmembrane transpot protein
527001001967	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
527001001968	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
527001001969	active site pocket [active]
527001001970	DNA gyrase subunit A; Validated; Region: PRK05560
527001001971	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
527001001972	CAP-like domain; other site
527001001973	active site
527001001974	primary dimer interface [polypeptide binding]; other site
527001001975	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
527001001976	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
527001001977	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
527001001978	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
527001001979	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
527001001980	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
527001001981	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001001982	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
527001001983	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001001984	dimer interface [polypeptide binding]; other site
527001001985	phosphorylation site [posttranslational modification]
527001001986	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001001987	ATP binding site [chemical binding]; other site
527001001988	Mg2+ binding site [ion binding]; other site
527001001989	G-X-G motif; other site
527001001990	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
527001001991	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001001992	active site
527001001993	phosphorylation site [posttranslational modification]
527001001994	intermolecular recognition site; other site
527001001995	dimerization interface [polypeptide binding]; other site
527001001996	transcriptional regulator RcsB; Provisional; Region: PRK10840
527001001997	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001001998	active site
527001001999	phosphorylation site [posttranslational modification]
527001002000	intermolecular recognition site; other site
527001002001	dimerization interface [polypeptide binding]; other site
527001002002	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001002003	DNA binding residues [nucleotide binding]
527001002004	dimerization interface [polypeptide binding]; other site
527001002005	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
527001002006	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001002007	ATP binding site [chemical binding]; other site
527001002008	G-X-G motif; other site
527001002009	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
527001002010	putative binding surface; other site
527001002011	active site
527001002012	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
527001002013	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
527001002014	trimer interface [polypeptide binding]; other site
527001002015	eyelet of channel; other site
527001002016	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
527001002017	ApbE family; Region: ApbE; pfam02424
527001002018	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
527001002019	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
527001002020	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001002021	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
527001002022	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
527001002023	DNA binding site [nucleotide binding]
527001002024	active site
527001002025	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
527001002026	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
527001002027	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
527001002028	Walker A/P-loop; other site
527001002029	ATP binding site [chemical binding]; other site
527001002030	Q-loop/lid; other site
527001002031	ABC transporter signature motif; other site
527001002032	Walker B; other site
527001002033	D-loop; other site
527001002034	H-loop/switch region; other site
527001002035	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
527001002036	secondary substrate binding site; other site
527001002037	primary substrate binding site; other site
527001002038	inhibition loop; other site
527001002039	dimerization interface [polypeptide binding]; other site
527001002040	ferredoxin-type protein; Provisional; Region: PRK10194
527001002041	4Fe-4S binding domain; Region: Fer4; cl02805
527001002042	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
527001002043	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
527001002044	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
527001002045	[4Fe-4S] binding site [ion binding]; other site
527001002046	molybdopterin cofactor binding site; other site
527001002047	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
527001002048	molybdopterin cofactor binding site; other site
527001002049	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
527001002050	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
527001002051	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
527001002052	4Fe-4S binding domain; Region: Fer4_5; pfam12801
527001002053	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
527001002054	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
527001002055	cytochrome c-type protein NapC; Provisional; Region: PRK10617
527001002056	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
527001002057	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
527001002058	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001002059	Walker A/P-loop; other site
527001002060	ATP binding site [chemical binding]; other site
527001002061	Q-loop/lid; other site
527001002062	ABC transporter signature motif; other site
527001002063	Walker B; other site
527001002064	D-loop; other site
527001002065	H-loop/switch region; other site
527001002066	heme exporter protein CcmB; Region: ccmB; TIGR01190
527001002067	heme exporter protein CcmC; Region: ccmC; TIGR01191
527001002068	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
527001002069	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
527001002070	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
527001002071	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
527001002072	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
527001002073	catalytic residues [active]
527001002074	central insert; other site
527001002075	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
527001002076	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
527001002077	transcriptional regulator NarP; Provisional; Region: PRK10403
527001002078	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001002079	active site
527001002080	phosphorylation site [posttranslational modification]
527001002081	intermolecular recognition site; other site
527001002082	dimerization interface [polypeptide binding]; other site
527001002083	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001002084	DNA binding residues [nucleotide binding]
527001002085	dimerization interface [polypeptide binding]; other site
527001002086	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
527001002087	DinI-like family; Region: DinI; cl11630
527001002088	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
527001002089	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
527001002090	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
527001002091	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
527001002092	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
527001002093	Leucine-rich repeats; other site
527001002094	Substrate binding site [chemical binding]; other site
527001002095	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
527001002096	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
527001002097	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
527001002098	Sulfatase; Region: Sulfatase; cl17466
527001002099	hypothetical protein; Provisional; Region: PRK13689
527001002100	Nucleoid-associated protein [General function prediction only]; Region: COG3081
527001002101	nucleoid-associated protein NdpA; Validated; Region: PRK00378
527001002102	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
527001002103	5S rRNA interface [nucleotide binding]; other site
527001002104	CTC domain interface [polypeptide binding]; other site
527001002105	L16 interface [polypeptide binding]; other site
527001002106	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
527001002107	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001002108	ATP binding site [chemical binding]; other site
527001002109	putative Mg++ binding site [ion binding]; other site
527001002110	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001002111	nucleotide binding region [chemical binding]; other site
527001002112	ATP-binding site [chemical binding]; other site
527001002113	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
527001002114	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
527001002115	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
527001002116	RNA binding surface [nucleotide binding]; other site
527001002117	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
527001002118	active site
527001002119	uracil binding [chemical binding]; other site
527001002120	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001002121	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
527001002122	putative substrate translocation pore; other site
527001002123	hypothetical protein; Provisional; Region: PRK11835
527001002124	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
527001002125	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001002126	Walker A/P-loop; other site
527001002127	ATP binding site [chemical binding]; other site
527001002128	Q-loop/lid; other site
527001002129	ABC transporter signature motif; other site
527001002130	Walker B; other site
527001002131	D-loop; other site
527001002132	H-loop/switch region; other site
527001002133	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
527001002134	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001002135	Walker A/P-loop; other site
527001002136	ATP binding site [chemical binding]; other site
527001002137	Q-loop/lid; other site
527001002138	ABC transporter signature motif; other site
527001002139	Walker B; other site
527001002140	D-loop; other site
527001002141	H-loop/switch region; other site
527001002142	microcin C ABC transporter permease; Provisional; Region: PRK15021
527001002143	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001002144	dimer interface [polypeptide binding]; other site
527001002145	conserved gate region; other site
527001002146	ABC-ATPase subunit interface; other site
527001002147	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
527001002148	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001002149	dimer interface [polypeptide binding]; other site
527001002150	conserved gate region; other site
527001002151	putative PBP binding loops; other site
527001002152	ABC-ATPase subunit interface; other site
527001002153	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
527001002154	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
527001002155	phage resistance protein; Provisional; Region: PRK10551
527001002156	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
527001002157	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001002158	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
527001002159	NlpC/P60 family; Region: NLPC_P60; pfam00877
527001002160	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
527001002161	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
527001002162	active site
527001002163	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
527001002164	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
527001002165	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
527001002166	elongation factor P; Provisional; Region: PRK04542
527001002167	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
527001002168	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
527001002169	RNA binding site [nucleotide binding]; other site
527001002170	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
527001002171	RNA binding site [nucleotide binding]; other site
527001002172	Flagellin N-methylase; Region: FliB; cl00497
527001002173	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
527001002174	sugar efflux transporter B; Provisional; Region: PRK15011
527001002175	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001002176	putative substrate translocation pore; other site
527001002177	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
527001002178	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
527001002179	active site
527001002180	phosphorylation site [posttranslational modification]
527001002181	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
527001002182	dimerization domain swap beta strand [polypeptide binding]; other site
527001002183	regulatory protein interface [polypeptide binding]; other site
527001002184	active site
527001002185	regulatory phosphorylation site [posttranslational modification]; other site
527001002186	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
527001002187	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
527001002188	putative substrate binding site [chemical binding]; other site
527001002189	putative ATP binding site [chemical binding]; other site
527001002190	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
527001002191	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
527001002192	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
527001002193	active site
527001002194	P-loop; other site
527001002195	phosphorylation site [posttranslational modification]
527001002196	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
527001002197	endonuclease IV; Provisional; Region: PRK01060
527001002198	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
527001002199	AP (apurinic/apyrimidinic) site pocket; other site
527001002200	DNA interaction; other site
527001002201	Metal-binding active site; metal-binding site
527001002202	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
527001002203	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
527001002204	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001002205	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
527001002206	putative dimerization interface [polypeptide binding]; other site
527001002207	lysine transporter; Provisional; Region: PRK10836
527001002208	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
527001002209	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
527001002210	N-terminal plug; other site
527001002211	ligand-binding site [chemical binding]; other site
527001002212	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
527001002213	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
527001002214	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001002215	putative substrate translocation pore; other site
527001002216	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
527001002217	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
527001002218	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001002219	motif II; other site
527001002220	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
527001002221	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
527001002222	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
527001002223	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001002224	non-specific DNA binding site [nucleotide binding]; other site
527001002225	salt bridge; other site
527001002226	sequence-specific DNA binding site [nucleotide binding]; other site
527001002227	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
527001002228	S-formylglutathione hydrolase; Region: PLN02442
527001002229	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
527001002230	GTP cyclohydrolase I; Provisional; Region: PLN03044
527001002231	active site
527001002232	Predicted membrane protein [Function unknown]; Region: COG2311
527001002233	hypothetical protein; Provisional; Region: PRK10835
527001002234	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
527001002235	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001002236	DNA binding site [nucleotide binding]
527001002237	domain linker motif; other site
527001002238	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
527001002239	dimerization interface (closed form) [polypeptide binding]; other site
527001002240	ligand binding site [chemical binding]; other site
527001002241	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
527001002242	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
527001002243	ligand binding site [chemical binding]; other site
527001002244	calcium binding site [ion binding]; other site
527001002245	potential frameshift: common BLAST hit: gi|207857623|ref|YP_002244274.1| galactose/methyl galaxtoside transporter ATP-binding protein
527001002246	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
527001002247	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
527001002248	TM-ABC transporter signature motif; other site
527001002249	potential frameshift: common BLAST hit: gi|197248087|ref|YP_002147158.1| dihydropyrimidine dehydrogenase
527001002250	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
527001002251	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
527001002252	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001002253	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
527001002254	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
527001002255	putative active site [active]
527001002256	cytidine deaminase; Provisional; Region: PRK09027
527001002257	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
527001002258	active site
527001002259	catalytic motif [active]
527001002260	Zn binding site [ion binding]; other site
527001002261	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
527001002262	active site
527001002263	catalytic motif [active]
527001002264	Zn binding site [ion binding]; other site
527001002265	hypothetical protein; Provisional; Region: PRK10711
527001002266	hypothetical protein; Provisional; Region: PRK01821
527001002267	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
527001002268	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001002269	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
527001002270	dimerization interface [polypeptide binding]; other site
527001002271	benzoate transport; Region: 2A0115; TIGR00895
527001002272	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001002273	putative substrate translocation pore; other site
527001002274	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
527001002275	Cupin domain; Region: Cupin_2; pfam07883
527001002276	Cupin domain; Region: Cupin_2; pfam07883
527001002277	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
527001002278	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
527001002279	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
527001002280	maleylacetoacetate isomerase; Region: maiA; TIGR01262
527001002281	C-terminal domain interface [polypeptide binding]; other site
527001002282	GSH binding site (G-site) [chemical binding]; other site
527001002283	putative dimer interface [polypeptide binding]; other site
527001002284	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
527001002285	dimer interface [polypeptide binding]; other site
527001002286	N-terminal domain interface [polypeptide binding]; other site
527001002287	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
527001002288	salicylate hydroxylase; Provisional; Region: PRK08163
527001002289	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
527001002290	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
527001002291	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
527001002292	FMN binding site [chemical binding]; other site
527001002293	active site
527001002294	catalytic residues [active]
527001002295	substrate binding site [chemical binding]; other site
527001002296	potential frameshift: common BLAST hit: gi|207857607|ref|YP_002244258.1| multidrug resistance outer membrane protein MdtQ
527001002297	oxidoreductase; Provisional; Region: PRK12743
527001002298	classical (c) SDRs; Region: SDR_c; cd05233
527001002299	NAD(P) binding site [chemical binding]; other site
527001002300	active site
527001002301	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
527001002302	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
527001002303	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
527001002304	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
527001002305	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
527001002306	D-lactate dehydrogenase; Provisional; Region: PRK11183
527001002307	FAD binding domain; Region: FAD_binding_4; pfam01565
527001002308	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
527001002309	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
527001002310	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
527001002311	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
527001002312	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
527001002313	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001002314	dimer interface [polypeptide binding]; other site
527001002315	conserved gate region; other site
527001002316	ABC-ATPase subunit interface; other site
527001002317	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
527001002318	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
527001002319	Walker A/P-loop; other site
527001002320	ATP binding site [chemical binding]; other site
527001002321	Q-loop/lid; other site
527001002322	ABC transporter signature motif; other site
527001002323	Walker B; other site
527001002324	D-loop; other site
527001002325	H-loop/switch region; other site
527001002326	CBS domain; Region: CBS; pfam00571
527001002327	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
527001002328	putative PBP binding loops; other site
527001002329	ABC-ATPase subunit interface; other site
527001002330	hypothetical protein; Provisional; Region: PRK13681
527001002331	transcriptional regulator MirA; Provisional; Region: PRK15043
527001002332	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
527001002333	DNA binding residues [nucleotide binding]
527001002334	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
527001002335	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
527001002336	GAF domain; Region: GAF; pfam01590
527001002337	Histidine kinase; Region: His_kinase; pfam06580
527001002338	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001002339	ATP binding site [chemical binding]; other site
527001002340	Mg2+ binding site [ion binding]; other site
527001002341	G-X-G motif; other site
527001002342	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
527001002343	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001002344	active site
527001002345	phosphorylation site [posttranslational modification]
527001002346	intermolecular recognition site; other site
527001002347	dimerization interface [polypeptide binding]; other site
527001002348	LytTr DNA-binding domain; Region: LytTR; pfam04397
527001002349	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
527001002350	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
527001002351	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
527001002352	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
527001002353	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
527001002354	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
527001002355	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
527001002356	active site
527001002357	HIGH motif; other site
527001002358	KMSKS motif; other site
527001002359	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
527001002360	tRNA binding surface [nucleotide binding]; other site
527001002361	anticodon binding site; other site
527001002362	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
527001002363	dimer interface [polypeptide binding]; other site
527001002364	putative tRNA-binding site [nucleotide binding]; other site
527001002365	antiporter inner membrane protein; Provisional; Region: PRK11670
527001002366	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
527001002367	Walker A motif; other site
527001002368	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
527001002369	fimbrial chaperone protein; Provisional; Region: PRK15220
527001002370	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
527001002371	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001002372	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001002373	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
527001002374	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
527001002375	Predicted integral membrane protein [Function unknown]; Region: COG5455
527001002376	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
527001002377	substrate binding site [chemical binding]; other site
527001002378	multimerization interface [polypeptide binding]; other site
527001002379	ATP binding site [chemical binding]; other site
527001002380	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
527001002381	dimer interface [polypeptide binding]; other site
527001002382	substrate binding site [chemical binding]; other site
527001002383	ATP binding site [chemical binding]; other site
527001002384	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
527001002385	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001002386	DNA-binding site [nucleotide binding]; DNA binding site
527001002387	UTRA domain; Region: UTRA; pfam07702
527001002388	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
527001002389	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
527001002390	substrate binding site [chemical binding]; other site
527001002391	ATP binding site [chemical binding]; other site
527001002392	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
527001002393	nucleoside transporter; Region: 2A0110; TIGR00889
527001002394	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001002395	putative substrate translocation pore; other site
527001002396	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
527001002397	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
527001002398	putative active site; other site
527001002399	catalytic residue [active]
527001002400	lipid kinase; Reviewed; Region: PRK13054
527001002401	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
527001002402	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
527001002403	putative protease; Provisional; Region: PRK15452
527001002404	Peptidase family U32; Region: Peptidase_U32; pfam01136
527001002405	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
527001002406	Tetratricopeptide repeat; Region: TPR_12; pfam13424
527001002407	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
527001002408	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
527001002409	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
527001002410	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001002411	active site
527001002412	phosphorylation site [posttranslational modification]
527001002413	intermolecular recognition site; other site
527001002414	dimerization interface [polypeptide binding]; other site
527001002415	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001002416	DNA binding site [nucleotide binding]
527001002417	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
527001002418	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001002419	dimerization interface [polypeptide binding]; other site
527001002420	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001002421	dimer interface [polypeptide binding]; other site
527001002422	phosphorylation site [posttranslational modification]
527001002423	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001002424	ATP binding site [chemical binding]; other site
527001002425	Mg2+ binding site [ion binding]; other site
527001002426	G-X-G motif; other site
527001002427	putative transporter; Provisional; Region: PRK10504
527001002428	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001002429	putative substrate translocation pore; other site
527001002430	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
527001002431	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
527001002432	Protein export membrane protein; Region: SecD_SecF; cl14618
527001002433	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
527001002434	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
527001002435	HlyD family secretion protein; Region: HlyD_3; pfam13437
527001002436	putative chaperone; Provisional; Region: PRK11678
527001002437	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
527001002438	nucleotide binding site [chemical binding]; other site
527001002439	putative NEF/HSP70 interaction site [polypeptide binding]; other site
527001002440	SBD interface [polypeptide binding]; other site
527001002441	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
527001002442	AlkA N-terminal domain; Region: AlkA_N; pfam06029
527001002443	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
527001002444	minor groove reading motif; other site
527001002445	helix-hairpin-helix signature motif; other site
527001002446	substrate binding pocket [chemical binding]; other site
527001002447	active site
527001002448	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
527001002449	PAS domain S-box; Region: sensory_box; TIGR00229
527001002450	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
527001002451	putative active site [active]
527001002452	heme pocket [chemical binding]; other site
527001002453	PAS domain S-box; Region: sensory_box; TIGR00229
527001002454	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
527001002455	putative active site [active]
527001002456	heme pocket [chemical binding]; other site
527001002457	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
527001002458	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001002459	metal binding site [ion binding]; metal-binding site
527001002460	active site
527001002461	I-site; other site
527001002462	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001002463	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
527001002464	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
527001002465	ATP-binding site [chemical binding]; other site
527001002466	Sugar specificity; other site
527001002467	Pyrimidine base specificity; other site
527001002468	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
527001002469	trimer interface [polypeptide binding]; other site
527001002470	active site
527001002471	putative assembly protein; Provisional; Region: PRK10833
527001002472	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
527001002473	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
527001002474	FOG: CBS domain [General function prediction only]; Region: COG0517
527001002475	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
527001002476	Transporter associated domain; Region: CorC_HlyC; smart01091
527001002477	polysaccharide export protein Wza; Provisional; Region: PRK15078
527001002478	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
527001002479	Low molecular weight phosphatase family; Region: LMWPc; cd00115
527001002480	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
527001002481	active site
527001002482	tyrosine kinase; Provisional; Region: PRK11519
527001002483	Chain length determinant protein; Region: Wzz; pfam02706
527001002484	Chain length determinant protein; Region: Wzz; cl15801
527001002485	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
527001002486	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
527001002487	putative glycosyl transferase; Provisional; Region: PRK10018
527001002488	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
527001002489	active site
527001002490	putative acyl transferase; Provisional; Region: PRK10191
527001002491	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
527001002492	trimer interface [polypeptide binding]; other site
527001002493	active site
527001002494	substrate binding site [chemical binding]; other site
527001002495	CoA binding site [chemical binding]; other site
527001002496	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
527001002497	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
527001002498	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
527001002499	potential frameshift: common BLAST hit: gi|224583400|ref|YP_002637198.1| putative colanic acid biosynthesis protein
527001002500	putative glycosyl transferase; Provisional; Region: PRK10063
527001002501	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
527001002502	metal-binding site
527001002503	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
527001002504	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
527001002505	putative trimer interface [polypeptide binding]; other site
527001002506	putative active site [active]
527001002507	putative substrate binding site [chemical binding]; other site
527001002508	putative CoA binding site [chemical binding]; other site
527001002509	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
527001002510	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
527001002511	NADP-binding site; other site
527001002512	homotetramer interface [polypeptide binding]; other site
527001002513	substrate binding site [chemical binding]; other site
527001002514	homodimer interface [polypeptide binding]; other site
527001002515	active site
527001002516	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
527001002517	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
527001002518	NADP binding site [chemical binding]; other site
527001002519	active site
527001002520	putative substrate binding site [chemical binding]; other site
527001002521	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
527001002522	active site
527001002523	GDP-Mannose binding site [chemical binding]; other site
527001002524	dimer interface [polypeptide binding]; other site
527001002525	modified nudix motif
527001002526	metal binding site [ion binding]; metal-binding site
527001002527	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
527001002528	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
527001002529	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
527001002530	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
527001002531	Substrate binding site; other site
527001002532	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
527001002533	phosphomannomutase CpsG; Provisional; Region: PRK15414
527001002534	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
527001002535	active site
527001002536	substrate binding site [chemical binding]; other site
527001002537	metal binding site [ion binding]; metal-binding site
527001002538	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
527001002539	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
527001002540	colanic acid exporter; Provisional; Region: PRK10459
527001002541	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
527001002542	potential frameshift: common BLAST hit: gi|197249474|ref|YP_002147059.1| putative pyruvyl transferase
527001002543	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
527001002544	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
527001002545	putative ADP-binding pocket [chemical binding]; other site
527001002546	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
527001002547	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
527001002548	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
527001002549	active site
527001002550	tetramer interface; other site
527001002551	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
527001002552	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
527001002553	NAD binding site [chemical binding]; other site
527001002554	substrate binding site [chemical binding]; other site
527001002555	homodimer interface [polypeptide binding]; other site
527001002556	active site
527001002557	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
527001002558	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
527001002559	NADP binding site [chemical binding]; other site
527001002560	active site
527001002561	putative substrate binding site [chemical binding]; other site
527001002562	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
527001002563	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
527001002564	substrate binding site; other site
527001002565	tetramer interface; other site
527001002566	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
527001002567	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
527001002568	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
527001002569	catalytic loop [active]
527001002570	iron binding site [ion binding]; other site
527001002571	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
527001002572	FAD binding pocket [chemical binding]; other site
527001002573	FAD binding motif [chemical binding]; other site
527001002574	phosphate binding motif [ion binding]; other site
527001002575	beta-alpha-beta structure motif; other site
527001002576	NAD binding pocket [chemical binding]; other site
527001002577	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
527001002578	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
527001002579	substrate binding site; other site
527001002580	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
527001002581	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
527001002582	NAD binding site [chemical binding]; other site
527001002583	homotetramer interface [polypeptide binding]; other site
527001002584	homodimer interface [polypeptide binding]; other site
527001002585	substrate binding site [chemical binding]; other site
527001002586	active site
527001002587	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
527001002588	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
527001002589	inhibitor-cofactor binding pocket; inhibition site
527001002590	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001002591	catalytic residue [active]
527001002592	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
527001002593	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
527001002594	NAD(P) binding site [chemical binding]; other site
527001002595	active site
527001002596	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
527001002597	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
527001002598	NAD binding site [chemical binding]; other site
527001002599	homotetramer interface [polypeptide binding]; other site
527001002600	homodimer interface [polypeptide binding]; other site
527001002601	active site
527001002602	substrate binding site [chemical binding]; other site
527001002603	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
527001002604	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
527001002605	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
527001002606	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
527001002607	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
527001002608	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
527001002609	active site
527001002610	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
527001002611	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
527001002612	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
527001002613	Substrate binding site; other site
527001002614	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
527001002615	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
527001002616	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
527001002617	active site
527001002618	substrate binding site [chemical binding]; other site
527001002619	metal binding site [ion binding]; metal-binding site
527001002620	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
527001002621	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
527001002622	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
527001002623	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
527001002624	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
527001002625	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
527001002626	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
527001002627	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
527001002628	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
527001002629	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
527001002630	chain length determinant protein WzzB; Provisional; Region: PRK15471
527001002631	Chain length determinant protein; Region: Wzz; cl15801
527001002632	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
527001002633	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
527001002634	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
527001002635	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
527001002636	metal binding site [ion binding]; metal-binding site
527001002637	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
527001002638	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
527001002639	substrate binding site [chemical binding]; other site
527001002640	glutamase interaction surface [polypeptide binding]; other site
527001002641	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
527001002642	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
527001002643	catalytic residues [active]
527001002644	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
527001002645	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
527001002646	putative active site [active]
527001002647	oxyanion strand; other site
527001002648	catalytic triad [active]
527001002649	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
527001002650	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001002651	active site
527001002652	motif I; other site
527001002653	motif II; other site
527001002654	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
527001002655	putative active site pocket [active]
527001002656	4-fold oligomerization interface [polypeptide binding]; other site
527001002657	metal binding residues [ion binding]; metal-binding site
527001002658	3-fold/trimer interface [polypeptide binding]; other site
527001002659	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
527001002660	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001002661	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001002662	homodimer interface [polypeptide binding]; other site
527001002663	catalytic residue [active]
527001002664	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
527001002665	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
527001002666	NAD binding site [chemical binding]; other site
527001002667	dimerization interface [polypeptide binding]; other site
527001002668	product binding site; other site
527001002669	substrate binding site [chemical binding]; other site
527001002670	zinc binding site [ion binding]; other site
527001002671	catalytic residues [active]
527001002672	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
527001002673	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
527001002674	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
527001002675	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
527001002676	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
527001002677	putative NAD(P) binding site [chemical binding]; other site
527001002678	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001002679	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
527001002680	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
527001002681	dimerization interface [polypeptide binding]; other site
527001002682	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
527001002683	exonuclease I; Provisional; Region: sbcB; PRK11779
527001002684	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
527001002685	active site
527001002686	catalytic site [active]
527001002687	substrate binding site [chemical binding]; other site
527001002688	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
527001002689	potential frameshift: common BLAST hit: gi|194444317|ref|YP_002041333.1| secreted effector protein
527001002690	thiosulfate reductase PhsA; Provisional; Region: PRK15488
527001002691	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
527001002692	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
527001002693	putative [Fe4-S4] binding site [ion binding]; other site
527001002694	putative molybdopterin cofactor binding site [chemical binding]; other site
527001002695	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
527001002696	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
527001002697	putative molybdopterin cofactor binding site; other site
527001002698	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
527001002699	4Fe-4S binding domain; Region: Fer4; cl02805
527001002700	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
527001002701	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
527001002702	potential frameshift: common BLAST hit: gi|207857497|ref|YP_002244148.1| D-alanyl-D-alanine carboxypeptidase
527001002703	DNA gyrase inhibitor; Provisional; Region: PRK10016
527001002704	Predicted membrane protein [Function unknown]; Region: COG1289
527001002705	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
527001002706	hypothetical protein; Provisional; Region: PRK05423
527001002707	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
527001002708	propionate kinase; Reviewed; Region: PRK12397
527001002709	propionate/acetate kinase; Provisional; Region: PRK12379
527001002710	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
527001002711	G3 box; other site
527001002712	Switch II region; other site
527001002713	GTP/Mg2+ binding site [chemical binding]; other site
527001002714	G4 box; other site
527001002715	G5 box; other site
527001002716	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
527001002717	putative hexamer interface [polypeptide binding]; other site
527001002718	putative hexagonal pore; other site
527001002719	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
527001002720	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
527001002721	putative hexamer interface [polypeptide binding]; other site
527001002722	putative hexagonal pore; other site
527001002723	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
527001002724	putative hexamer interface [polypeptide binding]; other site
527001002725	putative hexagonal pore; other site
527001002726	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
527001002727	SLBB domain; Region: SLBB; pfam10531
527001002728	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
527001002729	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
527001002730	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
527001002731	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
527001002732	putative active site [active]
527001002733	metal binding site [ion binding]; metal-binding site
527001002734	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
527001002735	putative catalytic cysteine [active]
527001002736	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
527001002737	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
527001002738	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cl01889
527001002739	central pore; other site
527001002740	Hexamer/Pentamer interface [polypeptide binding]; other site
527001002741	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
527001002742	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
527001002743	Propanediol utilisation protein PduL; Region: PduL; pfam06130
527001002744	Propanediol utilisation protein PduL; Region: PduL; pfam06130
527001002745	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
527001002746	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
527001002747	putative hexamer interface [polypeptide binding]; other site
527001002748	putative hexagonal pore; other site
527001002749	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
527001002750	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
527001002751	Hexamer interface [polypeptide binding]; other site
527001002752	Putative hexagonal pore residue; other site
527001002753	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
527001002754	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
527001002755	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
527001002756	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
527001002757	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
527001002758	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
527001002759	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
527001002760	alpha-beta subunit interface [polypeptide binding]; other site
527001002761	alpha-gamma subunit interface [polypeptide binding]; other site
527001002762	active site
527001002763	substrate and K+ binding site; other site
527001002764	K+ binding site [ion binding]; other site
527001002765	cobalamin binding site [chemical binding]; other site
527001002766	propanediol utilization protein PduB; Provisional; Region: PRK15415
527001002767	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
527001002768	putative hexamer interface [polypeptide binding]; other site
527001002769	putative hexagonal pore; other site
527001002770	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
527001002771	putative hexamer interface [polypeptide binding]; other site
527001002772	putative hexagonal pore; other site
527001002773	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
527001002774	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
527001002775	Hexamer interface [polypeptide binding]; other site
527001002776	Putative hexagonal pore residue; other site
527001002777	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
527001002778	amphipathic channel; other site
527001002779	Asn-Pro-Ala signature motifs; other site
527001002780	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
527001002781	Sensory domain found in PocR; Region: PocR; pfam10114
527001002782	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001002783	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
527001002784	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001002785	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
527001002786	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
527001002787	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
527001002788	catalytic triad [active]
527001002789	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
527001002790	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
527001002791	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
527001002792	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
527001002793	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
527001002794	active site
527001002795	putative homodimer interface [polypeptide binding]; other site
527001002796	SAM binding site [chemical binding]; other site
527001002797	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
527001002798	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001002799	S-adenosylmethionine binding site [chemical binding]; other site
527001002800	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
527001002801	active site
527001002802	SAM binding site [chemical binding]; other site
527001002803	homodimer interface [polypeptide binding]; other site
527001002804	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
527001002805	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
527001002806	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
527001002807	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
527001002808	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
527001002809	active site
527001002810	SAM binding site [chemical binding]; other site
527001002811	homodimer interface [polypeptide binding]; other site
527001002812	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
527001002813	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
527001002814	Class II Chelatase: a family of ATP-independent monomeric or homodimeric enzymes that catalyze the insertion of metal into protoporphyrin rings. This family includes protoporphyrin IX ferrochelatase (HemH), sirohydrochlorin ferrochelatase (SirB) and the...; Region: Chelatase_Class_II; cl02784
527001002815	active site
527001002816	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
527001002817	Class II Chelatase: a family of ATP-independent monomeric or homodimeric enzymes that catalyze the insertion of metal into protoporphyrin rings. This family includes protoporphyrin IX ferrochelatase (HemH), sirohydrochlorin ferrochelatase (SirB) and the...; Region: Chelatase_Class_II; cl02784
527001002818	active site
527001002819	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
527001002820	active site
527001002821	N-terminal domain interface [polypeptide binding]; other site
527001002822	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
527001002823	active site
527001002824	SAM binding site [chemical binding]; other site
527001002825	homodimer interface [polypeptide binding]; other site
527001002826	potential frameshift: common BLAST hit: gi|197250903|ref|YP_002146980.1| cobalt transport protein CbiM
527001002827	cobalt transport protein CbiN; Provisional; Region: PRK02898
527001002828	cobalt transport protein CbiQ; Provisional; Region: PRK15485
527001002829	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
527001002830	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
527001002831	Walker A/P-loop; other site
527001002832	ATP binding site [chemical binding]; other site
527001002833	Q-loop/lid; other site
527001002834	ABC transporter signature motif; other site
527001002835	Walker B; other site
527001002836	D-loop; other site
527001002837	H-loop/switch region; other site
527001002838	cobyric acid synthase; Provisional; Region: PRK00784
527001002839	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
527001002840	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
527001002841	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
527001002842	catalytic triad [active]
527001002843	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
527001002844	homotrimer interface [polypeptide binding]; other site
527001002845	Walker A motif; other site
527001002846	GTP binding site [chemical binding]; other site
527001002847	Walker B motif; other site
527001002848	cobalamin synthase; Reviewed; Region: cobS; PRK00235
527001002849	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
527001002850	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
527001002851	putative dimer interface [polypeptide binding]; other site
527001002852	active site pocket [active]
527001002853	putative cataytic base [active]
527001002854	L,D-transpeptidase; Provisional; Region: PRK10190
527001002855	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
527001002856	MATE family multidrug exporter; Provisional; Region: PRK10189
527001002857	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
527001002858	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
527001002859	AMP nucleosidase; Provisional; Region: PRK08292
527001002860	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
527001002861	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
527001002862	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
527001002863	MobA/MobL family; Region: MobA_MobL; pfam03389
527001002864	Conjugal transfer protein TraD; Region: TraD; pfam06412
527001002865	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
527001002866	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
527001002867	Restriction endonuclease [Defense mechanisms]; Region: COG3587
527001002868	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001002869	ATP binding site [chemical binding]; other site
527001002870	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
527001002871	DNA methylase; Region: N6_N4_Mtase; pfam01555
527001002872	DNA methylase; Region: N6_N4_Mtase; cl17433
527001002873	integrase; Provisional; Region: PRK09692
527001002874	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
527001002875	active site
527001002876	Int/Topo IB signature motif; other site
527001002877	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
527001002878	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
527001002879	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
527001002880	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
527001002881	Catalytic site [active]
527001002882	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
527001002883	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
527001002884	active site
527001002885	DNA binding site [nucleotide binding]
527001002886	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
527001002887	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
527001002888	DNA-binding site [nucleotide binding]; DNA binding site
527001002889	RNA-binding motif; other site
527001002890	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
527001002891	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
527001002892	trimer interface [polypeptide binding]; other site
527001002893	eyelet of channel; other site
527001002894	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
527001002895	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
527001002896	Zn2+ binding site [ion binding]; other site
527001002897	Mg2+ binding site [ion binding]; other site
527001002898	DNA cytosine methylase; Provisional; Region: PRK10458
527001002899	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
527001002900	cofactor binding site; other site
527001002901	DNA binding site [nucleotide binding]
527001002902	substrate interaction site [chemical binding]; other site
527001002903	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
527001002904	additional DNA contacts [nucleotide binding]; other site
527001002905	mismatch recognition site; other site
527001002906	active site
527001002907	zinc binding site [ion binding]; other site
527001002908	DNA intercalation site [nucleotide binding]; other site
527001002909	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
527001002910	EamA-like transporter family; Region: EamA; pfam00892
527001002911	EamA-like transporter family; Region: EamA; pfam00892
527001002912	Protein of unknown function (DUF808); Region: DUF808; cl01002
527001002913	Protein of unknown function (DUF808); Region: DUF808; cl01002
527001002914	Uncharacterized small protein [Function unknown]; Region: COG5475
527001002915	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
527001002916	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001002917	metal binding site [ion binding]; metal-binding site
527001002918	active site
527001002919	I-site; other site
527001002920	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
527001002921	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001002922	active site
527001002923	motif I; other site
527001002924	motif II; other site
527001002925	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
527001002926	hypothetical protein; Provisional; Region: PRK10708
527001002927	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
527001002928	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001002929	DNA binding residues [nucleotide binding]
527001002930	dimerization interface [polypeptide binding]; other site
527001002931	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
527001002932	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
527001002933	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
527001002934	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
527001002935	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
527001002936	flagellar motor switch protein; Validated; Region: fliN; PRK05698
527001002937	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
527001002938	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
527001002939	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
527001002940	flagellar hook-length control protein; Provisional; Region: PRK10118
527001002941	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
527001002942	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
527001002943	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
527001002944	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
527001002945	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
527001002946	Walker A motif/ATP binding site; other site
527001002947	Walker B motif; other site
527001002948	flagellar assembly protein H; Validated; Region: fliH; PRK05687
527001002949	Flagellar assembly protein FliH; Region: FliH; pfam02108
527001002950	flagellar motor switch protein FliG; Region: fliG; TIGR00207
527001002951	FliG C-terminal domain; Region: FliG_C; pfam01706
527001002952	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
527001002953	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
527001002954	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
527001002955	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
527001002956	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
527001002957	CPxP  motif; other site
527001002958	putative inner membrane protein; Provisional; Region: PRK11099
527001002959	Sulphur transport; Region: Sulf_transp; pfam04143
527001002960	lipoprotein; Provisional; Region: PRK10397
527001002961	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
527001002962	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
527001002963	active site
527001002964	Na/Ca binding site [ion binding]; other site
527001002965	catalytic site [active]
527001002966	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
527001002967	flagellar protein FliS; Validated; Region: fliS; PRK05685
527001002968	flagellar capping protein; Reviewed; Region: fliD; PRK08032
527001002969	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
527001002970	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
527001002971	flagellin; Validated; Region: PRK08026
527001002972	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
527001002973	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
527001002974	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
527001002975	potential frameshift: common BLAST hit: gi|194450789|ref|YP_002046007.1| lysine-N-methylase
527001002976	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
527001002977	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
527001002978	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
527001002979	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
527001002980	DNA binding residues [nucleotide binding]
527001002981	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
527001002982	cystine transporter subunit; Provisional; Region: PRK11260
527001002983	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001002984	substrate binding pocket [chemical binding]; other site
527001002985	membrane-bound complex binding site; other site
527001002986	hinge residues; other site
527001002987	D-cysteine desulfhydrase; Validated; Region: PRK03910
527001002988	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
527001002989	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001002990	catalytic residue [active]
527001002991	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
527001002992	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001002993	dimer interface [polypeptide binding]; other site
527001002994	conserved gate region; other site
527001002995	putative PBP binding loops; other site
527001002996	ABC-ATPase subunit interface; other site
527001002997	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
527001002998	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
527001002999	Walker A/P-loop; other site
527001003000	ATP binding site [chemical binding]; other site
527001003001	Q-loop/lid; other site
527001003002	ABC transporter signature motif; other site
527001003003	Walker B; other site
527001003004	D-loop; other site
527001003005	H-loop/switch region; other site
527001003006	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
527001003007	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
527001003008	Autoinducer binding domain; Region: Autoind_bind; pfam03472
527001003009	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001003010	DNA binding residues [nucleotide binding]
527001003011	dimerization interface [polypeptide binding]; other site
527001003012	hypothetical protein; Provisional; Region: PRK10613
527001003013	response regulator; Provisional; Region: PRK09483
527001003014	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001003015	active site
527001003016	phosphorylation site [posttranslational modification]
527001003017	intermolecular recognition site; other site
527001003018	dimerization interface [polypeptide binding]; other site
527001003019	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001003020	DNA binding residues [nucleotide binding]
527001003021	dimerization interface [polypeptide binding]; other site
527001003022	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
527001003023	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
527001003024	GIY-YIG motif/motif A; other site
527001003025	active site
527001003026	catalytic site [active]
527001003027	putative DNA binding site [nucleotide binding]; other site
527001003028	metal binding site [ion binding]; metal-binding site
527001003029	UvrB/uvrC motif; Region: UVR; pfam02151
527001003030	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
527001003031	Helix-hairpin-helix motif; Region: HHH; pfam00633
527001003032	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
527001003033	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
527001003034	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
527001003035	NlpC/P60 family; Region: NLPC_P60; cl17555
527001003036	hypothetical protein; Provisional; Region: PRK10396
527001003037	yecA family protein; Region: ygfB_yecA; TIGR02292
527001003038	SEC-C motif; Region: SEC-C; pfam02810
527001003039	tyrosine transporter TyrP; Provisional; Region: PRK15132
527001003040	aromatic amino acid transport protein; Region: araaP; TIGR00837
527001003041	probable metal-binding protein; Region: matur_matur; TIGR03853
527001003042	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
527001003043	Ferritin-like domain; Region: Ferritin; pfam00210
527001003044	ferroxidase diiron center [ion binding]; other site
527001003045	YecR-like lipoprotein; Region: YecR; pfam13992
527001003046	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
527001003047	Ferritin-like domain; Region: Ferritin; pfam00210
527001003048	ferroxidase diiron center [ion binding]; other site
527001003049	DJ-1 family protein; Region: not_thiJ; TIGR01383
527001003050	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
527001003051	conserved cys residue [active]
527001003052	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
527001003053	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
527001003054	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
527001003055	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
527001003056	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
527001003057	active site
527001003058	homotetramer interface [polypeptide binding]; other site
527001003059	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
527001003060	Ligand Binding Site [chemical binding]; other site
527001003061	transcriptional activator FlhD; Provisional; Region: PRK02909
527001003062	transcriptional activator FlhC; Provisional; Region: PRK12722
527001003063	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
527001003064	flagellar motor protein MotA; Validated; Region: PRK09110
527001003065	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
527001003066	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
527001003067	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
527001003068	ligand binding site [chemical binding]; other site
527001003069	chemotaxis protein CheA; Provisional; Region: PRK10547
527001003070	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
527001003071	putative binding surface; other site
527001003072	active site
527001003073	CheY binding; Region: CheY-binding; pfam09078
527001003074	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
527001003075	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001003076	ATP binding site [chemical binding]; other site
527001003077	Mg2+ binding site [ion binding]; other site
527001003078	G-X-G motif; other site
527001003079	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
527001003080	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
527001003081	putative CheA interaction surface; other site
527001003082	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
527001003083	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
527001003084	dimer interface [polypeptide binding]; other site
527001003085	ligand binding site [chemical binding]; other site
527001003086	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001003087	dimerization interface [polypeptide binding]; other site
527001003088	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
527001003089	dimer interface [polypeptide binding]; other site
527001003090	putative CheW interface [polypeptide binding]; other site
527001003091	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
527001003092	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
527001003093	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001003094	S-adenosylmethionine binding site [chemical binding]; other site
527001003095	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
527001003096	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001003097	active site
527001003098	phosphorylation site [posttranslational modification]
527001003099	intermolecular recognition site; other site
527001003100	dimerization interface [polypeptide binding]; other site
527001003101	CheB methylesterase; Region: CheB_methylest; pfam01339
527001003102	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
527001003103	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001003104	active site
527001003105	phosphorylation site [posttranslational modification]
527001003106	intermolecular recognition site; other site
527001003107	dimerization interface [polypeptide binding]; other site
527001003108	chemotaxis regulator CheZ; Provisional; Region: PRK11166
527001003109	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
527001003110	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
527001003111	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
527001003112	FHIPEP family; Region: FHIPEP; pfam00771
527001003113	Flagellar protein FlhE; Region: FlhE; pfam06366
527001003114	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
527001003115	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
527001003116	arginyl-tRNA synthetase; Region: argS; TIGR00456
527001003117	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
527001003118	active site
527001003119	HIGH motif; other site
527001003120	KMSK motif region; other site
527001003121	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
527001003122	tRNA binding surface [nucleotide binding]; other site
527001003123	anticodon binding site; other site
527001003124	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
527001003125	putative metal binding site [ion binding]; other site
527001003126	copper homeostasis protein CutC; Provisional; Region: PRK11572
527001003127	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001003128	S-adenosylmethionine binding site [chemical binding]; other site
527001003129	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001003130	S-adenosylmethionine binding site [chemical binding]; other site
527001003131	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
527001003132	hypothetical protein; Provisional; Region: PRK10302
527001003133	Isochorismatase family; Region: Isochorismatase; pfam00857
527001003134	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
527001003135	catalytic triad [active]
527001003136	conserved cis-peptide bond; other site
527001003137	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
527001003138	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
527001003139	dimer interface [polypeptide binding]; other site
527001003140	anticodon binding site; other site
527001003141	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
527001003142	homodimer interface [polypeptide binding]; other site
527001003143	motif 1; other site
527001003144	active site
527001003145	motif 2; other site
527001003146	GAD domain; Region: GAD; pfam02938
527001003147	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
527001003148	active site
527001003149	motif 3; other site
527001003150	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
527001003151	nudix motif; other site
527001003152	hypothetical protein; Validated; Region: PRK00110
527001003153	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
527001003154	active site
527001003155	putative DNA-binding cleft [nucleotide binding]; other site
527001003156	dimer interface [polypeptide binding]; other site
527001003157	hypothetical protein; Provisional; Region: PRK11470
527001003158	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
527001003159	RuvA N terminal domain; Region: RuvA_N; pfam01330
527001003160	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
527001003161	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
527001003162	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001003163	Walker A motif; other site
527001003164	ATP binding site [chemical binding]; other site
527001003165	Walker B motif; other site
527001003166	arginine finger; other site
527001003167	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
527001003168	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
527001003169	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
527001003170	ABC-ATPase subunit  interface; other site
527001003171	dimer interface [polypeptide binding]; other site
527001003172	putative PBP binding regions; other site
527001003173	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
527001003174	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
527001003175	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
527001003176	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
527001003177	metal binding site [ion binding]; metal-binding site
527001003178	putative peptidase; Provisional; Region: PRK11649
527001003179	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
527001003180	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
527001003181	Peptidase family M23; Region: Peptidase_M23; pfam01551
527001003182	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
527001003183	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
527001003184	putative acyl-acceptor binding pocket; other site
527001003185	pyruvate kinase; Provisional; Region: PRK05826
527001003186	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
527001003187	domain interfaces; other site
527001003188	active site
527001003189	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
527001003190	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
527001003191	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
527001003192	putative active site [active]
527001003193	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
527001003194	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
527001003195	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
527001003196	phosphogluconate dehydratase; Validated; Region: PRK09054
527001003197	6-phosphogluconate dehydratase; Region: edd; TIGR01196
527001003198	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
527001003199	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
527001003200	active site
527001003201	intersubunit interface [polypeptide binding]; other site
527001003202	catalytic residue [active]
527001003203	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
527001003204	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
527001003205	ATP-grasp domain; Region: ATP-grasp; pfam02222
527001003206	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
527001003207	hypothetical protein; Provisional; Region: PRK13680
527001003208	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
527001003209	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
527001003210	putative metal binding site [ion binding]; other site
527001003211	protease 2; Provisional; Region: PRK10115
527001003212	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
527001003213	exodeoxyribonuclease X; Provisional; Region: PRK07983
527001003214	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
527001003215	active site
527001003216	catalytic site [active]
527001003217	substrate binding site [chemical binding]; other site
527001003218	Predicted amidohydrolase [General function prediction only]; Region: COG0388
527001003219	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
527001003220	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
527001003221	hypothetical protein; Provisional; Region: PRK10301
527001003222	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
527001003223	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
527001003224	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
527001003225	DNA binding site [nucleotide binding]
527001003226	active site
527001003227	Int/Topo IB signature motif; other site
527001003228	potential frameshift: common BLAST hit: gi|205352425|ref|YP_002226226.1| recombination and repair protein RecT
527001003229	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
527001003230	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
527001003231	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001003232	metal binding site [ion binding]; metal-binding site
527001003233	active site
527001003234	I-site; other site
527001003235	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
527001003236	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
527001003237	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
527001003238	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
527001003239	EamA-like transporter family; Region: EamA; pfam00892
527001003240	EamA-like transporter family; Region: EamA; pfam00892
527001003241	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
527001003242	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
527001003243	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
527001003244	MULE transposase domain; Region: MULE; pfam10551
527001003245	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001003246	Coenzyme A binding pocket [chemical binding]; other site
527001003247	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
527001003248	SopE GEF domain; Region: SopE_GEF; pfam07487
527001003249	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
527001003250	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
527001003251	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
527001003252	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
527001003253	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
527001003254	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
527001003255	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
527001003256	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
527001003257	mce related protein; Region: MCE; pfam02470
527001003258	mce related protein; Region: MCE; pfam02470
527001003259	mce related protein; Region: MCE; pfam02470
527001003260	mce related protein; Region: MCE; pfam02470
527001003261	mce related protein; Region: MCE; pfam02470
527001003262	mce related protein; Region: MCE; pfam02470
527001003263	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
527001003264	Paraquat-inducible protein A; Region: PqiA; pfam04403
527001003265	Paraquat-inducible protein A; Region: PqiA; pfam04403
527001003266	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
527001003267	GAF domain; Region: GAF_2; pfam13185
527001003268	ProP expression regulator; Provisional; Region: PRK04950
527001003269	ProQ/FINO family; Region: ProQ; pfam04352
527001003270	carboxy-terminal protease; Provisional; Region: PRK11186
527001003271	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
527001003272	protein binding site [polypeptide binding]; other site
527001003273	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
527001003274	Catalytic dyad [active]
527001003275	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
527001003276	heat shock protein HtpX; Provisional; Region: PRK05457
527001003277	potential frameshift: common BLAST hit: gi|16765184|ref|NP_460799.1| putative transport protein
527001003278	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
527001003279	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
527001003280	dimerization interface [polypeptide binding]; other site
527001003281	putative Zn2+ binding site [ion binding]; other site
527001003282	putative DNA binding site [nucleotide binding]; other site
527001003283	Bacterial transcriptional regulator; Region: IclR; pfam01614
527001003284	YobH-like protein; Region: YobH; pfam13996
527001003285	PhoPQ regulatory protein; Provisional; Region: PRK10299
527001003286	YebO-like protein; Region: YebO; pfam13974
527001003287	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
527001003288	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
527001003289	DNA-binding site [nucleotide binding]; DNA binding site
527001003290	RNA-binding motif; other site
527001003291	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
527001003292	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
527001003293	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
527001003294	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
527001003295	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001003296	S-adenosylmethionine binding site [chemical binding]; other site
527001003297	hypothetical protein; Provisional; Region: PRK11469
527001003298	Domain of unknown function DUF; Region: DUF204; pfam02659
527001003299	Domain of unknown function DUF; Region: DUF204; pfam02659
527001003300	hypothetical protein; Provisional; Region: PRK02913
527001003301	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
527001003302	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
527001003303	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
527001003304	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
527001003305	active pocket/dimerization site; other site
527001003306	active site
527001003307	phosphorylation site [posttranslational modification]
527001003308	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
527001003309	active site
527001003310	phosphorylation site [posttranslational modification]
527001003311	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
527001003312	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
527001003313	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
527001003314	Transporter associated domain; Region: CorC_HlyC; smart01091
527001003315	phage resistance protein; Provisional; Region: PRK10551
527001003316	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
527001003317	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001003318	L-serine deaminase; Provisional; Region: PRK15023
527001003319	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
527001003320	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
527001003321	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
527001003322	putative active site [active]
527001003323	putative CoA binding site [chemical binding]; other site
527001003324	nudix motif; other site
527001003325	metal binding site [ion binding]; metal-binding site
527001003326	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
527001003327	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
527001003328	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
527001003329	hypothetical protein; Provisional; Region: PRK05114
527001003330	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
527001003331	homotrimer interaction site [polypeptide binding]; other site
527001003332	putative active site [active]
527001003333	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
527001003334	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
527001003335	DEAD_2; Region: DEAD_2; pfam06733
527001003336	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
527001003337	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
527001003338	Glycoprotease family; Region: Peptidase_M22; pfam00814
527001003339	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
527001003340	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
527001003341	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
527001003342	acyl-activating enzyme (AAE) consensus motif; other site
527001003343	putative AMP binding site [chemical binding]; other site
527001003344	putative active site [active]
527001003345	putative CoA binding site [chemical binding]; other site
527001003346	ribonuclease D; Provisional; Region: PRK10829
527001003347	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
527001003348	catalytic site [active]
527001003349	putative active site [active]
527001003350	putative substrate binding site [chemical binding]; other site
527001003351	HRDC domain; Region: HRDC; cl02578
527001003352	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
527001003353	cell division inhibitor MinD; Provisional; Region: PRK10818
527001003354	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
527001003355	Switch I; other site
527001003356	Switch II; other site
527001003357	septum formation inhibitor; Reviewed; Region: minC; PRK03511
527001003358	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
527001003359	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
527001003360	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
527001003361	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
527001003362	hypothetical protein; Provisional; Region: PRK10691
527001003363	hypothetical protein; Provisional; Region: PRK05170
527001003364	GnsA/GnsB family; Region: GnsAB; pfam08178
527001003365	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
527001003366	disulfide bond formation protein B; Provisional; Region: PRK01749
527001003367	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
527001003368	transmembrane helices; other site
527001003369	fatty acid metabolism regulator; Provisional; Region: PRK04984
527001003370	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001003371	DNA-binding site [nucleotide binding]; DNA binding site
527001003372	FadR C-terminal domain; Region: FadR_C; pfam07840
527001003373	SpoVR family protein; Provisional; Region: PRK11767
527001003374	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
527001003375	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
527001003376	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
527001003377	alanine racemase; Reviewed; Region: dadX; PRK03646
527001003378	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
527001003379	active site
527001003380	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
527001003381	substrate binding site [chemical binding]; other site
527001003382	catalytic residues [active]
527001003383	dimer interface [polypeptide binding]; other site
527001003384	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
527001003385	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
527001003386	TrkA-C domain; Region: TrkA_C; pfam02080
527001003387	Transporter associated domain; Region: CorC_HlyC; smart01091
527001003388	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
527001003389	dimer interface [polypeptide binding]; other site
527001003390	catalytic triad [active]
527001003391	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
527001003392	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
527001003393	N-acetyl-D-glucosamine binding site [chemical binding]; other site
527001003394	catalytic residue [active]
527001003395	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
527001003396	Flagellar regulator YcgR; Region: YcgR; pfam07317
527001003397	PilZ domain; Region: PilZ; pfam07238
527001003398	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
527001003399	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
527001003400	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
527001003401	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
527001003402	NAD(P) binding site [chemical binding]; other site
527001003403	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
527001003404	potential frameshift: common BLAST hit: gi|197250984|ref|YP_002146231.1| cytochrome D ubiquinol oxidase, subunit II
527001003405	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
527001003406	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
527001003407	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
527001003408	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
527001003409	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
527001003410	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
527001003411	putative substrate-binding site; other site
527001003412	nickel binding site [ion binding]; other site
527001003413	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
527001003414	hydrogenase 1 large subunit; Provisional; Region: PRK10170
527001003415	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
527001003416	potential frameshift: common BLAST hit: gi|194737959|ref|YP_002114821.1| hydrogenase-1 small chain
527001003417	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
527001003418	Protein of unknown function (DUF4427); Region: DUF4427; pfam14468
527001003419	GTP-binding protein YchF; Reviewed; Region: PRK09601
527001003420	YchF GTPase; Region: YchF; cd01900
527001003421	G1 box; other site
527001003422	GTP/Mg2+ binding site [chemical binding]; other site
527001003423	Switch I region; other site
527001003424	G2 box; other site
527001003425	Switch II region; other site
527001003426	G3 box; other site
527001003427	G4 box; other site
527001003428	G5 box; other site
527001003429	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
527001003430	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
527001003431	putative active site [active]
527001003432	catalytic residue [active]
527001003433	hypothetical protein; Provisional; Region: PRK10692
527001003434	putative transporter; Provisional; Region: PRK11660
527001003435	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
527001003436	Sulfate transporter family; Region: Sulfate_transp; pfam00916
527001003437	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
527001003438	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
527001003439	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
527001003440	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
527001003441	active site
527001003442	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
527001003443	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
527001003444	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
527001003445	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
527001003446	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
527001003447	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
527001003448	tRNA; other site
527001003449	putative tRNA binding site [nucleotide binding]; other site
527001003450	putative NADP binding site [chemical binding]; other site
527001003451	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
527001003452	peptide chain release factor 1; Validated; Region: prfA; PRK00591
527001003453	This domain is found in peptide chain release factors; Region: PCRF; smart00937
527001003454	RF-1 domain; Region: RF-1; pfam00472
527001003455	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
527001003456	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001003457	hypothetical protein; Provisional; Region: PRK10278
527001003458	hypothetical protein; Provisional; Region: PRK10941
527001003459	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
527001003460	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
527001003461	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
527001003462	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001003463	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
527001003464	subtilase cytotoxin subunit B; Provisional; Region: PRK15266
527001003465	pertussis toxin-like subunit ArtA; Provisional; Region: PRK15272
527001003466	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
527001003467	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
527001003468	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
527001003469	Protein of unknown function (DUF1353); Region: DUF1353; pfam07087
527001003470	CdtB, the catalytic DNase I-like subunit of cytolethal distending toxin (CDT) protein; Region: CdtB; cd09081
527001003471	putative catalytic site [active]
527001003472	CdtC interface [polypeptide binding]; other site
527001003473	heterotrimer interface [polypeptide binding]; other site
527001003474	CdtA interface [polypeptide binding]; other site
527001003475	putative metal binding site [ion binding]; other site
527001003476	putative phosphate binding site [ion binding]; other site
527001003477	putative transposase OrfB; Reviewed; Region: PHA02517
527001003478	DinI-like family; Region: DinI; pfam06183
527001003479	Ricin-type beta-trefoil; Region: RICIN; smart00458
527001003480	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
527001003481	putative sugar binding sites [chemical binding]; other site
527001003482	Q-X-W motif; other site
527001003483	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
527001003484	DNA-binding site [nucleotide binding]; DNA binding site
527001003485	RNA-binding motif; other site
527001003486	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
527001003487	lysozyme inhibitor; Provisional; Region: PRK13791
527001003488	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
527001003489	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
527001003490	putative dimer interface [polypeptide binding]; other site
527001003491	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
527001003492	BNR repeat-like domain; Region: BNR_2; pfam13088
527001003493	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
527001003494	TRL-like protein family; Region: TRL; pfam13146
527001003495	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
527001003496	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
527001003497	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
527001003498	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001003499	dimer interface [polypeptide binding]; other site
527001003500	conserved gate region; other site
527001003501	ABC-ATPase subunit interface; other site
527001003502	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
527001003503	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001003504	dimer interface [polypeptide binding]; other site
527001003505	conserved gate region; other site
527001003506	putative PBP binding loops; other site
527001003507	ABC-ATPase subunit interface; other site
527001003508	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001003509	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
527001003510	Walker A/P-loop; other site
527001003511	ATP binding site [chemical binding]; other site
527001003512	Q-loop/lid; other site
527001003513	ABC transporter signature motif; other site
527001003514	Walker B; other site
527001003515	D-loop; other site
527001003516	H-loop/switch region; other site
527001003517	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001003518	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
527001003519	Walker A/P-loop; other site
527001003520	ATP binding site [chemical binding]; other site
527001003521	Q-loop/lid; other site
527001003522	ABC transporter signature motif; other site
527001003523	Walker B; other site
527001003524	D-loop; other site
527001003525	H-loop/switch region; other site
527001003526	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
527001003527	Mechanosensitive ion channel; Region: MS_channel; pfam00924
527001003528	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
527001003529	dimerization interface [polypeptide binding]; other site
527001003530	zinc/cadmium-binding protein; Provisional; Region: PRK10306
527001003531	aminoglycoside resistance protein; Provisional; Region: PRK13746
527001003532	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
527001003533	active site
527001003534	NTP binding site [chemical binding]; other site
527001003535	metal binding triad [ion binding]; metal-binding site
527001003536	antibiotic binding site [chemical binding]; other site
527001003537	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
527001003538	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001003539	DNA binding residues [nucleotide binding]
527001003540	transcriptional regulator MirA; Provisional; Region: PRK15043
527001003541	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
527001003542	DNA binding residues [nucleotide binding]
527001003543	dimer interface [polypeptide binding]; other site
527001003544	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
527001003545	chorismate mutase; Provisional; Region: PRK08055
527001003546	leucine export protein LeuE; Provisional; Region: PRK10958
527001003547	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
527001003548	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
527001003549	hypothetical protein; Provisional; Region: PRK10457
527001003550	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001003551	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
527001003552	murein hydrolase B; Provisional; Region: PRK10760; cl17906
527001003553	Domain of unknown function (DUF333); Region: DUF333; pfam03891
527001003554	Uncharacterized conserved protein [Function unknown]; Region: COG3189
527001003555	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
527001003556	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001003557	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
527001003558	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001003559	Predicted membrane protein [Function unknown]; Region: COG2707
527001003560	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
527001003561	putative deacylase active site [active]
527001003562	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
527001003563	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001003564	metal binding site [ion binding]; metal-binding site
527001003565	active site
527001003566	I-site; other site
527001003567	hypothetical protein; Provisional; Region: PRK05325
527001003568	PrkA family serine protein kinase; Provisional; Region: PRK15455
527001003569	AAA ATPase domain; Region: AAA_16; pfam13191
527001003570	Walker A motif; other site
527001003571	ATP binding site [chemical binding]; other site
527001003572	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
527001003573	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
527001003574	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
527001003575	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
527001003576	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
527001003577	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
527001003578	active site
527001003579	catalytic tetrad [active]
527001003580	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
527001003581	active site
527001003582	phosphate binding residues; other site
527001003583	catalytic residues [active]
527001003584	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
527001003585	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
527001003586	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
527001003587	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
527001003588	methionine sulfoxide reductase B; Provisional; Region: PRK00222
527001003589	SelR domain; Region: SelR; pfam01641
527001003590	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
527001003591	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
527001003592	Isochorismatase family; Region: Isochorismatase; pfam00857
527001003593	catalytic triad [active]
527001003594	metal binding site [ion binding]; metal-binding site
527001003595	conserved cis-peptide bond; other site
527001003596	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
527001003597	active site
527001003598	homodimer interface [polypeptide binding]; other site
527001003599	protease 4; Provisional; Region: PRK10949
527001003600	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
527001003601	tandem repeat interface [polypeptide binding]; other site
527001003602	oligomer interface [polypeptide binding]; other site
527001003603	active site residues [active]
527001003604	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
527001003605	tandem repeat interface [polypeptide binding]; other site
527001003606	oligomer interface [polypeptide binding]; other site
527001003607	active site residues [active]
527001003608	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
527001003609	putative FMN binding site [chemical binding]; other site
527001003610	selenophosphate synthetase; Provisional; Region: PRK00943
527001003611	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
527001003612	dimerization interface [polypeptide binding]; other site
527001003613	putative ATP binding site [chemical binding]; other site
527001003614	DNA topoisomerase III; Provisional; Region: PRK07726
527001003615	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
527001003616	active site
527001003617	putative interdomain interaction site [polypeptide binding]; other site
527001003618	putative metal-binding site [ion binding]; other site
527001003619	putative nucleotide binding site [chemical binding]; other site
527001003620	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
527001003621	domain I; other site
527001003622	DNA binding groove [nucleotide binding]
527001003623	phosphate binding site [ion binding]; other site
527001003624	domain II; other site
527001003625	domain III; other site
527001003626	nucleotide binding site [chemical binding]; other site
527001003627	catalytic site [active]
527001003628	domain IV; other site
527001003629	glutamate dehydrogenase; Provisional; Region: PRK09414
527001003630	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
527001003631	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
527001003632	NAD(P) binding site [chemical binding]; other site
527001003633	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
527001003634	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
527001003635	active site
527001003636	8-oxo-dGMP binding site [chemical binding]; other site
527001003637	nudix motif; other site
527001003638	metal binding site [ion binding]; metal-binding site
527001003639	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
527001003640	putative catalytic site [active]
527001003641	putative phosphate binding site [ion binding]; other site
527001003642	active site
527001003643	metal binding site A [ion binding]; metal-binding site
527001003644	DNA binding site [nucleotide binding]
527001003645	putative AP binding site [nucleotide binding]; other site
527001003646	putative metal binding site B [ion binding]; other site
527001003647	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
527001003648	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
527001003649	inhibitor-cofactor binding pocket; inhibition site
527001003650	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001003651	catalytic residue [active]
527001003652	potential frameshift: common BLAST hit: gi|16760591|ref|NP_456208.1| arginine succinyltransferase
527001003653	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
527001003654	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
527001003655	NAD(P) binding site [chemical binding]; other site
527001003656	catalytic residues [active]
527001003657	succinylarginine dihydrolase; Provisional; Region: PRK13281
527001003658	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
527001003659	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
527001003660	putative active site [active]
527001003661	Zn binding site [ion binding]; other site
527001003662	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
527001003663	dimer interface [polypeptide binding]; other site
527001003664	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
527001003665	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
527001003666	GIY-YIG motif/motif A; other site
527001003667	active site
527001003668	catalytic site [active]
527001003669	putative DNA binding site [nucleotide binding]; other site
527001003670	metal binding site [ion binding]; metal-binding site
527001003671	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
527001003672	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
527001003673	homodimer interface [polypeptide binding]; other site
527001003674	NAD binding pocket [chemical binding]; other site
527001003675	ATP binding pocket [chemical binding]; other site
527001003676	Mg binding site [ion binding]; other site
527001003677	active-site loop [active]
527001003678	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
527001003679	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
527001003680	active site
527001003681	P-loop; other site
527001003682	phosphorylation site [posttranslational modification]
527001003683	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
527001003684	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
527001003685	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
527001003686	methionine cluster; other site
527001003687	active site
527001003688	phosphorylation site [posttranslational modification]
527001003689	metal binding site [ion binding]; metal-binding site
527001003690	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
527001003691	Cupin domain; Region: Cupin_2; pfam07883
527001003692	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001003693	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
527001003694	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
527001003695	NAD binding site [chemical binding]; other site
527001003696	sugar binding site [chemical binding]; other site
527001003697	divalent metal binding site [ion binding]; other site
527001003698	tetramer (dimer of dimers) interface [polypeptide binding]; other site
527001003699	dimer interface [polypeptide binding]; other site
527001003700	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
527001003701	putative active site [active]
527001003702	YdjC motif; other site
527001003703	Mg binding site [ion binding]; other site
527001003704	putative homodimer interface [polypeptide binding]; other site
527001003705	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001003706	hydroperoxidase II; Provisional; Region: katE; PRK11249
527001003707	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
527001003708	tetramer interface [polypeptide binding]; other site
527001003709	heme binding pocket [chemical binding]; other site
527001003710	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
527001003711	domain interactions; other site
527001003712	cell division modulator; Provisional; Region: PRK10113
527001003713	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
527001003714	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
527001003715	inner membrane protein; Provisional; Region: PRK11648
527001003716	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
527001003717	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
527001003718	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001003719	motif II; other site
527001003720	YniB-like protein; Region: YniB; pfam14002
527001003721	Phosphotransferase enzyme family; Region: APH; pfam01636
527001003722	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
527001003723	active site
527001003724	ATP binding site [chemical binding]; other site
527001003725	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
527001003726	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
527001003727	6-phosphofructokinase 2; Provisional; Region: PRK10294
527001003728	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
527001003729	putative substrate binding site [chemical binding]; other site
527001003730	putative ATP binding site [chemical binding]; other site
527001003731	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
527001003732	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
527001003733	potential frameshift: common BLAST hit: gi|194443189|ref|YP_002040589.1| DNA/RNA non-specific endonuclease
527001003734	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
527001003735	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
527001003736	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
527001003737	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
527001003738	active site
527001003739	dimer interface [polypeptide binding]; other site
527001003740	motif 1; other site
527001003741	motif 2; other site
527001003742	motif 3; other site
527001003743	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
527001003744	anticodon binding site; other site
527001003745	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
527001003746	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
527001003747	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
527001003748	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
527001003749	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
527001003750	23S rRNA binding site [nucleotide binding]; other site
527001003751	L21 binding site [polypeptide binding]; other site
527001003752	L13 binding site [polypeptide binding]; other site
527001003753	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
527001003754	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
527001003755	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
527001003756	dimer interface [polypeptide binding]; other site
527001003757	motif 1; other site
527001003758	active site
527001003759	motif 2; other site
527001003760	motif 3; other site
527001003761	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
527001003762	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
527001003763	putative tRNA-binding site [nucleotide binding]; other site
527001003764	B3/4 domain; Region: B3_4; pfam03483
527001003765	tRNA synthetase B5 domain; Region: B5; smart00874
527001003766	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
527001003767	dimer interface [polypeptide binding]; other site
527001003768	motif 1; other site
527001003769	motif 3; other site
527001003770	motif 2; other site
527001003771	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
527001003772	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
527001003773	IHF dimer interface [polypeptide binding]; other site
527001003774	IHF - DNA interface [nucleotide binding]; other site
527001003775	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
527001003776	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
527001003777	ABC-ATPase subunit  interface; other site
527001003778	dimer interface [polypeptide binding]; other site
527001003779	putative PBP binding regions; other site
527001003780	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
527001003781	catalytic residues [active]
527001003782	dimer interface [polypeptide binding]; other site
527001003783	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
527001003784	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
527001003785	Walker A/P-loop; other site
527001003786	ATP binding site [chemical binding]; other site
527001003787	Q-loop/lid; other site
527001003788	ABC transporter signature motif; other site
527001003789	Walker B; other site
527001003790	D-loop; other site
527001003791	H-loop/switch region; other site
527001003792	NlpC/P60 family; Region: NLPC_P60; pfam00877
527001003793	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
527001003794	Uncharacterized conserved protein [Function unknown]; Region: COG0397
527001003795	hypothetical protein; Validated; Region: PRK00029
527001003796	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
527001003797	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
527001003798	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
527001003799	PEP synthetase regulatory protein; Provisional; Region: PRK05339
527001003800	phosphoenolpyruvate synthase; Validated; Region: PRK06464
527001003801	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
527001003802	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
527001003803	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
527001003804	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
527001003805	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
527001003806	active site
527001003807	catalytic residue [active]
527001003808	dimer interface [polypeptide binding]; other site
527001003809	putative inner membrane protein; Provisional; Region: PRK10983
527001003810	Domain of unknown function DUF20; Region: UPF0118; pfam01594
527001003811	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
527001003812	FAD binding domain; Region: FAD_binding_4; pfam01565
527001003813	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
527001003814	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
527001003815	CoenzymeA binding site [chemical binding]; other site
527001003816	subunit interaction site [polypeptide binding]; other site
527001003817	PHB binding site; other site
527001003818	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
527001003819	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
527001003820	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
527001003821	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
527001003822	putative ABC transporter; Region: ycf24; CHL00085
527001003823	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
527001003824	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
527001003825	Walker A/P-loop; other site
527001003826	ATP binding site [chemical binding]; other site
527001003827	Q-loop/lid; other site
527001003828	ABC transporter signature motif; other site
527001003829	Walker B; other site
527001003830	D-loop; other site
527001003831	H-loop/switch region; other site
527001003832	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
527001003833	FeS assembly protein SufD; Region: sufD; TIGR01981
527001003834	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
527001003835	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
527001003836	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
527001003837	catalytic residue [active]
527001003838	cysteine desufuration protein SufE; Provisional; Region: PRK09296
527001003839	potential frameshift: common BLAST hit: gi|198245212|ref|YP_002215752.1| ErfK/YbiS/YcfS/YnhG family protein
527001003840	murein lipoprotein; Provisional; Region: PRK15396
527001003841	murein lipoprotein; Provisional; Region: PRK15396
527001003842	pyruvate kinase; Provisional; Region: PRK09206
527001003843	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
527001003844	domain interfaces; other site
527001003845	active site
527001003846	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
527001003847	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
527001003848	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
527001003849	potential frameshift: common BLAST hit: gi|197251345|ref|YP_002146658.1| putative regulatory protein, DeoR family
527001003850	tetrathionate reductase subunit A; Provisional; Region: PRK14991
527001003851	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
527001003852	putative [Fe4-S4] binding site [ion binding]; other site
527001003853	putative molybdopterin cofactor binding site [chemical binding]; other site
527001003854	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
527001003855	putative molybdopterin cofactor binding site; other site
527001003856	tetrathionate reductase subunit C; Provisional; Region: PRK14992
527001003857	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
527001003858	tetrathionate reductase subunit B; Provisional; Region: PRK14993
527001003859	4Fe-4S binding domain; Region: Fer4; pfam00037
527001003860	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
527001003861	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
527001003862	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
527001003863	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001003864	dimer interface [polypeptide binding]; other site
527001003865	phosphorylation site [posttranslational modification]
527001003866	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001003867	ATP binding site [chemical binding]; other site
527001003868	Mg2+ binding site [ion binding]; other site
527001003869	G-X-G motif; other site
527001003870	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
527001003871	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001003872	active site
527001003873	phosphorylation site [posttranslational modification]
527001003874	intermolecular recognition site; other site
527001003875	dimerization interface [polypeptide binding]; other site
527001003876	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001003877	DNA binding residues [nucleotide binding]
527001003878	dimerization interface [polypeptide binding]; other site
527001003879	hypothetical protein; Provisional; Region: PRK10292
527001003880	Uncharacterized conserved protein [Function unknown]; Region: COG1683
527001003881	Uncharacterized conserved protein [Function unknown]; Region: COG3272
527001003882	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
527001003883	transcriptional regulator MirA; Provisional; Region: PRK15043
527001003884	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
527001003885	DNA binding residues [nucleotide binding]
527001003886	two component system sensor kinase SsrB; Provisional; Region: PRK15369
527001003887	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001003888	active site
527001003889	phosphorylation site [posttranslational modification]
527001003890	intermolecular recognition site; other site
527001003891	dimerization interface [polypeptide binding]; other site
527001003892	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001003893	DNA binding residues [nucleotide binding]
527001003894	dimerization interface [polypeptide binding]; other site
527001003895	two component system sensor kinase SsrA; Provisional; Region: PRK15347
527001003896	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001003897	dimerization interface [polypeptide binding]; other site
527001003898	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001003899	dimer interface [polypeptide binding]; other site
527001003900	phosphorylation site [posttranslational modification]
527001003901	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001003902	ATP binding site [chemical binding]; other site
527001003903	Mg2+ binding site [ion binding]; other site
527001003904	G-X-G motif; other site
527001003905	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001003906	active site
527001003907	phosphorylation site [posttranslational modification]
527001003908	intermolecular recognition site; other site
527001003909	dimerization interface [polypeptide binding]; other site
527001003910	pathogenicity island chaperone protein SpiC; Provisional; Region: PRK15368
527001003911	outer membrane secretin SsaC; Provisional; Region: PRK15346
527001003912	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
527001003913	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
527001003914	type III secretion system protein SsaD; Provisional; Region: PRK15367
527001003915	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
527001003916	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
527001003917	type III secretion system chaperone SseA; Provisional; Region: PRK15365
527001003918	pathogenicity island 2 effector protein SseB; Provisional; Region: PRK15364
527001003919	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
527001003920	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
527001003921	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
527001003922	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
527001003923	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
527001003924	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
527001003925	TPR motif; other site
527001003926	binding surface
527001003927	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
527001003928	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
527001003929	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
527001003930	type III secretion system protein SsaH; Provisional; Region: PRK15356
527001003931	type III secretion system protein SsaI; Provisional; Region: PRK15355
527001003932	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
527001003933	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
527001003934	type III secretion system protein SsaK; Provisional; Region: PRK15354
527001003935	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
527001003936	type III secretion system protein SsaL; Provisional; Region: PRK15345
527001003937	HrpJ-like domain; Region: HrpJ; pfam07201
527001003938	TyeA; Region: TyeA; cl07611
527001003939	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
527001003940	FHIPEP family; Region: FHIPEP; pfam00771
527001003941	type III secretion system ATPase SsaN; Validated; Region: PRK07594
527001003942	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
527001003943	Walker A motif; other site
527001003944	ATP binding site [chemical binding]; other site
527001003945	Walker B motif; other site
527001003946	type III secretion system protein SsaO; Provisional; Region: PRK15352
527001003947	type III secretion system protein SsaP; Provisional; Region: PRK15351
527001003948	type III secretion system protein SsaQ; Validated; Region: PRK08035
527001003949	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
527001003950	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
527001003951	type III secretion system protein SsaS; Provisional; Region: PRK15350
527001003952	type III secretion system protein SsaT; Provisional; Region: PRK15349
527001003953	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
527001003954	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
527001003955	multidrug efflux protein; Reviewed; Region: PRK01766
527001003956	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
527001003957	cation binding site [ion binding]; other site
527001003958	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
527001003959	Lumazine binding domain; Region: Lum_binding; pfam00677
527001003960	Lumazine binding domain; Region: Lum_binding; pfam00677
527001003961	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
527001003962	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001003963	S-adenosylmethionine binding site [chemical binding]; other site
527001003964	putative transporter; Provisional; Region: PRK11043
527001003965	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001003966	putative substrate translocation pore; other site
527001003967	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
527001003968	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001003969	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
527001003970	dimerization interface [polypeptide binding]; other site
527001003971	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
527001003972	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001003973	DNA binding site [nucleotide binding]
527001003974	domain linker motif; other site
527001003975	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
527001003976	dimerization interface [polypeptide binding]; other site
527001003977	ligand binding site [chemical binding]; other site
527001003978	superoxide dismutase; Provisional; Region: PRK10543
527001003979	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
527001003980	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
527001003981	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
527001003982	NlpC/P60 family; Region: NLPC_P60; pfam00877
527001003983	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
527001003984	putative GSH binding site [chemical binding]; other site
527001003985	catalytic residues [active]
527001003986	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
527001003987	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
527001003988	dimer interface [polypeptide binding]; other site
527001003989	catalytic site [active]
527001003990	putative active site [active]
527001003991	putative substrate binding site [chemical binding]; other site
527001003992	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
527001003993	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
527001003994	dimer interface [polypeptide binding]; other site
527001003995	active site
527001003996	metal binding site [ion binding]; metal-binding site
527001003997	glutathione binding site [chemical binding]; other site
527001003998	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
527001003999	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
527001004000	FMN binding site [chemical binding]; other site
527001004001	active site
527001004002	substrate binding site [chemical binding]; other site
527001004003	catalytic residue [active]
527001004004	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
527001004005	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001004006	Predicted Fe-S protein [General function prediction only]; Region: COG3313
527001004007	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
527001004008	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
527001004009	active site
527001004010	catalytic tetrad [active]
527001004011	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
527001004012	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
527001004013	E-class dimer interface [polypeptide binding]; other site
527001004014	P-class dimer interface [polypeptide binding]; other site
527001004015	active site
527001004016	Cu2+ binding site [ion binding]; other site
527001004017	Zn2+ binding site [ion binding]; other site
527001004018	Fusaric acid resistance protein family; Region: FUSC; pfam04632
527001004019	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
527001004020	RNA polymerase Rpb4; Region: RNA_pol_Rpb4; cl00638
527001004021	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
527001004022	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
527001004023	HlyD family secretion protein; Region: HlyD_3; pfam13437
527001004024	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
527001004025	transcriptional regulator SlyA; Provisional; Region: PRK03573
527001004026	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
527001004027	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
527001004028	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
527001004029	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
527001004030	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
527001004031	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
527001004032	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
527001004033	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
527001004034	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
527001004035	active site
527001004036	HIGH motif; other site
527001004037	dimer interface [polypeptide binding]; other site
527001004038	KMSKS motif; other site
527001004039	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
527001004040	RNA binding surface [nucleotide binding]; other site
527001004041	pyridoxamine kinase; Validated; Region: PRK05756
527001004042	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
527001004043	dimer interface [polypeptide binding]; other site
527001004044	pyridoxal binding site [chemical binding]; other site
527001004045	ATP binding site [chemical binding]; other site
527001004046	glutathionine S-transferase; Provisional; Region: PRK10542
527001004047	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
527001004048	C-terminal domain interface [polypeptide binding]; other site
527001004049	GSH binding site (G-site) [chemical binding]; other site
527001004050	dimer interface [polypeptide binding]; other site
527001004051	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
527001004052	dimer interface [polypeptide binding]; other site
527001004053	N-terminal domain interface [polypeptide binding]; other site
527001004054	substrate binding pocket (H-site) [chemical binding]; other site
527001004055	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
527001004056	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001004057	putative substrate translocation pore; other site
527001004058	POT family; Region: PTR2; pfam00854
527001004059	endonuclease III; Provisional; Region: PRK10702
527001004060	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
527001004061	minor groove reading motif; other site
527001004062	helix-hairpin-helix signature motif; other site
527001004063	substrate binding pocket [chemical binding]; other site
527001004064	active site
527001004065	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
527001004066	electron transport complex RsxE subunit; Provisional; Region: PRK12405
527001004067	electron transport complex protein RnfG; Validated; Region: PRK01908
527001004068	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
527001004069	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
527001004070	SLBB domain; Region: SLBB; pfam10531
527001004071	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
527001004072	electron transport complex protein RnfB; Provisional; Region: PRK05113
527001004073	Putative Fe-S cluster; Region: FeS; cl17515
527001004074	4Fe-4S binding domain; Region: Fer4; pfam00037
527001004075	electron transport complex protein RsxA; Provisional; Region: PRK05151
527001004076	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
527001004077	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
527001004078	putative oxidoreductase; Provisional; Region: PRK11579
527001004079	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
527001004080	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
527001004081	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
527001004082	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
527001004083	active site
527001004084	purine riboside binding site [chemical binding]; other site
527001004085	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
527001004086	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
527001004087	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
527001004088	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
527001004089	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
527001004090	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
527001004091	fumarate hydratase; Provisional; Region: PRK15389
527001004092	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
527001004093	Fumarase C-terminus; Region: Fumerase_C; pfam05683
527001004094	fumarate hydratase; Reviewed; Region: fumC; PRK00485
527001004095	Class II fumarases; Region: Fumarase_classII; cd01362
527001004096	active site
527001004097	tetramer interface [polypeptide binding]; other site
527001004098	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
527001004099	sensor protein RstB; Provisional; Region: PRK10604
527001004100	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001004101	dimerization interface [polypeptide binding]; other site
527001004102	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001004103	dimer interface [polypeptide binding]; other site
527001004104	phosphorylation site [posttranslational modification]
527001004105	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001004106	ATP binding site [chemical binding]; other site
527001004107	Mg2+ binding site [ion binding]; other site
527001004108	G-X-G motif; other site
527001004109	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
527001004110	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
527001004111	active site
527001004112	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
527001004113	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
527001004114	trimer interface [polypeptide binding]; other site
527001004115	eyelet of channel; other site
527001004116	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
527001004117	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001004118	active site
527001004119	phosphorylation site [posttranslational modification]
527001004120	intermolecular recognition site; other site
527001004121	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001004122	DNA binding site [nucleotide binding]
527001004123	GlpM protein; Region: GlpM; pfam06942
527001004124	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
527001004125	Spore germination protein; Region: Spore_permease; cl17796
527001004126	multiple promoter invertase; Provisional; Region: mpi; PRK13413
527001004127	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
527001004128	catalytic residues [active]
527001004129	catalytic nucleophile [active]
527001004130	Presynaptic Site I dimer interface [polypeptide binding]; other site
527001004131	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
527001004132	Synaptic Flat tetramer interface [polypeptide binding]; other site
527001004133	Synaptic Site I dimer interface [polypeptide binding]; other site
527001004134	DNA binding site [nucleotide binding]
527001004135	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
527001004136	DNA-binding interface [nucleotide binding]; DNA binding site
527001004137	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
527001004138	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
527001004139	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
527001004140	Phage Tail Collar Domain; Region: Collar; pfam07484
527001004141	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684
527001004142	Baseplate J-like protein; Region: Baseplate_J; cl01294
527001004143	Phage baseplate assembly protein W [General function prediction only]; Region: COG3628
527001004144	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
527001004145	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
527001004146	Phage protein D [General function prediction only]; Region: COG3500
527001004147	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
527001004148	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
527001004149	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
527001004150	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
527001004151	phage contractile tail tube protein, P2 family; Region: tail_tube; TIGR01611
527001004152	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
527001004153	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
527001004154	Gp37 protein; Region: Gp37; pfam09646
527001004155	Protein of unknown function (DUF1320); Region: DUF1320; pfam07030
527001004156	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
527001004157	Phage Mu protein F like protein; Region: Phage_Mu_F; pfam04233
527001004158	Protein of unknown function (DUF935); Region: DUF935; pfam06074
527001004159	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
527001004160	Terminase-like family; Region: Terminase_6; pfam03237
527001004161	Protein of unknown function (DUF3486); Region: DUF3486; pfam11985
527001004162	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK06476
527001004163	acetolactate synthase 3 catalytic subunit; Reviewed; Region: PRK06048
527001004164	phage lambda Rz-like lysis protein; Region: PHA00276
527001004165	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
527001004166	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
527001004167	N-acetyl-D-glucosamine binding site [chemical binding]; other site
527001004168	catalytic residue [active]
527001004169	Protein of unknown function (DUF4063); Region: DUF4063; pfam13272
527001004170	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
527001004171	Integrase core domain; Region: rve; pfam00665
527001004172	Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]; Region: ExeA; COG3267
527001004173	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001004174	Walker A/P-loop; other site
527001004175	ATP binding site [chemical binding]; other site
527001004176	Bacteriophage Mu Gam like protein; Region: Phage_Mu_Gam; cl01825
527001004177	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u2; cd11539
527001004178	metal binding site [ion binding]; metal-binding site
527001004179	Protein of unknown function (DUF1018); Region: DUF1018; pfam06252
527001004180	Mor transcription activator family; Region: Mor; pfam08765
527001004181	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
527001004182	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
527001004183	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
527001004184	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
527001004185	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
527001004186	ligand binding site [chemical binding]; other site
527001004187	homodimer interface [polypeptide binding]; other site
527001004188	NAD(P) binding site [chemical binding]; other site
527001004189	trimer interface B [polypeptide binding]; other site
527001004190	trimer interface A [polypeptide binding]; other site
527001004191	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
527001004192	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
527001004193	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
527001004194	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
527001004195	Domain of unknown function DUF20; Region: UPF0118; pfam01594
527001004196	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
527001004197	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
527001004198	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
527001004199	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001004200	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
527001004201	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001004202	putative substrate translocation pore; other site
527001004203	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
527001004204	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001004205	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
527001004206	dimerization interface [polypeptide binding]; other site
527001004207	substrate binding pocket [chemical binding]; other site
527001004208	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
527001004209	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
527001004210	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
527001004211	nucleotide binding site [chemical binding]; other site
527001004212	putative dithiobiotin synthetase; Provisional; Region: PRK12374
527001004213	AAA domain; Region: AAA_26; pfam13500
527001004214	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
527001004215	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
527001004216	Cl- selectivity filter; other site
527001004217	Cl- binding residues [ion binding]; other site
527001004218	pore gating glutamate residue; other site
527001004219	dimer interface [polypeptide binding]; other site
527001004220	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
527001004221	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
527001004222	Walker A/P-loop; other site
527001004223	ATP binding site [chemical binding]; other site
527001004224	Q-loop/lid; other site
527001004225	ABC transporter signature motif; other site
527001004226	Walker B; other site
527001004227	D-loop; other site
527001004228	H-loop/switch region; other site
527001004229	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
527001004230	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001004231	dimer interface [polypeptide binding]; other site
527001004232	conserved gate region; other site
527001004233	ABC-ATPase subunit interface; other site
527001004234	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
527001004235	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001004236	dimer interface [polypeptide binding]; other site
527001004237	conserved gate region; other site
527001004238	putative PBP binding loops; other site
527001004239	ABC-ATPase subunit interface; other site
527001004240	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
527001004241	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
527001004242	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
527001004243	4Fe-4S binding domain; Region: Fer4; pfam00037
527001004244	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
527001004245	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
527001004246	putative [Fe4-S4] binding site [ion binding]; other site
527001004247	putative molybdopterin cofactor binding site [chemical binding]; other site
527001004248	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
527001004249	putative molybdopterin cofactor binding site; other site
527001004250	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
527001004251	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
527001004252	putative [Fe4-S4] binding site [ion binding]; other site
527001004253	putative molybdopterin cofactor binding site [chemical binding]; other site
527001004254	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
527001004255	putative molybdopterin cofactor binding site; other site
527001004256	potential frameshift: common BLAST hit: gi|16764845|ref|NP_460460.1| putative outer membrane protein
527001004257	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
527001004258	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
527001004259	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001004260	Coenzyme A binding pocket [chemical binding]; other site
527001004261	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
527001004262	hypothetical protein; Provisional; Region: PRK13659
527001004263	hypothetical protein; Provisional; Region: PRK02237
527001004264	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
527001004265	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
527001004266	putative active site pocket [active]
527001004267	putative metal binding site [ion binding]; other site
527001004268	putative oxidoreductase; Provisional; Region: PRK10083
527001004269	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
527001004270	putative NAD(P) binding site [chemical binding]; other site
527001004271	catalytic Zn binding site [ion binding]; other site
527001004272	structural Zn binding site [ion binding]; other site
527001004273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001004274	metabolite-proton symporter; Region: 2A0106; TIGR00883
527001004275	putative substrate translocation pore; other site
527001004276	potential frameshift: common BLAST hit: gi|197247746|ref|YP_002146534.1| D-mannonate oxidoreductase
527001004277	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
527001004278	Transcriptional regulators [Transcription]; Region: GntR; COG1802
527001004279	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001004280	DNA-binding site [nucleotide binding]; DNA binding site
527001004281	FCD domain; Region: FCD; pfam07729
527001004282	malonic semialdehyde reductase; Provisional; Region: PRK10538
527001004283	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
527001004284	putative NAD(P) binding site [chemical binding]; other site
527001004285	homodimer interface [polypeptide binding]; other site
527001004286	homotetramer interface [polypeptide binding]; other site
527001004287	active site
527001004288	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
527001004289	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
527001004290	active site
527001004291	Zn binding site [ion binding]; other site
527001004292	General stress protein [General function prediction only]; Region: GsiB; COG3729
527001004293	hypothetical protein; Validated; Region: PRK03657
527001004294	hypothetical protein; Provisional; Region: PRK10053
527001004295	putative transporter; Provisional; Region: PRK10054
527001004296	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001004297	putative substrate translocation pore; other site
527001004298	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
527001004299	EamA-like transporter family; Region: EamA; pfam00892
527001004300	MarB protein; Region: MarB; pfam13999
527001004301	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
527001004302	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001004303	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001004304	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
527001004305	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
527001004306	inner membrane protein; Provisional; Region: PRK10995
527001004307	putative arabinose transporter; Provisional; Region: PRK03545
527001004308	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001004309	putative substrate translocation pore; other site
527001004310	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001004311	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001004312	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
527001004313	putative dimerization interface [polypeptide binding]; other site
527001004314	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
527001004315	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
527001004316	NAD(P) binding site [chemical binding]; other site
527001004317	catalytic residues [active]
527001004318	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
527001004319	glutaminase; Provisional; Region: PRK00971
527001004320	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
527001004321	Predicted membrane protein [Function unknown]; Region: COG3781
527001004322	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
527001004323	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
527001004324	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
527001004325	trimer interface [polypeptide binding]; other site
527001004326	eyelet of channel; other site
527001004327	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
527001004328	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
527001004329	Rubredoxin [Energy production and conversion]; Region: COG1773
527001004330	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
527001004331	iron binding site [ion binding]; other site
527001004332	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
527001004333	HupF/HypC family; Region: HupF_HypC; cl00394
527001004334	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
527001004335	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
527001004336	putative substrate-binding site; other site
527001004337	nickel binding site [ion binding]; other site
527001004338	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
527001004339	potential frameshift: common BLAST hit: gi|197248299|ref|YP_002146505.1| [Ni/Fe] hydrogenase, large subunit
527001004340	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
527001004341	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
527001004342	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
527001004343	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
527001004344	active site
527001004345	Transcriptional regulators [Transcription]; Region: FadR; COG2186
527001004346	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001004347	DNA-binding site [nucleotide binding]; DNA binding site
527001004348	FCD domain; Region: FCD; pfam07729
527001004349	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
527001004350	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
527001004351	putative NAD(P) binding site [chemical binding]; other site
527001004352	catalytic Zn binding site [ion binding]; other site
527001004353	structural Zn binding site [ion binding]; other site
527001004354	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001004355	D-galactonate transporter; Region: 2A0114; TIGR00893
527001004356	putative substrate translocation pore; other site
527001004357	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
527001004358	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001004359	Major Facilitator Superfamily; Region: MFS_1; pfam07690
527001004360	putative substrate translocation pore; other site
527001004361	Transcriptional regulators [Transcription]; Region: MarR; COG1846
527001004362	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
527001004363	putative DNA binding site [nucleotide binding]; other site
527001004364	putative Zn2+ binding site [ion binding]; other site
527001004365	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
527001004366	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
527001004367	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cl10015
527001004368	homotrimer interaction site [polypeptide binding]; other site
527001004369	putative active site [active]
527001004370	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
527001004371	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
527001004372	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
527001004373	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001004374	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001004375	homodimer interface [polypeptide binding]; other site
527001004376	catalytic residue [active]
527001004377	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
527001004378	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
527001004379	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
527001004380	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
527001004381	active site
527001004382	catalytic site [active]
527001004383	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
527001004384	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
527001004385	active site
527001004386	catalytic site [active]
527001004387	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
527001004388	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
527001004389	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
527001004390	catalytic site [active]
527001004391	active site
527001004392	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
527001004393	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
527001004394	acid-resistance protein; Provisional; Region: hdeB; PRK11566
527001004395	Haemolysin E (HlyE); Region: HlyE; cl11627
527001004396	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
527001004397	biofilm-dependent modulation protein; Provisional; Region: PRK11436
527001004398	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
527001004399	malate dehydrogenase; Provisional; Region: PRK13529
527001004400	Malic enzyme, N-terminal domain; Region: malic; pfam00390
527001004401	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
527001004402	NAD(P) binding site [chemical binding]; other site
527001004403	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
527001004404	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
527001004405	NAD binding site [chemical binding]; other site
527001004406	substrate binding site [chemical binding]; other site
527001004407	catalytic Zn binding site [ion binding]; other site
527001004408	tetramer interface [polypeptide binding]; other site
527001004409	structural Zn binding site [ion binding]; other site
527001004410	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
527001004411	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
527001004412	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
527001004413	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
527001004414	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001004415	putative substrate translocation pore; other site
527001004416	TetR family transcriptional regulator; Provisional; Region: PRK14996
527001004417	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001004418	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
527001004419	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
527001004420	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
527001004421	[4Fe-4S] binding site [ion binding]; other site
527001004422	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
527001004423	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
527001004424	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
527001004425	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
527001004426	molybdopterin cofactor binding site; other site
527001004427	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
527001004428	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
527001004429	hypothetical protein; Provisional; Region: PRK10281
527001004430	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
527001004431	L-asparagine permease; Provisional; Region: PRK15049
527001004432	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
527001004433	Uncharacterized conserved protein [Function unknown]; Region: COG3391
527001004434	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
527001004435	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
527001004436	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
527001004437	N-terminal plug; other site
527001004438	ligand-binding site [chemical binding]; other site
527001004439	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
527001004440	DNA-binding site [nucleotide binding]; DNA binding site
527001004441	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
527001004442	FCD domain; Region: FCD; pfam07729
527001004443	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
527001004444	Prostaglandin dehydrogenases; Region: PGDH; cd05288
527001004445	NAD(P) binding site [chemical binding]; other site
527001004446	substrate binding site [chemical binding]; other site
527001004447	dimer interface [polypeptide binding]; other site
527001004448	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
527001004449	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
527001004450	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
527001004451	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
527001004452	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
527001004453	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
527001004454	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
527001004455	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
527001004456	tetrameric interface [polypeptide binding]; other site
527001004457	NAD binding site [chemical binding]; other site
527001004458	catalytic residues [active]
527001004459	substrate binding site [chemical binding]; other site
527001004460	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
527001004461	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001004462	DNA-binding site [nucleotide binding]; DNA binding site
527001004463	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001004464	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001004465	homodimer interface [polypeptide binding]; other site
527001004466	catalytic residue [active]
527001004467	D-alanyl-D-alanine dipeptidase [Cell envelope biogenesis, outer membrane]; Region: DdpX; COG2173
527001004468	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
527001004469	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
527001004470	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
527001004471	Peptidase family U32; Region: Peptidase_U32; pfam01136
527001004472	Collagenase; Region: DUF3656; pfam12392
527001004473	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
527001004474	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001004475	non-specific DNA binding site [nucleotide binding]; other site
527001004476	salt bridge; other site
527001004477	sequence-specific DNA binding site [nucleotide binding]; other site
527001004478	Cupin domain; Region: Cupin_2; pfam07883
527001004479	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
527001004480	benzoate transporter; Region: benE; TIGR00843
527001004481	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
527001004482	tellurite resistance protein TehB; Provisional; Region: PRK11207
527001004483	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001004484	S-adenosylmethionine binding site [chemical binding]; other site
527001004485	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
527001004486	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
527001004487	gating phenylalanine in ion channel; other site
527001004488	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
527001004489	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
527001004490	putative trimer interface [polypeptide binding]; other site
527001004491	putative CoA binding site [chemical binding]; other site
527001004492	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
527001004493	putative trimer interface [polypeptide binding]; other site
527001004494	putative CoA binding site [chemical binding]; other site
527001004495	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
527001004496	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001004497	Coenzyme A binding pocket [chemical binding]; other site
527001004498	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
527001004499	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
527001004500	oligomer interface [polypeptide binding]; other site
527001004501	active site
527001004502	metal binding site [ion binding]; metal-binding site
527001004503	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
527001004504	active site
527001004505	P-loop; other site
527001004506	phosphorylation site [posttranslational modification]
527001004507	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
527001004508	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
527001004509	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
527001004510	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
527001004511	active site
527001004512	phosphorylation site [posttranslational modification]
527001004513	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
527001004514	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
527001004515	substrate binding site [chemical binding]; other site
527001004516	hexamer interface [polypeptide binding]; other site
527001004517	metal binding site [ion binding]; metal-binding site
527001004518	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
527001004519	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
527001004520	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001004521	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001004522	Coenzyme A binding pocket [chemical binding]; other site
527001004523	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
527001004524	teramer interface [polypeptide binding]; other site
527001004525	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
527001004526	active site
527001004527	FMN binding site [chemical binding]; other site
527001004528	catalytic residues [active]
527001004529	Uncharacterized conserved protein [Function unknown]; Region: COG2353
527001004530	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
527001004531	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
527001004532	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
527001004533	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
527001004534	substrate binding pocket [chemical binding]; other site
527001004535	catalytic triad [active]
527001004536	Domain of unknown function (DUF1338); Region: DUF1338; pfam07063
527001004537	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
527001004538	Predicted membrane protein [Function unknown]; Region: COG3326
527001004539	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001004540	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
527001004541	substrate binding pocket [chemical binding]; other site
527001004542	membrane-bound complex binding site; other site
527001004543	hinge residues; other site
527001004544	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
527001004545	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001004546	dimer interface [polypeptide binding]; other site
527001004547	conserved gate region; other site
527001004548	putative PBP binding loops; other site
527001004549	ABC-ATPase subunit interface; other site
527001004550	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
527001004551	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001004552	Walker A/P-loop; other site
527001004553	ATP binding site [chemical binding]; other site
527001004554	Q-loop/lid; other site
527001004555	ABC transporter signature motif; other site
527001004556	Walker B; other site
527001004557	D-loop; other site
527001004558	H-loop/switch region; other site
527001004559	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
527001004560	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001004561	dimer interface [polypeptide binding]; other site
527001004562	conserved gate region; other site
527001004563	putative PBP binding loops; other site
527001004564	ABC-ATPase subunit interface; other site
527001004565	Predicted membrane protein [Function unknown]; Region: COG5305
527001004566	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001004567	S-adenosylmethionine binding site [chemical binding]; other site
527001004568	Uncharacterized conserved protein [Function unknown]; Region: COG1434
527001004569	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
527001004570	putative active site [active]
527001004571	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
527001004572	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001004573	ATP binding site [chemical binding]; other site
527001004574	putative Mg++ binding site [ion binding]; other site
527001004575	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001004576	nucleotide binding region [chemical binding]; other site
527001004577	ATP-binding site [chemical binding]; other site
527001004578	Helicase associated domain (HA2); Region: HA2; pfam04408
527001004579	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
527001004580	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
527001004581	azoreductase; Reviewed; Region: PRK00170
527001004582	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
527001004583	Uncharacterized conserved protein [Function unknown]; Region: COG3791
527001004584	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
527001004585	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
527001004586	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
527001004587	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
527001004588	putative ligand binding site [chemical binding]; other site
527001004589	putative NAD binding site [chemical binding]; other site
527001004590	catalytic site [active]
527001004591	heat-inducible protein; Provisional; Region: PRK10449
527001004592	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
527001004593	Domain of unknown function (DUF333); Region: DUF333; pfam03891
527001004594	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
527001004595	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
527001004596	dimer interface [polypeptide binding]; other site
527001004597	PYR/PP interface [polypeptide binding]; other site
527001004598	TPP binding site [chemical binding]; other site
527001004599	substrate binding site [chemical binding]; other site
527001004600	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
527001004601	Domain of unknown function; Region: EKR; smart00890
527001004602	4Fe-4S binding domain; Region: Fer4_6; pfam12837
527001004603	4Fe-4S binding domain; Region: Fer4; pfam00037
527001004604	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
527001004605	TPP-binding site [chemical binding]; other site
527001004606	dimer interface [polypeptide binding]; other site
527001004607	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001004608	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
527001004609	Ligand Binding Site [chemical binding]; other site
527001004610	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
527001004611	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
527001004612	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
527001004613	Ligand Binding Site [chemical binding]; other site
527001004614	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
527001004615	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
527001004616	ATP binding site [chemical binding]; other site
527001004617	Mg++ binding site [ion binding]; other site
527001004618	motif III; other site
527001004619	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001004620	nucleotide binding region [chemical binding]; other site
527001004621	ATP-binding site [chemical binding]; other site
527001004622	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
527001004623	putative RNA binding site [nucleotide binding]; other site
527001004624	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
527001004625	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
527001004626	Cl binding site [ion binding]; other site
527001004627	oligomer interface [polypeptide binding]; other site
527001004628	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
527001004629	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
527001004630	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
527001004631	dimer interface [polypeptide binding]; other site
527001004632	putative CheW interface [polypeptide binding]; other site
527001004633	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
527001004634	Smr domain; Region: Smr; pfam01713
527001004635	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
527001004636	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
527001004637	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
527001004638	DNA binding site [nucleotide binding]
527001004639	active site
527001004640	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
527001004641	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
527001004642	ligand binding site [chemical binding]; other site
527001004643	flexible hinge region; other site
527001004644	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
527001004645	putative switch regulator; other site
527001004646	non-specific DNA interactions [nucleotide binding]; other site
527001004647	DNA binding site [nucleotide binding]
527001004648	sequence specific DNA binding site [nucleotide binding]; other site
527001004649	putative cAMP binding site [chemical binding]; other site
527001004650	universal stress protein UspE; Provisional; Region: PRK11175
527001004651	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
527001004652	Ligand Binding Site [chemical binding]; other site
527001004653	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
527001004654	Ligand Binding Site [chemical binding]; other site
527001004655	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
527001004656	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
527001004657	Mechanosensitive ion channel; Region: MS_channel; pfam00924
527001004658	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
527001004659	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001004660	non-specific DNA binding site [nucleotide binding]; other site
527001004661	salt bridge; other site
527001004662	sequence-specific DNA binding site [nucleotide binding]; other site
527001004663	Cupin domain; Region: Cupin_2; pfam07883
527001004664	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
527001004665	B3/4 domain; Region: B3_4; pfam03483
527001004666	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: Tpx; COG2077
527001004667	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
527001004668	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
527001004669	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001004670	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
527001004671	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
527001004672	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
527001004673	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001004674	oxidoreductase; Provisional; Region: PRK12742
527001004675	classical (c) SDRs; Region: SDR_c; cd05233
527001004676	NAD(P) binding site [chemical binding]; other site
527001004677	active site
527001004678	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
527001004679	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
527001004680	active site
527001004681	catalytic tetrad [active]
527001004682	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001004683	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001004684	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
527001004685	putative effector binding pocket; other site
527001004686	putative dimerization interface [polypeptide binding]; other site
527001004687	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
527001004688	NmrA-like family; Region: NmrA; pfam05368
527001004689	NAD(P) binding site [chemical binding]; other site
527001004690	active site lysine
527001004691	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
527001004692	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
527001004693	peptide binding site [polypeptide binding]; other site
527001004694	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
527001004695	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
527001004696	putative active site [active]
527001004697	Zn binding site [ion binding]; other site
527001004698	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
527001004699	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
527001004700	active site
527001004701	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
527001004702	dimer interface [polypeptide binding]; other site
527001004703	catalytic triad [active]
527001004704	peroxidatic and resolving cysteines [active]
527001004705	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001004706	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
527001004707	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
527001004708	putative aromatic amino acid binding site; other site
527001004709	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001004710	Walker A motif; other site
527001004711	ATP binding site [chemical binding]; other site
527001004712	Walker B motif; other site
527001004713	arginine finger; other site
527001004714	hypothetical protein; Provisional; Region: PRK05415
527001004715	TIGR01620 family protein; Region: hyp_HI0043
527001004716	Predicted ATPase [General function prediction only]; Region: COG3106
527001004717	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
527001004718	active site residue [active]
527001004719	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
527001004720	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
527001004721	phage shock protein C; Region: phageshock_pspC; TIGR02978
527001004722	phage shock protein B; Provisional; Region: pspB; PRK09458
527001004723	phage shock protein PspA; Provisional; Region: PRK10698
527001004724	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
527001004725	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001004726	Walker A motif; other site
527001004727	ATP binding site [chemical binding]; other site
527001004728	Walker B motif; other site
527001004729	arginine finger; other site
527001004730	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
527001004731	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
527001004732	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
527001004733	peptide binding site [polypeptide binding]; other site
527001004734	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
527001004735	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001004736	dimer interface [polypeptide binding]; other site
527001004737	conserved gate region; other site
527001004738	putative PBP binding loops; other site
527001004739	ABC-ATPase subunit interface; other site
527001004740	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
527001004741	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
527001004742	subtilase cytotoxin subunit B-like protein; Provisional; Region: PRK15267
527001004743	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
527001004744	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
527001004745	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
527001004746	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
527001004747	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001004748	dimer interface [polypeptide binding]; other site
527001004749	conserved gate region; other site
527001004750	putative PBP binding loops; other site
527001004751	ABC-ATPase subunit interface; other site
527001004752	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
527001004753	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001004754	Walker A/P-loop; other site
527001004755	ATP binding site [chemical binding]; other site
527001004756	Q-loop/lid; other site
527001004757	ABC transporter signature motif; other site
527001004758	Walker B; other site
527001004759	D-loop; other site
527001004760	H-loop/switch region; other site
527001004761	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
527001004762	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
527001004763	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001004764	Walker A/P-loop; other site
527001004765	ATP binding site [chemical binding]; other site
527001004766	Q-loop/lid; other site
527001004767	ABC transporter signature motif; other site
527001004768	Walker B; other site
527001004769	D-loop; other site
527001004770	H-loop/switch region; other site
527001004771	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
527001004772	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
527001004773	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
527001004774	NAD binding site [chemical binding]; other site
527001004775	homotetramer interface [polypeptide binding]; other site
527001004776	homodimer interface [polypeptide binding]; other site
527001004777	substrate binding site [chemical binding]; other site
527001004778	active site
527001004779	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
527001004780	exoribonuclease II; Provisional; Region: PRK05054
527001004781	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
527001004782	RNB domain; Region: RNB; pfam00773
527001004783	S1 RNA binding domain; Region: S1; pfam00575
527001004784	RNase II stability modulator; Provisional; Region: PRK10060
527001004785	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
527001004786	putative active site [active]
527001004787	heme pocket [chemical binding]; other site
527001004788	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001004789	metal binding site [ion binding]; metal-binding site
527001004790	active site
527001004791	I-site; other site
527001004792	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001004793	hypothetical protein; Provisional; Region: PRK13658
527001004794	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
527001004795	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
527001004796	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001004797	lipoprotein; Provisional; Region: PRK10540
527001004798	translation initiation factor Sui1; Validated; Region: PRK06824
527001004799	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
527001004800	putative rRNA binding site [nucleotide binding]; other site
527001004801	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
527001004802	active site
527001004803	dimer interface [polypeptide binding]; other site
527001004804	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
527001004805	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
527001004806	binding surface
527001004807	TPR motif; other site
527001004808	Predicted membrane protein [Function unknown]; Region: COG3771
527001004809	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
527001004810	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
527001004811	active site
527001004812	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
527001004813	dimerization interface [polypeptide binding]; other site
527001004814	active site
527001004815	aconitate hydratase; Validated; Region: PRK09277
527001004816	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
527001004817	substrate binding site [chemical binding]; other site
527001004818	ligand binding site [chemical binding]; other site
527001004819	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
527001004820	substrate binding site [chemical binding]; other site
527001004821	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
527001004822	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001004823	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
527001004824	substrate binding site [chemical binding]; other site
527001004825	putative dimerization interface [polypeptide binding]; other site
527001004826	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
527001004827	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
527001004828	active site
527001004829	interdomain interaction site; other site
527001004830	putative metal-binding site [ion binding]; other site
527001004831	nucleotide binding site [chemical binding]; other site
527001004832	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
527001004833	domain I; other site
527001004834	DNA binding groove [nucleotide binding]
527001004835	phosphate binding site [ion binding]; other site
527001004836	domain II; other site
527001004837	domain III; other site
527001004838	nucleotide binding site [chemical binding]; other site
527001004839	catalytic site [active]
527001004840	domain IV; other site
527001004841	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
527001004842	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
527001004843	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
527001004844	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
527001004845	hypothetical protein; Provisional; Region: PRK11037
527001004846	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
527001004847	putative inner membrane peptidase; Provisional; Region: PRK11778
527001004848	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
527001004849	tandem repeat interface [polypeptide binding]; other site
527001004850	oligomer interface [polypeptide binding]; other site
527001004851	active site residues [active]
527001004852	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
527001004853	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
527001004854	NADP binding site [chemical binding]; other site
527001004855	homodimer interface [polypeptide binding]; other site
527001004856	active site
527001004857	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
527001004858	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
527001004859	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
527001004860	homodimer interface [polypeptide binding]; other site
527001004861	Walker A motif; other site
527001004862	ATP binding site [chemical binding]; other site
527001004863	hydroxycobalamin binding site [chemical binding]; other site
527001004864	Walker B motif; other site
527001004865	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
527001004866	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
527001004867	RNA binding surface [nucleotide binding]; other site
527001004868	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
527001004869	probable active site [active]
527001004870	hypothetical protein; Provisional; Region: PRK11630
527001004871	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
527001004872	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
527001004873	active site
527001004874	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
527001004875	anthranilate synthase component I; Provisional; Region: PRK13564
527001004876	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
527001004877	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
527001004878	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
527001004879	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
527001004880	glutamine binding [chemical binding]; other site
527001004881	catalytic triad [active]
527001004882	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
527001004883	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
527001004884	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
527001004885	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
527001004886	active site
527001004887	ribulose/triose binding site [chemical binding]; other site
527001004888	phosphate binding site [ion binding]; other site
527001004889	substrate (anthranilate) binding pocket [chemical binding]; other site
527001004890	product (indole) binding pocket [chemical binding]; other site
527001004891	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
527001004892	active site
527001004893	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
527001004894	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
527001004895	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001004896	catalytic residue [active]
527001004897	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
527001004898	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
527001004899	substrate binding site [chemical binding]; other site
527001004900	active site
527001004901	catalytic residues [active]
527001004902	heterodimer interface [polypeptide binding]; other site
527001004903	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
527001004904	dimerization interface [polypeptide binding]; other site
527001004905	metal binding site [ion binding]; metal-binding site
527001004906	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
527001004907	dinuclear metal binding motif [ion binding]; other site
527001004908	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
527001004909	dimanganese center [ion binding]; other site
527001004910	outer membrane protein W; Provisional; Region: PRK10959
527001004911	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
527001004912	hypothetical protein; Provisional; Region: PRK02868
527001004913	intracellular septation protein A; Reviewed; Region: PRK00259
527001004914	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
527001004915	transport protein TonB; Provisional; Region: PRK10819
527001004916	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
527001004917	YciI-like protein; Reviewed; Region: PRK11370
527001004918	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
527001004919	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
527001004920	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
527001004921	putative active site [active]
527001004922	catalytic site [active]
527001004923	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
527001004924	putative active site [active]
527001004925	catalytic site [active]
527001004926	dsDNA-mimic protein; Reviewed; Region: PRK05094
527001004927	Ion transport protein; Region: Ion_trans; pfam00520
527001004928	Ion channel; Region: Ion_trans_2; pfam07885
527001004929	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
527001004930	Double zinc ribbon; Region: DZR; pfam12773
527001004931	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
527001004932	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001004933	Walker A/P-loop; other site
527001004934	ATP binding site [chemical binding]; other site
527001004935	Q-loop/lid; other site
527001004936	ABC transporter signature motif; other site
527001004937	Walker B; other site
527001004938	D-loop; other site
527001004939	H-loop/switch region; other site
527001004940	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
527001004941	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
527001004942	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001004943	Walker A/P-loop; other site
527001004944	ATP binding site [chemical binding]; other site
527001004945	Q-loop/lid; other site
527001004946	ABC transporter signature motif; other site
527001004947	Walker B; other site
527001004948	D-loop; other site
527001004949	H-loop/switch region; other site
527001004950	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
527001004951	potential frameshift: common BLAST hit: gi|197251525|ref|YP_002146283.1| oligopeptide ABC transporter, permease protein OppC
527001004952	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
527001004953	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001004954	dimer interface [polypeptide binding]; other site
527001004955	conserved gate region; other site
527001004956	putative PBP binding loops; other site
527001004957	ABC-ATPase subunit interface; other site
527001004958	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
527001004959	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
527001004960	peptide binding site [polypeptide binding]; other site
527001004961	hypothetical protein; Provisional; Region: PRK11111
527001004962	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
527001004963	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
527001004964	putative catalytic cysteine [active]
527001004965	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
527001004966	putative active site [active]
527001004967	metal binding site [ion binding]; metal-binding site
527001004968	thymidine kinase; Provisional; Region: PRK04296
527001004969	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
527001004970	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
527001004971	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
527001004972	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
527001004973	active site
527001004974	tetramer interface; other site
527001004975	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001004976	active site
527001004977	response regulator of RpoS; Provisional; Region: PRK10693
527001004978	phosphorylation site [posttranslational modification]
527001004979	intermolecular recognition site; other site
527001004980	dimerization interface [polypeptide binding]; other site
527001004981	hypothetical protein; Provisional; Region: PRK10279
527001004982	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
527001004983	active site
527001004984	nucleophile elbow; other site
527001004985	hypothetical protein; Provisional; Region: PRK01617
527001004986	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
527001004987	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
527001004988	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
527001004989	putative active site [active]
527001004990	putative substrate binding site [chemical binding]; other site
527001004991	putative cosubstrate binding site; other site
527001004992	catalytic site [active]
527001004993	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
527001004994	Sel1-like repeats; Region: SEL1; smart00671
527001004995	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
527001004996	Sel1-like repeats; Region: SEL1; smart00671
527001004997	Sel1-like repeats; Region: SEL1; smart00671
527001004998	Sel1-like repeats; Region: SEL1; smart00671
527001004999	Sel1-like repeats; Region: SEL1; smart00671
527001005000	Sel1-like repeats; Region: SEL1; smart00671
527001005001	Sel1-like repeats; Region: SEL1; smart00671
527001005002	Sel1-like repeats; Region: SEL1; smart00671
527001005003	Sel1-like repeats; Region: SEL1; smart00671
527001005004	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
527001005005	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
527001005006	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
527001005007	4Fe-4S binding domain; Region: Fer4; cl02805
527001005008	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
527001005009	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
527001005010	[4Fe-4S] binding site [ion binding]; other site
527001005011	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
527001005012	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
527001005013	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
527001005014	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
527001005015	molybdopterin cofactor binding site; other site
527001005016	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
527001005017	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
527001005018	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
527001005019	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001005020	dimerization interface [polypeptide binding]; other site
527001005021	Histidine kinase; Region: HisKA_3; pfam07730
527001005022	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001005023	ATP binding site [chemical binding]; other site
527001005024	Mg2+ binding site [ion binding]; other site
527001005025	G-X-G motif; other site
527001005026	transcriptional regulator NarL; Provisional; Region: PRK10651
527001005027	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001005028	active site
527001005029	phosphorylation site [posttranslational modification]
527001005030	intermolecular recognition site; other site
527001005031	dimerization interface [polypeptide binding]; other site
527001005032	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001005033	DNA binding residues [nucleotide binding]
527001005034	dimerization interface [polypeptide binding]; other site
527001005035	putative invasin; Provisional; Region: PRK10177
527001005036	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
527001005037	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
527001005038	cation transport regulator; Reviewed; Region: chaB; PRK09582
527001005039	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
527001005040	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
527001005041	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001005042	isocitrate dehydrogenase; Validated; Region: PRK07362
527001005043	isocitrate dehydrogenase; Reviewed; Region: PRK07006
527001005044	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
527001005045	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
527001005046	probable active site [active]
527001005047	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
527001005048	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
527001005049	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
527001005050	nudix motif; other site
527001005051	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
527001005052	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
527001005053	putative lysogenization regulator; Reviewed; Region: PRK00218
527001005054	adenylosuccinate lyase; Provisional; Region: PRK09285
527001005055	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
527001005056	tetramer interface [polypeptide binding]; other site
527001005057	active site
527001005058	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
527001005059	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001005060	active site
527001005061	phosphorylation site [posttranslational modification]
527001005062	intermolecular recognition site; other site
527001005063	dimerization interface [polypeptide binding]; other site
527001005064	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001005065	DNA binding site [nucleotide binding]
527001005066	sensor protein PhoQ; Provisional; Region: PRK10815
527001005067	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
527001005068	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
527001005069	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001005070	ATP binding site [chemical binding]; other site
527001005071	Mg2+ binding site [ion binding]; other site
527001005072	G-X-G motif; other site
527001005073	Uncharacterized conserved protein [Function unknown]; Region: COG2850
527001005074	Cupin domain; Region: Cupin_2; cl17218
527001005075	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
527001005076	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
527001005077	metal binding site [ion binding]; metal-binding site
527001005078	dimer interface [polypeptide binding]; other site
527001005079	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
527001005080	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001005081	Walker A/P-loop; other site
527001005082	ATP binding site [chemical binding]; other site
527001005083	Q-loop/lid; other site
527001005084	ABC transporter signature motif; other site
527001005085	Walker B; other site
527001005086	D-loop; other site
527001005087	H-loop/switch region; other site
527001005088	TOBE domain; Region: TOBE_2; pfam08402
527001005089	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
527001005090	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001005091	dimer interface [polypeptide binding]; other site
527001005092	conserved gate region; other site
527001005093	putative PBP binding loops; other site
527001005094	ABC-ATPase subunit interface; other site
527001005095	secreted effector protein SifA; Reviewed; Region: sifA; PRK09498
527001005096	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
527001005097	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001005098	dimer interface [polypeptide binding]; other site
527001005099	conserved gate region; other site
527001005100	putative PBP binding loops; other site
527001005101	ABC-ATPase subunit interface; other site
527001005102	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
527001005103	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
527001005104	NAD-dependent deacetylase; Provisional; Region: PRK00481
527001005105	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
527001005106	NAD+ binding site [chemical binding]; other site
527001005107	substrate binding site [chemical binding]; other site
527001005108	Zn binding site [ion binding]; other site
527001005109	fructokinase; Reviewed; Region: PRK09557
527001005110	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
527001005111	nucleotide binding site [chemical binding]; other site
527001005112	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
527001005113	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
527001005114	FtsX-like permease family; Region: FtsX; pfam02687
527001005115	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
527001005116	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
527001005117	Walker A/P-loop; other site
527001005118	ATP binding site [chemical binding]; other site
527001005119	Q-loop/lid; other site
527001005120	ABC transporter signature motif; other site
527001005121	Walker B; other site
527001005122	D-loop; other site
527001005123	H-loop/switch region; other site
527001005124	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
527001005125	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
527001005126	FtsX-like permease family; Region: FtsX; pfam02687
527001005127	transcription-repair coupling factor; Provisional; Region: PRK10689
527001005128	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
527001005129	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001005130	ATP binding site [chemical binding]; other site
527001005131	putative Mg++ binding site [ion binding]; other site
527001005132	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001005133	nucleotide binding region [chemical binding]; other site
527001005134	ATP-binding site [chemical binding]; other site
527001005135	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
527001005136	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
527001005137	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
527001005138	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
527001005139	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
527001005140	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
527001005141	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001005142	hypothetical protein; Provisional; Region: PRK11280
527001005143	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
527001005144	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001005145	hypothetical protein; Provisional; Region: PRK04940
527001005146	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
527001005147	beta-hexosaminidase; Provisional; Region: PRK05337
527001005148	thiamine kinase; Region: ycfN_thiK; TIGR02721
527001005149	thiamine kinase; Provisional; Region: thiK; PRK10271
527001005150	substrate binding site [chemical binding]; other site
527001005151	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
527001005152	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
527001005153	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
527001005154	putative dimer interface [polypeptide binding]; other site
527001005155	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
527001005156	nucleotide binding site/active site [active]
527001005157	HIT family signature motif; other site
527001005158	catalytic residue [active]
527001005159	potential frameshift: common BLAST hit: gi|197247500|ref|YP_002146838.1| ferric-rhodotorulic acid outer membrane transporter
527001005160	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
527001005161	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
527001005162	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
527001005163	active site turn [active]
527001005164	phosphorylation site [posttranslational modification]
527001005165	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
527001005166	active site
527001005167	DNA polymerase III subunit delta'; Validated; Region: PRK07993
527001005168	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
527001005169	thymidylate kinase; Validated; Region: tmk; PRK00698
527001005170	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
527001005171	TMP-binding site; other site
527001005172	ATP-binding site [chemical binding]; other site
527001005173	conserved hypothetical protein, YceG family; Region: TIGR00247
527001005174	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
527001005175	dimerization interface [polypeptide binding]; other site
527001005176	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
527001005177	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
527001005178	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001005179	catalytic residue [active]
527001005180	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
527001005181	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
527001005182	dimer interface [polypeptide binding]; other site
527001005183	active site
527001005184	acyl carrier protein; Provisional; Region: acpP; PRK00982
527001005185	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
527001005186	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
527001005187	NAD(P) binding site [chemical binding]; other site
527001005188	homotetramer interface [polypeptide binding]; other site
527001005189	homodimer interface [polypeptide binding]; other site
527001005190	active site
527001005191	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
527001005192	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
527001005193	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
527001005194	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
527001005195	dimer interface [polypeptide binding]; other site
527001005196	active site
527001005197	CoA binding pocket [chemical binding]; other site
527001005198	putative phosphate acyltransferase; Provisional; Region: PRK05331
527001005199	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
527001005200	hypothetical protein; Provisional; Region: PRK11193
527001005201	Maf-like protein; Region: Maf; pfam02545
527001005202	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
527001005203	active site
527001005204	dimer interface [polypeptide binding]; other site
527001005205	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
527001005206	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
527001005207	RNA binding surface [nucleotide binding]; other site
527001005208	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
527001005209	active site
527001005210	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
527001005211	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
527001005212	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
527001005213	homodimer interface [polypeptide binding]; other site
527001005214	oligonucleotide binding site [chemical binding]; other site
527001005215	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
527001005216	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001005217	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
527001005218	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
527001005219	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
527001005220	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
527001005221	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
527001005222	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
527001005223	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
527001005224	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
527001005225	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
527001005226	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
527001005227	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
527001005228	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
527001005229	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
527001005230	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
527001005231	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
527001005232	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
527001005233	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
527001005234	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
527001005235	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
527001005236	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
527001005237	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
527001005238	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
527001005239	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
527001005240	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
527001005241	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
527001005242	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
527001005243	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
527001005244	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
527001005245	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
527001005246	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
527001005247	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
527001005248	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
527001005249	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
527001005250	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
527001005251	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
527001005252	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
527001005253	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
527001005254	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
527001005255	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
527001005256	hypothetical protein; Provisional; Region: PRK11239
527001005257	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
527001005258	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
527001005259	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
527001005260	multidrug resistance protein MdtH; Provisional; Region: PRK11646
527001005261	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001005262	putative substrate translocation pore; other site
527001005263	glutaredoxin 2; Provisional; Region: PRK10387
527001005264	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
527001005265	C-terminal domain interface [polypeptide binding]; other site
527001005266	GSH binding site (G-site) [chemical binding]; other site
527001005267	catalytic residues [active]
527001005268	putative dimer interface [polypeptide binding]; other site
527001005269	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
527001005270	N-terminal domain interface [polypeptide binding]; other site
527001005271	lipoprotein; Provisional; Region: PRK10598
527001005272	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
527001005273	active site
527001005274	substrate binding pocket [chemical binding]; other site
527001005275	dimer interface [polypeptide binding]; other site
527001005276	DNA damage-inducible protein I; Provisional; Region: PRK10597
527001005277	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
527001005278	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
527001005279	hydroxyglutarate oxidase; Provisional; Region: PRK11728
527001005280	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
527001005281	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
527001005282	hypothetical protein; Provisional; Region: PRK03757
527001005283	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
527001005284	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
527001005285	active site residue [active]
527001005286	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
527001005287	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
527001005288	putative acyl-acceptor binding pocket; other site
527001005289	drug efflux system protein MdtG; Provisional; Region: PRK09874
527001005290	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001005291	putative substrate translocation pore; other site
527001005292	secY/secA suppressor protein; Provisional; Region: PRK11467
527001005293	lipoprotein; Provisional; Region: PRK10175
527001005294	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
527001005295	Ligand binding site; other site
527001005296	DXD motif; other site
527001005297	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
527001005298	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
527001005299	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
527001005300	Acyltransferase family; Region: Acyl_transf_3; pfam01757
527001005301	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
527001005302	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
527001005303	putative active site [active]
527001005304	catalytic site [active]
527001005305	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
527001005306	putative active site [active]
527001005307	catalytic site [active]
527001005308	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
527001005309	putative ADP-ribose binding site [chemical binding]; other site
527001005310	putative active site [active]
527001005311	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
527001005312	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
527001005313	major curlin subunit; Provisional; Region: csgA; PRK10051
527001005314	Curlin associated repeat; Region: Curlin_rpt; pfam07012
527001005315	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
527001005316	Curlin associated repeat; Region: Curlin_rpt; pfam07012
527001005317	Curlin associated repeat; Region: Curlin_rpt; pfam07012
527001005318	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
527001005319	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001005320	DNA binding residues [nucleotide binding]
527001005321	dimerization interface [polypeptide binding]; other site
527001005322	curli assembly protein CsgE; Provisional; Region: PRK10386
527001005323	curli assembly protein CsgF; Provisional; Region: PRK10050
527001005324	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
527001005325	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
527001005326	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
527001005327	putative hydrolase; Validated; Region: PRK09248
527001005328	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
527001005329	active site
527001005330	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
527001005331	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
527001005332	putative ligand binding site [chemical binding]; other site
527001005333	NAD binding site [chemical binding]; other site
527001005334	dimerization interface [polypeptide binding]; other site
527001005335	catalytic site [active]
527001005336	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
527001005337	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
527001005338	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
527001005339	putative sialic acid transporter; Provisional; Region: PRK12307
527001005340	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001005341	putative substrate translocation pore; other site
527001005342	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
527001005343	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
527001005344	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
527001005345	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
527001005346	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
527001005347	putative active site cavity [active]
527001005348	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
527001005349	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
527001005350	Na binding site [ion binding]; other site
527001005351	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
527001005352	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
527001005353	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
527001005354	putative active site [active]
527001005355	hypothetical protein; Provisional; Region: PRK10536
527001005356	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
527001005357	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
527001005358	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
527001005359	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
527001005360	Na binding site [ion binding]; other site
527001005361	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
527001005362	Predicted transcriptional regulator [Transcription]; Region: COG3905
527001005363	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
527001005364	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
527001005365	Glutamate binding site [chemical binding]; other site
527001005366	NAD binding site [chemical binding]; other site
527001005367	catalytic residues [active]
527001005368	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
527001005369	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
527001005370	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001005371	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
527001005372	General stress protein [General function prediction only]; Region: GsiB; COG3729
527001005373	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
527001005374	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
527001005375	hypothetical protein; Provisional; Region: PRK10174
527001005376	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
527001005377	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
527001005378	catalytic core [active]
527001005379	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
527001005380	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
527001005381	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
527001005382	catalytic residues [active]
527001005383	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
527001005384	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
527001005385	catalytic residues [active]
527001005386	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
527001005387	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
527001005388	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
527001005389	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
527001005390	DsbD alpha interface [polypeptide binding]; other site
527001005391	catalytic residues [active]
527001005392	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
527001005393	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
527001005394	HSP70 interaction site [polypeptide binding]; other site
527001005395	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
527001005396	substrate binding site [polypeptide binding]; other site
527001005397	dimer interface [polypeptide binding]; other site
527001005398	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
527001005399	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
527001005400	anti-adapter protein IraM; Provisional; Region: PRK09919
527001005401	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
527001005402	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
527001005403	Cupin domain; Region: Cupin_2; pfam07883
527001005404	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001005405	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001005406	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
527001005407	putative substrate translocation pore; other site
527001005408	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
527001005409	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
527001005410	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
527001005411	putative substrate binding pocket [chemical binding]; other site
527001005412	trimer interface [polypeptide binding]; other site
527001005413	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
527001005414	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
527001005415	putative active site [active]
527001005416	putative metal binding site [ion binding]; other site
527001005417	potential frameshift: common BLAST hit: gi|197250383|ref|YP_002145971.1| 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
527001005418	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
527001005419	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
527001005420	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
527001005421	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
527001005422	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
527001005423	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
527001005424	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
527001005425	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
527001005426	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
527001005427	active site
527001005428	homotetramer interface [polypeptide binding]; other site
527001005429	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
527001005430	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001005431	active site
527001005432	phosphorylation site [posttranslational modification]
527001005433	intermolecular recognition site; other site
527001005434	dimerization interface [polypeptide binding]; other site
527001005435	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001005436	DNA binding site [nucleotide binding]
527001005437	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
527001005438	HAMP domain; Region: HAMP; pfam00672
527001005439	dimerization interface [polypeptide binding]; other site
527001005440	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001005441	dimer interface [polypeptide binding]; other site
527001005442	phosphorylation site [posttranslational modification]
527001005443	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001005444	ATP binding site [chemical binding]; other site
527001005445	Mg2+ binding site [ion binding]; other site
527001005446	G-X-G motif; other site
527001005447	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
527001005448	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
527001005449	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
527001005450	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
527001005451	secreted effector protein PipB; Provisional; Region: PRK15197
527001005452	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
527001005453	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
527001005454	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
527001005455	PipA protein; Region: PipA; pfam07108
527001005456	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001005457	potential protein location (hypothetical protein TY21A_09330 [Salmonella enterica subsp. enterica serovar Typhi str. Ty21]) that overlaps RNA (tRNA-S)
527001005458	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
527001005459	YccA-like proteins; Region: YccA_like; cd10433
527001005460	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
527001005461	sulfur transfer protein TusE; Provisional; Region: PRK11508
527001005462	acylphosphatase; Provisional; Region: PRK14426
527001005463	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
527001005464	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001005465	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001005466	Cupin domain; Region: Cupin_2; cl17218
527001005467	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
527001005468	substrate binding site [chemical binding]; other site
527001005469	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
527001005470	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
527001005471	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
527001005472	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
527001005473	putative RNA binding site [nucleotide binding]; other site
527001005474	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001005475	S-adenosylmethionine binding site [chemical binding]; other site
527001005476	heat shock protein HspQ; Provisional; Region: PRK14129
527001005477	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
527001005478	hypothetical protein; Provisional; Region: PRK03641
527001005479	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
527001005480	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
527001005481	active site
527001005482	dimer interfaces [polypeptide binding]; other site
527001005483	catalytic residues [active]
527001005484	DNA helicase IV; Provisional; Region: helD; PRK11054
527001005485	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
527001005486	Part of AAA domain; Region: AAA_19; pfam13245
527001005487	Family description; Region: UvrD_C_2; pfam13538
527001005488	Predicted membrane protein [Function unknown]; Region: COG3304
527001005489	Domain of unknown function (DUF307); Region: DUF307; pfam03733
527001005490	Domain of unknown function (DUF307); Region: DUF307; pfam03733
527001005491	TIGR01666 family membrane protein; Region: YCCS
527001005492	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
527001005493	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
527001005494	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
527001005495	TfoX C-terminal domain; Region: TfoX_C; pfam04994
527001005496	cell division inhibitor SulA; Region: sula; TIGR00623
527001005497	outer membrane protein A; Reviewed; Region: PRK10808
527001005498	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
527001005499	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
527001005500	ligand binding site [chemical binding]; other site
527001005501	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
527001005502	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
527001005503	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
527001005504	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
527001005505	active site 1 [active]
527001005506	dimer interface [polypeptide binding]; other site
527001005507	active site 2 [active]
527001005508	ribosome modulation factor; Provisional; Region: PRK14563
527001005509	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
527001005510	Protein of unknown function (DUF330); Region: DUF330; pfam03886
527001005511	paraquat-inducible protein B; Provisional; Region: PRK10807
527001005512	mce related protein; Region: MCE; pfam02470
527001005513	mce related protein; Region: MCE; pfam02470
527001005514	mce related protein; Region: MCE; pfam02470
527001005515	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
527001005516	Paraquat-inducible protein A; Region: PqiA; pfam04403
527001005517	Paraquat-inducible protein A; Region: PqiA; pfam04403
527001005518	ABC transporter ATPase component; Reviewed; Region: PRK11147
527001005519	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001005520	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001005521	Walker A/P-loop; other site
527001005522	Walker A/P-loop; other site
527001005523	ATP binding site [chemical binding]; other site
527001005524	ATP binding site [chemical binding]; other site
527001005525	Q-loop/lid; other site
527001005526	Q-loop/lid; other site
527001005527	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
527001005528	ABC transporter signature motif; other site
527001005529	Walker B; other site
527001005530	D-loop; other site
527001005531	ABC transporter; Region: ABC_tran_2; pfam12848
527001005532	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
527001005533	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
527001005534	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
527001005535	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
527001005536	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001005537	S-adenosylmethionine binding site [chemical binding]; other site
527001005538	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
527001005539	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
527001005540	MOSC domain; Region: MOSC; pfam03473
527001005541	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
527001005542	catalytic loop [active]
527001005543	iron binding site [ion binding]; other site
527001005544	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
527001005545	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
527001005546	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
527001005547	quinone interaction residues [chemical binding]; other site
527001005548	active site
527001005549	catalytic residues [active]
527001005550	FMN binding site [chemical binding]; other site
527001005551	substrate binding site [chemical binding]; other site
527001005552	aminopeptidase N; Provisional; Region: pepN; PRK14015
527001005553	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
527001005554	active site
527001005555	Zn binding site [ion binding]; other site
527001005556	DinI-like family; Region: DinI; cl11630
527001005557	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
527001005558	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
527001005559	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
527001005560	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
527001005561	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
527001005562	Baseplate J-like protein; Region: Baseplate_J; cl01294
527001005563	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
527001005564	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
527001005565	HEPN domain; Region: HEPN; cl00824
527001005566	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
527001005567	virion protein; Provisional; Region: V; PHA02564
527001005568	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
527001005569	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
527001005570	Protein of unknown function (DUF4054); Region: DUF4054; pfam13262
527001005571	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834
527001005572	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
527001005573	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
527001005574	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
527001005575	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
527001005576	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
527001005577	Phage terminase large subunit; Region: Terminase_3; cl12054
527001005578	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
527001005579	Predicted chitinase [General function prediction only]; Region: COG3179
527001005580	Protein of unknown function (DUF754); Region: DUF754; pfam05449
527001005581	Antitermination protein; Region: Antiterm; pfam03589
527001005582	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
527001005583	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
527001005584	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
527001005585	DinI-like family; Region: DinI; pfam06183
527001005586	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
527001005587	Protein of unknown function (DUF550); Region: DUF550; pfam04447
527001005588	Methyltransferase domain; Region: Methyltransf_25; pfam13649
527001005589	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
527001005590	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
527001005591	putative replication protein; Provisional; Region: PRK12377
527001005592	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001005593	Walker A motif; other site
527001005594	ATP binding site [chemical binding]; other site
527001005595	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
527001005596	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
527001005597	primosomal protein DnaI; Provisional; Region: PRK02854
527001005598	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
527001005599	transcriptional repressor DicA; Reviewed; Region: PRK09706
527001005600	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001005601	non-specific DNA binding site [nucleotide binding]; other site
527001005602	salt bridge; other site
527001005603	sequence-specific DNA binding site [nucleotide binding]; other site
527001005604	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
527001005605	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
527001005606	phage recombination protein Bet; Region: bet_lambda; TIGR01913
527001005607	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
527001005608	DNA-sulfur modification-associated; Region: DndB; pfam14072
527001005609	DGQHR domain; Region: DGQHR; TIGR03187
527001005610	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
527001005611	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
527001005612	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
527001005613	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
527001005614	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
527001005615	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
527001005616	Int/Topo IB signature motif; other site
527001005617	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
527001005618	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
527001005619	active site
527001005620	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
527001005621	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
527001005622	potential frameshift: common BLAST hit: gi|197362872|ref|YP_002142509.1| diaminopropionate ammonia-lyase
527001005623	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
527001005624	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
527001005625	putative DNA binding site [nucleotide binding]; other site
527001005626	putative Zn2+ binding site [ion binding]; other site
527001005627	AsnC family; Region: AsnC_trans_reg; pfam01037
527001005628	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
527001005629	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
527001005630	putative dimer interface [polypeptide binding]; other site
527001005631	putative anticodon binding site; other site
527001005632	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
527001005633	homodimer interface [polypeptide binding]; other site
527001005634	motif 1; other site
527001005635	motif 2; other site
527001005636	active site
527001005637	motif 3; other site
527001005638	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
527001005639	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
527001005640	trimer interface [polypeptide binding]; other site
527001005641	eyelet of channel; other site
527001005642	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
527001005643	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001005644	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001005645	homodimer interface [polypeptide binding]; other site
527001005646	catalytic residue [active]
527001005647	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
527001005648	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
527001005649	Peptidase M15; Region: Peptidase_M15_3; cl01194
527001005650	murein L,D-transpeptidase; Provisional; Region: PRK10594
527001005651	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
527001005652	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
527001005653	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
527001005654	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
527001005655	P-loop containing region of AAA domain; Region: AAA_29; cl17516
527001005656	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
527001005657	condesin subunit E; Provisional; Region: PRK05256
527001005658	condesin subunit F; Provisional; Region: PRK05260
527001005659	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
527001005660	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001005661	S-adenosylmethionine binding site [chemical binding]; other site
527001005662	Uncharacterized conserved protein [Function unknown]; Region: COG1434
527001005663	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
527001005664	putative active site [active]
527001005665	hypothetical protein; Provisional; Region: PRK10593
527001005666	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
527001005667	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
527001005668	Ligand binding site; other site
527001005669	oligomer interface; other site
527001005670	hypothetical protein; Provisional; Region: PRK11827
527001005671	potential frameshift: common BLAST hit: gi|197362888|ref|YP_002142525.1| putative cytoplasmic protein
527001005672	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
527001005673	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
527001005674	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
527001005675	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
527001005676	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
527001005677	Walker A/P-loop; other site
527001005678	ATP binding site [chemical binding]; other site
527001005679	Q-loop/lid; other site
527001005680	ABC transporter signature motif; other site
527001005681	Walker B; other site
527001005682	D-loop; other site
527001005683	H-loop/switch region; other site
527001005684	ComEC family competence protein; Provisional; Region: PRK11539
527001005685	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
527001005686	Competence protein; Region: Competence; pfam03772
527001005687	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
527001005688	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
527001005689	IHF dimer interface [polypeptide binding]; other site
527001005690	IHF - DNA interface [nucleotide binding]; other site
527001005691	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
527001005692	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
527001005693	RNA binding site [nucleotide binding]; other site
527001005694	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
527001005695	RNA binding site [nucleotide binding]; other site
527001005696	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
527001005697	RNA binding site [nucleotide binding]; other site
527001005698	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
527001005699	RNA binding site [nucleotide binding]; other site
527001005700	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
527001005701	RNA binding site [nucleotide binding]; other site
527001005702	cytidylate kinase; Provisional; Region: cmk; PRK00023
527001005703	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
527001005704	CMP-binding site; other site
527001005705	The sites determining sugar specificity; other site
527001005706	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
527001005707	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
527001005708	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
527001005709	hinge; other site
527001005710	active site
527001005711	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
527001005712	homodimer interface [polypeptide binding]; other site
527001005713	substrate-cofactor binding pocket; other site
527001005714	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001005715	catalytic residue [active]
527001005716	Predicted membrane protein [Function unknown]; Region: COG2323
527001005717	uncharacterized domain; Region: TIGR00702
527001005718	YcaO-like family; Region: YcaO; pfam02624
527001005719	formate transporter; Provisional; Region: PRK10805
527001005720	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
527001005721	Pyruvate formate lyase 1; Region: PFL1; cd01678
527001005722	coenzyme A binding site [chemical binding]; other site
527001005723	active site
527001005724	catalytic residues [active]
527001005725	glycine loop; other site
527001005726	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
527001005727	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
527001005728	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001005729	FeS/SAM binding site; other site
527001005730	inner membrane transporter YjeM; Provisional; Region: PRK15238
527001005731	putative MFS family transporter protein; Provisional; Region: PRK03633
527001005732	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001005733	putative substrate translocation pore; other site
527001005734	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
527001005735	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
527001005736	4Fe-4S binding domain; Region: Fer4; pfam00037
527001005737	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
527001005738	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
527001005739	putative [Fe4-S4] binding site [ion binding]; other site
527001005740	putative molybdopterin cofactor binding site [chemical binding]; other site
527001005741	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
527001005742	putative molybdopterin cofactor binding site; other site
527001005743	seryl-tRNA synthetase; Provisional; Region: PRK05431
527001005744	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
527001005745	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
527001005746	dimer interface [polypeptide binding]; other site
527001005747	active site
527001005748	motif 1; other site
527001005749	motif 2; other site
527001005750	motif 3; other site
527001005751	recombination factor protein RarA; Reviewed; Region: PRK13342
527001005752	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001005753	Walker A motif; other site
527001005754	ATP binding site [chemical binding]; other site
527001005755	Walker B motif; other site
527001005756	arginine finger; other site
527001005757	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
527001005758	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
527001005759	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
527001005760	DNA translocase FtsK; Provisional; Region: PRK10263
527001005761	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
527001005762	DNA translocase FtsK; Provisional; Region: PRK10263
527001005763	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
527001005764	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
527001005765	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
527001005766	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
527001005767	putative DNA binding site [nucleotide binding]; other site
527001005768	putative Zn2+ binding site [ion binding]; other site
527001005769	AsnC family; Region: AsnC_trans_reg; pfam01037
527001005770	thioredoxin reductase; Provisional; Region: PRK10262
527001005771	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
527001005772	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001005773	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
527001005774	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
527001005775	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001005776	Walker A/P-loop; other site
527001005777	ATP binding site [chemical binding]; other site
527001005778	Q-loop/lid; other site
527001005779	ABC transporter signature motif; other site
527001005780	Walker B; other site
527001005781	D-loop; other site
527001005782	H-loop/switch region; other site
527001005783	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
527001005784	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
527001005785	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001005786	Walker A/P-loop; other site
527001005787	ATP binding site [chemical binding]; other site
527001005788	Q-loop/lid; other site
527001005789	ABC transporter signature motif; other site
527001005790	Walker B; other site
527001005791	D-loop; other site
527001005792	H-loop/switch region; other site
527001005793	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
527001005794	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
527001005795	rRNA binding site [nucleotide binding]; other site
527001005796	predicted 30S ribosome binding site; other site
527001005797	LysR family transcriptional regulator; Provisional; Region: PRK14997
527001005798	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001005799	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
527001005800	putative effector binding pocket; other site
527001005801	putative dimerization interface [polypeptide binding]; other site
527001005802	Pirin-related protein [General function prediction only]; Region: COG1741
527001005803	Pirin; Region: Pirin; pfam02678
527001005804	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
527001005805	Isochorismatase family; Region: Isochorismatase; pfam00857
527001005806	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
527001005807	catalytic triad [active]
527001005808	dimer interface [polypeptide binding]; other site
527001005809	conserved cis-peptide bond; other site
527001005810	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
527001005811	DNA binding site [nucleotide binding]
527001005812	active site
527001005813	Int/Topo IB signature motif; other site
527001005814	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
527001005815	Clp amino terminal domain; Region: Clp_N; pfam02861
527001005816	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001005817	Walker A motif; other site
527001005818	ATP binding site [chemical binding]; other site
527001005819	Walker B motif; other site
527001005820	arginine finger; other site
527001005821	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001005822	Walker A motif; other site
527001005823	ATP binding site [chemical binding]; other site
527001005824	Walker B motif; other site
527001005825	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
527001005826	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
527001005827	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
527001005828	DNA-binding site [nucleotide binding]; DNA binding site
527001005829	RNA-binding motif; other site
527001005830	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
527001005831	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
527001005832	Walker A/P-loop; other site
527001005833	ATP binding site [chemical binding]; other site
527001005834	Q-loop/lid; other site
527001005835	ABC transporter signature motif; other site
527001005836	Walker B; other site
527001005837	D-loop; other site
527001005838	H-loop/switch region; other site
527001005839	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
527001005840	FtsX-like permease family; Region: FtsX; pfam02687
527001005841	macrolide transporter subunit MacA; Provisional; Region: PRK11578
527001005842	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
527001005843	HlyD family secretion protein; Region: HlyD_3; pfam13437
527001005844	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
527001005845	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
527001005846	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
527001005847	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
527001005848	putative active site [active]
527001005849	putative metal-binding site [ion binding]; other site
527001005850	Predicted membrane protein [Function unknown]; Region: COG2431
527001005851	hybrid cluster protein; Provisional; Region: PRK05290
527001005852	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
527001005853	ACS interaction site; other site
527001005854	CODH interaction site; other site
527001005855	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
527001005856	hybrid metal cluster; other site
527001005857	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
527001005858	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
527001005859	FAD binding pocket [chemical binding]; other site
527001005860	FAD binding motif [chemical binding]; other site
527001005861	phosphate binding motif [ion binding]; other site
527001005862	beta-alpha-beta structure motif; other site
527001005863	NAD binding pocket [chemical binding]; other site
527001005864	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
527001005865	catalytic loop [active]
527001005866	iron binding site [ion binding]; other site
527001005867	pyruvate dehydrogenase; Provisional; Region: PRK09124
527001005868	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
527001005869	PYR/PP interface [polypeptide binding]; other site
527001005870	dimer interface [polypeptide binding]; other site
527001005871	tetramer interface [polypeptide binding]; other site
527001005872	TPP binding site [chemical binding]; other site
527001005873	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
527001005874	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
527001005875	TPP-binding site [chemical binding]; other site
527001005876	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
527001005877	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
527001005878	tetramer interface [polypeptide binding]; other site
527001005879	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001005880	catalytic residue [active]
527001005881	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
527001005882	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
527001005883	putative NAD(P) binding site [chemical binding]; other site
527001005884	putative active site [active]
527001005885	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
527001005886	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
527001005887	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
527001005888	NAD(P) binding site [chemical binding]; other site
527001005889	active site
527001005890	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
527001005891	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
527001005892	amidase catalytic site [active]
527001005893	Zn binding residues [ion binding]; other site
527001005894	substrate binding site [chemical binding]; other site
527001005895	hypothetical protein; Provisional; Region: PRK02877
527001005896	putative lipoprotein; Provisional; Region: PRK10533
527001005897	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
527001005898	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001005899	Walker A/P-loop; other site
527001005900	ATP binding site [chemical binding]; other site
527001005901	Q-loop/lid; other site
527001005902	ABC transporter signature motif; other site
527001005903	Walker B; other site
527001005904	D-loop; other site
527001005905	H-loop/switch region; other site
527001005906	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
527001005907	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001005908	substrate binding pocket [chemical binding]; other site
527001005909	membrane-bound complex binding site; other site
527001005910	hinge residues; other site
527001005911	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
527001005912	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001005913	dimer interface [polypeptide binding]; other site
527001005914	conserved gate region; other site
527001005915	putative PBP binding loops; other site
527001005916	ABC-ATPase subunit interface; other site
527001005917	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001005918	dimer interface [polypeptide binding]; other site
527001005919	conserved gate region; other site
527001005920	putative PBP binding loops; other site
527001005921	ABC-ATPase subunit interface; other site
527001005922	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
527001005923	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001005924	substrate binding pocket [chemical binding]; other site
527001005925	membrane-bound complex binding site; other site
527001005926	hinge residues; other site
527001005927	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
527001005928	Sulfatase; Region: Sulfatase; cl17466
527001005929	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
527001005930	active site
527001005931	P-loop; other site
527001005932	phosphorylation site [posttranslational modification]
527001005933	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
527001005934	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
527001005935	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001005936	S-adenosylmethionine binding site [chemical binding]; other site
527001005937	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
527001005938	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
527001005939	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001005940	dimer interface [polypeptide binding]; other site
527001005941	conserved gate region; other site
527001005942	putative PBP binding loops; other site
527001005943	ABC-ATPase subunit interface; other site
527001005944	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001005945	dimer interface [polypeptide binding]; other site
527001005946	conserved gate region; other site
527001005947	putative PBP binding loops; other site
527001005948	ABC-ATPase subunit interface; other site
527001005949	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
527001005950	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001005951	Walker A/P-loop; other site
527001005952	ATP binding site [chemical binding]; other site
527001005953	Q-loop/lid; other site
527001005954	ABC transporter signature motif; other site
527001005955	Walker B; other site
527001005956	D-loop; other site
527001005957	H-loop/switch region; other site
527001005958	TOBE domain; Region: TOBE_2; pfam08402
527001005959	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
527001005960	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
527001005961	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
527001005962	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
527001005963	RimK-like ATP-grasp domain; Region: RimK; pfam08443
527001005964	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
527001005965	dimer interface [polypeptide binding]; other site
527001005966	FMN binding site [chemical binding]; other site
527001005967	NADPH bind site [chemical binding]; other site
527001005968	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
527001005969	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
527001005970	GSH binding site [chemical binding]; other site
527001005971	catalytic residues [active]
527001005972	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
527001005973	putative transporter; Provisional; Region: PRK04972
527001005974	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
527001005975	TrkA-C domain; Region: TrkA_C; pfam02080
527001005976	TrkA-C domain; Region: TrkA_C; pfam02080
527001005977	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
527001005978	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
527001005979	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001005980	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
527001005981	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001005982	putative substrate translocation pore; other site
527001005983	Major Facilitator Superfamily; Region: MFS_1; pfam07690
527001005984	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
527001005985	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001005986	active site
527001005987	motif I; other site
527001005988	motif II; other site
527001005989	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001005990	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
527001005991	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001005992	putative substrate translocation pore; other site
527001005993	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
527001005994	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
527001005995	active site
527001005996	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
527001005997	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
527001005998	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001005999	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
527001006000	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
527001006001	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
527001006002	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
527001006003	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
527001006004	putative C-terminal domain interface [polypeptide binding]; other site
527001006005	putative GSH binding site (G-site) [chemical binding]; other site
527001006006	putative dimer interface [polypeptide binding]; other site
527001006007	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
527001006008	putative N-terminal domain interface [polypeptide binding]; other site
527001006009	putative dimer interface [polypeptide binding]; other site
527001006010	putative substrate binding pocket (H-site) [chemical binding]; other site
527001006011	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
527001006012	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
527001006013	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
527001006014	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
527001006015	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
527001006016	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001006017	FeS/SAM binding site; other site
527001006018	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
527001006019	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
527001006020	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001006021	dimer interface [polypeptide binding]; other site
527001006022	conserved gate region; other site
527001006023	putative PBP binding loops; other site
527001006024	ABC-ATPase subunit interface; other site
527001006025	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
527001006026	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001006027	dimer interface [polypeptide binding]; other site
527001006028	conserved gate region; other site
527001006029	putative PBP binding loops; other site
527001006030	ABC-ATPase subunit interface; other site
527001006031	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
527001006032	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
527001006033	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
527001006034	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001006035	Walker A/P-loop; other site
527001006036	ATP binding site [chemical binding]; other site
527001006037	Q-loop/lid; other site
527001006038	ABC transporter signature motif; other site
527001006039	Walker B; other site
527001006040	D-loop; other site
527001006041	H-loop/switch region; other site
527001006042	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
527001006043	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001006044	Walker A/P-loop; other site
527001006045	ATP binding site [chemical binding]; other site
527001006046	Q-loop/lid; other site
527001006047	ABC transporter signature motif; other site
527001006048	Walker B; other site
527001006049	D-loop; other site
527001006050	H-loop/switch region; other site
527001006051	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
527001006052	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
527001006053	catalytic nucleophile [active]
527001006054	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
527001006055	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
527001006056	dimer interface [polypeptide binding]; other site
527001006057	putative functional site; other site
527001006058	putative MPT binding site; other site
527001006059	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
527001006060	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
527001006061	ATP binding site [chemical binding]; other site
527001006062	substrate interface [chemical binding]; other site
527001006063	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
527001006064	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001006065	FeS/SAM binding site; other site
527001006066	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
527001006067	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
527001006068	dimer interface [polypeptide binding]; other site
527001006069	active site
527001006070	glycine loop; other site
527001006071	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
527001006072	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001006073	active site
527001006074	motif I; other site
527001006075	motif II; other site
527001006076	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001006077	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
527001006078	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
527001006079	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
527001006080	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001006081	Walker A/P-loop; other site
527001006082	ATP binding site [chemical binding]; other site
527001006083	ABC transporter signature motif; other site
527001006084	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
527001006085	Walker B; other site
527001006086	ABC transporter; Region: ABC_tran_2; pfam12848
527001006087	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
527001006088	L,D-transpeptidase; Provisional; Region: PRK10260
527001006089	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
527001006090	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
527001006091	transmembrane helices; other site
527001006092	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
527001006093	manganese transport regulator MntR; Provisional; Region: PRK11050
527001006094	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
527001006095	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
527001006096	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
527001006097	Sulfatase; Region: Sulfatase; pfam00884
527001006098	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001006099	outer membrane protein X; Provisional; Region: ompX; PRK09408
527001006100	threonine and homoserine efflux system; Provisional; Region: PRK10532
527001006101	EamA-like transporter family; Region: EamA; pfam00892
527001006102	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
527001006103	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
527001006104	dimerization interface [polypeptide binding]; other site
527001006105	DPS ferroxidase diiron center [ion binding]; other site
527001006106	ion pore; other site
527001006107	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
527001006108	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001006109	substrate binding pocket [chemical binding]; other site
527001006110	membrane-bound complex binding site; other site
527001006111	hinge residues; other site
527001006112	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
527001006113	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001006114	dimer interface [polypeptide binding]; other site
527001006115	conserved gate region; other site
527001006116	putative PBP binding loops; other site
527001006117	ABC-ATPase subunit interface; other site
527001006118	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
527001006119	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
527001006120	Walker A/P-loop; other site
527001006121	ATP binding site [chemical binding]; other site
527001006122	Q-loop/lid; other site
527001006123	ABC transporter signature motif; other site
527001006124	Walker B; other site
527001006125	D-loop; other site
527001006126	H-loop/switch region; other site
527001006127	putative mechanosensitive channel protein; Provisional; Region: PRK11465
527001006128	Mechanosensitive ion channel; Region: MS_channel; pfam00924
527001006129	potential frameshift: common BLAST hit: gi|207856262|ref|YP_002242913.1| putative SAM-dependent methyltransferase
527001006130	hypothetical protein; Provisional; Region: PRK11019
527001006131	hypothetical protein; Provisional; Region: PRK10259
527001006132	potential frameshift: common BLAST hit: gi|194445812|ref|YP_002040057.1| glycosyl transferase family protein
527001006133	potential frameshift: common BLAST hit: gi|197250514|ref|YP_002145777.1| ATP-dependent DNA helicase DinG
527001006134	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
527001006135	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
527001006136	ATP binding site [chemical binding]; other site
527001006137	Mg++ binding site [ion binding]; other site
527001006138	motif III; other site
527001006139	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001006140	nucleotide binding region [chemical binding]; other site
527001006141	ATP-binding site [chemical binding]; other site
527001006142	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
527001006143	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001006144	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
527001006145	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
527001006146	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
527001006147	HlyD family secretion protein; Region: HlyD_3; pfam13437
527001006148	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
527001006149	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
527001006150	Walker A/P-loop; other site
527001006151	ATP binding site [chemical binding]; other site
527001006152	Q-loop/lid; other site
527001006153	ABC transporter signature motif; other site
527001006154	Walker B; other site
527001006155	D-loop; other site
527001006156	H-loop/switch region; other site
527001006157	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
527001006158	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
527001006159	Walker A/P-loop; other site
527001006160	ATP binding site [chemical binding]; other site
527001006161	Q-loop/lid; other site
527001006162	ABC transporter signature motif; other site
527001006163	Walker B; other site
527001006164	D-loop; other site
527001006165	H-loop/switch region; other site
527001006166	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
527001006167	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
527001006168	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
527001006169	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
527001006170	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
527001006171	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
527001006172	putative catalytic site [active]
527001006173	putative metal binding site [ion binding]; other site
527001006174	putative phosphate binding site [ion binding]; other site
527001006175	cardiolipin synthase 2; Provisional; Region: PRK11263
527001006176	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
527001006177	putative active site [active]
527001006178	catalytic site [active]
527001006179	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
527001006180	putative active site [active]
527001006181	catalytic site [active]
527001006182	Predicted integral membrane protein [Function unknown]; Region: COG0392
527001006183	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
527001006184	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
527001006185	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
527001006186	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
527001006187	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
527001006188	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
527001006189	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
527001006190	MoaE homodimer interface [polypeptide binding]; other site
527001006191	MoaD interaction [polypeptide binding]; other site
527001006192	active site residues [active]
527001006193	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
527001006194	MoaE interaction surface [polypeptide binding]; other site
527001006195	MoeB interaction surface [polypeptide binding]; other site
527001006196	thiocarboxylated glycine; other site
527001006197	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
527001006198	trimer interface [polypeptide binding]; other site
527001006199	dimer interface [polypeptide binding]; other site
527001006200	putative active site [active]
527001006201	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
527001006202	MPT binding site; other site
527001006203	trimer interface [polypeptide binding]; other site
527001006204	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
527001006205	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001006206	FeS/SAM binding site; other site
527001006207	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
527001006208	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
527001006209	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
527001006210	putative substrate binding pocket [chemical binding]; other site
527001006211	dimer interface [polypeptide binding]; other site
527001006212	phosphate binding site [ion binding]; other site
527001006213	potential frameshift: common BLAST hit: gi|194445572|ref|YP_002040035.1| leucine-rich repeat protein
527001006214	excinuclease ABC subunit B; Provisional; Region: PRK05298
527001006215	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001006216	ATP binding site [chemical binding]; other site
527001006217	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001006218	nucleotide binding region [chemical binding]; other site
527001006219	ATP-binding site [chemical binding]; other site
527001006220	Ultra-violet resistance protein B; Region: UvrB; pfam12344
527001006221	UvrB/uvrC motif; Region: UVR; pfam02151
527001006222	AAA domain; Region: AAA_26; pfam13500
527001006223	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
527001006224	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
527001006225	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001006226	S-adenosylmethionine binding site [chemical binding]; other site
527001006227	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
527001006228	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
527001006229	substrate-cofactor binding pocket; other site
527001006230	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001006231	catalytic residue [active]
527001006232	biotin synthase; Provisional; Region: PRK15108
527001006233	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001006234	FeS/SAM binding site; other site
527001006235	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
527001006236	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
527001006237	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
527001006238	inhibitor-cofactor binding pocket; inhibition site
527001006239	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001006240	catalytic residue [active]
527001006241	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
527001006242	substrate binding site [chemical binding]; other site
527001006243	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
527001006244	active sites [active]
527001006245	tetramer interface [polypeptide binding]; other site
527001006246	urocanate hydratase; Provisional; Region: PRK05414
527001006247	histidine utilization repressor; Provisional; Region: PRK14999
527001006248	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001006249	DNA-binding site [nucleotide binding]; DNA binding site
527001006250	UTRA domain; Region: UTRA; pfam07702
527001006251	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
527001006252	putative active site [active]
527001006253	putative metal binding site [ion binding]; other site
527001006254	imidazolonepropionase; Validated; Region: PRK09356
527001006255	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
527001006256	active site
527001006257	acyl-CoA thioesterase; Provisional; Region: PRK10531
527001006258	putative pectinesterase; Region: PLN02432; cl01911
527001006259	6-phosphogluconolactonase; Provisional; Region: PRK11028
527001006260	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
527001006261	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001006262	active site
527001006263	motif I; other site
527001006264	motif II; other site
527001006265	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001006266	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
527001006267	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001006268	Walker A/P-loop; other site
527001006269	ATP binding site [chemical binding]; other site
527001006270	Q-loop/lid; other site
527001006271	ABC transporter signature motif; other site
527001006272	Walker B; other site
527001006273	D-loop; other site
527001006274	H-loop/switch region; other site
527001006275	molybdenum-pterin binding domain; Region: Mop; TIGR00638
527001006276	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
527001006277	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001006278	dimer interface [polypeptide binding]; other site
527001006279	conserved gate region; other site
527001006280	putative PBP binding loops; other site
527001006281	ABC-ATPase subunit interface; other site
527001006282	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
527001006283	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001006284	substrate binding pocket [chemical binding]; other site
527001006285	membrane-bound complex binding site; other site
527001006286	hinge residues; other site
527001006287	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
527001006288	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
527001006289	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
527001006290	molybdenum-pterin binding domain; Region: Mop; TIGR00638
527001006291	TOBE domain; Region: TOBE; pfam03459
527001006292	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
527001006293	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001006294	Walker A/P-loop; other site
527001006295	ATP binding site [chemical binding]; other site
527001006296	Q-loop/lid; other site
527001006297	ABC transporter signature motif; other site
527001006298	Walker B; other site
527001006299	D-loop; other site
527001006300	H-loop/switch region; other site
527001006301	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001006302	Walker A/P-loop; other site
527001006303	ATP binding site [chemical binding]; other site
527001006304	Q-loop/lid; other site
527001006305	ABC transporter signature motif; other site
527001006306	Walker B; other site
527001006307	D-loop; other site
527001006308	H-loop/switch region; other site
527001006309	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
527001006310	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
527001006311	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
527001006312	NAD binding site [chemical binding]; other site
527001006313	homodimer interface [polypeptide binding]; other site
527001006314	active site
527001006315	substrate binding site [chemical binding]; other site
527001006316	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
527001006317	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
527001006318	dimer interface [polypeptide binding]; other site
527001006319	active site
527001006320	galactokinase; Provisional; Region: PRK05101
527001006321	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
527001006322	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
527001006323	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
527001006324	active site
527001006325	catalytic residues [active]
527001006326	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
527001006327	catalytic core [active]
527001006328	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
527001006329	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
527001006330	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
527001006331	Walker A/P-loop; other site
527001006332	ATP binding site [chemical binding]; other site
527001006333	Q-loop/lid; other site
527001006334	ABC transporter signature motif; other site
527001006335	Walker B; other site
527001006336	D-loop; other site
527001006337	H-loop/switch region; other site
527001006338	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
527001006339	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
527001006340	dimer interface [polypeptide binding]; other site
527001006341	putative PBP binding regions; other site
527001006342	ABC-ATPase subunit  interface; other site
527001006343	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
527001006344	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
527001006345	YbgS-like protein; Region: YbgS; pfam13985
527001006346	zinc transporter ZitB; Provisional; Region: PRK03557
527001006347	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
527001006348	quinolinate synthetase; Provisional; Region: PRK09375
527001006349	tol-pal system protein YbgF; Provisional; Region: PRK10803
527001006350	Tetratricopeptide repeat; Region: TPR_6; pfam13174
527001006351	Tetratricopeptide repeat; Region: TPR_6; pfam13174
527001006352	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
527001006353	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
527001006354	ligand binding site [chemical binding]; other site
527001006355	translocation protein TolB; Provisional; Region: tolB; PRK03629
527001006356	TolB amino-terminal domain; Region: TolB_N; pfam04052
527001006357	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
527001006358	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
527001006359	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
527001006360	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
527001006361	TolA C-terminal; Region: TolA; pfam06519
527001006362	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
527001006363	colicin uptake protein TolR; Provisional; Region: PRK11024
527001006364	colicin uptake protein TolQ; Provisional; Region: PRK10801
527001006365	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
527001006366	active site
527001006367	hypothetical protein; Provisional; Region: PRK10588
527001006368	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
527001006369	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
527001006370	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
527001006371	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
527001006372	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
527001006373	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
527001006374	CoA binding domain; Region: CoA_binding; smart00881
527001006375	CoA-ligase; Region: Ligase_CoA; pfam00549
527001006376	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
527001006377	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
527001006378	CoA-ligase; Region: Ligase_CoA; pfam00549
527001006379	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
527001006380	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
527001006381	E3 interaction surface; other site
527001006382	lipoyl attachment site [posttranslational modification]; other site
527001006383	e3 binding domain; Region: E3_binding; pfam02817
527001006384	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
527001006385	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
527001006386	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
527001006387	TPP-binding site [chemical binding]; other site
527001006388	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
527001006389	dimer interface [polypeptide binding]; other site
527001006390	PYR/PP interface [polypeptide binding]; other site
527001006391	TPP binding site [chemical binding]; other site
527001006392	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
527001006393	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
527001006394	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
527001006395	L-aspartate oxidase; Provisional; Region: PRK06175
527001006396	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
527001006397	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
527001006398	SdhC subunit interface [polypeptide binding]; other site
527001006399	proximal heme binding site [chemical binding]; other site
527001006400	cardiolipin binding site; other site
527001006401	Iron-sulfur protein interface; other site
527001006402	proximal quinone binding site [chemical binding]; other site
527001006403	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
527001006404	Iron-sulfur protein interface; other site
527001006405	proximal quinone binding site [chemical binding]; other site
527001006406	SdhD (CybS) interface [polypeptide binding]; other site
527001006407	proximal heme binding site [chemical binding]; other site
527001006408	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
527001006409	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
527001006410	dimer interface [polypeptide binding]; other site
527001006411	active site
527001006412	citrylCoA binding site [chemical binding]; other site
527001006413	NADH binding [chemical binding]; other site
527001006414	cationic pore residues; other site
527001006415	oxalacetate/citrate binding site [chemical binding]; other site
527001006416	coenzyme A binding site [chemical binding]; other site
527001006417	catalytic triad [active]
527001006418	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
527001006419	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
527001006420	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
527001006421	endonuclease VIII; Provisional; Region: PRK10445
527001006422	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
527001006423	DNA binding site [nucleotide binding]
527001006424	catalytic residue [active]
527001006425	putative catalytic residues [active]
527001006426	H2TH interface [polypeptide binding]; other site
527001006427	intercalation triad [nucleotide binding]; other site
527001006428	substrate specificity determining residue; other site
527001006429	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
527001006430	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
527001006431	potential frameshift: common BLAST hit: gi|194447526|ref|YP_002044757.1| putative glycosyl transferase
527001006432	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
527001006433	active site
527001006434	potential frameshift: common BLAST hit: gi|16764094|ref|NP_459709.1| putative glycosyltransferase
527001006435	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
527001006436	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
527001006437	Walker A/P-loop; other site
527001006438	ATP binding site [chemical binding]; other site
527001006439	Q-loop/lid; other site
527001006440	ABC transporter signature motif; other site
527001006441	Walker B; other site
527001006442	D-loop; other site
527001006443	H-loop/switch region; other site
527001006444	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
527001006445	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
527001006446	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
527001006447	putative ADP-binding pocket [chemical binding]; other site
527001006448	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
527001006449	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
527001006450	active site
527001006451	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
527001006452	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
527001006453	UDP-galactopyranose mutase; Region: GLF; pfam03275
527001006454	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
527001006455	active site
527001006456	DNA binding site [nucleotide binding]
527001006457	Int/Topo IB signature motif; other site
527001006458	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
527001006459	putative active site [active]
527001006460	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
527001006461	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
527001006462	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
527001006463	Uncharacterized conserved protein [Function unknown]; Region: COG0327
527001006464	metal-binding protein; Provisional; Region: PRK10799
527001006465	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
527001006466	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001006467	putative substrate translocation pore; other site
527001006468	POT family; Region: PTR2; pfam00854
527001006469	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
527001006470	DNA photolyase; Region: DNA_photolyase; pfam00875
527001006471	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
527001006472	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
527001006473	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
527001006474	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
527001006475	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
527001006476	sensor protein KdpD; Provisional; Region: PRK10490
527001006477	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
527001006478	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
527001006479	Ligand Binding Site [chemical binding]; other site
527001006480	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
527001006481	GAF domain; Region: GAF_3; pfam13492
527001006482	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001006483	dimer interface [polypeptide binding]; other site
527001006484	phosphorylation site [posttranslational modification]
527001006485	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001006486	ATP binding site [chemical binding]; other site
527001006487	Mg2+ binding site [ion binding]; other site
527001006488	G-X-G motif; other site
527001006489	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
527001006490	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001006491	active site
527001006492	phosphorylation site [posttranslational modification]
527001006493	intermolecular recognition site; other site
527001006494	dimerization interface [polypeptide binding]; other site
527001006495	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001006496	DNA binding site [nucleotide binding]
527001006497	putrescine transporter; Provisional; Region: potE; PRK10655
527001006498	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
527001006499	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
527001006500	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
527001006501	active site
527001006502	substrate binding site [chemical binding]; other site
527001006503	metal binding site [ion binding]; metal-binding site
527001006504	replication initiation regulator SeqA; Provisional; Region: PRK11187
527001006505	acyl-CoA esterase; Provisional; Region: PRK10673
527001006506	PGAP1-like protein; Region: PGAP1; pfam07819
527001006507	LexA regulated protein; Provisional; Region: PRK11675
527001006508	flavodoxin FldA; Validated; Region: PRK09267
527001006509	ferric uptake regulator; Provisional; Region: fur; PRK09462
527001006510	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
527001006511	metal binding site 2 [ion binding]; metal-binding site
527001006512	putative DNA binding helix; other site
527001006513	metal binding site 1 [ion binding]; metal-binding site
527001006514	dimer interface [polypeptide binding]; other site
527001006515	structural Zn2+ binding site [ion binding]; other site
527001006516	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001006517	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001006518	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
527001006519	putative dimerization interface [polypeptide binding]; other site
527001006520	tricarballylate dehydrogenase; Validated; Region: PRK08274
527001006521	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
527001006522	tricarballylate utilization protein B; Provisional; Region: PRK15033
527001006523	citrate-proton symporter; Provisional; Region: PRK15075
527001006524	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001006525	putative substrate translocation pore; other site
527001006526	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
527001006527	YbfN-like lipoprotein; Region: YbfN; pfam13982
527001006528	outer membrane porin, OprD family; Region: OprD; pfam03573
527001006529	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
527001006530	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
527001006531	active site
527001006532	HIGH motif; other site
527001006533	nucleotide binding site [chemical binding]; other site
527001006534	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
527001006535	KMSKS motif; other site
527001006536	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
527001006537	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
527001006538	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
527001006539	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
527001006540	active site turn [active]
527001006541	phosphorylation site [posttranslational modification]
527001006542	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
527001006543	HPr interaction site; other site
527001006544	glycerol kinase (GK) interaction site [polypeptide binding]; other site
527001006545	active site
527001006546	phosphorylation site [posttranslational modification]
527001006547	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
527001006548	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
527001006549	active site
527001006550	trimer interface [polypeptide binding]; other site
527001006551	allosteric site; other site
527001006552	active site lid [active]
527001006553	hexamer (dimer of trimers) interface [polypeptide binding]; other site
527001006554	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
527001006555	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
527001006556	active site
527001006557	dimer interface [polypeptide binding]; other site
527001006558	MarR family; Region: MarR; pfam01047
527001006559	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
527001006560	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
527001006561	nucleotide binding site [chemical binding]; other site
527001006562	UMP phosphatase; Provisional; Region: PRK10444
527001006563	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001006564	active site
527001006565	motif I; other site
527001006566	motif II; other site
527001006567	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001006568	asparagine synthetase B; Provisional; Region: asnB; PRK09431
527001006569	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
527001006570	active site
527001006571	dimer interface [polypeptide binding]; other site
527001006572	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
527001006573	Ligand Binding Site [chemical binding]; other site
527001006574	Molecular Tunnel; other site
527001006575	potential protein location (hypothetical protein TY21A_11160 [Salmonella enterica subsp. enterica serovar Typhi str. Ty21]) that overlaps RNA (tRNA-Q)
527001006576	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
527001006577	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
527001006578	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
527001006579	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
527001006580	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001006581	FeS/SAM binding site; other site
527001006582	TRAM domain; Region: TRAM; pfam01938
527001006583	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
527001006584	PhoH-like protein; Region: PhoH; pfam02562
527001006585	metal-binding heat shock protein; Provisional; Region: PRK00016
527001006586	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
527001006587	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
527001006588	Transporter associated domain; Region: CorC_HlyC; smart01091
527001006589	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
527001006590	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
527001006591	putative active site [active]
527001006592	catalytic triad [active]
527001006593	putative dimer interface [polypeptide binding]; other site
527001006594	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
527001006595	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001006596	substrate binding pocket [chemical binding]; other site
527001006597	membrane-bound complex binding site; other site
527001006598	hinge residues; other site
527001006599	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
527001006600	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001006601	dimer interface [polypeptide binding]; other site
527001006602	conserved gate region; other site
527001006603	putative PBP binding loops; other site
527001006604	ABC-ATPase subunit interface; other site
527001006605	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
527001006606	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001006607	dimer interface [polypeptide binding]; other site
527001006608	conserved gate region; other site
527001006609	putative PBP binding loops; other site
527001006610	ABC-ATPase subunit interface; other site
527001006611	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
527001006612	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
527001006613	Walker A/P-loop; other site
527001006614	ATP binding site [chemical binding]; other site
527001006615	Q-loop/lid; other site
527001006616	ABC transporter signature motif; other site
527001006617	Walker B; other site
527001006618	D-loop; other site
527001006619	H-loop/switch region; other site
527001006620	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
527001006621	active site
527001006622	tetramer interface [polypeptide binding]; other site
527001006623	hypothetical protein; Provisional; Region: PRK11032
527001006624	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
527001006625	Propionate catabolism activator; Region: PrpR_N; pfam06506
527001006626	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
527001006627	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001006628	Walker A motif; other site
527001006629	ATP binding site [chemical binding]; other site
527001006630	Walker B motif; other site
527001006631	arginine finger; other site
527001006632	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
527001006633	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
527001006634	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
527001006635	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
527001006636	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
527001006637	HIGH motif; other site
527001006638	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
527001006639	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
527001006640	active site
527001006641	KMSKS motif; other site
527001006642	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
527001006643	tRNA binding surface [nucleotide binding]; other site
527001006644	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
527001006645	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
527001006646	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
527001006647	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
527001006648	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
527001006649	active site
527001006650	(T/H)XGH motif; other site
527001006651	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
527001006652	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001006653	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001006654	homodimer interface [polypeptide binding]; other site
527001006655	catalytic residue [active]
527001006656	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
527001006657	catalytic core [active]
527001006658	ribosome-associated protein; Provisional; Region: PRK11538
527001006659	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
527001006660	penicillin-binding protein 2; Provisional; Region: PRK10795
527001006661	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
527001006662	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
527001006663	cell wall shape-determining protein; Provisional; Region: PRK10794
527001006664	rare lipoprotein A; Provisional; Region: PRK10672
527001006665	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
527001006666	Sporulation related domain; Region: SPOR; pfam05036
527001006667	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
527001006668	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
527001006669	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
527001006670	hypothetical protein; Provisional; Region: PRK04998
527001006671	lipoate-protein ligase B; Provisional; Region: PRK14342
527001006672	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
527001006673	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001006674	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
527001006675	substrate binding pocket [chemical binding]; other site
527001006676	dimerization interface [polypeptide binding]; other site
527001006677	lipoyl synthase; Provisional; Region: PRK05481
527001006678	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001006679	FeS/SAM binding site; other site
527001006680	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
527001006681	Predicted amidohydrolase [General function prediction only]; Region: COG0388
527001006682	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
527001006683	putative active site [active]
527001006684	catalytic triad [active]
527001006685	putative dimer interface [polypeptide binding]; other site
527001006686	chromosome condensation membrane protein; Provisional; Region: PRK14196
527001006687	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
527001006688	DNA-binding site [nucleotide binding]; DNA binding site
527001006689	RNA-binding motif; other site
527001006690	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
527001006691	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
527001006692	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
527001006693	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
527001006694	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001006695	active site
527001006696	phosphorylation site [posttranslational modification]
527001006697	intermolecular recognition site; other site
527001006698	dimerization interface [polypeptide binding]; other site
527001006699	Transcriptional regulator; Region: CitT; pfam12431
527001006700	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
527001006701	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
527001006702	putative active site [active]
527001006703	heme pocket [chemical binding]; other site
527001006704	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001006705	ATP binding site [chemical binding]; other site
527001006706	Mg2+ binding site [ion binding]; other site
527001006707	G-X-G motif; other site
527001006708	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
527001006709	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
527001006710	putative active site [active]
527001006711	(T/H)XGH motif; other site
527001006712	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
527001006713	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
527001006714	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
527001006715	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
527001006716	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; cl01498
527001006717	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
527001006718	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
527001006719	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
527001006720	transmembrane helices; other site
527001006721	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
527001006722	B1 nucleotide binding pocket [chemical binding]; other site
527001006723	B2 nucleotide binding pocket [chemical binding]; other site
527001006724	CAS motifs; other site
527001006725	active site
527001006726	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
527001006727	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
527001006728	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
527001006729	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
527001006730	NAD binding site [chemical binding]; other site
527001006731	catalytic Zn binding site [ion binding]; other site
527001006732	structural Zn binding site [ion binding]; other site
527001006733	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
527001006734	Ligand Binding Site [chemical binding]; other site
527001006735	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
527001006736	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
527001006737	4Fe-4S binding domain; Region: Fer4; cl02805
527001006738	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
527001006739	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
527001006740	putative [4Fe-4S] binding site [ion binding]; other site
527001006741	putative molybdopterin cofactor binding site [chemical binding]; other site
527001006742	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
527001006743	molybdopterin cofactor binding site; other site
527001006744	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
527001006745	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001006746	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
527001006747	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
527001006748	catalytic residue [active]
527001006749	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
527001006750	catalytic residues [active]
527001006751	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
527001006752	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001006753	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
527001006754	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
527001006755	dimer interface [polypeptide binding]; other site
527001006756	decamer (pentamer of dimers) interface [polypeptide binding]; other site
527001006757	catalytic triad [active]
527001006758	peroxidatic and resolving cysteines [active]
527001006759	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
527001006760	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
527001006761	dimerization domain [polypeptide binding]; other site
527001006762	dimer interface [polypeptide binding]; other site
527001006763	catalytic residues [active]
527001006764	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
527001006765	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001006766	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
527001006767	dimerization interface [polypeptide binding]; other site
527001006768	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
527001006769	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
527001006770	Active Sites [active]
527001006771	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
527001006772	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
527001006773	ParB-like nuclease domain; Region: ParBc; pfam02195
527001006774	methionine aminotransferase; Validated; Region: PRK09082
527001006775	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001006776	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001006777	homodimer interface [polypeptide binding]; other site
527001006778	catalytic residue [active]
527001006779	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
527001006780	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
527001006781	putative active site [active]
527001006782	metal binding site [ion binding]; metal-binding site
527001006783	Uncharacterized small protein [Function unknown]; Region: COG2879
527001006784	carbon starvation protein A; Provisional; Region: PRK15015
527001006785	Carbon starvation protein CstA; Region: CstA; pfam02554
527001006786	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
527001006787	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
527001006788	CoenzymeA binding site [chemical binding]; other site
527001006789	subunit interaction site [polypeptide binding]; other site
527001006790	PHB binding site; other site
527001006791	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
527001006792	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
527001006793	putative NAD(P) binding site [chemical binding]; other site
527001006794	active site
527001006795	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
527001006796	hydrophobic substrate binding pocket; other site
527001006797	Isochorismatase family; Region: Isochorismatase; pfam00857
527001006798	active site
527001006799	conserved cis-peptide bond; other site
527001006800	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
527001006801	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
527001006802	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
527001006803	acyl-activating enzyme (AAE) consensus motif; other site
527001006804	active site
527001006805	AMP binding site [chemical binding]; other site
527001006806	substrate binding site [chemical binding]; other site
527001006807	isochorismate synthase EntC; Provisional; Region: PRK15016
527001006808	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
527001006809	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
527001006810	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
527001006811	siderophore binding site; other site
527001006812	enterobactin exporter EntS; Provisional; Region: PRK10489
527001006813	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001006814	putative substrate translocation pore; other site
527001006815	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
527001006816	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
527001006817	ABC-ATPase subunit  interface; other site
527001006818	dimer interface [polypeptide binding]; other site
527001006819	putative PBP binding regions; other site
527001006820	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
527001006821	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
527001006822	ABC-ATPase subunit  interface; other site
527001006823	dimer interface [polypeptide binding]; other site
527001006824	putative PBP binding regions; other site
527001006825	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
527001006826	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
527001006827	Walker A/P-loop; other site
527001006828	ATP binding site [chemical binding]; other site
527001006829	Q-loop/lid; other site
527001006830	ABC transporter signature motif; other site
527001006831	Walker B; other site
527001006832	D-loop; other site
527001006833	H-loop/switch region; other site
527001006834	LPS O-antigen length regulator; Provisional; Region: PRK10381
527001006835	Chain length determinant protein; Region: Wzz; pfam02706
527001006836	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
527001006837	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
527001006838	acyl-activating enzyme (AAE) consensus motif; other site
527001006839	AMP binding site [chemical binding]; other site
527001006840	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
527001006841	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
527001006842	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
527001006843	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
527001006844	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
527001006845	outer membrane receptor FepA; Provisional; Region: PRK13524
527001006846	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
527001006847	N-terminal plug; other site
527001006848	ligand-binding site [chemical binding]; other site
527001006849	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
527001006850	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
527001006851	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
527001006852	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
527001006853	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
527001006854	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
527001006855	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001006856	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
527001006857	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001006858	hypothetical protein; Provisional; Region: PRK10250
527001006859	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
527001006860	dimer interface [polypeptide binding]; other site
527001006861	FMN binding site [chemical binding]; other site
527001006862	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
527001006863	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
527001006864	active site
527001006865	catalytic triad [active]
527001006866	oxyanion hole [active]
527001006867	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
527001006868	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
527001006869	Mechanosensitive ion channel; Region: MS_channel; pfam00924
527001006870	phenylalanine transporter; Provisional; Region: PRK10249
527001006871	Spore germination protein; Region: Spore_permease; cl17796
527001006872	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
527001006873	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
527001006874	HSP70 interaction site [polypeptide binding]; other site
527001006875	Predicted membrane protein [Function unknown]; Region: COG3059
527001006876	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
527001006877	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
527001006878	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001006879	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
527001006880	Cupin; Region: Cupin_6; pfam12852
527001006881	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
527001006882	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001006883	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
527001006884	Predicted membrane protein [Function unknown]; Region: COG2246
527001006885	GtrA-like protein; Region: GtrA; pfam04138
527001006886	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
527001006887	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
527001006888	Ligand binding site; other site
527001006889	Putative Catalytic site; other site
527001006890	DXD motif; other site
527001006891	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
527001006892	Transposase; Region: HTH_Tnp_1; pfam01527
527001006893	potential protein location (hypothetical protein TY21A_11705 [Salmonella enterica subsp. enterica serovar Typhi str. Ty21]) that overlaps RNA (tRNA-R)
527001006894	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
527001006895	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001006896	DNA binding residues [nucleotide binding]
527001006897	dimerization interface [polypeptide binding]; other site
527001006898	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
527001006899	transcriptional regulator FimZ; Provisional; Region: PRK09935
527001006900	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001006901	active site
527001006902	phosphorylation site [posttranslational modification]
527001006903	intermolecular recognition site; other site
527001006904	dimerization interface [polypeptide binding]; other site
527001006905	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001006906	DNA binding residues [nucleotide binding]
527001006907	dimerization interface [polypeptide binding]; other site
527001006908	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
527001006909	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
527001006910	outer membrane usher protein FimD; Provisional; Region: PRK15198
527001006911	PapC N-terminal domain; Region: PapC_N; pfam13954
527001006912	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
527001006913	PapC C-terminal domain; Region: PapC_C; pfam13953
527001006914	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
527001006915	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001006916	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001006917	fimbrial protein FimI; Provisional; Region: PRK15200
527001006918	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
527001006919	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
527001006920	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
527001006921	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
527001006922	homodimer interface [polypeptide binding]; other site
527001006923	NADP binding site [chemical binding]; other site
527001006924	substrate binding site [chemical binding]; other site
527001006925	ribosome-associated protein; Provisional; Region: PRK11507
527001006926	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
527001006927	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
527001006928	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
527001006929	active site
527001006930	HIGH motif; other site
527001006931	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
527001006932	KMSKS motif; other site
527001006933	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
527001006934	tRNA binding surface [nucleotide binding]; other site
527001006935	anticodon binding site; other site
527001006936	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
527001006937	substrate binding site [chemical binding]; other site
527001006938	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
527001006939	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
527001006940	putative active site [active]
527001006941	putative metal binding site [ion binding]; other site
527001006942	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
527001006943	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
527001006944	ATP-grasp domain; Region: ATP-grasp; pfam02222
527001006945	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
527001006946	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
527001006947	putative substrate binding site [chemical binding]; other site
527001006948	nucleotide binding site [chemical binding]; other site
527001006949	nucleotide binding site [chemical binding]; other site
527001006950	homodimer interface [polypeptide binding]; other site
527001006951	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
527001006952	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
527001006953	membrane protein FdrA; Validated; Region: PRK06091
527001006954	CoA binding domain; Region: CoA_binding; pfam02629
527001006955	CoA-ligase; Region: Ligase_CoA; pfam00549
527001006956	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
527001006957	allantoate amidohydrolase; Region: AllC; TIGR03176
527001006958	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
527001006959	active site
527001006960	metal binding site [ion binding]; metal-binding site
527001006961	dimer interface [polypeptide binding]; other site
527001006962	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
527001006963	Mif2/CENP-C like; Region: Mif2; pfam11699
527001006964	Cupin domain; Region: Cupin_2; pfam07883
527001006965	glycerate kinase II; Provisional; Region: PRK09932
527001006966	putative uracil/xanthine transporter; Provisional; Region: PRK11412
527001006967	allantoinase; Provisional; Region: PRK08044
527001006968	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
527001006969	active site
527001006970	potential frameshift: common BLAST hit: gi|224582359|ref|YP_002636157.1| allantoin permease
527001006971	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001006972	Major Facilitator Superfamily; Region: MFS_1; pfam07690
527001006973	putative substrate translocation pore; other site
527001006974	tartronate semialdehyde reductase; Provisional; Region: PRK15059
527001006975	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
527001006976	hydroxypyruvate isomerase; Provisional; Region: PRK09997
527001006977	glyoxylate carboligase; Provisional; Region: PRK11269
527001006978	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
527001006979	PYR/PP interface [polypeptide binding]; other site
527001006980	dimer interface [polypeptide binding]; other site
527001006981	TPP binding site [chemical binding]; other site
527001006982	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
527001006983	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
527001006984	TPP-binding site [chemical binding]; other site
527001006985	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
527001006986	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
527001006987	Bacterial transcriptional regulator; Region: IclR; pfam01614
527001006988	potential frameshift: common BLAST hit: gi|197251807|ref|YP_002145499.1| ureidoglycolate hydrolase
527001006989	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
527001006990	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001006991	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
527001006992	dimerization interface [polypeptide binding]; other site
527001006993	Predicted ATPase [General function prediction only]; Region: COG2603
527001006994	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
527001006995	active site residue [active]
527001006996	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001006997	dimer interface [polypeptide binding]; other site
527001006998	conserved gate region; other site
527001006999	ABC-ATPase subunit interface; other site
527001007000	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
527001007001	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
527001007002	Walker A/P-loop; other site
527001007003	ATP binding site [chemical binding]; other site
527001007004	Q-loop/lid; other site
527001007005	ABC transporter signature motif; other site
527001007006	Walker B; other site
527001007007	D-loop; other site
527001007008	H-loop/switch region; other site
527001007009	NIL domain; Region: NIL; pfam09383
527001007010	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
527001007011	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
527001007012	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
527001007013	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
527001007014	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
527001007015	FtsX-like permease family; Region: FtsX; pfam02687
527001007016	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
527001007017	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
527001007018	Walker A/P-loop; other site
527001007019	ATP binding site [chemical binding]; other site
527001007020	Q-loop/lid; other site
527001007021	ABC transporter signature motif; other site
527001007022	Walker B; other site
527001007023	D-loop; other site
527001007024	H-loop/switch region; other site
527001007025	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
527001007026	active site
527001007027	catalytic triad [active]
527001007028	oxyanion hole [active]
527001007029	switch loop; other site
527001007030	oxidoreductase; Provisional; Region: PRK08017
527001007031	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
527001007032	NADP binding site [chemical binding]; other site
527001007033	active site
527001007034	steroid binding site; other site
527001007035	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
527001007036	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
527001007037	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
527001007038	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
527001007039	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
527001007040	Walker A/P-loop; other site
527001007041	ATP binding site [chemical binding]; other site
527001007042	Q-loop/lid; other site
527001007043	ABC transporter signature motif; other site
527001007044	Walker B; other site
527001007045	D-loop; other site
527001007046	H-loop/switch region; other site
527001007047	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
527001007048	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
527001007049	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
527001007050	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
527001007051	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
527001007052	DNA binding residues [nucleotide binding]
527001007053	dimer interface [polypeptide binding]; other site
527001007054	copper binding site [ion binding]; other site
527001007055	copper exporting ATPase; Provisional; Region: copA; PRK10671
527001007056	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
527001007057	metal-binding site [ion binding]
527001007058	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
527001007059	metal-binding site [ion binding]
527001007060	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
527001007061	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001007062	motif II; other site
527001007063	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
527001007064	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
527001007065	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
527001007066	putative deacylase active site [active]
527001007067	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
527001007068	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
527001007069	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
527001007070	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
527001007071	active site
527001007072	metal binding site [ion binding]; metal-binding site
527001007073	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001007074	Major Facilitator Superfamily; Region: MFS_1; pfam07690
527001007075	putative substrate translocation pore; other site
527001007076	putative cation:proton antiport protein; Provisional; Region: PRK10669
527001007077	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
527001007078	TrkA-N domain; Region: TrkA_N; pfam02254
527001007079	inosine/guanosine kinase; Provisional; Region: PRK15074
527001007080	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
527001007081	acetyl esterase; Provisional; Region: PRK10162
527001007082	ferrochelatase; Reviewed; Region: hemH; PRK00035
527001007083	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
527001007084	C-terminal domain interface [polypeptide binding]; other site
527001007085	active site
527001007086	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
527001007087	active site
527001007088	N-terminal domain interface [polypeptide binding]; other site
527001007089	adenylate kinase; Reviewed; Region: adk; PRK00279
527001007090	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
527001007091	AMP-binding site [chemical binding]; other site
527001007092	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
527001007093	heat shock protein 90; Provisional; Region: PRK05218
527001007094	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001007095	ATP binding site [chemical binding]; other site
527001007096	Mg2+ binding site [ion binding]; other site
527001007097	G-X-G motif; other site
527001007098	recombination protein RecR; Reviewed; Region: recR; PRK00076
527001007099	RecR protein; Region: RecR; pfam02132
527001007100	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
527001007101	putative active site [active]
527001007102	putative metal-binding site [ion binding]; other site
527001007103	tetramer interface [polypeptide binding]; other site
527001007104	hypothetical protein; Validated; Region: PRK00153
527001007105	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
527001007106	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001007107	Walker A motif; other site
527001007108	ATP binding site [chemical binding]; other site
527001007109	Walker B motif; other site
527001007110	DNA polymerase III subunit delta'; Validated; Region: PRK08485
527001007111	arginine finger; other site
527001007112	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
527001007113	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
527001007114	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
527001007115	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
527001007116	active site
527001007117	hypothetical protein; Provisional; Region: PRK10527
527001007118	Primosomal replication protein priB and priC; Region: priB_priC; cl11483
527001007119	hypothetical protein; Provisional; Region: PRK11038
527001007120	Uncharacterized conserved protein [Function unknown]; Region: COG5464
527001007121	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
527001007122	hypothetical protein; Provisional; Region: PRK11281
527001007123	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
527001007124	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
527001007125	Mechanosensitive ion channel; Region: MS_channel; pfam00924
527001007126	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
527001007127	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001007128	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
527001007129	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
527001007130	HlyD family secretion protein; Region: HlyD_3; pfam13437
527001007131	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
527001007132	Protein export membrane protein; Region: SecD_SecF; cl14618
527001007133	Protein export membrane protein; Region: SecD_SecF; cl14618
527001007134	Hha toxicity attenuator; Provisional; Region: PRK10667
527001007135	gene expression modulator; Provisional; Region: PRK10945
527001007136	maltose O-acetyltransferase; Provisional; Region: PRK10092
527001007137	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
527001007138	active site
527001007139	substrate binding site [chemical binding]; other site
527001007140	trimer interface [polypeptide binding]; other site
527001007141	CoA binding site [chemical binding]; other site
527001007142	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
527001007143	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
527001007144	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
527001007145	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
527001007146	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
527001007147	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001007148	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
527001007149	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
527001007150	DNA binding site [nucleotide binding]
527001007151	active site
527001007152	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
527001007153	acyl-CoA thioesterase II; Provisional; Region: PRK10526
527001007154	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
527001007155	active site
527001007156	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
527001007157	catalytic triad [active]
527001007158	dimer interface [polypeptide binding]; other site
527001007159	ammonium transporter; Provisional; Region: PRK10666
527001007160	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
527001007161	Nitrogen regulatory protein P-II; Region: P-II; smart00938
527001007162	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
527001007163	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
527001007164	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001007165	Walker A/P-loop; other site
527001007166	ATP binding site [chemical binding]; other site
527001007167	Q-loop/lid; other site
527001007168	ABC transporter signature motif; other site
527001007169	Walker B; other site
527001007170	D-loop; other site
527001007171	H-loop/switch region; other site
527001007172	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
527001007173	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
527001007174	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001007175	Walker A/P-loop; other site
527001007176	ATP binding site [chemical binding]; other site
527001007177	Q-loop/lid; other site
527001007178	ABC transporter signature motif; other site
527001007179	Walker B; other site
527001007180	D-loop; other site
527001007181	H-loop/switch region; other site
527001007182	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
527001007183	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
527001007184	putative DNA binding site [nucleotide binding]; other site
527001007185	putative Zn2+ binding site [ion binding]; other site
527001007186	AsnC family; Region: AsnC_trans_reg; pfam01037
527001007187	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
527001007188	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
527001007189	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
527001007190	catalytic residue [active]
527001007191	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001007192	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
527001007193	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001007194	active site
527001007195	motif I; other site
527001007196	motif II; other site
527001007197	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
527001007198	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
527001007199	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
527001007200	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
527001007201	Ligand Binding Site [chemical binding]; other site
527001007202	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
527001007203	active site
527001007204	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
527001007205	periplasmic folding chaperone; Provisional; Region: PRK10788
527001007206	SurA N-terminal domain; Region: SurA_N_3; cl07813
527001007207	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
527001007208	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
527001007209	IHF dimer interface [polypeptide binding]; other site
527001007210	IHF - DNA interface [nucleotide binding]; other site
527001007211	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
527001007212	Found in ATP-dependent protease La (LON); Region: LON; smart00464
527001007213	Found in ATP-dependent protease La (LON); Region: LON; smart00464
527001007214	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001007215	Walker A motif; other site
527001007216	ATP binding site [chemical binding]; other site
527001007217	Walker B motif; other site
527001007218	arginine finger; other site
527001007219	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
527001007220	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
527001007221	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
527001007222	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001007223	Walker A motif; other site
527001007224	ATP binding site [chemical binding]; other site
527001007225	Walker B motif; other site
527001007226	Iron permease FTR1 family; Region: FTR1; cl00475
527001007227	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
527001007228	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
527001007229	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
527001007230	oligomer interface [polypeptide binding]; other site
527001007231	active site residues [active]
527001007232	trigger factor; Provisional; Region: tig; PRK01490
527001007233	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
527001007234	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
527001007235	transcriptional regulator BolA; Provisional; Region: PRK11628
527001007236	hypothetical protein; Provisional; Region: PRK11627
527001007237	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
527001007238	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
527001007239	muropeptide transporter; Reviewed; Region: ampG; PRK11902
527001007240	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001007241	putative substrate translocation pore; other site
527001007242	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
527001007243	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
527001007244	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
527001007245	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
527001007246	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
527001007247	D-pathway; other site
527001007248	Putative ubiquinol binding site [chemical binding]; other site
527001007249	Low-spin heme (heme b) binding site [chemical binding]; other site
527001007250	Putative water exit pathway; other site
527001007251	Binuclear center (heme o3/CuB) [ion binding]; other site
527001007252	K-pathway; other site
527001007253	Putative proton exit pathway; other site
527001007254	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
527001007255	Subunit III/IV interface [polypeptide binding]; other site
527001007256	Subunit I/III interface [polypeptide binding]; other site
527001007257	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
527001007258	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
527001007259	UbiA prenyltransferase family; Region: UbiA; pfam01040
527001007260	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
527001007261	Sel1-like repeats; Region: SEL1; smart00671
527001007262	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
527001007263	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
527001007264	Sel1-like repeats; Region: SEL1; smart00671
527001007265	potential frameshift: common BLAST hit: gi|224582275|ref|YP_002636073.1| putative periplasmic protein
527001007266	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001007267	Major Facilitator Superfamily; Region: MFS_1; pfam07690
527001007268	putative substrate translocation pore; other site
527001007269	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
527001007270	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
527001007271	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
527001007272	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
527001007273	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
527001007274	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
527001007275	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
527001007276	conserved cys residue [active]
527001007277	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
527001007278	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001007279	motif II; other site
527001007280	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
527001007281	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
527001007282	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
527001007283	catalytic residue [active]
527001007284	transcriptional regulator protein; Region: phnR; TIGR03337
527001007285	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001007286	DNA-binding site [nucleotide binding]; DNA binding site
527001007287	UTRA domain; Region: UTRA; pfam07702
527001007288	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
527001007289	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
527001007290	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
527001007291	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001007292	Walker A/P-loop; other site
527001007293	ATP binding site [chemical binding]; other site
527001007294	Q-loop/lid; other site
527001007295	ABC transporter signature motif; other site
527001007296	Walker B; other site
527001007297	D-loop; other site
527001007298	H-loop/switch region; other site
527001007299	TOBE domain; Region: TOBE_2; pfam08402
527001007300	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
527001007301	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001007302	dimer interface [polypeptide binding]; other site
527001007303	conserved gate region; other site
527001007304	putative PBP binding loops; other site
527001007305	ABC-ATPase subunit interface; other site
527001007306	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
527001007307	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001007308	dimer interface [polypeptide binding]; other site
527001007309	conserved gate region; other site
527001007310	putative PBP binding loops; other site
527001007311	ABC-ATPase subunit interface; other site
527001007312	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
527001007313	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
527001007314	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
527001007315	Ligand Binding Site [chemical binding]; other site
527001007316	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
527001007317	active site residue [active]
527001007318	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
527001007319	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
527001007320	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
527001007321	substrate binding pocket [chemical binding]; other site
527001007322	chain length determination region; other site
527001007323	substrate-Mg2+ binding site; other site
527001007324	catalytic residues [active]
527001007325	aspartate-rich region 1; other site
527001007326	active site lid residues [active]
527001007327	aspartate-rich region 2; other site
527001007328	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
527001007329	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
527001007330	TPP-binding site; other site
527001007331	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
527001007332	PYR/PP interface [polypeptide binding]; other site
527001007333	dimer interface [polypeptide binding]; other site
527001007334	TPP binding site [chemical binding]; other site
527001007335	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
527001007336	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
527001007337	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
527001007338	active site
527001007339	catalytic tetrad [active]
527001007340	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
527001007341	tetramer interfaces [polypeptide binding]; other site
527001007342	binuclear metal-binding site [ion binding]; other site
527001007343	thiamine monophosphate kinase; Provisional; Region: PRK05731
527001007344	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
527001007345	ATP binding site [chemical binding]; other site
527001007346	dimerization interface [polypeptide binding]; other site
527001007347	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
527001007348	putative RNA binding site [nucleotide binding]; other site
527001007349	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
527001007350	homopentamer interface [polypeptide binding]; other site
527001007351	active site
527001007352	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
527001007353	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
527001007354	catalytic motif [active]
527001007355	Zn binding site [ion binding]; other site
527001007356	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
527001007357	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
527001007358	ATP cone domain; Region: ATP-cone; pfam03477
527001007359	hypothetical protein; Provisional; Region: PRK11530
527001007360	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
527001007361	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
527001007362	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
527001007363	active site
527001007364	Predicted transcriptional regulator [Transcription]; Region: COG2378
527001007365	HTH domain; Region: HTH_11; pfam08279
527001007366	WYL domain; Region: WYL; pfam13280
527001007367	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
527001007368	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
527001007369	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
527001007370	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
527001007371	Protein export membrane protein; Region: SecD_SecF; pfam02355
527001007372	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
527001007373	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
527001007374	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
527001007375	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
527001007376	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
527001007377	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
527001007378	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
527001007379	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
527001007380	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
527001007381	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
527001007382	peroxidase; Provisional; Region: PRK15000
527001007383	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
527001007384	dimer interface [polypeptide binding]; other site
527001007385	decamer (pentamer of dimers) interface [polypeptide binding]; other site
527001007386	catalytic triad [active]
527001007387	peroxidatic and resolving cysteines [active]
527001007388	maltodextrin glucosidase; Provisional; Region: PRK10785
527001007389	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
527001007390	homodimer interface [polypeptide binding]; other site
527001007391	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
527001007392	active site
527001007393	homodimer interface [polypeptide binding]; other site
527001007394	catalytic site [active]
527001007395	putative proline-specific permease; Provisional; Region: proY; PRK10580
527001007396	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001007397	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
527001007398	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
527001007399	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
527001007400	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
527001007401	putative active site [active]
527001007402	heme pocket [chemical binding]; other site
527001007403	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001007404	dimer interface [polypeptide binding]; other site
527001007405	phosphorylation site [posttranslational modification]
527001007406	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001007407	ATP binding site [chemical binding]; other site
527001007408	Mg2+ binding site [ion binding]; other site
527001007409	G-X-G motif; other site
527001007410	transcriptional regulator PhoB; Provisional; Region: PRK10161
527001007411	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001007412	active site
527001007413	phosphorylation site [posttranslational modification]
527001007414	intermolecular recognition site; other site
527001007415	dimerization interface [polypeptide binding]; other site
527001007416	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001007417	DNA binding site [nucleotide binding]
527001007418	exonuclease subunit SbcD; Provisional; Region: PRK10966
527001007419	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
527001007420	active site
527001007421	metal binding site [ion binding]; metal-binding site
527001007422	DNA binding site [nucleotide binding]
527001007423	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
527001007424	exonuclease subunit SbcC; Provisional; Region: PRK10246
527001007425	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001007426	Walker A/P-loop; other site
527001007427	ATP binding site [chemical binding]; other site
527001007428	Q-loop/lid; other site
527001007429	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001007430	ABC transporter signature motif; other site
527001007431	Walker B; other site
527001007432	D-loop; other site
527001007433	H-loop/switch region; other site
527001007434	potential frameshift: common BLAST hit: gi|207855876|ref|YP_002242527.1| MFS transport protein AraJ
527001007435	fructokinase; Reviewed; Region: PRK09557
527001007436	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
527001007437	nucleotide binding site [chemical binding]; other site
527001007438	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
527001007439	hypothetical protein; Provisional; Region: PRK10579
527001007440	AroM protein; Region: AroM; cl17601
527001007441	hypothetical protein; Provisional; Region: PRK10380
527001007442	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
527001007443	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
527001007444	ADP binding site [chemical binding]; other site
527001007445	magnesium binding site [ion binding]; other site
527001007446	putative shikimate binding site; other site
527001007447	hypothetical protein; Validated; Region: PRK00124
527001007448	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
527001007449	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
527001007450	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
527001007451	MASE2 domain; Region: MASE2; pfam05230
527001007452	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001007453	metal binding site [ion binding]; metal-binding site
527001007454	active site
527001007455	I-site; other site
527001007456	hypothetical protein; Provisional; Region: PRK11505
527001007457	psiF repeat; Region: PsiF_repeat; pfam07769
527001007458	psiF repeat; Region: PsiF_repeat; pfam07769
527001007459	anti-RssB factor; Provisional; Region: PRK10244
527001007460	drug efflux system protein MdtG; Provisional; Region: PRK09874
527001007461	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001007462	putative substrate translocation pore; other site
527001007463	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
527001007464	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
527001007465	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
527001007466	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
527001007467	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
527001007468	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
527001007469	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
527001007470	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
527001007471	microcin B17 transporter; Reviewed; Region: PRK11098
527001007472	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
527001007473	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
527001007474	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
527001007475	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
527001007476	ligand binding site [chemical binding]; other site
527001007477	flexible hinge region; other site
527001007478	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
527001007479	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
527001007480	Autotransporter beta-domain; Region: Autotransporter; pfam03797
527001007481	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
527001007482	dimer interface [polypeptide binding]; other site
527001007483	active site
527001007484	Schiff base residues; other site
527001007485	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
527001007486	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
527001007487	acyl-activating enzyme (AAE) consensus motif; other site
527001007488	AMP binding site [chemical binding]; other site
527001007489	active site
527001007490	CoA binding site [chemical binding]; other site
527001007491	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
527001007492	2-methylcitrate dehydratase; Region: prpD; TIGR02330
527001007493	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
527001007494	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
527001007495	dimer interface [polypeptide binding]; other site
527001007496	active site
527001007497	citrylCoA binding site [chemical binding]; other site
527001007498	oxalacetate/citrate binding site [chemical binding]; other site
527001007499	coenzyme A binding site [chemical binding]; other site
527001007500	catalytic triad [active]
527001007501	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
527001007502	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
527001007503	tetramer interface [polypeptide binding]; other site
527001007504	active site
527001007505	Mg2+/Mn2+ binding site [ion binding]; other site
527001007506	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
527001007507	Propionate catabolism activator; Region: PrpR_N; pfam06506
527001007508	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001007509	Walker A motif; other site
527001007510	ATP binding site [chemical binding]; other site
527001007511	Walker B motif; other site
527001007512	arginine finger; other site
527001007513	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
527001007514	hypothetical protein; Provisional; Region: PRK09929
527001007515	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
527001007516	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
527001007517	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
527001007518	N-terminal plug; other site
527001007519	ligand-binding site [chemical binding]; other site
527001007520	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
527001007521	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
527001007522	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
527001007523	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
527001007524	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
527001007525	potential frameshift: common BLAST hit: gi|194442308|ref|YP_002039596.1| type III restriction-modification system StyLTI enzyme res
527001007526	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
527001007527	DNA methylase; Region: N6_N4_Mtase; cl17433
527001007528	DNA methylase; Region: N6_N4_Mtase; pfam01555
527001007529	putative sialic acid transporter; Region: 2A0112; TIGR00891
527001007530	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001007531	putative substrate translocation pore; other site
527001007532	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
527001007533	metal-binding site [ion binding]
527001007534	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
527001007535	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
527001007536	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
527001007537	DNA binding residues [nucleotide binding]
527001007538	dimerization interface [polypeptide binding]; other site
527001007539	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
527001007540	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
527001007541	DNA binding site [nucleotide binding]
527001007542	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
527001007543	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001007544	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
527001007545	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
527001007546	fimbrial chaperone protein StbB; Provisional; Region: PRK15249
527001007547	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001007548	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001007549	potential frameshift: common BLAST hit: gi|16759321|ref|NP_454938.1| outer membrane fimbrial usher protein
527001007550	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
527001007551	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
527001007552	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001007553	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001007554	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
527001007555	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
527001007556	putative catalytic cysteine [active]
527001007557	gamma-glutamyl kinase; Provisional; Region: PRK05429
527001007558	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
527001007559	nucleotide binding site [chemical binding]; other site
527001007560	homotetrameric interface [polypeptide binding]; other site
527001007561	putative phosphate binding site [ion binding]; other site
527001007562	putative allosteric binding site; other site
527001007563	PUA domain; Region: PUA; pfam01472
527001007564	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
527001007565	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
527001007566	trimer interface [polypeptide binding]; other site
527001007567	eyelet of channel; other site
527001007568	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
527001007569	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
527001007570	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
527001007571	active site
527001007572	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
527001007573	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
527001007574	metal binding site [ion binding]; metal-binding site
527001007575	dimer interface [polypeptide binding]; other site
527001007576	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
527001007577	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
527001007578	hypothetical protein; Reviewed; Region: PRK09588
527001007579	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
527001007580	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
527001007581	active site
527001007582	DNA polymerase IV; Validated; Region: PRK02406
527001007583	DNA binding site [nucleotide binding]
527001007584	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
527001007585	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
527001007586	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
527001007587	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
527001007588	putative active site [active]
527001007589	putative dimer interface [polypeptide binding]; other site
527001007590	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
527001007591	dimer interface [polypeptide binding]; other site
527001007592	active site
527001007593	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
527001007594	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
527001007595	active site
527001007596	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
527001007597	C-N hydrolase family amidase; Provisional; Region: PRK10438
527001007598	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
527001007599	putative active site [active]
527001007600	catalytic triad [active]
527001007601	dimer interface [polypeptide binding]; other site
527001007602	multimer interface [polypeptide binding]; other site
527001007603	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
527001007604	dimer interface [polypeptide binding]; other site
527001007605	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
527001007606	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
527001007607	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
527001007608	AsnC family; Region: AsnC_trans_reg; pfam01037
527001007609	putative fimbrial protein TcfD; Provisional; Region: PRK15311
527001007610	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
527001007611	putative fimbrial subunit TcfB; Provisional; Region: PRK15309
527001007612	putative fimbrial protein TcfA; Provisional; Region: PRK15308
527001007613	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
527001007614	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
527001007615	Transposase; Region: HTH_Tnp_1; cl17663
527001007616	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001007617	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001007618	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
527001007619	dimerization interface [polypeptide binding]; other site
527001007620	PerC transcriptional activator; Region: PerC; pfam06069
527001007621	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
527001007622	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
527001007623	putative active site [active]
527001007624	putative metal binding site [ion binding]; other site
527001007625	putative pilin structural protein SafD; Provisional; Region: PRK15222
527001007626	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
527001007627	PapC N-terminal domain; Region: PapC_N; pfam13954
527001007628	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
527001007629	PapC C-terminal domain; Region: PapC_C; pfam13953
527001007630	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
527001007631	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001007632	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001007633	Saf-pilin pilus formation protein; Region: Saf-Nte_pilin; cl09697
527001007634	Saf-pilin pilus formation protein SafA; Provisional; Region: PRK15221
527001007635	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
527001007636	Integrase core domain; Region: rve_3; pfam13683
527001007637	Transposase; Region: HTH_Tnp_1; cl17663
527001007638	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
527001007639	RHS Repeat; Region: RHS_repeat; cl11982
527001007640	RHS Repeat; Region: RHS_repeat; pfam05593
527001007641	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
527001007642	RHS Repeat; Region: RHS_repeat; pfam05593
527001007643	RHS Repeat; Region: RHS_repeat; pfam05593
527001007644	RHS Repeat; Region: RHS_repeat; pfam05593
527001007645	RHS Repeat; Region: RHS_repeat; pfam05593
527001007646	RHS protein; Region: RHS; pfam03527
527001007647	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
527001007648	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
527001007649	PAAR motif; Region: PAAR_motif; pfam05488
527001007650	RHS Repeat; Region: RHS_repeat; cl11982
527001007651	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
527001007652	RHS Repeat; Region: RHS_repeat; pfam05593
527001007653	RHS Repeat; Region: RHS_repeat; pfam05593
527001007654	RHS protein; Region: RHS; pfam03527
527001007655	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
527001007656	A nuclease family of the HNH/ENDO VII superfamily with conserved AHH; Region: AHH; pfam14412
527001007657	Uncharacterized conserved protein [Function unknown]; Region: COG5435
527001007658	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501
527001007659	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
527001007660	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
527001007661	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4893
527001007662	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
527001007663	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; cl01611
527001007664	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
527001007665	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
527001007666	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
527001007667	Protein of unknown function (DUF3036); Region: DUF3036; pfam11234
527001007668	ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331
527001007669	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
527001007670	hypothetical protein; Provisional; Region: PRK08126
527001007671	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
527001007672	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
527001007673	ligand binding site [chemical binding]; other site
527001007674	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
527001007675	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
527001007676	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
527001007677	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
527001007678	potential frameshift: common BLAST hit: gi|194736373|ref|YP_002113292.1| type VI secretion protein, EvpB/family
527001007679	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
527001007680	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
527001007681	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001007682	Walker A motif; other site
527001007683	ATP binding site [chemical binding]; other site
527001007684	Walker B motif; other site
527001007685	arginine finger; other site
527001007686	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001007687	Walker A motif; other site
527001007688	ATP binding site [chemical binding]; other site
527001007689	Walker B motif; other site
527001007690	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
527001007691	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
527001007692	ImpE protein; Region: ImpE; pfam07024
527001007693	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
527001007694	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
527001007695	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
527001007696	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
527001007697	potential frameshift: common BLAST hit: gi|198245787|ref|YP_002214221.1| ImpA-related protein
527001007698	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
527001007699	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
527001007700	active site
527001007701	catalytic site [active]
527001007702	substrate binding site [chemical binding]; other site
527001007703	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
527001007704	RNA/DNA hybrid binding site [nucleotide binding]; other site
527001007705	active site
527001007706	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001007707	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
527001007708	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
527001007709	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
527001007710	N-acetyl-D-glucosamine binding site [chemical binding]; other site
527001007711	catalytic residue [active]
527001007712	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
527001007713	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
527001007714	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
527001007715	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
527001007716	Methyltransferase domain; Region: Methyltransf_23; pfam13489
527001007717	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001007718	S-adenosylmethionine binding site [chemical binding]; other site
527001007719	hypothetical protein; Provisional; Region: PRK05421
527001007720	putative catalytic site [active]
527001007721	putative metal binding site [ion binding]; other site
527001007722	putative phosphate binding site [ion binding]; other site
527001007723	putative catalytic site [active]
527001007724	putative phosphate binding site [ion binding]; other site
527001007725	putative metal binding site [ion binding]; other site
527001007726	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
527001007727	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001007728	putative substrate translocation pore; other site
527001007729	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001007730	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001007731	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
527001007732	putative effector binding pocket; other site
527001007733	dimerization interface [polypeptide binding]; other site
527001007734	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
527001007735	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
527001007736	active site
527001007737	catalytic tetrad [active]
527001007738	protein disaggregation chaperone; Provisional; Region: PRK10865
527001007739	Clp amino terminal domain; Region: Clp_N; pfam02861
527001007740	Clp amino terminal domain; Region: Clp_N; pfam02861
527001007741	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001007742	Walker A motif; other site
527001007743	ATP binding site [chemical binding]; other site
527001007744	Walker B motif; other site
527001007745	arginine finger; other site
527001007746	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001007747	Walker A motif; other site
527001007748	ATP binding site [chemical binding]; other site
527001007749	Walker B motif; other site
527001007750	arginine finger; other site
527001007751	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
527001007752	hypothetical protein; Provisional; Region: PRK10723
527001007753	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
527001007754	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
527001007755	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
527001007756	RNA binding surface [nucleotide binding]; other site
527001007757	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
527001007758	active site
527001007759	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
527001007760	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
527001007761	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
527001007762	30S subunit binding site; other site
527001007763	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
527001007764	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
527001007765	Prephenate dehydratase; Region: PDT; pfam00800
527001007766	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
527001007767	putative L-Phe binding site [chemical binding]; other site
527001007768	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
527001007769	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
527001007770	Chorismate mutase type II; Region: CM_2; cl00693
527001007771	prephenate dehydrogenase; Validated; Region: PRK08507
527001007772	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
527001007773	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
527001007774	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
527001007775	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
527001007776	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001007777	metal binding site [ion binding]; metal-binding site
527001007778	active site
527001007779	I-site; other site
527001007780	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
527001007781	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
527001007782	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
527001007783	RimM N-terminal domain; Region: RimM; pfam01782
527001007784	PRC-barrel domain; Region: PRC; pfam05239
527001007785	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
527001007786	signal recognition particle protein; Provisional; Region: PRK10867
527001007787	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
527001007788	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
527001007789	P loop; other site
527001007790	GTP binding site [chemical binding]; other site
527001007791	Signal peptide binding domain; Region: SRP_SPB; pfam02978
527001007792	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
527001007793	hypothetical protein; Provisional; Region: PRK11573
527001007794	Domain of unknown function DUF21; Region: DUF21; pfam01595
527001007795	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
527001007796	Transporter associated domain; Region: CorC_HlyC; smart01091
527001007797	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
527001007798	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
527001007799	dimer interface [polypeptide binding]; other site
527001007800	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
527001007801	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
527001007802	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
527001007803	recombination and repair protein; Provisional; Region: PRK10869
527001007804	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
527001007805	Walker A/P-loop; other site
527001007806	ATP binding site [chemical binding]; other site
527001007807	Q-loop/lid; other site
527001007808	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
527001007809	ABC transporter signature motif; other site
527001007810	Walker B; other site
527001007811	D-loop; other site
527001007812	H-loop/switch region; other site
527001007813	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
527001007814	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
527001007815	hypothetical protein; Validated; Region: PRK01777
527001007816	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
527001007817	putative coenzyme Q binding site [chemical binding]; other site
527001007818	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
527001007819	SmpB-tmRNA interface; other site
527001007820	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001007821	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001007822	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001007823	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001007824	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001007825	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001007826	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
527001007827	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001007828	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001007829	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
527001007830	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001007831	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001007832	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
527001007833	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
527001007834	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
527001007835	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
527001007836	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001007837	Walker A/P-loop; other site
527001007838	ATP binding site [chemical binding]; other site
527001007839	Q-loop/lid; other site
527001007840	ABC transporter signature motif; other site
527001007841	Walker B; other site
527001007842	D-loop; other site
527001007843	H-loop/switch region; other site
527001007844	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
527001007845	HlyD family secretion protein; Region: HlyD_3; pfam13437
527001007846	integrase; Provisional; Region: PRK09692
527001007847	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
527001007848	active site
527001007849	Int/Topo IB signature motif; other site
527001007850	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
527001007851	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
527001007852	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
527001007853	Ash protein family; Region: Phage_ASH; pfam10554
527001007854	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
527001007855	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
527001007856	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
527001007857	active site
527001007858	metal binding site [ion binding]; metal-binding site
527001007859	interdomain interaction site; other site
527001007860	D5 N terminal like; Region: D5_N; smart00885
527001007861	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
527001007862	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
527001007863	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
527001007864	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
527001007865	putative active site [active]
527001007866	putative NTP binding site [chemical binding]; other site
527001007867	putative nucleic acid binding site [nucleotide binding]; other site
527001007868	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
527001007869	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
527001007870	tail protein; Provisional; Region: D; PHA02561
527001007871	Phage protein U [General function prediction only]; Region: COG3499
527001007872	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
527001007873	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
527001007874	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
527001007875	major tail tube protein; Provisional; Region: FII; PHA02600
527001007876	major tail sheath protein; Provisional; Region: FI; PHA02560
527001007877	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
527001007878	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
527001007879	catalytic residues [active]
527001007880	catalytic nucleophile [active]
527001007881	Presynaptic Site I dimer interface [polypeptide binding]; other site
527001007882	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
527001007883	Synaptic Flat tetramer interface [polypeptide binding]; other site
527001007884	Synaptic Site I dimer interface [polypeptide binding]; other site
527001007885	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
527001007886	DNA-binding interface [nucleotide binding]; DNA binding site
527001007887	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
527001007888	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
527001007889	homodimer interface [polypeptide binding]; other site
527001007890	active site
527001007891	TDP-binding site; other site
527001007892	acceptor substrate-binding pocket; other site
527001007893	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
527001007894	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001007895	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
527001007896	Walker A/P-loop; other site
527001007897	ATP binding site [chemical binding]; other site
527001007898	Q-loop/lid; other site
527001007899	ABC transporter signature motif; other site
527001007900	Walker B; other site
527001007901	D-loop; other site
527001007902	H-loop/switch region; other site
527001007903	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
527001007904	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
527001007905	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001007906	Walker A/P-loop; other site
527001007907	ATP binding site [chemical binding]; other site
527001007908	Q-loop/lid; other site
527001007909	ABC transporter signature motif; other site
527001007910	Walker B; other site
527001007911	D-loop; other site
527001007912	H-loop/switch region; other site
527001007913	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
527001007914	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
527001007915	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
527001007916	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
527001007917	outer membrane receptor FepA; Provisional; Region: PRK13528
527001007918	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
527001007919	N-terminal plug; other site
527001007920	ligand-binding site [chemical binding]; other site
527001007921	secreted effector protein PipB2; Provisional; Region: PRK15196
527001007922	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
527001007923	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
527001007924	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
527001007925	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
527001007926	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
527001007927	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
527001007928	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
527001007929	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
527001007930	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
527001007931	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
527001007932	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
527001007933	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
527001007934	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001007935	dimer interface [polypeptide binding]; other site
527001007936	phosphorylation site [posttranslational modification]
527001007937	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001007938	ATP binding site [chemical binding]; other site
527001007939	Mg2+ binding site [ion binding]; other site
527001007940	G-X-G motif; other site
527001007941	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
527001007942	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001007943	active site
527001007944	phosphorylation site [posttranslational modification]
527001007945	intermolecular recognition site; other site
527001007946	dimerization interface [polypeptide binding]; other site
527001007947	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001007948	DNA binding site [nucleotide binding]
527001007949	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
527001007950	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
527001007951	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
527001007952	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
527001007953	substrate binding pocket [chemical binding]; other site
527001007954	active site
527001007955	iron coordination sites [ion binding]; other site
527001007956	Predicted dehydrogenase [General function prediction only]; Region: COG0579
527001007957	hydroxyglutarate oxidase; Provisional; Region: PRK11728
527001007958	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
527001007959	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
527001007960	tetramerization interface [polypeptide binding]; other site
527001007961	NAD(P) binding site [chemical binding]; other site
527001007962	catalytic residues [active]
527001007963	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
527001007964	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
527001007965	inhibitor-cofactor binding pocket; inhibition site
527001007966	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001007967	catalytic residue [active]
527001007968	potential frameshift: common BLAST hit: gi|16761575|ref|NP_457192.1| gamma-aminobutyrate transporter
527001007969	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
527001007970	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001007971	DNA-binding site [nucleotide binding]; DNA binding site
527001007972	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
527001007973	potential frameshift: common BLAST hit: gi|197363681|ref|YP_002143318.1| LysM domain/BON superfamily protein
527001007974	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
527001007975	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
527001007976	dimerization interface [polypeptide binding]; other site
527001007977	putative DNA binding site [nucleotide binding]; other site
527001007978	putative Zn2+ binding site [ion binding]; other site
527001007979	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
527001007980	active site residue [active]
527001007981	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
527001007982	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
527001007983	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
527001007984	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
527001007985	hypothetical protein; Provisional; Region: PRK10556
527001007986	hypothetical protein; Provisional; Region: PRK10132
527001007987	potential frameshift: common BLAST hit: gi|194447824|ref|YP_002046765.1| GntR family transcriptional regulator
527001007988	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
527001007989	Uncharacterized conserved protein [Function unknown]; Region: COG2128
527001007990	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
527001007991	catalytic residues [active]
527001007992	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
527001007993	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
527001007994	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
527001007995	Class I ribonucleotide reductase; Region: RNR_I; cd01679
527001007996	active site
527001007997	dimer interface [polypeptide binding]; other site
527001007998	catalytic residues [active]
527001007999	effector binding site; other site
527001008000	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
527001008001	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
527001008002	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
527001008003	dimer interface [polypeptide binding]; other site
527001008004	putative radical transfer pathway; other site
527001008005	diiron center [ion binding]; other site
527001008006	tyrosyl radical; other site
527001008007	potential frameshift: common BLAST hit: gi|197251048|ref|YP_002147709.1| glycine betaine transporter ATP-binding subunit
527001008008	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
527001008009	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001008010	dimer interface [polypeptide binding]; other site
527001008011	conserved gate region; other site
527001008012	putative PBP binding loops; other site
527001008013	ABC-ATPase subunit interface; other site
527001008014	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
527001008015	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
527001008016	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
527001008017	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008018	transcriptional repressor MprA; Provisional; Region: PRK10870
527001008019	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
527001008020	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
527001008021	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
527001008022	HlyD family secretion protein; Region: HlyD_3; pfam13437
527001008023	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
527001008024	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008025	putative substrate translocation pore; other site
527001008026	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008027	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
527001008028	S-ribosylhomocysteinase; Provisional; Region: PRK02260
527001008029	glutamate--cysteine ligase; Provisional; Region: PRK02107
527001008030	Predicted membrane protein [Function unknown]; Region: COG1238
527001008031	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
527001008032	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001008033	motif II; other site
527001008034	potential protein location (hypothetical protein TY21A_13780 [Salmonella enterica subsp. enterica serovar Typhi str. Ty21]) that overlaps RNA (tRNA-R)
527001008035	carbon storage regulator; Provisional; Region: PRK01712
527001008036	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
527001008037	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
527001008038	motif 1; other site
527001008039	active site
527001008040	motif 2; other site
527001008041	motif 3; other site
527001008042	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
527001008043	DHHA1 domain; Region: DHHA1; pfam02272
527001008044	recombination regulator RecX; Reviewed; Region: recX; PRK00117
527001008045	recombinase A; Provisional; Region: recA; PRK09354
527001008046	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
527001008047	hexamer interface [polypeptide binding]; other site
527001008048	Walker A motif; other site
527001008049	ATP binding site [chemical binding]; other site
527001008050	Walker B motif; other site
527001008051	hypothetical protein; Validated; Region: PRK03661
527001008052	Transglycosylase SLT domain; Region: SLT_2; pfam13406
527001008053	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
527001008054	N-acetyl-D-glucosamine binding site [chemical binding]; other site
527001008055	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
527001008056	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
527001008057	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
527001008058	Nucleoside recognition; Region: Gate; pfam07670
527001008059	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
527001008060	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
527001008061	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
527001008062	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
527001008063	putative NAD(P) binding site [chemical binding]; other site
527001008064	active site
527001008065	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
527001008066	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
527001008067	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
527001008068	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001008069	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
527001008070	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
527001008071	putative active site [active]
527001008072	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
527001008073	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
527001008074	GAF domain; Region: GAF; pfam01590
527001008075	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001008076	Walker A motif; other site
527001008077	ATP binding site [chemical binding]; other site
527001008078	Walker B motif; other site
527001008079	arginine finger; other site
527001008080	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
527001008081	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
527001008082	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
527001008083	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
527001008084	iron binding site [ion binding]; other site
527001008085	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
527001008086	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
527001008087	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001008088	Acylphosphatase; Region: Acylphosphatase; pfam00708
527001008089	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
527001008090	HypF finger; Region: zf-HYPF; pfam07503
527001008091	HypF finger; Region: zf-HYPF; pfam07503
527001008092	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
527001008093	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
527001008094	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
527001008095	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
527001008096	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
527001008097	nickel binding site [ion binding]; other site
527001008098	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
527001008099	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
527001008100	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
527001008101	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
527001008102	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
527001008103	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
527001008104	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
527001008105	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
527001008106	NADH dehydrogenase; Region: NADHdh; cl00469
527001008107	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
527001008108	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
527001008109	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
527001008110	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
527001008111	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
527001008112	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
527001008113	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
527001008114	hydrogenase assembly chaperone; Provisional; Region: PRK10409
527001008115	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
527001008116	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
527001008117	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
527001008118	dimerization interface [polypeptide binding]; other site
527001008119	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
527001008120	ATP binding site [chemical binding]; other site
527001008121	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
527001008122	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
527001008123	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
527001008124	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001008125	Walker A motif; other site
527001008126	ATP binding site [chemical binding]; other site
527001008127	Walker B motif; other site
527001008128	arginine finger; other site
527001008129	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
527001008130	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
527001008131	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
527001008132	metal binding site [ion binding]; metal-binding site
527001008133	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
527001008134	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
527001008135	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
527001008136	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
527001008137	ABC-ATPase subunit  interface; other site
527001008138	dimer interface [polypeptide binding]; other site
527001008139	putative PBP binding regions; other site
527001008140	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
527001008141	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
527001008142	ABC-ATPase subunit  interface; other site
527001008143	dimer interface [polypeptide binding]; other site
527001008144	putative PBP binding regions; other site
527001008145	transcriptional activator SprB; Provisional; Region: PRK15320
527001008146	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
527001008147	transcriptional regulator SirC; Provisional; Region: PRK15044
527001008148	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001008149	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
527001008150	invasion protein OrgB; Provisional; Region: PRK15322
527001008151	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
527001008152	invasion protein OrgA; Provisional; Region: PRK15323
527001008153	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
527001008154	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
527001008155	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
527001008156	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
527001008157	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
527001008158	transcriptional regulator HilD; Provisional; Region: PRK15185
527001008159	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001008160	invasion protein regulator; Provisional; Region: PRK12370
527001008161	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001008162	DNA binding site [nucleotide binding]
527001008163	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
527001008164	binding surface
527001008165	TPR motif; other site
527001008166	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
527001008167	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
527001008168	N-acetyl-D-glucosamine binding site [chemical binding]; other site
527001008169	catalytic residue [active]
527001008170	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
527001008171	SicP binding; Region: SicP-binding; pfam09119
527001008172	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
527001008173	switch II binding region; other site
527001008174	Rac1 P-loop interaction site [polypeptide binding]; other site
527001008175	GTP binding residues [chemical binding]; other site
527001008176	switch I binding region; other site
527001008177	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
527001008178	active site
527001008179	chaperone protein SicP; Provisional; Region: PRK15329
527001008180	putative acyl carrier protein IacP; Validated; Region: PRK08172
527001008181	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
527001008182	cell invasion protein SipD; Provisional; Region: PRK15330
527001008183	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
527001008184	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
527001008185	chaperone protein SicA; Provisional; Region: PRK15331
527001008186	Tetratricopeptide repeat; Region: TPR_3; pfam07720
527001008187	Tetratricopeptide repeat; Region: TPR_3; pfam07720
527001008188	type III secretion system protein SpaS; Validated; Region: PRK08156
527001008189	type III secretion system protein SpaR; Provisional; Region: PRK15332
527001008190	type III secretion system protein SpaQ; Provisional; Region: PRK15333
527001008191	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
527001008192	type III secretion system protein SpaO; Validated; Region: PRK08158
527001008193	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
527001008194	antigen presentation protein SpaN; Provisional; Region: PRK15334
527001008195	Surface presentation of antigens protein; Region: SPAN; pfam02510
527001008196	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
527001008197	ATP synthase SpaL; Validated; Region: PRK08149
527001008198	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
527001008199	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
527001008200	Walker A motif; other site
527001008201	ATP binding site [chemical binding]; other site
527001008202	Walker B motif; other site
527001008203	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
527001008204	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
527001008205	type III secretion system protein InvA; Provisional; Region: PRK15337
527001008206	type III secretion system regulator InvE; Provisional; Region: PRK15338
527001008207	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
527001008208	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
527001008209	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
527001008210	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
527001008211	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
527001008212	transcriptional regulator InvF; Provisional; Region: PRK15340
527001008213	InvH outer membrane lipoprotein; Region: InvH; pfam04741
527001008214	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
527001008215	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
527001008216	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
527001008217	active site
527001008218	metal binding site [ion binding]; metal-binding site
527001008219	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
527001008220	MutS domain I; Region: MutS_I; pfam01624
527001008221	MutS domain II; Region: MutS_II; pfam05188
527001008222	MutS domain III; Region: MutS_III; pfam05192
527001008223	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
527001008224	Walker A/P-loop; other site
527001008225	ATP binding site [chemical binding]; other site
527001008226	Q-loop/lid; other site
527001008227	ABC transporter signature motif; other site
527001008228	Walker B; other site
527001008229	D-loop; other site
527001008230	H-loop/switch region; other site
527001008231	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
527001008232	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008233	Major Facilitator Superfamily; Region: MFS_1; pfam07690
527001008234	putative substrate translocation pore; other site
527001008235	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001008236	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001008237	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
527001008238	putative effector binding pocket; other site
527001008239	dimerization interface [polypeptide binding]; other site
527001008240	GntP family permease; Region: GntP_permease; pfam02447
527001008241	fructuronate transporter; Provisional; Region: PRK10034; cl15264
527001008242	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
527001008243	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
527001008244	putative NAD(P) binding site [chemical binding]; other site
527001008245	active site
527001008246	putative substrate binding site [chemical binding]; other site
527001008247	hypothetical protein; Provisional; Region: PRK09989
527001008248	putative aldolase; Validated; Region: PRK08130
527001008249	intersubunit interface [polypeptide binding]; other site
527001008250	active site
527001008251	Zn2+ binding site [ion binding]; other site
527001008252	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
527001008253	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
527001008254	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
527001008255	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
527001008256	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
527001008257	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001008258	MarR family; Region: MarR_2; cl17246
527001008259	Transcriptional regulators [Transcription]; Region: MarR; COG1846
527001008260	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
527001008261	Flavoprotein; Region: Flavoprotein; pfam02441
527001008262	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
527001008263	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
527001008264	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
527001008265	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
527001008266	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
527001008267	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
527001008268	DNA binding residues [nucleotide binding]
527001008269	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
527001008270	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
527001008271	Peptidase family M23; Region: Peptidase_M23; pfam01551
527001008272	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
527001008273	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001008274	S-adenosylmethionine binding site [chemical binding]; other site
527001008275	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
527001008276	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
527001008277	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
527001008278	Permutation of conserved domain; other site
527001008279	active site
527001008280	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
527001008281	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
527001008282	homotrimer interaction site [polypeptide binding]; other site
527001008283	zinc binding site [ion binding]; other site
527001008284	CDP-binding sites; other site
527001008285	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
527001008286	substrate binding site; other site
527001008287	dimer interface; other site
527001008288	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
527001008289	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
527001008290	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
527001008291	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
527001008292	ligand-binding site [chemical binding]; other site
527001008293	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
527001008294	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
527001008295	CysD dimerization site [polypeptide binding]; other site
527001008296	G1 box; other site
527001008297	putative GEF interaction site [polypeptide binding]; other site
527001008298	GTP/Mg2+ binding site [chemical binding]; other site
527001008299	Switch I region; other site
527001008300	G2 box; other site
527001008301	G3 box; other site
527001008302	Switch II region; other site
527001008303	G4 box; other site
527001008304	G5 box; other site
527001008305	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
527001008306	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
527001008307	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
527001008308	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
527001008309	Active Sites [active]
527001008310	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
527001008311	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
527001008312	metal binding site [ion binding]; metal-binding site
527001008313	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
527001008314	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
527001008315	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
527001008316	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
527001008317	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
527001008318	CT1975-like protein; Region: Cas_CT1975; pfam09344
527001008319	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
527001008320	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
527001008321	potential frameshift: common BLAST hit: gi|288933822|ref|YP_003437881.1| CRISPR-associated helicase Cas3
527001008322	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
527001008323	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
527001008324	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
527001008325	Active Sites [active]
527001008326	sulfite reductase subunit beta; Provisional; Region: PRK13504
527001008327	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
527001008328	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
527001008329	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
527001008330	Flavodoxin; Region: Flavodoxin_1; pfam00258
527001008331	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
527001008332	FAD binding pocket [chemical binding]; other site
527001008333	FAD binding motif [chemical binding]; other site
527001008334	catalytic residues [active]
527001008335	NAD binding pocket [chemical binding]; other site
527001008336	phosphate binding motif [ion binding]; other site
527001008337	beta-alpha-beta structure motif; other site
527001008338	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
527001008339	active site
527001008340	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
527001008341	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
527001008342	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
527001008343	enolase; Provisional; Region: eno; PRK00077
527001008344	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
527001008345	dimer interface [polypeptide binding]; other site
527001008346	metal binding site [ion binding]; metal-binding site
527001008347	substrate binding pocket [chemical binding]; other site
527001008348	CTP synthetase; Validated; Region: pyrG; PRK05380
527001008349	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
527001008350	Catalytic site [active]
527001008351	active site
527001008352	UTP binding site [chemical binding]; other site
527001008353	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
527001008354	active site
527001008355	putative oxyanion hole; other site
527001008356	catalytic triad [active]
527001008357	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
527001008358	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
527001008359	homodimer interface [polypeptide binding]; other site
527001008360	metal binding site [ion binding]; metal-binding site
527001008361	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
527001008362	homodimer interface [polypeptide binding]; other site
527001008363	active site
527001008364	putative chemical substrate binding site [chemical binding]; other site
527001008365	metal binding site [ion binding]; metal-binding site
527001008366	potential frameshift: common BLAST hit: gi|197248877|ref|YP_002147857.1| putative fimbrial subunit
527001008367	putative fimbrial outer membrane usher protein SteB; Provisional; Region: PRK15273
527001008368	PapC N-terminal domain; Region: PapC_N; pfam13954
527001008369	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
527001008370	PapC C-terminal domain; Region: PapC_C; pfam13953
527001008371	putative periplasmic fimbrial chaperone protein SteC; Provisional; Region: PRK15274
527001008372	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001008373	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001008374	putative fimbrial protein SteD; Provisional; Region: PRK15275
527001008375	putative fimbrial subunit SteE; Provisional; Region: PRK15276
527001008376	fimbrial protein SteF; Provisional; Region: PRK15260
527001008377	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
527001008378	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
527001008379	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
527001008380	HD domain; Region: HD_4; pfam13328
527001008381	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
527001008382	synthetase active site [active]
527001008383	NTP binding site [chemical binding]; other site
527001008384	metal binding site [ion binding]; metal-binding site
527001008385	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
527001008386	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
527001008387	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
527001008388	TRAM domain; Region: TRAM; pfam01938
527001008389	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001008390	S-adenosylmethionine binding site [chemical binding]; other site
527001008391	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
527001008392	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
527001008393	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001008394	dimerization interface [polypeptide binding]; other site
527001008395	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001008396	dimer interface [polypeptide binding]; other site
527001008397	phosphorylation site [posttranslational modification]
527001008398	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001008399	ATP binding site [chemical binding]; other site
527001008400	Mg2+ binding site [ion binding]; other site
527001008401	G-X-G motif; other site
527001008402	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
527001008403	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001008404	active site
527001008405	phosphorylation site [posttranslational modification]
527001008406	intermolecular recognition site; other site
527001008407	dimerization interface [polypeptide binding]; other site
527001008408	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
527001008409	putative binding surface; other site
527001008410	active site
527001008411	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
527001008412	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
527001008413	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
527001008414	active site
527001008415	tetramer interface [polypeptide binding]; other site
527001008416	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
527001008417	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
527001008418	active site
527001008419	tetramer interface [polypeptide binding]; other site
527001008420	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008421	D-galactonate transporter; Region: 2A0114; TIGR00893
527001008422	putative substrate translocation pore; other site
527001008423	flavodoxin; Provisional; Region: PRK08105
527001008424	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
527001008425	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
527001008426	probable active site [active]
527001008427	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
527001008428	SecY interacting protein Syd; Provisional; Region: PRK04968
527001008429	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
527001008430	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
527001008431	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
527001008432	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
527001008433	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
527001008434	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
527001008435	serine transporter; Region: stp; TIGR00814
527001008436	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
527001008437	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
527001008438	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
527001008439	flap endonuclease-like protein; Provisional; Region: PRK09482
527001008440	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
527001008441	active site
527001008442	metal binding site 1 [ion binding]; metal-binding site
527001008443	putative 5' ssDNA interaction site; other site
527001008444	metal binding site 3; metal-binding site
527001008445	metal binding site 2 [ion binding]; metal-binding site
527001008446	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
527001008447	putative DNA binding site [nucleotide binding]; other site
527001008448	putative metal binding site [ion binding]; other site
527001008449	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
527001008450	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
527001008451	dimer interface [polypeptide binding]; other site
527001008452	active site
527001008453	metal binding site [ion binding]; metal-binding site
527001008454	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
527001008455	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
527001008456	intersubunit interface [polypeptide binding]; other site
527001008457	active site
527001008458	Zn2+ binding site [ion binding]; other site
527001008459	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
527001008460	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008461	putative substrate translocation pore; other site
527001008462	L-fucose isomerase; Provisional; Region: fucI; PRK10991
527001008463	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
527001008464	hexamer (dimer of trimers) interface [polypeptide binding]; other site
527001008465	trimer interface [polypeptide binding]; other site
527001008466	substrate binding site [chemical binding]; other site
527001008467	Mn binding site [ion binding]; other site
527001008468	L-fuculokinase; Provisional; Region: PRK10331
527001008469	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
527001008470	nucleotide binding site [chemical binding]; other site
527001008471	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
527001008472	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
527001008473	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
527001008474	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001008475	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
527001008476	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
527001008477	hypothetical protein; Provisional; Region: PRK10873
527001008478	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
527001008479	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001008480	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
527001008481	dimerization interface [polypeptide binding]; other site
527001008482	substrate binding pocket [chemical binding]; other site
527001008483	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
527001008484	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
527001008485	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
527001008486	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
527001008487	catalytic residue [active]
527001008488	CsdA-binding activator; Provisional; Region: PRK15019
527001008489	Predicted permeases [General function prediction only]; Region: RarD; COG2962
527001008490	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
527001008491	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
527001008492	putative ATP binding site [chemical binding]; other site
527001008493	putative substrate interface [chemical binding]; other site
527001008494	murein transglycosylase A; Provisional; Region: mltA; PRK11162
527001008495	murein hydrolase B; Provisional; Region: PRK10760; cl17906
527001008496	MltA specific insert domain; Region: MltA; pfam03562
527001008497	3D domain; Region: 3D; pfam06725
527001008498	AMIN domain; Region: AMIN; pfam11741
527001008499	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
527001008500	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
527001008501	active site
527001008502	metal binding site [ion binding]; metal-binding site
527001008503	N-acetylglutamate synthase; Validated; Region: PRK05279
527001008504	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
527001008505	putative feedback inhibition sensing region; other site
527001008506	putative nucleotide binding site [chemical binding]; other site
527001008507	putative substrate binding site [chemical binding]; other site
527001008508	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001008509	Coenzyme A binding pocket [chemical binding]; other site
527001008510	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
527001008511	AAA domain; Region: AAA_30; pfam13604
527001008512	Family description; Region: UvrD_C_2; pfam13538
527001008513	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
527001008514	protease3; Provisional; Region: PRK15101
527001008515	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
527001008516	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
527001008517	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
527001008518	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
527001008519	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
527001008520	hypothetical protein; Provisional; Region: PRK10332
527001008521	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
527001008522	hypothetical protein; Provisional; Region: PRK11521
527001008523	hypothetical protein; Provisional; Region: PRK10557
527001008524	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
527001008525	hypothetical protein; Provisional; Region: PRK10506
527001008526	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
527001008527	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001008528	thymidylate synthase; Reviewed; Region: thyA; PRK01827
527001008529	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
527001008530	dimerization interface [polypeptide binding]; other site
527001008531	active site
527001008532	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
527001008533	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
527001008534	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
527001008535	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
527001008536	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
527001008537	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
527001008538	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
527001008539	putative active site [active]
527001008540	Ap4A binding site [chemical binding]; other site
527001008541	nudix motif; other site
527001008542	putative metal binding site [ion binding]; other site
527001008543	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
527001008544	putative DNA-binding cleft [nucleotide binding]; other site
527001008545	putative DNA clevage site; other site
527001008546	molecular lever; other site
527001008547	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
527001008548	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
527001008549	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
527001008550	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
527001008551	active site
527001008552	catalytic tetrad [active]
527001008553	lysophospholipid transporter LplT; Provisional; Region: PRK11195
527001008554	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008555	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
527001008556	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
527001008557	putative acyl-acceptor binding pocket; other site
527001008558	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
527001008559	acyl-activating enzyme (AAE) consensus motif; other site
527001008560	putative AMP binding site [chemical binding]; other site
527001008561	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001008562	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
527001008563	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001008564	DNA binding site [nucleotide binding]
527001008565	domain linker motif; other site
527001008566	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
527001008567	dimerization interface (closed form) [polypeptide binding]; other site
527001008568	ligand binding site [chemical binding]; other site
527001008569	Transcriptional regulators [Transcription]; Region: PurR; COG1609
527001008570	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001008571	DNA binding site [nucleotide binding]
527001008572	domain linker motif; other site
527001008573	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
527001008574	dimerization interface (closed form) [polypeptide binding]; other site
527001008575	ligand binding site [chemical binding]; other site
527001008576	diaminopimelate decarboxylase; Provisional; Region: PRK11165
527001008577	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
527001008578	active site
527001008579	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
527001008580	substrate binding site [chemical binding]; other site
527001008581	catalytic residues [active]
527001008582	dimer interface [polypeptide binding]; other site
527001008583	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
527001008584	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001008585	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
527001008586	dimerization interface [polypeptide binding]; other site
527001008587	putative racemase; Provisional; Region: PRK10200
527001008588	aspartate racemase; Region: asp_race; TIGR00035
527001008589	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
527001008590	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008591	putative substrate translocation pore; other site
527001008592	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008593	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
527001008594	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
527001008595	NADP binding site [chemical binding]; other site
527001008596	homodimer interface [polypeptide binding]; other site
527001008597	active site
527001008598	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
527001008599	putative acyltransferase; Provisional; Region: PRK05790
527001008600	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
527001008601	dimer interface [polypeptide binding]; other site
527001008602	active site
527001008603	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001008604	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001008605	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
527001008606	dimerization interface [polypeptide binding]; other site
527001008607	Predicted membrane protein [Function unknown]; Region: COG4125
527001008608	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
527001008609	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
527001008610	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
527001008611	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
527001008612	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
527001008613	putative metal binding site [ion binding]; other site
527001008614	putative homodimer interface [polypeptide binding]; other site
527001008615	putative homotetramer interface [polypeptide binding]; other site
527001008616	putative homodimer-homodimer interface [polypeptide binding]; other site
527001008617	putative allosteric switch controlling residues; other site
527001008618	potential frameshift: common BLAST hit: gi|198244004|ref|YP_002217001.1| nickel/cobalt efflux protein RcnA
527001008619	transcriptional activator SprB; Provisional; Region: PRK15320
527001008620	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14600
527001008621	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
527001008622	Fimbrial protein; Region: Fimbrial; pfam00419
527001008623	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
527001008624	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001008625	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001008626	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
527001008627	PapC N-terminal domain; Region: PapC_N; pfam13954
527001008628	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
527001008629	PapC C-terminal domain; Region: PapC_C; pfam13953
527001008630	fimbrial protein StdA; Provisional; Region: PRK15210
527001008631	hypothetical protein; Provisional; Region: PRK10316
527001008632	YfdX protein; Region: YfdX; pfam10938
527001008633	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
527001008634	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
527001008635	oligomeric interface; other site
527001008636	putative active site [active]
527001008637	homodimer interface [polypeptide binding]; other site
527001008638	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
527001008639	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
527001008640	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
527001008641	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
527001008642	INT_SG2, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 2, C-terminal catalytic domain. The CD contains mainly predicted integrase/recombinases and phage-related integrases. Some have N-terminal domains, which show little sequence...; Region: INT_SG2_C; cd01184
527001008643	Int/Topo IB signature motif; other site
527001008644	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
527001008645	Peptidase family M23; Region: Peptidase_M23; pfam01551
527001008646	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
527001008647	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
527001008648	active site
527001008649	metal binding site [ion binding]; metal-binding site
527001008650	nudix motif; other site
527001008651	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
527001008652	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
527001008653	dimer interface [polypeptide binding]; other site
527001008654	putative anticodon binding site; other site
527001008655	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
527001008656	motif 1; other site
527001008657	active site
527001008658	motif 2; other site
527001008659	motif 3; other site
527001008660	This domain is found in peptide chain release factors; Region: PCRF; smart00937
527001008661	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
527001008662	RF-1 domain; Region: RF-1; pfam00472
527001008663	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
527001008664	DHH family; Region: DHH; pfam01368
527001008665	DHHA1 domain; Region: DHHA1; pfam02272
527001008666	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
527001008667	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
527001008668	dimerization domain [polypeptide binding]; other site
527001008669	dimer interface [polypeptide binding]; other site
527001008670	catalytic residues [active]
527001008671	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
527001008672	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
527001008673	active site
527001008674	Int/Topo IB signature motif; other site
527001008675	flavodoxin FldB; Provisional; Region: PRK12359
527001008676	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
527001008677	hypothetical protein; Provisional; Region: PRK10878
527001008678	putative global regulator; Reviewed; Region: PRK09559
527001008679	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
527001008680	hemolysin; Provisional; Region: PRK15087
527001008681	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
527001008682	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
527001008683	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
527001008684	beta-galactosidase; Region: BGL; TIGR03356
527001008685	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
527001008686	glycine dehydrogenase; Provisional; Region: PRK05367
527001008687	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
527001008688	tetramer interface [polypeptide binding]; other site
527001008689	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001008690	catalytic residue [active]
527001008691	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
527001008692	tetramer interface [polypeptide binding]; other site
527001008693	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001008694	catalytic residue [active]
527001008695	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
527001008696	lipoyl attachment site [posttranslational modification]; other site
527001008697	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
527001008698	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
527001008699	oxidoreductase; Provisional; Region: PRK08013
527001008700	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
527001008701	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
527001008702	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
527001008703	proline aminopeptidase P II; Provisional; Region: PRK10879
527001008704	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
527001008705	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
527001008706	active site
527001008707	hypothetical protein; Reviewed; Region: PRK01736
527001008708	Z-ring-associated protein; Provisional; Region: PRK10972
527001008709	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
527001008710	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
527001008711	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
527001008712	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
527001008713	ligand binding site [chemical binding]; other site
527001008714	NAD binding site [chemical binding]; other site
527001008715	tetramer interface [polypeptide binding]; other site
527001008716	catalytic site [active]
527001008717	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
527001008718	L-serine binding site [chemical binding]; other site
527001008719	ACT domain interface; other site
527001008720	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
527001008721	tetramer (dimer of dimers) interface [polypeptide binding]; other site
527001008722	active site
527001008723	dimer interface [polypeptide binding]; other site
527001008724	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
527001008725	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001008726	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
527001008727	putative dimerization interface [polypeptide binding]; other site
527001008728	Uncharacterized conserved protein [Function unknown]; Region: COG2968
527001008729	oxidative stress defense protein; Provisional; Region: PRK11087
527001008730	arginine exporter protein; Provisional; Region: PRK09304
527001008731	mechanosensitive channel MscS; Provisional; Region: PRK10334
527001008732	Mechanosensitive ion channel; Region: MS_channel; pfam00924
527001008733	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001008734	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
527001008735	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
527001008736	active site
527001008737	intersubunit interface [polypeptide binding]; other site
527001008738	zinc binding site [ion binding]; other site
527001008739	Na+ binding site [ion binding]; other site
527001008740	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
527001008741	Phosphoglycerate kinase; Region: PGK; pfam00162
527001008742	substrate binding site [chemical binding]; other site
527001008743	hinge regions; other site
527001008744	ADP binding site [chemical binding]; other site
527001008745	catalytic site [active]
527001008746	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
527001008747	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
527001008748	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
527001008749	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
527001008750	trimer interface [polypeptide binding]; other site
527001008751	putative Zn binding site [ion binding]; other site
527001008752	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
527001008753	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
527001008754	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
527001008755	Walker A/P-loop; other site
527001008756	ATP binding site [chemical binding]; other site
527001008757	Q-loop/lid; other site
527001008758	ABC transporter signature motif; other site
527001008759	Walker B; other site
527001008760	D-loop; other site
527001008761	H-loop/switch region; other site
527001008762	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
527001008763	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
527001008764	Walker A/P-loop; other site
527001008765	ATP binding site [chemical binding]; other site
527001008766	Q-loop/lid; other site
527001008767	ABC transporter signature motif; other site
527001008768	Walker B; other site
527001008769	D-loop; other site
527001008770	H-loop/switch region; other site
527001008771	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001008772	transketolase; Reviewed; Region: PRK12753
527001008773	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
527001008774	TPP-binding site [chemical binding]; other site
527001008775	dimer interface [polypeptide binding]; other site
527001008776	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
527001008777	PYR/PP interface [polypeptide binding]; other site
527001008778	dimer interface [polypeptide binding]; other site
527001008779	TPP binding site [chemical binding]; other site
527001008780	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
527001008781	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
527001008782	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
527001008783	agmatinase; Region: agmatinase; TIGR01230
527001008784	oligomer interface [polypeptide binding]; other site
527001008785	putative active site [active]
527001008786	Mn binding site [ion binding]; other site
527001008787	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
527001008788	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
527001008789	dimer interface [polypeptide binding]; other site
527001008790	active site
527001008791	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
527001008792	catalytic residues [active]
527001008793	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
527001008794	Virulence promoting factor; Region: YqgB; pfam11036
527001008795	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
527001008796	S-adenosylmethionine synthetase; Validated; Region: PRK05250
527001008797	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
527001008798	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
527001008799	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
527001008800	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
527001008801	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008802	putative substrate translocation pore; other site
527001008803	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008804	hypothetical protein; Provisional; Region: PRK04860
527001008805	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
527001008806	DNA-specific endonuclease I; Provisional; Region: PRK15137
527001008807	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
527001008808	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
527001008809	RNA methyltransferase, RsmE family; Region: TIGR00046
527001008810	glutathione synthetase; Provisional; Region: PRK05246
527001008811	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
527001008812	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
527001008813	hypothetical protein; Validated; Region: PRK00228
527001008814	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
527001008815	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
527001008816	Transcriptional regulator [Transcription]; Region: IclR; COG1414
527001008817	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
527001008818	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
527001008819	Walker A motif; other site
527001008820	ATP binding site [chemical binding]; other site
527001008821	Walker B motif; other site
527001008822	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
527001008823	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
527001008824	catalytic residue [active]
527001008825	YGGT family; Region: YGGT; pfam02325
527001008826	YGGT family; Region: YGGT; pfam02325
527001008827	hypothetical protein; Validated; Region: PRK05090
527001008828	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
527001008829	active site
527001008830	dimerization interface [polypeptide binding]; other site
527001008831	HemN family oxidoreductase; Provisional; Region: PRK05660
527001008832	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001008833	FeS/SAM binding site; other site
527001008834	HemN C-terminal domain; Region: HemN_C; pfam06969
527001008835	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
527001008836	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
527001008837	homodimer interface [polypeptide binding]; other site
527001008838	active site
527001008839	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001008840	hypothetical protein; Provisional; Region: PRK10626
527001008841	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
527001008842	hypothetical protein; Provisional; Region: PRK11702
527001008843	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
527001008844	adenine DNA glycosylase; Provisional; Region: PRK10880
527001008845	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
527001008846	minor groove reading motif; other site
527001008847	helix-hairpin-helix signature motif; other site
527001008848	substrate binding pocket [chemical binding]; other site
527001008849	active site
527001008850	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
527001008851	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
527001008852	DNA binding and oxoG recognition site [nucleotide binding]
527001008853	oxidative damage protection protein; Provisional; Region: PRK05408
527001008854	murein transglycosylase C; Provisional; Region: mltC; PRK11671
527001008855	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
527001008856	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
527001008857	N-acetyl-D-glucosamine binding site [chemical binding]; other site
527001008858	catalytic residue [active]
527001008859	nucleoside transporter; Region: 2A0110; TIGR00889
527001008860	potential frameshift: common BLAST hit: gi|197249160|ref|YP_002148029.1| ornithine decarboxylase
527001008861	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
527001008862	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
527001008863	PAAR motif; Region: PAAR_motif; pfam05488
527001008864	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
527001008865	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
527001008866	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
527001008867	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
527001008868	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
527001008869	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001008870	DNA binding residues [nucleotide binding]
527001008871	dimerization interface [polypeptide binding]; other site
527001008872	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
527001008873	Amino acid permease; Region: AA_permease_2; pfam13520
527001008874	Protein of unknown function (DUF861); Region: Cupin_3; cl17594
527001008875	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
527001008876	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
527001008877	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
527001008878	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
527001008879	NAD(P) binding site [chemical binding]; other site
527001008880	catalytic residues [active]
527001008881	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
527001008882	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
527001008883	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
527001008884	active site
527001008885	catalytic site [active]
527001008886	Zn binding site [ion binding]; other site
527001008887	tetramer interface [polypeptide binding]; other site
527001008888	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
527001008889	Predicted amidohydrolase [General function prediction only]; Region: COG0388
527001008890	active site
527001008891	catalytic triad [active]
527001008892	dimer interface [polypeptide binding]; other site
527001008893	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001008894	D-galactonate transporter; Region: 2A0114; TIGR00893
527001008895	putative substrate translocation pore; other site
527001008896	mannonate dehydratase; Provisional; Region: PRK03906
527001008897	mannonate dehydratase; Region: uxuA; TIGR00695
527001008898	D-mannonate oxidoreductase; Provisional; Region: PRK15037
527001008899	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
527001008900	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
527001008901	Glucuronate isomerase; Region: UxaC; pfam02614
527001008902	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
527001008903	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
527001008904	dimer interface [polypeptide binding]; other site
527001008905	putative CheW interface [polypeptide binding]; other site
527001008906	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
527001008907	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
527001008908	CHAP domain; Region: CHAP; pfam05257
527001008909	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
527001008910	putative S-transferase; Provisional; Region: PRK11752
527001008911	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
527001008912	C-terminal domain interface [polypeptide binding]; other site
527001008913	GSH binding site (G-site) [chemical binding]; other site
527001008914	dimer interface [polypeptide binding]; other site
527001008915	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
527001008916	dimer interface [polypeptide binding]; other site
527001008917	N-terminal domain interface [polypeptide binding]; other site
527001008918	active site
527001008919	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
527001008920	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
527001008921	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
527001008922	putative ligand binding residues [chemical binding]; other site
527001008923	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
527001008924	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
527001008925	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
527001008926	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
527001008927	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
527001008928	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
527001008929	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
527001008930	putative substrate-binding site; other site
527001008931	nickel binding site [ion binding]; other site
527001008932	hydrogenase 2 large subunit; Provisional; Region: PRK10467
527001008933	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
527001008934	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
527001008935	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
527001008936	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
527001008937	4Fe-4S binding domain; Region: Fer4_6; pfam12837
527001008938	hydrogenase 2 small subunit; Provisional; Region: PRK10468
527001008939	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
527001008940	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
527001008941	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
527001008942	potential frameshift: common BLAST hit: gi|194443141|ref|YP_002042417.1| methyl-accepting chemotaxis sensory transducer
527001008943	hypothetical protein; Provisional; Region: PRK05208
527001008944	oxidoreductase; Provisional; Region: PRK07985
527001008945	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
527001008946	NAD binding site [chemical binding]; other site
527001008947	metal binding site [ion binding]; metal-binding site
527001008948	active site
527001008949	biopolymer transport protein ExbD; Provisional; Region: PRK11267
527001008950	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
527001008951	biopolymer transport protein ExbB; Provisional; Region: PRK10414
527001008952	cystathionine beta-lyase; Provisional; Region: PRK08114
527001008953	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
527001008954	homodimer interface [polypeptide binding]; other site
527001008955	substrate-cofactor binding pocket; other site
527001008956	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001008957	catalytic residue [active]
527001008958	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
527001008959	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
527001008960	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
527001008961	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
527001008962	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001008963	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001008964	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
527001008965	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
527001008966	dimer interface [polypeptide binding]; other site
527001008967	active site
527001008968	metal binding site [ion binding]; metal-binding site
527001008969	potential frameshift: common BLAST hit: gi|224584963|ref|YP_002638762.1| 2,5-diketo-D-gluconate reductase A
527001008970	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
527001008971	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
527001008972	transmembrane helices; other site
527001008973	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
527001008974	nucleotide binding site/active site [active]
527001008975	catalytic residue [active]
527001008976	hypothetical protein; Provisional; Region: PRK01254
527001008977	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
527001008978	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
527001008979	YARHG domain; Region: YARHG; pfam13308
527001008980	FtsI repressor; Provisional; Region: PRK10883
527001008981	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
527001008982	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
527001008983	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
527001008984	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
527001008985	putative acyl-acceptor binding pocket; other site
527001008986	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
527001008987	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
527001008988	CAP-like domain; other site
527001008989	active site
527001008990	primary dimer interface [polypeptide binding]; other site
527001008991	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
527001008992	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
527001008993	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001008994	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
527001008995	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
527001008996	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
527001008997	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001008998	active site
527001008999	phosphorylation site [posttranslational modification]
527001009000	intermolecular recognition site; other site
527001009001	dimerization interface [polypeptide binding]; other site
527001009002	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001009003	DNA binding site [nucleotide binding]
527001009004	sensor protein QseC; Provisional; Region: PRK10337
527001009005	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
527001009006	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001009007	dimer interface [polypeptide binding]; other site
527001009008	phosphorylation site [posttranslational modification]
527001009009	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001009010	ATP binding site [chemical binding]; other site
527001009011	Mg2+ binding site [ion binding]; other site
527001009012	G-X-G motif; other site
527001009013	potential frameshift: common BLAST hit: gi|197251739|ref|YP_002148106.1| NADPH-specific quinone oxidoreductase
527001009014	Uncharacterized conserved protein [Function unknown]; Region: COG1359
527001009015	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
527001009016	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001009017	ATP binding site [chemical binding]; other site
527001009018	Mg2+ binding site [ion binding]; other site
527001009019	G-X-G motif; other site
527001009020	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
527001009021	anchoring element; other site
527001009022	dimer interface [polypeptide binding]; other site
527001009023	ATP binding site [chemical binding]; other site
527001009024	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
527001009025	active site
527001009026	metal binding site [ion binding]; metal-binding site
527001009027	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
527001009028	esterase YqiA; Provisional; Region: PRK11071
527001009029	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
527001009030	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
527001009031	active site
527001009032	metal binding site [ion binding]; metal-binding site
527001009033	hexamer interface [polypeptide binding]; other site
527001009034	putative dehydrogenase; Provisional; Region: PRK11039
527001009035	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
527001009036	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
527001009037	dimer interface [polypeptide binding]; other site
527001009038	ADP-ribose binding site [chemical binding]; other site
527001009039	active site
527001009040	nudix motif; other site
527001009041	metal binding site [ion binding]; metal-binding site
527001009042	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
527001009043	hypothetical protein; Provisional; Region: PRK11653
527001009044	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
527001009045	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
527001009046	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
527001009047	putative active site [active]
527001009048	metal binding site [ion binding]; metal-binding site
527001009049	zinc transporter ZupT; Provisional; Region: PRK04201
527001009050	ZIP Zinc transporter; Region: Zip; pfam02535
527001009051	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
527001009052	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
527001009053	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
527001009054	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
527001009055	catalytic residues [active]
527001009056	hinge region; other site
527001009057	alpha helical domain; other site
527001009058	putative disulfide oxidoreductase; Provisional; Region: PRK04307
527001009059	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
527001009060	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
527001009061	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
527001009062	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
527001009063	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
527001009064	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
527001009065	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
527001009066	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
527001009067	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
527001009068	putative ribose interaction site [chemical binding]; other site
527001009069	putative ADP binding site [chemical binding]; other site
527001009070	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
527001009071	active site
527001009072	nucleotide binding site [chemical binding]; other site
527001009073	HIGH motif; other site
527001009074	KMSKS motif; other site
527001009075	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
527001009076	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
527001009077	metal binding triad; other site
527001009078	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
527001009079	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
527001009080	metal binding triad; other site
527001009081	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
527001009082	Uncharacterized conserved protein [Function unknown]; Region: COG3025
527001009083	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
527001009084	putative active site [active]
527001009085	putative metal binding residues [ion binding]; other site
527001009086	signature motif; other site
527001009087	putative triphosphate binding site [ion binding]; other site
527001009088	CHAD domain; Region: CHAD; pfam05235
527001009089	SH3 domain-containing protein; Provisional; Region: PRK10884
527001009090	Bacterial SH3 domain homologues; Region: SH3b; smart00287
527001009091	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
527001009092	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
527001009093	active site
527001009094	NTP binding site [chemical binding]; other site
527001009095	metal binding triad [ion binding]; metal-binding site
527001009096	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
527001009097	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
527001009098	Zn2+ binding site [ion binding]; other site
527001009099	Mg2+ binding site [ion binding]; other site
527001009100	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
527001009101	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
527001009102	homooctamer interface [polypeptide binding]; other site
527001009103	active site
527001009104	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
527001009105	Fumarate hydratase (Fumerase); Region: Fumerase; cl00851
527001009106	UGMP family protein; Validated; Region: PRK09604
527001009107	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
527001009108	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
527001009109	DNA primase; Validated; Region: dnaG; PRK05667
527001009110	CHC2 zinc finger; Region: zf-CHC2; pfam01807
527001009111	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
527001009112	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
527001009113	active site
527001009114	metal binding site [ion binding]; metal-binding site
527001009115	interdomain interaction site; other site
527001009116	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
527001009117	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
527001009118	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
527001009119	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
527001009120	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
527001009121	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
527001009122	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
527001009123	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
527001009124	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
527001009125	DNA binding residues [nucleotide binding]
527001009126	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
527001009127	active site
527001009128	SUMO-1 interface [polypeptide binding]; other site
527001009129	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
527001009130	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
527001009131	FAD binding pocket [chemical binding]; other site
527001009132	FAD binding motif [chemical binding]; other site
527001009133	phosphate binding motif [ion binding]; other site
527001009134	NAD binding pocket [chemical binding]; other site
527001009135	Predicted transcriptional regulators [Transcription]; Region: COG1695
527001009136	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
527001009137	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
527001009138	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001009139	dimerization interface [polypeptide binding]; other site
527001009140	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
527001009141	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
527001009142	dimer interface [polypeptide binding]; other site
527001009143	putative CheW interface [polypeptide binding]; other site
527001009144	PAS fold; Region: PAS_3; pfam08447
527001009145	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
527001009146	putative active site [active]
527001009147	heme pocket [chemical binding]; other site
527001009148	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
527001009149	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
527001009150	dimer interface [polypeptide binding]; other site
527001009151	putative CheW interface [polypeptide binding]; other site
527001009152	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
527001009153	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
527001009154	inhibitor-cofactor binding pocket; inhibition site
527001009155	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001009156	catalytic residue [active]
527001009157	potential frameshift: common BLAST hit: gi|197364088|ref|YP_002143725.1| 2,4-dieonyl-coa reductase
527001009158	potential frameshift: common BLAST hit: gi|194444842|ref|YP_002042486.1| FAD/FMN-binding/pyridine nucleotide-disulphide oxidoreductase
527001009159	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
527001009160	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001009161	S-adenosylmethionine binding site [chemical binding]; other site
527001009162	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
527001009163	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
527001009164	putative active site [active]
527001009165	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
527001009166	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
527001009167	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
527001009168	serine/threonine transporter SstT; Provisional; Region: PRK13628
527001009169	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
527001009170	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
527001009171	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
527001009172	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
527001009173	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
527001009174	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
527001009175	Predicted membrane protein [Function unknown]; Region: COG5393
527001009176	YqjK-like protein; Region: YqjK; pfam13997
527001009177	Predicted membrane protein [Function unknown]; Region: COG2259
527001009178	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
527001009179	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
527001009180	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
527001009181	putative dimer interface [polypeptide binding]; other site
527001009182	N-terminal domain interface [polypeptide binding]; other site
527001009183	putative substrate binding pocket (H-site) [chemical binding]; other site
527001009184	Predicted membrane protein [Function unknown]; Region: COG3152
527001009185	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001009186	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
527001009187	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
527001009188	dimerization interface [polypeptide binding]; other site
527001009189	Pirin-related protein [General function prediction only]; Region: COG1741
527001009190	Pirin; Region: Pirin; pfam02678
527001009191	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
527001009192	potential frameshift: common BLAST hit: gi|194448867|ref|YP_002047276.1| inner membrane transport protein YhaO
527001009193	potential frameshift: common BLAST hit: gi|197251039|ref|YP_002148170.1| inner membrane transport protein YhaO
527001009194	L-serine dehydratase TdcG; Provisional; Region: PRK15040
527001009195	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
527001009196	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
527001009197	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
527001009198	Pyruvate formate lyase 1; Region: PFL1; cd01678
527001009199	coenzyme A binding site [chemical binding]; other site
527001009200	active site
527001009201	catalytic residues [active]
527001009202	glycine loop; other site
527001009203	propionate/acetate kinase; Provisional; Region: PRK12379
527001009204	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
527001009205	potential frameshift: common BLAST hit: gi|197249606|ref|YP_002148174.1| threonine/serine transporter TdcC
527001009206	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
527001009207	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
527001009208	tetramer interface [polypeptide binding]; other site
527001009209	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001009210	catalytic residue [active]
527001009211	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
527001009212	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001009213	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
527001009214	putative substrate binding pocket [chemical binding]; other site
527001009215	putative dimerization interface [polypeptide binding]; other site
527001009216	glycerate kinase I; Provisional; Region: PRK10342
527001009217	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
527001009218	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
527001009219	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
527001009220	galactarate dehydratase; Region: galactar-dH20; TIGR03248
527001009221	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
527001009222	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
527001009223	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
527001009224	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
527001009225	substrate binding site [chemical binding]; other site
527001009226	ATP binding site [chemical binding]; other site
527001009227	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
527001009228	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
527001009229	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001009230	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
527001009231	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
527001009232	intersubunit interface [polypeptide binding]; other site
527001009233	active site
527001009234	zinc binding site [ion binding]; other site
527001009235	Na+ binding site [ion binding]; other site
527001009236	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
527001009237	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
527001009238	putative substrate binding site [chemical binding]; other site
527001009239	putative ATP binding site [chemical binding]; other site
527001009240	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
527001009241	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
527001009242	active site
527001009243	P-loop; other site
527001009244	phosphorylation site [posttranslational modification]
527001009245	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
527001009246	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
527001009247	active site
527001009248	phosphorylation site [posttranslational modification]
527001009249	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
527001009250	dimerization domain swap beta strand [polypeptide binding]; other site
527001009251	regulatory protein interface [polypeptide binding]; other site
527001009252	active site
527001009253	regulatory phosphorylation site [posttranslational modification]; other site
527001009254	potential frameshift: common BLAST hit: gi|197364122|ref|YP_002143759.1| putative tagatose 6-phosphate kinase 1
527001009255	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
527001009256	active site
527001009257	phosphorylation site [posttranslational modification]
527001009258	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
527001009259	active site
527001009260	P-loop; other site
527001009261	phosphorylation site [posttranslational modification]
527001009262	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
527001009263	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
527001009264	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
527001009265	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
527001009266	putative NAD(P) binding site [chemical binding]; other site
527001009267	catalytic Zn binding site [ion binding]; other site
527001009268	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
527001009269	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
527001009270	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001009271	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
527001009272	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
527001009273	putative SAM binding site [chemical binding]; other site
527001009274	putative homodimer interface [polypeptide binding]; other site
527001009275	potential frameshift: common BLAST hit: gi|197364129|ref|YP_002143766.1| possible exported protein
527001009276	TIGR00252 family protein; Region: TIGR00252
527001009277	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
527001009278	dimer interface [polypeptide binding]; other site
527001009279	active site
527001009280	outer membrane lipoprotein; Provisional; Region: PRK11023
527001009281	BON domain; Region: BON; pfam04972
527001009282	BON domain; Region: BON; pfam04972
527001009283	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
527001009284	NADH(P)-binding; Region: NAD_binding_10; pfam13460
527001009285	NAD binding site [chemical binding]; other site
527001009286	active site
527001009287	intracellular protease, PfpI family; Region: PfpI; TIGR01382
527001009288	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
527001009289	proposed catalytic triad [active]
527001009290	conserved cys residue [active]
527001009291	hypothetical protein; Provisional; Region: PRK03467
527001009292	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
527001009293	GIY-YIG motif/motif A; other site
527001009294	putative active site [active]
527001009295	putative metal binding site [ion binding]; other site
527001009296	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
527001009297	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001009298	Coenzyme A binding pocket [chemical binding]; other site
527001009299	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
527001009300	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
527001009301	Peptidase family U32; Region: Peptidase_U32; pfam01136
527001009302	putative protease; Provisional; Region: PRK15447
527001009303	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
527001009304	hypothetical protein; Provisional; Region: PRK10508
527001009305	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
527001009306	tryptophan permease; Provisional; Region: PRK10483
527001009307	aromatic amino acid transport protein; Region: araaP; TIGR00837
527001009308	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
527001009309	DEAD-like helicases superfamily; Region: DEXDc; smart00487
527001009310	ATP binding site [chemical binding]; other site
527001009311	Mg++ binding site [ion binding]; other site
527001009312	motif III; other site
527001009313	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001009314	nucleotide binding region [chemical binding]; other site
527001009315	ATP-binding site [chemical binding]; other site
527001009316	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
527001009317	putative RNA binding site [nucleotide binding]; other site
527001009318	lipoprotein NlpI; Provisional; Region: PRK11189
527001009319	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
527001009320	binding surface
527001009321	TPR motif; other site
527001009322	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
527001009323	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
527001009324	RNase E interface [polypeptide binding]; other site
527001009325	trimer interface [polypeptide binding]; other site
527001009326	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
527001009327	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
527001009328	RNase E interface [polypeptide binding]; other site
527001009329	trimer interface [polypeptide binding]; other site
527001009330	active site
527001009331	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
527001009332	putative nucleic acid binding region [nucleotide binding]; other site
527001009333	G-X-X-G motif; other site
527001009334	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
527001009335	RNA binding site [nucleotide binding]; other site
527001009336	domain interface; other site
527001009337	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
527001009338	16S/18S rRNA binding site [nucleotide binding]; other site
527001009339	S13e-L30e interaction site [polypeptide binding]; other site
527001009340	25S rRNA binding site [nucleotide binding]; other site
527001009341	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
527001009342	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
527001009343	RNA binding site [nucleotide binding]; other site
527001009344	active site
527001009345	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
527001009346	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
527001009347	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
527001009348	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
527001009349	translation initiation factor IF-2; Region: IF-2; TIGR00487
527001009350	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
527001009351	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
527001009352	G1 box; other site
527001009353	putative GEF interaction site [polypeptide binding]; other site
527001009354	GTP/Mg2+ binding site [chemical binding]; other site
527001009355	Switch I region; other site
527001009356	G2 box; other site
527001009357	G3 box; other site
527001009358	Switch II region; other site
527001009359	G4 box; other site
527001009360	G5 box; other site
527001009361	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
527001009362	Translation-initiation factor 2; Region: IF-2; pfam11987
527001009363	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
527001009364	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
527001009365	NusA N-terminal domain; Region: NusA_N; pfam08529
527001009366	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
527001009367	RNA binding site [nucleotide binding]; other site
527001009368	homodimer interface [polypeptide binding]; other site
527001009369	NusA-like KH domain; Region: KH_5; pfam13184
527001009370	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
527001009371	G-X-X-G motif; other site
527001009372	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
527001009373	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
527001009374	ribosome maturation protein RimP; Reviewed; Region: PRK00092
527001009375	hypothetical protein; Provisional; Region: PRK14641
527001009376	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
527001009377	putative oligomer interface [polypeptide binding]; other site
527001009378	putative RNA binding site [nucleotide binding]; other site
527001009379	argininosuccinate synthase; Validated; Region: PRK05370
527001009380	argininosuccinate synthase; Provisional; Region: PRK13820
527001009381	Preprotein translocase SecG subunit; Region: SecG; pfam03840
527001009382	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
527001009383	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
527001009384	active site
527001009385	substrate binding site [chemical binding]; other site
527001009386	metal binding site [ion binding]; metal-binding site
527001009387	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
527001009388	dihydropteroate synthase; Region: DHPS; TIGR01496
527001009389	substrate binding pocket [chemical binding]; other site
527001009390	dimer interface [polypeptide binding]; other site
527001009391	inhibitor binding site; inhibition site
527001009392	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
527001009393	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001009394	Walker A motif; other site
527001009395	ATP binding site [chemical binding]; other site
527001009396	Walker B motif; other site
527001009397	arginine finger; other site
527001009398	Peptidase family M41; Region: Peptidase_M41; pfam01434
527001009399	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
527001009400	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001009401	S-adenosylmethionine binding site [chemical binding]; other site
527001009402	RNA-binding protein YhbY; Provisional; Region: PRK10343
527001009403	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
527001009404	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
527001009405	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
527001009406	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
527001009407	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
527001009408	GTPase CgtA; Reviewed; Region: obgE; PRK12298
527001009409	GTP1/OBG; Region: GTP1_OBG; pfam01018
527001009410	Obg GTPase; Region: Obg; cd01898
527001009411	G1 box; other site
527001009412	GTP/Mg2+ binding site [chemical binding]; other site
527001009413	Switch I region; other site
527001009414	G2 box; other site
527001009415	G3 box; other site
527001009416	Switch II region; other site
527001009417	G4 box; other site
527001009418	G5 box; other site
527001009419	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
527001009420	EamA-like transporter family; Region: EamA; pfam00892
527001009421	EamA-like transporter family; Region: EamA; pfam00892
527001009422	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
527001009423	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
527001009424	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
527001009425	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
527001009426	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
527001009427	substrate binding pocket [chemical binding]; other site
527001009428	chain length determination region; other site
527001009429	substrate-Mg2+ binding site; other site
527001009430	catalytic residues [active]
527001009431	aspartate-rich region 1; other site
527001009432	active site lid residues [active]
527001009433	aspartate-rich region 2; other site
527001009434	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
527001009435	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
527001009436	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
527001009437	hinge; other site
527001009438	active site
527001009439	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
527001009440	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
527001009441	anti sigma factor interaction site; other site
527001009442	regulatory phosphorylation site [posttranslational modification]; other site
527001009443	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
527001009444	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
527001009445	mce related protein; Region: MCE; pfam02470
527001009446	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
527001009447	conserved hypothetical integral membrane protein; Region: TIGR00056
527001009448	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
527001009449	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
527001009450	Walker A/P-loop; other site
527001009451	ATP binding site [chemical binding]; other site
527001009452	Q-loop/lid; other site
527001009453	ABC transporter signature motif; other site
527001009454	Walker B; other site
527001009455	D-loop; other site
527001009456	H-loop/switch region; other site
527001009457	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
527001009458	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
527001009459	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
527001009460	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
527001009461	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
527001009462	putative active site [active]
527001009463	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
527001009464	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
527001009465	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
527001009466	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
527001009467	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
527001009468	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
527001009469	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
527001009470	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
527001009471	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
527001009472	Walker A/P-loop; other site
527001009473	ATP binding site [chemical binding]; other site
527001009474	Q-loop/lid; other site
527001009475	ABC transporter signature motif; other site
527001009476	Walker B; other site
527001009477	D-loop; other site
527001009478	H-loop/switch region; other site
527001009479	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
527001009480	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
527001009481	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
527001009482	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
527001009483	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
527001009484	30S subunit binding site; other site
527001009485	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
527001009486	active site
527001009487	phosphorylation site [posttranslational modification]
527001009488	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
527001009489	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
527001009490	dimerization domain swap beta strand [polypeptide binding]; other site
527001009491	regulatory protein interface [polypeptide binding]; other site
527001009492	active site
527001009493	regulatory phosphorylation site [posttranslational modification]; other site
527001009494	hypothetical protein; Provisional; Region: PRK10345
527001009495	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
527001009496	Transglycosylase; Region: Transgly; cl17702
527001009497	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
527001009498	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
527001009499	conserved cys residue [active]
527001009500	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
527001009501	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
527001009502	putative active site [active]
527001009503	heme pocket [chemical binding]; other site
527001009504	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001009505	dimer interface [polypeptide binding]; other site
527001009506	phosphorylation site [posttranslational modification]
527001009507	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001009508	ATP binding site [chemical binding]; other site
527001009509	Mg2+ binding site [ion binding]; other site
527001009510	G-X-G motif; other site
527001009511	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001009512	active site
527001009513	phosphorylation site [posttranslational modification]
527001009514	intermolecular recognition site; other site
527001009515	dimerization interface [polypeptide binding]; other site
527001009516	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
527001009517	putative binding surface; other site
527001009518	active site
527001009519	radical SAM protein, TIGR01212 family; Region: TIGR01212
527001009520	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001009521	FeS/SAM binding site; other site
527001009522	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
527001009523	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
527001009524	active site
527001009525	dimer interface [polypeptide binding]; other site
527001009526	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
527001009527	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
527001009528	active site
527001009529	FMN binding site [chemical binding]; other site
527001009530	substrate binding site [chemical binding]; other site
527001009531	3Fe-4S cluster binding site [ion binding]; other site
527001009532	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
527001009533	domain interface; other site
527001009534	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
527001009535	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
527001009536	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001009537	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
527001009538	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
527001009539	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
527001009540	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
527001009541	Na binding site [ion binding]; other site
527001009542	putative substrate binding site [chemical binding]; other site
527001009543	cytosine deaminase; Provisional; Region: PRK09230
527001009544	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
527001009545	active site
527001009546	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
527001009547	N-acetylmannosamine kinase; Provisional; Region: PRK05082
527001009548	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
527001009549	nucleotide binding site [chemical binding]; other site
527001009550	Putative N-acetylmannosamine-6-phosphate epimerase; Region: NanE; pfam04131
527001009551	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
527001009552	putative sialic acid transporter; Provisional; Region: PRK03893
527001009553	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001009554	putative substrate translocation pore; other site
527001009555	N-acetylneuraminate lyase; Provisional; Region: PRK04147
527001009556	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
527001009557	inhibitor site; inhibition site
527001009558	active site
527001009559	dimer interface [polypeptide binding]; other site
527001009560	catalytic residue [active]
527001009561	transcriptional regulator NanR; Provisional; Region: PRK03837
527001009562	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001009563	DNA-binding site [nucleotide binding]; DNA binding site
527001009564	FCD domain; Region: FCD; pfam07729
527001009565	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
527001009566	stringent starvation protein A; Provisional; Region: sspA; PRK09481
527001009567	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
527001009568	C-terminal domain interface [polypeptide binding]; other site
527001009569	putative GSH binding site (G-site) [chemical binding]; other site
527001009570	dimer interface [polypeptide binding]; other site
527001009571	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
527001009572	dimer interface [polypeptide binding]; other site
527001009573	N-terminal domain interface [polypeptide binding]; other site
527001009574	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
527001009575	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
527001009576	23S rRNA interface [nucleotide binding]; other site
527001009577	L3 interface [polypeptide binding]; other site
527001009578	Predicted ATPase [General function prediction only]; Region: COG1485
527001009579	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
527001009580	hypothetical protein; Provisional; Region: PRK11677
527001009581	serine endoprotease; Provisional; Region: PRK10139
527001009582	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
527001009583	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
527001009584	protein binding site [polypeptide binding]; other site
527001009585	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
527001009586	serine endoprotease; Provisional; Region: PRK10898
527001009587	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
527001009588	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
527001009589	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
527001009590	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
527001009591	oxaloacetate decarboxylase; Provisional; Region: PRK14040
527001009592	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
527001009593	active site
527001009594	catalytic residues [active]
527001009595	metal binding site [ion binding]; metal-binding site
527001009596	homodimer binding site [polypeptide binding]; other site
527001009597	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
527001009598	carboxyltransferase (CT) interaction site; other site
527001009599	biotinylation site [posttranslational modification]; other site
527001009600	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
527001009601	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
527001009602	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
527001009603	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
527001009604	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
527001009605	transmembrane helices; other site
527001009606	Transcriptional regulators [Transcription]; Region: GntR; COG1802
527001009607	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001009608	DNA-binding site [nucleotide binding]; DNA binding site
527001009609	FCD domain; Region: FCD; pfam07729
527001009610	Transcriptional regulators [Transcription]; Region: GntR; COG1802
527001009611	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001009612	DNA-binding site [nucleotide binding]; DNA binding site
527001009613	malate dehydrogenase; Provisional; Region: PRK05086
527001009614	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
527001009615	NAD binding site [chemical binding]; other site
527001009616	dimerization interface [polypeptide binding]; other site
527001009617	Substrate binding site [chemical binding]; other site
527001009618	arginine repressor; Provisional; Region: PRK05066
527001009619	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
527001009620	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
527001009621	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
527001009622	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
527001009623	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
527001009624	RNAase interaction site [polypeptide binding]; other site
527001009625	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
527001009626	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
527001009627	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
527001009628	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
527001009629	HlyD family secretion protein; Region: HlyD_3; pfam13437
527001009630	efflux system membrane protein; Provisional; Region: PRK11594
527001009631	transcriptional regulator; Provisional; Region: PRK10632
527001009632	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001009633	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
527001009634	putative effector binding pocket; other site
527001009635	dimerization interface [polypeptide binding]; other site
527001009636	protease TldD; Provisional; Region: tldD; PRK10735
527001009637	hypothetical protein; Provisional; Region: PRK10899
527001009638	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
527001009639	ribonuclease G; Provisional; Region: PRK11712
527001009640	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
527001009641	homodimer interface [polypeptide binding]; other site
527001009642	oligonucleotide binding site [chemical binding]; other site
527001009643	Maf-like protein; Region: Maf; pfam02545
527001009644	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
527001009645	active site
527001009646	dimer interface [polypeptide binding]; other site
527001009647	rod shape-determining protein MreD; Provisional; Region: PRK11060
527001009648	rod shape-determining protein MreC; Region: mreC; TIGR00219
527001009649	rod shape-determining protein MreC; Region: MreC; pfam04085
527001009650	rod shape-determining protein MreB; Provisional; Region: PRK13927
527001009651	MreB and similar proteins; Region: MreB_like; cd10225
527001009652	nucleotide binding site [chemical binding]; other site
527001009653	Mg binding site [ion binding]; other site
527001009654	putative protofilament interaction site [polypeptide binding]; other site
527001009655	RodZ interaction site [polypeptide binding]; other site
527001009656	regulatory protein CsrD; Provisional; Region: PRK11059
527001009657	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001009658	metal binding site [ion binding]; metal-binding site
527001009659	active site
527001009660	I-site; other site
527001009661	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001009662	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
527001009663	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
527001009664	NADP binding site [chemical binding]; other site
527001009665	dimer interface [polypeptide binding]; other site
527001009666	TMAO/DMSO reductase; Reviewed; Region: PRK05363
527001009667	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
527001009668	Moco binding site; other site
527001009669	metal coordination site [ion binding]; other site
527001009670	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
527001009671	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
527001009672	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
527001009673	carboxyltransferase (CT) interaction site; other site
527001009674	biotinylation site [posttranslational modification]; other site
527001009675	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
527001009676	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
527001009677	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
527001009678	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
527001009679	hypothetical protein; Provisional; Region: PRK10633
527001009680	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
527001009681	Na binding site [ion binding]; other site
527001009682	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
527001009683	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
527001009684	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
527001009685	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
527001009686	FMN binding site [chemical binding]; other site
527001009687	active site
527001009688	catalytic residues [active]
527001009689	substrate binding site [chemical binding]; other site
527001009690	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
527001009691	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
527001009692	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
527001009693	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001009694	DNA methylase; Region: N6_N4_Mtase; pfam01555
527001009695	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
527001009696	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
527001009697	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
527001009698	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
527001009699	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001009700	metal binding site [ion binding]; metal-binding site
527001009701	active site
527001009702	I-site; other site
527001009703	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001009704	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
527001009705	potential frameshift: common BLAST hit: gi|197249559|ref|YP_002148316.1| AcrB protein
527001009706	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
527001009707	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
527001009708	potassium transporter; Provisional; Region: PRK10750
527001009709	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
527001009710	hypothetical protein; Provisional; Region: PRK11568
527001009711	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
527001009712	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
527001009713	proline dipeptidase; Provisional; Region: PRK13607
527001009714	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
527001009715	active site
527001009716	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
527001009717	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
527001009718	substrate binding site [chemical binding]; other site
527001009719	oxyanion hole (OAH) forming residues; other site
527001009720	trimer interface [polypeptide binding]; other site
527001009721	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
527001009722	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
527001009723	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
527001009724	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
527001009725	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
527001009726	dimer interface [polypeptide binding]; other site
527001009727	active site
527001009728	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
527001009729	FMN reductase; Validated; Region: fre; PRK08051
527001009730	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
527001009731	FAD binding pocket [chemical binding]; other site
527001009732	FAD binding motif [chemical binding]; other site
527001009733	phosphate binding motif [ion binding]; other site
527001009734	beta-alpha-beta structure motif; other site
527001009735	NAD binding pocket [chemical binding]; other site
527001009736	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
527001009737	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
527001009738	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
527001009739	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
527001009740	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
527001009741	active site
527001009742	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
527001009743	sec-independent translocase; Provisional; Region: PRK01770
527001009744	sec-independent translocase; Provisional; Region: tatB; PRK00404
527001009745	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
527001009746	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
527001009747	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
527001009748	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
527001009749	SCP-2 sterol transfer family; Region: SCP2; pfam02036
527001009750	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
527001009751	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001009752	S-adenosylmethionine binding site [chemical binding]; other site
527001009753	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
527001009754	DNA recombination protein RmuC; Provisional; Region: PRK10361
527001009755	RmuC family; Region: RmuC; pfam02646
527001009756	uridine phosphorylase; Provisional; Region: PRK11178
527001009757	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
527001009758	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
527001009759	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
527001009760	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001009761	FeS/SAM binding site; other site
527001009762	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
527001009763	SEC-C motif; Region: SEC-C; pfam02810
527001009764	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
527001009765	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
527001009766	THF binding site; other site
527001009767	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
527001009768	substrate binding site [chemical binding]; other site
527001009769	THF binding site; other site
527001009770	zinc-binding site [ion binding]; other site
527001009771	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
527001009772	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001009773	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
527001009774	putative dimerization interface [polypeptide binding]; other site
527001009775	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
527001009776	EamA-like transporter family; Region: EamA; pfam00892
527001009777	putative hydrolase; Provisional; Region: PRK10976
527001009778	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001009779	active site
527001009780	motif I; other site
527001009781	motif II; other site
527001009782	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001009783	lysophospholipase L2; Provisional; Region: PRK10749
527001009784	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
527001009785	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
527001009786	threonine efflux system; Provisional; Region: PRK10229
527001009787	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
527001009788	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001009789	ATP binding site [chemical binding]; other site
527001009790	putative Mg++ binding site [ion binding]; other site
527001009791	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001009792	nucleotide binding region [chemical binding]; other site
527001009793	ATP-binding site [chemical binding]; other site
527001009794	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
527001009795	Helicase and RNase D C-terminal; Region: HRDC; smart00341
527001009796	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
527001009797	dimerization interface [polypeptide binding]; other site
527001009798	substrate binding site [chemical binding]; other site
527001009799	active site
527001009800	calcium binding site [ion binding]; other site
527001009801	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
527001009802	CoenzymeA binding site [chemical binding]; other site
527001009803	subunit interaction site [polypeptide binding]; other site
527001009804	PHB binding site; other site
527001009805	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
527001009806	EamA-like transporter family; Region: EamA; cl17759
527001009807	hypothetical protein; Provisional; Region: PRK11371
527001009808	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
527001009809	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
527001009810	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
527001009811	Cl binding site [ion binding]; other site
527001009812	oligomer interface [polypeptide binding]; other site
527001009813	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
527001009814	Part of AAA domain; Region: AAA_19; pfam13245
527001009815	Family description; Region: UvrD_C_2; pfam13538
527001009816	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
527001009817	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001009818	motif II; other site
527001009819	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
527001009820	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
527001009821	active site
527001009822	Int/Topo IB signature motif; other site
527001009823	hypothetical protein; Provisional; Region: PRK10963
527001009824	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
527001009825	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
527001009826	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
527001009827	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
527001009828	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
527001009829	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
527001009830	putative iron binding site [ion binding]; other site
527001009831	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
527001009832	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
527001009833	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
527001009834	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
527001009835	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
527001009836	domain interfaces; other site
527001009837	active site
527001009838	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
527001009839	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
527001009840	active site
527001009841	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
527001009842	HemX; Region: HemX; pfam04375
527001009843	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
527001009844	HemY protein N-terminus; Region: HemY_N; pfam07219
527001009845	putative transport protein YifK; Provisional; Region: PRK10746
527001009846	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
527001009847	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
527001009848	putative common antigen polymerase; Provisional; Region: PRK02975
527001009849	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
527001009850	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
527001009851	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
527001009852	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
527001009853	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
527001009854	inhibitor-cofactor binding pocket; inhibition site
527001009855	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001009856	catalytic residue [active]
527001009857	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
527001009858	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
527001009859	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
527001009860	substrate binding site; other site
527001009861	tetramer interface; other site
527001009862	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
527001009863	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
527001009864	NAD binding site [chemical binding]; other site
527001009865	substrate binding site [chemical binding]; other site
527001009866	homodimer interface [polypeptide binding]; other site
527001009867	active site
527001009868	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
527001009869	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
527001009870	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
527001009871	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
527001009872	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
527001009873	homodimer interface [polypeptide binding]; other site
527001009874	active site
527001009875	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
527001009876	Chain length determinant protein; Region: Wzz; pfam02706
527001009877	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
527001009878	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
527001009879	Mg++ binding site [ion binding]; other site
527001009880	putative catalytic motif [active]
527001009881	substrate binding site [chemical binding]; other site
527001009882	transcription termination factor Rho; Provisional; Region: rho; PRK09376
527001009883	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
527001009884	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
527001009885	RNA binding site [nucleotide binding]; other site
527001009886	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
527001009887	multimer interface [polypeptide binding]; other site
527001009888	Walker A motif; other site
527001009889	ATP binding site [chemical binding]; other site
527001009890	Walker B motif; other site
527001009891	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
527001009892	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
527001009893	catalytic residues [active]
527001009894	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
527001009895	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
527001009896	ATP binding site [chemical binding]; other site
527001009897	Mg++ binding site [ion binding]; other site
527001009898	motif III; other site
527001009899	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001009900	nucleotide binding region [chemical binding]; other site
527001009901	ATP-binding site [chemical binding]; other site
527001009902	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
527001009903	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
527001009904	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
527001009905	Part of AAA domain; Region: AAA_19; pfam13245
527001009906	Family description; Region: UvrD_C_2; pfam13538
527001009907	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
527001009908	uridine phosphorylase; Provisional; Region: PRK11178
527001009909	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
527001009910	potential frameshift: common BLAST hit: gi|197248553|ref|YP_002148839.1| cyclic nucleotide-binding domain protein
527001009911	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
527001009912	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
527001009913	ketol-acid reductoisomerase; Validated; Region: PRK05225
527001009914	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
527001009915	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
527001009916	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
527001009917	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001009918	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
527001009919	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
527001009920	putative dimerization interface [polypeptide binding]; other site
527001009921	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
527001009922	Phage-related protein [Function unknown]; Region: COG4679
527001009923	threonine dehydratase; Reviewed; Region: PRK09224
527001009924	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
527001009925	tetramer interface [polypeptide binding]; other site
527001009926	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001009927	catalytic residue [active]
527001009928	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
527001009929	putative Ile/Val binding site [chemical binding]; other site
527001009930	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
527001009931	putative Ile/Val binding site [chemical binding]; other site
527001009932	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
527001009933	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
527001009934	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
527001009935	homodimer interface [polypeptide binding]; other site
527001009936	substrate-cofactor binding pocket; other site
527001009937	catalytic residue [active]
527001009938	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
527001009939	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
527001009940	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
527001009941	PYR/PP interface [polypeptide binding]; other site
527001009942	dimer interface [polypeptide binding]; other site
527001009943	TPP binding site [chemical binding]; other site
527001009944	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
527001009945	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
527001009946	TPP-binding site [chemical binding]; other site
527001009947	dimer interface [polypeptide binding]; other site
527001009948	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
527001009949	integrase; Provisional; Region: int; PHA02601
527001009950	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
527001009951	active site
527001009952	DNA binding site [nucleotide binding]
527001009953	Int/Topo IB signature motif; other site
527001009954	hypothetical protein; Provisional; Region: PRK10040
527001009955	Predicted transcriptional regulator [Transcription]; Region: COG2932
527001009956	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
527001009957	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
527001009958	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
527001009959	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
527001009960	DksA-like zinc finger domain containing protein; Region: PHA00080
527001009961	DNA adenine methylase (dam); Region: dam; TIGR00571
527001009962	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
527001009963	The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p; Region: HIRAN; smart00910
527001009964	portal vertex protein; Provisional; Region: Q; PHA02536
527001009965	Phage portal protein; Region: Phage_portal; pfam04860
527001009966	terminase ATPase subunit; Provisional; Region: P; PHA02535
527001009967	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
527001009968	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
527001009969	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
527001009970	capsid protein; Provisional; Region: N; PHA02538
527001009971	terminase endonuclease subunit; Provisional; Region: M; PHA02537
527001009972	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
527001009973	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
527001009974	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
527001009975	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
527001009976	catalytic residues [active]
527001009977	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
527001009978	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
527001009979	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
527001009980	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
527001009981	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
527001009982	baseplate wedge subunit; Provisional; Region: W; PHA02516
527001009983	baseplate assembly protein; Provisional; Region: J; PHA02568
527001009984	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
527001009985	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
527001009986	Phage Tail Collar Domain; Region: Collar; pfam07484
527001009987	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
527001009988	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
527001009989	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
527001009990	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
527001009991	catalytic residues [active]
527001009992	catalytic nucleophile [active]
527001009993	Presynaptic Site I dimer interface [polypeptide binding]; other site
527001009994	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
527001009995	Synaptic Flat tetramer interface [polypeptide binding]; other site
527001009996	Synaptic Site I dimer interface [polypeptide binding]; other site
527001009997	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
527001009998	DNA-binding interface [nucleotide binding]; DNA binding site
527001009999	major tail sheath protein; Provisional; Region: FI; PHA02560
527001010000	major tail tube protein; Provisional; Region: FII; PHA02600
527001010001	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
527001010002	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
527001010003	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
527001010004	Phage protein U [General function prediction only]; Region: COG3499
527001010005	tail protein; Provisional; Region: D; PHA02561
527001010006	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
527001010007	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
527001010008	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
527001010009	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001010010	Walker A motif; other site
527001010011	ATP binding site [chemical binding]; other site
527001010012	Walker B motif; other site
527001010013	arginine finger; other site
527001010014	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
527001010015	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001010016	hypothetical protein; Provisional; Region: PRK11027
527001010017	potential frameshift: common BLAST hit: gi|207859111|ref|YP_002245762.1| transcriptional regulator HdfR
527001010018	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
527001010019	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
527001010020	purine monophosphate binding site [chemical binding]; other site
527001010021	dimer interface [polypeptide binding]; other site
527001010022	putative catalytic residues [active]
527001010023	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
527001010024	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
527001010025	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
527001010026	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
527001010027	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
527001010028	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
527001010029	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001010030	active site
527001010031	phosphorylation site [posttranslational modification]
527001010032	intermolecular recognition site; other site
527001010033	dimerization interface [polypeptide binding]; other site
527001010034	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001010035	Walker A motif; other site
527001010036	ATP binding site [chemical binding]; other site
527001010037	Walker B motif; other site
527001010038	arginine finger; other site
527001010039	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
527001010040	potential frameshift: common BLAST hit: gi|29143772|ref|NP_807114.1| sensor protein ZraS
527001010041	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
527001010042	dimer interface [polypeptide binding]; other site
527001010043	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
527001010044	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
527001010045	IHF dimer interface [polypeptide binding]; other site
527001010046	IHF - DNA interface [nucleotide binding]; other site
527001010047	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
527001010048	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
527001010049	Active_site [active]
527001010050	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
527001010051	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
527001010052	substrate binding site [chemical binding]; other site
527001010053	active site
527001010054	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
527001010055	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
527001010056	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
527001010057	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
527001010058	putative NADH binding site [chemical binding]; other site
527001010059	putative active site [active]
527001010060	nudix motif; other site
527001010061	putative metal binding site [ion binding]; other site
527001010062	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
527001010063	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
527001010064	ThiC-associated domain; Region: ThiC-associated; pfam13667
527001010065	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
527001010066	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
527001010067	thiamine phosphate binding site [chemical binding]; other site
527001010068	active site
527001010069	pyrophosphate binding site [ion binding]; other site
527001010070	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
527001010071	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
527001010072	ATP binding site [chemical binding]; other site
527001010073	substrate interface [chemical binding]; other site
527001010074	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
527001010075	thiS-thiF/thiG interaction site; other site
527001010076	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
527001010077	ThiS interaction site; other site
527001010078	putative active site [active]
527001010079	tetramer interface [polypeptide binding]; other site
527001010080	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
527001010081	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001010082	FeS/SAM binding site; other site
527001010083	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
527001010084	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
527001010085	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
527001010086	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
527001010087	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
527001010088	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
527001010089	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
527001010090	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
527001010091	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
527001010092	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
527001010093	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
527001010094	DNA binding site [nucleotide binding]
527001010095	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
527001010096	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
527001010097	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
527001010098	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
527001010099	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
527001010100	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
527001010101	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
527001010102	RPB3 interaction site [polypeptide binding]; other site
527001010103	RPB1 interaction site [polypeptide binding]; other site
527001010104	RPB11 interaction site [polypeptide binding]; other site
527001010105	RPB10 interaction site [polypeptide binding]; other site
527001010106	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
527001010107	core dimer interface [polypeptide binding]; other site
527001010108	peripheral dimer interface [polypeptide binding]; other site
527001010109	L10 interface [polypeptide binding]; other site
527001010110	L11 interface [polypeptide binding]; other site
527001010111	putative EF-Tu interaction site [polypeptide binding]; other site
527001010112	putative EF-G interaction site [polypeptide binding]; other site
527001010113	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
527001010114	23S rRNA interface [nucleotide binding]; other site
527001010115	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
527001010116	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
527001010117	mRNA/rRNA interface [nucleotide binding]; other site
527001010118	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
527001010119	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
527001010120	23S rRNA interface [nucleotide binding]; other site
527001010121	L7/L12 interface [polypeptide binding]; other site
527001010122	putative thiostrepton binding site; other site
527001010123	L25 interface [polypeptide binding]; other site
527001010124	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
527001010125	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
527001010126	putative homodimer interface [polypeptide binding]; other site
527001010127	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
527001010128	heterodimer interface [polypeptide binding]; other site
527001010129	homodimer interface [polypeptide binding]; other site
527001010130	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
527001010131	elongation factor Tu; Reviewed; Region: PRK00049
527001010132	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
527001010133	G1 box; other site
527001010134	GEF interaction site [polypeptide binding]; other site
527001010135	GTP/Mg2+ binding site [chemical binding]; other site
527001010136	Switch I region; other site
527001010137	G2 box; other site
527001010138	G3 box; other site
527001010139	Switch II region; other site
527001010140	G4 box; other site
527001010141	G5 box; other site
527001010142	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
527001010143	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
527001010144	Antibiotic Binding Site [chemical binding]; other site
527001010145	potential protein location (hypothetical protein TY21A_17615 [Salmonella enterica subsp. enterica serovar Typhi str. Ty21]) that overlaps RNA (tRNA-T)
527001010146	potential protein location (hypothetical protein TY21A_17615 [Salmonella enterica subsp. enterica serovar Typhi str. Ty21]) that overlaps RNA (tRNA-Y)
527001010147	pantothenate kinase; Provisional; Region: PRK05439
527001010148	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
527001010149	ATP-binding site [chemical binding]; other site
527001010150	CoA-binding site [chemical binding]; other site
527001010151	Mg2+-binding site [ion binding]; other site
527001010152	Biotin operon repressor [Transcription]; Region: BirA; COG1654
527001010153	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
527001010154	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
527001010155	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
527001010156	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
527001010157	FAD binding domain; Region: FAD_binding_4; pfam01565
527001010158	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
527001010159	glutamate racemase; Provisional; Region: PRK00865
527001010160	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
527001010161	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
527001010162	N-terminal plug; other site
527001010163	ligand-binding site [chemical binding]; other site
527001010164	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
527001010165	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
527001010166	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001010167	S-adenosylmethionine binding site [chemical binding]; other site
527001010168	hypothetical protein; Provisional; Region: PRK11056
527001010169	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
527001010170	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001010171	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
527001010172	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001010173	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
527001010174	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
527001010175	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001010176	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
527001010177	dimerization interface [polypeptide binding]; other site
527001010178	argininosuccinate lyase; Provisional; Region: PRK04833
527001010179	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
527001010180	active sites [active]
527001010181	tetramer interface [polypeptide binding]; other site
527001010182	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
527001010183	nucleotide binding site [chemical binding]; other site
527001010184	N-acetyl-L-glutamate binding site [chemical binding]; other site
527001010185	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
527001010186	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
527001010187	acetylornithine deacetylase; Provisional; Region: PRK05111
527001010188	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
527001010189	metal binding site [ion binding]; metal-binding site
527001010190	putative dimer interface [polypeptide binding]; other site
527001010191	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
527001010192	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
527001010193	hypothetical protein; Provisional; Region: PRK10649
527001010194	Sulfatase; Region: Sulfatase; pfam00884
527001010195	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
527001010196	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001010197	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
527001010198	active site
527001010199	intersubunit interactions; other site
527001010200	catalytic residue [active]
527001010201	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
527001010202	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
527001010203	dimer interface [polypeptide binding]; other site
527001010204	active site
527001010205	metal binding site [ion binding]; metal-binding site
527001010206	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
527001010207	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
527001010208	heme binding site [chemical binding]; other site
527001010209	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
527001010210	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
527001010211	FAD binding site [chemical binding]; other site
527001010212	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
527001010213	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001010214	DNA-binding site [nucleotide binding]; DNA binding site
527001010215	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001010216	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001010217	homodimer interface [polypeptide binding]; other site
527001010218	catalytic residue [active]
527001010219	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
527001010220	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
527001010221	active site
527001010222	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
527001010223	dimer interface [polypeptide binding]; other site
527001010224	substrate binding site [chemical binding]; other site
527001010225	catalytic residues [active]
527001010226	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
527001010227	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
527001010228	dimer interface [polypeptide binding]; other site
527001010229	active site
527001010230	glycine-pyridoxal phosphate binding site [chemical binding]; other site
527001010231	folate binding site [chemical binding]; other site
527001010232	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
527001010233	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
527001010234	active site
527001010235	metal binding site [ion binding]; metal-binding site
527001010236	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
527001010237	aspartate aminotransferase; Provisional; Region: PRK06836
527001010238	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
527001010239	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
527001010240	putative catalytic residues [active]
527001010241	putative nucleotide binding site [chemical binding]; other site
527001010242	putative aspartate binding site [chemical binding]; other site
527001010243	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
527001010244	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
527001010245	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
527001010246	cystathionine gamma-synthase; Provisional; Region: PRK08045
527001010247	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
527001010248	homodimer interface [polypeptide binding]; other site
527001010249	substrate-cofactor binding pocket; other site
527001010250	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001010251	catalytic residue [active]
527001010252	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
527001010253	dimerization interface [polypeptide binding]; other site
527001010254	DNA binding site [nucleotide binding]
527001010255	corepressor binding sites; other site
527001010256	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
527001010257	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
527001010258	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
527001010259	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
527001010260	primosome assembly protein PriA; Validated; Region: PRK05580
527001010261	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001010262	ATP binding site [chemical binding]; other site
527001010263	putative Mg++ binding site [ion binding]; other site
527001010264	helicase superfamily c-terminal domain; Region: HELICc; smart00490
527001010265	ATP-binding site [chemical binding]; other site
527001010266	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001010267	DNA binding site [nucleotide binding]
527001010268	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
527001010269	domain linker motif; other site
527001010270	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
527001010271	dimerization interface [polypeptide binding]; other site
527001010272	ligand binding site [chemical binding]; other site
527001010273	Sporulation related domain; Region: SPOR; cl10051
527001010274	cell division protein FtsN; Provisional; Region: PRK12757
527001010275	Sporulation related domain; Region: SPOR; cl10051
527001010276	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
527001010277	active site
527001010278	HslU subunit interaction site [polypeptide binding]; other site
527001010279	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
527001010280	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001010281	Walker A motif; other site
527001010282	ATP binding site [chemical binding]; other site
527001010283	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
527001010284	Walker B motif; other site
527001010285	arginine finger; other site
527001010286	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
527001010287	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
527001010288	UbiA prenyltransferase family; Region: UbiA; pfam01040
527001010289	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
527001010290	septal ring assembly protein ZapB; Provisional; Region: PRK15422
527001010291	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
527001010292	amphipathic channel; other site
527001010293	Asn-Pro-Ala signature motifs; other site
527001010294	glycerol kinase; Provisional; Region: glpK; PRK00047
527001010295	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
527001010296	N- and C-terminal domain interface [polypeptide binding]; other site
527001010297	active site
527001010298	MgATP binding site [chemical binding]; other site
527001010299	catalytic site [active]
527001010300	metal binding site [ion binding]; metal-binding site
527001010301	glycerol binding site [chemical binding]; other site
527001010302	homotetramer interface [polypeptide binding]; other site
527001010303	homodimer interface [polypeptide binding]; other site
527001010304	FBP binding site [chemical binding]; other site
527001010305	protein IIAGlc interface [polypeptide binding]; other site
527001010306	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
527001010307	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
527001010308	putative active site [active]
527001010309	ferredoxin-NADP reductase; Provisional; Region: PRK10926
527001010310	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
527001010311	FAD binding pocket [chemical binding]; other site
527001010312	FAD binding motif [chemical binding]; other site
527001010313	phosphate binding motif [ion binding]; other site
527001010314	beta-alpha-beta structure motif; other site
527001010315	NAD binding pocket [chemical binding]; other site
527001010316	Predicted membrane protein [Function unknown]; Region: COG3152
527001010317	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
527001010318	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
527001010319	triosephosphate isomerase; Provisional; Region: PRK14567
527001010320	substrate binding site [chemical binding]; other site
527001010321	dimer interface [polypeptide binding]; other site
527001010322	catalytic triad [active]
527001010323	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
527001010324	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
527001010325	substrate binding site [chemical binding]; other site
527001010326	hexamer interface [polypeptide binding]; other site
527001010327	metal binding site [ion binding]; metal-binding site
527001010328	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
527001010329	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
527001010330	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
527001010331	putative active site; other site
527001010332	catalytic residue [active]
527001010333	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
527001010334	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
527001010335	ligand binding site [chemical binding]; other site
527001010336	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
527001010337	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
527001010338	TM-ABC transporter signature motif; other site
527001010339	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
527001010340	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
527001010341	TM-ABC transporter signature motif; other site
527001010342	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
527001010343	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
527001010344	Walker A/P-loop; other site
527001010345	ATP binding site [chemical binding]; other site
527001010346	Q-loop/lid; other site
527001010347	ABC transporter signature motif; other site
527001010348	Walker B; other site
527001010349	D-loop; other site
527001010350	H-loop/switch region; other site
527001010351	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
527001010352	transcriptional regulator LsrR; Provisional; Region: PRK15418
527001010353	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
527001010354	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
527001010355	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
527001010356	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
527001010357	putative N- and C-terminal domain interface [polypeptide binding]; other site
527001010358	putative active site [active]
527001010359	putative MgATP binding site [chemical binding]; other site
527001010360	catalytic site [active]
527001010361	metal binding site [ion binding]; metal-binding site
527001010362	putative carbohydrate binding site [chemical binding]; other site
527001010363	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
527001010364	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
527001010365	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
527001010366	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
527001010367	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001010368	DNA-binding site [nucleotide binding]; DNA binding site
527001010369	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
527001010370	UTRA domain; Region: UTRA; pfam07702
527001010371	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
527001010372	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
527001010373	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
527001010374	putative substrate binding site [chemical binding]; other site
527001010375	putative ATP binding site [chemical binding]; other site
527001010376	potential frameshift: common BLAST hit: gi|197248511|ref|YP_002148995.1| sugar (Glycoside-Pentoside-Hexuronide) transporter
527001010377	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
527001010378	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
527001010379	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001010380	substrate binding pocket [chemical binding]; other site
527001010381	membrane-bound complex binding site; other site
527001010382	hinge residues; other site
527001010383	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
527001010384	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
527001010385	active site
527001010386	ADP/pyrophosphate binding site [chemical binding]; other site
527001010387	dimerization interface [polypeptide binding]; other site
527001010388	allosteric effector site; other site
527001010389	fructose-1,6-bisphosphate binding site; other site
527001010390	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
527001010391	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
527001010392	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
527001010393	dimer interface [polypeptide binding]; other site
527001010394	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
527001010395	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001010396	active site
527001010397	intermolecular recognition site; other site
527001010398	dimerization interface [polypeptide binding]; other site
527001010399	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001010400	DNA binding site [nucleotide binding]
527001010401	two-component sensor protein; Provisional; Region: cpxA; PRK09470
527001010402	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001010403	dimerization interface [polypeptide binding]; other site
527001010404	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001010405	dimer interface [polypeptide binding]; other site
527001010406	phosphorylation site [posttranslational modification]
527001010407	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001010408	ATP binding site [chemical binding]; other site
527001010409	Mg2+ binding site [ion binding]; other site
527001010410	G-X-G motif; other site
527001010411	SnoaL-like domain; Region: SnoaL_2; pfam12680
527001010412	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
527001010413	MOSC domain; Region: MOSC; pfam03473
527001010414	3-alpha domain; Region: 3-alpha; pfam03475
527001010415	superoxide dismutase; Provisional; Region: PRK10925
527001010416	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
527001010417	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
527001010418	potential frameshift: common BLAST hit: gi|224585867|ref|YP_002639666.1| putative dicarboxylate-binding periplasmic protein
527001010419	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
527001010420	DctM-like transporters; Region: DctM; pfam06808
527001010421	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
527001010422	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
527001010423	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
527001010424	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
527001010425	transcriptional activator RhaR; Provisional; Region: PRK13502
527001010426	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
527001010427	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001010428	transcriptional activator RhaS; Provisional; Region: PRK13503
527001010429	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
527001010430	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001010431	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001010432	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
527001010433	N- and C-terminal domain interface [polypeptide binding]; other site
527001010434	active site
527001010435	putative catalytic site [active]
527001010436	metal binding site [ion binding]; metal-binding site
527001010437	ATP binding site [chemical binding]; other site
527001010438	rhamnulokinase; Provisional; Region: rhaB; PRK10640
527001010439	carbohydrate binding site [chemical binding]; other site
527001010440	L-rhamnose isomerase; Provisional; Region: PRK01076
527001010441	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
527001010442	potential frameshift: common BLAST hit: gi|197249656|ref|YP_002148973.1| rhamnulose-1-phosphate aldolase
527001010443	lactaldehyde reductase; Region: lactal_redase; TIGR02638
527001010444	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
527001010445	dimer interface [polypeptide binding]; other site
527001010446	active site
527001010447	metal binding site [ion binding]; metal-binding site
527001010448	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
527001010449	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
527001010450	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001010451	non-specific DNA binding site [nucleotide binding]; other site
527001010452	salt bridge; other site
527001010453	sequence-specific DNA binding site [nucleotide binding]; other site
527001010454	Cupin domain; Region: Cupin_2; cl17218
527001010455	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
527001010456	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
527001010457	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
527001010458	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
527001010459	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
527001010460	potential frameshift: common BLAST hit: gi|205354382|ref|YP_002228183.1| formate dehydrogenase-O, major subunit
527001010461	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
527001010462	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
527001010463	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
527001010464	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
527001010465	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
527001010466	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
527001010467	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
527001010468	oligomeric interface; other site
527001010469	putative active site [active]
527001010470	homodimer interface [polypeptide binding]; other site
527001010471	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
527001010472	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
527001010473	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
527001010474	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
527001010475	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001010476	non-specific DNA binding site [nucleotide binding]; other site
527001010477	salt bridge; other site
527001010478	sequence-specific DNA binding site [nucleotide binding]; other site
527001010479	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001010480	Coenzyme A binding pocket [chemical binding]; other site
527001010481	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
527001010482	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
527001010483	putative active site [active]
527001010484	dimerization interface [polypeptide binding]; other site
527001010485	putative tRNAtyr binding site [nucleotide binding]; other site
527001010486	hypothetical protein; Reviewed; Region: PRK01637
527001010487	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
527001010488	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001010489	motif II; other site
527001010490	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
527001010491	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
527001010492	putative DNA binding site [nucleotide binding]; other site
527001010493	putative Zn2+ binding site [ion binding]; other site
527001010494	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001010495	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
527001010496	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
527001010497	substrate binding site [chemical binding]; other site
527001010498	ATP binding site [chemical binding]; other site
527001010499	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
527001010500	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
527001010501	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
527001010502	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
527001010503	dimerization interface [polypeptide binding]; other site
527001010504	putative active cleft [active]
527001010505	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
527001010506	active site
527001010507	catalytic residues [active]
527001010508	alpha-glucosidase; Provisional; Region: PRK10426
527001010509	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
527001010510	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
527001010511	putative active site [active]
527001010512	putative catalytic site [active]
527001010513	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
527001010514	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
527001010515	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
527001010516	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001010517	putative substrate translocation pore; other site
527001010518	outer membrane porin L; Provisional; Region: ompL; PRK09980
527001010519	Sulfatase; Region: Sulfatase; cl17466
527001010520	potential frameshift: common BLAST hit: gi|197364787|ref|YP_002144424.1| coproporphyrinogen III oxidase
527001010521	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001010522	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
527001010523	active site
527001010524	motif I; other site
527001010525	motif II; other site
527001010526	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001010527	GTP-binding protein; Provisional; Region: PRK10218
527001010528	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
527001010529	G1 box; other site
527001010530	putative GEF interaction site [polypeptide binding]; other site
527001010531	GTP/Mg2+ binding site [chemical binding]; other site
527001010532	Switch I region; other site
527001010533	G2 box; other site
527001010534	G3 box; other site
527001010535	Switch II region; other site
527001010536	G4 box; other site
527001010537	G5 box; other site
527001010538	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
527001010539	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
527001010540	glutamine synthetase; Provisional; Region: glnA; PRK09469
527001010541	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
527001010542	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
527001010543	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
527001010544	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
527001010545	putative active site [active]
527001010546	heme pocket [chemical binding]; other site
527001010547	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001010548	dimer interface [polypeptide binding]; other site
527001010549	phosphorylation site [posttranslational modification]
527001010550	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001010551	ATP binding site [chemical binding]; other site
527001010552	Mg2+ binding site [ion binding]; other site
527001010553	G-X-G motif; other site
527001010554	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
527001010555	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001010556	active site
527001010557	phosphorylation site [posttranslational modification]
527001010558	intermolecular recognition site; other site
527001010559	dimerization interface [polypeptide binding]; other site
527001010560	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001010561	Walker A motif; other site
527001010562	ATP binding site [chemical binding]; other site
527001010563	Walker B motif; other site
527001010564	arginine finger; other site
527001010565	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
527001010566	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
527001010567	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001010568	FeS/SAM binding site; other site
527001010569	HemN C-terminal domain; Region: HemN_C; pfam06969
527001010570	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
527001010571	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
527001010572	G1 box; other site
527001010573	GTP/Mg2+ binding site [chemical binding]; other site
527001010574	Switch I region; other site
527001010575	G2 box; other site
527001010576	G3 box; other site
527001010577	Switch II region; other site
527001010578	G4 box; other site
527001010579	G5 box; other site
527001010580	DNA polymerase I; Provisional; Region: PRK05755
527001010581	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
527001010582	active site
527001010583	metal binding site 1 [ion binding]; metal-binding site
527001010584	putative 5' ssDNA interaction site; other site
527001010585	metal binding site 3; metal-binding site
527001010586	metal binding site 2 [ion binding]; metal-binding site
527001010587	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
527001010588	putative DNA binding site [nucleotide binding]; other site
527001010589	putative metal binding site [ion binding]; other site
527001010590	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
527001010591	active site
527001010592	catalytic site [active]
527001010593	substrate binding site [chemical binding]; other site
527001010594	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
527001010595	active site
527001010596	DNA binding site [nucleotide binding]
527001010597	catalytic site [active]
527001010598	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
527001010599	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
527001010600	putative acyl-acceptor binding pocket; other site
527001010601	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
527001010602	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
527001010603	catalytic residues [active]
527001010604	hinge region; other site
527001010605	alpha helical domain; other site
527001010606	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
527001010607	serine/threonine protein kinase; Provisional; Region: PRK11768
527001010608	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
527001010609	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
527001010610	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
527001010611	GTP binding site; other site
527001010612	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
527001010613	Walker A motif; other site
527001010614	Transcriptional regulators [Transcription]; Region: FadR; COG2186
527001010615	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001010616	DNA-binding site [nucleotide binding]; DNA binding site
527001010617	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
527001010618	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001010619	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001010620	transcriptional repressor RbsR; Provisional; Region: PRK10423
527001010621	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001010622	DNA binding site [nucleotide binding]
527001010623	domain linker motif; other site
527001010624	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
527001010625	dimerization interface [polypeptide binding]; other site
527001010626	ligand binding site [chemical binding]; other site
527001010627	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
527001010628	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
527001010629	substrate binding site [chemical binding]; other site
527001010630	dimer interface [polypeptide binding]; other site
527001010631	ATP binding site [chemical binding]; other site
527001010632	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
527001010633	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
527001010634	ligand binding site [chemical binding]; other site
527001010635	dimerization interface [polypeptide binding]; other site
527001010636	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
527001010637	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
527001010638	TM-ABC transporter signature motif; other site
527001010639	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
527001010640	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
527001010641	Walker A/P-loop; other site
527001010642	ATP binding site [chemical binding]; other site
527001010643	Q-loop/lid; other site
527001010644	ABC transporter signature motif; other site
527001010645	Walker B; other site
527001010646	D-loop; other site
527001010647	H-loop/switch region; other site
527001010648	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
527001010649	D-ribose pyranase; Provisional; Region: PRK11797
527001010650	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
527001010651	potassium uptake protein; Region: kup; TIGR00794
527001010652	regulatory ATPase RavA; Provisional; Region: PRK13531
527001010653	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001010654	Walker A motif; other site
527001010655	ATP binding site [chemical binding]; other site
527001010656	Walker B motif; other site
527001010657	arginine finger; other site
527001010658	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
527001010659	hypothetical protein; Provisional; Region: yieM; PRK10997
527001010660	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
527001010661	metal ion-dependent adhesion site (MIDAS); other site
527001010662	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
527001010663	motif 3; other site
527001010664	Asparagine synthetase A [Amino acid transport and metabolism]; Region: AsnA; COG2502
527001010665	motif 1; other site
527001010666	dimer interface [polypeptide binding]; other site
527001010667	active site
527001010668	motif 2; other site
527001010669	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
527001010670	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
527001010671	putative DNA binding site [nucleotide binding]; other site
527001010672	putative Zn2+ binding site [ion binding]; other site
527001010673	AsnC family; Region: AsnC_trans_reg; pfam01037
527001010674	FMN-binding protein MioC; Provisional; Region: PRK09004
527001010675	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
527001010676	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
527001010677	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
527001010678	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
527001010679	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001010680	S-adenosylmethionine binding site [chemical binding]; other site
527001010681	ATP synthase I chain; Region: ATP_synt_I; cl09170
527001010682	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
527001010683	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
527001010684	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
527001010685	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
527001010686	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
527001010687	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
527001010688	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
527001010689	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
527001010690	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
527001010691	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
527001010692	beta subunit interaction interface [polypeptide binding]; other site
527001010693	Walker A motif; other site
527001010694	ATP binding site [chemical binding]; other site
527001010695	Walker B motif; other site
527001010696	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
527001010697	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
527001010698	core domain interface [polypeptide binding]; other site
527001010699	delta subunit interface [polypeptide binding]; other site
527001010700	epsilon subunit interface [polypeptide binding]; other site
527001010701	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
527001010702	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
527001010703	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
527001010704	alpha subunit interaction interface [polypeptide binding]; other site
527001010705	Walker A motif; other site
527001010706	ATP binding site [chemical binding]; other site
527001010707	Walker B motif; other site
527001010708	inhibitor binding site; inhibition site
527001010709	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
527001010710	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
527001010711	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
527001010712	gamma subunit interface [polypeptide binding]; other site
527001010713	epsilon subunit interface [polypeptide binding]; other site
527001010714	LBP interface [polypeptide binding]; other site
527001010715	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
527001010716	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
527001010717	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
527001010718	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
527001010719	Substrate binding site; other site
527001010720	Mg++ binding site; other site
527001010721	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
527001010722	active site
527001010723	substrate binding site [chemical binding]; other site
527001010724	CoA binding site [chemical binding]; other site
527001010725	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
527001010726	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
527001010727	glutaminase active site [active]
527001010728	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
527001010729	dimer interface [polypeptide binding]; other site
527001010730	active site
527001010731	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
527001010732	dimer interface [polypeptide binding]; other site
527001010733	active site
527001010734	fimbrial protein; Provisional; Region: lpfA; PRK15289
527001010735	fimbrial chaperone protein; Provisional; Region: lfpB; PRK15290
527001010736	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001010737	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001010738	potential frameshift: common BLAST hit: gi|254795730|ref|YP_003080567.1| fimbrial usher
527001010739	fimbrial protein StgD; Provisional; Region: PRK15291
527001010740	potential frameshift: common BLAST hit: gi|194446062|ref|YP_002043106.1| HTH-type transcriptional regulator SgrR
527001010741	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
527001010742	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
527001010743	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
527001010744	shikimate binding site; other site
527001010745	NAD(P) binding site [chemical binding]; other site
527001010746	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
527001010747	active site
527001010748	P-loop; other site
527001010749	phosphorylation site [posttranslational modification]
527001010750	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
527001010751	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
527001010752	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001010753	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
527001010754	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001010755	dimer interface [polypeptide binding]; other site
527001010756	conserved gate region; other site
527001010757	putative PBP binding loops; other site
527001010758	ABC-ATPase subunit interface; other site
527001010759	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
527001010760	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001010761	dimer interface [polypeptide binding]; other site
527001010762	conserved gate region; other site
527001010763	putative PBP binding loops; other site
527001010764	ABC-ATPase subunit interface; other site
527001010765	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
527001010766	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
527001010767	Walker A/P-loop; other site
527001010768	ATP binding site [chemical binding]; other site
527001010769	Q-loop/lid; other site
527001010770	ABC transporter signature motif; other site
527001010771	Walker B; other site
527001010772	D-loop; other site
527001010773	H-loop/switch region; other site
527001010774	transcriptional regulator PhoU; Provisional; Region: PRK11115
527001010775	PhoU domain; Region: PhoU; pfam01895
527001010776	PhoU domain; Region: PhoU; pfam01895
527001010777	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
527001010778	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001010779	active site
527001010780	motif I; other site
527001010781	motif II; other site
527001010782	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
527001010783	Predicted flavoprotein [General function prediction only]; Region: COG0431
527001010784	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
527001010785	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
527001010786	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
527001010787	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001010788	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
527001010789	substrate binding pocket [chemical binding]; other site
527001010790	dimerization interface [polypeptide binding]; other site
527001010791	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
527001010792	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001010793	putative substrate translocation pore; other site
527001010794	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
527001010795	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
527001010796	trmE is a tRNA modification GTPase; Region: trmE; cd04164
527001010797	G1 box; other site
527001010798	GTP/Mg2+ binding site [chemical binding]; other site
527001010799	Switch I region; other site
527001010800	G2 box; other site
527001010801	Switch II region; other site
527001010802	G3 box; other site
527001010803	G4 box; other site
527001010804	G5 box; other site
527001010805	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
527001010806	membrane protein insertase; Provisional; Region: PRK01318
527001010807	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
527001010808	hypothetical protein; Validated; Region: PRK00041
527001010809	ribonuclease P; Reviewed; Region: rnpA; PRK01732
527001010810	DnaA N-terminal domain; Region: DnaA_N; pfam11638
527001010811	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
527001010812	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001010813	Walker A motif; other site
527001010814	ATP binding site [chemical binding]; other site
527001010815	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
527001010816	Walker B motif; other site
527001010817	arginine finger; other site
527001010818	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
527001010819	DnaA box-binding interface [nucleotide binding]; other site
527001010820	DNA polymerase III subunit beta; Validated; Region: PRK05643
527001010821	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
527001010822	putative DNA binding surface [nucleotide binding]; other site
527001010823	dimer interface [polypeptide binding]; other site
527001010824	beta-clamp/clamp loader binding surface; other site
527001010825	beta-clamp/translesion DNA polymerase binding surface; other site
527001010826	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
527001010827	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001010828	Mg2+ binding site [ion binding]; other site
527001010829	G-X-G motif; other site
527001010830	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
527001010831	anchoring element; other site
527001010832	dimer interface [polypeptide binding]; other site
527001010833	ATP binding site [chemical binding]; other site
527001010834	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
527001010835	active site
527001010836	putative metal-binding site [ion binding]; other site
527001010837	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
527001010838	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001010839	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001010840	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
527001010841	putative dimerization interface [polypeptide binding]; other site
527001010842	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
527001010843	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
527001010844	active site pocket [active]
527001010845	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001010846	D-galactonate transporter; Region: 2A0114; TIGR00893
527001010847	putative substrate translocation pore; other site
527001010848	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001010849	sugar phosphate phosphatase; Provisional; Region: PRK10513
527001010850	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001010851	active site
527001010852	motif I; other site
527001010853	motif II; other site
527001010854	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001010855	Surface antigen; Region: Bac_surface_Ag; pfam01103
527001010856	Protein of unknown function (DUF4056); Region: DUF4056; pfam13265
527001010857	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
527001010858	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001010859	dimer interface [polypeptide binding]; other site
527001010860	phosphorylation site [posttranslational modification]
527001010861	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001010862	ATP binding site [chemical binding]; other site
527001010863	Mg2+ binding site [ion binding]; other site
527001010864	G-X-G motif; other site
527001010865	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001010866	active site
527001010867	phosphorylation site [posttranslational modification]
527001010868	intermolecular recognition site; other site
527001010869	dimerization interface [polypeptide binding]; other site
527001010870	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
527001010871	putative binding surface; other site
527001010872	active site
527001010873	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
527001010874	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
527001010875	potential frameshift: common BLAST hit: gi|198245190|ref|YP_002217773.1| DNA-binding transcriptional regulator TorR
527001010876	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
527001010877	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
527001010878	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
527001010879	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
527001010880	molybdopterin cofactor binding site [chemical binding]; other site
527001010881	substrate binding site [chemical binding]; other site
527001010882	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
527001010883	molybdopterin cofactor binding site; other site
527001010884	chaperone protein TorD; Validated; Region: torD; PRK04976
527001010885	Haem-binding domain; Region: Haem_bd; pfam14376
527001010886	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
527001010887	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
527001010888	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001010889	Walker A/P-loop; other site
527001010890	ATP binding site [chemical binding]; other site
527001010891	Q-loop/lid; other site
527001010892	ABC transporter signature motif; other site
527001010893	Walker B; other site
527001010894	D-loop; other site
527001010895	H-loop/switch region; other site
527001010896	heme exporter protein CcmB; Region: ccmB; TIGR01190
527001010897	heme exporter protein CcmC; Region: ccmC; TIGR01191
527001010898	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
527001010899	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
527001010900	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
527001010901	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
527001010902	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
527001010903	catalytic residues [active]
527001010904	central insert; other site
527001010905	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
527001010906	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
527001010907	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
527001010908	hypothetical protein; Provisional; Region: PRK11616
527001010909	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
527001010910	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
527001010911	putative dimer interface [polypeptide binding]; other site
527001010912	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
527001010913	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
527001010914	putative dimer interface [polypeptide binding]; other site
527001010915	putative transporter; Validated; Region: PRK03818
527001010916	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
527001010917	TrkA-C domain; Region: TrkA_C; pfam02080
527001010918	TrkA-C domain; Region: TrkA_C; pfam02080
527001010919	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
527001010920	Domain of unknown function (DUF202); Region: DUF202; cl09954
527001010921	Domain of unknown function (DUF202); Region: DUF202; cl09954
527001010922	Domain of unknown function (DUF202); Region: DUF202; pfam02656
527001010923	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
527001010924	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
527001010925	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
527001010926	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
527001010927	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
527001010928	catalytic residue [active]
527001010929	permease DsdX; Provisional; Region: PRK09921
527001010930	gluconate transporter; Region: gntP; TIGR00791
527001010931	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
527001010932	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001010933	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
527001010934	dimerization interface [polypeptide binding]; other site
527001010935	substrate binding pocket [chemical binding]; other site
527001010936	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
527001010937	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001010938	putative substrate translocation pore; other site
527001010939	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
527001010940	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
527001010941	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
527001010942	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
527001010943	PYR/PP interface [polypeptide binding]; other site
527001010944	dimer interface [polypeptide binding]; other site
527001010945	TPP binding site [chemical binding]; other site
527001010946	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
527001010947	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
527001010948	TPP-binding site [chemical binding]; other site
527001010949	dimer interface [polypeptide binding]; other site
527001010950	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
527001010951	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
527001010952	putative valine binding site [chemical binding]; other site
527001010953	dimer interface [polypeptide binding]; other site
527001010954	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
527001010955	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
527001010956	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001010957	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
527001010958	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
527001010959	substrate binding site [chemical binding]; other site
527001010960	dimer interface [polypeptide binding]; other site
527001010961	ATP binding site [chemical binding]; other site
527001010962	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
527001010963	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001010964	putative substrate translocation pore; other site
527001010965	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
527001010966	active site
527001010967	catalytic residues [active]
527001010968	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
527001010969	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001010970	active site
527001010971	phosphorylation site [posttranslational modification]
527001010972	intermolecular recognition site; other site
527001010973	dimerization interface [polypeptide binding]; other site
527001010974	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001010975	DNA binding residues [nucleotide binding]
527001010976	dimerization interface [polypeptide binding]; other site
527001010977	sensory histidine kinase UhpB; Provisional; Region: PRK11644
527001010978	MASE1; Region: MASE1; pfam05231
527001010979	Histidine kinase; Region: HisKA_3; pfam07730
527001010980	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001010981	ATP binding site [chemical binding]; other site
527001010982	Mg2+ binding site [ion binding]; other site
527001010983	G-X-G motif; other site
527001010984	regulatory protein UhpC; Provisional; Region: PRK11663
527001010985	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001010986	putative substrate translocation pore; other site
527001010987	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
527001010988	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001010989	putative substrate translocation pore; other site
527001010990	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
527001010991	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
527001010992	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001010993	DNA-binding site [nucleotide binding]; DNA binding site
527001010994	UTRA domain; Region: UTRA; pfam07702
527001010995	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
527001010996	active site
527001010997	phosphorylation site [posttranslational modification]
527001010998	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
527001010999	active site
527001011000	P-loop; other site
527001011001	phosphorylation site [posttranslational modification]
527001011002	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
527001011003	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
527001011004	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
527001011005	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
527001011006	putative N- and C-terminal domain interface [polypeptide binding]; other site
527001011007	putative active site [active]
527001011008	putative MgATP binding site [chemical binding]; other site
527001011009	catalytic site [active]
527001011010	metal binding site [ion binding]; metal-binding site
527001011011	putative carbohydrate binding site [chemical binding]; other site
527001011012	potential frameshift: common BLAST hit: gi|197364591|ref|YP_002144228.1| putative fructose-1,6-bisphosphate aldolase
527001011013	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
527001011014	dimerization domain swap beta strand [polypeptide binding]; other site
527001011015	regulatory protein interface [polypeptide binding]; other site
527001011016	active site
527001011017	regulatory phosphorylation site [posttranslational modification]; other site
527001011018	Predicted transcriptional regulator [Transcription]; Region: COG2944
527001011019	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001011020	non-specific DNA binding site [nucleotide binding]; other site
527001011021	salt bridge; other site
527001011022	sequence-specific DNA binding site [nucleotide binding]; other site
527001011023	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
527001011024	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
527001011025	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
527001011026	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001011027	putative substrate translocation pore; other site
527001011028	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
527001011029	beta-galactosidase; Region: BGL; TIGR03356
527001011030	HTH domain; Region: HTH_11; cl17392
527001011031	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001011032	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
527001011033	Walker A motif; other site
527001011034	ATP binding site [chemical binding]; other site
527001011035	Walker B motif; other site
527001011036	arginine finger; other site
527001011037	Transcriptional antiterminator [Transcription]; Region: COG3933
527001011038	PRD domain; Region: PRD; pfam00874
527001011039	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
527001011040	active pocket/dimerization site; other site
527001011041	active site
527001011042	phosphorylation site [posttranslational modification]
527001011043	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
527001011044	active site
527001011045	phosphorylation site [posttranslational modification]
527001011046	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
527001011047	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
527001011048	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
527001011049	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
527001011050	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
527001011051	hypothetical protein; Provisional; Region: PRK09956
527001011052	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
527001011053	EamA-like transporter family; Region: EamA; pfam00892
527001011054	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
527001011055	EamA-like transporter family; Region: EamA; pfam00892
527001011056	magnesium transport protein MgtC; Provisional; Region: PRK15385
527001011057	MgtC family; Region: MgtC; pfam02308
527001011058	magnesium-transporting ATPase; Provisional; Region: PRK15122
527001011059	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
527001011060	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
527001011061	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
527001011062	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
527001011063	Soluble P-type ATPase [General function prediction only]; Region: COG4087
527001011064	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
527001011065	Isochorismatase family; Region: Isochorismatase; pfam00857
527001011066	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
527001011067	catalytic triad [active]
527001011068	dimer interface [polypeptide binding]; other site
527001011069	conserved cis-peptide bond; other site
527001011070	potential frameshift: common BLAST hit: gi|197364572|ref|YP_002144209.1| putative transcriptional regulatory protein
527001011071	potential frameshift: common BLAST hit: gi|197247791|ref|YP_002148692.1| outer membrane autotransporter barrel domain
527001011072	Transposase; Region: HTH_Tnp_1; cl17663
527001011073	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
527001011074	Transposase; Region: HTH_Tnp_1; pfam01527
527001011075	Virulence protein [General function prediction only]; Region: COG3943
527001011076	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
527001011077	TIGR02646 family protein; Region: TIGR02646
527001011078	putative transporter; Provisional; Region: PRK11462
527001011079	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
527001011080	putative alpha-glucosidase; Provisional; Region: PRK10658
527001011081	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
527001011082	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
527001011083	active site
527001011084	homotrimer interface [polypeptide binding]; other site
527001011085	catalytic site [active]
527001011086	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
527001011087	AsmA family; Region: AsmA; pfam05170
527001011088	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
527001011089	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
527001011090	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
527001011091	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
527001011092	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
527001011093	generic binding surface II; other site
527001011094	ssDNA binding site; other site
527001011095	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001011096	ATP binding site [chemical binding]; other site
527001011097	putative Mg++ binding site [ion binding]; other site
527001011098	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001011099	nucleotide binding region [chemical binding]; other site
527001011100	ATP-binding site [chemical binding]; other site
527001011101	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
527001011102	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
527001011103	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
527001011104	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
527001011105	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
527001011106	Zn2+ binding site [ion binding]; other site
527001011107	Mg2+ binding site [ion binding]; other site
527001011108	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
527001011109	synthetase active site [active]
527001011110	NTP binding site [chemical binding]; other site
527001011111	metal binding site [ion binding]; metal-binding site
527001011112	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
527001011113	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
527001011114	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
527001011115	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
527001011116	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
527001011117	catalytic site [active]
527001011118	G-X2-G-X-G-K; other site
527001011119	potential frameshift: common BLAST hit: gi|197364556|ref|YP_002144193.1| NAD-dependent DNA ligase LigB
527001011120	Predicted membrane protein [Function unknown]; Region: COG2860
527001011121	UPF0126 domain; Region: UPF0126; pfam03458
527001011122	UPF0126 domain; Region: UPF0126; pfam03458
527001011123	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
527001011124	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001011125	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001011126	dimerization interface [polypeptide binding]; other site
527001011127	LysR substrate binding domain; Region: LysR_substrate; pfam03466
527001011128	hypothetical protein; Provisional; Region: PRK11820
527001011129	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
527001011130	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
527001011131	ribonuclease PH; Reviewed; Region: rph; PRK00173
527001011132	Ribonuclease PH; Region: RNase_PH_bact; cd11362
527001011133	hexamer interface [polypeptide binding]; other site
527001011134	active site
527001011135	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
527001011136	active site
527001011137	division inhibitor protein; Provisional; Region: slmA; PRK09480
527001011138	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001011139	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
527001011140	trimer interface [polypeptide binding]; other site
527001011141	active site
527001011142	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
527001011143	Flavoprotein; Region: Flavoprotein; pfam02441
527001011144	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
527001011145	hypothetical protein; Reviewed; Region: PRK00024
527001011146	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
527001011147	MPN+ (JAMM) motif; other site
527001011148	Zinc-binding site [ion binding]; other site
527001011149	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
527001011150	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
527001011151	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
527001011152	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
527001011153	DNA binding site [nucleotide binding]
527001011154	catalytic residue [active]
527001011155	H2TH interface [polypeptide binding]; other site
527001011156	putative catalytic residues [active]
527001011157	turnover-facilitating residue; other site
527001011158	intercalation triad [nucleotide binding]; other site
527001011159	8OG recognition residue [nucleotide binding]; other site
527001011160	putative reading head residues; other site
527001011161	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
527001011162	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
527001011163	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
527001011164	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
527001011165	active site
527001011166	(T/H)XGH motif; other site
527001011167	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
527001011168	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
527001011169	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
527001011170	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
527001011171	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
527001011172	putative active site [active]
527001011173	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
527001011174	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
527001011175	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
527001011176	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
527001011177	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
527001011178	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
527001011179	putative ADP-binding pocket [chemical binding]; other site
527001011180	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
527001011181	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
527001011182	Ligand binding site; other site
527001011183	metal-binding site
527001011184	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
527001011185	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
527001011186	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
527001011187	Ligand binding site; other site
527001011188	metal-binding site
527001011189	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
527001011190	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
527001011191	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
527001011192	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
527001011193	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
527001011194	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
527001011195	O-antigen ligase RfaL; Provisional; Region: PRK15487
527001011196	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
527001011197	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
527001011198	putative active site [active]
527001011199	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
527001011200	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
527001011201	putative active site [active]
527001011202	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
527001011203	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
527001011204	NADP binding site [chemical binding]; other site
527001011205	homopentamer interface [polypeptide binding]; other site
527001011206	substrate binding site [chemical binding]; other site
527001011207	active site
527001011208	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
527001011209	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
527001011210	substrate-cofactor binding pocket; other site
527001011211	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001011212	catalytic residue [active]
527001011213	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
527001011214	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
527001011215	NAD(P) binding site [chemical binding]; other site
527001011216	putative glycosyl transferase; Provisional; Region: PRK10073
527001011217	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
527001011218	active site
527001011219	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
527001011220	NodB motif; other site
527001011221	putative active site [active]
527001011222	putative catalytic site [active]
527001011223	Zn binding site [ion binding]; other site
527001011224	AmiB activator; Provisional; Region: PRK11637
527001011225	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
527001011226	Peptidase family M23; Region: Peptidase_M23; pfam01551
527001011227	phosphoglyceromutase; Provisional; Region: PRK05434
527001011228	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
527001011229	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
527001011230	active site residue [active]
527001011231	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
527001011232	GSH binding site [chemical binding]; other site
527001011233	catalytic residues [active]
527001011234	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
527001011235	SecA binding site; other site
527001011236	Preprotein binding site; other site
527001011237	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
527001011238	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
527001011239	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
527001011240	serine acetyltransferase; Provisional; Region: cysE; PRK11132
527001011241	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
527001011242	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
527001011243	trimer interface [polypeptide binding]; other site
527001011244	active site
527001011245	substrate binding site [chemical binding]; other site
527001011246	CoA binding site [chemical binding]; other site
527001011247	potential frameshift: common BLAST hit: gi|197247731|ref|YP_002148631.1| probable glucarate transporter
527001011248	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
527001011249	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
527001011250	active site pocket [active]
527001011251	Transcriptional regulators [Transcription]; Region: PurR; COG1609
527001011252	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001011253	DNA binding site [nucleotide binding]
527001011254	domain linker motif; other site
527001011255	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
527001011256	putative dimerization interface [polypeptide binding]; other site
527001011257	putative ligand binding site [chemical binding]; other site
527001011258	putative rRNA methylase; Provisional; Region: PRK10358
527001011259	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
527001011260	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
527001011261	active site
527001011262	substrate binding site [chemical binding]; other site
527001011263	FMN binding site [chemical binding]; other site
527001011264	putative catalytic residues [active]
527001011265	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
527001011266	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001011267	DNA-binding site [nucleotide binding]; DNA binding site
527001011268	FCD domain; Region: FCD; pfam07729
527001011269	L-lactate permease; Provisional; Region: PRK10420
527001011270	glycolate transporter; Provisional; Region: PRK09695
527001011271	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
527001011272	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
527001011273	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
527001011274	Haemagglutinin; Region: HIM; pfam05662
527001011275	Haemagglutinin; Region: HIM; pfam05662
527001011276	YadA-like C-terminal region; Region: YadA; pfam03895
527001011277	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
527001011278	hypothetical protein; Provisional; Region: PRK11020
527001011279	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
527001011280	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
527001011281	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
527001011282	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
527001011283	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
527001011284	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
527001011285	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
527001011286	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
527001011287	active site
527001011288	P-loop; other site
527001011289	phosphorylation site [posttranslational modification]
527001011290	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
527001011291	active site
527001011292	phosphorylation site [posttranslational modification]
527001011293	putative glutathione S-transferase; Provisional; Region: PRK10357
527001011294	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
527001011295	putative C-terminal domain interface [polypeptide binding]; other site
527001011296	putative GSH binding site (G-site) [chemical binding]; other site
527001011297	putative dimer interface [polypeptide binding]; other site
527001011298	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
527001011299	dimer interface [polypeptide binding]; other site
527001011300	N-terminal domain interface [polypeptide binding]; other site
527001011301	putative substrate binding pocket (H-site) [chemical binding]; other site
527001011302	selenocysteine synthase; Provisional; Region: PRK04311
527001011303	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
527001011304	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
527001011305	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
527001011306	catalytic residue [active]
527001011307	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
527001011308	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
527001011309	G1 box; other site
527001011310	putative GEF interaction site [polypeptide binding]; other site
527001011311	GTP/Mg2+ binding site [chemical binding]; other site
527001011312	Switch I region; other site
527001011313	G2 box; other site
527001011314	G3 box; other site
527001011315	Switch II region; other site
527001011316	G4 box; other site
527001011317	G5 box; other site
527001011318	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
527001011319	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
527001011320	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
527001011321	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
527001011322	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
527001011323	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
527001011324	nucleotide binding site [chemical binding]; other site
527001011325	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
527001011326	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
527001011327	NAD(P) binding site [chemical binding]; other site
527001011328	catalytic residues [active]
527001011329	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
527001011330	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
527001011331	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
527001011332	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
527001011333	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001011334	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
527001011335	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
527001011336	intersubunit interface [polypeptide binding]; other site
527001011337	active site
527001011338	Zn2+ binding site [ion binding]; other site
527001011339	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
527001011340	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
527001011341	AP (apurinic/apyrimidinic) site pocket; other site
527001011342	DNA interaction; other site
527001011343	Metal-binding active site; metal-binding site
527001011344	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
527001011345	active site
527001011346	dimer interface [polypeptide binding]; other site
527001011347	magnesium binding site [ion binding]; other site
527001011348	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
527001011349	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
527001011350	putative N- and C-terminal domain interface [polypeptide binding]; other site
527001011351	putative active site [active]
527001011352	MgATP binding site [chemical binding]; other site
527001011353	catalytic site [active]
527001011354	metal binding site [ion binding]; metal-binding site
527001011355	putative xylulose binding site [chemical binding]; other site
527001011356	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
527001011357	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
527001011358	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
527001011359	DctM-like transporters; Region: DctM; pfam06808
527001011360	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
527001011361	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
527001011362	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
527001011363	Transcriptional regulator [Transcription]; Region: IclR; COG1414
527001011364	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
527001011365	Bacterial transcriptional regulator; Region: IclR; pfam01614
527001011366	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
527001011367	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
527001011368	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001011369	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001011370	homodimer interface [polypeptide binding]; other site
527001011371	catalytic residue [active]
527001011372	alpha-amylase; Reviewed; Region: malS; PRK09505
527001011373	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
527001011374	active site
527001011375	catalytic site [active]
527001011376	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
527001011377	hypothetical protein; Provisional; Region: PRK10356
527001011378	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
527001011379	putative dimerization interface [polypeptide binding]; other site
527001011380	Transcriptional regulators [Transcription]; Region: PurR; COG1609
527001011381	putative ligand binding site [chemical binding]; other site
527001011382	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001011383	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
527001011384	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001011385	xylose isomerase; Provisional; Region: PRK05474
527001011386	xylose isomerase; Region: xylose_isom_A; TIGR02630
527001011387	xylulokinase; Provisional; Region: PRK15027
527001011388	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
527001011389	N- and C-terminal domain interface [polypeptide binding]; other site
527001011390	active site
527001011391	MgATP binding site [chemical binding]; other site
527001011392	catalytic site [active]
527001011393	metal binding site [ion binding]; metal-binding site
527001011394	xylulose binding site [chemical binding]; other site
527001011395	homodimer interface [polypeptide binding]; other site
527001011396	Predicted membrane protein [Function unknown]; Region: COG4682
527001011397	yiaA/B two helix domain; Region: YiaAB; pfam05360
527001011398	yiaA/B two helix domain; Region: YiaAB; pfam05360
527001011399	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
527001011400	Acyltransferase family; Region: Acyl_transf_3; pfam01757
527001011401	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
527001011402	Acyltransferase family; Region: Acyl_transf_3; pfam01757
527001011403	YsaB-like lipoprotein; Region: YsaB; pfam13983
527001011404	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
527001011405	dimer interface [polypeptide binding]; other site
527001011406	motif 1; other site
527001011407	active site
527001011408	motif 2; other site
527001011409	motif 3; other site
527001011410	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
527001011411	DALR anticodon binding domain; Region: DALR_1; pfam05746
527001011412	Integrase core domain; Region: rve; pfam00665
527001011413	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
527001011414	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001011415	Coenzyme A binding pocket [chemical binding]; other site
527001011416	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
527001011417	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
527001011418	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
527001011419	DNA-binding site [nucleotide binding]; DNA binding site
527001011420	RNA-binding motif; other site
527001011421	Predicted transcriptional regulator [Transcription]; Region: COG2944
527001011422	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001011423	salt bridge; other site
527001011424	non-specific DNA binding site [nucleotide binding]; other site
527001011425	sequence-specific DNA binding site [nucleotide binding]; other site
527001011426	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
527001011427	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
527001011428	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
527001011429	dimerization interface [polypeptide binding]; other site
527001011430	ligand binding site [chemical binding]; other site
527001011431	NADP binding site [chemical binding]; other site
527001011432	catalytic site [active]
527001011433	putative outer membrane lipoprotein; Provisional; Region: PRK10510
527001011434	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
527001011435	ligand binding site [chemical binding]; other site
527001011436	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
527001011437	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
527001011438	molybdopterin cofactor binding site [chemical binding]; other site
527001011439	substrate binding site [chemical binding]; other site
527001011440	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
527001011441	molybdopterin cofactor binding site; other site
527001011442	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001011443	Coenzyme A binding pocket [chemical binding]; other site
527001011444	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
527001011445	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
527001011446	phosphoethanolamine transferase; Provisional; Region: PRK11560
527001011447	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
527001011448	Sulfatase; Region: Sulfatase; pfam00884
527001011449	Transcriptional regulators [Transcription]; Region: PurR; COG1609
527001011450	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001011451	DNA binding site [nucleotide binding]
527001011452	domain linker motif; other site
527001011453	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
527001011454	putative dimerization interface [polypeptide binding]; other site
527001011455	putative ligand binding site [chemical binding]; other site
527001011456	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
527001011457	potential frameshift: common BLAST hit: gi|197364459|ref|YP_002144096.1| putative xanthine permease
527001011458	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
527001011459	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
527001011460	peptide binding site [polypeptide binding]; other site
527001011461	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
527001011462	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001011463	dimer interface [polypeptide binding]; other site
527001011464	conserved gate region; other site
527001011465	putative PBP binding loops; other site
527001011466	ABC-ATPase subunit interface; other site
527001011467	dipeptide transporter; Provisional; Region: PRK10913
527001011468	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
527001011469	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001011470	dimer interface [polypeptide binding]; other site
527001011471	conserved gate region; other site
527001011472	putative PBP binding loops; other site
527001011473	ABC-ATPase subunit interface; other site
527001011474	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
527001011475	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001011476	Walker A/P-loop; other site
527001011477	ATP binding site [chemical binding]; other site
527001011478	Q-loop/lid; other site
527001011479	ABC transporter signature motif; other site
527001011480	Walker B; other site
527001011481	D-loop; other site
527001011482	H-loop/switch region; other site
527001011483	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
527001011484	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
527001011485	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
527001011486	Walker A/P-loop; other site
527001011487	ATP binding site [chemical binding]; other site
527001011488	Q-loop/lid; other site
527001011489	ABC transporter signature motif; other site
527001011490	Walker B; other site
527001011491	D-loop; other site
527001011492	H-loop/switch region; other site
527001011493	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
527001011494	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
527001011495	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
527001011496	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
527001011497	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
527001011498	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
527001011499	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
527001011500	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
527001011501	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
527001011502	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
527001011503	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
527001011504	cell division protein; Provisional; Region: PRK10037
527001011505	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
527001011506	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
527001011507	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
527001011508	DXD motif; other site
527001011509	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
527001011510	PilZ domain; Region: PilZ; pfam07238
527001011511	cellulose synthase regulator protein; Provisional; Region: PRK11114
527001011512	endo-1,4-D-glucanase; Provisional; Region: PRK11097
527001011513	potential frameshift: common BLAST hit: gi|194735245|ref|YP_002116553.1| cellulose synthase subunit BcsC
527001011514	potential frameshift: common BLAST hit: gi|224585412|ref|YP_002639211.1| cellulose synthase subunit BcsC
527001011515	potential frameshift: common BLAST hit: gi|161616676|ref|YP_001590641.1| cellulose synthase subunit BcsC
527001011516	putative diguanylate cyclase; Provisional; Region: PRK13561
527001011517	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001011518	metal binding site [ion binding]; metal-binding site
527001011519	active site
527001011520	I-site; other site
527001011521	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001011522	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
527001011523	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
527001011524	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
527001011525	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
527001011526	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
527001011527	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
527001011528	substrate binding site [chemical binding]; other site
527001011529	ATP binding site [chemical binding]; other site
527001011530	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001011531	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
527001011532	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
527001011533	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001011534	metabolite-proton symporter; Region: 2A0106; TIGR00883
527001011535	putative substrate translocation pore; other site
527001011536	inner membrane protein YhjD; Region: TIGR00766
527001011537	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001011538	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001011539	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
527001011540	putative effector binding pocket; other site
527001011541	putative dimerization interface [polypeptide binding]; other site
527001011542	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
527001011543	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001011544	DNA binding residues [nucleotide binding]
527001011545	dimerization interface [polypeptide binding]; other site
527001011546	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
527001011547	catalytic residue [active]
527001011548	trehalase; Provisional; Region: treF; PRK13270
527001011549	Trehalase; Region: Trehalase; pfam01204
527001011550	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
527001011551	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001011552	DNA-binding site [nucleotide binding]; DNA binding site
527001011553	UTRA domain; Region: UTRA; pfam07702
527001011554	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
527001011555	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
527001011556	putative active site [active]
527001011557	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
527001011558	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cl00216
527001011559	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cl00216
527001011560	glutathione reductase; Validated; Region: PRK06116
527001011561	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
527001011562	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001011563	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
527001011564	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
527001011565	hypothetical protein; Provisional; Region: PRK10215
527001011566	oligopeptidase A; Provisional; Region: PRK10911
527001011567	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
527001011568	active site
527001011569	Zn binding site [ion binding]; other site
527001011570	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001011571	S-adenosylmethionine binding site [chemical binding]; other site
527001011572	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
527001011573	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001011574	putative substrate translocation pore; other site
527001011575	POT family; Region: PTR2; pfam00854
527001011576	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
527001011577	Ligand Binding Site [chemical binding]; other site
527001011578	universal stress protein UspB; Provisional; Region: PRK04960
527001011579	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
527001011580	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
527001011581	Predicted flavoproteins [General function prediction only]; Region: COG2081
527001011582	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
527001011583	Major Facilitator Superfamily; Region: MFS_1; pfam07690
527001011584	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
527001011585	YheO-like PAS domain; Region: PAS_6; pfam08348
527001011586	HTH domain; Region: HTH_22; pfam13309
527001011587	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
527001011588	homotrimer interaction site [polypeptide binding]; other site
527001011589	putative active site [active]
527001011590	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
527001011591	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001011592	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001011593	homodimer interface [polypeptide binding]; other site
527001011594	catalytic residue [active]
527001011595	Major Facilitator Superfamily; Region: MFS_1; pfam07690
527001011596	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001011597	HlyD family secretion protein; Region: HlyD; pfam00529
527001011598	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
527001011599	HlyD family secretion protein; Region: HlyD_3; pfam13437
527001011600	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
527001011601	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
527001011602	Walker A/P-loop; other site
527001011603	ATP binding site [chemical binding]; other site
527001011604	Q-loop/lid; other site
527001011605	ABC transporter signature motif; other site
527001011606	Walker B; other site
527001011607	D-loop; other site
527001011608	H-loop/switch region; other site
527001011609	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
527001011610	Walker A/P-loop; other site
527001011611	ATP binding site [chemical binding]; other site
527001011612	Q-loop/lid; other site
527001011613	ABC transporter signature motif; other site
527001011614	Walker B; other site
527001011615	D-loop; other site
527001011616	H-loop/switch region; other site
527001011617	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
527001011618	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
527001011619	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
527001011620	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
527001011621	nickel responsive regulator; Provisional; Region: PRK02967
527001011622	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
527001011623	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
527001011624	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
527001011625	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
527001011626	Domain of unknown function DUF20; Region: UPF0118; pfam01594
527001011627	major facilitator superfamily transporter; Provisional; Region: PRK05122
527001011628	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001011629	putative substrate translocation pore; other site
527001011630	hypothetical protein; Provisional; Region: PRK11615
527001011631	hypothetical protein; Provisional; Region: PRK11212
527001011632	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
527001011633	CPxP  motif; other site
527001011634	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
527001011635	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
527001011636	dimer interface [polypeptide binding]; other site
527001011637	ligand binding site [chemical binding]; other site
527001011638	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001011639	dimerization interface [polypeptide binding]; other site
527001011640	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
527001011641	dimer interface [polypeptide binding]; other site
527001011642	putative CheW interface [polypeptide binding]; other site
527001011643	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
527001011644	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
527001011645	metal-binding site [ion binding]
527001011646	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
527001011647	Predicted membrane protein [Function unknown]; Region: COG3714
527001011648	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
527001011649	hypothetical protein; Provisional; Region: PRK10910
527001011650	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
527001011651	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001011652	S-adenosylmethionine binding site [chemical binding]; other site
527001011653	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
527001011654	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
527001011655	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
527001011656	P loop; other site
527001011657	GTP binding site [chemical binding]; other site
527001011658	cell division protein FtsE; Provisional; Region: PRK10908
527001011659	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001011660	Walker A/P-loop; other site
527001011661	ATP binding site [chemical binding]; other site
527001011662	Q-loop/lid; other site
527001011663	ABC transporter signature motif; other site
527001011664	Walker B; other site
527001011665	D-loop; other site
527001011666	H-loop/switch region; other site
527001011667	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
527001011668	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
527001011669	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
527001011670	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
527001011671	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
527001011672	DNA binding residues [nucleotide binding]
527001011673	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
527001011674	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
527001011675	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
527001011676	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
527001011677	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
527001011678	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
527001011679	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
527001011680	dimerization interface [polypeptide binding]; other site
527001011681	ligand binding site [chemical binding]; other site
527001011682	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
527001011683	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
527001011684	TM-ABC transporter signature motif; other site
527001011685	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
527001011686	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
527001011687	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
527001011688	TM-ABC transporter signature motif; other site
527001011689	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
527001011690	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
527001011691	Walker A/P-loop; other site
527001011692	ATP binding site [chemical binding]; other site
527001011693	Q-loop/lid; other site
527001011694	ABC transporter signature motif; other site
527001011695	Walker B; other site
527001011696	D-loop; other site
527001011697	H-loop/switch region; other site
527001011698	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
527001011699	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
527001011700	Walker A/P-loop; other site
527001011701	ATP binding site [chemical binding]; other site
527001011702	Q-loop/lid; other site
527001011703	ABC transporter signature motif; other site
527001011704	Walker B; other site
527001011705	D-loop; other site
527001011706	H-loop/switch region; other site
527001011707	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
527001011708	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
527001011709	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
527001011710	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001011711	dimer interface [polypeptide binding]; other site
527001011712	conserved gate region; other site
527001011713	putative PBP binding loops; other site
527001011714	ABC-ATPase subunit interface; other site
527001011715	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
527001011716	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001011717	dimer interface [polypeptide binding]; other site
527001011718	conserved gate region; other site
527001011719	ABC-ATPase subunit interface; other site
527001011720	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
527001011721	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
527001011722	Walker A/P-loop; other site
527001011723	ATP binding site [chemical binding]; other site
527001011724	Q-loop/lid; other site
527001011725	ABC transporter signature motif; other site
527001011726	Walker B; other site
527001011727	D-loop; other site
527001011728	H-loop/switch region; other site
527001011729	TOBE domain; Region: TOBE_2; pfam08402
527001011730	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
527001011731	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
527001011732	putative active site [active]
527001011733	catalytic site [active]
527001011734	putative metal binding site [ion binding]; other site
527001011735	hypothetical protein; Provisional; Region: PRK10350
527001011736	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
527001011737	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
527001011738	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
527001011739	active site
527001011740	substrate binding pocket [chemical binding]; other site
527001011741	homodimer interaction site [polypeptide binding]; other site
527001011742	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
527001011743	Protein of unknown function, DUF606; Region: DUF606; pfam04657
527001011744	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
527001011745	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
527001011746	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
527001011747	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
527001011748	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
527001011749	substrate binding site [chemical binding]; other site
527001011750	dimer interface [polypeptide binding]; other site
527001011751	ATP binding site [chemical binding]; other site
527001011752	putative acetyltransferase YhhY; Provisional; Region: PRK10140
527001011753	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001011754	Coenzyme A binding pocket [chemical binding]; other site
527001011755	putative oxidoreductase; Provisional; Region: PRK10206
527001011756	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
527001011757	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
527001011758	Pirin-related protein [General function prediction only]; Region: COG1741
527001011759	Pirin; Region: Pirin; pfam02678
527001011760	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
527001011761	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001011762	DNA binding site [nucleotide binding]
527001011763	domain linker motif; other site
527001011764	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
527001011765	putative ligand binding site [chemical binding]; other site
527001011766	putative dimerization interface [polypeptide binding]; other site
527001011767	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
527001011768	low affinity gluconate transporter; Provisional; Region: PRK10472
527001011769	gluconate transporter; Region: gntP; TIGR00791
527001011770	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
527001011771	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
527001011772	glycogen branching enzyme; Provisional; Region: PRK05402
527001011773	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
527001011774	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
527001011775	active site
527001011776	catalytic site [active]
527001011777	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
527001011778	glycogen debranching enzyme; Provisional; Region: PRK03705
527001011779	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
527001011780	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
527001011781	active site
527001011782	catalytic site [active]
527001011783	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
527001011784	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
527001011785	ligand binding site; other site
527001011786	oligomer interface; other site
527001011787	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
527001011788	dimer interface [polypeptide binding]; other site
527001011789	N-terminal domain interface [polypeptide binding]; other site
527001011790	sulfate 1 binding site; other site
527001011791	glycogen synthase; Provisional; Region: glgA; PRK00654
527001011792	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
527001011793	ADP-binding pocket [chemical binding]; other site
527001011794	homodimer interface [polypeptide binding]; other site
527001011795	glycogen phosphorylase; Provisional; Region: PRK14986
527001011796	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
527001011797	homodimer interface [polypeptide binding]; other site
527001011798	active site pocket [active]
527001011799	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
527001011800	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
527001011801	active site residue [active]
527001011802	intramembrane serine protease GlpG; Provisional; Region: PRK10907
527001011803	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
527001011804	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
527001011805	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
527001011806	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
527001011807	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001011808	transcriptional regulator MalT; Provisional; Region: PRK04841
527001011809	AAA ATPase domain; Region: AAA_16; pfam13191
527001011810	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001011811	DNA binding residues [nucleotide binding]
527001011812	dimerization interface [polypeptide binding]; other site
527001011813	maltodextrin phosphorylase; Provisional; Region: PRK14985
527001011814	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
527001011815	homodimer interface [polypeptide binding]; other site
527001011816	active site pocket [active]
527001011817	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
527001011818	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
527001011819	high-affinity gluconate transporter; Provisional; Region: PRK14984
527001011820	gluconate transporter; Region: gntP; TIGR00791
527001011821	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
527001011822	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
527001011823	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
527001011824	DNA utilization protein GntX; Provisional; Region: PRK11595
527001011825	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
527001011826	active site
527001011827	carboxylesterase BioH; Provisional; Region: PRK10349
527001011828	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
527001011829	hypothetical protein; Provisional; Region: PRK09956
527001011830	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
527001011831	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
527001011832	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
527001011833	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
527001011834	G1 box; other site
527001011835	GTP/Mg2+ binding site [chemical binding]; other site
527001011836	Switch I region; other site
527001011837	G2 box; other site
527001011838	G3 box; other site
527001011839	Switch II region; other site
527001011840	G4 box; other site
527001011841	G5 box; other site
527001011842	Nucleoside recognition; Region: Gate; pfam07670
527001011843	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
527001011844	Nucleoside recognition; Region: Gate; pfam07670
527001011845	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
527001011846	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
527001011847	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
527001011848	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
527001011849	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
527001011850	RNA binding site [nucleotide binding]; other site
527001011851	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
527001011852	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
527001011853	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
527001011854	osmolarity response regulator; Provisional; Region: ompR; PRK09468
527001011855	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001011856	active site
527001011857	phosphorylation site [posttranslational modification]
527001011858	intermolecular recognition site; other site
527001011859	dimerization interface [polypeptide binding]; other site
527001011860	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001011861	DNA binding site [nucleotide binding]
527001011862	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
527001011863	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
527001011864	dimerization interface [polypeptide binding]; other site
527001011865	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001011866	dimer interface [polypeptide binding]; other site
527001011867	phosphorylation site [posttranslational modification]
527001011868	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001011869	ATP binding site [chemical binding]; other site
527001011870	G-X-G motif; other site
527001011871	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
527001011872	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
527001011873	active site
527001011874	substrate-binding site [chemical binding]; other site
527001011875	metal-binding site [ion binding]
527001011876	ATP binding site [chemical binding]; other site
527001011877	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
527001011878	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
527001011879	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
527001011880	dimerization interface [polypeptide binding]; other site
527001011881	domain crossover interface; other site
527001011882	redox-dependent activation switch; other site
527001011883	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
527001011884	RNA binding surface [nucleotide binding]; other site
527001011885	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
527001011886	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001011887	motif II; other site
527001011888	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
527001011889	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
527001011890	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
527001011891	ADP-ribose binding site [chemical binding]; other site
527001011892	dimer interface [polypeptide binding]; other site
527001011893	active site
527001011894	nudix motif; other site
527001011895	metal binding site [ion binding]; metal-binding site
527001011896	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
527001011897	Transglycosylase; Region: Transgly; pfam00912
527001011898	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
527001011899	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
527001011900	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
527001011901	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
527001011902	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
527001011903	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
527001011904	shikimate kinase; Reviewed; Region: aroK; PRK00131
527001011905	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
527001011906	ADP binding site [chemical binding]; other site
527001011907	magnesium binding site [ion binding]; other site
527001011908	putative shikimate binding site; other site
527001011909	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
527001011910	active site
527001011911	dimer interface [polypeptide binding]; other site
527001011912	metal binding site [ion binding]; metal-binding site
527001011913	cell division protein DamX; Validated; Region: PRK10905
527001011914	DNA adenine methylase; Provisional; Region: PRK10904
527001011915	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
527001011916	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
527001011917	substrate binding site [chemical binding]; other site
527001011918	hexamer interface [polypeptide binding]; other site
527001011919	metal binding site [ion binding]; metal-binding site
527001011920	phosphoglycolate phosphatase; Provisional; Region: PRK13222
527001011921	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001011922	motif II; other site
527001011923	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
527001011924	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
527001011925	active site
527001011926	HIGH motif; other site
527001011927	dimer interface [polypeptide binding]; other site
527001011928	KMSKS motif; other site
527001011929	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
527001011930	Autotransporter beta-domain; Region: Autotransporter; pfam03797
527001011931	siroheme synthase; Provisional; Region: cysG; PRK10637
527001011932	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
527001011933	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
527001011934	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
527001011935	active site
527001011936	SAM binding site [chemical binding]; other site
527001011937	homodimer interface [polypeptide binding]; other site
527001011938	nitrite transporter NirC; Provisional; Region: PRK11562
527001011939	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
527001011940	nitrite reductase subunit NirD; Provisional; Region: PRK14989
527001011941	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
527001011942	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
527001011943	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
527001011944	putative transporter; Provisional; Region: PRK03699
527001011945	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001011946	putative substrate translocation pore; other site
527001011947	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
527001011948	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
527001011949	substrate binding site [chemical binding]; other site
527001011950	hypothetical protein; Provisional; Region: PRK10204
527001011951	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
527001011952	cell filamentation protein Fic; Provisional; Region: PRK10347
527001011953	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
527001011954	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
527001011955	glutamine binding [chemical binding]; other site
527001011956	catalytic triad [active]
527001011957	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
527001011958	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
527001011959	inhibitor-cofactor binding pocket; inhibition site
527001011960	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001011961	catalytic residue [active]
527001011962	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
527001011963	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
527001011964	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
527001011965	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
527001011966	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
527001011967	ligand binding site [chemical binding]; other site
527001011968	flexible hinge region; other site
527001011969	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
527001011970	putative switch regulator; other site
527001011971	non-specific DNA interactions [nucleotide binding]; other site
527001011972	DNA binding site [nucleotide binding]
527001011973	sequence specific DNA binding site [nucleotide binding]; other site
527001011974	putative cAMP binding site [chemical binding]; other site
527001011975	hypothetical protein; Provisional; Region: PRK10738
527001011976	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
527001011977	active site
527001011978	hypothetical protein; Provisional; Region: PRK04966
527001011979	potential frameshift: common BLAST hit: gi|197364310|ref|YP_002143947.1| putative hydrolase
527001011980	putative monooxygenase; Provisional; Region: PRK11118
527001011981	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001011982	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001011983	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
527001011984	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001011985	Walker A/P-loop; other site
527001011986	ATP binding site [chemical binding]; other site
527001011987	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
527001011988	ABC transporter signature motif; other site
527001011989	Walker B; other site
527001011990	D-loop; other site
527001011991	ABC transporter; Region: ABC_tran_2; pfam12848
527001011992	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
527001011993	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
527001011994	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
527001011995	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
527001011996	TrkA-N domain; Region: TrkA_N; pfam02254
527001011997	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
527001011998	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
527001011999	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
527001012000	phi X174 lysis protein; Provisional; Region: PRK02793
527001012001	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
527001012002	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
527001012003	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
527001012004	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
527001012005	YheO-like PAS domain; Region: PAS_6; pfam08348
527001012006	HTH domain; Region: HTH_22; pfam13309
527001012007	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
527001012008	sulfur relay protein TusC; Validated; Region: PRK00211
527001012009	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
527001012010	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
527001012011	S17 interaction site [polypeptide binding]; other site
527001012012	S8 interaction site; other site
527001012013	16S rRNA interaction site [nucleotide binding]; other site
527001012014	streptomycin interaction site [chemical binding]; other site
527001012015	23S rRNA interaction site [nucleotide binding]; other site
527001012016	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
527001012017	30S ribosomal protein S7; Validated; Region: PRK05302
527001012018	elongation factor G; Reviewed; Region: PRK00007
527001012019	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
527001012020	G1 box; other site
527001012021	putative GEF interaction site [polypeptide binding]; other site
527001012022	GTP/Mg2+ binding site [chemical binding]; other site
527001012023	Switch I region; other site
527001012024	G2 box; other site
527001012025	G3 box; other site
527001012026	Switch II region; other site
527001012027	G4 box; other site
527001012028	G5 box; other site
527001012029	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
527001012030	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
527001012031	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
527001012032	elongation factor Tu; Reviewed; Region: PRK00049
527001012033	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
527001012034	G1 box; other site
527001012035	GEF interaction site [polypeptide binding]; other site
527001012036	GTP/Mg2+ binding site [chemical binding]; other site
527001012037	Switch I region; other site
527001012038	G2 box; other site
527001012039	G3 box; other site
527001012040	Switch II region; other site
527001012041	G4 box; other site
527001012042	G5 box; other site
527001012043	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
527001012044	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
527001012045	Antibiotic Binding Site [chemical binding]; other site
527001012046	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
527001012047	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
527001012048	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
527001012049	heme binding site [chemical binding]; other site
527001012050	ferroxidase pore; other site
527001012051	ferroxidase diiron center [ion binding]; other site
527001012052	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
527001012053	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
527001012054	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
527001012055	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
527001012056	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
527001012057	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
527001012058	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
527001012059	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
527001012060	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
527001012061	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
527001012062	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
527001012063	protein-rRNA interface [nucleotide binding]; other site
527001012064	putative translocon binding site; other site
527001012065	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
527001012066	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
527001012067	G-X-X-G motif; other site
527001012068	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
527001012069	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
527001012070	23S rRNA interface [nucleotide binding]; other site
527001012071	5S rRNA interface [nucleotide binding]; other site
527001012072	putative antibiotic binding site [chemical binding]; other site
527001012073	L25 interface [polypeptide binding]; other site
527001012074	L27 interface [polypeptide binding]; other site
527001012075	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
527001012076	23S rRNA interface [nucleotide binding]; other site
527001012077	putative translocon interaction site; other site
527001012078	signal recognition particle (SRP54) interaction site; other site
527001012079	L23 interface [polypeptide binding]; other site
527001012080	trigger factor interaction site; other site
527001012081	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
527001012082	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
527001012083	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
527001012084	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
527001012085	RNA binding site [nucleotide binding]; other site
527001012086	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
527001012087	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
527001012088	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
527001012089	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
527001012090	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
527001012091	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
527001012092	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
527001012093	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
527001012094	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
527001012095	23S rRNA interface [nucleotide binding]; other site
527001012096	5S rRNA interface [nucleotide binding]; other site
527001012097	L27 interface [polypeptide binding]; other site
527001012098	L5 interface [polypeptide binding]; other site
527001012099	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
527001012100	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
527001012101	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
527001012102	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
527001012103	23S rRNA binding site [nucleotide binding]; other site
527001012104	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
527001012105	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
527001012106	SecY translocase; Region: SecY; pfam00344
527001012107	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
527001012108	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
527001012109	30S ribosomal protein S13; Region: bact_S13; TIGR03631
527001012110	30S ribosomal protein S11; Validated; Region: PRK05309
527001012111	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
527001012112	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
527001012113	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
527001012114	RNA binding surface [nucleotide binding]; other site
527001012115	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
527001012116	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
527001012117	alphaNTD homodimer interface [polypeptide binding]; other site
527001012118	alphaNTD - beta interaction site [polypeptide binding]; other site
527001012119	alphaNTD - beta' interaction site [polypeptide binding]; other site
527001012120	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
527001012121	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
527001012122	hypothetical protein; Provisional; Region: PRK10203
527001012123	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
527001012124	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
527001012125	DNA binding residues [nucleotide binding]
527001012126	dimer interface [polypeptide binding]; other site
527001012127	metal binding site [ion binding]; metal-binding site
527001012128	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
527001012129	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
527001012130	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
527001012131	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
527001012132	TrkA-N domain; Region: TrkA_N; pfam02254
527001012133	TrkA-C domain; Region: TrkA_C; pfam02080
527001012134	TrkA-N domain; Region: TrkA_N; pfam02254
527001012135	TrkA-C domain; Region: TrkA_C; pfam02080
527001012136	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
527001012137	putative RNA binding site [nucleotide binding]; other site
527001012138	16S rRNA methyltransferase B; Provisional; Region: PRK10901
527001012139	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001012140	S-adenosylmethionine binding site [chemical binding]; other site
527001012141	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
527001012142	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
527001012143	putative active site [active]
527001012144	substrate binding site [chemical binding]; other site
527001012145	putative cosubstrate binding site; other site
527001012146	catalytic site [active]
527001012147	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
527001012148	substrate binding site [chemical binding]; other site
527001012149	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
527001012150	active site
527001012151	catalytic residues [active]
527001012152	metal binding site [ion binding]; metal-binding site
527001012153	hypothetical protein; Provisional; Region: PRK10736
527001012154	DNA protecting protein DprA; Region: dprA; TIGR00732
527001012155	hypothetical protein; Validated; Region: PRK03430
527001012156	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
527001012157	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
527001012158	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
527001012159	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
527001012160	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
527001012161	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
527001012162	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
527001012163	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
527001012164	shikimate binding site; other site
527001012165	NAD(P) binding site [chemical binding]; other site
527001012166	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
527001012167	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
527001012168	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
527001012169	trimer interface [polypeptide binding]; other site
527001012170	putative metal binding site [ion binding]; other site
527001012171	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
527001012172	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001012173	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
527001012174	Coenzyme A binding pocket [chemical binding]; other site
527001012175	homoserine O-succinyltransferase; Provisional; Region: PRK05368
527001012176	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
527001012177	proposed active site lysine [active]
527001012178	conserved cys residue [active]
527001012179	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
527001012180	malate synthase A; Region: malate_syn_A; TIGR01344
527001012181	active site
527001012182	isocitrate lyase; Provisional; Region: PRK15063
527001012183	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
527001012184	tetramer interface [polypeptide binding]; other site
527001012185	active site
527001012186	Mg2+/Mn2+ binding site [ion binding]; other site
527001012187	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
527001012188	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
527001012189	transcriptional repressor IclR; Provisional; Region: PRK11569
527001012190	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
527001012191	Bacterial transcriptional regulator; Region: IclR; pfam01614
527001012192	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
527001012193	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
527001012194	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
527001012195	substrate binding pocket [chemical binding]; other site
527001012196	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
527001012197	B12 binding site [chemical binding]; other site
527001012198	cobalt ligand [ion binding]; other site
527001012199	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
527001012200	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
527001012201	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
527001012202	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
527001012203	active site pocket [active]
527001012204	oxyanion hole [active]
527001012205	catalytic triad [active]
527001012206	active site nucleophile [active]
527001012207	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
527001012208	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
527001012209	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
527001012210	RNA binding surface [nucleotide binding]; other site
527001012211	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
527001012212	probable active site [active]
527001012213	hypothetical protein; Provisional; Region: PRK10515
527001012214	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
527001012215	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
527001012216	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001012217	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
527001012218	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
527001012219	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
527001012220	active site
527001012221	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
527001012222	phosphate binding site [ion binding]; other site
527001012223	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
527001012224	aspartate kinase III; Validated; Region: PRK09084
527001012225	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
527001012226	nucleotide binding site [chemical binding]; other site
527001012227	substrate binding site [chemical binding]; other site
527001012228	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
527001012229	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
527001012230	dimer interface [polypeptide binding]; other site
527001012231	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
527001012232	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
527001012233	active site
527001012234	dimer interface [polypeptide binding]; other site
527001012235	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
527001012236	dimer interface [polypeptide binding]; other site
527001012237	active site
527001012238	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
527001012239	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
527001012240	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
527001012241	Predicted membrane protein [Function unknown]; Region: COG3223
527001012242	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
527001012243	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001012244	dimer interface [polypeptide binding]; other site
527001012245	conserved gate region; other site
527001012246	putative PBP binding loops; other site
527001012247	ABC-ATPase subunit interface; other site
527001012248	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
527001012249	dimer interface [polypeptide binding]; other site
527001012250	conserved gate region; other site
527001012251	putative PBP binding loops; other site
527001012252	ABC-ATPase subunit interface; other site
527001012253	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
527001012254	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
527001012255	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
527001012256	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
527001012257	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
527001012258	Walker A/P-loop; other site
527001012259	ATP binding site [chemical binding]; other site
527001012260	Q-loop/lid; other site
527001012261	ABC transporter signature motif; other site
527001012262	Walker B; other site
527001012263	D-loop; other site
527001012264	H-loop/switch region; other site
527001012265	TOBE domain; Region: TOBE_2; pfam08402
527001012266	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
527001012267	trimer interface; other site
527001012268	sugar binding site [chemical binding]; other site
527001012269	maltose regulon periplasmic protein; Provisional; Region: PRK10564
527001012270	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
527001012271	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
527001012272	UbiA prenyltransferase family; Region: UbiA; pfam01040
527001012273	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
527001012274	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
527001012275	putative acyl-acceptor binding pocket; other site
527001012276	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
527001012277	LexA repressor; Validated; Region: PRK00215
527001012278	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
527001012279	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
527001012280	Catalytic site [active]
527001012281	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
527001012282	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
527001012283	hypothetical protein; Provisional; Region: PRK10428
527001012284	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
527001012285	metal binding site 2 [ion binding]; metal-binding site
527001012286	putative DNA binding helix; other site
527001012287	metal binding site 1 [ion binding]; metal-binding site
527001012288	dimer interface [polypeptide binding]; other site
527001012289	structural Zn2+ binding site [ion binding]; other site
527001012290	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
527001012291	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
527001012292	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
527001012293	FMN binding site [chemical binding]; other site
527001012294	active site
527001012295	catalytic residues [active]
527001012296	substrate binding site [chemical binding]; other site
527001012297	phage shock protein G; Reviewed; Region: pspG; PRK09459
527001012298	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
527001012299	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
527001012300	NADP binding site [chemical binding]; other site
527001012301	dimer interface [polypeptide binding]; other site
527001012302	replicative DNA helicase; Provisional; Region: PRK08006
527001012303	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
527001012304	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
527001012305	Walker A motif; other site
527001012306	ATP binding site [chemical binding]; other site
527001012307	Walker B motif; other site
527001012308	DNA binding loops [nucleotide binding]
527001012309	alanine racemase; Reviewed; Region: alr; PRK00053
527001012310	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
527001012311	active site
527001012312	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
527001012313	substrate binding site [chemical binding]; other site
527001012314	catalytic residues [active]
527001012315	dimer interface [polypeptide binding]; other site
527001012316	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
527001012317	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
527001012318	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001012319	homodimer interface [polypeptide binding]; other site
527001012320	catalytic residue [active]
527001012321	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001012322	active site
527001012323	motif I; other site
527001012324	motif II; other site
527001012325	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
527001012326	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
527001012327	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
527001012328	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
527001012329	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
527001012330	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
527001012331	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
527001012332	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
527001012333	dimer interface [polypeptide binding]; other site
527001012334	ssDNA binding site [nucleotide binding]; other site
527001012335	tetramer (dimer of dimers) interface [polypeptide binding]; other site
527001012336	hypothetical protein; Validated; Region: PRK09039
527001012337	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
527001012338	Outer membrane efflux protein; Region: OEP; pfam02321
527001012339	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
527001012340	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
527001012341	HlyD family secretion protein; Region: HlyD_3; pfam13437
527001012342	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012343	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012344	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012345	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012346	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
527001012347	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
527001012348	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012349	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
527001012350	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
527001012351	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012352	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
527001012353	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
527001012354	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012355	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
527001012356	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
527001012357	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012358	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
527001012359	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012360	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
527001012361	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
527001012362	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012363	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
527001012364	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012365	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
527001012366	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012367	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012368	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
527001012369	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012370	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012371	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012372	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012373	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012374	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012375	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
527001012376	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012377	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012378	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012379	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012380	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
527001012381	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012382	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012383	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012384	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012385	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
527001012386	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
527001012387	Walker A/P-loop; other site
527001012388	ATP binding site [chemical binding]; other site
527001012389	Q-loop/lid; other site
527001012390	ABC transporter signature motif; other site
527001012391	Walker B; other site
527001012392	D-loop; other site
527001012393	H-loop/switch region; other site
527001012394	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
527001012395	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
527001012396	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
527001012397	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
527001012398	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001012399	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
527001012400	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
527001012401	DNA binding residues [nucleotide binding]
527001012402	dimer interface [polypeptide binding]; other site
527001012403	[2Fe-2S] cluster binding site [ion binding]; other site
527001012404	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
527001012405	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
527001012406	putative C-terminal domain interface [polypeptide binding]; other site
527001012407	putative GSH binding site (G-site) [chemical binding]; other site
527001012408	putative dimer interface [polypeptide binding]; other site
527001012409	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
527001012410	putative N-terminal domain interface [polypeptide binding]; other site
527001012411	putative dimer interface [polypeptide binding]; other site
527001012412	putative substrate binding pocket (H-site) [chemical binding]; other site
527001012413	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
527001012414	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
527001012415	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
527001012416	Transcriptional regulator [Transcription]; Region: LysR; COG0583
527001012417	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001012418	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
527001012419	putative dimerization interface [polypeptide binding]; other site
527001012420	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
527001012421	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
527001012422	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
527001012423	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
527001012424	Na binding site [ion binding]; other site
527001012425	Predicted membrane protein [Function unknown]; Region: COG3162
527001012426	acetyl-CoA synthetase; Provisional; Region: PRK00174
527001012427	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
527001012428	active site
527001012429	CoA binding site [chemical binding]; other site
527001012430	acyl-activating enzyme (AAE) consensus motif; other site
527001012431	AMP binding site [chemical binding]; other site
527001012432	acetate binding site [chemical binding]; other site
527001012433	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
527001012434	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
527001012435	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
527001012436	potential frameshift: common BLAST hit: gi|197365005|ref|YP_002144642.1| cytochrome c-type biogenesis protein
527001012437	heme lyase subunit NrfE; Provisional; Region: PRK10369
527001012438	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
527001012439	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
527001012440	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
527001012441	binding surface
527001012442	TPR motif; other site
527001012443	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
527001012444	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
527001012445	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
527001012446	Sel1-like repeats; Region: SEL1; smart00671
527001012447	potential frameshift: common BLAST hit: gi|29144454|ref|NP_807796.1| formate dehydrogenase H
527001012448	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
527001012449	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001012450	Coenzyme A binding pocket [chemical binding]; other site
527001012451	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
527001012452	dimer interface [polypeptide binding]; other site
527001012453	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
527001012454	hypothetical protein; Provisional; Region: PRK10220
527001012455	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
527001012456	PhnA protein; Region: PhnA; pfam03831
527001012457	proline/glycine betaine transporter; Provisional; Region: PRK10642
527001012458	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001012459	putative substrate translocation pore; other site
527001012460	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
527001012461	sensor protein BasS/PmrB; Provisional; Region: PRK10755
527001012462	HAMP domain; Region: HAMP; pfam00672
527001012463	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001012464	dimer interface [polypeptide binding]; other site
527001012465	phosphorylation site [posttranslational modification]
527001012466	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001012467	ATP binding site [chemical binding]; other site
527001012468	Mg2+ binding site [ion binding]; other site
527001012469	G-X-G motif; other site
527001012470	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
527001012471	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001012472	active site
527001012473	phosphorylation site [posttranslational modification]
527001012474	intermolecular recognition site; other site
527001012475	dimerization interface [polypeptide binding]; other site
527001012476	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001012477	DNA binding site [nucleotide binding]
527001012478	putative metal dependent hydrolase; Provisional; Region: PRK11598
527001012479	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
527001012480	Sulfatase; Region: Sulfatase; pfam00884
527001012481	arginine:agmatin antiporter; Provisional; Region: PRK10644
527001012482	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
527001012483	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001012484	arginine decarboxylase; Provisional; Region: PRK15029
527001012485	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
527001012486	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
527001012487	homodimer interface [polypeptide binding]; other site
527001012488	pyridoxal 5'-phosphate binding site [chemical binding]; other site
527001012489	catalytic residue [active]
527001012490	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
527001012491	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
527001012492	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001012493	alpha-galactosidase; Provisional; Region: PRK15076
527001012494	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
527001012495	NAD binding site [chemical binding]; other site
527001012496	sugar binding site [chemical binding]; other site
527001012497	divalent metal binding site [ion binding]; other site
527001012498	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
527001012499	dimer interface [polypeptide binding]; other site
527001012500	melibiose:sodium symporter; Provisional; Region: PRK10429
527001012501	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
527001012502	fumarate hydratase; Provisional; Region: PRK15389
527001012503	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
527001012504	Fumarase C-terminus; Region: Fumerase_C; pfam05683
527001012505	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
527001012506	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
527001012507	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
527001012508	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001012509	active site
527001012510	phosphorylation site [posttranslational modification]
527001012511	intermolecular recognition site; other site
527001012512	dimerization interface [polypeptide binding]; other site
527001012513	sensory histidine kinase DcuS; Provisional; Region: PRK11086
527001012514	PAS domain; Region: PAS; smart00091
527001012515	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001012516	ATP binding site [chemical binding]; other site
527001012517	Mg2+ binding site [ion binding]; other site
527001012518	G-X-G motif; other site
527001012519	potential frameshift: common BLAST hit: gi|194451743|ref|YP_002048296.1| anaerobic dimethyl sulfoxide reductase chain a
527001012520	potential frameshift: common BLAST hit: gi|197250345|ref|YP_002149220.1| anaerobic dimethyl sulfoxide reductase chain a
527001012521	potential frameshift: common BLAST hit: gi|197249022|ref|YP_002149221.1| dimethylsulfoxide reductase, chain B
527001012522	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
527001012523	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
527001012524	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
527001012525	SdiA-regulated; Region: SdiA-regulated; pfam06977
527001012526	SdiA-regulated; Region: SdiA-regulated; cd09971
527001012527	putative active site [active]
527001012528	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
527001012529	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
527001012530	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001012531	DNA binding residues [nucleotide binding]
527001012532	dimerization interface [polypeptide binding]; other site
527001012533	AraC family transcriptional regulator; Provisional; Region: PRK15186
527001012534	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001012535	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
527001012536	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001012537	Coenzyme A binding pocket [chemical binding]; other site
527001012538	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
527001012539	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
527001012540	active site
527001012541	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
527001012542	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
527001012543	P-loop; other site
527001012544	Magnesium ion binding site [ion binding]; other site
527001012545	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
527001012546	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
527001012547	replicative DNA helicase; Region: DnaB; TIGR00665
527001012548	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
527001012549	Walker A motif; other site
527001012550	ATP binding site [chemical binding]; other site
527001012551	Walker B motif; other site
527001012552	DNA binding loops [nucleotide binding]
527001012553	integrating conjugative element, PFGI_1 class, ParB family protein; Region: ICE_PFGI_1_parB; TIGR03764
527001012554	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
527001012555	Protein of unknown function (DUF2786); Region: DUF2786; pfam10979
527001012556	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
527001012557	Helix-turn-helix domain; Region: HTH_36; pfam13730
527001012558	integrating conjugative element protein, PFL_4669 family; Region: ICE_PFL4669; TIGR03761
527001012559	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
527001012560	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
527001012561	active site
527001012562	putative interdomain interaction site [polypeptide binding]; other site
527001012563	putative metal-binding site [ion binding]; other site
527001012564	putative nucleotide binding site [chemical binding]; other site
527001012565	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
527001012566	domain I; other site
527001012567	DNA binding groove [nucleotide binding]
527001012568	phosphate binding site [ion binding]; other site
527001012569	domain II; other site
527001012570	domain III; other site
527001012571	nucleotide binding site [chemical binding]; other site
527001012572	catalytic site [active]
527001012573	domain IV; other site
527001012574	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
527001012575	Protein of unknown function (DUF3577); Region: DUF3577; pfam12101
527001012576	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
527001012577	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
527001012578	dimer interface [polypeptide binding]; other site
527001012579	ssDNA binding site [nucleotide binding]; other site
527001012580	tetramer (dimer of dimers) interface [polypeptide binding]; other site
527001012581	putative single-stranded DNA-binding protein; Region: PHA01740
527001012582	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
527001012583	conjugative transfer region protein, TIGR03748 family; Region: conj_PilL
527001012584	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
527001012585	PilM; Region: PilM; pfam07419
527001012586	potential frameshift: common BLAST hit: gi|83404883|ref|YP_424898.1| PilN
527001012587	Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864
527001012588	type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021
527001012589	Type II/IV secretion system protein; Region: T2SE; pfam00437
527001012590	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
527001012591	Walker A motif; other site
527001012592	ATP binding site [chemical binding]; other site
527001012593	Walker B motif; other site
527001012594	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
527001012595	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
527001012596	PilS N terminal; Region: PilS; pfam08805
527001012597	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
527001012598	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
527001012599	N-acetyl-D-glucosamine binding site [chemical binding]; other site
527001012600	catalytic residue [active]
527001012601	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
527001012602	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
527001012603	Rci recombinase, C-terminal catalytic domain.  Rci enzymes are found in IncI1 incompatibility group plasmids such as R64.  These recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain...; Region: INT_Rci; cd00796
527001012604	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
527001012605	catalytic residues [active]
527001012606	Int/Topo IB signature motif; other site
527001012607	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
527001012608	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
527001012609	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
527001012610	N-acetyl-D-glucosamine binding site [chemical binding]; other site
527001012611	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
527001012612	Restriction endonuclease; Region: Mrr_cat; pfam04471
527001012613	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
527001012614	conjugative coupling factor TraD, TOL family; Region: conj_TOL_TraD; TIGR03754
527001012615	Domain of unknown function (DUF4400); Region: DUF4400; cl14023
527001012616	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
527001012617	integrative conjugative element protein, RAQPRD family; Region: ICE_RAQPRD; TIGR01690
527001012618	Protein of unknown function (DUF3262); Region: DUF3262; pfam11660
527001012619	integrating conjugative element membrane protein, PFL_4702 family; Region: conj_TIGR03745
527001012620	Protein of unknown function (DUF3487); Region: DUF3487; cl13432
527001012621	integrating conjugative element protein, PFL_4703 family; Region: conj_TIGR03746
527001012622	Protein of unknown function (DUF3438); Region: DUF3438; cl13372
527001012623	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
527001012624	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
527001012625	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
527001012626	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
527001012627	AAA-like domain; Region: AAA_10; pfam12846
527001012628	integrating conjugative element protein, PFL_4709 family; Region: conj_TIGR03757
527001012629	integrating conjugative element protein, PFL_4710 family; Region: conj_TIGR03756
527001012630	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
527001012631	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
527001012632	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
527001012633	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
527001012634	Active Sites [active]
527001012635	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
527001012636	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
527001012637	ParB-like nuclease domain; Region: ParB; smart00470
527001012638	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
527001012639	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
527001012640	Integrase; Region: Integrase_1; pfam12835
527001012641	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
527001012642	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
527001012643	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
527001012644	Protein of unknown function (DUF3085); Region: DUF3085; pfam11284
527001012645	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
527001012646	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
527001012647	active site
527001012648	DNA binding site [nucleotide binding]
527001012649	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
527001012650	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
527001012651	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
527001012652	tail protein; Provisional; Region: D; PHA02561
527001012653	Phage protein U [General function prediction only]; Region: COG3499
527001012654	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
527001012655	membrane protein P6; Region: PHA01399
527001012656	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
527001012657	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
527001012658	major tail tube protein; Provisional; Region: FII; PHA02600
527001012659	major tail sheath protein; Provisional; Region: FI; PHA02560
527001012660	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
527001012661	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
527001012662	DNA-binding interface [nucleotide binding]; DNA binding site
527001012663	type III secretion protein SopE; Provisional; Region: PRK15279
527001012664	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
527001012665	SopE GEF domain; Region: SopE_GEF; pfam07487
527001012666	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
527001012667	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
527001012668	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
527001012669	baseplate assembly protein; Provisional; Region: J; PHA02568
527001012670	baseplate wedge subunit; Provisional; Region: W; PHA02516
527001012671	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
527001012672	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
527001012673	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
527001012674	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
527001012675	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
527001012676	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
527001012677	catalytic residues [active]
527001012678	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
527001012679	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
527001012680	terminase endonuclease subunit; Provisional; Region: M; PHA02537
527001012681	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
527001012682	capsid protein; Provisional; Region: N; PHA02538
527001012683	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
527001012684	terminase ATPase subunit; Provisional; Region: P; PHA02535
527001012685	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
527001012686	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
527001012687	portal vertex protein; Provisional; Region: Q; PHA02536
527001012688	Phage portal protein; Region: Phage_portal; pfam04860
527001012689	Hydrophobic surface binding protein A; Region: HsbA; pfam12296
527001012690	DinI-like family; Region: DinI; pfam06183
527001012691	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
527001012692	DNA adenine methylase (dam); Region: dam; TIGR00571
527001012693	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
527001012694	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
527001012695	active site
527001012696	catalytic site [active]
527001012697	substrate binding site [chemical binding]; other site
527001012698	DksA-like zinc finger domain containing protein; Region: PHA00080
527001012699	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
527001012700	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
527001012701	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
527001012702	Predicted transcriptional regulator [Transcription]; Region: COG2932
527001012703	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
527001012704	integrase; Provisional; Region: int; PHA02601
527001012705	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
527001012706	dimer interface [polypeptide binding]; other site
527001012707	active site
527001012708	catalytic residues [active]
527001012709	Int/Topo IB signature motif; other site
527001012710	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
527001012711	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
527001012712	Catalytic site [active]
527001012713	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
527001012714	hypothetical protein; Provisional; Region: PRK13687
527001012715	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001012716	S-adenosylmethionine binding site [chemical binding]; other site
527001012717	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
527001012718	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001012719	S-adenosylmethionine binding site [chemical binding]; other site
527001012720	Vi polysaccharide export protein VexE; Provisional; Region: PRK15174
527001012721	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
527001012722	TPR motif; other site
527001012723	binding surface
527001012724	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
527001012725	putative acyl-acceptor binding pocket; other site
527001012726	Vi polysaccharide export inner membrane protein VexD; Provisional; Region: PRK15178
527001012727	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
527001012728	Vi polysaccharide export ATP-binding protein VexC; Provisional; Region: PRK15177
527001012729	Walker A/P-loop; other site
527001012730	ATP binding site [chemical binding]; other site
527001012731	Q-loop/lid; other site
527001012732	ABC transporter signature motif; other site
527001012733	Walker B; other site
527001012734	D-loop; other site
527001012735	H-loop/switch region; other site
527001012736	Vi polysaccharide export inner membrane protein VexB; Provisional; Region: PRK15176
527001012737	Vi polysaccharide export protein VexA; Provisional; Region: PRK15175
527001012738	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
527001012739	Vi polysaccharide biosynthesis protein TviE; Provisional; Region: PRK15490
527001012740	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
527001012741	Vi polysaccharide biosynthesis protein TviD; Provisional; Region: PRK15180
527001012742	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
527001012743	UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256
527001012744	NAD binding site [chemical binding]; other site
527001012745	substrate binding site [chemical binding]; other site
527001012746	homodimer interface [polypeptide binding]; other site
527001012747	active site
527001012748	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
527001012749	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
527001012750	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
527001012751	Vi polysaccharide biosynthesis protein TviA; Provisional; Region: PRK15183
527001012752	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
527001012753	Family description; Region: UvrD_C_2; pfam13538
527001012754	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
527001012755	Putative helicase; Region: TraI_2; pfam07514
527001012756	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
527001012757	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
527001012758	active site
527001012759	catalytic residues [active]
527001012760	DNA binding site [nucleotide binding]
527001012761	Int/Topo IB signature motif; other site
527001012762	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
527001012763	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001012764	Coenzyme A binding pocket [chemical binding]; other site
527001012765	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
527001012766	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
527001012767	Integrase; Region: Integrase_1; pfam12835
527001012768	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
527001012769	Bacterial SH3 domain homologues; Region: SH3b; smart00287
527001012770	integrase; Provisional; Region: PRK09692
527001012771	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
527001012772	active site
527001012773	Int/Topo IB signature motif; other site
527001012774	putative transcriptional regulator; Provisional; Region: PRK11640
527001012775	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
527001012776	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
527001012777	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
527001012778	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
527001012779	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
527001012780	DsbD alpha interface [polypeptide binding]; other site
527001012781	catalytic residues [active]
527001012782	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
527001012783	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
527001012784	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
527001012785	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
527001012786	Aspartase; Region: Aspartase; cd01357
527001012787	active sites [active]
527001012788	tetramer interface [polypeptide binding]; other site
527001012789	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
527001012790	putative transporter; Provisional; Region: PRK11021
527001012791	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
527001012792	oligomerisation interface [polypeptide binding]; other site
527001012793	mobile loop; other site
527001012794	roof hairpin; other site
527001012795	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
527001012796	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
527001012797	ring oligomerisation interface [polypeptide binding]; other site
527001012798	ATP/Mg binding site [chemical binding]; other site
527001012799	stacking interactions; other site
527001012800	hinge regions; other site
527001012801	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
527001012802	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
527001012803	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001012804	FeS/SAM binding site; other site
527001012805	elongation factor P; Validated; Region: PRK00529
527001012806	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
527001012807	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
527001012808	RNA binding site [nucleotide binding]; other site
527001012809	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
527001012810	RNA binding site [nucleotide binding]; other site
527001012811	Predicted small secreted protein [Function unknown]; Region: COG5510
527001012812	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
527001012813	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
527001012814	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001012815	DNA binding residues [nucleotide binding]
527001012816	dimerization interface [polypeptide binding]; other site
527001012817	multidrug efflux system protein; Provisional; Region: PRK11431
527001012818	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
527001012819	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
527001012820	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
527001012821	Iron-sulfur protein interface; other site
527001012822	proximal quinone binding site [chemical binding]; other site
527001012823	C-subunit interface; other site
527001012824	distal quinone binding site; other site
527001012825	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
527001012826	D-subunit interface [polypeptide binding]; other site
527001012827	Iron-sulfur protein interface; other site
527001012828	proximal quinone binding site [chemical binding]; other site
527001012829	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
527001012830	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
527001012831	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
527001012832	L-aspartate oxidase; Provisional; Region: PRK06175
527001012833	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
527001012834	poxB regulator PoxA; Provisional; Region: PRK09350
527001012835	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
527001012836	motif 1; other site
527001012837	dimer interface [polypeptide binding]; other site
527001012838	active site
527001012839	motif 2; other site
527001012840	motif 3; other site
527001012841	inner membrane transporter YjeM; Provisional; Region: PRK15238
527001012842	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
527001012843	GTPase RsgA; Reviewed; Region: PRK12288
527001012844	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
527001012845	RNA binding site [nucleotide binding]; other site
527001012846	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
527001012847	GTPase/Zn-binding domain interface [polypeptide binding]; other site
527001012848	GTP/Mg2+ binding site [chemical binding]; other site
527001012849	G4 box; other site
527001012850	G5 box; other site
527001012851	G1 box; other site
527001012852	Switch I region; other site
527001012853	G2 box; other site
527001012854	G3 box; other site
527001012855	Switch II region; other site
527001012856	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
527001012857	catalytic site [active]
527001012858	putative active site [active]
527001012859	putative substrate binding site [chemical binding]; other site
527001012860	dimer interface [polypeptide binding]; other site
527001012861	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
527001012862	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
527001012863	substrate binding pocket [chemical binding]; other site
527001012864	membrane-bound complex binding site; other site
527001012865	hinge residues; other site
527001012866	epoxyqueuosine reductase; Region: TIGR00276
527001012867	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
527001012868	putative carbohydrate kinase; Provisional; Region: PRK10565
527001012869	Uncharacterized conserved protein [Function unknown]; Region: COG0062
527001012870	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
527001012871	putative substrate binding site [chemical binding]; other site
527001012872	putative ATP binding site [chemical binding]; other site
527001012873	ADP-binding protein; Provisional; Region: PRK10646
527001012874	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
527001012875	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
527001012876	active site
527001012877	metal binding site [ion binding]; metal-binding site
527001012878	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
527001012879	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001012880	ATP binding site [chemical binding]; other site
527001012881	Mg2+ binding site [ion binding]; other site
527001012882	G-X-G motif; other site
527001012883	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
527001012884	ATP binding site [chemical binding]; other site
527001012885	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
527001012886	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
527001012887	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
527001012888	bacterial Hfq-like; Region: Hfq; cd01716
527001012889	hexamer interface [polypeptide binding]; other site
527001012890	Sm1 motif; other site
527001012891	RNA binding site [nucleotide binding]; other site
527001012892	Sm2 motif; other site
527001012893	GTPase HflX; Provisional; Region: PRK11058
527001012894	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
527001012895	HflX GTPase family; Region: HflX; cd01878
527001012896	G1 box; other site
527001012897	GTP/Mg2+ binding site [chemical binding]; other site
527001012898	Switch I region; other site
527001012899	G2 box; other site
527001012900	G3 box; other site
527001012901	Switch II region; other site
527001012902	G4 box; other site
527001012903	G5 box; other site
527001012904	FtsH protease regulator HflK; Provisional; Region: PRK10930
527001012905	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
527001012906	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
527001012907	FtsH protease regulator HflC; Provisional; Region: PRK11029
527001012908	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
527001012909	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
527001012910	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
527001012911	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
527001012912	GDP-binding site [chemical binding]; other site
527001012913	ACT binding site; other site
527001012914	IMP binding site; other site
527001012915	Predicted transcriptional regulator [Transcription]; Region: COG1959
527001012916	transcriptional repressor NsrR; Provisional; Region: PRK11014
527001012917	exoribonuclease R; Provisional; Region: PRK11642
527001012918	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
527001012919	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
527001012920	RNB domain; Region: RNB; pfam00773
527001012921	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
527001012922	RNA binding site [nucleotide binding]; other site
527001012923	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
527001012924	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
527001012925	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
527001012926	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
527001012927	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
527001012928	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
527001012929	Predicted membrane protein [Function unknown]; Region: COG3766
527001012930	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
527001012931	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
527001012932	Predicted integral membrane protein [Function unknown]; Region: COG5463
527001012933	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
527001012934	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
527001012935	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
527001012936	FAD binding site [chemical binding]; other site
527001012937	substrate binding site [chemical binding]; other site
527001012938	catalytic residues [active]
527001012939	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
527001012940	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
527001012941	esterase; Provisional; Region: PRK10566
527001012942	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
527001012943	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
527001012944	transcriptional repressor UlaR; Provisional; Region: PRK13509
527001012945	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
527001012946	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
527001012947	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
527001012948	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
527001012949	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
527001012950	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
527001012951	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
527001012952	active site
527001012953	P-loop; other site
527001012954	phosphorylation site [posttranslational modification]
527001012955	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
527001012956	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
527001012957	active site
527001012958	phosphorylation site [posttranslational modification]
527001012959	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
527001012960	active site
527001012961	dimer interface [polypeptide binding]; other site
527001012962	magnesium binding site [ion binding]; other site
527001012963	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
527001012964	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
527001012965	AP (apurinic/apyrimidinic) site pocket; other site
527001012966	DNA interaction; other site
527001012967	Metal-binding active site; metal-binding site
527001012968	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
527001012969	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
527001012970	intersubunit interface [polypeptide binding]; other site
527001012971	active site
527001012972	Zn2+ binding site [ion binding]; other site
527001012973	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
527001012974	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
527001012975	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
527001012976	dimer interface [polypeptide binding]; other site
527001012977	ssDNA binding site [nucleotide binding]; other site
527001012978	tetramer (dimer of dimers) interface [polypeptide binding]; other site
527001012979	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
527001012980	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
527001012981	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
527001012982	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
527001012983	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
527001012984	EamA-like transporter family; Region: EamA; pfam00892
527001012985	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
527001012986	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
527001012987	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
527001012988	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
527001012989	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
527001012990	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
527001012991	DKNYY family; Region: DKNYY; pfam13644
527001012992	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
527001012993	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
527001012994	Hemerythrin-like domain; Region: Hr-like; cd12108
527001012995	Fe binding site [ion binding]; other site
527001012996	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
527001012997	EamA-like transporter family; Region: EamA; pfam00892
527001012998	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
527001012999	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
527001013000	NADP binding site [chemical binding]; other site
527001013001	Predicted transcriptional regulators [Transcription]; Region: COG1733
527001013002	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
527001013003	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
527001013004	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
527001013005	active site
527001013006	metal binding site [ion binding]; metal-binding site
527001013007	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
527001013008	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
527001013009	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
527001013010	active site
527001013011	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
527001013012	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
527001013013	Transposase IS200 like; Region: Y1_Tnp; pfam01797
527001013014	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
527001013015	Domain of unknown function DUF21; Region: DUF21; pfam01595
527001013016	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
527001013017	Transporter associated domain; Region: CorC_HlyC; smart01091
527001013018	methionine sulfoxide reductase A; Provisional; Region: PRK00058
527001013019	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
527001013020	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
527001013021	Surface antigen; Region: Bac_surface_Ag; pfam01103
527001013022	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
527001013023	Family of unknown function (DUF490); Region: DUF490; pfam04357
527001013024	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
527001013025	putative active site pocket [active]
527001013026	dimerization interface [polypeptide binding]; other site
527001013027	putative catalytic residue [active]
527001013028	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001013029	D-galactonate transporter; Region: 2A0114; TIGR00893
527001013030	putative substrate translocation pore; other site
527001013031	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
527001013032	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
527001013033	active site
527001013034	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
527001013035	dimer interface [polypeptide binding]; other site
527001013036	substrate binding site [chemical binding]; other site
527001013037	metal binding sites [ion binding]; metal-binding site
527001013038	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
527001013039	AMP binding site [chemical binding]; other site
527001013040	metal binding site [ion binding]; metal-binding site
527001013041	active site
527001013042	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
527001013043	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
527001013044	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
527001013045	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
527001013046	hypothetical protein; Provisional; Region: PRK05255
527001013047	peptidase PmbA; Provisional; Region: PRK11040
527001013048	cytochrome b562; Provisional; Region: PRK15058
527001013049	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
527001013050	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
527001013051	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
527001013052	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
527001013053	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
527001013054	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
527001013055	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
527001013056	active site
527001013057	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
527001013058	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
527001013059	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
527001013060	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
527001013061	HTH domain; Region: HTH_11; pfam08279
527001013062	Mga helix-turn-helix domain; Region: Mga; pfam05043
527001013063	PRD domain; Region: PRD; pfam00874
527001013064	PRD domain; Region: PRD; pfam00874
527001013065	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
527001013066	active site
527001013067	P-loop; other site
527001013068	phosphorylation site [posttranslational modification]
527001013069	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
527001013070	active site
527001013071	phosphorylation site [posttranslational modification]
527001013072	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
527001013073	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
527001013074	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
527001013075	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001013076	FeS/SAM binding site; other site
527001013077	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
527001013078	ATP cone domain; Region: ATP-cone; pfam03477
527001013079	Class III ribonucleotide reductase; Region: RNR_III; cd01675
527001013080	effector binding site; other site
527001013081	active site
527001013082	Zn binding site [ion binding]; other site
527001013083	glycine loop; other site
527001013084	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
527001013085	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
527001013086	Ca binding site [ion binding]; other site
527001013087	active site
527001013088	catalytic site [active]
527001013089	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
527001013090	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
527001013091	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
527001013092	active site turn [active]
527001013093	phosphorylation site [posttranslational modification]
527001013094	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
527001013095	trehalose repressor; Provisional; Region: treR; PRK09492
527001013096	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001013097	DNA binding site [nucleotide binding]
527001013098	domain linker motif; other site
527001013099	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
527001013100	dimerization interface [polypeptide binding]; other site
527001013101	ligand binding site [chemical binding]; other site
527001013102	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
527001013103	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
527001013104	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
527001013105	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
527001013106	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
527001013107	Soluble P-type ATPase [General function prediction only]; Region: COG4087
527001013108	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
527001013109	Transposase; Region: HTH_Tnp_1; cl17663
527001013110	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
527001013111	homotrimer interaction site [polypeptide binding]; other site
527001013112	putative active site [active]
527001013113	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
527001013114	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
527001013115	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
527001013116	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
527001013117	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
527001013118	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
527001013119	pyrBI operon leader peptide; Provisional; Region: PRK10224
527001013120	Arginine repressor [Transcription]; Region: ArgR; COG1438
527001013121	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
527001013122	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
527001013123	Predicted membrane protein [Function unknown]; Region: COG1288
527001013124	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
527001013125	ornithine carbamoyltransferase; Validated; Region: PRK02102
527001013126	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
527001013127	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
527001013128	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
527001013129	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
527001013130	putative substrate binding site [chemical binding]; other site
527001013131	nucleotide binding site [chemical binding]; other site
527001013132	nucleotide binding site [chemical binding]; other site
527001013133	homodimer interface [polypeptide binding]; other site
527001013134	arginine deiminase; Provisional; Region: PRK01388
527001013135	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
527001013136	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
527001013137	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
527001013138	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
527001013139	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
527001013140	RNase E inhibitor protein; Provisional; Region: PRK11191
527001013141	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
527001013142	active site
527001013143	dinuclear metal binding site [ion binding]; other site
527001013144	dimerization interface [polypeptide binding]; other site
527001013145	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
527001013146	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
527001013147	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001013148	Coenzyme A binding pocket [chemical binding]; other site
527001013149	Predicted membrane protein [Function unknown]; Region: COG4269
527001013150	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
527001013151	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
527001013152	HIGH motif; other site
527001013153	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
527001013154	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
527001013155	active site
527001013156	KMSKS motif; other site
527001013157	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
527001013158	tRNA binding surface [nucleotide binding]; other site
527001013159	anticodon binding site; other site
527001013160	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
527001013161	DNA polymerase III subunit chi; Validated; Region: PRK05728
527001013162	multifunctional aminopeptidase A; Provisional; Region: PRK00913
527001013163	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
527001013164	interface (dimer of trimers) [polypeptide binding]; other site
527001013165	Substrate-binding/catalytic site; other site
527001013166	Zn-binding sites [ion binding]; other site
527001013167	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
527001013168	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
527001013169	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
527001013170	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
527001013171	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
527001013172	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
527001013173	DNA binding site [nucleotide binding]
527001013174	domain linker motif; other site
527001013175	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
527001013176	putative dimerization interface [polypeptide binding]; other site
527001013177	putative ligand binding site [chemical binding]; other site
527001013178	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
527001013179	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
527001013180	gluconate transporter; Region: gntP; TIGR00791
527001013181	fructuronate transporter; Provisional; Region: PRK10034; cl15264
527001013182	integrase; Provisional; Region: PRK09692
527001013183	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
527001013184	active site
527001013185	Int/Topo IB signature motif; other site
527001013186	Catalytic domain of Protein Kinases; Region: PKc; cd00180
527001013187	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
527001013188	active site
527001013189	ATP binding site [chemical binding]; other site
527001013190	substrate binding site [chemical binding]; other site
527001013191	activation loop (A-loop); other site
527001013192	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
527001013193	Catalytic domain of Protein Kinases; Region: PKc; cd00180
527001013194	active site
527001013195	ATP binding site [chemical binding]; other site
527001013196	substrate binding site [chemical binding]; other site
527001013197	activation loop (A-loop); other site
527001013198	Serine/threonine protein phosphatase [Signal transduction mechanisms]; Region: PTC1; COG0631
527001013199	active site
527001013200	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
527001013201	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
527001013202	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
527001013203	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
527001013204	Integrase core domain; Region: rve_2; pfam13333
527001013205	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
527001013206	putative fimbrial chaperone protein SefB; Provisional; Region: PRK15233
527001013207	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001013208	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001013209	outer membrane fimbrial usher protein SefC; Provisional; Region: PRK15235
527001013210	PapC N-terminal domain; Region: PapC_N; pfam13954
527001013211	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
527001013212	PapC C-terminal domain; Region: PapC_C; pfam13953
527001013213	Enterobacteria AfaD invasin protein; Region: AfaD; cl05376
527001013214	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
527001013215	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001013216	FaeA-like protein; Region: FaeA; pfam04703
527001013217	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001013218	DNA binding residues [nucleotide binding]
527001013219	dimerization interface [polypeptide binding]; other site
527001013220	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
527001013221	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
527001013222	catalytic residues [active]
527001013223	hinge region; other site
527001013224	alpha helical domain; other site
527001013225	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
527001013226	SdiA-regulated; Region: SdiA-regulated; cd09971
527001013227	putative active site [active]
527001013228	Transposase; Region: HTH_Tnp_1; pfam01527
527001013229	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
527001013230	Integrase core domain; Region: rve; pfam00665
527001013231	Integrase core domain; Region: rve_3; pfam13683
527001013232	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
527001013233	nucleotide binding region [chemical binding]; other site
527001013234	ATP-binding site [chemical binding]; other site
527001013235	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
527001013236	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only]; Region: COG1205
527001013237	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001013238	ATP binding site [chemical binding]; other site
527001013239	putative Mg++ binding site [ion binding]; other site
527001013240	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
527001013241	HNH endonuclease; Region: HNH_2; pfam13391
527001013242	hypothetical protein; Provisional; Region: PRK12378
527001013243	Methyltransferase domain; Region: Methyltransf_23; pfam13489
527001013244	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001013245	S-adenosylmethionine binding site [chemical binding]; other site
527001013246	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001013247	S-adenosylmethionine binding site [chemical binding]; other site
527001013248	hypothetical protein; Provisional; Region: PRK13687
527001013249	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
527001013250	Uncharacterized conserved protein [Function unknown]; Region: COG3439
527001013251	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
527001013252	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
527001013253	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
527001013254	DNA-binding site [nucleotide binding]; DNA binding site
527001013255	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
527001013256	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
527001013257	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
527001013258	active site
527001013259	HIGH motif; other site
527001013260	dimer interface [polypeptide binding]; other site
527001013261	KMSKS motif; other site
527001013262	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
527001013263	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
527001013264	aspartate racemase; Region: asp_race; TIGR00035
527001013265	cell density-dependent motility repressor; Provisional; Region: PRK10082
527001013266	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
527001013267	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
527001013268	dimerization interface [polypeptide binding]; other site
527001013269	isoaspartyl dipeptidase; Provisional; Region: PRK10657
527001013270	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
527001013271	active site
527001013272	hypothetical protein; Provisional; Region: PRK10519
527001013273	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
527001013274	Nucleoside recognition; Region: Gate; pfam07670
527001013275	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
527001013276	Predicted membrane protein [Function unknown]; Region: COG2733
527001013277	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
527001013278	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
527001013279	putative substrate translocation pore; other site
527001013280	putative transposase; Provisional; Region: PRK09857
527001013281	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
527001013282	potential frameshift: common BLAST hit: gi|194736366|ref|YP_002117442.1| succinate-semialdehyde dehydrogenase (NADP+)
527001013283	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
527001013284	endoribonuclease SymE; Provisional; Region: PRK13605
527001013285	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
527001013286	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
527001013287	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
527001013288	potential frameshift: common BLAST hit: gi|197365232|ref|YP_002144869.1| DNA methylase M, host modification
527001013289	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
527001013290	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
527001013291	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
527001013292	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
527001013293	ATP binding site [chemical binding]; other site
527001013294	putative Mg++ binding site [ion binding]; other site
527001013295	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
527001013296	Mrr N-terminal domain; Region: Mrr_N; pfam14338
527001013297	Restriction endonuclease; Region: Mrr_cat; pfam04471
527001013298	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
527001013299	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
527001013300	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
527001013301	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
527001013302	P-loop, Walker A motif; other site
527001013303	Base recognition motif; other site
527001013304	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
527001013305	Uncharacterized small protein [Function unknown]; Region: COG2879
527001013306	carbon starvation protein A; Provisional; Region: PRK15015
527001013307	Carbon starvation protein CstA; Region: CstA; pfam02554
527001013308	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
527001013309	potential frameshift: common BLAST hit: gi|224586356|ref|YP_002640155.1| methyl-accepting chemotaxis protein I, serine sensor receptor
527001013310	phosphoglycerol transferase I; Provisional; Region: PRK03776
527001013311	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
527001013312	hypothetical protein; Provisional; Region: PRK11667
527001013313	DNA replication protein DnaC; Validated; Region: PRK07952
527001013314	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
527001013315	Walker A motif; other site
527001013316	ATP binding site [chemical binding]; other site
527001013317	Walker B motif; other site
527001013318	primosomal protein DnaI; Provisional; Region: PRK02854
527001013319	hypothetical protein; Provisional; Region: PRK09917
527001013320	Uncharacterized conserved protein [Function unknown]; Region: COG2966
527001013321	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
527001013322	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
527001013323	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001013324	DNA binding residues [nucleotide binding]
527001013325	dimerization interface [polypeptide binding]; other site
527001013326	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
527001013327	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
527001013328	DNA binding residues [nucleotide binding]
527001013329	dimerization interface [polypeptide binding]; other site
527001013330	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
527001013331	putative deacylase active site [active]
527001013332	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
527001013333	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
527001013334	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
527001013335	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
527001013336	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
527001013337	metal binding site [ion binding]; metal-binding site
527001013338	active site
527001013339	I-site; other site
527001013340	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
527001013341	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
527001013342	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
527001013343	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
527001013344	S-adenosylmethionine binding site [chemical binding]; other site
527001013345	DNA polymerase III subunit psi; Validated; Region: PRK06856
527001013346	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
527001013347	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
527001013348	Coenzyme A binding pocket [chemical binding]; other site
527001013349	dUMP phosphatase; Provisional; Region: PRK09449
527001013350	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001013351	motif II; other site
527001013352	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
527001013353	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
527001013354	G1 box; other site
527001013355	putative GEF interaction site [polypeptide binding]; other site
527001013356	GTP/Mg2+ binding site [chemical binding]; other site
527001013357	Switch I region; other site
527001013358	G2 box; other site
527001013359	G3 box; other site
527001013360	Switch II region; other site
527001013361	G4 box; other site
527001013362	G5 box; other site
527001013363	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
527001013364	periplasmic protein; Provisional; Region: PRK10568
527001013365	BON domain; Region: BON; pfam04972
527001013366	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
527001013367	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
527001013368	active site
527001013369	nucleophile elbow; other site
527001013370	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
527001013371	active site
527001013372	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
527001013373	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
527001013374	FeS/SAM binding site; other site
527001013375	hypothetical protein; Provisional; Region: PRK10977
527001013376	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
527001013377	intersubunit interface [polypeptide binding]; other site
527001013378	active site
527001013379	catalytic residue [active]
527001013380	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
527001013381	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
527001013382	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
527001013383	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
527001013384	phosphopentomutase; Provisional; Region: PRK05362
527001013385	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
527001013386	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
527001013387	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
527001013388	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
527001013389	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
527001013390	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
527001013391	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
527001013392	hypothetical protein; Provisional; Region: PRK11246
527001013393	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
527001013394	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
527001013395	motif II; other site
527001013396	DNA repair protein RadA; Region: sms; TIGR00416
527001013397	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
527001013398	Walker A motif/ATP binding site; other site
527001013399	ATP binding site [chemical binding]; other site
527001013400	Walker B motif; other site
527001013401	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
527001013402	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
527001013403	non-specific DNA binding site [nucleotide binding]; other site
527001013404	salt bridge; other site
527001013405	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
527001013406	sequence-specific DNA binding site [nucleotide binding]; other site
527001013407	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
527001013408	active site
527001013409	(T/H)XGH motif; other site
527001013410	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
527001013411	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
527001013412	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
527001013413	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
527001013414	ABC transporter; Region: ABC_tran_2; pfam12848
527001013415	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
527001013416	lytic murein transglycosylase; Provisional; Region: PRK11619
527001013417	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
527001013418	N-acetyl-D-glucosamine binding site [chemical binding]; other site
527001013419	catalytic residue [active]
527001013420	Trp operon repressor; Provisional; Region: PRK01381
527001013421	Protein of unknown function DUF84; Region: NTPase_I-T; cl00866
527001013422	Protein of unknown function DUF84; Region: NTPase_I-T; cl00866
527001013423	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
527001013424	catalytic core [active]
527001013425	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
527001013426	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
527001013427	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
527001013428	hypothetical protein; Provisional; Region: PRK10756
527001013429	CreA protein; Region: CreA; pfam05981
527001013430	DNA-binding response regulator CreB; Provisional; Region: PRK11083
527001013431	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001013432	active site
527001013433	phosphorylation site [posttranslational modification]
527001013434	intermolecular recognition site; other site
527001013435	dimerization interface [polypeptide binding]; other site
527001013436	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001013437	DNA binding site [nucleotide binding]
527001013438	sensory histidine kinase CreC; Provisional; Region: PRK11100
527001013439	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
527001013440	dimerization interface [polypeptide binding]; other site
527001013441	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
527001013442	dimer interface [polypeptide binding]; other site
527001013443	phosphorylation site [posttranslational modification]
527001013444	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
527001013445	ATP binding site [chemical binding]; other site
527001013446	Mg2+ binding site [ion binding]; other site
527001013447	G-X-G motif; other site
527001013448	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
527001013449	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
527001013450	putative fimbrial protein SthD; Provisional; Region: PRK15293
527001013451	PapC N-terminal domain; Region: PapC_N; pfam13954
527001013452	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
527001013453	PapC C-terminal domain; Region: PapC_C; pfam13953
527001013454	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
527001013455	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
527001013456	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
527001013457	putative fimbrial protein SthA; Provisional; Region: PRK15296
527001013458	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
527001013459	Helix-turn-helix domain; Region: HTH_36; pfam13730
527001013460	two-component response regulator; Provisional; Region: PRK11173
527001013461	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
527001013462	active site
527001013463	phosphorylation site [posttranslational modification]
527001013464	intermolecular recognition site; other site
527001013465	dimerization interface [polypeptide binding]; other site
527001013466	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
527001013467	DNA binding site [nucleotide binding]
527001013468	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
527001013469	putative RNA methyltransferase; Provisional; Region: PRK10433