-- dump date   	20140620_054856
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
209261000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
209261000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
209261000003	putative catalytic residues [active]
209261000004	putative nucleotide binding site [chemical binding]; other site
209261000005	putative aspartate binding site [chemical binding]; other site
209261000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
209261000007	dimer interface [polypeptide binding]; other site
209261000008	putative threonine allosteric regulatory site; other site
209261000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
209261000010	putative threonine allosteric regulatory site; other site
209261000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
209261000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
209261000013	homoserine kinase; Provisional; Region: PRK01212
209261000014	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
209261000015	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
209261000016	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
209261000017	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261000018	catalytic residue [active]
209261000019	hypothetical protein; Validated; Region: PRK02101
209261000020	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
209261000021	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
209261000022	transaldolase-like protein; Provisional; Region: PTZ00411
209261000023	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
209261000024	active site
209261000025	dimer interface [polypeptide binding]; other site
209261000026	catalytic residue [active]
209261000027	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
209261000028	MPT binding site; other site
209261000029	trimer interface [polypeptide binding]; other site
209261000030	hypothetical protein; Provisional; Region: PRK10659
209261000031	hypothetical protein; Provisional; Region: PRK10236
209261000032	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
209261000033	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
209261000034	Protein of unknown function (DUF2541); Region: DUF2541; pfam10807
209261000035	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
209261000036	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
209261000037	nucleotide binding site [chemical binding]; other site
209261000038	chaperone protein DnaJ; Provisional; Region: PRK10767
209261000039	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
209261000040	HSP70 interaction site [polypeptide binding]; other site
209261000041	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
209261000042	substrate binding site [polypeptide binding]; other site
209261000043	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
209261000044	Zn binding sites [ion binding]; other site
209261000045	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
209261000046	dimer interface [polypeptide binding]; other site
209261000047	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261000048	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261000049	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
209261000050	dimerization interface [polypeptide binding]; other site
209261000051	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
209261000052	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
209261000053	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
209261000054	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
209261000055	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
209261000056	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
209261000057	active site
209261000058	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
209261000059	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
209261000060	aromatic chitin/cellulose binding site residues [chemical binding]; other site
209261000061	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
209261000062	Helix-turn-helix domain; Region: HTH_36; pfam13730
209261000063	fimbrial protein BcfA; Provisional; Region: PRK15187
209261000064	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
209261000065	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261000066	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261000067	fimbrial protein BcfD; Provisional; Region: PRK15189
209261000068	fimbrial protein BcfE; Provisional; Region: PRK15190
209261000069	fimbrial protein BcfF; Provisional; Region: PRK15191
209261000070	fimbrial chaperone BcfG; Provisional; Region: PRK15192
209261000071	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261000072	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261000073	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
209261000074	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
209261000075	catalytic residues [active]
209261000076	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
209261000077	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261000078	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261000079	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
209261000080	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
209261000081	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
209261000082	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
209261000083	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
209261000084	active site
209261000085	metal binding site [ion binding]; metal-binding site
209261000086	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
209261000087	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
209261000088	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
209261000089	Sulfatase; Region: Sulfatase; pfam00884
209261000090	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
209261000091	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261000092	FeS/SAM binding site; other site
209261000093	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
209261000094	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
209261000095	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
209261000096	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
209261000097	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261000098	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
209261000099	putative dimerization interface [polypeptide binding]; other site
209261000100	putative alpha-glucosidase; Provisional; Region: PRK10658
209261000101	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
209261000102	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
209261000103	putative active site [active]
209261000104	putative catalytic site [active]
209261000105	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
209261000106	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
209261000107	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
209261000108	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
209261000109	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
209261000110	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
209261000111	active site
209261000112	Riboflavin kinase; Region: Flavokinase; smart00904
209261000113	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
209261000114	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
209261000115	active site
209261000116	HIGH motif; other site
209261000117	nucleotide binding site [chemical binding]; other site
209261000118	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
209261000119	active site
209261000120	KMSKS motif; other site
209261000121	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
209261000122	tRNA binding surface [nucleotide binding]; other site
209261000123	anticodon binding site; other site
209261000124	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
209261000125	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
209261000126	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
209261000127	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
209261000128	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
209261000129	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
209261000130	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
209261000131	active site
209261000132	tetramer interface [polypeptide binding]; other site
209261000133	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
209261000134	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261000135	active site
209261000136	phosphorylation site [posttranslational modification]
209261000137	intermolecular recognition site; other site
209261000138	dimerization interface [polypeptide binding]; other site
209261000139	Transcriptional regulator; Region: CitT; pfam12431
209261000140	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
209261000141	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
209261000142	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261000143	ATP binding site [chemical binding]; other site
209261000144	Mg2+ binding site [ion binding]; other site
209261000145	G-X-G motif; other site
209261000146	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
209261000147	oxaloacetate decarboxylase; Provisional; Region: PRK14040
209261000148	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
209261000149	active site
209261000150	catalytic residues [active]
209261000151	metal binding site [ion binding]; metal-binding site
209261000152	homodimer binding site [polypeptide binding]; other site
209261000153	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
209261000154	carboxyltransferase (CT) interaction site; other site
209261000155	biotinylation site [posttranslational modification]; other site
209261000156	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
209261000157	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
209261000158	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
209261000159	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
209261000160	putative active site [active]
209261000161	(T/H)XGH motif; other site
209261000162	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
209261000163	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
209261000164	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
209261000165	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
209261000166	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
209261000167	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
209261000168	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
209261000169	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
209261000170	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
209261000171	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
209261000172	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
209261000173	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
209261000174	catalytic site [active]
209261000175	subunit interface [polypeptide binding]; other site
209261000176	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
209261000177	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
209261000178	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
209261000179	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
209261000180	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
209261000181	ATP-grasp domain; Region: ATP-grasp_4; cl17255
209261000182	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
209261000183	IMP binding site; other site
209261000184	dimer interface [polypeptide binding]; other site
209261000185	interdomain contacts; other site
209261000186	partial ornithine binding site; other site
209261000187	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
209261000188	carnitine operon protein CaiE; Provisional; Region: PRK13627
209261000189	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
209261000190	putative trimer interface [polypeptide binding]; other site
209261000191	putative metal binding site [ion binding]; other site
209261000192	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
209261000193	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
209261000194	substrate binding site [chemical binding]; other site
209261000195	oxyanion hole (OAH) forming residues; other site
209261000196	trimer interface [polypeptide binding]; other site
209261000197	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
209261000198	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
209261000199	acyl-activating enzyme (AAE) consensus motif; other site
209261000200	putative AMP binding site [chemical binding]; other site
209261000201	putative active site [active]
209261000202	putative CoA binding site [chemical binding]; other site
209261000203	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
209261000204	CoA-transferase family III; Region: CoA_transf_3; pfam02515
209261000205	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
209261000206	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
209261000207	active site
209261000208	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
209261000209	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
209261000210	Ligand binding site [chemical binding]; other site
209261000211	Electron transfer flavoprotein domain; Region: ETF; pfam01012
209261000212	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
209261000213	Electron transfer flavoprotein domain; Region: ETF; smart00893
209261000214	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
209261000215	putative oxidoreductase FixC; Provisional; Region: PRK10157
209261000216	ferredoxin-like protein FixX; Provisional; Region: PRK15449
209261000217	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261000218	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
209261000219	putative substrate translocation pore; other site
209261000220	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
209261000221	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
209261000222	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
209261000223	Sulfatase; Region: Sulfatase; cl17466
209261000224	Sulfatase; Region: Sulfatase; cl17466
209261000225	Sulfatase; Region: Sulfatase; cl17466
209261000226	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
209261000227	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
209261000228	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
209261000229	TrkA-N domain; Region: TrkA_N; pfam02254
209261000230	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
209261000231	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
209261000232	folate binding site [chemical binding]; other site
209261000233	NADP+ binding site [chemical binding]; other site
209261000234	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
209261000235	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
209261000236	active site
209261000237	metal binding site [ion binding]; metal-binding site
209261000238	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
209261000239	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
209261000240	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
209261000241	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
209261000242	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
209261000243	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
209261000244	SurA N-terminal domain; Region: SurA_N; pfam09312
209261000245	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
209261000246	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
209261000247	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
209261000248	OstA-like protein; Region: OstA; pfam03968
209261000249	Organic solvent tolerance protein; Region: OstA_C; pfam04453
209261000250	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
209261000251	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
209261000252	putative metal binding site [ion binding]; other site
209261000253	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
209261000254	HSP70 interaction site [polypeptide binding]; other site
209261000255	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
209261000256	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
209261000257	active site
209261000258	ATP-dependent helicase HepA; Validated; Region: PRK04914
209261000259	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261000260	ATP binding site [chemical binding]; other site
209261000261	putative Mg++ binding site [ion binding]; other site
209261000262	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261000263	nucleotide binding region [chemical binding]; other site
209261000264	ATP-binding site [chemical binding]; other site
209261000265	DNA polymerase II; Reviewed; Region: PRK05762
209261000266	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
209261000267	active site
209261000268	catalytic site [active]
209261000269	substrate binding site [chemical binding]; other site
209261000270	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
209261000271	active site
209261000272	metal-binding site
209261000273	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261000274	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
209261000275	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
209261000276	Probable transposase; Region: OrfB_IS605; pfam01385
209261000277	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
209261000278	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
209261000279	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
209261000280	intersubunit interface [polypeptide binding]; other site
209261000281	active site
209261000282	Zn2+ binding site [ion binding]; other site
209261000283	L-arabinose isomerase; Provisional; Region: PRK02929
209261000284	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
209261000285	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
209261000286	trimer interface [polypeptide binding]; other site
209261000287	putative substrate binding site [chemical binding]; other site
209261000288	putative metal binding site [ion binding]; other site
209261000289	ribulokinase; Provisional; Region: PRK04123
209261000290	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
209261000291	N- and C-terminal domain interface [polypeptide binding]; other site
209261000292	active site
209261000293	MgATP binding site [chemical binding]; other site
209261000294	catalytic site [active]
209261000295	metal binding site [ion binding]; metal-binding site
209261000296	carbohydrate binding site [chemical binding]; other site
209261000297	homodimer interface [polypeptide binding]; other site
209261000298	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
209261000299	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
209261000300	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261000301	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261000302	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
209261000303	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
209261000304	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
209261000305	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
209261000306	Walker A/P-loop; other site
209261000307	ATP binding site [chemical binding]; other site
209261000308	Q-loop/lid; other site
209261000309	ABC transporter signature motif; other site
209261000310	Walker B; other site
209261000311	D-loop; other site
209261000312	H-loop/switch region; other site
209261000313	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
209261000314	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261000315	dimer interface [polypeptide binding]; other site
209261000316	conserved gate region; other site
209261000317	putative PBP binding loops; other site
209261000318	ABC-ATPase subunit interface; other site
209261000319	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261000320	dimer interface [polypeptide binding]; other site
209261000321	conserved gate region; other site
209261000322	putative PBP binding loops; other site
209261000323	ABC-ATPase subunit interface; other site
209261000324	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
209261000325	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
209261000326	transcriptional regulator SgrR; Provisional; Region: PRK13626
209261000327	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
209261000328	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
209261000329	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
209261000330	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
209261000331	substrate binding site [chemical binding]; other site
209261000332	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
209261000333	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
209261000334	substrate binding site [chemical binding]; other site
209261000335	ligand binding site [chemical binding]; other site
209261000336	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
209261000337	tartrate dehydrogenase; Region: TTC; TIGR02089
209261000338	2-isopropylmalate synthase; Validated; Region: PRK00915
209261000339	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
209261000340	active site
209261000341	catalytic residues [active]
209261000342	metal binding site [ion binding]; metal-binding site
209261000343	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
209261000344	leu operon leader peptide; Provisional; Region: PRK14744
209261000345	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
209261000346	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261000347	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
209261000348	putative substrate binding pocket [chemical binding]; other site
209261000349	putative dimerization interface [polypeptide binding]; other site
209261000350	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
209261000351	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
209261000352	PYR/PP interface [polypeptide binding]; other site
209261000353	dimer interface [polypeptide binding]; other site
209261000354	TPP binding site [chemical binding]; other site
209261000355	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
209261000356	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
209261000357	TPP-binding site [chemical binding]; other site
209261000358	dimer interface [polypeptide binding]; other site
209261000359	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
209261000360	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
209261000361	putative valine binding site [chemical binding]; other site
209261000362	dimer interface [polypeptide binding]; other site
209261000363	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
209261000364	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
209261000365	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261000366	DNA binding site [nucleotide binding]
209261000367	domain linker motif; other site
209261000368	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
209261000369	dimerization interface [polypeptide binding]; other site
209261000370	ligand binding site [chemical binding]; other site
209261000371	mraZ protein; Region: TIGR00242
209261000372	MraZ protein; Region: MraZ; pfam02381
209261000373	MraZ protein; Region: MraZ; pfam02381
209261000374	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
209261000375	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
209261000376	cell division protein FtsL; Provisional; Region: PRK10772
209261000377	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
209261000378	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
209261000379	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
209261000380	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
209261000381	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
209261000382	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
209261000383	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
209261000384	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
209261000385	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
209261000386	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
209261000387	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
209261000388	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
209261000389	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
209261000390	Mg++ binding site [ion binding]; other site
209261000391	putative catalytic motif [active]
209261000392	putative substrate binding site [chemical binding]; other site
209261000393	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
209261000394	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
209261000395	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
209261000396	cell division protein FtsW; Provisional; Region: PRK10774
209261000397	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
209261000398	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
209261000399	active site
209261000400	homodimer interface [polypeptide binding]; other site
209261000401	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
209261000402	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
209261000403	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
209261000404	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
209261000405	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
209261000406	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
209261000407	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
209261000408	cell division protein FtsQ; Provisional; Region: PRK10775
209261000409	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
209261000410	Cell division protein FtsQ; Region: FtsQ; pfam03799
209261000411	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
209261000412	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
209261000413	Cell division protein FtsA; Region: FtsA; pfam14450
209261000414	cell division protein FtsZ; Validated; Region: PRK09330
209261000415	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
209261000416	nucleotide binding site [chemical binding]; other site
209261000417	SulA interaction site; other site
209261000418	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
209261000419	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
209261000420	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
209261000421	SecA regulator SecM; Provisional; Region: PRK02943
209261000422	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
209261000423	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
209261000424	SEC-C motif; Region: SEC-C; pfam02810
209261000425	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
209261000426	active site
209261000427	8-oxo-dGMP binding site [chemical binding]; other site
209261000428	nudix motif; other site
209261000429	metal binding site [ion binding]; metal-binding site
209261000430	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
209261000431	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
209261000432	active site
209261000433	catalytic tetrad [active]
209261000434	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261000435	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261000436	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
209261000437	putative effector binding pocket; other site
209261000438	putative dimerization interface [polypeptide binding]; other site
209261000439	DNA gyrase inhibitor; Reviewed; Region: PRK00418
209261000440	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
209261000441	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
209261000442	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
209261000443	CoA-binding site [chemical binding]; other site
209261000444	ATP-binding [chemical binding]; other site
209261000445	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
209261000446	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
209261000447	active site
209261000448	type IV pilin biogenesis protein; Provisional; Region: PRK10573
209261000449	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
209261000450	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
209261000451	hypothetical protein; Provisional; Region: PRK10436
209261000452	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
209261000453	Walker A motif; other site
209261000454	ATP binding site [chemical binding]; other site
209261000455	Walker B motif; other site
209261000456	putative major pilin subunit; Provisional; Region: PRK10574
209261000457	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
209261000458	Pilin (bacterial filament); Region: Pilin; pfam00114
209261000459	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
209261000460	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
209261000461	dimerization interface [polypeptide binding]; other site
209261000462	active site
209261000463	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
209261000464	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
209261000465	amidase catalytic site [active]
209261000466	Zn binding residues [ion binding]; other site
209261000467	substrate binding site [chemical binding]; other site
209261000468	regulatory protein AmpE; Provisional; Region: PRK10987
209261000469	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
209261000470	active site
209261000471	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
209261000472	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261000473	putative substrate translocation pore; other site
209261000474	aromatic amino acid transporter; Provisional; Region: PRK10238
209261000475	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
209261000476	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261000477	DNA-binding site [nucleotide binding]; DNA binding site
209261000478	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
209261000479	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
209261000480	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
209261000481	dimer interface [polypeptide binding]; other site
209261000482	TPP-binding site [chemical binding]; other site
209261000483	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
209261000484	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
209261000485	E3 interaction surface; other site
209261000486	lipoyl attachment site [posttranslational modification]; other site
209261000487	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
209261000488	E3 interaction surface; other site
209261000489	lipoyl attachment site [posttranslational modification]; other site
209261000490	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
209261000491	E3 interaction surface; other site
209261000492	lipoyl attachment site [posttranslational modification]; other site
209261000493	e3 binding domain; Region: E3_binding; pfam02817
209261000494	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
209261000495	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
209261000496	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
209261000497	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261000498	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
209261000499	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
209261000500	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
209261000501	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
209261000502	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
209261000503	substrate binding site [chemical binding]; other site
209261000504	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
209261000505	substrate binding site [chemical binding]; other site
209261000506	ligand binding site [chemical binding]; other site
209261000507	hypothetical protein; Provisional; Region: PRK05248
209261000508	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
209261000509	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
209261000510	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
209261000511	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
209261000512	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
209261000513	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
209261000514	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261000515	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
209261000516	spermidine synthase; Provisional; Region: PRK00811
209261000517	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261000518	S-adenosylmethionine binding site [chemical binding]; other site
209261000519	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
209261000520	multicopper oxidase; Provisional; Region: PRK10965
209261000521	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
209261000522	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
209261000523	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
209261000524	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
209261000525	Trp docking motif [polypeptide binding]; other site
209261000526	putative active site [active]
209261000527	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
209261000528	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
209261000529	active site
209261000530	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
209261000531	active site clefts [active]
209261000532	zinc binding site [ion binding]; other site
209261000533	dimer interface [polypeptide binding]; other site
209261000534	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
209261000535	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
209261000536	Walker A/P-loop; other site
209261000537	ATP binding site [chemical binding]; other site
209261000538	Q-loop/lid; other site
209261000539	ABC transporter signature motif; other site
209261000540	Walker B; other site
209261000541	D-loop; other site
209261000542	H-loop/switch region; other site
209261000543	inner membrane transport permease; Provisional; Region: PRK15066
209261000544	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
209261000545	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
209261000546	active pocket/dimerization site; other site
209261000547	active site
209261000548	phosphorylation site [posttranslational modification]
209261000549	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
209261000550	putative active site [active]
209261000551	putative metal binding site [ion binding]; other site
209261000552	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
209261000553	tetramerization interface [polypeptide binding]; other site
209261000554	active site
209261000555	Pantoate-beta-alanine ligase; Region: PanC; cd00560
209261000556	pantoate--beta-alanine ligase; Region: panC; TIGR00018
209261000557	active site
209261000558	ATP-binding site [chemical binding]; other site
209261000559	pantoate-binding site; other site
209261000560	HXXH motif; other site
209261000561	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
209261000562	oligomerization interface [polypeptide binding]; other site
209261000563	active site
209261000564	metal binding site [ion binding]; metal-binding site
209261000565	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
209261000566	putative fimbrial protein StaF; Provisional; Region: PRK15262
209261000567	putative fimbrial protein StaE; Provisional; Region: PRK15263
209261000568	putative fimbrial protein StaD; Provisional; Region: PRK15241
209261000569	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
209261000570	PapC N-terminal domain; Region: PapC_N; pfam13954
209261000571	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
209261000572	PapC C-terminal domain; Region: PapC_C; pfam13953
209261000573	putative chaperone protein EcpD; Provisional; Region: PRK09926
209261000574	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261000575	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261000576	putative fimbrial protein StaA; Provisional; Region: PRK15239
209261000577	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
209261000578	catalytic center binding site [active]
209261000579	ATP binding site [chemical binding]; other site
209261000580	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
209261000581	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
209261000582	active site
209261000583	NTP binding site [chemical binding]; other site
209261000584	metal binding triad [ion binding]; metal-binding site
209261000585	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
209261000586	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
209261000587	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
209261000588	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
209261000589	active site
209261000590	nucleotide binding site [chemical binding]; other site
209261000591	HIGH motif; other site
209261000592	KMSKS motif; other site
209261000593	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
209261000594	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
209261000595	2'-5' RNA ligase; Provisional; Region: PRK15124
209261000596	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
209261000597	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
209261000598	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
209261000599	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261000600	ATP binding site [chemical binding]; other site
209261000601	putative Mg++ binding site [ion binding]; other site
209261000602	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261000603	nucleotide binding region [chemical binding]; other site
209261000604	ATP-binding site [chemical binding]; other site
209261000605	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
209261000606	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
209261000607	Transglycosylase; Region: Transgly; pfam00912
209261000608	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
209261000609	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
209261000610	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
209261000611	Walker A/P-loop; other site
209261000612	ATP binding site [chemical binding]; other site
209261000613	Q-loop/lid; other site
209261000614	ABC transporter signature motif; other site
209261000615	Walker B; other site
209261000616	D-loop; other site
209261000617	H-loop/switch region; other site
209261000618	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
209261000619	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
209261000620	siderophore binding site; other site
209261000621	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
209261000622	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
209261000623	ABC-ATPase subunit  interface; other site
209261000624	dimer interface [polypeptide binding]; other site
209261000625	putative PBP binding regions; other site
209261000626	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
209261000627	ABC-ATPase subunit  interface; other site
209261000628	dimer interface [polypeptide binding]; other site
209261000629	putative PBP binding regions; other site
209261000630	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
209261000631	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
209261000632	inhibitor-cofactor binding pocket; inhibition site
209261000633	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261000634	catalytic residue [active]
209261000635	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
209261000636	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
209261000637	Cl- selectivity filter; other site
209261000638	Cl- binding residues [ion binding]; other site
209261000639	pore gating glutamate residue; other site
209261000640	dimer interface [polypeptide binding]; other site
209261000641	H+/Cl- coupling transport residue; other site
209261000642	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
209261000643	hypothetical protein; Provisional; Region: PRK10578
209261000644	UPF0126 domain; Region: UPF0126; pfam03458
209261000645	UPF0126 domain; Region: UPF0126; pfam03458
209261000646	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
209261000647	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
209261000648	cobalamin binding residues [chemical binding]; other site
209261000649	putative BtuC binding residues; other site
209261000650	dimer interface [polypeptide binding]; other site
209261000651	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
209261000652	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
209261000653	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
209261000654	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
209261000655	Zn2+ binding site [ion binding]; other site
209261000656	Mg2+ binding site [ion binding]; other site
209261000657	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
209261000658	serine endoprotease; Provisional; Region: PRK10942
209261000659	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
209261000660	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
209261000661	protein binding site [polypeptide binding]; other site
209261000662	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
209261000663	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
209261000664	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
209261000665	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
209261000666	hypothetical protein; Provisional; Region: PRK13677
209261000667	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
209261000668	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
209261000669	trimer interface [polypeptide binding]; other site
209261000670	active site
209261000671	substrate binding site [chemical binding]; other site
209261000672	CoA binding site [chemical binding]; other site
209261000673	PII uridylyl-transferase; Provisional; Region: PRK05007
209261000674	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
209261000675	metal binding triad; other site
209261000676	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
209261000677	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
209261000678	Zn2+ binding site [ion binding]; other site
209261000679	Mg2+ binding site [ion binding]; other site
209261000680	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
209261000681	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
209261000682	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
209261000683	active site
209261000684	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
209261000685	rRNA interaction site [nucleotide binding]; other site
209261000686	S8 interaction site; other site
209261000687	putative laminin-1 binding site; other site
209261000688	elongation factor Ts; Provisional; Region: tsf; PRK09377
209261000689	UBA/TS-N domain; Region: UBA; pfam00627
209261000690	Elongation factor TS; Region: EF_TS; pfam00889
209261000691	Elongation factor TS; Region: EF_TS; pfam00889
209261000692	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
209261000693	putative nucleotide binding site [chemical binding]; other site
209261000694	uridine monophosphate binding site [chemical binding]; other site
209261000695	homohexameric interface [polypeptide binding]; other site
209261000696	ribosome recycling factor; Reviewed; Region: frr; PRK00083
209261000697	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
209261000698	hinge region; other site
209261000699	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
209261000700	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
209261000701	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
209261000702	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
209261000703	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
209261000704	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
209261000705	catalytic residue [active]
209261000706	putative FPP diphosphate  binding site; other site
209261000707	putative FPP binding hydrophobic cleft; other site
209261000708	dimer interface [polypeptide binding]; other site
209261000709	putative IPP diphosphate binding site; other site
209261000710	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
209261000711	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
209261000712	zinc metallopeptidase RseP; Provisional; Region: PRK10779
209261000713	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
209261000714	active site
209261000715	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
209261000716	protein binding site [polypeptide binding]; other site
209261000717	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
209261000718	protein binding site [polypeptide binding]; other site
209261000719	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
209261000720	putative substrate binding region [chemical binding]; other site
209261000721	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
209261000722	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
209261000723	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
209261000724	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
209261000725	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
209261000726	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
209261000727	Surface antigen; Region: Bac_surface_Ag; pfam01103
209261000728	periplasmic chaperone; Provisional; Region: PRK10780
209261000729	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
209261000730	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
209261000731	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
209261000732	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
209261000733	trimer interface [polypeptide binding]; other site
209261000734	active site
209261000735	UDP-GlcNAc binding site [chemical binding]; other site
209261000736	lipid binding site [chemical binding]; lipid-binding site
209261000737	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
209261000738	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
209261000739	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
209261000740	active site
209261000741	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
209261000742	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
209261000743	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
209261000744	RNA/DNA hybrid binding site [nucleotide binding]; other site
209261000745	active site
209261000746	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
209261000747	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
209261000748	putative active site [active]
209261000749	putative PHP Thumb interface [polypeptide binding]; other site
209261000750	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
209261000751	generic binding surface II; other site
209261000752	generic binding surface I; other site
209261000753	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
209261000754	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
209261000755	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261000756	lysine decarboxylase LdcC; Provisional; Region: PRK15399
209261000757	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
209261000758	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
209261000759	homodimer interface [polypeptide binding]; other site
209261000760	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261000761	catalytic residue [active]
209261000762	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
209261000763	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
209261000764	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
209261000765	putative metal binding site [ion binding]; other site
209261000766	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
209261000767	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
209261000768	Ligand Binding Site [chemical binding]; other site
209261000769	TilS substrate binding domain; Region: TilS; pfam09179
209261000770	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
209261000771	Rho-binding antiterminator; Provisional; Region: PRK11625
209261000772	hypothetical protein; Provisional; Region: PRK04964
209261000773	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
209261000774	hypothetical protein; Provisional; Region: PRK09256
209261000775	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
209261000776	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
209261000777	NlpE N-terminal domain; Region: NlpE; pfam04170
209261000778	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261000779	prolyl-tRNA synthetase; Provisional; Region: PRK09194
209261000780	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
209261000781	dimer interface [polypeptide binding]; other site
209261000782	motif 1; other site
209261000783	active site
209261000784	motif 2; other site
209261000785	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
209261000786	putative deacylase active site [active]
209261000787	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
209261000788	active site
209261000789	motif 3; other site
209261000790	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
209261000791	anticodon binding site; other site
209261000792	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
209261000793	homodimer interaction site [polypeptide binding]; other site
209261000794	cofactor binding site; other site
209261000795	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
209261000796	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
209261000797	lipoprotein, YaeC family; Region: TIGR00363
209261000798	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261000799	dimer interface [polypeptide binding]; other site
209261000800	conserved gate region; other site
209261000801	ABC-ATPase subunit interface; other site
209261000802	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
209261000803	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
209261000804	Walker A/P-loop; other site
209261000805	ATP binding site [chemical binding]; other site
209261000806	Q-loop/lid; other site
209261000807	ABC transporter signature motif; other site
209261000808	Walker B; other site
209261000809	D-loop; other site
209261000810	H-loop/switch region; other site
209261000811	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
209261000812	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
209261000813	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261000814	active site
209261000815	motif I; other site
209261000816	motif II; other site
209261000817	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
209261000818	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
209261000819	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261000820	putative substrate translocation pore; other site
209261000821	lipoprotein; Provisional; Region: PRK10759
209261000822	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
209261000823	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
209261000824	domain interface [polypeptide binding]; other site
209261000825	putative active site [active]
209261000826	catalytic site [active]
209261000827	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
209261000828	domain interface [polypeptide binding]; other site
209261000829	putative active site [active]
209261000830	catalytic site [active]
209261000831	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
209261000832	CoA binding domain; Region: CoA_binding_2; pfam13380
209261000833	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
209261000834	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
209261000835	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
209261000836	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261000837	Coenzyme A binding pocket [chemical binding]; other site
209261000838	Uncharacterized conserved protein [Function unknown]; Region: COG3148
209261000839	thioredoxin 2; Provisional; Region: PRK10996
209261000840	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
209261000841	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
209261000842	catalytic residues [active]
209261000843	putative methyltransferase; Provisional; Region: PRK10864
209261000844	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
209261000845	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
209261000846	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
209261000847	ligand binding site [chemical binding]; other site
209261000848	active site
209261000849	UGI interface [polypeptide binding]; other site
209261000850	catalytic site [active]
209261000851	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
209261000852	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
209261000853	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
209261000854	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
209261000855	ATP binding site [chemical binding]; other site
209261000856	Mg++ binding site [ion binding]; other site
209261000857	motif III; other site
209261000858	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261000859	nucleotide binding region [chemical binding]; other site
209261000860	ATP-binding site [chemical binding]; other site
209261000861	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
209261000862	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261000863	S-adenosylmethionine binding site [chemical binding]; other site
209261000864	L-aspartate oxidase; Provisional; Region: PRK09077
209261000865	L-aspartate oxidase; Provisional; Region: PRK06175
209261000866	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
209261000867	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
209261000868	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
209261000869	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
209261000870	DNA binding residues [nucleotide binding]
209261000871	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
209261000872	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
209261000873	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
209261000874	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
209261000875	anti-sigma E factor; Provisional; Region: rseB; PRK09455
209261000876	SoxR reducing system protein RseC; Provisional; Region: PRK10862
209261000877	GTP-binding protein LepA; Provisional; Region: PRK05433
209261000878	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
209261000879	G1 box; other site
209261000880	putative GEF interaction site [polypeptide binding]; other site
209261000881	GTP/Mg2+ binding site [chemical binding]; other site
209261000882	Switch I region; other site
209261000883	G2 box; other site
209261000884	G3 box; other site
209261000885	Switch II region; other site
209261000886	G4 box; other site
209261000887	G5 box; other site
209261000888	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
209261000889	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
209261000890	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
209261000891	signal peptidase I; Provisional; Region: PRK10861
209261000892	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
209261000893	Catalytic site [active]
209261000894	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
209261000895	ribonuclease III; Reviewed; Region: rnc; PRK00102
209261000896	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
209261000897	dimerization interface [polypeptide binding]; other site
209261000898	active site
209261000899	metal binding site [ion binding]; metal-binding site
209261000900	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
209261000901	dsRNA binding site [nucleotide binding]; other site
209261000902	GTPase Era; Reviewed; Region: era; PRK00089
209261000903	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
209261000904	G1 box; other site
209261000905	GTP/Mg2+ binding site [chemical binding]; other site
209261000906	Switch I region; other site
209261000907	G2 box; other site
209261000908	Switch II region; other site
209261000909	G3 box; other site
209261000910	G4 box; other site
209261000911	G5 box; other site
209261000912	KH domain; Region: KH_2; pfam07650
209261000913	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
209261000914	Recombination protein O N terminal; Region: RecO_N; pfam11967
209261000915	Recombination protein O C terminal; Region: RecO_C; pfam02565
209261000916	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
209261000917	active site
209261000918	hydrophilic channel; other site
209261000919	dimerization interface [polypeptide binding]; other site
209261000920	catalytic residues [active]
209261000921	active site lid [active]
209261000922	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
209261000923	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
209261000924	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261000925	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261000926	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
209261000927	dimerization interface [polypeptide binding]; other site
209261000928	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
209261000929	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261000930	putative substrate translocation pore; other site
209261000931	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
209261000932	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
209261000933	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
209261000934	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
209261000935	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
209261000936	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
209261000937	putative active site [active]
209261000938	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
209261000939	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
209261000940	putative active site [active]
209261000941	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
209261000942	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
209261000943	active site turn [active]
209261000944	phosphorylation site [posttranslational modification]
209261000945	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
209261000946	hypothetical protein; Provisional; Region: PRK11590
209261000947	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
209261000948	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
209261000949	nucleoside/Zn binding site; other site
209261000950	dimer interface [polypeptide binding]; other site
209261000951	catalytic motif [active]
209261000952	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
209261000953	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261000954	substrate binding pocket [chemical binding]; other site
209261000955	membrane-bound complex binding site; other site
209261000956	hinge residues; other site
209261000957	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
209261000958	N-acetyl-D-glucosamine binding site [chemical binding]; other site
209261000959	catalytic residue [active]
209261000960	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
209261000961	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
209261000962	dimerization interface [polypeptide binding]; other site
209261000963	ATP binding site [chemical binding]; other site
209261000964	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
209261000965	dimerization interface [polypeptide binding]; other site
209261000966	ATP binding site [chemical binding]; other site
209261000967	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
209261000968	putative active site [active]
209261000969	catalytic triad [active]
209261000970	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
209261000971	HAMP domain; Region: HAMP; pfam00672
209261000972	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261000973	dimer interface [polypeptide binding]; other site
209261000974	phosphorylation site [posttranslational modification]
209261000975	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261000976	ATP binding site [chemical binding]; other site
209261000977	Mg2+ binding site [ion binding]; other site
209261000978	G-X-G motif; other site
209261000979	hypothetical protein; Provisional; Region: PRK10722
209261000980	response regulator GlrR; Provisional; Region: PRK15115
209261000981	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261000982	active site
209261000983	phosphorylation site [posttranslational modification]
209261000984	intermolecular recognition site; other site
209261000985	dimerization interface [polypeptide binding]; other site
209261000986	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261000987	Walker A motif; other site
209261000988	ATP binding site [chemical binding]; other site
209261000989	Walker B motif; other site
209261000990	arginine finger; other site
209261000991	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
209261000992	Nitrogen regulatory protein P-II; Region: P-II; smart00938
209261000993	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
209261000994	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261000995	putative substrate translocation pore; other site
209261000996	POT family; Region: PTR2; pfam00854
209261000997	lysine decarboxylase CadA; Provisional; Region: PRK15400
209261000998	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
209261000999	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
209261001000	homodimer interface [polypeptide binding]; other site
209261001001	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261001002	catalytic residue [active]
209261001003	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
209261001004	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
209261001005	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
209261001006	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261001007	DNA binding site [nucleotide binding]
209261001008	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
209261001009	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
209261001010	heme-binding site [chemical binding]; other site
209261001011	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
209261001012	FAD binding pocket [chemical binding]; other site
209261001013	FAD binding motif [chemical binding]; other site
209261001014	phosphate binding motif [ion binding]; other site
209261001015	beta-alpha-beta structure motif; other site
209261001016	NAD binding pocket [chemical binding]; other site
209261001017	Heme binding  pocket [chemical binding]; other site
209261001018	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
209261001019	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
209261001020	dimer interface [polypeptide binding]; other site
209261001021	active site
209261001022	glycine-pyridoxal phosphate binding site [chemical binding]; other site
209261001023	folate binding site [chemical binding]; other site
209261001024	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
209261001025	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261001026	putative substrate translocation pore; other site
209261001027	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
209261001028	PRD domain; Region: PRD; pfam00874
209261001029	PRD domain; Region: PRD; pfam00874
209261001030	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
209261001031	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
209261001032	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
209261001033	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
209261001034	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
209261001035	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
209261001036	FAD binding pocket [chemical binding]; other site
209261001037	FAD binding motif [chemical binding]; other site
209261001038	phosphate binding motif [ion binding]; other site
209261001039	beta-alpha-beta structure motif; other site
209261001040	NAD binding pocket [chemical binding]; other site
209261001041	Iron coordination center [ion binding]; other site
209261001042	sulfite reductase, subunit A; Region: sulfite_red_A; TIGR02910
209261001043	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
209261001044	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
209261001045	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
209261001046	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
209261001047	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
209261001048	active site
209261001049	dimerization interface [polypeptide binding]; other site
209261001050	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
209261001051	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
209261001052	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
209261001053	Rrf2 family protein; Region: rrf2_super; TIGR00738
209261001054	cysteine desulfurase; Provisional; Region: PRK14012
209261001055	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
209261001056	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
209261001057	catalytic residue [active]
209261001058	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
209261001059	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
209261001060	trimerization site [polypeptide binding]; other site
209261001061	active site
209261001062	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
209261001063	co-chaperone HscB; Provisional; Region: hscB; PRK05014
209261001064	DnaJ domain; Region: DnaJ; pfam00226
209261001065	HSP70 interaction site [polypeptide binding]; other site
209261001066	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
209261001067	chaperone protein HscA; Provisional; Region: hscA; PRK05183
209261001068	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
209261001069	nucleotide binding site [chemical binding]; other site
209261001070	putative NEF/HSP70 interaction site [polypeptide binding]; other site
209261001071	SBD interface [polypeptide binding]; other site
209261001072	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
209261001073	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
209261001074	catalytic loop [active]
209261001075	iron binding site [ion binding]; other site
209261001076	hypothetical protein; Provisional; Region: PRK10721
209261001077	aminopeptidase B; Provisional; Region: PRK05015
209261001078	Peptidase; Region: DUF3663; pfam12404
209261001079	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
209261001080	interface (dimer of trimers) [polypeptide binding]; other site
209261001081	Substrate-binding/catalytic site; other site
209261001082	Zn-binding sites [ion binding]; other site
209261001083	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
209261001084	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
209261001085	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
209261001086	active site residue [active]
209261001087	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
209261001088	active site residue [active]
209261001089	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
209261001090	MG2 domain; Region: A2M_N; pfam01835
209261001091	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
209261001092	surface patch; other site
209261001093	thioester region; other site
209261001094	specificity defining residues; other site
209261001095	penicillin-binding protein 1C; Provisional; Region: PRK11240
209261001096	Transglycosylase; Region: Transgly; pfam00912
209261001097	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
209261001098	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
209261001099	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
209261001100	4Fe-4S binding domain; Region: Fer4; pfam00037
209261001101	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
209261001102	4Fe-4S binding domain; Region: Fer4; pfam00037
209261001103	hydrogenase 4 subunit H; Validated; Region: PRK08222
209261001104	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
209261001105	active site
209261001106	multimer interface [polypeptide binding]; other site
209261001107	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
209261001108	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261001109	FeS/SAM binding site; other site
209261001110	cytoskeletal protein RodZ; Provisional; Region: PRK10856
209261001111	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261001112	non-specific DNA binding site [nucleotide binding]; other site
209261001113	salt bridge; other site
209261001114	sequence-specific DNA binding site [nucleotide binding]; other site
209261001115	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
209261001116	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
209261001117	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
209261001118	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
209261001119	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
209261001120	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
209261001121	dimer interface [polypeptide binding]; other site
209261001122	motif 1; other site
209261001123	active site
209261001124	motif 2; other site
209261001125	motif 3; other site
209261001126	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
209261001127	anticodon binding site; other site
209261001128	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
209261001129	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
209261001130	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
209261001131	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
209261001132	Trp docking motif [polypeptide binding]; other site
209261001133	GTP-binding protein Der; Reviewed; Region: PRK00093
209261001134	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
209261001135	G1 box; other site
209261001136	GTP/Mg2+ binding site [chemical binding]; other site
209261001137	Switch I region; other site
209261001138	G2 box; other site
209261001139	Switch II region; other site
209261001140	G3 box; other site
209261001141	G4 box; other site
209261001142	G5 box; other site
209261001143	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
209261001144	G1 box; other site
209261001145	GTP/Mg2+ binding site [chemical binding]; other site
209261001146	Switch I region; other site
209261001147	G2 box; other site
209261001148	G3 box; other site
209261001149	Switch II region; other site
209261001150	G4 box; other site
209261001151	G5 box; other site
209261001152	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
209261001153	intimin-like protein SinH; Provisional; Region: PRK15318
209261001154	outer membrane protein RatA; Provisional; Region: PRK15315
209261001155	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
209261001156	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
209261001157	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
209261001158	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
209261001159	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
209261001160	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
209261001161	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
209261001162	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
209261001163	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
209261001164	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
209261001165	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
209261001166	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
209261001167	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
209261001168	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
209261001169	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
209261001170	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
209261001171	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
209261001172	generic binding surface II; other site
209261001173	generic binding surface I; other site
209261001174	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
209261001175	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
209261001176	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
209261001177	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
209261001178	active site
209261001179	GMP synthase; Reviewed; Region: guaA; PRK00074
209261001180	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
209261001181	AMP/PPi binding site [chemical binding]; other site
209261001182	candidate oxyanion hole; other site
209261001183	catalytic triad [active]
209261001184	potential glutamine specificity residues [chemical binding]; other site
209261001185	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
209261001186	ATP Binding subdomain [chemical binding]; other site
209261001187	Ligand Binding sites [chemical binding]; other site
209261001188	Dimerization subdomain; other site
209261001189	GIY-YIG domain of uncharacterized proteins from bacteria and their eukaryotic homologs; Region: GIY-YIG_COG3680; cd10440
209261001190	GIY-YIG motif/motif A; other site
209261001191	putative active site [active]
209261001192	putative metal binding site [ion binding]; other site
209261001193	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
209261001194	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
209261001195	MASE1; Region: MASE1; pfam05231
209261001196	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
209261001197	diguanylate cyclase; Region: GGDEF; smart00267
209261001198	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261001199	exopolyphosphatase; Provisional; Region: PRK10854
209261001200	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
209261001201	nucleotide binding site [chemical binding]; other site
209261001202	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
209261001203	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
209261001204	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
209261001205	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
209261001206	putative active site [active]
209261001207	catalytic site [active]
209261001208	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
209261001209	domain interface [polypeptide binding]; other site
209261001210	active site
209261001211	catalytic site [active]
209261001212	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
209261001213	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
209261001214	active site
209261001215	substrate binding site [chemical binding]; other site
209261001216	cosubstrate binding site; other site
209261001217	catalytic site [active]
209261001218	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
209261001219	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
209261001220	dimerization interface [polypeptide binding]; other site
209261001221	putative ATP binding site [chemical binding]; other site
209261001222	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
209261001223	active site
209261001224	uracil transporter; Provisional; Region: PRK10720
209261001225	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
209261001226	DNA replication initiation factor; Provisional; Region: PRK08084
209261001227	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
209261001228	ArsC family; Region: ArsC; pfam03960
209261001229	catalytic residues [active]
209261001230	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
209261001231	Peptidase family M48; Region: Peptidase_M48; cl12018
209261001232	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
209261001233	Domain of unknown function DUF20; Region: UPF0118; pfam01594
209261001234	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
209261001235	fructuronate transporter; Provisional; Region: PRK10034; cl15264
209261001236	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
209261001237	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
209261001238	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
209261001239	catalytic triad [active]
209261001240	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
209261001241	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
209261001242	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
209261001243	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
209261001244	dihydrodipicolinate synthase; Region: dapA; TIGR00674
209261001245	dimer interface [polypeptide binding]; other site
209261001246	active site
209261001247	catalytic residue [active]
209261001248	lipoprotein; Provisional; Region: PRK11679
209261001249	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
209261001250	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
209261001251	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
209261001252	ATP binding site [chemical binding]; other site
209261001253	active site
209261001254	substrate binding site [chemical binding]; other site
209261001255	Predicted metalloprotease [General function prediction only]; Region: COG2321
209261001256	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
209261001257	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
209261001258	Helicase; Region: Helicase_RecD; pfam05127
209261001259	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261001260	Coenzyme A binding pocket [chemical binding]; other site
209261001261	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
209261001262	hypothetical protein; Provisional; Region: PRK13664
209261001263	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
209261001264	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
209261001265	metal binding site [ion binding]; metal-binding site
209261001266	dimer interface [polypeptide binding]; other site
209261001267	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
209261001268	ArsC family; Region: ArsC; pfam03960
209261001269	putative catalytic residues [active]
209261001270	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
209261001271	Protein export membrane protein; Region: SecD_SecF; cl14618
209261001272	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
209261001273	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
209261001274	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261001275	dimerization interface [polypeptide binding]; other site
209261001276	Histidine kinase; Region: HisKA_3; pfam07730
209261001277	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261001278	ATP binding site [chemical binding]; other site
209261001279	Mg2+ binding site [ion binding]; other site
209261001280	G-X-G motif; other site
209261001281	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
209261001282	4Fe-4S binding domain; Region: Fer4; pfam00037
209261001283	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
209261001284	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261001285	putative periplasmic esterase; Provisional; Region: PRK03642
209261001286	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
209261001287	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
209261001288	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
209261001289	dimer interface [polypeptide binding]; other site
209261001290	ADP-ribose binding site [chemical binding]; other site
209261001291	active site
209261001292	nudix motif; other site
209261001293	metal binding site [ion binding]; metal-binding site
209261001294	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
209261001295	transketolase; Reviewed; Region: PRK12753
209261001296	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
209261001297	TPP-binding site [chemical binding]; other site
209261001298	dimer interface [polypeptide binding]; other site
209261001299	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
209261001300	PYR/PP interface [polypeptide binding]; other site
209261001301	dimer interface [polypeptide binding]; other site
209261001302	TPP binding site [chemical binding]; other site
209261001303	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
209261001304	transaldolase-like protein; Provisional; Region: PTZ00411
209261001305	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
209261001306	active site
209261001307	dimer interface [polypeptide binding]; other site
209261001308	catalytic residue [active]
209261001309	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
209261001310	Malic enzyme, N-terminal domain; Region: malic; pfam00390
209261001311	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
209261001312	putative NAD(P) binding site [chemical binding]; other site
209261001313	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
209261001314	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261001315	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
209261001316	putative hexamer interface [polypeptide binding]; other site
209261001317	putative hexagonal pore; other site
209261001318	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
209261001319	G1 box; other site
209261001320	GTP/Mg2+ binding site [chemical binding]; other site
209261001321	G2 box; other site
209261001322	Switch I region; other site
209261001323	G3 box; other site
209261001324	Switch II region; other site
209261001325	G4 box; other site
209261001326	G5 box; other site
209261001327	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
209261001328	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
209261001329	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
209261001330	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
209261001331	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
209261001332	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
209261001333	Hexamer interface [polypeptide binding]; other site
209261001334	Putative hexagonal pore residue; other site
209261001335	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
209261001336	Hexamer/Pentamer interface [polypeptide binding]; other site
209261001337	central pore; other site
209261001338	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
209261001339	putative catalytic cysteine [active]
209261001340	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
209261001341	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
209261001342	nucleotide binding site [chemical binding]; other site
209261001343	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
209261001344	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
209261001345	active site
209261001346	metal binding site [ion binding]; metal-binding site
209261001347	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
209261001348	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
209261001349	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
209261001350	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
209261001351	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
209261001352	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
209261001353	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
209261001354	putative hexamer interface [polypeptide binding]; other site
209261001355	putative hexagonal pore; other site
209261001356	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
209261001357	putative hexamer interface [polypeptide binding]; other site
209261001358	putative hexagonal pore; other site
209261001359	carboxysome structural protein EutK; Provisional; Region: PRK15466
209261001360	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
209261001361	Hexamer interface [polypeptide binding]; other site
209261001362	Hexagonal pore residue; other site
209261001363	transcriptional regulator EutR; Provisional; Region: PRK10130
209261001364	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261001365	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261001366	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
209261001367	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
209261001368	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
209261001369	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
209261001370	active site
209261001371	metal binding site [ion binding]; metal-binding site
209261001372	putative acetyltransferase; Provisional; Region: PRK03624
209261001373	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261001374	Coenzyme A binding pocket [chemical binding]; other site
209261001375	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
209261001376	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
209261001377	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
209261001378	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
209261001379	short chain dehydrogenase; Provisional; Region: PRK08226
209261001380	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
209261001381	NAD binding site [chemical binding]; other site
209261001382	homotetramer interface [polypeptide binding]; other site
209261001383	homodimer interface [polypeptide binding]; other site
209261001384	active site
209261001385	thiosulfate transporter subunit; Provisional; Region: PRK10852
209261001386	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
209261001387	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
209261001388	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261001389	dimer interface [polypeptide binding]; other site
209261001390	conserved gate region; other site
209261001391	putative PBP binding loops; other site
209261001392	ABC-ATPase subunit interface; other site
209261001393	sulfate transport protein; Provisional; Region: cysT; CHL00187
209261001394	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261001395	dimer interface [polypeptide binding]; other site
209261001396	conserved gate region; other site
209261001397	putative PBP binding loops; other site
209261001398	ABC-ATPase subunit interface; other site
209261001399	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
209261001400	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
209261001401	Walker A/P-loop; other site
209261001402	ATP binding site [chemical binding]; other site
209261001403	Q-loop/lid; other site
209261001404	ABC transporter signature motif; other site
209261001405	Walker B; other site
209261001406	D-loop; other site
209261001407	H-loop/switch region; other site
209261001408	TOBE-like domain; Region: TOBE_3; pfam12857
209261001409	cysteine synthase B; Region: cysM; TIGR01138
209261001410	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
209261001411	dimer interface [polypeptide binding]; other site
209261001412	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261001413	catalytic residue [active]
209261001414	hypothetical protein; Provisional; Region: PRK10318
209261001415	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
209261001416	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
209261001417	catalytic triad [active]
209261001418	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
209261001419	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261001420	DNA-binding site [nucleotide binding]; DNA binding site
209261001421	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261001422	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261001423	homodimer interface [polypeptide binding]; other site
209261001424	catalytic residue [active]
209261001425	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
209261001426	dimer interface [polypeptide binding]; other site
209261001427	pyridoxamine kinase; Validated; Region: PRK05756
209261001428	pyridoxal binding site [chemical binding]; other site
209261001429	ATP binding site [chemical binding]; other site
209261001430	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
209261001431	HPr interaction site; other site
209261001432	glycerol kinase (GK) interaction site [polypeptide binding]; other site
209261001433	active site
209261001434	phosphorylation site [posttranslational modification]
209261001435	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
209261001436	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
209261001437	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
209261001438	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
209261001439	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
209261001440	dimerization domain swap beta strand [polypeptide binding]; other site
209261001441	regulatory protein interface [polypeptide binding]; other site
209261001442	active site
209261001443	regulatory phosphorylation site [posttranslational modification]; other site
209261001444	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
209261001445	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
209261001446	dimer interface [polypeptide binding]; other site
209261001447	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261001448	catalytic residue [active]
209261001449	putative sulfate transport protein CysZ; Validated; Region: PRK04949
209261001450	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
209261001451	cell division protein ZipA; Provisional; Region: PRK03427
209261001452	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
209261001453	FtsZ protein binding site [polypeptide binding]; other site
209261001454	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
209261001455	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
209261001456	nucleotide binding pocket [chemical binding]; other site
209261001457	K-X-D-G motif; other site
209261001458	catalytic site [active]
209261001459	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
209261001460	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
209261001461	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
209261001462	Dimer interface [polypeptide binding]; other site
209261001463	BRCT sequence motif; other site
209261001464	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
209261001465	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
209261001466	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
209261001467	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261001468	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261001469	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
209261001470	putative dimerization interface [polypeptide binding]; other site
209261001471	hypothetical protein; Provisional; Region: PRK11528
209261001472	purine nucleoside phosphorylase; Provisional; Region: PRK08202
209261001473	nucleoside transporter; Region: 2A0110; TIGR00889
209261001474	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261001475	putative substrate translocation pore; other site
209261001476	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
209261001477	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261001478	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
209261001479	putative dimerization interface [polypeptide binding]; other site
209261001480	putative substrate binding pocket [chemical binding]; other site
209261001481	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
209261001482	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
209261001483	active site
209261001484	HIGH motif; other site
209261001485	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
209261001486	active site
209261001487	KMSKS motif; other site
209261001488	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
209261001489	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
209261001490	MASE1; Region: MASE1; pfam05231
209261001491	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
209261001492	diguanylate cyclase; Region: GGDEF; smart00267
209261001493	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261001494	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
209261001495	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
209261001496	Nucleoside recognition; Region: Gate; pfam07670
209261001497	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
209261001498	manganese transport protein MntH; Reviewed; Region: PRK00701
209261001499	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
209261001500	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
209261001501	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
209261001502	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
209261001503	active site
209261001504	catalytic tetrad [active]
209261001505	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
209261001506	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
209261001507	dimer interface [polypeptide binding]; other site
209261001508	PYR/PP interface [polypeptide binding]; other site
209261001509	TPP binding site [chemical binding]; other site
209261001510	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
209261001511	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
209261001512	TPP-binding site [chemical binding]; other site
209261001513	dimer interface [polypeptide binding]; other site
209261001514	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
209261001515	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
209261001516	Cl- selectivity filter; other site
209261001517	Cl- binding residues [ion binding]; other site
209261001518	pore gating glutamate residue; other site
209261001519	dimer interface [polypeptide binding]; other site
209261001520	glucokinase; Provisional; Region: glk; PRK00292
209261001521	glucokinase, proteobacterial type; Region: glk; TIGR00749
209261001522	aminotransferase; Validated; Region: PRK08175
209261001523	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261001524	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261001525	homodimer interface [polypeptide binding]; other site
209261001526	catalytic residue [active]
209261001527	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261001528	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
209261001529	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
209261001530	putative acyl-acceptor binding pocket; other site
209261001531	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
209261001532	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
209261001533	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261001534	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261001535	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
209261001536	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
209261001537	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
209261001538	HAMP domain; Region: HAMP; pfam00672
209261001539	dimerization interface [polypeptide binding]; other site
209261001540	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261001541	dimer interface [polypeptide binding]; other site
209261001542	phosphorylation site [posttranslational modification]
209261001543	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261001544	ATP binding site [chemical binding]; other site
209261001545	Mg2+ binding site [ion binding]; other site
209261001546	G-X-G motif; other site
209261001547	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
209261001548	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261001549	active site
209261001550	phosphorylation site [posttranslational modification]
209261001551	intermolecular recognition site; other site
209261001552	dimerization interface [polypeptide binding]; other site
209261001553	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
209261001554	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
209261001555	outer membrane protease; Reviewed; Region: PRK10993
209261001556	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
209261001557	Predicted membrane protein [Function unknown]; Region: COG2246
209261001558	GtrA-like protein; Region: GtrA; pfam04138
209261001559	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
209261001560	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
209261001561	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
209261001562	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
209261001563	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
209261001564	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
209261001565	dimer interface [polypeptide binding]; other site
209261001566	active site
209261001567	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
209261001568	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
209261001569	substrate binding site [chemical binding]; other site
209261001570	oxyanion hole (OAH) forming residues; other site
209261001571	trimer interface [polypeptide binding]; other site
209261001572	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
209261001573	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
209261001574	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
209261001575	catalytic core [active]
209261001576	hypothetical protein; Provisional; Region: PRK04946
209261001577	Smr domain; Region: Smr; pfam01713
209261001578	HemK family putative methylases; Region: hemK_fam; TIGR00536
209261001579	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261001580	S-adenosylmethionine binding site [chemical binding]; other site
209261001581	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
209261001582	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
209261001583	Tetramer interface [polypeptide binding]; other site
209261001584	active site
209261001585	FMN-binding site [chemical binding]; other site
209261001586	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
209261001587	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
209261001588	hypothetical protein; Provisional; Region: PRK10621
209261001589	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
209261001590	YfcL protein; Region: YfcL; pfam08891
209261001591	Uncharacterized conserved protein [Function unknown]; Region: COG4121
209261001592	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
209261001593	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
209261001594	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
209261001595	dimer interface [polypeptide binding]; other site
209261001596	active site
209261001597	CAAX protease self-immunity; Region: Abi; pfam02517
209261001598	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
209261001599	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261001600	non-specific DNA binding site [nucleotide binding]; other site
209261001601	salt bridge; other site
209261001602	sequence-specific DNA binding site [nucleotide binding]; other site
209261001603	putative transporter; Provisional; Region: PRK12382
209261001604	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261001605	putative substrate translocation pore; other site
209261001606	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
209261001607	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
209261001608	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
209261001609	ligand binding site [chemical binding]; other site
209261001610	NAD binding site [chemical binding]; other site
209261001611	catalytic site [active]
209261001612	homodimer interface [polypeptide binding]; other site
209261001613	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
209261001614	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
209261001615	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
209261001616	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
209261001617	dimerization interface 3.5A [polypeptide binding]; other site
209261001618	active site
209261001619	hypothetical protein; Provisional; Region: PRK10847
209261001620	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
209261001621	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
209261001622	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
209261001623	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
209261001624	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
209261001625	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
209261001626	cell division protein DedD; Provisional; Region: PRK11633
209261001627	Sporulation related domain; Region: SPOR; pfam05036
209261001628	colicin V production protein; Provisional; Region: PRK10845
209261001629	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
209261001630	amidophosphoribosyltransferase; Provisional; Region: PRK09246
209261001631	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
209261001632	active site
209261001633	tetramer interface [polypeptide binding]; other site
209261001634	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
209261001635	active site
209261001636	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
209261001637	PAS fold; Region: PAS_4; pfam08448
209261001638	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
209261001639	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261001640	Walker A motif; other site
209261001641	ATP binding site [chemical binding]; other site
209261001642	Walker B motif; other site
209261001643	arginine finger; other site
209261001644	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
209261001645	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
209261001646	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
209261001647	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
209261001648	catalytic residue [active]
209261001649	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
209261001650	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
209261001651	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
209261001652	dimer interface [polypeptide binding]; other site
209261001653	active site
209261001654	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
209261001655	substrate binding site [chemical binding]; other site
209261001656	catalytic residue [active]
209261001657	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
209261001658	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
209261001659	Flavoprotein; Region: Flavoprotein; pfam02441
209261001660	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
209261001661	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261001662	substrate binding pocket [chemical binding]; other site
209261001663	membrane-bound complex binding site; other site
209261001664	hinge residues; other site
209261001665	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
209261001666	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261001667	substrate binding pocket [chemical binding]; other site
209261001668	membrane-bound complex binding site; other site
209261001669	hinge residues; other site
209261001670	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
209261001671	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261001672	dimer interface [polypeptide binding]; other site
209261001673	conserved gate region; other site
209261001674	putative PBP binding loops; other site
209261001675	ABC-ATPase subunit interface; other site
209261001676	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
209261001677	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261001678	dimer interface [polypeptide binding]; other site
209261001679	conserved gate region; other site
209261001680	putative PBP binding loops; other site
209261001681	ABC-ATPase subunit interface; other site
209261001682	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
209261001683	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
209261001684	Walker A/P-loop; other site
209261001685	ATP binding site [chemical binding]; other site
209261001686	Q-loop/lid; other site
209261001687	ABC transporter signature motif; other site
209261001688	Walker B; other site
209261001689	D-loop; other site
209261001690	H-loop/switch region; other site
209261001691	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
209261001692	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
209261001693	putative NAD(P) binding site [chemical binding]; other site
209261001694	putative active site [active]
209261001695	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
209261001696	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
209261001697	C-terminal domain interface [polypeptide binding]; other site
209261001698	GSH binding site (G-site) [chemical binding]; other site
209261001699	dimer interface [polypeptide binding]; other site
209261001700	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
209261001701	N-terminal domain interface [polypeptide binding]; other site
209261001702	putative dimer interface [polypeptide binding]; other site
209261001703	active site
209261001704	glutathione S-transferase; Provisional; Region: PRK15113
209261001705	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
209261001706	C-terminal domain interface [polypeptide binding]; other site
209261001707	GSH binding site (G-site) [chemical binding]; other site
209261001708	dimer interface [polypeptide binding]; other site
209261001709	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
209261001710	N-terminal domain interface [polypeptide binding]; other site
209261001711	putative dimer interface [polypeptide binding]; other site
209261001712	putative substrate binding pocket (H-site) [chemical binding]; other site
209261001713	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
209261001714	active site
209261001715	metal binding site [ion binding]; metal-binding site
209261001716	homotetramer interface [polypeptide binding]; other site
209261001717	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
209261001718	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
209261001719	nudix motif; other site
209261001720	Transcriptional regulators [Transcription]; Region: PurR; COG1609
209261001721	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261001722	DNA binding site [nucleotide binding]
209261001723	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
209261001724	putative dimerization interface [polypeptide binding]; other site
209261001725	putative ligand binding site [chemical binding]; other site
209261001726	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
209261001727	active site
209261001728	phosphorylation site [posttranslational modification]
209261001729	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
209261001730	active site
209261001731	P-loop; other site
209261001732	phosphorylation site [posttranslational modification]
209261001733	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
209261001734	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
209261001735	TPP-binding site [chemical binding]; other site
209261001736	dimer interface [polypeptide binding]; other site
209261001737	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
209261001738	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
209261001739	PYR/PP interface [polypeptide binding]; other site
209261001740	dimer interface [polypeptide binding]; other site
209261001741	TPP binding site [chemical binding]; other site
209261001742	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
209261001743	hypothetical protein; Provisional; Region: PRK11588
209261001744	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
209261001745	phosphate acetyltransferase; Reviewed; Region: PRK05632
209261001746	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
209261001747	DRTGG domain; Region: DRTGG; pfam07085
209261001748	phosphate acetyltransferase; Region: pta; TIGR00651
209261001749	propionate/acetate kinase; Provisional; Region: PRK12379
209261001750	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
209261001751	hypothetical protein; Provisional; Region: PRK01816
209261001752	hypothetical protein; Validated; Region: PRK05445
209261001753	putative phosphatase; Provisional; Region: PRK11587
209261001754	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261001755	motif II; other site
209261001756	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
209261001757	transmembrane helices; other site
209261001758	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
209261001759	TrkA-C domain; Region: TrkA_C; pfam02080
209261001760	TrkA-C domain; Region: TrkA_C; pfam02080
209261001761	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
209261001762	5'-nucleotidase; Provisional; Region: PRK03826
209261001763	aminotransferase AlaT; Validated; Region: PRK09265
209261001764	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261001765	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261001766	homodimer interface [polypeptide binding]; other site
209261001767	catalytic residue [active]
209261001768	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
209261001769	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261001770	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
209261001771	putative dimerization interface [polypeptide binding]; other site
209261001772	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
209261001773	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
209261001774	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
209261001775	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
209261001776	NADH dehydrogenase subunit D; Validated; Region: PRK06075
209261001777	NADH dehydrogenase subunit E; Validated; Region: PRK07539
209261001778	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
209261001779	putative dimer interface [polypeptide binding]; other site
209261001780	[2Fe-2S] cluster binding site [ion binding]; other site
209261001781	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
209261001782	SLBB domain; Region: SLBB; pfam10531
209261001783	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
209261001784	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
209261001785	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
209261001786	catalytic loop [active]
209261001787	iron binding site [ion binding]; other site
209261001788	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
209261001789	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
209261001790	[4Fe-4S] binding site [ion binding]; other site
209261001791	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
209261001792	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
209261001793	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
209261001794	4Fe-4S binding domain; Region: Fer4; pfam00037
209261001795	4Fe-4S binding domain; Region: Fer4; pfam00037
209261001796	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
209261001797	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
209261001798	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
209261001799	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
209261001800	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
209261001801	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
209261001802	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
209261001803	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
209261001804	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
209261001805	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
209261001806	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
209261001807	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
209261001808	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261001809	active site
209261001810	phosphorylation site [posttranslational modification]
209261001811	intermolecular recognition site; other site
209261001812	dimerization interface [polypeptide binding]; other site
209261001813	ribonuclease BN; Region: true_RNase_BN; TIGR02649
209261001814	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261001815	Coenzyme A binding pocket [chemical binding]; other site
209261001816	hypothetical protein; Provisional; Region: PRK10404
209261001817	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
209261001818	isochorismate synthases; Region: isochor_syn; TIGR00543
209261001819	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
209261001820	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
209261001821	dimer interface [polypeptide binding]; other site
209261001822	tetramer interface [polypeptide binding]; other site
209261001823	PYR/PP interface [polypeptide binding]; other site
209261001824	TPP binding site [chemical binding]; other site
209261001825	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
209261001826	TPP-binding site; other site
209261001827	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
209261001828	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
209261001829	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
209261001830	substrate binding site [chemical binding]; other site
209261001831	oxyanion hole (OAH) forming residues; other site
209261001832	trimer interface [polypeptide binding]; other site
209261001833	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
209261001834	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
209261001835	active site
209261001836	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
209261001837	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
209261001838	acyl-activating enzyme (AAE) consensus motif; other site
209261001839	putative AMP binding site [chemical binding]; other site
209261001840	putative active site [active]
209261001841	putative CoA binding site [chemical binding]; other site
209261001842	signal transduction protein PmrD; Provisional; Region: PRK15450
209261001843	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
209261001844	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
209261001845	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
209261001846	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
209261001847	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
209261001848	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
209261001849	putative active site [active]
209261001850	putative catalytic site [active]
209261001851	putative Zn binding site [ion binding]; other site
209261001852	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
209261001853	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
209261001854	active site
209261001855	substrate binding site [chemical binding]; other site
209261001856	cosubstrate binding site; other site
209261001857	catalytic site [active]
209261001858	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
209261001859	active site
209261001860	hexamer interface [polypeptide binding]; other site
209261001861	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
209261001862	NAD binding site [chemical binding]; other site
209261001863	substrate binding site [chemical binding]; other site
209261001864	active site
209261001865	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
209261001866	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
209261001867	Ligand binding site; other site
209261001868	Putative Catalytic site; other site
209261001869	DXD motif; other site
209261001870	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
209261001871	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
209261001872	inhibitor-cofactor binding pocket; inhibition site
209261001873	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261001874	catalytic residue [active]
209261001875	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
209261001876	catalytic core [active]
209261001877	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
209261001878	YfaZ precursor; Region: YfaZ; pfam07437
209261001879	hypothetical protein; Provisional; Region: PRK03673
209261001880	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
209261001881	putative MPT binding site; other site
209261001882	Competence-damaged protein; Region: CinA; cl00666
209261001883	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
209261001884	Transcriptional regulator [Transcription]; Region: IclR; COG1414
209261001885	Bacterial transcriptional regulator; Region: IclR; pfam01614
209261001886	L-rhamnonate dehydratase; Provisional; Region: PRK15440
209261001887	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
209261001888	putative active site pocket [active]
209261001889	putative metal binding site [ion binding]; other site
209261001890	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261001891	D-galactonate transporter; Region: 2A0114; TIGR00893
209261001892	putative substrate translocation pore; other site
209261001893	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
209261001894	Competence-damaged protein; Region: CinA; cl00666
209261001895	deubiquitinase SseL; Provisional; Region: PRK14848
209261001896	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
209261001897	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
209261001898	Cysteine-rich domain; Region: CCG; pfam02754
209261001899	Cysteine-rich domain; Region: CCG; pfam02754
209261001900	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
209261001901	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
209261001902	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
209261001903	hydroxyglutarate oxidase; Provisional; Region: PRK11728
209261001904	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
209261001905	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
209261001906	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261001907	putative substrate translocation pore; other site
209261001908	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
209261001909	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
209261001910	active site
209261001911	catalytic site [active]
209261001912	metal binding site [ion binding]; metal-binding site
209261001913	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
209261001914	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261001915	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
209261001916	dimerization interface [polypeptide binding]; other site
209261001917	Major Facilitator Superfamily; Region: MFS_1; pfam07690
209261001918	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261001919	putative substrate translocation pore; other site
209261001920	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
209261001921	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
209261001922	catalytic loop [active]
209261001923	iron binding site [ion binding]; other site
209261001924	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
209261001925	dimer interface [polypeptide binding]; other site
209261001926	putative radical transfer pathway; other site
209261001927	diiron center [ion binding]; other site
209261001928	tyrosyl radical; other site
209261001929	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
209261001930	ATP cone domain; Region: ATP-cone; pfam03477
209261001931	Class I ribonucleotide reductase; Region: RNR_I; cd01679
209261001932	active site
209261001933	dimer interface [polypeptide binding]; other site
209261001934	catalytic residues [active]
209261001935	effector binding site; other site
209261001936	R2 peptide binding site; other site
209261001937	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
209261001938	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261001939	S-adenosylmethionine binding site [chemical binding]; other site
209261001940	Transcriptional regulators [Transcription]; Region: GntR; COG1802
209261001941	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261001942	DNA-binding site [nucleotide binding]; DNA binding site
209261001943	FCD domain; Region: FCD; pfam07729
209261001944	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
209261001945	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
209261001946	active site pocket [active]
209261001947	DNA gyrase subunit A; Validated; Region: PRK05560
209261001948	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
209261001949	CAP-like domain; other site
209261001950	active site
209261001951	primary dimer interface [polypeptide binding]; other site
209261001952	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
209261001953	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
209261001954	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
209261001955	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
209261001956	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
209261001957	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
209261001958	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261001959	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
209261001960	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261001961	dimer interface [polypeptide binding]; other site
209261001962	phosphorylation site [posttranslational modification]
209261001963	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261001964	ATP binding site [chemical binding]; other site
209261001965	Mg2+ binding site [ion binding]; other site
209261001966	G-X-G motif; other site
209261001967	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
209261001968	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261001969	active site
209261001970	phosphorylation site [posttranslational modification]
209261001971	intermolecular recognition site; other site
209261001972	dimerization interface [polypeptide binding]; other site
209261001973	transcriptional regulator RcsB; Provisional; Region: PRK10840
209261001974	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261001975	active site
209261001976	phosphorylation site [posttranslational modification]
209261001977	intermolecular recognition site; other site
209261001978	dimerization interface [polypeptide binding]; other site
209261001979	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261001980	DNA binding residues [nucleotide binding]
209261001981	dimerization interface [polypeptide binding]; other site
209261001982	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
209261001983	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261001984	ATP binding site [chemical binding]; other site
209261001985	G-X-G motif; other site
209261001986	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
209261001987	putative binding surface; other site
209261001988	active site
209261001989	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
209261001990	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
209261001991	trimer interface [polypeptide binding]; other site
209261001992	eyelet of channel; other site
209261001993	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
209261001994	ApbE family; Region: ApbE; pfam02424
209261001995	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
209261001996	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
209261001997	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261001998	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
209261001999	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
209261002000	DNA binding site [nucleotide binding]
209261002001	active site
209261002002	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
209261002003	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
209261002004	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
209261002005	Walker A/P-loop; other site
209261002006	ATP binding site [chemical binding]; other site
209261002007	Q-loop/lid; other site
209261002008	ABC transporter signature motif; other site
209261002009	Walker B; other site
209261002010	D-loop; other site
209261002011	H-loop/switch region; other site
209261002012	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
209261002013	secondary substrate binding site; other site
209261002014	primary substrate binding site; other site
209261002015	inhibition loop; other site
209261002016	dimerization interface [polypeptide binding]; other site
209261002017	ferredoxin-type protein; Provisional; Region: PRK10194
209261002018	4Fe-4S binding domain; Region: Fer4; cl02805
209261002019	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
209261002020	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
209261002021	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
209261002022	[4Fe-4S] binding site [ion binding]; other site
209261002023	molybdopterin cofactor binding site; other site
209261002024	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
209261002025	molybdopterin cofactor binding site; other site
209261002026	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
209261002027	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
209261002028	4Fe-4S binding domain; Region: Fer4_5; pfam12801
209261002029	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
209261002030	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
209261002031	cytochrome c-type protein NapC; Provisional; Region: PRK10617
209261002032	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
209261002033	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
209261002034	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261002035	Walker A/P-loop; other site
209261002036	ATP binding site [chemical binding]; other site
209261002037	Q-loop/lid; other site
209261002038	ABC transporter signature motif; other site
209261002039	Walker B; other site
209261002040	D-loop; other site
209261002041	H-loop/switch region; other site
209261002042	ABC-type transport system involved in cytochrome c biogenesis, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CcmB; COG2386
209261002043	heme exporter protein CcmC; Region: ccmC; TIGR01191
209261002044	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
209261002045	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
209261002046	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
209261002047	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
209261002048	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
209261002049	catalytic residues [active]
209261002050	central insert; other site
209261002051	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
209261002052	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
209261002053	transcriptional regulator NarP; Provisional; Region: PRK10403
209261002054	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261002055	active site
209261002056	phosphorylation site [posttranslational modification]
209261002057	intermolecular recognition site; other site
209261002058	dimerization interface [polypeptide binding]; other site
209261002059	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261002060	DNA binding residues [nucleotide binding]
209261002061	dimerization interface [polypeptide binding]; other site
209261002062	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
209261002063	DinI-like family; Region: DinI; cl11630
209261002064	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
209261002065	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
209261002066	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
209261002067	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
209261002068	Leucine-rich repeats; other site
209261002069	Substrate binding site [chemical binding]; other site
209261002070	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
209261002071	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
209261002072	Sulfatase; Region: Sulfatase; cl17466
209261002073	hypothetical protein; Provisional; Region: PRK13689
209261002074	Nucleoid-associated protein [General function prediction only]; Region: COG3081
209261002075	nucleoid-associated protein NdpA; Validated; Region: PRK00378
209261002076	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
209261002077	5S rRNA interface [nucleotide binding]; other site
209261002078	CTC domain interface [polypeptide binding]; other site
209261002079	L16 interface [polypeptide binding]; other site
209261002080	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
209261002081	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261002082	ATP binding site [chemical binding]; other site
209261002083	putative Mg++ binding site [ion binding]; other site
209261002084	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261002085	nucleotide binding region [chemical binding]; other site
209261002086	ATP-binding site [chemical binding]; other site
209261002087	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
209261002088	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
209261002089	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
209261002090	RNA binding surface [nucleotide binding]; other site
209261002091	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
209261002092	active site
209261002093	uracil binding [chemical binding]; other site
209261002094	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261002095	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
209261002096	putative substrate translocation pore; other site
209261002097	hypothetical protein; Provisional; Region: PRK11835
209261002098	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
209261002099	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261002100	Walker A/P-loop; other site
209261002101	ATP binding site [chemical binding]; other site
209261002102	Q-loop/lid; other site
209261002103	ABC transporter signature motif; other site
209261002104	Walker B; other site
209261002105	D-loop; other site
209261002106	H-loop/switch region; other site
209261002107	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
209261002108	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261002109	Walker A/P-loop; other site
209261002110	ATP binding site [chemical binding]; other site
209261002111	Q-loop/lid; other site
209261002112	ABC transporter signature motif; other site
209261002113	Walker B; other site
209261002114	D-loop; other site
209261002115	H-loop/switch region; other site
209261002116	microcin C ABC transporter permease; Provisional; Region: PRK15021
209261002117	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261002118	dimer interface [polypeptide binding]; other site
209261002119	conserved gate region; other site
209261002120	ABC-ATPase subunit interface; other site
209261002121	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
209261002122	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261002123	dimer interface [polypeptide binding]; other site
209261002124	conserved gate region; other site
209261002125	putative PBP binding loops; other site
209261002126	ABC-ATPase subunit interface; other site
209261002127	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
209261002128	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
209261002129	phage resistance protein; Provisional; Region: PRK10551
209261002130	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
209261002131	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261002132	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
209261002133	NlpC/P60 family; Region: NLPC_P60; pfam00877
209261002134	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
209261002135	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
209261002136	active site
209261002137	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
209261002138	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
209261002139	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
209261002140	elongation factor P; Provisional; Region: PRK04542
209261002141	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
209261002142	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
209261002143	RNA binding site [nucleotide binding]; other site
209261002144	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
209261002145	RNA binding site [nucleotide binding]; other site
209261002146	Flagellin N-methylase; Region: FliB; cl00497
209261002147	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
209261002148	sugar efflux transporter B; Provisional; Region: PRK15011
209261002149	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261002150	putative substrate translocation pore; other site
209261002151	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
209261002152	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
209261002153	active site
209261002154	phosphorylation site [posttranslational modification]
209261002155	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
209261002156	dimerization domain swap beta strand [polypeptide binding]; other site
209261002157	regulatory protein interface [polypeptide binding]; other site
209261002158	active site
209261002159	regulatory phosphorylation site [posttranslational modification]; other site
209261002160	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
209261002161	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
209261002162	putative substrate binding site [chemical binding]; other site
209261002163	putative ATP binding site [chemical binding]; other site
209261002164	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
209261002165	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
209261002166	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
209261002167	active site
209261002168	P-loop; other site
209261002169	phosphorylation site [posttranslational modification]
209261002170	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
209261002171	endonuclease IV; Provisional; Region: PRK01060
209261002172	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
209261002173	AP (apurinic/apyrimidinic) site pocket; other site
209261002174	DNA interaction; other site
209261002175	Metal-binding active site; metal-binding site
209261002176	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
209261002177	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
209261002178	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261002179	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
209261002180	putative dimerization interface [polypeptide binding]; other site
209261002181	lysine transporter; Provisional; Region: PRK10836
209261002182	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
209261002183	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
209261002184	N-terminal plug; other site
209261002185	ligand-binding site [chemical binding]; other site
209261002186	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
209261002187	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
209261002188	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261002189	motif II; other site
209261002190	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
209261002191	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
209261002192	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
209261002193	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261002194	non-specific DNA binding site [nucleotide binding]; other site
209261002195	salt bridge; other site
209261002196	sequence-specific DNA binding site [nucleotide binding]; other site
209261002197	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
209261002198	S-formylglutathione hydrolase; Region: PLN02442
209261002199	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
209261002200	GTP cyclohydrolase I; Provisional; Region: PLN03044
209261002201	active site
209261002202	Predicted membrane protein [Function unknown]; Region: COG2311
209261002203	hypothetical protein; Provisional; Region: PRK10835
209261002204	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
209261002205	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261002206	DNA binding site [nucleotide binding]
209261002207	domain linker motif; other site
209261002208	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
209261002209	dimerization interface (closed form) [polypeptide binding]; other site
209261002210	ligand binding site [chemical binding]; other site
209261002211	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
209261002212	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
209261002213	ligand binding site [chemical binding]; other site
209261002214	calcium binding site [ion binding]; other site
209261002215	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
209261002216	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
209261002217	TM-ABC transporter signature motif; other site
209261002218	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
209261002219	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
209261002220	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261002221	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
209261002222	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
209261002223	putative active site [active]
209261002224	cytidine deaminase; Provisional; Region: PRK09027
209261002225	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
209261002226	active site
209261002227	catalytic motif [active]
209261002228	Zn binding site [ion binding]; other site
209261002229	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
209261002230	active site
209261002231	catalytic motif [active]
209261002232	Zn binding site [ion binding]; other site
209261002233	hypothetical protein; Provisional; Region: PRK10711
209261002234	hypothetical protein; Provisional; Region: PRK01821
209261002235	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
209261002236	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261002237	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
209261002238	dimerization interface [polypeptide binding]; other site
209261002239	benzoate transport; Region: 2A0115; TIGR00895
209261002240	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261002241	putative substrate translocation pore; other site
209261002242	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
209261002243	Cupin domain; Region: Cupin_2; pfam07883
209261002244	Cupin domain; Region: Cupin_2; pfam07883
209261002245	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
209261002246	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
209261002247	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
209261002248	maleylacetoacetate isomerase; Region: maiA; TIGR01262
209261002249	C-terminal domain interface [polypeptide binding]; other site
209261002250	GSH binding site (G-site) [chemical binding]; other site
209261002251	putative dimer interface [polypeptide binding]; other site
209261002252	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
209261002253	dimer interface [polypeptide binding]; other site
209261002254	N-terminal domain interface [polypeptide binding]; other site
209261002255	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
209261002256	salicylate hydroxylase; Provisional; Region: PRK08163
209261002257	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
209261002258	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
209261002259	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
209261002260	FMN binding site [chemical binding]; other site
209261002261	active site
209261002262	catalytic residues [active]
209261002263	substrate binding site [chemical binding]; other site
209261002264	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
209261002265	oxidoreductase; Provisional; Region: PRK12743
209261002266	classical (c) SDRs; Region: SDR_c; cd05233
209261002267	NAD(P) binding site [chemical binding]; other site
209261002268	active site
209261002269	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
209261002270	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
209261002271	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
209261002272	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
209261002273	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
209261002274	D-lactate dehydrogenase; Provisional; Region: PRK11183
209261002275	FAD binding domain; Region: FAD_binding_4; pfam01565
209261002276	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
209261002277	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
209261002278	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
209261002279	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
209261002280	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
209261002281	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261002282	dimer interface [polypeptide binding]; other site
209261002283	conserved gate region; other site
209261002284	ABC-ATPase subunit interface; other site
209261002285	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
209261002286	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
209261002287	Walker A/P-loop; other site
209261002288	ATP binding site [chemical binding]; other site
209261002289	Q-loop/lid; other site
209261002290	ABC transporter signature motif; other site
209261002291	Walker B; other site
209261002292	D-loop; other site
209261002293	H-loop/switch region; other site
209261002294	CBS domain; Region: CBS; pfam00571
209261002295	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
209261002296	putative PBP binding loops; other site
209261002297	ABC-ATPase subunit interface; other site
209261002298	hypothetical protein; Provisional; Region: PRK13681
209261002299	transcriptional regulator MirA; Provisional; Region: PRK15043
209261002300	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
209261002301	DNA binding residues [nucleotide binding]
209261002302	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
209261002303	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
209261002304	GAF domain; Region: GAF; pfam01590
209261002305	Histidine kinase; Region: His_kinase; pfam06580
209261002306	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261002307	ATP binding site [chemical binding]; other site
209261002308	Mg2+ binding site [ion binding]; other site
209261002309	G-X-G motif; other site
209261002310	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
209261002311	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261002312	active site
209261002313	phosphorylation site [posttranslational modification]
209261002314	intermolecular recognition site; other site
209261002315	dimerization interface [polypeptide binding]; other site
209261002316	LytTr DNA-binding domain; Region: LytTR; pfam04397
209261002317	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
209261002318	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
209261002319	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
209261002320	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
209261002321	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
209261002322	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
209261002323	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
209261002324	active site
209261002325	HIGH motif; other site
209261002326	KMSKS motif; other site
209261002327	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
209261002328	tRNA binding surface [nucleotide binding]; other site
209261002329	anticodon binding site; other site
209261002330	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
209261002331	dimer interface [polypeptide binding]; other site
209261002332	putative tRNA-binding site [nucleotide binding]; other site
209261002333	antiporter inner membrane protein; Provisional; Region: PRK11670
209261002334	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
209261002335	Walker A motif; other site
209261002336	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
209261002337	fimbrial chaperone protein; Provisional; Region: PRK15220
209261002338	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
209261002339	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261002340	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261002341	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
209261002342	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
209261002343	Predicted integral membrane protein [Function unknown]; Region: COG5455
209261002344	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
209261002345	substrate binding site [chemical binding]; other site
209261002346	multimerization interface [polypeptide binding]; other site
209261002347	ATP binding site [chemical binding]; other site
209261002348	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
209261002349	dimer interface [polypeptide binding]; other site
209261002350	substrate binding site [chemical binding]; other site
209261002351	ATP binding site [chemical binding]; other site
209261002352	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
209261002353	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261002354	DNA-binding site [nucleotide binding]; DNA binding site
209261002355	UTRA domain; Region: UTRA; pfam07702
209261002356	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
209261002357	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
209261002358	substrate binding site [chemical binding]; other site
209261002359	ATP binding site [chemical binding]; other site
209261002360	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
209261002361	nucleoside transporter; Region: 2A0110; TIGR00889
209261002362	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261002363	putative substrate translocation pore; other site
209261002364	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
209261002365	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
209261002366	putative active site; other site
209261002367	catalytic residue [active]
209261002368	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
209261002369	putative protease; Provisional; Region: PRK15452
209261002370	Peptidase family U32; Region: Peptidase_U32; pfam01136
209261002371	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
209261002372	Tetratricopeptide repeat; Region: TPR_12; pfam13424
209261002373	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
209261002374	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
209261002375	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
209261002376	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261002377	active site
209261002378	phosphorylation site [posttranslational modification]
209261002379	intermolecular recognition site; other site
209261002380	dimerization interface [polypeptide binding]; other site
209261002381	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261002382	DNA binding site [nucleotide binding]
209261002383	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
209261002384	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261002385	dimerization interface [polypeptide binding]; other site
209261002386	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261002387	dimer interface [polypeptide binding]; other site
209261002388	phosphorylation site [posttranslational modification]
209261002389	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261002390	ATP binding site [chemical binding]; other site
209261002391	Mg2+ binding site [ion binding]; other site
209261002392	G-X-G motif; other site
209261002393	putative transporter; Provisional; Region: PRK10504
209261002394	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261002395	putative substrate translocation pore; other site
209261002396	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
209261002397	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
209261002398	Protein export membrane protein; Region: SecD_SecF; cl14618
209261002399	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
209261002400	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
209261002401	HlyD family secretion protein; Region: HlyD_3; pfam13437
209261002402	putative chaperone; Provisional; Region: PRK11678
209261002403	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
209261002404	nucleotide binding site [chemical binding]; other site
209261002405	putative NEF/HSP70 interaction site [polypeptide binding]; other site
209261002406	SBD interface [polypeptide binding]; other site
209261002407	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
209261002408	AlkA N-terminal domain; Region: AlkA_N; pfam06029
209261002409	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
209261002410	minor groove reading motif; other site
209261002411	helix-hairpin-helix signature motif; other site
209261002412	substrate binding pocket [chemical binding]; other site
209261002413	active site
209261002414	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
209261002415	PAS domain S-box; Region: sensory_box; TIGR00229
209261002416	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
209261002417	putative active site [active]
209261002418	heme pocket [chemical binding]; other site
209261002419	PAS domain S-box; Region: sensory_box; TIGR00229
209261002420	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
209261002421	putative active site [active]
209261002422	heme pocket [chemical binding]; other site
209261002423	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
209261002424	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
209261002425	metal binding site [ion binding]; metal-binding site
209261002426	active site
209261002427	I-site; other site
209261002428	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261002429	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
209261002430	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
209261002431	ATP-binding site [chemical binding]; other site
209261002432	Sugar specificity; other site
209261002433	Pyrimidine base specificity; other site
209261002434	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
209261002435	trimer interface [polypeptide binding]; other site
209261002436	active site
209261002437	putative assembly protein; Provisional; Region: PRK10833
209261002438	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
209261002439	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
209261002440	FOG: CBS domain [General function prediction only]; Region: COG0517
209261002441	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
209261002442	Transporter associated domain; Region: CorC_HlyC; smart01091
209261002443	polysaccharide export protein Wza; Provisional; Region: PRK15078
209261002444	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
209261002445	Low molecular weight phosphatase family; Region: LMWPc; cd00115
209261002446	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
209261002447	active site
209261002448	tyrosine kinase; Provisional; Region: PRK11519
209261002449	Chain length determinant protein; Region: Wzz; pfam02706
209261002450	Chain length determinant protein; Region: Wzz; cl15801
209261002451	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
209261002452	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
209261002453	putative glycosyl transferase; Provisional; Region: PRK10018
209261002454	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
209261002455	active site
209261002456	putative acyl transferase; Provisional; Region: PRK10191
209261002457	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
209261002458	trimer interface [polypeptide binding]; other site
209261002459	active site
209261002460	substrate binding site [chemical binding]; other site
209261002461	CoA binding site [chemical binding]; other site
209261002462	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
209261002463	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
209261002464	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
209261002465	putative glycosyl transferase; Provisional; Region: PRK10063
209261002466	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
209261002467	metal-binding site
209261002468	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
209261002469	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
209261002470	putative trimer interface [polypeptide binding]; other site
209261002471	putative active site [active]
209261002472	putative substrate binding site [chemical binding]; other site
209261002473	putative CoA binding site [chemical binding]; other site
209261002474	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
209261002475	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
209261002476	NADP-binding site; other site
209261002477	homotetramer interface [polypeptide binding]; other site
209261002478	substrate binding site [chemical binding]; other site
209261002479	homodimer interface [polypeptide binding]; other site
209261002480	active site
209261002481	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
209261002482	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
209261002483	NADP binding site [chemical binding]; other site
209261002484	active site
209261002485	putative substrate binding site [chemical binding]; other site
209261002486	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
209261002487	active site
209261002488	GDP-Mannose binding site [chemical binding]; other site
209261002489	dimer interface [polypeptide binding]; other site
209261002490	modified nudix motif
209261002491	metal binding site [ion binding]; metal-binding site
209261002492	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
209261002493	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
209261002494	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
209261002495	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
209261002496	Substrate binding site; other site
209261002497	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
209261002498	phosphomannomutase CpsG; Provisional; Region: PRK15414
209261002499	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
209261002500	active site
209261002501	substrate binding site [chemical binding]; other site
209261002502	metal binding site [ion binding]; metal-binding site
209261002503	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
209261002504	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
209261002505	colanic acid exporter; Provisional; Region: PRK10459
209261002506	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
209261002507	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
209261002508	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
209261002509	putative ADP-binding pocket [chemical binding]; other site
209261002510	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
209261002511	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
209261002512	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
209261002513	active site
209261002514	tetramer interface; other site
209261002515	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
209261002516	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
209261002517	NAD binding site [chemical binding]; other site
209261002518	substrate binding site [chemical binding]; other site
209261002519	homodimer interface [polypeptide binding]; other site
209261002520	active site
209261002521	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
209261002522	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
209261002523	NADP binding site [chemical binding]; other site
209261002524	active site
209261002525	putative substrate binding site [chemical binding]; other site
209261002526	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
209261002527	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
209261002528	substrate binding site; other site
209261002529	tetramer interface; other site
209261002530	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
209261002531	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
209261002532	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
209261002533	catalytic loop [active]
209261002534	iron binding site [ion binding]; other site
209261002535	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
209261002536	FAD binding pocket [chemical binding]; other site
209261002537	FAD binding motif [chemical binding]; other site
209261002538	phosphate binding motif [ion binding]; other site
209261002539	beta-alpha-beta structure motif; other site
209261002540	NAD binding pocket [chemical binding]; other site
209261002541	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
209261002542	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
209261002543	substrate binding site; other site
209261002544	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
209261002545	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
209261002546	NAD binding site [chemical binding]; other site
209261002547	homotetramer interface [polypeptide binding]; other site
209261002548	homodimer interface [polypeptide binding]; other site
209261002549	substrate binding site [chemical binding]; other site
209261002550	active site
209261002551	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
209261002552	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
209261002553	inhibitor-cofactor binding pocket; inhibition site
209261002554	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261002555	catalytic residue [active]
209261002556	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
209261002557	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
209261002558	NAD(P) binding site [chemical binding]; other site
209261002559	active site
209261002560	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
209261002561	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
209261002562	NAD binding site [chemical binding]; other site
209261002563	homotetramer interface [polypeptide binding]; other site
209261002564	homodimer interface [polypeptide binding]; other site
209261002565	active site
209261002566	substrate binding site [chemical binding]; other site
209261002567	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
209261002568	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
209261002569	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
209261002570	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
209261002571	active site
209261002572	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
209261002573	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
209261002574	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
209261002575	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
209261002576	active site
209261002577	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
209261002578	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
209261002579	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
209261002580	Substrate binding site; other site
209261002581	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
209261002582	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
209261002583	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
209261002584	active site
209261002585	substrate binding site [chemical binding]; other site
209261002586	metal binding site [ion binding]; metal-binding site
209261002587	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
209261002588	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
209261002589	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
209261002590	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
209261002591	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
209261002592	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
209261002593	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
209261002594	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
209261002595	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
209261002596	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
209261002597	chain length determinant protein WzzB; Provisional; Region: PRK15471
209261002598	Chain length determinant protein; Region: Wzz; cl15801
209261002599	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
209261002600	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
209261002601	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
209261002602	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
209261002603	metal binding site [ion binding]; metal-binding site
209261002604	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
209261002605	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
209261002606	substrate binding site [chemical binding]; other site
209261002607	glutamase interaction surface [polypeptide binding]; other site
209261002608	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
209261002609	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
209261002610	catalytic residues [active]
209261002611	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
209261002612	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
209261002613	putative active site [active]
209261002614	oxyanion strand; other site
209261002615	catalytic triad [active]
209261002616	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
209261002617	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261002618	active site
209261002619	motif I; other site
209261002620	motif II; other site
209261002621	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
209261002622	putative active site pocket [active]
209261002623	4-fold oligomerization interface [polypeptide binding]; other site
209261002624	metal binding residues [ion binding]; metal-binding site
209261002625	3-fold/trimer interface [polypeptide binding]; other site
209261002626	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
209261002627	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261002628	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261002629	homodimer interface [polypeptide binding]; other site
209261002630	catalytic residue [active]
209261002631	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
209261002632	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
209261002633	NAD binding site [chemical binding]; other site
209261002634	dimerization interface [polypeptide binding]; other site
209261002635	product binding site; other site
209261002636	substrate binding site [chemical binding]; other site
209261002637	zinc binding site [ion binding]; other site
209261002638	catalytic residues [active]
209261002639	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
209261002640	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
209261002641	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
209261002642	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
209261002643	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
209261002644	putative NAD(P) binding site [chemical binding]; other site
209261002645	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261002646	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
209261002647	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
209261002648	dimerization interface [polypeptide binding]; other site
209261002649	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
209261002650	exonuclease I; Provisional; Region: sbcB; PRK11779
209261002651	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
209261002652	active site
209261002653	catalytic site [active]
209261002654	substrate binding site [chemical binding]; other site
209261002655	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
209261002656	thiosulfate reductase PhsA; Provisional; Region: PRK15488
209261002657	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
209261002658	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
209261002659	putative [Fe4-S4] binding site [ion binding]; other site
209261002660	putative molybdopterin cofactor binding site [chemical binding]; other site
209261002661	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
209261002662	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
209261002663	putative molybdopterin cofactor binding site; other site
209261002664	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
209261002665	4Fe-4S binding domain; Region: Fer4; cl02805
209261002666	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
209261002667	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
209261002668	DNA gyrase inhibitor; Provisional; Region: PRK10016
209261002669	Predicted membrane protein [Function unknown]; Region: COG1289
209261002670	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
209261002671	hypothetical protein; Provisional; Region: PRK05423
209261002672	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
209261002673	propionate kinase; Reviewed; Region: PRK12397
209261002674	propionate/acetate kinase; Provisional; Region: PRK12379
209261002675	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
209261002676	G3 box; other site
209261002677	Switch II region; other site
209261002678	GTP/Mg2+ binding site [chemical binding]; other site
209261002679	G4 box; other site
209261002680	G5 box; other site
209261002681	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
209261002682	putative hexamer interface [polypeptide binding]; other site
209261002683	putative hexagonal pore; other site
209261002684	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
209261002685	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
209261002686	putative hexamer interface [polypeptide binding]; other site
209261002687	putative hexagonal pore; other site
209261002688	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
209261002689	putative hexamer interface [polypeptide binding]; other site
209261002690	putative hexagonal pore; other site
209261002691	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
209261002692	SLBB domain; Region: SLBB; pfam10531
209261002693	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
209261002694	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
209261002695	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
209261002696	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
209261002697	putative active site [active]
209261002698	metal binding site [ion binding]; metal-binding site
209261002699	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
209261002700	putative catalytic cysteine [active]
209261002701	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
209261002702	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
209261002703	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
209261002704	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
209261002705	Propanediol utilisation protein PduL; Region: PduL; pfam06130
209261002706	Propanediol utilisation protein PduL; Region: PduL; pfam06130
209261002707	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
209261002708	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
209261002709	putative hexamer interface [polypeptide binding]; other site
209261002710	putative hexagonal pore; other site
209261002711	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
209261002712	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
209261002713	Hexamer interface [polypeptide binding]; other site
209261002714	Putative hexagonal pore residue; other site
209261002715	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
209261002716	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
209261002717	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
209261002718	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
209261002719	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
209261002720	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
209261002721	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
209261002722	alpha-beta subunit interface [polypeptide binding]; other site
209261002723	alpha-gamma subunit interface [polypeptide binding]; other site
209261002724	active site
209261002725	substrate and K+ binding site; other site
209261002726	K+ binding site [ion binding]; other site
209261002727	cobalamin binding site [chemical binding]; other site
209261002728	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutL; COG4816
209261002729	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
209261002730	putative hexamer interface [polypeptide binding]; other site
209261002731	putative hexagonal pore; other site
209261002732	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
209261002733	putative hexamer interface [polypeptide binding]; other site
209261002734	putative hexagonal pore; other site
209261002735	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
209261002736	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
209261002737	Hexamer interface [polypeptide binding]; other site
209261002738	Putative hexagonal pore residue; other site
209261002739	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
209261002740	amphipathic channel; other site
209261002741	Asn-Pro-Ala signature motifs; other site
209261002742	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
209261002743	Sensory domain found in PocR; Region: PocR; pfam10114
209261002744	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261002745	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
209261002746	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261002747	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
209261002748	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
209261002749	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
209261002750	catalytic triad [active]
209261002751	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
209261002752	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
209261002753	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
209261002754	active site
209261002755	putative homodimer interface [polypeptide binding]; other site
209261002756	SAM binding site [chemical binding]; other site
209261002757	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
209261002758	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261002759	S-adenosylmethionine binding site [chemical binding]; other site
209261002760	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
209261002761	active site
209261002762	SAM binding site [chemical binding]; other site
209261002763	homodimer interface [polypeptide binding]; other site
209261002764	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
209261002765	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
209261002766	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
209261002767	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
209261002768	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
209261002769	active site
209261002770	SAM binding site [chemical binding]; other site
209261002771	homodimer interface [polypeptide binding]; other site
209261002772	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
209261002773	active site
209261002774	SAM binding site [chemical binding]; other site
209261002775	homodimer interface [polypeptide binding]; other site
209261002776	cobalt transport protein CbiN; Provisional; Region: PRK02898
209261002777	cobalt transport protein CbiQ; Provisional; Region: PRK15485
209261002778	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
209261002779	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
209261002780	Walker A/P-loop; other site
209261002781	ATP binding site [chemical binding]; other site
209261002782	Q-loop/lid; other site
209261002783	ABC transporter signature motif; other site
209261002784	Walker B; other site
209261002785	D-loop; other site
209261002786	H-loop/switch region; other site
209261002787	cobyric acid synthase; Provisional; Region: PRK00784
209261002788	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
209261002789	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
209261002790	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
209261002791	catalytic triad [active]
209261002792	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
209261002793	homotrimer interface [polypeptide binding]; other site
209261002794	Walker A motif; other site
209261002795	GTP binding site [chemical binding]; other site
209261002796	Walker B motif; other site
209261002797	cobalamin synthase; Reviewed; Region: cobS; PRK00235
209261002798	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
209261002799	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
209261002800	putative dimer interface [polypeptide binding]; other site
209261002801	active site pocket [active]
209261002802	putative cataytic base [active]
209261002803	L,D-transpeptidase; Provisional; Region: PRK10190
209261002804	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
209261002805	MATE family multidrug exporter; Provisional; Region: PRK10189
209261002806	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
209261002807	similar to hypothetical protein; corresponds to STY2215 from Accession AL513382: Salmonella typhi CT18
209261002808	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
209261002809	AMP nucleosidase; Provisional; Region: PRK08292
209261002810	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
209261002811	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
209261002812	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
209261002813	MobA/MobL family; Region: MobA_MobL; pfam03389
209261002814	Conjugal transfer protein TraD; Region: TraD; pfam06412
209261002815	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
209261002816	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
209261002817	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
209261002818	Restriction endonuclease [Defense mechanisms]; Region: COG3587
209261002819	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261002820	ATP binding site [chemical binding]; other site
209261002821	integrase; Provisional; Region: PRK09692
209261002822	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
209261002823	active site
209261002824	Int/Topo IB signature motif; other site
209261002825	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
209261002826	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
209261002827	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
209261002828	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
209261002829	Catalytic site [active]
209261002830	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
209261002831	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
209261002832	active site
209261002833	DNA binding site [nucleotide binding]
209261002834	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
209261002835	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
209261002836	DNA-binding site [nucleotide binding]; DNA binding site
209261002837	RNA-binding motif; other site
209261002838	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
209261002839	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
209261002840	trimer interface [polypeptide binding]; other site
209261002841	eyelet of channel; other site
209261002842	Serine carboxypeptidase; Region: Peptidase_S10; cl08270
209261002843	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
209261002844	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
209261002845	Zn2+ binding site [ion binding]; other site
209261002846	Mg2+ binding site [ion binding]; other site
209261002847	DNA cytosine methylase; Provisional; Region: PRK10458
209261002848	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
209261002849	cofactor binding site; other site
209261002850	DNA binding site [nucleotide binding]
209261002851	substrate interaction site [chemical binding]; other site
209261002852	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
209261002853	additional DNA contacts [nucleotide binding]; other site
209261002854	mismatch recognition site; other site
209261002855	active site
209261002856	zinc binding site [ion binding]; other site
209261002857	DNA intercalation site [nucleotide binding]; other site
209261002858	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
209261002859	EamA-like transporter family; Region: EamA; pfam00892
209261002860	EamA-like transporter family; Region: EamA; pfam00892
209261002861	Uncharacterized small protein [Function unknown]; Region: COG5475
209261002862	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
209261002863	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
209261002864	metal binding site [ion binding]; metal-binding site
209261002865	active site
209261002866	I-site; other site
209261002867	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
209261002868	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261002869	active site
209261002870	motif I; other site
209261002871	motif II; other site
209261002872	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
209261002873	hypothetical protein; Provisional; Region: PRK10708
209261002874	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
209261002875	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261002876	DNA binding residues [nucleotide binding]
209261002877	dimerization interface [polypeptide binding]; other site
209261002878	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
209261002879	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
209261002880	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
209261002881	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
209261002882	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
209261002883	flagellar motor switch protein; Validated; Region: fliN; PRK05698
209261002884	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
209261002885	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
209261002886	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
209261002887	flagellar hook-length control protein; Provisional; Region: PRK10118
209261002888	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
209261002889	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
209261002890	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
209261002891	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
209261002892	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
209261002893	Walker A motif/ATP binding site; other site
209261002894	Walker B motif; other site
209261002895	flagellar assembly protein H; Validated; Region: fliH; PRK05687
209261002896	Flagellar assembly protein FliH; Region: FliH; pfam02108
209261002897	flagellar motor switch protein FliG; Region: fliG; TIGR00207
209261002898	FliG C-terminal domain; Region: FliG_C; pfam01706
209261002899	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
209261002900	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
209261002901	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
209261002902	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
209261002903	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
209261002904	CPxP  motif; other site
209261002905	putative inner membrane protein; Provisional; Region: PRK11099
209261002906	Sulphur transport; Region: Sulf_transp; pfam04143
209261002907	lipoprotein; Provisional; Region: PRK10397
209261002908	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
209261002909	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
209261002910	active site
209261002911	Na/Ca binding site [ion binding]; other site
209261002912	catalytic site [active]
209261002913	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
209261002914	flagellar protein FliS; Validated; Region: fliS; PRK05685
209261002915	flagellar capping protein; Reviewed; Region: fliD; PRK08032
209261002916	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
209261002917	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
209261002918	flagellin; Validated; Region: PRK08026
209261002919	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
209261002920	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
209261002921	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
209261002922	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
209261002923	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
209261002924	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
209261002925	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
209261002926	DNA binding residues [nucleotide binding]
209261002927	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
209261002928	cystine transporter subunit; Provisional; Region: PRK11260
209261002929	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261002930	substrate binding pocket [chemical binding]; other site
209261002931	membrane-bound complex binding site; other site
209261002932	hinge residues; other site
209261002933	D-cysteine desulfhydrase; Validated; Region: PRK03910
209261002934	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
209261002935	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261002936	catalytic residue [active]
209261002937	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
209261002938	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261002939	dimer interface [polypeptide binding]; other site
209261002940	conserved gate region; other site
209261002941	putative PBP binding loops; other site
209261002942	ABC-ATPase subunit interface; other site
209261002943	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
209261002944	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
209261002945	Walker A/P-loop; other site
209261002946	ATP binding site [chemical binding]; other site
209261002947	Q-loop/lid; other site
209261002948	ABC transporter signature motif; other site
209261002949	Walker B; other site
209261002950	D-loop; other site
209261002951	H-loop/switch region; other site
209261002952	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
209261002953	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
209261002954	Autoinducer binding domain; Region: Autoind_bind; pfam03472
209261002955	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261002956	DNA binding residues [nucleotide binding]
209261002957	dimerization interface [polypeptide binding]; other site
209261002958	hypothetical protein; Provisional; Region: PRK10613
209261002959	response regulator; Provisional; Region: PRK09483
209261002960	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261002961	active site
209261002962	phosphorylation site [posttranslational modification]
209261002963	intermolecular recognition site; other site
209261002964	dimerization interface [polypeptide binding]; other site
209261002965	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261002966	DNA binding residues [nucleotide binding]
209261002967	dimerization interface [polypeptide binding]; other site
209261002968	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
209261002969	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
209261002970	GIY-YIG motif/motif A; other site
209261002971	active site
209261002972	catalytic site [active]
209261002973	putative DNA binding site [nucleotide binding]; other site
209261002974	metal binding site [ion binding]; metal-binding site
209261002975	UvrB/uvrC motif; Region: UVR; pfam02151
209261002976	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
209261002977	Helix-hairpin-helix motif; Region: HHH; pfam00633
209261002978	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
209261002979	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
209261002980	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
209261002981	NlpC/P60 family; Region: NLPC_P60; cl17555
209261002982	hypothetical protein; Provisional; Region: PRK10396
209261002983	yecA family protein; Region: ygfB_yecA; TIGR02292
209261002984	SEC-C motif; Region: SEC-C; pfam02810
209261002985	tyrosine transporter TyrP; Provisional; Region: PRK15132
209261002986	aromatic amino acid transport protein; Region: araaP; TIGR00837
209261002987	probable metal-binding protein; Region: matur_matur; TIGR03853
209261002988	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
209261002989	Ferritin-like domain; Region: Ferritin; pfam00210
209261002990	ferroxidase diiron center [ion binding]; other site
209261002991	YecR-like lipoprotein; Region: YecR; pfam13992
209261002992	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
209261002993	Ferritin-like domain; Region: Ferritin; pfam00210
209261002994	ferroxidase diiron center [ion binding]; other site
209261002995	DJ-1 family protein; Region: not_thiJ; TIGR01383
209261002996	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
209261002997	conserved cys residue [active]
209261002998	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
209261002999	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
209261003000	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
209261003001	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
209261003002	active site
209261003003	homotetramer interface [polypeptide binding]; other site
209261003004	transcriptional activator FlhD; Provisional; Region: PRK02909
209261003005	transcriptional activator FlhC; Provisional; Region: PRK12722
209261003006	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
209261003007	flagellar motor protein MotA; Validated; Region: PRK09110
209261003008	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
209261003009	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
209261003010	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
209261003011	ligand binding site [chemical binding]; other site
209261003012	chemotaxis protein CheA; Provisional; Region: PRK10547
209261003013	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
209261003014	putative binding surface; other site
209261003015	active site
209261003016	CheY binding; Region: CheY-binding; pfam09078
209261003017	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
209261003018	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261003019	ATP binding site [chemical binding]; other site
209261003020	Mg2+ binding site [ion binding]; other site
209261003021	G-X-G motif; other site
209261003022	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
209261003023	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
209261003024	putative CheA interaction surface; other site
209261003025	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
209261003026	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
209261003027	dimer interface [polypeptide binding]; other site
209261003028	ligand binding site [chemical binding]; other site
209261003029	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261003030	dimerization interface [polypeptide binding]; other site
209261003031	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
209261003032	dimer interface [polypeptide binding]; other site
209261003033	putative CheW interface [polypeptide binding]; other site
209261003034	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
209261003035	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
209261003036	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261003037	S-adenosylmethionine binding site [chemical binding]; other site
209261003038	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
209261003039	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261003040	active site
209261003041	phosphorylation site [posttranslational modification]
209261003042	intermolecular recognition site; other site
209261003043	dimerization interface [polypeptide binding]; other site
209261003044	CheB methylesterase; Region: CheB_methylest; pfam01339
209261003045	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
209261003046	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261003047	active site
209261003048	phosphorylation site [posttranslational modification]
209261003049	intermolecular recognition site; other site
209261003050	dimerization interface [polypeptide binding]; other site
209261003051	chemotaxis regulator CheZ; Provisional; Region: PRK11166
209261003052	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
209261003053	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
209261003054	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
209261003055	FHIPEP family; Region: FHIPEP; pfam00771
209261003056	Flagellar protein FlhE; Region: FlhE; pfam06366
209261003057	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
209261003058	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
209261003059	arginyl-tRNA synthetase; Region: argS; TIGR00456
209261003060	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
209261003061	active site
209261003062	HIGH motif; other site
209261003063	KMSK motif region; other site
209261003064	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
209261003065	tRNA binding surface [nucleotide binding]; other site
209261003066	anticodon binding site; other site
209261003067	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
209261003068	putative metal binding site [ion binding]; other site
209261003069	copper homeostasis protein CutC; Provisional; Region: PRK11572
209261003070	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261003071	S-adenosylmethionine binding site [chemical binding]; other site
209261003072	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261003073	S-adenosylmethionine binding site [chemical binding]; other site
209261003074	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
209261003075	hypothetical protein; Provisional; Region: PRK10302
209261003076	Isochorismatase family; Region: Isochorismatase; pfam00857
209261003077	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
209261003078	catalytic triad [active]
209261003079	conserved cis-peptide bond; other site
209261003080	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
209261003081	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
209261003082	dimer interface [polypeptide binding]; other site
209261003083	anticodon binding site; other site
209261003084	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
209261003085	homodimer interface [polypeptide binding]; other site
209261003086	motif 1; other site
209261003087	active site
209261003088	motif 2; other site
209261003089	GAD domain; Region: GAD; pfam02938
209261003090	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
209261003091	active site
209261003092	motif 3; other site
209261003093	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
209261003094	nudix motif; other site
209261003095	hypothetical protein; Validated; Region: PRK00110
209261003096	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
209261003097	active site
209261003098	putative DNA-binding cleft [nucleotide binding]; other site
209261003099	dimer interface [polypeptide binding]; other site
209261003100	hypothetical protein; Provisional; Region: PRK11470
209261003101	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
209261003102	RuvA N terminal domain; Region: RuvA_N; pfam01330
209261003103	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
209261003104	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
209261003105	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261003106	Walker A motif; other site
209261003107	ATP binding site [chemical binding]; other site
209261003108	Walker B motif; other site
209261003109	arginine finger; other site
209261003110	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
209261003111	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
209261003112	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
209261003113	ABC-ATPase subunit  interface; other site
209261003114	dimer interface [polypeptide binding]; other site
209261003115	putative PBP binding regions; other site
209261003116	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
209261003117	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
209261003118	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
209261003119	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
209261003120	metal binding site [ion binding]; metal-binding site
209261003121	putative peptidase; Provisional; Region: PRK11649
209261003122	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
209261003123	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
209261003124	Peptidase family M23; Region: Peptidase_M23; pfam01551
209261003125	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
209261003126	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
209261003127	putative acyl-acceptor binding pocket; other site
209261003128	pyruvate kinase; Provisional; Region: PRK05826
209261003129	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
209261003130	domain interfaces; other site
209261003131	active site
209261003132	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
209261003133	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
209261003134	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
209261003135	putative active site [active]
209261003136	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
209261003137	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
209261003138	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
209261003139	phosphogluconate dehydratase; Validated; Region: PRK09054
209261003140	6-phosphogluconate dehydratase; Region: edd; TIGR01196
209261003141	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
209261003142	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
209261003143	active site
209261003144	intersubunit interface [polypeptide binding]; other site
209261003145	catalytic residue [active]
209261003146	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
209261003147	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
209261003148	ATP-grasp domain; Region: ATP-grasp; pfam02222
209261003149	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
209261003150	hypothetical protein; Provisional; Region: PRK13680
209261003151	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
209261003152	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
209261003153	putative metal binding site [ion binding]; other site
209261003154	protease 2; Provisional; Region: PRK10115
209261003155	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
209261003156	exodeoxyribonuclease X; Provisional; Region: PRK07983
209261003157	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
209261003158	active site
209261003159	catalytic site [active]
209261003160	substrate binding site [chemical binding]; other site
209261003161	Predicted amidohydrolase [General function prediction only]; Region: COG0388
209261003162	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
209261003163	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
209261003164	hypothetical protein; Provisional; Region: PRK10301
209261003165	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
209261003166	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
209261003167	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
209261003168	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
209261003169	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
209261003170	metal binding site [ion binding]; metal-binding site
209261003171	active site
209261003172	I-site; other site
209261003173	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
209261003174	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
209261003175	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
209261003176	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
209261003177	EamA-like transporter family; Region: EamA; pfam00892
209261003178	EamA-like transporter family; Region: EamA; pfam00892
209261003179	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
209261003180	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261003181	Coenzyme A binding pocket [chemical binding]; other site
209261003182	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
209261003183	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
209261003184	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
209261003185	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
209261003186	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
209261003187	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
209261003188	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
209261003189	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
209261003190	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
209261003191	mce related protein; Region: MCE; pfam02470
209261003192	mce related protein; Region: MCE; pfam02470
209261003193	mce related protein; Region: MCE; pfam02470
209261003194	mce related protein; Region: MCE; pfam02470
209261003195	mce related protein; Region: MCE; pfam02470
209261003196	mce related protein; Region: MCE; pfam02470
209261003197	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
209261003198	Paraquat-inducible protein A; Region: PqiA; pfam04403
209261003199	Paraquat-inducible protein A; Region: PqiA; pfam04403
209261003200	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
209261003201	GAF domain; Region: GAF_2; pfam13185
209261003202	ProP expression regulator; Provisional; Region: PRK04950
209261003203	ProQ/FINO family; Region: ProQ; pfam04352
209261003204	carboxy-terminal protease; Provisional; Region: PRK11186
209261003205	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
209261003206	protein binding site [polypeptide binding]; other site
209261003207	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
209261003208	Catalytic dyad [active]
209261003209	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
209261003210	heat shock protein HtpX; Provisional; Region: PRK05457
209261003211	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
209261003212	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
209261003213	dimerization interface [polypeptide binding]; other site
209261003214	putative Zn2+ binding site [ion binding]; other site
209261003215	putative DNA binding site [nucleotide binding]; other site
209261003216	Bacterial transcriptional regulator; Region: IclR; pfam01614
209261003217	YobH-like protein; Region: YobH; pfam13996
209261003218	PhoPQ regulatory protein; Provisional; Region: PRK10299
209261003219	YebO-like protein; Region: YebO; pfam13974
209261003220	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
209261003221	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
209261003222	DNA-binding site [nucleotide binding]; DNA binding site
209261003223	RNA-binding motif; other site
209261003224	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
209261003225	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
209261003226	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
209261003227	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
209261003228	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261003229	S-adenosylmethionine binding site [chemical binding]; other site
209261003230	hypothetical protein; Provisional; Region: PRK11469
209261003231	Domain of unknown function DUF; Region: DUF204; pfam02659
209261003232	Domain of unknown function DUF; Region: DUF204; pfam02659
209261003233	hypothetical protein; Provisional; Region: PRK02913
209261003234	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
209261003235	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
209261003236	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
209261003237	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
209261003238	active pocket/dimerization site; other site
209261003239	active site
209261003240	phosphorylation site [posttranslational modification]
209261003241	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
209261003242	active site
209261003243	phosphorylation site [posttranslational modification]
209261003244	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
209261003245	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
209261003246	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
209261003247	Transporter associated domain; Region: CorC_HlyC; smart01091
209261003248	phage resistance protein; Provisional; Region: PRK10551
209261003249	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
209261003250	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261003251	L-serine deaminase; Provisional; Region: PRK15023
209261003252	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
209261003253	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
209261003254	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
209261003255	putative active site [active]
209261003256	putative CoA binding site [chemical binding]; other site
209261003257	nudix motif; other site
209261003258	metal binding site [ion binding]; metal-binding site
209261003259	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
209261003260	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
209261003261	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
209261003262	hypothetical protein; Provisional; Region: PRK05114
209261003263	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
209261003264	homotrimer interaction site [polypeptide binding]; other site
209261003265	putative active site [active]
209261003266	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
209261003267	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
209261003268	DEAD_2; Region: DEAD_2; pfam06733
209261003269	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
209261003270	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
209261003271	Glycoprotease family; Region: Peptidase_M22; pfam00814
209261003272	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
209261003273	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
209261003274	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
209261003275	acyl-activating enzyme (AAE) consensus motif; other site
209261003276	putative AMP binding site [chemical binding]; other site
209261003277	putative active site [active]
209261003278	putative CoA binding site [chemical binding]; other site
209261003279	ribonuclease D; Provisional; Region: PRK10829
209261003280	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
209261003281	catalytic site [active]
209261003282	putative active site [active]
209261003283	putative substrate binding site [chemical binding]; other site
209261003284	HRDC domain; Region: HRDC; cl02578
209261003285	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
209261003286	cell division inhibitor MinD; Provisional; Region: PRK10818
209261003287	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
209261003288	Switch I; other site
209261003289	Switch II; other site
209261003290	septum formation inhibitor; Reviewed; Region: minC; PRK03511
209261003291	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
209261003292	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
209261003293	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
209261003294	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
209261003295	hypothetical protein; Provisional; Region: PRK10691
209261003296	hypothetical protein; Provisional; Region: PRK05170
209261003297	GnsA/GnsB family; Region: GnsAB; pfam08178
209261003298	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
209261003299	disulfide bond formation protein B; Provisional; Region: PRK01749
209261003300	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
209261003301	transmembrane helices; other site
209261003302	fatty acid metabolism regulator; Provisional; Region: PRK04984
209261003303	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261003304	DNA-binding site [nucleotide binding]; DNA binding site
209261003305	FadR C-terminal domain; Region: FadR_C; pfam07840
209261003306	SpoVR family protein; Provisional; Region: PRK11767
209261003307	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
209261003308	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
209261003309	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
209261003310	alanine racemase; Reviewed; Region: dadX; PRK03646
209261003311	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
209261003312	active site
209261003313	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
209261003314	substrate binding site [chemical binding]; other site
209261003315	catalytic residues [active]
209261003316	dimer interface [polypeptide binding]; other site
209261003317	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
209261003318	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
209261003319	TrkA-C domain; Region: TrkA_C; pfam02080
209261003320	Transporter associated domain; Region: CorC_HlyC; smart01091
209261003321	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
209261003322	dimer interface [polypeptide binding]; other site
209261003323	catalytic triad [active]
209261003324	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
209261003325	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
209261003326	N-acetyl-D-glucosamine binding site [chemical binding]; other site
209261003327	catalytic residue [active]
209261003328	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
209261003329	Flagellar regulator YcgR; Region: YcgR; pfam07317
209261003330	PilZ domain; Region: PilZ; pfam07238
209261003331	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
209261003332	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
209261003333	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
209261003334	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
209261003335	NAD(P) binding site [chemical binding]; other site
209261003336	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
209261003337	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
209261003338	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
209261003339	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
209261003340	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
209261003341	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
209261003342	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
209261003343	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
209261003344	putative substrate-binding site; other site
209261003345	nickel binding site [ion binding]; other site
209261003346	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
209261003347	hydrogenase 1 large subunit; Provisional; Region: PRK10170
209261003348	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
209261003349	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
209261003350	Protein of unknown function (DUF4427); Region: DUF4427; pfam14468
209261003351	GTP-binding protein YchF; Reviewed; Region: PRK09601
209261003352	YchF GTPase; Region: YchF; cd01900
209261003353	G1 box; other site
209261003354	GTP/Mg2+ binding site [chemical binding]; other site
209261003355	Switch I region; other site
209261003356	G2 box; other site
209261003357	Switch II region; other site
209261003358	G3 box; other site
209261003359	G4 box; other site
209261003360	G5 box; other site
209261003361	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
209261003362	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
209261003363	putative active site [active]
209261003364	catalytic residue [active]
209261003365	hypothetical protein; Provisional; Region: PRK10692
209261003366	putative transporter; Provisional; Region: PRK11660
209261003367	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
209261003368	Sulfate transporter family; Region: Sulfate_transp; pfam00916
209261003369	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
209261003370	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
209261003371	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
209261003372	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
209261003373	active site
209261003374	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
209261003375	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
209261003376	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
209261003377	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
209261003378	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
209261003379	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
209261003380	tRNA; other site
209261003381	putative tRNA binding site [nucleotide binding]; other site
209261003382	putative NADP binding site [chemical binding]; other site
209261003383	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
209261003384	peptide chain release factor 1; Validated; Region: prfA; PRK00591
209261003385	This domain is found in peptide chain release factors; Region: PCRF; smart00937
209261003386	RF-1 domain; Region: RF-1; pfam00472
209261003387	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
209261003388	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261003389	hypothetical protein; Provisional; Region: PRK10278
209261003390	hypothetical protein; Provisional; Region: PRK10941
209261003391	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
209261003392	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
209261003393	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
209261003394	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261003395	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
209261003396	subtilase cytotoxin subunit B; Provisional; Region: PRK15266
209261003397	pertussis toxin-like subunit ArtA; Provisional; Region: PRK15272
209261003398	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
209261003399	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
209261003400	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
209261003401	Protein of unknown function (DUF1353); Region: DUF1353; pfam07087
209261003402	CdtB, the catalytic DNase I-like subunit of cytolethal distending toxin (CDT) protein; Region: CdtB; cd09081
209261003403	putative catalytic site [active]
209261003404	CdtC interface [polypeptide binding]; other site
209261003405	heterotrimer interface [polypeptide binding]; other site
209261003406	CdtA interface [polypeptide binding]; other site
209261003407	putative metal binding site [ion binding]; other site
209261003408	putative phosphate binding site [ion binding]; other site
209261003409	DinI-like family; Region: DinI; pfam06183
209261003410	Ricin-type beta-trefoil; Region: RICIN; smart00458
209261003411	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
209261003412	putative sugar binding sites [chemical binding]; other site
209261003413	Q-X-W motif; other site
209261003414	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
209261003415	DNA-binding site [nucleotide binding]; DNA binding site
209261003416	RNA-binding motif; other site
209261003417	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
209261003418	lysozyme inhibitor; Provisional; Region: PRK13791
209261003419	similar to hypothetical protein; corresponds to STY1874B from Accession AL513382: Salmonella typhi CT18
209261003420	similar to hypothetical protein; corresponds to STY1874A from Accession AL513382: Salmonella typhi CT18
209261003421	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
209261003422	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
209261003423	putative dimer interface [polypeptide binding]; other site
209261003424	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
209261003425	BNR repeat-like domain; Region: BNR_2; pfam13088
209261003426	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
209261003427	TRL-like protein family; Region: TRL; pfam13146
209261003428	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
209261003429	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
209261003430	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
209261003431	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261003432	dimer interface [polypeptide binding]; other site
209261003433	conserved gate region; other site
209261003434	ABC-ATPase subunit interface; other site
209261003435	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
209261003436	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261003437	dimer interface [polypeptide binding]; other site
209261003438	conserved gate region; other site
209261003439	putative PBP binding loops; other site
209261003440	ABC-ATPase subunit interface; other site
209261003441	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261003442	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
209261003443	Walker A/P-loop; other site
209261003444	ATP binding site [chemical binding]; other site
209261003445	Q-loop/lid; other site
209261003446	ABC transporter signature motif; other site
209261003447	Walker B; other site
209261003448	D-loop; other site
209261003449	H-loop/switch region; other site
209261003450	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261003451	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
209261003452	Walker A/P-loop; other site
209261003453	ATP binding site [chemical binding]; other site
209261003454	Q-loop/lid; other site
209261003455	ABC transporter signature motif; other site
209261003456	Walker B; other site
209261003457	D-loop; other site
209261003458	H-loop/switch region; other site
209261003459	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
209261003460	Mechanosensitive ion channel; Region: MS_channel; pfam00924
209261003461	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
209261003462	dimerization interface [polypeptide binding]; other site
209261003463	zinc/cadmium-binding protein; Provisional; Region: PRK10306
209261003464	aminoglycoside resistance protein; Provisional; Region: PRK13746
209261003465	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
209261003466	active site
209261003467	NTP binding site [chemical binding]; other site
209261003468	metal binding triad [ion binding]; metal-binding site
209261003469	antibiotic binding site [chemical binding]; other site
209261003470	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
209261003471	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261003472	DNA binding residues [nucleotide binding]
209261003473	transcriptional regulator MirA; Provisional; Region: PRK15043
209261003474	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
209261003475	DNA binding residues [nucleotide binding]
209261003476	dimer interface [polypeptide binding]; other site
209261003477	Pleckstrin homology-like domain; Region: PH-like; cl17171
209261003478	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
209261003479	chorismate mutase; Provisional; Region: PRK08055
209261003480	leucine export protein LeuE; Provisional; Region: PRK10958
209261003481	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
209261003482	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
209261003483	Phage Tail Collar Domain; Region: Collar; pfam07484
209261003484	hypothetical protein; Provisional; Region: PRK10457
209261003485	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261003486	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
209261003487	murein hydrolase B; Provisional; Region: PRK10760; cl17906
209261003488	Domain of unknown function (DUF333); Region: DUF333; pfam03891
209261003489	Uncharacterized conserved protein [Function unknown]; Region: COG3189
209261003490	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
209261003491	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261003492	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
209261003493	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261003494	Predicted membrane protein [Function unknown]; Region: COG2707
209261003495	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
209261003496	putative deacylase active site [active]
209261003497	hypothetical protein; Provisional; Region: PRK05325
209261003498	PrkA family serine protein kinase; Provisional; Region: PRK15455
209261003499	AAA ATPase domain; Region: AAA_16; pfam13191
209261003500	Walker A motif; other site
209261003501	ATP binding site [chemical binding]; other site
209261003502	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
209261003503	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
209261003504	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
209261003505	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
209261003506	active site
209261003507	catalytic tetrad [active]
209261003508	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
209261003509	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
209261003510	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
209261003511	methionine sulfoxide reductase B; Provisional; Region: PRK00222
209261003512	SelR domain; Region: SelR; pfam01641
209261003513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
209261003514	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
209261003515	Isochorismatase family; Region: Isochorismatase; pfam00857
209261003516	catalytic triad [active]
209261003517	metal binding site [ion binding]; metal-binding site
209261003518	conserved cis-peptide bond; other site
209261003519	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
209261003520	active site
209261003521	homodimer interface [polypeptide binding]; other site
209261003522	protease 4; Provisional; Region: PRK10949
209261003523	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
209261003524	tandem repeat interface [polypeptide binding]; other site
209261003525	oligomer interface [polypeptide binding]; other site
209261003526	active site residues [active]
209261003527	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
209261003528	tandem repeat interface [polypeptide binding]; other site
209261003529	oligomer interface [polypeptide binding]; other site
209261003530	active site residues [active]
209261003531	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
209261003532	putative FMN binding site [chemical binding]; other site
209261003533	selenophosphate synthetase; Provisional; Region: PRK00943
209261003534	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
209261003535	dimerization interface [polypeptide binding]; other site
209261003536	putative ATP binding site [chemical binding]; other site
209261003537	DNA topoisomerase III; Provisional; Region: PRK07726
209261003538	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
209261003539	active site
209261003540	putative interdomain interaction site [polypeptide binding]; other site
209261003541	putative metal-binding site [ion binding]; other site
209261003542	putative nucleotide binding site [chemical binding]; other site
209261003543	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
209261003544	domain I; other site
209261003545	DNA binding groove [nucleotide binding]
209261003546	phosphate binding site [ion binding]; other site
209261003547	domain II; other site
209261003548	domain III; other site
209261003549	nucleotide binding site [chemical binding]; other site
209261003550	catalytic site [active]
209261003551	domain IV; other site
209261003552	glutamate dehydrogenase; Provisional; Region: PRK09414
209261003553	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
209261003554	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
209261003555	NAD(P) binding site [chemical binding]; other site
209261003556	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
209261003557	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
209261003558	active site
209261003559	8-oxo-dGMP binding site [chemical binding]; other site
209261003560	nudix motif; other site
209261003561	metal binding site [ion binding]; metal-binding site
209261003562	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
209261003563	putative catalytic site [active]
209261003564	putative phosphate binding site [ion binding]; other site
209261003565	active site
209261003566	metal binding site A [ion binding]; metal-binding site
209261003567	DNA binding site [nucleotide binding]
209261003568	putative AP binding site [nucleotide binding]; other site
209261003569	putative metal binding site B [ion binding]; other site
209261003570	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
209261003571	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
209261003572	inhibitor-cofactor binding pocket; inhibition site
209261003573	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261003574	catalytic residue [active]
209261003575	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
209261003576	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
209261003577	NAD(P) binding site [chemical binding]; other site
209261003578	catalytic residues [active]
209261003579	succinylarginine dihydrolase; Provisional; Region: PRK13281
209261003580	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
209261003581	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
209261003582	putative active site [active]
209261003583	Zn binding site [ion binding]; other site
209261003584	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
209261003585	dimer interface [polypeptide binding]; other site
209261003586	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
209261003587	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
209261003588	GIY-YIG motif/motif A; other site
209261003589	active site
209261003590	catalytic site [active]
209261003591	putative DNA binding site [nucleotide binding]; other site
209261003592	metal binding site [ion binding]; metal-binding site
209261003593	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
209261003594	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
209261003595	homodimer interface [polypeptide binding]; other site
209261003596	NAD binding pocket [chemical binding]; other site
209261003597	ATP binding pocket [chemical binding]; other site
209261003598	Mg binding site [ion binding]; other site
209261003599	active-site loop [active]
209261003600	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
209261003601	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
209261003602	active site
209261003603	P-loop; other site
209261003604	phosphorylation site [posttranslational modification]
209261003605	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
209261003606	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
209261003607	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
209261003608	methionine cluster; other site
209261003609	active site
209261003610	phosphorylation site [posttranslational modification]
209261003611	metal binding site [ion binding]; metal-binding site
209261003612	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
209261003613	Cupin domain; Region: Cupin_2; pfam07883
209261003614	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261003615	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
209261003616	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
209261003617	NAD binding site [chemical binding]; other site
209261003618	sugar binding site [chemical binding]; other site
209261003619	divalent metal binding site [ion binding]; other site
209261003620	tetramer (dimer of dimers) interface [polypeptide binding]; other site
209261003621	dimer interface [polypeptide binding]; other site
209261003622	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
209261003623	putative active site [active]
209261003624	YdjC motif; other site
209261003625	Mg binding site [ion binding]; other site
209261003626	putative homodimer interface [polypeptide binding]; other site
209261003627	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261003628	hydroperoxidase II; Provisional; Region: katE; PRK11249
209261003629	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
209261003630	tetramer interface [polypeptide binding]; other site
209261003631	heme binding pocket [chemical binding]; other site
209261003632	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
209261003633	domain interactions; other site
209261003634	cell division modulator; Provisional; Region: PRK10113
209261003635	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
209261003636	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
209261003637	inner membrane protein; Provisional; Region: PRK11648
209261003638	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
209261003639	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
209261003640	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261003641	motif II; other site
209261003642	YniB-like protein; Region: YniB; pfam14002
209261003643	Phosphotransferase enzyme family; Region: APH; pfam01636
209261003644	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
209261003645	active site
209261003646	ATP binding site [chemical binding]; other site
209261003647	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
209261003648	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
209261003649	6-phosphofructokinase 2; Provisional; Region: PRK10294
209261003650	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
209261003651	putative substrate binding site [chemical binding]; other site
209261003652	putative ATP binding site [chemical binding]; other site
209261003653	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
209261003654	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
209261003655	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
209261003656	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
209261003657	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
209261003658	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
209261003659	active site
209261003660	dimer interface [polypeptide binding]; other site
209261003661	motif 1; other site
209261003662	motif 2; other site
209261003663	motif 3; other site
209261003664	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
209261003665	anticodon binding site; other site
209261003666	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
209261003667	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
209261003668	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
209261003669	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
209261003670	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
209261003671	23S rRNA binding site [nucleotide binding]; other site
209261003672	L21 binding site [polypeptide binding]; other site
209261003673	L13 binding site [polypeptide binding]; other site
209261003674	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
209261003675	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
209261003676	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
209261003677	dimer interface [polypeptide binding]; other site
209261003678	motif 1; other site
209261003679	active site
209261003680	motif 2; other site
209261003681	motif 3; other site
209261003682	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
209261003683	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
209261003684	putative tRNA-binding site [nucleotide binding]; other site
209261003685	B3/4 domain; Region: B3_4; pfam03483
209261003686	tRNA synthetase B5 domain; Region: B5; smart00874
209261003687	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
209261003688	dimer interface [polypeptide binding]; other site
209261003689	motif 1; other site
209261003690	motif 3; other site
209261003691	motif 2; other site
209261003692	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
209261003693	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
209261003694	IHF dimer interface [polypeptide binding]; other site
209261003695	IHF - DNA interface [nucleotide binding]; other site
209261003696	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
209261003697	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
209261003698	ABC-ATPase subunit  interface; other site
209261003699	dimer interface [polypeptide binding]; other site
209261003700	putative PBP binding regions; other site
209261003701	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
209261003702	catalytic residues [active]
209261003703	dimer interface [polypeptide binding]; other site
209261003704	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
209261003705	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
209261003706	Walker A/P-loop; other site
209261003707	ATP binding site [chemical binding]; other site
209261003708	Q-loop/lid; other site
209261003709	ABC transporter signature motif; other site
209261003710	Walker B; other site
209261003711	D-loop; other site
209261003712	H-loop/switch region; other site
209261003713	NlpC/P60 family; Region: NLPC_P60; pfam00877
209261003714	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
209261003715	Uncharacterized conserved protein [Function unknown]; Region: COG0397
209261003716	hypothetical protein; Validated; Region: PRK00029
209261003717	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
209261003718	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
209261003719	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
209261003720	PEP synthetase regulatory protein; Provisional; Region: PRK05339
209261003721	phosphoenolpyruvate synthase; Validated; Region: PRK06464
209261003722	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
209261003723	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
209261003724	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
209261003725	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
209261003726	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
209261003727	active site
209261003728	catalytic residue [active]
209261003729	dimer interface [polypeptide binding]; other site
209261003730	putative inner membrane protein; Provisional; Region: PRK10983
209261003731	Domain of unknown function DUF20; Region: UPF0118; pfam01594
209261003732	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
209261003733	FAD binding domain; Region: FAD_binding_4; pfam01565
209261003734	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
209261003735	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
209261003736	CoenzymeA binding site [chemical binding]; other site
209261003737	subunit interaction site [polypeptide binding]; other site
209261003738	PHB binding site; other site
209261003739	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
209261003740	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
209261003741	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
209261003742	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
209261003743	putative ABC transporter; Region: ycf24; CHL00085
209261003744	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
209261003745	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
209261003746	Walker A/P-loop; other site
209261003747	ATP binding site [chemical binding]; other site
209261003748	Q-loop/lid; other site
209261003749	ABC transporter signature motif; other site
209261003750	Walker B; other site
209261003751	D-loop; other site
209261003752	H-loop/switch region; other site
209261003753	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
209261003754	FeS assembly protein SufD; Region: sufD; TIGR01981
209261003755	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
209261003756	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
209261003757	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
209261003758	catalytic residue [active]
209261003759	cysteine desufuration protein SufE; Provisional; Region: PRK09296
209261003760	murein lipoprotein; Provisional; Region: PRK15396
209261003761	murein lipoprotein; Provisional; Region: PRK15396
209261003762	pyruvate kinase; Provisional; Region: PRK09206
209261003763	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
209261003764	domain interfaces; other site
209261003765	active site
209261003766	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
209261003767	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
209261003768	tetrathionate reductase subunit A; Provisional; Region: PRK14991
209261003769	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
209261003770	putative [Fe4-S4] binding site [ion binding]; other site
209261003771	putative molybdopterin cofactor binding site [chemical binding]; other site
209261003772	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
209261003773	putative molybdopterin cofactor binding site; other site
209261003774	tetrathionate reductase subunit C; Provisional; Region: PRK14992
209261003775	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
209261003776	tetrathionate reductase subunit B; Provisional; Region: PRK14993
209261003777	4Fe-4S binding domain; Region: Fer4; pfam00037
209261003778	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
209261003779	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
209261003780	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
209261003781	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261003782	dimer interface [polypeptide binding]; other site
209261003783	phosphorylation site [posttranslational modification]
209261003784	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261003785	ATP binding site [chemical binding]; other site
209261003786	Mg2+ binding site [ion binding]; other site
209261003787	G-X-G motif; other site
209261003788	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
209261003789	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261003790	active site
209261003791	phosphorylation site [posttranslational modification]
209261003792	intermolecular recognition site; other site
209261003793	dimerization interface [polypeptide binding]; other site
209261003794	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261003795	DNA binding residues [nucleotide binding]
209261003796	dimerization interface [polypeptide binding]; other site
209261003797	hypothetical protein; Provisional; Region: PRK10292
209261003798	Uncharacterized conserved protein [Function unknown]; Region: COG1683
209261003799	Uncharacterized conserved protein [Function unknown]; Region: COG3272
209261003800	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
209261003801	transcriptional regulator MirA; Provisional; Region: PRK15043
209261003802	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
209261003803	DNA binding residues [nucleotide binding]
209261003804	two component system sensor kinase SsrB; Provisional; Region: PRK15369
209261003805	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261003806	active site
209261003807	phosphorylation site [posttranslational modification]
209261003808	intermolecular recognition site; other site
209261003809	dimerization interface [polypeptide binding]; other site
209261003810	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261003811	DNA binding residues [nucleotide binding]
209261003812	dimerization interface [polypeptide binding]; other site
209261003813	two component system sensor kinase SsrA; Provisional; Region: PRK15347
209261003814	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261003815	dimerization interface [polypeptide binding]; other site
209261003816	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261003817	dimer interface [polypeptide binding]; other site
209261003818	phosphorylation site [posttranslational modification]
209261003819	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261003820	ATP binding site [chemical binding]; other site
209261003821	Mg2+ binding site [ion binding]; other site
209261003822	G-X-G motif; other site
209261003823	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261003824	active site
209261003825	phosphorylation site [posttranslational modification]
209261003826	intermolecular recognition site; other site
209261003827	dimerization interface [polypeptide binding]; other site
209261003828	pathogenicity island chaperone protein SpiC; Provisional; Region: PRK15368
209261003829	outer membrane secretin SsaC; Provisional; Region: PRK15346
209261003830	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
209261003831	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
209261003832	type III secretion system protein SsaD; Provisional; Region: PRK15367
209261003833	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
209261003834	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
209261003835	type III secretion system chaperone SseA; Provisional; Region: PRK15365
209261003836	pathogenicity island 2 effector protein SseB; Provisional; Region: PRK15364
209261003837	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
209261003838	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
209261003839	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
209261003840	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
209261003841	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
209261003842	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
209261003843	TPR motif; other site
209261003844	binding surface
209261003845	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
209261003846	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
209261003847	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
209261003848	type III secretion system protein SsaH; Provisional; Region: PRK15356
209261003849	type III secretion system protein SsaI; Provisional; Region: PRK15355
209261003850	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
209261003851	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
209261003852	type III secretion system protein SsaK; Provisional; Region: PRK15354
209261003853	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
209261003854	type III secretion system protein SsaL; Provisional; Region: PRK15345
209261003855	HrpJ-like domain; Region: HrpJ; pfam07201
209261003856	TyeA; Region: TyeA; cl07611
209261003857	type III secretion system protein SsaM; Provisional; Region: PRK15353
209261003858	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
209261003859	FHIPEP family; Region: FHIPEP; pfam00771
209261003860	type III secretion system ATPase SsaN; Validated; Region: PRK07594
209261003861	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
209261003862	Walker A motif; other site
209261003863	ATP binding site [chemical binding]; other site
209261003864	Walker B motif; other site
209261003865	type III secretion system protein SsaO; Provisional; Region: PRK15352
209261003866	type III secretion system protein SsaP; Provisional; Region: PRK15351
209261003867	type III secretion system protein SsaQ; Validated; Region: PRK08035
209261003868	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
209261003869	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
209261003870	type III secretion system protein SsaS; Provisional; Region: PRK15350
209261003871	type III secretion system protein SsaT; Provisional; Region: PRK15349
209261003872	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
209261003873	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
209261003874	multidrug efflux protein; Reviewed; Region: PRK01766
209261003875	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
209261003876	cation binding site [ion binding]; other site
209261003877	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
209261003878	Lumazine binding domain; Region: Lum_binding; pfam00677
209261003879	Lumazine binding domain; Region: Lum_binding; pfam00677
209261003880	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
209261003881	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261003882	S-adenosylmethionine binding site [chemical binding]; other site
209261003883	putative transporter; Provisional; Region: PRK11043
209261003884	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261003885	putative substrate translocation pore; other site
209261003886	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
209261003887	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261003888	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
209261003889	dimerization interface [polypeptide binding]; other site
209261003890	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
209261003891	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261003892	DNA binding site [nucleotide binding]
209261003893	domain linker motif; other site
209261003894	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
209261003895	dimerization interface [polypeptide binding]; other site
209261003896	ligand binding site [chemical binding]; other site
209261003897	superoxide dismutase; Provisional; Region: PRK10543
209261003898	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
209261003899	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
209261003900	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
209261003901	NlpC/P60 family; Region: NLPC_P60; pfam00877
209261003902	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
209261003903	putative GSH binding site [chemical binding]; other site
209261003904	catalytic residues [active]
209261003905	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
209261003906	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
209261003907	dimer interface [polypeptide binding]; other site
209261003908	catalytic site [active]
209261003909	putative active site [active]
209261003910	putative substrate binding site [chemical binding]; other site
209261003911	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
209261003912	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
209261003913	dimer interface [polypeptide binding]; other site
209261003914	active site
209261003915	metal binding site [ion binding]; metal-binding site
209261003916	glutathione binding site [chemical binding]; other site
209261003917	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
209261003918	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
209261003919	FMN binding site [chemical binding]; other site
209261003920	active site
209261003921	substrate binding site [chemical binding]; other site
209261003922	catalytic residue [active]
209261003923	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
209261003924	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261003925	Predicted Fe-S protein [General function prediction only]; Region: COG3313
209261003926	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
209261003927	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
209261003928	active site
209261003929	catalytic tetrad [active]
209261003930	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
209261003931	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
209261003932	E-class dimer interface [polypeptide binding]; other site
209261003933	P-class dimer interface [polypeptide binding]; other site
209261003934	active site
209261003935	Cu2+ binding site [ion binding]; other site
209261003936	Zn2+ binding site [ion binding]; other site
209261003937	Fusaric acid resistance protein family; Region: FUSC; pfam04632
209261003938	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
209261003939	RNA polymerase Rpb4; Region: RNA_pol_Rpb4; cl00638
209261003940	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
209261003941	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
209261003942	HlyD family secretion protein; Region: HlyD_3; pfam13437
209261003943	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
209261003944	transcriptional regulator SlyA; Provisional; Region: PRK03573
209261003945	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
209261003946	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
209261003947	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
209261003948	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
209261003949	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
209261003950	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
209261003951	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
209261003952	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
209261003953	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
209261003954	active site
209261003955	HIGH motif; other site
209261003956	dimer interface [polypeptide binding]; other site
209261003957	KMSKS motif; other site
209261003958	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
209261003959	RNA binding surface [nucleotide binding]; other site
209261003960	pyridoxamine kinase; Validated; Region: PRK05756
209261003961	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
209261003962	dimer interface [polypeptide binding]; other site
209261003963	pyridoxal binding site [chemical binding]; other site
209261003964	ATP binding site [chemical binding]; other site
209261003965	glutathionine S-transferase; Provisional; Region: PRK10542
209261003966	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
209261003967	C-terminal domain interface [polypeptide binding]; other site
209261003968	GSH binding site (G-site) [chemical binding]; other site
209261003969	dimer interface [polypeptide binding]; other site
209261003970	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
209261003971	dimer interface [polypeptide binding]; other site
209261003972	N-terminal domain interface [polypeptide binding]; other site
209261003973	substrate binding pocket (H-site) [chemical binding]; other site
209261003974	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
209261003975	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261003976	putative substrate translocation pore; other site
209261003977	POT family; Region: PTR2; pfam00854
209261003978	endonuclease III; Provisional; Region: PRK10702
209261003979	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
209261003980	minor groove reading motif; other site
209261003981	helix-hairpin-helix signature motif; other site
209261003982	substrate binding pocket [chemical binding]; other site
209261003983	active site
209261003984	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
209261003985	electron transport complex RsxE subunit; Provisional; Region: PRK12405
209261003986	electron transport complex protein RnfG; Validated; Region: PRK01908
209261003987	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
209261003988	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
209261003989	SLBB domain; Region: SLBB; pfam10531
209261003990	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
209261003991	electron transport complex protein RnfB; Provisional; Region: PRK05113
209261003992	Putative Fe-S cluster; Region: FeS; cl17515
209261003993	4Fe-4S binding domain; Region: Fer4; pfam00037
209261003994	electron transport complex protein RsxA; Provisional; Region: PRK05151
209261003995	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
209261003996	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
209261003997	putative oxidoreductase; Provisional; Region: PRK11579
209261003998	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
209261003999	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
209261004000	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
209261004001	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
209261004002	active site
209261004003	purine riboside binding site [chemical binding]; other site
209261004004	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
209261004005	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
209261004006	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
209261004007	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
209261004008	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
209261004009	fumarate hydratase; Provisional; Region: PRK15389
209261004010	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
209261004011	Fumarase C-terminus; Region: Fumerase_C; pfam05683
209261004012	fumarate hydratase; Reviewed; Region: fumC; PRK00485
209261004013	Class II fumarases; Region: Fumarase_classII; cd01362
209261004014	active site
209261004015	tetramer interface [polypeptide binding]; other site
209261004016	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
209261004017	sensor protein RstB; Provisional; Region: PRK10604
209261004018	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261004019	dimerization interface [polypeptide binding]; other site
209261004020	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261004021	dimer interface [polypeptide binding]; other site
209261004022	phosphorylation site [posttranslational modification]
209261004023	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261004024	ATP binding site [chemical binding]; other site
209261004025	Mg2+ binding site [ion binding]; other site
209261004026	G-X-G motif; other site
209261004027	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
209261004028	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
209261004029	active site
209261004030	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
209261004031	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
209261004032	trimer interface [polypeptide binding]; other site
209261004033	eyelet of channel; other site
209261004034	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
209261004035	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261004036	active site
209261004037	phosphorylation site [posttranslational modification]
209261004038	intermolecular recognition site; other site
209261004039	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261004040	DNA binding site [nucleotide binding]
209261004041	GlpM protein; Region: GlpM; pfam06942
209261004042	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
209261004043	Spore germination protein; Region: Spore_permease; cl17796
209261004044	multiple promoter invertase; Provisional; Region: mpi; PRK13413
209261004045	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
209261004046	catalytic residues [active]
209261004047	catalytic nucleophile [active]
209261004048	Presynaptic Site I dimer interface [polypeptide binding]; other site
209261004049	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
209261004050	Synaptic Flat tetramer interface [polypeptide binding]; other site
209261004051	Synaptic Site I dimer interface [polypeptide binding]; other site
209261004052	DNA binding site [nucleotide binding]
209261004053	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
209261004054	DNA-binding interface [nucleotide binding]; DNA binding site
209261004055	alternative bacteriophage tail fiber C-terminus; corresponds to STY1642 from Accession AL513382: Salmonella typhi CT18
209261004056	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
209261004057	alternative bacteriophage tail fiber C-terminus; corresponds to STY1638 from Accession AL513382: Salmonella typhi CT18
209261004058	Phage Tail Collar Domain; Region: Collar; pfam07484
209261004059	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
209261004060	alternative bacteriophage tail fiber C-terminus; corresponds to STY1640 from Accession AL513382: Salmonella typhi CT18
209261004061	Phage Tail Collar Domain; Region: Collar; pfam07484
209261004062	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684
209261004063	Baseplate J-like protein; Region: Baseplate_J; cl01294
209261004064	Phage baseplate assembly protein W [General function prediction only]; Region: COG3628
209261004065	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
209261004066	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
209261004067	Phage protein D [General function prediction only]; Region: COG3500
209261004068	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
209261004069	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
209261004070	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
209261004071	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
209261004072	phage contractile tail tube protein, P2 family; Region: tail_tube; TIGR01611
209261004073	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
209261004074	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
209261004075	Gp37 protein; Region: Gp37; pfam09646
209261004076	Protein of unknown function (DUF1320); Region: DUF1320; pfam07030
209261004077	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
209261004078	Phage Mu protein F like protein; Region: Phage_Mu_F; pfam04233
209261004079	Protein of unknown function (DUF935); Region: DUF935; pfam06074
209261004080	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
209261004081	Terminase-like family; Region: Terminase_6; pfam03237
209261004082	Protein of unknown function (DUF3486); Region: DUF3486; pfam11985
209261004083	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK06476
209261004084	acetolactate synthase 3 catalytic subunit; Reviewed; Region: PRK06048
209261004085	phage lambda Rz-like lysis protein; Region: PHA00276
209261004086	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
209261004087	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
209261004088	N-acetyl-D-glucosamine binding site [chemical binding]; other site
209261004089	catalytic residue [active]
209261004090	Protein of unknown function (DUF4063); Region: DUF4063; pfam13272
209261004091	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
209261004092	Integrase core domain; Region: rve; pfam00665
209261004093	Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]; Region: ExeA; COG3267
209261004094	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261004095	Walker A/P-loop; other site
209261004096	ATP binding site [chemical binding]; other site
209261004097	Bacteriophage Mu Gam like protein; Region: Phage_Mu_Gam; cl01825
209261004098	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u2; cd11539
209261004099	metal binding site [ion binding]; metal-binding site
209261004100	Protein of unknown function (DUF1018); Region: DUF1018; pfam06252
209261004101	Mor transcription activator family; Region: Mor; pfam08765
209261004102	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
209261004103	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
209261004104	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
209261004105	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
209261004106	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
209261004107	ligand binding site [chemical binding]; other site
209261004108	homodimer interface [polypeptide binding]; other site
209261004109	NAD(P) binding site [chemical binding]; other site
209261004110	trimer interface B [polypeptide binding]; other site
209261004111	trimer interface A [polypeptide binding]; other site
209261004112	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
209261004113	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
209261004114	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
209261004115	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
209261004116	Domain of unknown function DUF20; Region: UPF0118; pfam01594
209261004117	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
209261004118	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
209261004119	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
209261004120	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261004121	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
209261004122	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261004123	putative substrate translocation pore; other site
209261004124	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
209261004125	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261004126	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
209261004127	dimerization interface [polypeptide binding]; other site
209261004128	substrate binding pocket [chemical binding]; other site
209261004129	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
209261004130	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
209261004131	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
209261004132	nucleotide binding site [chemical binding]; other site
209261004133	putative dithiobiotin synthetase; Provisional; Region: PRK12374
209261004134	AAA domain; Region: AAA_26; pfam13500
209261004135	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
209261004136	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
209261004137	Cl- selectivity filter; other site
209261004138	Cl- binding residues [ion binding]; other site
209261004139	pore gating glutamate residue; other site
209261004140	dimer interface [polypeptide binding]; other site
209261004141	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
209261004142	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
209261004143	Walker A/P-loop; other site
209261004144	ATP binding site [chemical binding]; other site
209261004145	Q-loop/lid; other site
209261004146	ABC transporter signature motif; other site
209261004147	Walker B; other site
209261004148	D-loop; other site
209261004149	H-loop/switch region; other site
209261004150	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
209261004151	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261004152	dimer interface [polypeptide binding]; other site
209261004153	conserved gate region; other site
209261004154	ABC-ATPase subunit interface; other site
209261004155	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
209261004156	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261004157	dimer interface [polypeptide binding]; other site
209261004158	conserved gate region; other site
209261004159	putative PBP binding loops; other site
209261004160	ABC-ATPase subunit interface; other site
209261004161	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
209261004162	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
209261004163	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
209261004164	4Fe-4S binding domain; Region: Fer4; pfam00037
209261004165	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
209261004166	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
209261004167	putative [Fe4-S4] binding site [ion binding]; other site
209261004168	putative molybdopterin cofactor binding site [chemical binding]; other site
209261004169	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
209261004170	putative molybdopterin cofactor binding site; other site
209261004171	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
209261004172	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
209261004173	putative [Fe4-S4] binding site [ion binding]; other site
209261004174	putative molybdopterin cofactor binding site [chemical binding]; other site
209261004175	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
209261004176	putative molybdopterin cofactor binding site; other site
209261004177	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
209261004178	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
209261004179	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261004180	Coenzyme A binding pocket [chemical binding]; other site
209261004181	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
209261004182	hypothetical protein; Provisional; Region: PRK13659
209261004183	hypothetical protein; Provisional; Region: PRK02237
209261004184	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
209261004185	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
209261004186	putative active site pocket [active]
209261004187	putative metal binding site [ion binding]; other site
209261004188	putative oxidoreductase; Provisional; Region: PRK10083
209261004189	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
209261004190	putative NAD(P) binding site [chemical binding]; other site
209261004191	catalytic Zn binding site [ion binding]; other site
209261004192	structural Zn binding site [ion binding]; other site
209261004193	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261004194	metabolite-proton symporter; Region: 2A0106; TIGR00883
209261004195	putative substrate translocation pore; other site
209261004196	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
209261004197	Transcriptional regulators [Transcription]; Region: GntR; COG1802
209261004198	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261004199	DNA-binding site [nucleotide binding]; DNA binding site
209261004200	FCD domain; Region: FCD; pfam07729
209261004201	malonic semialdehyde reductase; Provisional; Region: PRK10538
209261004202	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
209261004203	putative NAD(P) binding site [chemical binding]; other site
209261004204	homodimer interface [polypeptide binding]; other site
209261004205	homotetramer interface [polypeptide binding]; other site
209261004206	active site
209261004207	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
209261004208	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
209261004209	active site
209261004210	Zn binding site [ion binding]; other site
209261004211	General stress protein [General function prediction only]; Region: GsiB; COG3729
209261004212	hypothetical protein; Validated; Region: PRK03657
209261004213	hypothetical protein; Provisional; Region: PRK10053
209261004214	putative transporter; Provisional; Region: PRK10054
209261004215	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261004216	putative substrate translocation pore; other site
209261004217	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
209261004218	EamA-like transporter family; Region: EamA; pfam00892
209261004219	MarB protein; Region: MarB; pfam13999
209261004220	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
209261004221	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261004222	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261004223	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
209261004224	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
209261004225	inner membrane protein; Provisional; Region: PRK10995
209261004226	putative arabinose transporter; Provisional; Region: PRK03545
209261004227	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261004228	putative substrate translocation pore; other site
209261004229	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261004230	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261004231	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
209261004232	putative dimerization interface [polypeptide binding]; other site
209261004233	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
209261004234	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
209261004235	NAD(P) binding site [chemical binding]; other site
209261004236	catalytic residues [active]
209261004237	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
209261004238	glutaminase; Provisional; Region: PRK00971
209261004239	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
209261004240	Predicted membrane protein [Function unknown]; Region: COG3781
209261004241	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
209261004242	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
209261004243	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
209261004244	Rubredoxin [Energy production and conversion]; Region: COG1773
209261004245	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
209261004246	iron binding site [ion binding]; other site
209261004247	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
209261004248	HupF/HypC family; Region: HupF_HypC; cl00394
209261004249	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
209261004250	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
209261004251	putative substrate-binding site; other site
209261004252	nickel binding site [ion binding]; other site
209261004253	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
209261004254	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
209261004255	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
209261004256	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
209261004257	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
209261004258	active site
209261004259	Transcriptional regulators [Transcription]; Region: FadR; COG2186
209261004260	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261004261	DNA-binding site [nucleotide binding]; DNA binding site
209261004262	FCD domain; Region: FCD; pfam07729
209261004263	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
209261004264	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
209261004265	putative NAD(P) binding site [chemical binding]; other site
209261004266	catalytic Zn binding site [ion binding]; other site
209261004267	structural Zn binding site [ion binding]; other site
209261004268	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261004269	D-galactonate transporter; Region: 2A0114; TIGR00893
209261004270	putative substrate translocation pore; other site
209261004271	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
209261004272	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261004273	Major Facilitator Superfamily; Region: MFS_1; pfam07690
209261004274	putative substrate translocation pore; other site
209261004275	Transcriptional regulators [Transcription]; Region: MarR; COG1846
209261004276	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
209261004277	putative DNA binding site [nucleotide binding]; other site
209261004278	putative Zn2+ binding site [ion binding]; other site
209261004279	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
209261004280	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
209261004281	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
209261004282	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
209261004283	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261004284	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261004285	homodimer interface [polypeptide binding]; other site
209261004286	catalytic residue [active]
209261004287	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
209261004288	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
209261004289	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
209261004290	active site
209261004291	catalytic site [active]
209261004292	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
209261004293	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
209261004294	active site
209261004295	catalytic site [active]
209261004296	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
209261004297	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
209261004298	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
209261004299	catalytic site [active]
209261004300	active site
209261004301	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
209261004302	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
209261004303	acid-resistance protein; Provisional; Region: hdeB; PRK11566
209261004304	hemolysin E; Provisional; Region: hlyE; PRK11376
209261004305	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
209261004306	biofilm-dependent modulation protein; Provisional; Region: PRK11436
209261004307	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
209261004308	malate dehydrogenase; Provisional; Region: PRK13529
209261004309	Malic enzyme, N-terminal domain; Region: malic; pfam00390
209261004310	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
209261004311	NAD(P) binding site [chemical binding]; other site
209261004312	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
209261004313	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
209261004314	NAD binding site [chemical binding]; other site
209261004315	substrate binding site [chemical binding]; other site
209261004316	catalytic Zn binding site [ion binding]; other site
209261004317	tetramer interface [polypeptide binding]; other site
209261004318	structural Zn binding site [ion binding]; other site
209261004319	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
209261004320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261004321	putative substrate translocation pore; other site
209261004322	TetR family transcriptional regulator; Provisional; Region: PRK14996
209261004323	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261004324	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
209261004325	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
209261004326	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
209261004327	[4Fe-4S] binding site [ion binding]; other site
209261004328	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
209261004329	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
209261004330	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
209261004331	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
209261004332	molybdopterin cofactor binding site; other site
209261004333	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
209261004334	hypothetical protein; Provisional; Region: PRK10281
209261004335	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
209261004336	L-asparagine permease; Provisional; Region: PRK15049
209261004337	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
209261004338	Uncharacterized conserved protein [Function unknown]; Region: COG3391
209261004339	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
209261004340	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
209261004341	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
209261004342	N-terminal plug; other site
209261004343	ligand-binding site [chemical binding]; other site
209261004344	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
209261004345	DNA-binding site [nucleotide binding]; DNA binding site
209261004346	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
209261004347	FCD domain; Region: FCD; pfam07729
209261004348	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
209261004349	Prostaglandin dehydrogenases; Region: PGDH; cd05288
209261004350	NAD(P) binding site [chemical binding]; other site
209261004351	substrate binding site [chemical binding]; other site
209261004352	dimer interface [polypeptide binding]; other site
209261004353	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
209261004354	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
209261004355	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
209261004356	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
209261004357	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
209261004358	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
209261004359	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
209261004360	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
209261004361	tetrameric interface [polypeptide binding]; other site
209261004362	NAD binding site [chemical binding]; other site
209261004363	catalytic residues [active]
209261004364	substrate binding site [chemical binding]; other site
209261004365	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
209261004366	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261004367	DNA-binding site [nucleotide binding]; DNA binding site
209261004368	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261004369	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261004370	homodimer interface [polypeptide binding]; other site
209261004371	catalytic residue [active]
209261004372	D-alanyl-D-alanine dipeptidase [Cell envelope biogenesis, outer membrane]; Region: DdpX; COG2173
209261004373	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
209261004374	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
209261004375	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
209261004376	Peptidase family U32; Region: Peptidase_U32; pfam01136
209261004377	Collagenase; Region: DUF3656; pfam12392
209261004378	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
209261004379	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261004380	non-specific DNA binding site [nucleotide binding]; other site
209261004381	salt bridge; other site
209261004382	sequence-specific DNA binding site [nucleotide binding]; other site
209261004383	Cupin domain; Region: Cupin_2; pfam07883
209261004384	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
209261004385	benzoate transporter; Region: benE; TIGR00843
209261004386	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
209261004387	tellurite resistance protein TehB; Provisional; Region: PRK11207
209261004388	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261004389	S-adenosylmethionine binding site [chemical binding]; other site
209261004390	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
209261004391	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
209261004392	gating phenylalanine in ion channel; other site
209261004393	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
209261004394	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
209261004395	putative trimer interface [polypeptide binding]; other site
209261004396	putative CoA binding site [chemical binding]; other site
209261004397	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
209261004398	putative trimer interface [polypeptide binding]; other site
209261004399	putative CoA binding site [chemical binding]; other site
209261004400	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
209261004401	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261004402	Coenzyme A binding pocket [chemical binding]; other site
209261004403	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
209261004404	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
209261004405	oligomer interface [polypeptide binding]; other site
209261004406	active site
209261004407	metal binding site [ion binding]; metal-binding site
209261004408	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
209261004409	active site
209261004410	P-loop; other site
209261004411	phosphorylation site [posttranslational modification]
209261004412	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
209261004413	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
209261004414	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
209261004415	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
209261004416	active site
209261004417	phosphorylation site [posttranslational modification]
209261004418	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
209261004419	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
209261004420	substrate binding site [chemical binding]; other site
209261004421	hexamer interface [polypeptide binding]; other site
209261004422	metal binding site [ion binding]; metal-binding site
209261004423	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
209261004424	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
209261004425	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261004426	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261004427	Coenzyme A binding pocket [chemical binding]; other site
209261004428	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
209261004429	teramer interface [polypeptide binding]; other site
209261004430	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
209261004431	active site
209261004432	FMN binding site [chemical binding]; other site
209261004433	catalytic residues [active]
209261004434	Uncharacterized conserved protein [Function unknown]; Region: COG2353
209261004435	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
209261004436	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
209261004437	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
209261004438	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
209261004439	substrate binding pocket [chemical binding]; other site
209261004440	catalytic triad [active]
209261004441	Predicted membrane protein [Function unknown]; Region: COG3326
209261004442	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261004443	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
209261004444	substrate binding pocket [chemical binding]; other site
209261004445	membrane-bound complex binding site; other site
209261004446	hinge residues; other site
209261004447	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
209261004448	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261004449	dimer interface [polypeptide binding]; other site
209261004450	conserved gate region; other site
209261004451	putative PBP binding loops; other site
209261004452	ABC-ATPase subunit interface; other site
209261004453	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
209261004454	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261004455	Walker A/P-loop; other site
209261004456	ATP binding site [chemical binding]; other site
209261004457	Q-loop/lid; other site
209261004458	ABC transporter signature motif; other site
209261004459	Walker B; other site
209261004460	D-loop; other site
209261004461	H-loop/switch region; other site
209261004462	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
209261004463	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261004464	dimer interface [polypeptide binding]; other site
209261004465	conserved gate region; other site
209261004466	putative PBP binding loops; other site
209261004467	ABC-ATPase subunit interface; other site
209261004468	Predicted membrane protein [Function unknown]; Region: COG5305
209261004469	Methyltransferase domain; Region: Methyltransf_12; pfam08242
209261004470	cytochrome b561; Provisional; Region: PRK11513
209261004471	Uncharacterized conserved protein [Function unknown]; Region: COG1434
209261004472	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
209261004473	putative active site [active]
209261004474	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
209261004475	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261004476	ATP binding site [chemical binding]; other site
209261004477	putative Mg++ binding site [ion binding]; other site
209261004478	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261004479	nucleotide binding region [chemical binding]; other site
209261004480	ATP-binding site [chemical binding]; other site
209261004481	Helicase associated domain (HA2); Region: HA2; pfam04408
209261004482	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
209261004483	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
209261004484	azoreductase; Reviewed; Region: PRK00170
209261004485	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
209261004486	Uncharacterized conserved protein [Function unknown]; Region: COG3791
209261004487	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
209261004488	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
209261004489	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
209261004490	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
209261004491	putative ligand binding site [chemical binding]; other site
209261004492	putative NAD binding site [chemical binding]; other site
209261004493	catalytic site [active]
209261004494	heat-inducible protein; Provisional; Region: PRK10449
209261004495	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
209261004496	Domain of unknown function (DUF333); Region: DUF333; pfam03891
209261004497	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
209261004498	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
209261004499	dimer interface [polypeptide binding]; other site
209261004500	PYR/PP interface [polypeptide binding]; other site
209261004501	TPP binding site [chemical binding]; other site
209261004502	substrate binding site [chemical binding]; other site
209261004503	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
209261004504	Domain of unknown function; Region: EKR; smart00890
209261004505	4Fe-4S binding domain; Region: Fer4_6; pfam12837
209261004506	4Fe-4S binding domain; Region: Fer4; pfam00037
209261004507	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
209261004508	TPP-binding site [chemical binding]; other site
209261004509	dimer interface [polypeptide binding]; other site
209261004510	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261004511	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
209261004512	Ligand Binding Site [chemical binding]; other site
209261004513	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
209261004514	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
209261004515	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
209261004516	Ligand Binding Site [chemical binding]; other site
209261004517	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
209261004518	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
209261004519	Cl binding site [ion binding]; other site
209261004520	oligomer interface [polypeptide binding]; other site
209261004521	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
209261004522	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
209261004523	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
209261004524	dimer interface [polypeptide binding]; other site
209261004525	putative CheW interface [polypeptide binding]; other site
209261004526	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
209261004527	Smr domain; Region: Smr; pfam01713
209261004528	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
209261004529	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
209261004530	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
209261004531	DNA binding site [nucleotide binding]
209261004532	active site
209261004533	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
209261004534	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
209261004535	ligand binding site [chemical binding]; other site
209261004536	flexible hinge region; other site
209261004537	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
209261004538	putative switch regulator; other site
209261004539	non-specific DNA interactions [nucleotide binding]; other site
209261004540	DNA binding site [nucleotide binding]
209261004541	sequence specific DNA binding site [nucleotide binding]; other site
209261004542	putative cAMP binding site [chemical binding]; other site
209261004543	universal stress protein UspE; Provisional; Region: PRK11175
209261004544	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
209261004545	Ligand Binding Site [chemical binding]; other site
209261004546	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
209261004547	Ligand Binding Site [chemical binding]; other site
209261004548	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
209261004549	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
209261004550	Mechanosensitive ion channel; Region: MS_channel; pfam00924
209261004551	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
209261004552	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261004553	non-specific DNA binding site [nucleotide binding]; other site
209261004554	salt bridge; other site
209261004555	sequence-specific DNA binding site [nucleotide binding]; other site
209261004556	Cupin domain; Region: Cupin_2; pfam07883
209261004557	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
209261004558	B3/4 domain; Region: B3_4; pfam03483
209261004559	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: Tpx; COG2077
209261004560	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
209261004561	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
209261004562	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261004563	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
209261004564	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
209261004565	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
209261004566	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261004567	oxidoreductase; Provisional; Region: PRK12742
209261004568	classical (c) SDRs; Region: SDR_c; cd05233
209261004569	NAD(P) binding site [chemical binding]; other site
209261004570	active site
209261004571	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
209261004572	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
209261004573	active site
209261004574	catalytic tetrad [active]
209261004575	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261004576	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261004577	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
209261004578	putative effector binding pocket; other site
209261004579	putative dimerization interface [polypeptide binding]; other site
209261004580	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
209261004581	NmrA-like family; Region: NmrA; pfam05368
209261004582	NAD(P) binding site [chemical binding]; other site
209261004583	active site lysine
209261004584	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
209261004585	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
209261004586	peptide binding site [polypeptide binding]; other site
209261004587	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
209261004588	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
209261004589	putative active site [active]
209261004590	Zn binding site [ion binding]; other site
209261004591	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
209261004592	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
209261004593	active site
209261004594	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
209261004595	dimer interface [polypeptide binding]; other site
209261004596	catalytic triad [active]
209261004597	peroxidatic and resolving cysteines [active]
209261004598	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261004599	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
209261004600	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
209261004601	putative aromatic amino acid binding site; other site
209261004602	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261004603	Walker A motif; other site
209261004604	ATP binding site [chemical binding]; other site
209261004605	Walker B motif; other site
209261004606	arginine finger; other site
209261004607	hypothetical protein; Provisional; Region: PRK05415
209261004608	TIGR01620 family protein; Region: hyp_HI0043
209261004609	Predicted ATPase [General function prediction only]; Region: COG3106
209261004610	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
209261004611	active site residue [active]
209261004612	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
209261004613	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
209261004614	phage shock protein C; Region: phageshock_pspC; TIGR02978
209261004615	phage shock protein B; Provisional; Region: pspB; PRK09458
209261004616	phage shock protein PspA; Provisional; Region: PRK10698
209261004617	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
209261004618	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261004619	Walker A motif; other site
209261004620	ATP binding site [chemical binding]; other site
209261004621	Walker B motif; other site
209261004622	arginine finger; other site
209261004623	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
209261004624	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
209261004625	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
209261004626	peptide binding site [polypeptide binding]; other site
209261004627	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
209261004628	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261004629	dimer interface [polypeptide binding]; other site
209261004630	conserved gate region; other site
209261004631	putative PBP binding loops; other site
209261004632	ABC-ATPase subunit interface; other site
209261004633	subtilase cytotoxin subunit B-like protein; Provisional; Region: PRK15267
209261004634	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
209261004635	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
209261004636	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261004637	dimer interface [polypeptide binding]; other site
209261004638	conserved gate region; other site
209261004639	putative PBP binding loops; other site
209261004640	ABC-ATPase subunit interface; other site
209261004641	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
209261004642	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261004643	Walker A/P-loop; other site
209261004644	ATP binding site [chemical binding]; other site
209261004645	Q-loop/lid; other site
209261004646	ABC transporter signature motif; other site
209261004647	Walker B; other site
209261004648	D-loop; other site
209261004649	H-loop/switch region; other site
209261004650	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
209261004651	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
209261004652	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261004653	Walker A/P-loop; other site
209261004654	ATP binding site [chemical binding]; other site
209261004655	Q-loop/lid; other site
209261004656	ABC transporter signature motif; other site
209261004657	Walker B; other site
209261004658	D-loop; other site
209261004659	H-loop/switch region; other site
209261004660	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
209261004661	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
209261004662	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
209261004663	NAD binding site [chemical binding]; other site
209261004664	homotetramer interface [polypeptide binding]; other site
209261004665	homodimer interface [polypeptide binding]; other site
209261004666	substrate binding site [chemical binding]; other site
209261004667	active site
209261004668	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
209261004669	exoribonuclease II; Provisional; Region: PRK05054
209261004670	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
209261004671	RNB domain; Region: RNB; pfam00773
209261004672	S1 RNA binding domain; Region: S1; pfam00575
209261004673	RNase II stability modulator; Provisional; Region: PRK10060
209261004674	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
209261004675	putative active site [active]
209261004676	heme pocket [chemical binding]; other site
209261004677	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
209261004678	metal binding site [ion binding]; metal-binding site
209261004679	active site
209261004680	I-site; other site
209261004681	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261004682	hypothetical protein; Provisional; Region: PRK13658
209261004683	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
209261004684	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
209261004685	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261004686	lipoprotein; Provisional; Region: PRK10540
209261004687	translation initiation factor Sui1; Validated; Region: PRK06824
209261004688	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
209261004689	putative rRNA binding site [nucleotide binding]; other site
209261004690	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
209261004691	active site
209261004692	dimer interface [polypeptide binding]; other site
209261004693	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
209261004694	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
209261004695	binding surface
209261004696	TPR motif; other site
209261004697	Predicted membrane protein [Function unknown]; Region: COG3771
209261004698	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
209261004699	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
209261004700	active site
209261004701	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
209261004702	dimerization interface [polypeptide binding]; other site
209261004703	active site
209261004704	aconitate hydratase; Validated; Region: PRK09277
209261004705	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
209261004706	substrate binding site [chemical binding]; other site
209261004707	ligand binding site [chemical binding]; other site
209261004708	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
209261004709	substrate binding site [chemical binding]; other site
209261004710	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
209261004711	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261004712	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
209261004713	substrate binding site [chemical binding]; other site
209261004714	putative dimerization interface [polypeptide binding]; other site
209261004715	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
209261004716	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
209261004717	active site
209261004718	interdomain interaction site; other site
209261004719	putative metal-binding site [ion binding]; other site
209261004720	nucleotide binding site [chemical binding]; other site
209261004721	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
209261004722	domain I; other site
209261004723	DNA binding groove [nucleotide binding]
209261004724	phosphate binding site [ion binding]; other site
209261004725	domain II; other site
209261004726	domain III; other site
209261004727	nucleotide binding site [chemical binding]; other site
209261004728	catalytic site [active]
209261004729	domain IV; other site
209261004730	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
209261004731	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
209261004732	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
209261004733	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
209261004734	hypothetical protein; Provisional; Region: PRK11037
209261004735	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
209261004736	putative inner membrane peptidase; Provisional; Region: PRK11778
209261004737	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
209261004738	tandem repeat interface [polypeptide binding]; other site
209261004739	oligomer interface [polypeptide binding]; other site
209261004740	active site residues [active]
209261004741	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
209261004742	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
209261004743	NADP binding site [chemical binding]; other site
209261004744	homodimer interface [polypeptide binding]; other site
209261004745	active site
209261004746	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
209261004747	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
209261004748	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
209261004749	homodimer interface [polypeptide binding]; other site
209261004750	Walker A motif; other site
209261004751	ATP binding site [chemical binding]; other site
209261004752	hydroxycobalamin binding site [chemical binding]; other site
209261004753	Walker B motif; other site
209261004754	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
209261004755	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
209261004756	RNA binding surface [nucleotide binding]; other site
209261004757	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
209261004758	probable active site [active]
209261004759	hypothetical protein; Provisional; Region: PRK11630
209261004760	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
209261004761	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
209261004762	active site
209261004763	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
209261004764	anthranilate synthase component I; Provisional; Region: PRK13564
209261004765	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
209261004766	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
209261004767	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
209261004768	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
209261004769	glutamine binding [chemical binding]; other site
209261004770	catalytic triad [active]
209261004771	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
209261004772	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
209261004773	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
209261004774	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
209261004775	active site
209261004776	ribulose/triose binding site [chemical binding]; other site
209261004777	phosphate binding site [ion binding]; other site
209261004778	substrate (anthranilate) binding pocket [chemical binding]; other site
209261004779	product (indole) binding pocket [chemical binding]; other site
209261004780	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
209261004781	active site
209261004782	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
209261004783	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
209261004784	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261004785	catalytic residue [active]
209261004786	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
209261004787	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
209261004788	substrate binding site [chemical binding]; other site
209261004789	active site
209261004790	catalytic residues [active]
209261004791	heterodimer interface [polypeptide binding]; other site
209261004792	General stress protein [General function prediction only]; Region: GsiB; COG3729
209261004793	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
209261004794	dimerization interface [polypeptide binding]; other site
209261004795	metal binding site [ion binding]; metal-binding site
209261004796	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
209261004797	dinuclear metal binding motif [ion binding]; other site
209261004798	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
209261004799	dimanganese center [ion binding]; other site
209261004800	outer membrane protein W; Provisional; Region: PRK10959
209261004801	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
209261004802	hypothetical protein; Provisional; Region: PRK02868
209261004803	intracellular septation protein A; Reviewed; Region: PRK00259
209261004804	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
209261004805	transport protein TonB; Provisional; Region: PRK10819
209261004806	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
209261004807	YciI-like protein; Reviewed; Region: PRK11370
209261004808	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
209261004809	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
209261004810	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
209261004811	putative active site [active]
209261004812	catalytic site [active]
209261004813	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
209261004814	putative active site [active]
209261004815	catalytic site [active]
209261004816	dsDNA-mimic protein; Reviewed; Region: PRK05094
209261004817	Ion transport protein; Region: Ion_trans; pfam00520
209261004818	Ion channel; Region: Ion_trans_2; pfam07885
209261004819	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
209261004820	Double zinc ribbon; Region: DZR; pfam12773
209261004821	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
209261004822	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261004823	Walker A/P-loop; other site
209261004824	ATP binding site [chemical binding]; other site
209261004825	Q-loop/lid; other site
209261004826	ABC transporter signature motif; other site
209261004827	Walker B; other site
209261004828	D-loop; other site
209261004829	H-loop/switch region; other site
209261004830	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
209261004831	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
209261004832	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261004833	Walker A/P-loop; other site
209261004834	ATP binding site [chemical binding]; other site
209261004835	Q-loop/lid; other site
209261004836	ABC transporter signature motif; other site
209261004837	Walker B; other site
209261004838	D-loop; other site
209261004839	H-loop/switch region; other site
209261004840	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
209261004841	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
209261004842	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261004843	dimer interface [polypeptide binding]; other site
209261004844	conserved gate region; other site
209261004845	putative PBP binding loops; other site
209261004846	ABC-ATPase subunit interface; other site
209261004847	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
209261004848	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
209261004849	peptide binding site [polypeptide binding]; other site
209261004850	hypothetical protein; Provisional; Region: PRK11111
209261004851	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
209261004852	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
209261004853	putative catalytic cysteine [active]
209261004854	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
209261004855	putative active site [active]
209261004856	metal binding site [ion binding]; metal-binding site
209261004857	thymidine kinase; Provisional; Region: PRK04296
209261004858	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
209261004859	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
209261004860	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
209261004861	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
209261004862	active site
209261004863	tetramer interface; other site
209261004864	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261004865	active site
209261004866	response regulator of RpoS; Provisional; Region: PRK10693
209261004867	phosphorylation site [posttranslational modification]
209261004868	intermolecular recognition site; other site
209261004869	dimerization interface [polypeptide binding]; other site
209261004870	hypothetical protein; Provisional; Region: PRK10279
209261004871	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
209261004872	active site
209261004873	nucleophile elbow; other site
209261004874	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
209261004875	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
209261004876	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
209261004877	putative active site [active]
209261004878	putative substrate binding site [chemical binding]; other site
209261004879	putative cosubstrate binding site; other site
209261004880	catalytic site [active]
209261004881	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
209261004882	Sel1-like repeats; Region: SEL1; smart00671
209261004883	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
209261004884	Sel1-like repeats; Region: SEL1; smart00671
209261004885	Sel1-like repeats; Region: SEL1; smart00671
209261004886	Sel1-like repeats; Region: SEL1; smart00671
209261004887	Sel1-like repeats; Region: SEL1; smart00671
209261004888	Sel1-like repeats; Region: SEL1; smart00671
209261004889	Sel1-like repeats; Region: SEL1; smart00671
209261004890	Sel1-like repeats; Region: SEL1; smart00671
209261004891	Sel1-like repeats; Region: SEL1; smart00671
209261004892	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
209261004893	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
209261004894	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
209261004895	4Fe-4S binding domain; Region: Fer4; cl02805
209261004896	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
209261004897	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
209261004898	[4Fe-4S] binding site [ion binding]; other site
209261004899	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
209261004900	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
209261004901	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
209261004902	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
209261004903	molybdopterin cofactor binding site; other site
209261004904	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
209261004905	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
209261004906	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
209261004907	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261004908	dimerization interface [polypeptide binding]; other site
209261004909	Histidine kinase; Region: HisKA_3; pfam07730
209261004910	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261004911	ATP binding site [chemical binding]; other site
209261004912	Mg2+ binding site [ion binding]; other site
209261004913	G-X-G motif; other site
209261004914	transcriptional regulator NarL; Provisional; Region: PRK10651
209261004915	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261004916	active site
209261004917	phosphorylation site [posttranslational modification]
209261004918	intermolecular recognition site; other site
209261004919	dimerization interface [polypeptide binding]; other site
209261004920	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261004921	DNA binding residues [nucleotide binding]
209261004922	dimerization interface [polypeptide binding]; other site
209261004923	putative invasin; Provisional; Region: PRK10177
209261004924	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
209261004925	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
209261004926	cation transport regulator; Reviewed; Region: chaB; PRK09582
209261004927	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
209261004928	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
209261004929	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261004930	isocitrate dehydrogenase; Validated; Region: PRK07362
209261004931	isocitrate dehydrogenase; Reviewed; Region: PRK07006
209261004932	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
209261004933	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
209261004934	probable active site [active]
209261004935	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
209261004936	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
209261004937	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
209261004938	nudix motif; other site
209261004939	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
209261004940	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
209261004941	putative lysogenization regulator; Reviewed; Region: PRK00218
209261004942	adenylosuccinate lyase; Provisional; Region: PRK09285
209261004943	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
209261004944	tetramer interface [polypeptide binding]; other site
209261004945	active site
209261004946	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
209261004947	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261004948	active site
209261004949	phosphorylation site [posttranslational modification]
209261004950	intermolecular recognition site; other site
209261004951	dimerization interface [polypeptide binding]; other site
209261004952	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261004953	DNA binding site [nucleotide binding]
209261004954	sensor protein PhoQ; Provisional; Region: PRK10815
209261004955	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
209261004956	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
209261004957	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261004958	ATP binding site [chemical binding]; other site
209261004959	Mg2+ binding site [ion binding]; other site
209261004960	G-X-G motif; other site
209261004961	Uncharacterized conserved protein [Function unknown]; Region: COG2850
209261004962	Cupin domain; Region: Cupin_2; cl17218
209261004963	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
209261004964	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
209261004965	metal binding site [ion binding]; metal-binding site
209261004966	dimer interface [polypeptide binding]; other site
209261004967	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
209261004968	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261004969	Walker A/P-loop; other site
209261004970	ATP binding site [chemical binding]; other site
209261004971	Q-loop/lid; other site
209261004972	ABC transporter signature motif; other site
209261004973	Walker B; other site
209261004974	D-loop; other site
209261004975	H-loop/switch region; other site
209261004976	TOBE domain; Region: TOBE_2; pfam08402
209261004977	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
209261004978	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261004979	dimer interface [polypeptide binding]; other site
209261004980	conserved gate region; other site
209261004981	putative PBP binding loops; other site
209261004982	ABC-ATPase subunit interface; other site
209261004983	secreted effector protein SifA; Reviewed; Region: sifA; PRK09498
209261004984	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
209261004985	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261004986	dimer interface [polypeptide binding]; other site
209261004987	conserved gate region; other site
209261004988	putative PBP binding loops; other site
209261004989	ABC-ATPase subunit interface; other site
209261004990	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
209261004991	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
209261004992	NAD-dependent deacetylase; Provisional; Region: PRK00481
209261004993	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
209261004994	NAD+ binding site [chemical binding]; other site
209261004995	substrate binding site [chemical binding]; other site
209261004996	Zn binding site [ion binding]; other site
209261004997	fructokinase; Reviewed; Region: PRK09557
209261004998	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
209261004999	nucleotide binding site [chemical binding]; other site
209261005000	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
209261005001	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
209261005002	FtsX-like permease family; Region: FtsX; pfam02687
209261005003	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
209261005004	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
209261005005	Walker A/P-loop; other site
209261005006	ATP binding site [chemical binding]; other site
209261005007	Q-loop/lid; other site
209261005008	ABC transporter signature motif; other site
209261005009	Walker B; other site
209261005010	D-loop; other site
209261005011	H-loop/switch region; other site
209261005012	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
209261005013	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
209261005014	FtsX-like permease family; Region: FtsX; pfam02687
209261005015	transcription-repair coupling factor; Provisional; Region: PRK10689
209261005016	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
209261005017	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261005018	ATP binding site [chemical binding]; other site
209261005019	putative Mg++ binding site [ion binding]; other site
209261005020	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261005021	nucleotide binding region [chemical binding]; other site
209261005022	ATP-binding site [chemical binding]; other site
209261005023	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
209261005024	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
209261005025	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
209261005026	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
209261005027	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
209261005028	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
209261005029	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261005030	hypothetical protein; Provisional; Region: PRK11280
209261005031	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
209261005032	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261005033	hypothetical protein; Provisional; Region: PRK04940
209261005034	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
209261005035	beta-hexosaminidase; Provisional; Region: PRK05337
209261005036	thiamine kinase; Region: ycfN_thiK; TIGR02721
209261005037	thiamine kinase; Provisional; Region: thiK; PRK10271
209261005038	substrate binding site [chemical binding]; other site
209261005039	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
209261005040	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
209261005041	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
209261005042	putative dimer interface [polypeptide binding]; other site
209261005043	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
209261005044	nucleotide binding site/active site [active]
209261005045	HIT family signature motif; other site
209261005046	catalytic residue [active]
209261005047	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
209261005048	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
209261005049	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
209261005050	active site turn [active]
209261005051	phosphorylation site [posttranslational modification]
209261005052	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
209261005053	active site
209261005054	DNA polymerase III subunit delta'; Validated; Region: PRK07993
209261005055	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
209261005056	thymidylate kinase; Validated; Region: tmk; PRK00698
209261005057	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
209261005058	TMP-binding site; other site
209261005059	ATP-binding site [chemical binding]; other site
209261005060	conserved hypothetical protein, YceG family; Region: TIGR00247
209261005061	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
209261005062	dimerization interface [polypeptide binding]; other site
209261005063	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
209261005064	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
209261005065	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261005066	catalytic residue [active]
209261005067	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
209261005068	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
209261005069	dimer interface [polypeptide binding]; other site
209261005070	active site
209261005071	acyl carrier protein; Provisional; Region: acpP; PRK00982
209261005072	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
209261005073	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
209261005074	NAD(P) binding site [chemical binding]; other site
209261005075	homotetramer interface [polypeptide binding]; other site
209261005076	homodimer interface [polypeptide binding]; other site
209261005077	active site
209261005078	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
209261005079	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
209261005080	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
209261005081	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
209261005082	dimer interface [polypeptide binding]; other site
209261005083	active site
209261005084	CoA binding pocket [chemical binding]; other site
209261005085	putative phosphate acyltransferase; Provisional; Region: PRK05331
209261005086	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
209261005087	hypothetical protein; Provisional; Region: PRK11193
209261005088	Maf-like protein; Region: Maf; pfam02545
209261005089	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
209261005090	active site
209261005091	dimer interface [polypeptide binding]; other site
209261005092	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
209261005093	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
209261005094	RNA binding surface [nucleotide binding]; other site
209261005095	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
209261005096	active site
209261005097	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
209261005098	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
209261005099	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
209261005100	homodimer interface [polypeptide binding]; other site
209261005101	oligonucleotide binding site [chemical binding]; other site
209261005102	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
209261005103	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261005104	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
209261005105	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
209261005106	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
209261005107	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
209261005108	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
209261005109	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
209261005110	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
209261005111	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
209261005112	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
209261005113	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
209261005114	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
209261005115	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
209261005116	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
209261005117	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
209261005118	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
209261005119	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
209261005120	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
209261005121	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
209261005122	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
209261005123	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
209261005124	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
209261005125	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
209261005126	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
209261005127	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
209261005128	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
209261005129	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
209261005130	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
209261005131	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
209261005132	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
209261005133	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
209261005134	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
209261005135	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
209261005136	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
209261005137	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
209261005138	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
209261005139	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
209261005140	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
209261005141	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
209261005142	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
209261005143	hypothetical protein; Provisional; Region: PRK11239
209261005144	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
209261005145	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
209261005146	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
209261005147	multidrug resistance protein MdtH; Provisional; Region: PRK11646
209261005148	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261005149	putative substrate translocation pore; other site
209261005150	glutaredoxin 2; Provisional; Region: PRK10387
209261005151	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
209261005152	C-terminal domain interface [polypeptide binding]; other site
209261005153	GSH binding site (G-site) [chemical binding]; other site
209261005154	catalytic residues [active]
209261005155	putative dimer interface [polypeptide binding]; other site
209261005156	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
209261005157	N-terminal domain interface [polypeptide binding]; other site
209261005158	lipoprotein; Provisional; Region: PRK10598
209261005159	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
209261005160	active site
209261005161	substrate binding pocket [chemical binding]; other site
209261005162	dimer interface [polypeptide binding]; other site
209261005163	DNA damage-inducible protein I; Provisional; Region: PRK10597
209261005164	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
209261005165	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
209261005166	hydroxyglutarate oxidase; Provisional; Region: PRK11728
209261005167	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
209261005168	hypothetical protein; Provisional; Region: PRK03757
209261005169	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
209261005170	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
209261005171	active site residue [active]
209261005172	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
209261005173	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
209261005174	putative acyl-acceptor binding pocket; other site
209261005175	drug efflux system protein MdtG; Provisional; Region: PRK09874
209261005176	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261005177	putative substrate translocation pore; other site
209261005178	secY/secA suppressor protein; Provisional; Region: PRK11467
209261005179	lipoprotein; Provisional; Region: PRK10175
209261005180	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
209261005181	Ligand binding site; other site
209261005182	DXD motif; other site
209261005183	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
209261005184	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
209261005185	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
209261005186	Acyltransferase family; Region: Acyl_transf_3; pfam01757
209261005187	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
209261005188	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
209261005189	putative active site [active]
209261005190	catalytic site [active]
209261005191	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
209261005192	putative active site [active]
209261005193	catalytic site [active]
209261005194	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
209261005195	putative ADP-ribose binding site [chemical binding]; other site
209261005196	putative active site [active]
209261005197	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
209261005198	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
209261005199	major curlin subunit; Provisional; Region: csgA; PRK10051
209261005200	Curlin associated repeat; Region: Curlin_rpt; pfam07012
209261005201	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
209261005202	Curlin associated repeat; Region: Curlin_rpt; pfam07012
209261005203	Curlin associated repeat; Region: Curlin_rpt; pfam07012
209261005204	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
209261005205	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261005206	DNA binding residues [nucleotide binding]
209261005207	dimerization interface [polypeptide binding]; other site
209261005208	curli assembly protein CsgE; Provisional; Region: PRK10386
209261005209	curli assembly protein CsgF; Provisional; Region: PRK10050
209261005210	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
209261005211	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
209261005212	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
209261005213	putative hydrolase; Validated; Region: PRK09248
209261005214	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
209261005215	active site
209261005216	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
209261005217	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
209261005218	putative ligand binding site [chemical binding]; other site
209261005219	NAD binding site [chemical binding]; other site
209261005220	dimerization interface [polypeptide binding]; other site
209261005221	catalytic site [active]
209261005222	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
209261005223	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
209261005224	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
209261005225	putative sialic acid transporter; Provisional; Region: PRK12307
209261005226	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261005227	putative substrate translocation pore; other site
209261005228	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
209261005229	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
209261005230	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
209261005231	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
209261005232	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
209261005233	putative active site cavity [active]
209261005234	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
209261005235	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
209261005236	Na binding site [ion binding]; other site
209261005237	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
209261005238	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
209261005239	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
209261005240	putative active site [active]
209261005241	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
209261005242	hypothetical protein; Provisional; Region: PRK10536
209261005243	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
209261005244	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
209261005245	Na binding site [ion binding]; other site
209261005246	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
209261005247	Predicted transcriptional regulator [Transcription]; Region: COG3905
209261005248	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
209261005249	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
209261005250	Glutamate binding site [chemical binding]; other site
209261005251	NAD binding site [chemical binding]; other site
209261005252	catalytic residues [active]
209261005253	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
209261005254	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
209261005255	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261005256	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
209261005257	General stress protein [General function prediction only]; Region: GsiB; COG3729
209261005258	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
209261005259	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
209261005260	hypothetical protein; Provisional; Region: PRK10174
209261005261	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
209261005262	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
209261005263	catalytic core [active]
209261005264	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
209261005265	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
209261005266	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
209261005267	catalytic residues [active]
209261005268	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
209261005269	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
209261005270	catalytic residues [active]
209261005271	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
209261005272	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
209261005273	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
209261005274	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
209261005275	DsbD alpha interface [polypeptide binding]; other site
209261005276	catalytic residues [active]
209261005277	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
209261005278	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
209261005279	HSP70 interaction site [polypeptide binding]; other site
209261005280	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
209261005281	substrate binding site [polypeptide binding]; other site
209261005282	dimer interface [polypeptide binding]; other site
209261005283	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
209261005284	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
209261005285	anti-adapter protein IraM; Provisional; Region: PRK09919
209261005286	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
209261005287	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
209261005288	Cupin domain; Region: Cupin_2; pfam07883
209261005289	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261005290	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261005291	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
209261005292	putative substrate translocation pore; other site
209261005293	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
209261005294	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
209261005295	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
209261005296	putative substrate binding pocket [chemical binding]; other site
209261005297	trimer interface [polypeptide binding]; other site
209261005298	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
209261005299	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
209261005300	putative active site [active]
209261005301	putative metal binding site [ion binding]; other site
209261005302	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
209261005303	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
209261005304	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
209261005305	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
209261005306	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
209261005307	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
209261005308	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
209261005309	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
209261005310	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
209261005311	active site
209261005312	homotetramer interface [polypeptide binding]; other site
209261005313	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
209261005314	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261005315	active site
209261005316	phosphorylation site [posttranslational modification]
209261005317	intermolecular recognition site; other site
209261005318	dimerization interface [polypeptide binding]; other site
209261005319	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261005320	DNA binding site [nucleotide binding]
209261005321	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
209261005322	HAMP domain; Region: HAMP; pfam00672
209261005323	dimerization interface [polypeptide binding]; other site
209261005324	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261005325	dimer interface [polypeptide binding]; other site
209261005326	phosphorylation site [posttranslational modification]
209261005327	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261005328	ATP binding site [chemical binding]; other site
209261005329	Mg2+ binding site [ion binding]; other site
209261005330	G-X-G motif; other site
209261005331	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
209261005332	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
209261005333	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
209261005334	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
209261005335	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
209261005336	secreted effector protein PipB; Provisional; Region: PRK15197
209261005337	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
209261005338	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
209261005339	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
209261005340	PipA protein; Region: PipA; pfam07108
209261005341	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261005342	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
209261005343	YccA-like proteins; Region: YccA_like; cd10433
209261005344	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
209261005345	sulfur transfer protein TusE; Provisional; Region: PRK11508
209261005346	acylphosphatase; Provisional; Region: PRK14426
209261005347	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261005348	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
209261005349	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
209261005350	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
209261005351	putative RNA binding site [nucleotide binding]; other site
209261005352	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261005353	S-adenosylmethionine binding site [chemical binding]; other site
209261005354	heat shock protein HspQ; Provisional; Region: PRK14129
209261005355	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
209261005356	hypothetical protein; Provisional; Region: PRK03641
209261005357	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
209261005358	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
209261005359	active site
209261005360	dimer interfaces [polypeptide binding]; other site
209261005361	catalytic residues [active]
209261005362	DNA helicase IV; Provisional; Region: helD; PRK11054
209261005363	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
209261005364	Part of AAA domain; Region: AAA_19; pfam13245
209261005365	Family description; Region: UvrD_C_2; pfam13538
209261005366	Predicted membrane protein [Function unknown]; Region: COG3304
209261005367	Domain of unknown function (DUF307); Region: DUF307; pfam03733
209261005368	Domain of unknown function (DUF307); Region: DUF307; pfam03733
209261005369	TIGR01666 family membrane protein; Region: YCCS
209261005370	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
209261005371	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
209261005372	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
209261005373	TfoX C-terminal domain; Region: TfoX_C; pfam04994
209261005374	cell division inhibitor SulA; Region: sula; TIGR00623
209261005375	outer membrane protein A; Reviewed; Region: PRK10808
209261005376	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
209261005377	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
209261005378	ligand binding site [chemical binding]; other site
209261005379	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
209261005380	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
209261005381	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
209261005382	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
209261005383	active site 1 [active]
209261005384	dimer interface [polypeptide binding]; other site
209261005385	active site 2 [active]
209261005386	ribosome modulation factor; Provisional; Region: PRK14563
209261005387	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
209261005388	Protein of unknown function (DUF330); Region: DUF330; pfam03886
209261005389	paraquat-inducible protein B; Provisional; Region: PRK10807
209261005390	mce related protein; Region: MCE; pfam02470
209261005391	mce related protein; Region: MCE; pfam02470
209261005392	mce related protein; Region: MCE; pfam02470
209261005393	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
209261005394	Paraquat-inducible protein A; Region: PqiA; pfam04403
209261005395	Paraquat-inducible protein A; Region: PqiA; pfam04403
209261005396	ABC transporter ATPase component; Reviewed; Region: PRK11147
209261005397	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261005398	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261005399	Walker A/P-loop; other site
209261005400	Walker A/P-loop; other site
209261005401	ATP binding site [chemical binding]; other site
209261005402	ATP binding site [chemical binding]; other site
209261005403	Q-loop/lid; other site
209261005404	Q-loop/lid; other site
209261005405	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
209261005406	ABC transporter signature motif; other site
209261005407	Walker B; other site
209261005408	D-loop; other site
209261005409	ABC transporter; Region: ABC_tran_2; pfam12848
209261005410	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
209261005411	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
209261005412	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
209261005413	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
209261005414	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261005415	S-adenosylmethionine binding site [chemical binding]; other site
209261005416	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
209261005417	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
209261005418	MOSC domain; Region: MOSC; pfam03473
209261005419	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
209261005420	catalytic loop [active]
209261005421	iron binding site [ion binding]; other site
209261005422	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
209261005423	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
209261005424	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
209261005425	quinone interaction residues [chemical binding]; other site
209261005426	active site
209261005427	catalytic residues [active]
209261005428	FMN binding site [chemical binding]; other site
209261005429	substrate binding site [chemical binding]; other site
209261005430	aminopeptidase N; Provisional; Region: pepN; PRK14015
209261005431	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
209261005432	active site
209261005433	Zn binding site [ion binding]; other site
209261005434	DinI-like family; Region: DinI; cl11630
209261005435	Protein of unknown function (DUF1076); Region: DUF1076; pfam06416
209261005436	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
209261005437	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
209261005438	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
209261005439	Baseplate J-like protein; Region: Baseplate_J; cl01294
209261005440	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
209261005441	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
209261005442	HEPN domain; Region: HEPN; cl00824
209261005443	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
209261005444	virion protein; Provisional; Region: V; PHA02564
209261005445	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
209261005446	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
209261005447	Protein of unknown function (DUF4054); Region: DUF4054; pfam13262
209261005448	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834
209261005449	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
209261005450	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
209261005451	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
209261005452	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
209261005453	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
209261005454	Phage terminase large subunit; Region: Terminase_3; cl12054
209261005455	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
209261005456	Predicted chitinase [General function prediction only]; Region: COG3179
209261005457	Protein of unknown function (DUF754); Region: DUF754; pfam05449
209261005458	Antitermination protein; Region: Antiterm; pfam03589
209261005459	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
209261005460	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
209261005461	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
209261005462	DinI-like family; Region: DinI; pfam06183
209261005463	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
209261005464	Methyltransferase domain; Region: Methyltransf_25; pfam13649
209261005465	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
209261005466	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
209261005467	putative replication protein; Provisional; Region: PRK12377
209261005468	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261005469	Walker A motif; other site
209261005470	ATP binding site [chemical binding]; other site
209261005471	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
209261005472	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
209261005473	primosomal protein DnaI; Provisional; Region: PRK02854
209261005474	Bacteriophage CII protein; Region: Phage_CII; pfam05269
209261005475	transcriptional repressor DicA; Reviewed; Region: PRK09706
209261005476	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261005477	non-specific DNA binding site [nucleotide binding]; other site
209261005478	salt bridge; other site
209261005479	sequence-specific DNA binding site [nucleotide binding]; other site
209261005480	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
209261005481	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
209261005482	phage recombination protein Bet; Region: bet_lambda; TIGR01913
209261005483	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
209261005484	DNA-sulfur modification-associated; Region: DndB; pfam14072
209261005485	DGQHR domain; Region: DGQHR; TIGR03187
209261005486	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
209261005487	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
209261005488	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
209261005489	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
209261005490	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
209261005491	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
209261005492	Int/Topo IB signature motif; other site
209261005493	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
209261005494	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
209261005495	active site
209261005496	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
209261005497	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
209261005498	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
209261005499	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
209261005500	putative DNA binding site [nucleotide binding]; other site
209261005501	putative Zn2+ binding site [ion binding]; other site
209261005502	AsnC family; Region: AsnC_trans_reg; pfam01037
209261005503	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
209261005504	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
209261005505	putative dimer interface [polypeptide binding]; other site
209261005506	putative anticodon binding site; other site
209261005507	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
209261005508	homodimer interface [polypeptide binding]; other site
209261005509	motif 1; other site
209261005510	motif 2; other site
209261005511	active site
209261005512	motif 3; other site
209261005513	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
209261005514	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
209261005515	trimer interface [polypeptide binding]; other site
209261005516	eyelet of channel; other site
209261005517	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
209261005518	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261005519	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261005520	homodimer interface [polypeptide binding]; other site
209261005521	catalytic residue [active]
209261005522	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
209261005523	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
209261005524	Peptidase M15; Region: Peptidase_M15_3; cl01194
209261005525	murein L,D-transpeptidase; Provisional; Region: PRK10594
209261005526	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
209261005527	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
209261005528	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
209261005529	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
209261005530	P-loop containing region of AAA domain; Region: AAA_29; cl17516
209261005531	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
209261005532	condesin subunit E; Provisional; Region: PRK05256
209261005533	condesin subunit F; Provisional; Region: PRK05260
209261005534	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
209261005535	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261005536	S-adenosylmethionine binding site [chemical binding]; other site
209261005537	Uncharacterized conserved protein [Function unknown]; Region: COG1434
209261005538	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
209261005539	putative active site [active]
209261005540	hypothetical protein; Provisional; Region: PRK10593
209261005541	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
209261005542	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
209261005543	Ligand binding site; other site
209261005544	oligomer interface; other site
209261005545	hypothetical protein; Provisional; Region: PRK11827
209261005546	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
209261005547	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
209261005548	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
209261005549	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
209261005550	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
209261005551	Walker A/P-loop; other site
209261005552	ATP binding site [chemical binding]; other site
209261005553	Q-loop/lid; other site
209261005554	ABC transporter signature motif; other site
209261005555	Walker B; other site
209261005556	D-loop; other site
209261005557	H-loop/switch region; other site
209261005558	ComEC family competence protein; Provisional; Region: PRK11539
209261005559	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
209261005560	Competence protein; Region: Competence; pfam03772
209261005561	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
209261005562	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
209261005563	IHF dimer interface [polypeptide binding]; other site
209261005564	IHF - DNA interface [nucleotide binding]; other site
209261005565	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
209261005566	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
209261005567	RNA binding site [nucleotide binding]; other site
209261005568	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
209261005569	RNA binding site [nucleotide binding]; other site
209261005570	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
209261005571	RNA binding site [nucleotide binding]; other site
209261005572	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
209261005573	RNA binding site [nucleotide binding]; other site
209261005574	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
209261005575	RNA binding site [nucleotide binding]; other site
209261005576	cytidylate kinase; Provisional; Region: cmk; PRK00023
209261005577	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
209261005578	CMP-binding site; other site
209261005579	The sites determining sugar specificity; other site
209261005580	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
209261005581	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
209261005582	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
209261005583	hinge; other site
209261005584	active site
209261005585	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
209261005586	homodimer interface [polypeptide binding]; other site
209261005587	substrate-cofactor binding pocket; other site
209261005588	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261005589	catalytic residue [active]
209261005590	Predicted membrane protein [Function unknown]; Region: COG2323
209261005591	uncharacterized domain; Region: TIGR00702
209261005592	YcaO-like family; Region: YcaO; pfam02624
209261005593	formate transporter; Provisional; Region: PRK10805
209261005594	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
209261005595	Pyruvate formate lyase 1; Region: PFL1; cd01678
209261005596	coenzyme A binding site [chemical binding]; other site
209261005597	active site
209261005598	catalytic residues [active]
209261005599	glycine loop; other site
209261005600	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
209261005601	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261005602	FeS/SAM binding site; other site
209261005603	inner membrane transporter YjeM; Provisional; Region: PRK15238
209261005604	putative MFS family transporter protein; Provisional; Region: PRK03633
209261005605	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261005606	putative substrate translocation pore; other site
209261005607	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
209261005608	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
209261005609	4Fe-4S binding domain; Region: Fer4; pfam00037
209261005610	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
209261005611	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
209261005612	putative [Fe4-S4] binding site [ion binding]; other site
209261005613	putative molybdopterin cofactor binding site [chemical binding]; other site
209261005614	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
209261005615	putative molybdopterin cofactor binding site; other site
209261005616	seryl-tRNA synthetase; Provisional; Region: PRK05431
209261005617	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
209261005618	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
209261005619	dimer interface [polypeptide binding]; other site
209261005620	active site
209261005621	motif 1; other site
209261005622	motif 2; other site
209261005623	motif 3; other site
209261005624	recombination factor protein RarA; Reviewed; Region: PRK13342
209261005625	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261005626	Walker A motif; other site
209261005627	ATP binding site [chemical binding]; other site
209261005628	Walker B motif; other site
209261005629	arginine finger; other site
209261005630	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
209261005631	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
209261005632	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
209261005633	DNA translocase FtsK; Provisional; Region: PRK10263
209261005634	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
209261005635	DNA translocase FtsK; Provisional; Region: PRK10263
209261005636	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
209261005637	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
209261005638	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
209261005639	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
209261005640	putative DNA binding site [nucleotide binding]; other site
209261005641	putative Zn2+ binding site [ion binding]; other site
209261005642	AsnC family; Region: AsnC_trans_reg; pfam01037
209261005643	thioredoxin reductase; Provisional; Region: PRK10262
209261005644	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
209261005645	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261005646	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
209261005647	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
209261005648	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261005649	Walker A/P-loop; other site
209261005650	ATP binding site [chemical binding]; other site
209261005651	Q-loop/lid; other site
209261005652	ABC transporter signature motif; other site
209261005653	Walker B; other site
209261005654	D-loop; other site
209261005655	H-loop/switch region; other site
209261005656	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
209261005657	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
209261005658	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261005659	Walker A/P-loop; other site
209261005660	ATP binding site [chemical binding]; other site
209261005661	Q-loop/lid; other site
209261005662	ABC transporter signature motif; other site
209261005663	Walker B; other site
209261005664	D-loop; other site
209261005665	H-loop/switch region; other site
209261005666	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
209261005667	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
209261005668	rRNA binding site [nucleotide binding]; other site
209261005669	predicted 30S ribosome binding site; other site
209261005670	LysR family transcriptional regulator; Provisional; Region: PRK14997
209261005671	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261005672	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
209261005673	putative effector binding pocket; other site
209261005674	putative dimerization interface [polypeptide binding]; other site
209261005675	Pirin-related protein [General function prediction only]; Region: COG1741
209261005676	Pirin; Region: Pirin; pfam02678
209261005677	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
209261005678	Isochorismatase family; Region: Isochorismatase; pfam00857
209261005679	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
209261005680	catalytic triad [active]
209261005681	dimer interface [polypeptide binding]; other site
209261005682	conserved cis-peptide bond; other site
209261005683	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
209261005684	DNA binding site [nucleotide binding]
209261005685	active site
209261005686	Int/Topo IB signature motif; other site
209261005687	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
209261005688	Clp amino terminal domain; Region: Clp_N; pfam02861
209261005689	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261005690	Walker A motif; other site
209261005691	ATP binding site [chemical binding]; other site
209261005692	Walker B motif; other site
209261005693	arginine finger; other site
209261005694	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261005695	Walker A motif; other site
209261005696	ATP binding site [chemical binding]; other site
209261005697	Walker B motif; other site
209261005698	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
209261005699	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
209261005700	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
209261005701	DNA-binding site [nucleotide binding]; DNA binding site
209261005702	RNA-binding motif; other site
209261005703	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
209261005704	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
209261005705	Walker A/P-loop; other site
209261005706	ATP binding site [chemical binding]; other site
209261005707	Q-loop/lid; other site
209261005708	ABC transporter signature motif; other site
209261005709	Walker B; other site
209261005710	D-loop; other site
209261005711	H-loop/switch region; other site
209261005712	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
209261005713	FtsX-like permease family; Region: FtsX; pfam02687
209261005714	macrolide transporter subunit MacA; Provisional; Region: PRK11578
209261005715	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
209261005716	HlyD family secretion protein; Region: HlyD_3; pfam13437
209261005717	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
209261005718	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
209261005719	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
209261005720	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
209261005721	putative active site [active]
209261005722	putative metal-binding site [ion binding]; other site
209261005723	Predicted membrane protein [Function unknown]; Region: COG2431
209261005724	hybrid cluster protein; Provisional; Region: PRK05290
209261005725	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
209261005726	ACS interaction site; other site
209261005727	CODH interaction site; other site
209261005728	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
209261005729	hybrid metal cluster; other site
209261005730	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
209261005731	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
209261005732	FAD binding pocket [chemical binding]; other site
209261005733	FAD binding motif [chemical binding]; other site
209261005734	phosphate binding motif [ion binding]; other site
209261005735	beta-alpha-beta structure motif; other site
209261005736	NAD binding pocket [chemical binding]; other site
209261005737	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
209261005738	catalytic loop [active]
209261005739	iron binding site [ion binding]; other site
209261005740	pyruvate dehydrogenase; Provisional; Region: PRK09124
209261005741	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
209261005742	PYR/PP interface [polypeptide binding]; other site
209261005743	dimer interface [polypeptide binding]; other site
209261005744	tetramer interface [polypeptide binding]; other site
209261005745	TPP binding site [chemical binding]; other site
209261005746	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
209261005747	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
209261005748	TPP-binding site [chemical binding]; other site
209261005749	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
209261005750	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
209261005751	tetramer interface [polypeptide binding]; other site
209261005752	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261005753	catalytic residue [active]
209261005754	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
209261005755	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
209261005756	putative NAD(P) binding site [chemical binding]; other site
209261005757	putative active site [active]
209261005758	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
209261005759	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
209261005760	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
209261005761	NAD(P) binding site [chemical binding]; other site
209261005762	active site
209261005763	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
209261005764	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
209261005765	amidase catalytic site [active]
209261005766	Zn binding residues [ion binding]; other site
209261005767	substrate binding site [chemical binding]; other site
209261005768	hypothetical protein; Provisional; Region: PRK02877
209261005769	putative lipoprotein; Provisional; Region: PRK10533
209261005770	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
209261005771	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261005772	Walker A/P-loop; other site
209261005773	ATP binding site [chemical binding]; other site
209261005774	Q-loop/lid; other site
209261005775	ABC transporter signature motif; other site
209261005776	Walker B; other site
209261005777	D-loop; other site
209261005778	H-loop/switch region; other site
209261005779	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
209261005780	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261005781	substrate binding pocket [chemical binding]; other site
209261005782	membrane-bound complex binding site; other site
209261005783	hinge residues; other site
209261005784	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
209261005785	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261005786	dimer interface [polypeptide binding]; other site
209261005787	conserved gate region; other site
209261005788	putative PBP binding loops; other site
209261005789	ABC-ATPase subunit interface; other site
209261005790	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261005791	dimer interface [polypeptide binding]; other site
209261005792	conserved gate region; other site
209261005793	putative PBP binding loops; other site
209261005794	ABC-ATPase subunit interface; other site
209261005795	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
209261005796	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261005797	substrate binding pocket [chemical binding]; other site
209261005798	membrane-bound complex binding site; other site
209261005799	hinge residues; other site
209261005800	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
209261005801	Sulfatase; Region: Sulfatase; cl17466
209261005802	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
209261005803	active site
209261005804	P-loop; other site
209261005805	phosphorylation site [posttranslational modification]
209261005806	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
209261005807	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
209261005808	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261005809	S-adenosylmethionine binding site [chemical binding]; other site
209261005810	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
209261005811	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
209261005812	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261005813	dimer interface [polypeptide binding]; other site
209261005814	conserved gate region; other site
209261005815	putative PBP binding loops; other site
209261005816	ABC-ATPase subunit interface; other site
209261005817	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261005818	dimer interface [polypeptide binding]; other site
209261005819	conserved gate region; other site
209261005820	putative PBP binding loops; other site
209261005821	ABC-ATPase subunit interface; other site
209261005822	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
209261005823	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261005824	Walker A/P-loop; other site
209261005825	ATP binding site [chemical binding]; other site
209261005826	Q-loop/lid; other site
209261005827	ABC transporter signature motif; other site
209261005828	Walker B; other site
209261005829	D-loop; other site
209261005830	H-loop/switch region; other site
209261005831	TOBE domain; Region: TOBE_2; pfam08402
209261005832	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
209261005833	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
209261005834	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
209261005835	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
209261005836	RimK-like ATP-grasp domain; Region: RimK; pfam08443
209261005837	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
209261005838	dimer interface [polypeptide binding]; other site
209261005839	FMN binding site [chemical binding]; other site
209261005840	NADPH bind site [chemical binding]; other site
209261005841	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
209261005842	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
209261005843	GSH binding site [chemical binding]; other site
209261005844	catalytic residues [active]
209261005845	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
209261005846	putative transporter; Provisional; Region: PRK04972
209261005847	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
209261005848	TrkA-C domain; Region: TrkA_C; pfam02080
209261005849	TrkA-C domain; Region: TrkA_C; pfam02080
209261005850	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
209261005851	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
209261005852	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261005853	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
209261005854	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261005855	putative substrate translocation pore; other site
209261005856	Major Facilitator Superfamily; Region: MFS_1; pfam07690
209261005857	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
209261005858	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261005859	active site
209261005860	motif I; other site
209261005861	motif II; other site
209261005862	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261005863	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
209261005864	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261005865	putative substrate translocation pore; other site
209261005866	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
209261005867	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
209261005868	active site
209261005869	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
209261005870	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
209261005871	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261005872	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
209261005873	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
209261005874	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
209261005875	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
209261005876	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
209261005877	putative C-terminal domain interface [polypeptide binding]; other site
209261005878	putative GSH binding site (G-site) [chemical binding]; other site
209261005879	putative dimer interface [polypeptide binding]; other site
209261005880	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
209261005881	putative N-terminal domain interface [polypeptide binding]; other site
209261005882	putative dimer interface [polypeptide binding]; other site
209261005883	putative substrate binding pocket (H-site) [chemical binding]; other site
209261005884	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
209261005885	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
209261005886	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
209261005887	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
209261005888	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
209261005889	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261005890	FeS/SAM binding site; other site
209261005891	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
209261005892	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
209261005893	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261005894	dimer interface [polypeptide binding]; other site
209261005895	conserved gate region; other site
209261005896	putative PBP binding loops; other site
209261005897	ABC-ATPase subunit interface; other site
209261005898	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
209261005899	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261005900	dimer interface [polypeptide binding]; other site
209261005901	conserved gate region; other site
209261005902	putative PBP binding loops; other site
209261005903	ABC-ATPase subunit interface; other site
209261005904	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
209261005905	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
209261005906	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
209261005907	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261005908	Walker A/P-loop; other site
209261005909	ATP binding site [chemical binding]; other site
209261005910	Q-loop/lid; other site
209261005911	ABC transporter signature motif; other site
209261005912	Walker B; other site
209261005913	D-loop; other site
209261005914	H-loop/switch region; other site
209261005915	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
209261005916	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261005917	Walker A/P-loop; other site
209261005918	ATP binding site [chemical binding]; other site
209261005919	Q-loop/lid; other site
209261005920	ABC transporter signature motif; other site
209261005921	Walker B; other site
209261005922	D-loop; other site
209261005923	H-loop/switch region; other site
209261005924	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
209261005925	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
209261005926	catalytic nucleophile [active]
209261005927	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
209261005928	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
209261005929	dimer interface [polypeptide binding]; other site
209261005930	putative functional site; other site
209261005931	putative MPT binding site; other site
209261005932	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
209261005933	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
209261005934	ATP binding site [chemical binding]; other site
209261005935	substrate interface [chemical binding]; other site
209261005936	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
209261005937	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261005938	FeS/SAM binding site; other site
209261005939	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
209261005940	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
209261005941	dimer interface [polypeptide binding]; other site
209261005942	active site
209261005943	glycine loop; other site
209261005944	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
209261005945	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261005946	active site
209261005947	motif I; other site
209261005948	motif II; other site
209261005949	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261005950	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
209261005951	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
209261005952	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
209261005953	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261005954	Walker A/P-loop; other site
209261005955	ATP binding site [chemical binding]; other site
209261005956	ABC transporter signature motif; other site
209261005957	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
209261005958	Walker B; other site
209261005959	ABC transporter; Region: ABC_tran_2; pfam12848
209261005960	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
209261005961	L,D-transpeptidase; Provisional; Region: PRK10260
209261005962	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
209261005963	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
209261005964	transmembrane helices; other site
209261005965	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
209261005966	manganese transport regulator MntR; Provisional; Region: PRK11050
209261005967	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
209261005968	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
209261005969	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
209261005970	Sulfatase; Region: Sulfatase; pfam00884
209261005971	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261005972	outer membrane protein X; Provisional; Region: ompX; PRK09408
209261005973	threonine and homoserine efflux system; Provisional; Region: PRK10532
209261005974	EamA-like transporter family; Region: EamA; pfam00892
209261005975	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
209261005976	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
209261005977	dimerization interface [polypeptide binding]; other site
209261005978	DPS ferroxidase diiron center [ion binding]; other site
209261005979	ion pore; other site
209261005980	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
209261005981	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261005982	substrate binding pocket [chemical binding]; other site
209261005983	membrane-bound complex binding site; other site
209261005984	hinge residues; other site
209261005985	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
209261005986	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261005987	dimer interface [polypeptide binding]; other site
209261005988	conserved gate region; other site
209261005989	putative PBP binding loops; other site
209261005990	ABC-ATPase subunit interface; other site
209261005991	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
209261005992	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
209261005993	Walker A/P-loop; other site
209261005994	ATP binding site [chemical binding]; other site
209261005995	Q-loop/lid; other site
209261005996	ABC transporter signature motif; other site
209261005997	Walker B; other site
209261005998	D-loop; other site
209261005999	H-loop/switch region; other site
209261006000	putative mechanosensitive channel protein; Provisional; Region: PRK11465
209261006001	Mechanosensitive ion channel; Region: MS_channel; pfam00924
209261006002	hypothetical protein; Provisional; Region: PRK11019
209261006003	hypothetical protein; Provisional; Region: PRK10259
209261006004	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
209261006005	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
209261006006	ATP binding site [chemical binding]; other site
209261006007	Mg++ binding site [ion binding]; other site
209261006008	motif III; other site
209261006009	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261006010	nucleotide binding region [chemical binding]; other site
209261006011	ATP-binding site [chemical binding]; other site
209261006012	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
209261006013	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261006014	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
209261006015	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
209261006016	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
209261006017	HlyD family secretion protein; Region: HlyD_3; pfam13437
209261006018	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
209261006019	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
209261006020	Walker A/P-loop; other site
209261006021	ATP binding site [chemical binding]; other site
209261006022	Q-loop/lid; other site
209261006023	ABC transporter signature motif; other site
209261006024	Walker B; other site
209261006025	D-loop; other site
209261006026	H-loop/switch region; other site
209261006027	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
209261006028	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
209261006029	Walker A/P-loop; other site
209261006030	ATP binding site [chemical binding]; other site
209261006031	Q-loop/lid; other site
209261006032	ABC transporter signature motif; other site
209261006033	Walker B; other site
209261006034	D-loop; other site
209261006035	H-loop/switch region; other site
209261006036	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
209261006037	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
209261006038	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
209261006039	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
209261006040	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
209261006041	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
209261006042	putative catalytic site [active]
209261006043	putative metal binding site [ion binding]; other site
209261006044	putative phosphate binding site [ion binding]; other site
209261006045	cardiolipin synthase 2; Provisional; Region: PRK11263
209261006046	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
209261006047	putative active site [active]
209261006048	catalytic site [active]
209261006049	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
209261006050	putative active site [active]
209261006051	catalytic site [active]
209261006052	Predicted integral membrane protein [Function unknown]; Region: COG0392
209261006053	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
209261006054	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
209261006055	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
209261006056	MoaE homodimer interface [polypeptide binding]; other site
209261006057	MoaD interaction [polypeptide binding]; other site
209261006058	active site residues [active]
209261006059	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
209261006060	MoaE interaction surface [polypeptide binding]; other site
209261006061	MoeB interaction surface [polypeptide binding]; other site
209261006062	thiocarboxylated glycine; other site
209261006063	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
209261006064	trimer interface [polypeptide binding]; other site
209261006065	dimer interface [polypeptide binding]; other site
209261006066	putative active site [active]
209261006067	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
209261006068	MPT binding site; other site
209261006069	trimer interface [polypeptide binding]; other site
209261006070	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
209261006071	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261006072	FeS/SAM binding site; other site
209261006073	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
209261006074	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
209261006075	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
209261006076	putative substrate binding pocket [chemical binding]; other site
209261006077	dimer interface [polypeptide binding]; other site
209261006078	phosphate binding site [ion binding]; other site
209261006079	excinuclease ABC subunit B; Provisional; Region: PRK05298
209261006080	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261006081	ATP binding site [chemical binding]; other site
209261006082	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261006083	nucleotide binding region [chemical binding]; other site
209261006084	ATP-binding site [chemical binding]; other site
209261006085	Ultra-violet resistance protein B; Region: UvrB; pfam12344
209261006086	UvrB/uvrC motif; Region: UVR; pfam02151
209261006087	AAA domain; Region: AAA_26; pfam13500
209261006088	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
209261006089	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
209261006090	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261006091	S-adenosylmethionine binding site [chemical binding]; other site
209261006092	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
209261006093	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
209261006094	substrate-cofactor binding pocket; other site
209261006095	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261006096	catalytic residue [active]
209261006097	biotin synthase; Provisional; Region: PRK15108
209261006098	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261006099	FeS/SAM binding site; other site
209261006100	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
209261006101	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
209261006102	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
209261006103	inhibitor-cofactor binding pocket; inhibition site
209261006104	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261006105	catalytic residue [active]
209261006106	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
209261006107	substrate binding site [chemical binding]; other site
209261006108	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
209261006109	active sites [active]
209261006110	tetramer interface [polypeptide binding]; other site
209261006111	urocanate hydratase; Provisional; Region: PRK05414
209261006112	histidine utilization repressor; Provisional; Region: PRK14999
209261006113	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261006114	DNA-binding site [nucleotide binding]; DNA binding site
209261006115	UTRA domain; Region: UTRA; pfam07702
209261006116	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
209261006117	putative active site [active]
209261006118	putative metal binding site [ion binding]; other site
209261006119	imidazolonepropionase; Validated; Region: PRK09356
209261006120	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
209261006121	active site
209261006122	acyl-CoA thioesterase; Provisional; Region: PRK10531
209261006123	putative pectinesterase; Region: PLN02432; cl01911
209261006124	6-phosphogluconolactonase; Provisional; Region: PRK11028
209261006125	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
209261006126	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261006127	active site
209261006128	motif I; other site
209261006129	motif II; other site
209261006130	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261006131	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
209261006132	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261006133	Walker A/P-loop; other site
209261006134	ATP binding site [chemical binding]; other site
209261006135	Q-loop/lid; other site
209261006136	ABC transporter signature motif; other site
209261006137	Walker B; other site
209261006138	D-loop; other site
209261006139	H-loop/switch region; other site
209261006140	molybdenum-pterin binding domain; Region: Mop; TIGR00638
209261006141	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
209261006142	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261006143	dimer interface [polypeptide binding]; other site
209261006144	conserved gate region; other site
209261006145	putative PBP binding loops; other site
209261006146	ABC-ATPase subunit interface; other site
209261006147	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
209261006148	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261006149	substrate binding pocket [chemical binding]; other site
209261006150	membrane-bound complex binding site; other site
209261006151	hinge residues; other site
209261006152	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
209261006153	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
209261006154	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
209261006155	molybdenum-pterin binding domain; Region: Mop; TIGR00638
209261006156	TOBE domain; Region: TOBE; pfam03459
209261006157	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
209261006158	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261006159	Walker A/P-loop; other site
209261006160	ATP binding site [chemical binding]; other site
209261006161	Q-loop/lid; other site
209261006162	ABC transporter signature motif; other site
209261006163	Walker B; other site
209261006164	D-loop; other site
209261006165	H-loop/switch region; other site
209261006166	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261006167	Walker A/P-loop; other site
209261006168	ATP binding site [chemical binding]; other site
209261006169	Q-loop/lid; other site
209261006170	ABC transporter signature motif; other site
209261006171	Walker B; other site
209261006172	D-loop; other site
209261006173	H-loop/switch region; other site
209261006174	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
209261006175	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
209261006176	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
209261006177	NAD binding site [chemical binding]; other site
209261006178	homodimer interface [polypeptide binding]; other site
209261006179	active site
209261006180	substrate binding site [chemical binding]; other site
209261006181	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
209261006182	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
209261006183	dimer interface [polypeptide binding]; other site
209261006184	active site
209261006185	galactokinase; Provisional; Region: PRK05101
209261006186	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
209261006187	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
209261006188	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
209261006189	active site
209261006190	catalytic residues [active]
209261006191	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
209261006192	catalytic core [active]
209261006193	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
209261006194	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
209261006195	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
209261006196	Walker A/P-loop; other site
209261006197	ATP binding site [chemical binding]; other site
209261006198	Q-loop/lid; other site
209261006199	ABC transporter signature motif; other site
209261006200	Walker B; other site
209261006201	D-loop; other site
209261006202	H-loop/switch region; other site
209261006203	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
209261006204	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
209261006205	dimer interface [polypeptide binding]; other site
209261006206	putative PBP binding regions; other site
209261006207	ABC-ATPase subunit  interface; other site
209261006208	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
209261006209	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
209261006210	YbgS-like protein; Region: YbgS; pfam13985
209261006211	zinc transporter ZitB; Provisional; Region: PRK03557
209261006212	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
209261006213	quinolinate synthetase; Provisional; Region: PRK09375
209261006214	tol-pal system protein YbgF; Provisional; Region: PRK10803
209261006215	Tetratricopeptide repeat; Region: TPR_6; pfam13174
209261006216	Tetratricopeptide repeat; Region: TPR_6; pfam13174
209261006217	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
209261006218	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
209261006219	ligand binding site [chemical binding]; other site
209261006220	translocation protein TolB; Provisional; Region: tolB; PRK03629
209261006221	TolB amino-terminal domain; Region: TolB_N; pfam04052
209261006222	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
209261006223	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
209261006224	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
209261006225	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
209261006226	TolA C-terminal; Region: TolA; pfam06519
209261006227	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
209261006228	colicin uptake protein TolR; Provisional; Region: PRK11024
209261006229	colicin uptake protein TolQ; Provisional; Region: PRK10801
209261006230	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
209261006231	active site
209261006232	hypothetical protein; Provisional; Region: PRK10588
209261006233	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
209261006234	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
209261006235	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
209261006236	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
209261006237	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
209261006238	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
209261006239	CoA binding domain; Region: CoA_binding; smart00881
209261006240	CoA-ligase; Region: Ligase_CoA; pfam00549
209261006241	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
209261006242	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
209261006243	CoA-ligase; Region: Ligase_CoA; pfam00549
209261006244	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
209261006245	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
209261006246	E3 interaction surface; other site
209261006247	lipoyl attachment site [posttranslational modification]; other site
209261006248	e3 binding domain; Region: E3_binding; pfam02817
209261006249	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
209261006250	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
209261006251	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
209261006252	TPP-binding site [chemical binding]; other site
209261006253	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
209261006254	dimer interface [polypeptide binding]; other site
209261006255	PYR/PP interface [polypeptide binding]; other site
209261006256	TPP binding site [chemical binding]; other site
209261006257	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
209261006258	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
209261006259	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
209261006260	L-aspartate oxidase; Provisional; Region: PRK06175
209261006261	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
209261006262	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
209261006263	SdhC subunit interface [polypeptide binding]; other site
209261006264	proximal heme binding site [chemical binding]; other site
209261006265	cardiolipin binding site; other site
209261006266	Iron-sulfur protein interface; other site
209261006267	proximal quinone binding site [chemical binding]; other site
209261006268	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
209261006269	Iron-sulfur protein interface; other site
209261006270	proximal quinone binding site [chemical binding]; other site
209261006271	SdhD (CybS) interface [polypeptide binding]; other site
209261006272	proximal heme binding site [chemical binding]; other site
209261006273	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
209261006274	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
209261006275	dimer interface [polypeptide binding]; other site
209261006276	active site
209261006277	citrylCoA binding site [chemical binding]; other site
209261006278	NADH binding [chemical binding]; other site
209261006279	cationic pore residues; other site
209261006280	oxalacetate/citrate binding site [chemical binding]; other site
209261006281	coenzyme A binding site [chemical binding]; other site
209261006282	catalytic triad [active]
209261006283	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
209261006284	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
209261006285	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
209261006286	endonuclease VIII; Provisional; Region: PRK10445
209261006287	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
209261006288	DNA binding site [nucleotide binding]
209261006289	catalytic residue [active]
209261006290	putative catalytic residues [active]
209261006291	H2TH interface [polypeptide binding]; other site
209261006292	intercalation triad [nucleotide binding]; other site
209261006293	substrate specificity determining residue; other site
209261006294	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
209261006295	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
209261006296	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
209261006297	active site
209261006298	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
209261006299	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
209261006300	Walker A/P-loop; other site
209261006301	ATP binding site [chemical binding]; other site
209261006302	Q-loop/lid; other site
209261006303	ABC transporter signature motif; other site
209261006304	Walker B; other site
209261006305	D-loop; other site
209261006306	H-loop/switch region; other site
209261006307	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
209261006308	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
209261006309	putative ADP-binding pocket [chemical binding]; other site
209261006310	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
209261006311	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
209261006312	active site
209261006313	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
209261006314	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
209261006315	UDP-galactopyranose mutase; Region: GLF; pfam03275
209261006316	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
209261006317	active site
209261006318	DNA binding site [nucleotide binding]
209261006319	Int/Topo IB signature motif; other site
209261006320	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
209261006321	putative active site [active]
209261006322	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
209261006323	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
209261006324	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
209261006325	Uncharacterized conserved protein [Function unknown]; Region: COG0327
209261006326	metal-binding protein; Provisional; Region: PRK10799
209261006327	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
209261006328	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261006329	putative substrate translocation pore; other site
209261006330	POT family; Region: PTR2; pfam00854
209261006331	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
209261006332	DNA photolyase; Region: DNA_photolyase; pfam00875
209261006333	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
209261006334	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
209261006335	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
209261006336	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
209261006337	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
209261006338	sensor protein KdpD; Provisional; Region: PRK10490
209261006339	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
209261006340	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
209261006341	Ligand Binding Site [chemical binding]; other site
209261006342	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
209261006343	GAF domain; Region: GAF_3; pfam13492
209261006344	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261006345	dimer interface [polypeptide binding]; other site
209261006346	phosphorylation site [posttranslational modification]
209261006347	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261006348	ATP binding site [chemical binding]; other site
209261006349	Mg2+ binding site [ion binding]; other site
209261006350	G-X-G motif; other site
209261006351	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
209261006352	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261006353	active site
209261006354	phosphorylation site [posttranslational modification]
209261006355	intermolecular recognition site; other site
209261006356	dimerization interface [polypeptide binding]; other site
209261006357	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261006358	DNA binding site [nucleotide binding]
209261006359	putrescine transporter; Provisional; Region: potE; PRK10655
209261006360	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
209261006361	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
209261006362	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
209261006363	active site
209261006364	substrate binding site [chemical binding]; other site
209261006365	metal binding site [ion binding]; metal-binding site
209261006366	replication initiation regulator SeqA; Provisional; Region: PRK11187
209261006367	acyl-CoA esterase; Provisional; Region: PRK10673
209261006368	PGAP1-like protein; Region: PGAP1; pfam07819
209261006369	LexA regulated protein; Provisional; Region: PRK11675
209261006370	flavodoxin FldA; Validated; Region: PRK09267
209261006371	ferric uptake regulator; Provisional; Region: fur; PRK09462
209261006372	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
209261006373	metal binding site 2 [ion binding]; metal-binding site
209261006374	putative DNA binding helix; other site
209261006375	metal binding site 1 [ion binding]; metal-binding site
209261006376	dimer interface [polypeptide binding]; other site
209261006377	structural Zn2+ binding site [ion binding]; other site
209261006378	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261006379	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261006380	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
209261006381	putative dimerization interface [polypeptide binding]; other site
209261006382	tricarballylate dehydrogenase; Validated; Region: PRK08274
209261006383	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
209261006384	tricarballylate utilization protein B; Provisional; Region: PRK15033
209261006385	citrate-proton symporter; Provisional; Region: PRK15075
209261006386	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261006387	putative substrate translocation pore; other site
209261006388	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
209261006389	YbfN-like lipoprotein; Region: YbfN; pfam13982
209261006390	outer membrane porin, OprD family; Region: OprD; pfam03573
209261006391	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
209261006392	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
209261006393	active site
209261006394	HIGH motif; other site
209261006395	nucleotide binding site [chemical binding]; other site
209261006396	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
209261006397	KMSKS motif; other site
209261006398	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
209261006399	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
209261006400	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
209261006401	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
209261006402	active site turn [active]
209261006403	phosphorylation site [posttranslational modification]
209261006404	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
209261006405	HPr interaction site; other site
209261006406	glycerol kinase (GK) interaction site [polypeptide binding]; other site
209261006407	active site
209261006408	phosphorylation site [posttranslational modification]
209261006409	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
209261006410	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
209261006411	active site
209261006412	trimer interface [polypeptide binding]; other site
209261006413	allosteric site; other site
209261006414	active site lid [active]
209261006415	hexamer (dimer of trimers) interface [polypeptide binding]; other site
209261006416	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
209261006417	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
209261006418	active site
209261006419	dimer interface [polypeptide binding]; other site
209261006420	MarR family; Region: MarR; pfam01047
209261006421	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
209261006422	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
209261006423	nucleotide binding site [chemical binding]; other site
209261006424	UMP phosphatase; Provisional; Region: PRK10444
209261006425	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261006426	active site
209261006427	motif I; other site
209261006428	motif II; other site
209261006429	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261006430	asparagine synthetase B; Provisional; Region: asnB; PRK09431
209261006431	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
209261006432	active site
209261006433	dimer interface [polypeptide binding]; other site
209261006434	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
209261006435	Ligand Binding Site [chemical binding]; other site
209261006436	Molecular Tunnel; other site
209261006437	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
209261006438	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
209261006439	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
209261006440	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
209261006441	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261006442	FeS/SAM binding site; other site
209261006443	TRAM domain; Region: TRAM; pfam01938
209261006444	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
209261006445	PhoH-like protein; Region: PhoH; pfam02562
209261006446	metal-binding heat shock protein; Provisional; Region: PRK00016
209261006447	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
209261006448	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
209261006449	Transporter associated domain; Region: CorC_HlyC; smart01091
209261006450	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
209261006451	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
209261006452	putative active site [active]
209261006453	catalytic triad [active]
209261006454	putative dimer interface [polypeptide binding]; other site
209261006455	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
209261006456	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261006457	substrate binding pocket [chemical binding]; other site
209261006458	membrane-bound complex binding site; other site
209261006459	hinge residues; other site
209261006460	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
209261006461	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261006462	dimer interface [polypeptide binding]; other site
209261006463	conserved gate region; other site
209261006464	putative PBP binding loops; other site
209261006465	ABC-ATPase subunit interface; other site
209261006466	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
209261006467	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261006468	dimer interface [polypeptide binding]; other site
209261006469	conserved gate region; other site
209261006470	putative PBP binding loops; other site
209261006471	ABC-ATPase subunit interface; other site
209261006472	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
209261006473	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
209261006474	Walker A/P-loop; other site
209261006475	ATP binding site [chemical binding]; other site
209261006476	Q-loop/lid; other site
209261006477	ABC transporter signature motif; other site
209261006478	Walker B; other site
209261006479	D-loop; other site
209261006480	H-loop/switch region; other site
209261006481	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
209261006482	active site
209261006483	tetramer interface [polypeptide binding]; other site
209261006484	hypothetical protein; Provisional; Region: PRK11032
209261006485	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
209261006486	Propionate catabolism activator; Region: PrpR_N; pfam06506
209261006487	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
209261006488	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261006489	Walker A motif; other site
209261006490	ATP binding site [chemical binding]; other site
209261006491	Walker B motif; other site
209261006492	arginine finger; other site
209261006493	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
209261006494	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
209261006495	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
209261006496	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
209261006497	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
209261006498	HIGH motif; other site
209261006499	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
209261006500	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
209261006501	active site
209261006502	KMSKS motif; other site
209261006503	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
209261006504	tRNA binding surface [nucleotide binding]; other site
209261006505	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
209261006506	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
209261006507	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
209261006508	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
209261006509	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
209261006510	active site
209261006511	(T/H)XGH motif; other site
209261006512	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
209261006513	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261006514	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261006515	homodimer interface [polypeptide binding]; other site
209261006516	catalytic residue [active]
209261006517	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
209261006518	catalytic core [active]
209261006519	ribosome-associated protein; Provisional; Region: PRK11538
209261006520	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
209261006521	penicillin-binding protein 2; Provisional; Region: PRK10795
209261006522	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
209261006523	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
209261006524	cell wall shape-determining protein; Provisional; Region: PRK10794
209261006525	rare lipoprotein A; Provisional; Region: PRK10672
209261006526	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
209261006527	Sporulation related domain; Region: SPOR; pfam05036
209261006528	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
209261006529	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
209261006530	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
209261006531	hypothetical protein; Provisional; Region: PRK04998
209261006532	lipoate-protein ligase B; Provisional; Region: PRK14342
209261006533	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
209261006534	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261006535	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
209261006536	substrate binding pocket [chemical binding]; other site
209261006537	dimerization interface [polypeptide binding]; other site
209261006538	lipoyl synthase; Provisional; Region: PRK05481
209261006539	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261006540	FeS/SAM binding site; other site
209261006541	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
209261006542	chromosome condensation membrane protein; Provisional; Region: PRK14196
209261006543	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
209261006544	DNA-binding site [nucleotide binding]; DNA binding site
209261006545	RNA-binding motif; other site
209261006546	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
209261006547	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
209261006548	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
209261006549	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
209261006550	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261006551	active site
209261006552	phosphorylation site [posttranslational modification]
209261006553	intermolecular recognition site; other site
209261006554	dimerization interface [polypeptide binding]; other site
209261006555	Transcriptional regulator; Region: CitT; pfam12431
209261006556	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
209261006557	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
209261006558	putative active site [active]
209261006559	heme pocket [chemical binding]; other site
209261006560	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261006561	ATP binding site [chemical binding]; other site
209261006562	Mg2+ binding site [ion binding]; other site
209261006563	G-X-G motif; other site
209261006564	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
209261006565	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
209261006566	putative active site [active]
209261006567	(T/H)XGH motif; other site
209261006568	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
209261006569	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
209261006570	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
209261006571	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
209261006572	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; cl01498
209261006573	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
209261006574	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
209261006575	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
209261006576	transmembrane helices; other site
209261006577	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
209261006578	B1 nucleotide binding pocket [chemical binding]; other site
209261006579	B2 nucleotide binding pocket [chemical binding]; other site
209261006580	CAS motifs; other site
209261006581	active site
209261006582	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
209261006583	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
209261006584	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
209261006585	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
209261006586	NAD binding site [chemical binding]; other site
209261006587	catalytic Zn binding site [ion binding]; other site
209261006588	structural Zn binding site [ion binding]; other site
209261006589	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
209261006590	Ligand Binding Site [chemical binding]; other site
209261006591	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
209261006592	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
209261006593	4Fe-4S binding domain; Region: Fer4; cl02805
209261006594	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
209261006595	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
209261006596	putative [4Fe-4S] binding site [ion binding]; other site
209261006597	putative molybdopterin cofactor binding site [chemical binding]; other site
209261006598	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
209261006599	molybdopterin cofactor binding site; other site
209261006600	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
209261006601	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261006602	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
209261006603	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
209261006604	catalytic residue [active]
209261006605	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
209261006606	catalytic residues [active]
209261006607	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
209261006608	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261006609	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
209261006610	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
209261006611	dimer interface [polypeptide binding]; other site
209261006612	decamer (pentamer of dimers) interface [polypeptide binding]; other site
209261006613	catalytic triad [active]
209261006614	peroxidatic and resolving cysteines [active]
209261006615	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
209261006616	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
209261006617	dimerization domain [polypeptide binding]; other site
209261006618	dimer interface [polypeptide binding]; other site
209261006619	catalytic residues [active]
209261006620	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
209261006621	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261006622	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
209261006623	dimerization interface [polypeptide binding]; other site
209261006624	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
209261006625	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
209261006626	Active Sites [active]
209261006627	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
209261006628	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
209261006629	ParB-like nuclease domain; Region: ParBc; pfam02195
209261006630	methionine aminotransferase; Validated; Region: PRK09082
209261006631	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261006632	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261006633	homodimer interface [polypeptide binding]; other site
209261006634	catalytic residue [active]
209261006635	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
209261006636	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
209261006637	putative active site [active]
209261006638	metal binding site [ion binding]; metal-binding site
209261006639	Uncharacterized small protein [Function unknown]; Region: COG2879
209261006640	carbon starvation protein A; Provisional; Region: PRK15015
209261006641	Carbon starvation protein CstA; Region: CstA; pfam02554
209261006642	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
209261006643	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
209261006644	CoenzymeA binding site [chemical binding]; other site
209261006645	subunit interaction site [polypeptide binding]; other site
209261006646	PHB binding site; other site
209261006647	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
209261006648	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
209261006649	putative NAD(P) binding site [chemical binding]; other site
209261006650	active site
209261006651	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
209261006652	hydrophobic substrate binding pocket; other site
209261006653	Isochorismatase family; Region: Isochorismatase; pfam00857
209261006654	active site
209261006655	conserved cis-peptide bond; other site
209261006656	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
209261006657	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
209261006658	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
209261006659	acyl-activating enzyme (AAE) consensus motif; other site
209261006660	active site
209261006661	AMP binding site [chemical binding]; other site
209261006662	substrate binding site [chemical binding]; other site
209261006663	isochorismate synthase EntC; Provisional; Region: PRK15016
209261006664	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
209261006665	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
209261006666	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
209261006667	siderophore binding site; other site
209261006668	enterobactin exporter EntS; Provisional; Region: PRK10489
209261006669	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261006670	putative substrate translocation pore; other site
209261006671	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
209261006672	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
209261006673	ABC-ATPase subunit  interface; other site
209261006674	dimer interface [polypeptide binding]; other site
209261006675	putative PBP binding regions; other site
209261006676	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
209261006677	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
209261006678	ABC-ATPase subunit  interface; other site
209261006679	dimer interface [polypeptide binding]; other site
209261006680	putative PBP binding regions; other site
209261006681	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
209261006682	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
209261006683	Walker A/P-loop; other site
209261006684	ATP binding site [chemical binding]; other site
209261006685	Q-loop/lid; other site
209261006686	ABC transporter signature motif; other site
209261006687	Walker B; other site
209261006688	D-loop; other site
209261006689	H-loop/switch region; other site
209261006690	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
209261006691	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
209261006692	acyl-activating enzyme (AAE) consensus motif; other site
209261006693	AMP binding site [chemical binding]; other site
209261006694	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
209261006695	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
209261006696	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
209261006697	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
209261006698	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
209261006699	outer membrane receptor FepA; Provisional; Region: PRK13524
209261006700	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
209261006701	N-terminal plug; other site
209261006702	ligand-binding site [chemical binding]; other site
209261006703	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
209261006704	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
209261006705	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
209261006706	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
209261006707	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
209261006708	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
209261006709	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261006710	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
209261006711	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261006712	hypothetical protein; Provisional; Region: PRK10250
209261006713	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
209261006714	dimer interface [polypeptide binding]; other site
209261006715	FMN binding site [chemical binding]; other site
209261006716	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
209261006717	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
209261006718	active site
209261006719	catalytic triad [active]
209261006720	oxyanion hole [active]
209261006721	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
209261006722	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
209261006723	Mechanosensitive ion channel; Region: MS_channel; pfam00924
209261006724	phenylalanine transporter; Provisional; Region: PRK10249
209261006725	Spore germination protein; Region: Spore_permease; cl17796
209261006726	Predicted membrane protein [Function unknown]; Region: COG3059
209261006727	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
209261006728	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
209261006729	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261006730	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
209261006731	Cupin; Region: Cupin_6; pfam12852
209261006732	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
209261006733	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261006734	Predicted membrane protein [Function unknown]; Region: COG2246
209261006735	GtrA-like protein; Region: GtrA; pfam04138
209261006736	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
209261006737	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
209261006738	Ligand binding site; other site
209261006739	Putative Catalytic site; other site
209261006740	DXD motif; other site
209261006741	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
209261006742	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261006743	DNA binding residues [nucleotide binding]
209261006744	dimerization interface [polypeptide binding]; other site
209261006745	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
209261006746	transcriptional regulator FimZ; Provisional; Region: PRK09935
209261006747	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261006748	active site
209261006749	phosphorylation site [posttranslational modification]
209261006750	intermolecular recognition site; other site
209261006751	dimerization interface [polypeptide binding]; other site
209261006752	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261006753	DNA binding residues [nucleotide binding]
209261006754	dimerization interface [polypeptide binding]; other site
209261006755	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
209261006756	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
209261006757	outer membrane usher protein FimD; Provisional; Region: PRK15198
209261006758	PapC N-terminal domain; Region: PapC_N; pfam13954
209261006759	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
209261006760	PapC C-terminal domain; Region: PapC_C; pfam13953
209261006761	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
209261006762	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261006763	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261006764	fimbrial protein FimI; Provisional; Region: PRK15200
209261006765	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
209261006766	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
209261006767	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
209261006768	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
209261006769	homodimer interface [polypeptide binding]; other site
209261006770	NADP binding site [chemical binding]; other site
209261006771	substrate binding site [chemical binding]; other site
209261006772	ribosome-associated protein; Provisional; Region: PRK11507
209261006773	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
209261006774	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
209261006775	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
209261006776	active site
209261006777	HIGH motif; other site
209261006778	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
209261006779	KMSKS motif; other site
209261006780	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
209261006781	tRNA binding surface [nucleotide binding]; other site
209261006782	anticodon binding site; other site
209261006783	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
209261006784	substrate binding site [chemical binding]; other site
209261006785	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
209261006786	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
209261006787	putative active site [active]
209261006788	putative metal binding site [ion binding]; other site
209261006789	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
209261006790	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
209261006791	ATP-grasp domain; Region: ATP-grasp; pfam02222
209261006792	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
209261006793	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
209261006794	putative substrate binding site [chemical binding]; other site
209261006795	nucleotide binding site [chemical binding]; other site
209261006796	nucleotide binding site [chemical binding]; other site
209261006797	homodimer interface [polypeptide binding]; other site
209261006798	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
209261006799	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
209261006800	membrane protein FdrA; Validated; Region: PRK06091
209261006801	CoA binding domain; Region: CoA_binding; pfam02629
209261006802	CoA-ligase; Region: Ligase_CoA; pfam00549
209261006803	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
209261006804	allantoate amidohydrolase; Region: AllC; TIGR03176
209261006805	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
209261006806	active site
209261006807	metal binding site [ion binding]; metal-binding site
209261006808	dimer interface [polypeptide binding]; other site
209261006809	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
209261006810	Mif2/CENP-C like; Region: Mif2; pfam11699
209261006811	Cupin domain; Region: Cupin_2; pfam07883
209261006812	glycerate kinase II; Provisional; Region: PRK09932
209261006813	putative uracil/xanthine transporter; Provisional; Region: PRK11412
209261006814	allantoinase; Provisional; Region: PRK08044
209261006815	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
209261006816	active site
209261006817	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261006818	Major Facilitator Superfamily; Region: MFS_1; pfam07690
209261006819	putative substrate translocation pore; other site
209261006820	tartronate semialdehyde reductase; Provisional; Region: PRK15059
209261006821	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
209261006822	hydroxypyruvate isomerase; Provisional; Region: PRK09997
209261006823	glyoxylate carboligase; Provisional; Region: PRK11269
209261006824	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
209261006825	PYR/PP interface [polypeptide binding]; other site
209261006826	dimer interface [polypeptide binding]; other site
209261006827	TPP binding site [chemical binding]; other site
209261006828	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
209261006829	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
209261006830	TPP-binding site [chemical binding]; other site
209261006831	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
209261006832	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
209261006833	Bacterial transcriptional regulator; Region: IclR; pfam01614
209261006834	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
209261006835	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261006836	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
209261006837	dimerization interface [polypeptide binding]; other site
209261006838	Predicted ATPase [General function prediction only]; Region: COG2603
209261006839	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
209261006840	active site residue [active]
209261006841	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261006842	dimer interface [polypeptide binding]; other site
209261006843	conserved gate region; other site
209261006844	ABC-ATPase subunit interface; other site
209261006845	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
209261006846	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
209261006847	Walker A/P-loop; other site
209261006848	ATP binding site [chemical binding]; other site
209261006849	Q-loop/lid; other site
209261006850	ABC transporter signature motif; other site
209261006851	Walker B; other site
209261006852	D-loop; other site
209261006853	H-loop/switch region; other site
209261006854	NIL domain; Region: NIL; pfam09383
209261006855	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
209261006856	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
209261006857	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
209261006858	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
209261006859	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
209261006860	FtsX-like permease family; Region: FtsX; pfam02687
209261006861	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
209261006862	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
209261006863	Walker A/P-loop; other site
209261006864	ATP binding site [chemical binding]; other site
209261006865	Q-loop/lid; other site
209261006866	ABC transporter signature motif; other site
209261006867	Walker B; other site
209261006868	D-loop; other site
209261006869	H-loop/switch region; other site
209261006870	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
209261006871	active site
209261006872	catalytic triad [active]
209261006873	oxyanion hole [active]
209261006874	switch loop; other site
209261006875	oxidoreductase; Provisional; Region: PRK08017
209261006876	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
209261006877	NADP binding site [chemical binding]; other site
209261006878	active site
209261006879	steroid binding site; other site
209261006880	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
209261006881	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
209261006882	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
209261006883	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
209261006884	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
209261006885	Walker A/P-loop; other site
209261006886	ATP binding site [chemical binding]; other site
209261006887	Q-loop/lid; other site
209261006888	ABC transporter signature motif; other site
209261006889	Walker B; other site
209261006890	D-loop; other site
209261006891	H-loop/switch region; other site
209261006892	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
209261006893	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
209261006894	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
209261006895	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
209261006896	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
209261006897	DNA binding residues [nucleotide binding]
209261006898	dimer interface [polypeptide binding]; other site
209261006899	copper binding site [ion binding]; other site
209261006900	copper exporting ATPase; Provisional; Region: copA; PRK10671
209261006901	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
209261006902	metal-binding site [ion binding]
209261006903	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
209261006904	metal-binding site [ion binding]
209261006905	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
209261006906	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261006907	motif II; other site
209261006908	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
209261006909	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
209261006910	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
209261006911	putative deacylase active site [active]
209261006912	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261006913	Major Facilitator Superfamily; Region: MFS_1; pfam07690
209261006914	putative substrate translocation pore; other site
209261006915	putative cation:proton antiport protein; Provisional; Region: PRK10669
209261006916	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
209261006917	TrkA-N domain; Region: TrkA_N; pfam02254
209261006918	inosine/guanosine kinase; Provisional; Region: PRK15074
209261006919	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
209261006920	acetyl esterase; Provisional; Region: PRK10162
209261006921	ferrochelatase; Reviewed; Region: hemH; PRK00035
209261006922	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
209261006923	C-terminal domain interface [polypeptide binding]; other site
209261006924	active site
209261006925	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
209261006926	active site
209261006927	N-terminal domain interface [polypeptide binding]; other site
209261006928	adenylate kinase; Reviewed; Region: adk; PRK00279
209261006929	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
209261006930	AMP-binding site [chemical binding]; other site
209261006931	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
209261006932	heat shock protein 90; Provisional; Region: PRK05218
209261006933	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261006934	ATP binding site [chemical binding]; other site
209261006935	Mg2+ binding site [ion binding]; other site
209261006936	G-X-G motif; other site
209261006937	recombination protein RecR; Reviewed; Region: recR; PRK00076
209261006938	RecR protein; Region: RecR; pfam02132
209261006939	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
209261006940	putative active site [active]
209261006941	putative metal-binding site [ion binding]; other site
209261006942	tetramer interface [polypeptide binding]; other site
209261006943	hypothetical protein; Validated; Region: PRK00153
209261006944	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
209261006945	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261006946	Walker A motif; other site
209261006947	ATP binding site [chemical binding]; other site
209261006948	Walker B motif; other site
209261006949	DNA polymerase III subunit delta'; Validated; Region: PRK08485
209261006950	arginine finger; other site
209261006951	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
209261006952	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
209261006953	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
209261006954	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
209261006955	active site
209261006956	hypothetical protein; Provisional; Region: PRK10527
209261006957	hypothetical protein; Provisional; Region: PRK11038
209261006958	Uncharacterized conserved protein [Function unknown]; Region: COG5464
209261006959	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
209261006960	hypothetical protein; Provisional; Region: PRK11281
209261006961	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
209261006962	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
209261006963	Mechanosensitive ion channel; Region: MS_channel; pfam00924
209261006964	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
209261006965	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261006966	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
209261006967	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
209261006968	HlyD family secretion protein; Region: HlyD_3; pfam13437
209261006969	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
209261006970	Protein export membrane protein; Region: SecD_SecF; cl14618
209261006971	Protein export membrane protein; Region: SecD_SecF; cl14618
209261006972	Hha toxicity attenuator; Provisional; Region: PRK10667
209261006973	gene expression modulator; Provisional; Region: PRK10945
209261006974	maltose O-acetyltransferase; Provisional; Region: PRK10092
209261006975	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
209261006976	active site
209261006977	substrate binding site [chemical binding]; other site
209261006978	trimer interface [polypeptide binding]; other site
209261006979	CoA binding site [chemical binding]; other site
209261006980	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
209261006981	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
209261006982	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
209261006983	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
209261006984	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
209261006985	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261006986	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
209261006987	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
209261006988	DNA binding site [nucleotide binding]
209261006989	active site
209261006990	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
209261006991	acyl-CoA thioesterase II; Provisional; Region: PRK10526
209261006992	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
209261006993	active site
209261006994	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
209261006995	catalytic triad [active]
209261006996	dimer interface [polypeptide binding]; other site
209261006997	ammonium transporter; Provisional; Region: PRK10666
209261006998	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
209261006999	Nitrogen regulatory protein P-II; Region: P-II; smart00938
209261007000	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
209261007001	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
209261007002	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261007003	Walker A/P-loop; other site
209261007004	ATP binding site [chemical binding]; other site
209261007005	Q-loop/lid; other site
209261007006	ABC transporter signature motif; other site
209261007007	Walker B; other site
209261007008	D-loop; other site
209261007009	H-loop/switch region; other site
209261007010	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
209261007011	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
209261007012	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261007013	Walker A/P-loop; other site
209261007014	ATP binding site [chemical binding]; other site
209261007015	Q-loop/lid; other site
209261007016	ABC transporter signature motif; other site
209261007017	Walker B; other site
209261007018	D-loop; other site
209261007019	H-loop/switch region; other site
209261007020	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
209261007021	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
209261007022	putative DNA binding site [nucleotide binding]; other site
209261007023	putative Zn2+ binding site [ion binding]; other site
209261007024	AsnC family; Region: AsnC_trans_reg; pfam01037
209261007025	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
209261007026	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
209261007027	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
209261007028	catalytic residue [active]
209261007029	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261007030	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
209261007031	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261007032	active site
209261007033	motif I; other site
209261007034	motif II; other site
209261007035	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
209261007036	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
209261007037	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
209261007038	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
209261007039	Ligand Binding Site [chemical binding]; other site
209261007040	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
209261007041	active site
209261007042	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
209261007043	periplasmic folding chaperone; Provisional; Region: PRK10788
209261007044	SurA N-terminal domain; Region: SurA_N_3; cl07813
209261007045	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
209261007046	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
209261007047	IHF dimer interface [polypeptide binding]; other site
209261007048	IHF - DNA interface [nucleotide binding]; other site
209261007049	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
209261007050	Found in ATP-dependent protease La (LON); Region: LON; smart00464
209261007051	Found in ATP-dependent protease La (LON); Region: LON; smart00464
209261007052	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261007053	Walker A motif; other site
209261007054	ATP binding site [chemical binding]; other site
209261007055	Walker B motif; other site
209261007056	arginine finger; other site
209261007057	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
209261007058	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
209261007059	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
209261007060	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261007061	Walker A motif; other site
209261007062	ATP binding site [chemical binding]; other site
209261007063	Walker B motif; other site
209261007064	Iron permease FTR1 family; Region: FTR1; cl00475
209261007065	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
209261007066	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
209261007067	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
209261007068	oligomer interface [polypeptide binding]; other site
209261007069	active site residues [active]
209261007070	trigger factor; Provisional; Region: tig; PRK01490
209261007071	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
209261007072	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
209261007073	transcriptional regulator BolA; Provisional; Region: PRK11628
209261007074	hypothetical protein; Provisional; Region: PRK11627
209261007075	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
209261007076	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
209261007077	muropeptide transporter; Reviewed; Region: ampG; PRK11902
209261007078	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261007079	putative substrate translocation pore; other site
209261007080	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
209261007081	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
209261007082	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
209261007083	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
209261007084	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
209261007085	D-pathway; other site
209261007086	Putative ubiquinol binding site [chemical binding]; other site
209261007087	Low-spin heme (heme b) binding site [chemical binding]; other site
209261007088	Putative water exit pathway; other site
209261007089	Binuclear center (heme o3/CuB) [ion binding]; other site
209261007090	K-pathway; other site
209261007091	Putative proton exit pathway; other site
209261007092	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
209261007093	Subunit I/III interface [polypeptide binding]; other site
209261007094	Subunit III/IV interface [polypeptide binding]; other site
209261007095	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
209261007096	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
209261007097	UbiA prenyltransferase family; Region: UbiA; pfam01040
209261007098	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
209261007099	Sel1-like repeats; Region: SEL1; smart00671
209261007100	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
209261007101	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
209261007102	Sel1-like repeats; Region: SEL1; smart00671
209261007103	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
209261007104	Sel1 repeat; Region: Sel1; pfam08238
209261007105	Sel1-like repeats; Region: SEL1; smart00671
209261007106	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
209261007107	Sel1-like repeats; Region: SEL1; smart00671
209261007108	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261007109	Major Facilitator Superfamily; Region: MFS_1; pfam07690
209261007110	putative substrate translocation pore; other site
209261007111	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
209261007112	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
209261007113	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
209261007114	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
209261007115	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
209261007116	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
209261007117	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
209261007118	conserved cys residue [active]
209261007119	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
209261007120	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261007121	motif II; other site
209261007122	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
209261007123	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
209261007124	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
209261007125	catalytic residue [active]
209261007126	transcriptional regulator protein; Region: phnR; TIGR03337
209261007127	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261007128	DNA-binding site [nucleotide binding]; DNA binding site
209261007129	UTRA domain; Region: UTRA; pfam07702
209261007130	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
209261007131	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
209261007132	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
209261007133	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261007134	Walker A/P-loop; other site
209261007135	ATP binding site [chemical binding]; other site
209261007136	Q-loop/lid; other site
209261007137	ABC transporter signature motif; other site
209261007138	Walker B; other site
209261007139	D-loop; other site
209261007140	H-loop/switch region; other site
209261007141	TOBE domain; Region: TOBE_2; pfam08402
209261007142	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
209261007143	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261007144	dimer interface [polypeptide binding]; other site
209261007145	conserved gate region; other site
209261007146	putative PBP binding loops; other site
209261007147	ABC-ATPase subunit interface; other site
209261007148	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
209261007149	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261007150	dimer interface [polypeptide binding]; other site
209261007151	conserved gate region; other site
209261007152	putative PBP binding loops; other site
209261007153	ABC-ATPase subunit interface; other site
209261007154	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
209261007155	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
209261007156	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
209261007157	Ligand Binding Site [chemical binding]; other site
209261007158	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
209261007159	active site residue [active]
209261007160	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
209261007161	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
209261007162	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
209261007163	substrate binding pocket [chemical binding]; other site
209261007164	chain length determination region; other site
209261007165	substrate-Mg2+ binding site; other site
209261007166	catalytic residues [active]
209261007167	aspartate-rich region 1; other site
209261007168	active site lid residues [active]
209261007169	aspartate-rich region 2; other site
209261007170	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
209261007171	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
209261007172	TPP-binding site; other site
209261007173	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
209261007174	PYR/PP interface [polypeptide binding]; other site
209261007175	dimer interface [polypeptide binding]; other site
209261007176	TPP binding site [chemical binding]; other site
209261007177	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
209261007178	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
209261007179	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
209261007180	active site
209261007181	catalytic tetrad [active]
209261007182	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
209261007183	tetramer interfaces [polypeptide binding]; other site
209261007184	binuclear metal-binding site [ion binding]; other site
209261007185	thiamine monophosphate kinase; Provisional; Region: PRK05731
209261007186	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
209261007187	ATP binding site [chemical binding]; other site
209261007188	dimerization interface [polypeptide binding]; other site
209261007189	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
209261007190	putative RNA binding site [nucleotide binding]; other site
209261007191	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
209261007192	homopentamer interface [polypeptide binding]; other site
209261007193	active site
209261007194	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
209261007195	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
209261007196	catalytic motif [active]
209261007197	Zn binding site [ion binding]; other site
209261007198	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
209261007199	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
209261007200	ATP cone domain; Region: ATP-cone; pfam03477
209261007201	hypothetical protein; Provisional; Region: PRK11530
209261007202	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
209261007203	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
209261007204	active site
209261007205	Predicted transcriptional regulator [Transcription]; Region: COG2378
209261007206	HTH domain; Region: HTH_11; pfam08279
209261007207	WYL domain; Region: WYL; pfam13280
209261007208	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
209261007209	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
209261007210	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
209261007211	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
209261007212	Protein export membrane protein; Region: SecD_SecF; pfam02355
209261007213	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
209261007214	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
209261007215	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
209261007216	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
209261007217	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
209261007218	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
209261007219	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
209261007220	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
209261007221	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
209261007222	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
209261007223	peroxidase; Provisional; Region: PRK15000
209261007224	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
209261007225	dimer interface [polypeptide binding]; other site
209261007226	decamer (pentamer of dimers) interface [polypeptide binding]; other site
209261007227	catalytic triad [active]
209261007228	peroxidatic and resolving cysteines [active]
209261007229	maltodextrin glucosidase; Provisional; Region: PRK10785
209261007230	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
209261007231	homodimer interface [polypeptide binding]; other site
209261007232	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
209261007233	active site
209261007234	homodimer interface [polypeptide binding]; other site
209261007235	catalytic site [active]
209261007236	putative proline-specific permease; Provisional; Region: proY; PRK10580
209261007237	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261007238	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
209261007239	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
209261007240	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
209261007241	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
209261007242	putative active site [active]
209261007243	heme pocket [chemical binding]; other site
209261007244	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261007245	dimer interface [polypeptide binding]; other site
209261007246	phosphorylation site [posttranslational modification]
209261007247	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261007248	ATP binding site [chemical binding]; other site
209261007249	Mg2+ binding site [ion binding]; other site
209261007250	G-X-G motif; other site
209261007251	transcriptional regulator PhoB; Provisional; Region: PRK10161
209261007252	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261007253	active site
209261007254	phosphorylation site [posttranslational modification]
209261007255	intermolecular recognition site; other site
209261007256	dimerization interface [polypeptide binding]; other site
209261007257	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261007258	DNA binding site [nucleotide binding]
209261007259	exonuclease subunit SbcD; Provisional; Region: PRK10966
209261007260	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
209261007261	active site
209261007262	metal binding site [ion binding]; metal-binding site
209261007263	DNA binding site [nucleotide binding]
209261007264	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
209261007265	exonuclease subunit SbcC; Provisional; Region: PRK10246
209261007266	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261007267	Walker A/P-loop; other site
209261007268	ATP binding site [chemical binding]; other site
209261007269	Q-loop/lid; other site
209261007270	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261007271	ABC transporter signature motif; other site
209261007272	Walker B; other site
209261007273	D-loop; other site
209261007274	H-loop/switch region; other site
209261007275	fructokinase; Reviewed; Region: PRK09557
209261007276	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
209261007277	nucleotide binding site [chemical binding]; other site
209261007278	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
209261007279	hypothetical protein; Provisional; Region: PRK10579
209261007280	hypothetical protein; Provisional; Region: PRK10380
209261007281	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
209261007282	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
209261007283	ADP binding site [chemical binding]; other site
209261007284	magnesium binding site [ion binding]; other site
209261007285	putative shikimate binding site; other site
209261007286	hypothetical protein; Validated; Region: PRK00124
209261007287	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
209261007288	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
209261007289	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
209261007290	MASE2 domain; Region: MASE2; pfam05230
209261007291	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
209261007292	metal binding site [ion binding]; metal-binding site
209261007293	active site
209261007294	I-site; other site
209261007295	hypothetical protein; Provisional; Region: PRK11505
209261007296	psiF repeat; Region: PsiF_repeat; pfam07769
209261007297	psiF repeat; Region: PsiF_repeat; pfam07769
209261007298	anti-RssB factor; Provisional; Region: PRK10244
209261007299	drug efflux system protein MdtG; Provisional; Region: PRK09874
209261007300	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261007301	putative substrate translocation pore; other site
209261007302	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
209261007303	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
209261007304	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
209261007305	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
209261007306	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
209261007307	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
209261007308	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
209261007309	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
209261007310	microcin B17 transporter; Reviewed; Region: PRK11098
209261007311	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
209261007312	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
209261007313	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
209261007314	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
209261007315	ligand binding site [chemical binding]; other site
209261007316	flexible hinge region; other site
209261007317	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
209261007318	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
209261007319	Autotransporter beta-domain; Region: Autotransporter; pfam03797
209261007320	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
209261007321	dimer interface [polypeptide binding]; other site
209261007322	active site
209261007323	Schiff base residues; other site
209261007324	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
209261007325	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
209261007326	acyl-activating enzyme (AAE) consensus motif; other site
209261007327	AMP binding site [chemical binding]; other site
209261007328	active site
209261007329	CoA binding site [chemical binding]; other site
209261007330	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
209261007331	2-methylcitrate dehydratase; Region: prpD; TIGR02330
209261007332	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
209261007333	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
209261007334	dimer interface [polypeptide binding]; other site
209261007335	active site
209261007336	citrylCoA binding site [chemical binding]; other site
209261007337	oxalacetate/citrate binding site [chemical binding]; other site
209261007338	coenzyme A binding site [chemical binding]; other site
209261007339	catalytic triad [active]
209261007340	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
209261007341	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
209261007342	tetramer interface [polypeptide binding]; other site
209261007343	active site
209261007344	Mg2+/Mn2+ binding site [ion binding]; other site
209261007345	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
209261007346	Propionate catabolism activator; Region: PrpR_N; pfam06506
209261007347	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261007348	Walker A motif; other site
209261007349	ATP binding site [chemical binding]; other site
209261007350	Walker B motif; other site
209261007351	arginine finger; other site
209261007352	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
209261007353	hypothetical protein; Provisional; Region: PRK09929
209261007354	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
209261007355	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
209261007356	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
209261007357	N-terminal plug; other site
209261007358	ligand-binding site [chemical binding]; other site
209261007359	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
209261007360	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
209261007361	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
209261007362	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
209261007363	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
209261007364	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
209261007365	DNA methylase; Region: N6_N4_Mtase; cl17433
209261007366	DNA methylase; Region: N6_N4_Mtase; pfam01555
209261007367	putative sialic acid transporter; Region: 2A0112; TIGR00891
209261007368	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261007369	putative substrate translocation pore; other site
209261007370	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
209261007371	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
209261007372	DNA binding residues [nucleotide binding]
209261007373	dimerization interface [polypeptide binding]; other site
209261007374	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
209261007375	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
209261007376	DNA binding site [nucleotide binding]
209261007377	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
209261007378	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261007379	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
209261007380	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
209261007381	fimbrial chaperone protein StbB; Provisional; Region: PRK15249
209261007382	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261007383	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261007384	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
209261007385	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
209261007386	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261007387	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261007388	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
209261007389	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
209261007390	putative catalytic cysteine [active]
209261007391	gamma-glutamyl kinase; Provisional; Region: PRK05429
209261007392	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
209261007393	nucleotide binding site [chemical binding]; other site
209261007394	homotetrameric interface [polypeptide binding]; other site
209261007395	putative phosphate binding site [ion binding]; other site
209261007396	putative allosteric binding site; other site
209261007397	PUA domain; Region: PUA; pfam01472
209261007398	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
209261007399	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
209261007400	trimer interface [polypeptide binding]; other site
209261007401	eyelet of channel; other site
209261007402	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
209261007403	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
209261007404	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
209261007405	active site
209261007406	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
209261007407	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
209261007408	metal binding site [ion binding]; metal-binding site
209261007409	dimer interface [polypeptide binding]; other site
209261007410	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
209261007411	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
209261007412	hypothetical protein; Reviewed; Region: PRK09588
209261007413	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
209261007414	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
209261007415	active site
209261007416	DNA polymerase IV; Validated; Region: PRK02406
209261007417	DNA binding site [nucleotide binding]
209261007418	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
209261007419	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
209261007420	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
209261007421	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
209261007422	putative active site [active]
209261007423	putative dimer interface [polypeptide binding]; other site
209261007424	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
209261007425	dimer interface [polypeptide binding]; other site
209261007426	active site
209261007427	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
209261007428	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
209261007429	active site
209261007430	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
209261007431	C-N hydrolase family amidase; Provisional; Region: PRK10438
209261007432	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
209261007433	putative active site [active]
209261007434	catalytic triad [active]
209261007435	dimer interface [polypeptide binding]; other site
209261007436	multimer interface [polypeptide binding]; other site
209261007437	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
209261007438	dimer interface [polypeptide binding]; other site
209261007439	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
209261007440	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
209261007441	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
209261007442	AsnC family; Region: AsnC_trans_reg; pfam01037
209261007443	putative fimbrial protein TcfD; Provisional; Region: PRK15311
209261007444	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
209261007445	putative fimbrial subunit TcfB; Provisional; Region: PRK15309
209261007446	putative fimbrial protein TcfA; Provisional; Region: PRK15308
209261007447	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
209261007448	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261007449	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261007450	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
209261007451	dimerization interface [polypeptide binding]; other site
209261007452	PerC transcriptional activator; Region: PerC; pfam06069
209261007453	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
209261007454	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
209261007455	putative active site [active]
209261007456	putative metal binding site [ion binding]; other site
209261007457	putative pilin structural protein SafD; Provisional; Region: PRK15222
209261007458	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
209261007459	PapC N-terminal domain; Region: PapC_N; pfam13954
209261007460	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
209261007461	PapC C-terminal domain; Region: PapC_C; pfam13953
209261007462	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
209261007463	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261007464	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261007465	Saf-pilin pilus formation protein SafA; Provisional; Region: PRK15221
209261007466	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
209261007467	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
209261007468	The BURPS668_1122 family of deaminases; Region: Toxin-deaminase; pfam14424
209261007469	RHS Repeat; Region: RHS_repeat; cl11982
209261007470	RHS Repeat; Region: RHS_repeat; pfam05593
209261007471	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
209261007472	RHS Repeat; Region: RHS_repeat; pfam05593
209261007473	RHS Repeat; Region: RHS_repeat; pfam05593
209261007474	RHS Repeat; Region: RHS_repeat; pfam05593
209261007475	RHS Repeat; Region: RHS_repeat; pfam05593
209261007476	RHS protein; Region: RHS; pfam03527
209261007477	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
209261007478	PAAR motif; Region: PAAR_motif; pfam05488
209261007479	RHS Repeat; Region: RHS_repeat; cl11982
209261007480	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
209261007481	RHS Repeat; Region: RHS_repeat; pfam05593
209261007482	RHS Repeat; Region: RHS_repeat; pfam05593
209261007483	RHS protein; Region: RHS; pfam03527
209261007484	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
209261007485	A nuclease family of the HNH/ENDO VII superfamily with conserved AHH; Region: AHH; pfam14412
209261007486	Uncharacterized conserved protein [Function unknown]; Region: COG5435
209261007487	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501
209261007488	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
209261007489	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
209261007490	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4893
209261007491	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
209261007492	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; cl01611
209261007493	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
209261007494	hypothetical protein; Provisional; Region: PRK08126
209261007495	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
209261007496	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
209261007497	ligand binding site [chemical binding]; other site
209261007498	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
209261007499	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
209261007500	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
209261007501	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
209261007502	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
209261007503	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
209261007504	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261007505	Walker A motif; other site
209261007506	ATP binding site [chemical binding]; other site
209261007507	Walker B motif; other site
209261007508	arginine finger; other site
209261007509	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261007510	Walker A motif; other site
209261007511	ATP binding site [chemical binding]; other site
209261007512	Walker B motif; other site
209261007513	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
209261007514	similar to hypothetical protein; corresponds to STY0293 from Accession AL513382: Salmonella typhi CT18
209261007515	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
209261007516	ImpE protein; Region: ImpE; pfam07024
209261007517	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
209261007518	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
209261007519	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
209261007520	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
209261007521	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
209261007522	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
209261007523	active site
209261007524	catalytic site [active]
209261007525	substrate binding site [chemical binding]; other site
209261007526	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
209261007527	RNA/DNA hybrid binding site [nucleotide binding]; other site
209261007528	active site
209261007529	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261007530	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
209261007531	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
209261007532	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
209261007533	N-acetyl-D-glucosamine binding site [chemical binding]; other site
209261007534	catalytic residue [active]
209261007535	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
209261007536	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
209261007537	Methyltransferase domain; Region: Methyltransf_23; pfam13489
209261007538	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261007539	S-adenosylmethionine binding site [chemical binding]; other site
209261007540	hypothetical protein; Provisional; Region: PRK05421
209261007541	putative catalytic site [active]
209261007542	putative metal binding site [ion binding]; other site
209261007543	putative phosphate binding site [ion binding]; other site
209261007544	putative catalytic site [active]
209261007545	putative phosphate binding site [ion binding]; other site
209261007546	putative metal binding site [ion binding]; other site
209261007547	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
209261007548	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261007549	putative substrate translocation pore; other site
209261007550	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261007551	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261007552	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
209261007553	putative effector binding pocket; other site
209261007554	dimerization interface [polypeptide binding]; other site
209261007555	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
209261007556	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
209261007557	active site
209261007558	catalytic tetrad [active]
209261007559	protein disaggregation chaperone; Provisional; Region: PRK10865
209261007560	Clp amino terminal domain; Region: Clp_N; pfam02861
209261007561	Clp amino terminal domain; Region: Clp_N; pfam02861
209261007562	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261007563	Walker A motif; other site
209261007564	ATP binding site [chemical binding]; other site
209261007565	Walker B motif; other site
209261007566	arginine finger; other site
209261007567	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261007568	Walker A motif; other site
209261007569	ATP binding site [chemical binding]; other site
209261007570	Walker B motif; other site
209261007571	arginine finger; other site
209261007572	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
209261007573	hypothetical protein; Provisional; Region: PRK10723
209261007574	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
209261007575	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
209261007576	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
209261007577	RNA binding surface [nucleotide binding]; other site
209261007578	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
209261007579	active site
209261007580	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
209261007581	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
209261007582	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
209261007583	30S subunit binding site; other site
209261007584	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
209261007585	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
209261007586	Prephenate dehydratase; Region: PDT; pfam00800
209261007587	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
209261007588	putative L-Phe binding site [chemical binding]; other site
209261007589	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
209261007590	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
209261007591	Chorismate mutase type II; Region: CM_2; cl00693
209261007592	prephenate dehydrogenase; Validated; Region: PRK08507
209261007593	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
209261007594	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
209261007595	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
209261007596	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
209261007597	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
209261007598	metal binding site [ion binding]; metal-binding site
209261007599	active site
209261007600	I-site; other site
209261007601	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
209261007602	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
209261007603	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
209261007604	RimM N-terminal domain; Region: RimM; pfam01782
209261007605	PRC-barrel domain; Region: PRC; pfam05239
209261007606	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
209261007607	signal recognition particle protein; Provisional; Region: PRK10867
209261007608	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
209261007609	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
209261007610	P loop; other site
209261007611	GTP binding site [chemical binding]; other site
209261007612	Signal peptide binding domain; Region: SRP_SPB; pfam02978
209261007613	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
209261007614	hypothetical protein; Provisional; Region: PRK11573
209261007615	Domain of unknown function DUF21; Region: DUF21; pfam01595
209261007616	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
209261007617	Transporter associated domain; Region: CorC_HlyC; smart01091
209261007618	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
209261007619	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
209261007620	dimer interface [polypeptide binding]; other site
209261007621	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
209261007622	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
209261007623	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
209261007624	recombination and repair protein; Provisional; Region: PRK10869
209261007625	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
209261007626	Walker A/P-loop; other site
209261007627	ATP binding site [chemical binding]; other site
209261007628	Q-loop/lid; other site
209261007629	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
209261007630	ABC transporter signature motif; other site
209261007631	Walker B; other site
209261007632	D-loop; other site
209261007633	H-loop/switch region; other site
209261007634	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
209261007635	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
209261007636	hypothetical protein; Validated; Region: PRK01777
209261007637	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
209261007638	putative coenzyme Q binding site [chemical binding]; other site
209261007639	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
209261007640	SmpB-tmRNA interface; other site
209261007641	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261007642	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261007643	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261007644	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261007645	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261007646	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261007647	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
209261007648	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261007649	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261007650	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
209261007651	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261007652	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261007653	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
209261007654	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
209261007655	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
209261007656	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
209261007657	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261007658	Walker A/P-loop; other site
209261007659	ATP binding site [chemical binding]; other site
209261007660	Q-loop/lid; other site
209261007661	ABC transporter signature motif; other site
209261007662	Walker B; other site
209261007663	D-loop; other site
209261007664	H-loop/switch region; other site
209261007665	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
209261007666	HlyD family secretion protein; Region: HlyD_3; pfam13437
209261007667	integrase; Provisional; Region: PRK09692
209261007668	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
209261007669	active site
209261007670	Int/Topo IB signature motif; other site
209261007671	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
209261007672	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
209261007673	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
209261007674	Ash protein family; Region: Phage_ASH; pfam10554
209261007675	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
209261007676	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
209261007677	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
209261007678	active site
209261007679	metal binding site [ion binding]; metal-binding site
209261007680	interdomain interaction site; other site
209261007681	D5 N terminal like; Region: D5_N; smart00885
209261007682	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
209261007683	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
209261007684	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
209261007685	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
209261007686	putative active site [active]
209261007687	putative NTP binding site [chemical binding]; other site
209261007688	putative nucleic acid binding site [nucleotide binding]; other site
209261007689	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
209261007690	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
209261007691	tail protein; Provisional; Region: D; PHA02561
209261007692	Phage protein U [General function prediction only]; Region: COG3499
209261007693	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
209261007694	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
209261007695	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
209261007696	major tail tube protein; Provisional; Region: FII; PHA02600
209261007697	major tail sheath protein; Provisional; Region: FI; PHA02560
209261007698	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
209261007699	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
209261007700	catalytic residues [active]
209261007701	catalytic nucleophile [active]
209261007702	Presynaptic Site I dimer interface [polypeptide binding]; other site
209261007703	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
209261007704	Synaptic Flat tetramer interface [polypeptide binding]; other site
209261007705	Synaptic Site I dimer interface [polypeptide binding]; other site
209261007706	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
209261007707	DNA-binding interface [nucleotide binding]; DNA binding site
209261007708	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
209261007709	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
209261007710	homodimer interface [polypeptide binding]; other site
209261007711	active site
209261007712	TDP-binding site; other site
209261007713	acceptor substrate-binding pocket; other site
209261007714	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
209261007715	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261007716	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
209261007717	Walker A/P-loop; other site
209261007718	ATP binding site [chemical binding]; other site
209261007719	Q-loop/lid; other site
209261007720	ABC transporter signature motif; other site
209261007721	Walker B; other site
209261007722	D-loop; other site
209261007723	H-loop/switch region; other site
209261007724	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
209261007725	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
209261007726	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261007727	Walker A/P-loop; other site
209261007728	ATP binding site [chemical binding]; other site
209261007729	Q-loop/lid; other site
209261007730	ABC transporter signature motif; other site
209261007731	Walker B; other site
209261007732	D-loop; other site
209261007733	H-loop/switch region; other site
209261007734	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
209261007735	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
209261007736	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
209261007737	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
209261007738	outer membrane receptor FepA; Provisional; Region: PRK13528
209261007739	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
209261007740	N-terminal plug; other site
209261007741	ligand-binding site [chemical binding]; other site
209261007742	secreted effector protein PipB2; Provisional; Region: PRK15196
209261007743	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
209261007744	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
209261007745	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
209261007746	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
209261007747	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
209261007748	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
209261007749	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
209261007750	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
209261007751	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
209261007752	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
209261007753	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
209261007754	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261007755	dimer interface [polypeptide binding]; other site
209261007756	phosphorylation site [posttranslational modification]
209261007757	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261007758	ATP binding site [chemical binding]; other site
209261007759	Mg2+ binding site [ion binding]; other site
209261007760	G-X-G motif; other site
209261007761	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
209261007762	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261007763	active site
209261007764	phosphorylation site [posttranslational modification]
209261007765	intermolecular recognition site; other site
209261007766	dimerization interface [polypeptide binding]; other site
209261007767	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261007768	DNA binding site [nucleotide binding]
209261007769	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
209261007770	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
209261007771	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
209261007772	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
209261007773	substrate binding pocket [chemical binding]; other site
209261007774	active site
209261007775	iron coordination sites [ion binding]; other site
209261007776	Predicted dehydrogenase [General function prediction only]; Region: COG0579
209261007777	hydroxyglutarate oxidase; Provisional; Region: PRK11728
209261007778	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
209261007779	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
209261007780	tetramerization interface [polypeptide binding]; other site
209261007781	NAD(P) binding site [chemical binding]; other site
209261007782	catalytic residues [active]
209261007783	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
209261007784	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
209261007785	inhibitor-cofactor binding pocket; inhibition site
209261007786	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261007787	catalytic residue [active]
209261007788	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
209261007789	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261007790	DNA-binding site [nucleotide binding]; DNA binding site
209261007791	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
209261007792	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
209261007793	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
209261007794	dimerization interface [polypeptide binding]; other site
209261007795	putative DNA binding site [nucleotide binding]; other site
209261007796	putative Zn2+ binding site [ion binding]; other site
209261007797	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
209261007798	active site residue [active]
209261007799	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
209261007800	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
209261007801	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
209261007802	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
209261007803	hypothetical protein; Provisional; Region: PRK10556
209261007804	hypothetical protein; Provisional; Region: PRK10132
209261007805	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
209261007806	Uncharacterized conserved protein [Function unknown]; Region: COG2128
209261007807	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
209261007808	catalytic residues [active]
209261007809	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
209261007810	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
209261007811	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
209261007812	Class I ribonucleotide reductase; Region: RNR_I; cd01679
209261007813	active site
209261007814	dimer interface [polypeptide binding]; other site
209261007815	catalytic residues [active]
209261007816	effector binding site; other site
209261007817	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
209261007818	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
209261007819	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
209261007820	dimer interface [polypeptide binding]; other site
209261007821	putative radical transfer pathway; other site
209261007822	diiron center [ion binding]; other site
209261007823	tyrosyl radical; other site
209261007824	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
209261007825	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261007826	dimer interface [polypeptide binding]; other site
209261007827	conserved gate region; other site
209261007828	putative PBP binding loops; other site
209261007829	ABC-ATPase subunit interface; other site
209261007830	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
209261007831	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
209261007832	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
209261007833	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261007834	transcriptional repressor MprA; Provisional; Region: PRK10870
209261007835	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
209261007836	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
209261007837	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
209261007838	HlyD family secretion protein; Region: HlyD_3; pfam13437
209261007839	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
209261007840	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261007841	putative substrate translocation pore; other site
209261007842	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261007843	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
209261007844	S-ribosylhomocysteinase; Provisional; Region: PRK02260
209261007845	glutamate--cysteine ligase; Provisional; Region: PRK02107
209261007846	Predicted membrane protein [Function unknown]; Region: COG1238
209261007847	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
209261007848	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261007849	motif II; other site
209261007850	carbon storage regulator; Provisional; Region: PRK01712
209261007851	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
209261007852	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
209261007853	motif 1; other site
209261007854	active site
209261007855	motif 2; other site
209261007856	motif 3; other site
209261007857	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
209261007858	DHHA1 domain; Region: DHHA1; pfam02272
209261007859	recombination regulator RecX; Reviewed; Region: recX; PRK00117
209261007860	recombinase A; Provisional; Region: recA; PRK09354
209261007861	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
209261007862	hexamer interface [polypeptide binding]; other site
209261007863	Walker A motif; other site
209261007864	ATP binding site [chemical binding]; other site
209261007865	Walker B motif; other site
209261007866	hypothetical protein; Validated; Region: PRK03661
209261007867	Transglycosylase SLT domain; Region: SLT_2; pfam13406
209261007868	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
209261007869	N-acetyl-D-glucosamine binding site [chemical binding]; other site
209261007870	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
209261007871	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
209261007872	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
209261007873	Nucleoside recognition; Region: Gate; pfam07670
209261007874	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
209261007875	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
209261007876	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
209261007877	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
209261007878	putative NAD(P) binding site [chemical binding]; other site
209261007879	active site
209261007880	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
209261007881	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
209261007882	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
209261007883	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261007884	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
209261007885	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
209261007886	putative active site [active]
209261007887	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
209261007888	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
209261007889	GAF domain; Region: GAF; pfam01590
209261007890	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261007891	Walker A motif; other site
209261007892	ATP binding site [chemical binding]; other site
209261007893	Walker B motif; other site
209261007894	arginine finger; other site
209261007895	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
209261007896	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
209261007897	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
209261007898	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
209261007899	iron binding site [ion binding]; other site
209261007900	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
209261007901	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
209261007902	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261007903	Acylphosphatase; Region: Acylphosphatase; pfam00708
209261007904	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
209261007905	HypF finger; Region: zf-HYPF; pfam07503
209261007906	HypF finger; Region: zf-HYPF; pfam07503
209261007907	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
209261007908	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
209261007909	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
209261007910	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
209261007911	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
209261007912	nickel binding site [ion binding]; other site
209261007913	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
209261007914	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
209261007915	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
209261007916	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
209261007917	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
209261007918	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
209261007919	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
209261007920	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
209261007921	NADH dehydrogenase; Region: NADHdh; cl00469
209261007922	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
209261007923	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
209261007924	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
209261007925	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
209261007926	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
209261007927	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
209261007928	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
209261007929	hydrogenase assembly chaperone; Provisional; Region: PRK10409
209261007930	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
209261007931	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
209261007932	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
209261007933	dimerization interface [polypeptide binding]; other site
209261007934	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
209261007935	ATP binding site [chemical binding]; other site
209261007936	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
209261007937	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
209261007938	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
209261007939	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261007940	Walker A motif; other site
209261007941	ATP binding site [chemical binding]; other site
209261007942	Walker B motif; other site
209261007943	arginine finger; other site
209261007944	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
209261007945	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
209261007946	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
209261007947	metal binding site [ion binding]; metal-binding site
209261007948	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
209261007949	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
209261007950	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
209261007951	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
209261007952	ABC-ATPase subunit  interface; other site
209261007953	dimer interface [polypeptide binding]; other site
209261007954	putative PBP binding regions; other site
209261007955	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
209261007956	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
209261007957	ABC-ATPase subunit  interface; other site
209261007958	dimer interface [polypeptide binding]; other site
209261007959	putative PBP binding regions; other site
209261007960	transcriptional activator SprB; Provisional; Region: PRK15320
209261007961	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
209261007962	transcriptional regulator SirC; Provisional; Region: PRK15044
209261007963	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261007964	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
209261007965	invasion protein OrgB; Provisional; Region: PRK15322
209261007966	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
209261007967	invasion protein OrgA; Provisional; Region: PRK15323
209261007968	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
209261007969	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
209261007970	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
209261007971	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
209261007972	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
209261007973	transcriptional regulator HilD; Provisional; Region: PRK15185
209261007974	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261007975	invasion protein regulator; Provisional; Region: PRK12370
209261007976	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261007977	DNA binding site [nucleotide binding]
209261007978	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
209261007979	binding surface
209261007980	TPR motif; other site
209261007981	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
209261007982	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
209261007983	N-acetyl-D-glucosamine binding site [chemical binding]; other site
209261007984	catalytic residue [active]
209261007985	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
209261007986	SicP binding; Region: SicP-binding; pfam09119
209261007987	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
209261007988	switch II binding region; other site
209261007989	Rac1 P-loop interaction site [polypeptide binding]; other site
209261007990	GTP binding residues [chemical binding]; other site
209261007991	switch I binding region; other site
209261007992	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
209261007993	active site
209261007994	chaperone protein SicP; Provisional; Region: PRK15329
209261007995	putative acyl carrier protein IacP; Validated; Region: PRK08172
209261007996	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
209261007997	cell invasion protein SipD; Provisional; Region: PRK15330
209261007998	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
209261007999	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
209261008000	chaperone protein SicA; Provisional; Region: PRK15331
209261008001	Tetratricopeptide repeat; Region: TPR_3; pfam07720
209261008002	Tetratricopeptide repeat; Region: TPR_3; pfam07720
209261008003	type III secretion system protein SpaS; Validated; Region: PRK08156
209261008004	type III secretion system protein SpaR; Provisional; Region: PRK15332
209261008005	type III secretion system protein SpaQ; Provisional; Region: PRK15333
209261008006	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
209261008007	type III secretion system protein SpaO; Validated; Region: PRK08158
209261008008	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
209261008009	antigen presentation protein SpaN; Provisional; Region: PRK15334
209261008010	Surface presentation of antigens protein; Region: SPAN; pfam02510
209261008011	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
209261008012	ATP synthase SpaL; Validated; Region: PRK08149
209261008013	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
209261008014	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
209261008015	Walker A motif; other site
209261008016	ATP binding site [chemical binding]; other site
209261008017	Walker B motif; other site
209261008018	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
209261008019	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
209261008020	type III secretion system protein InvA; Provisional; Region: PRK15337
209261008021	type III secretion system regulator InvE; Provisional; Region: PRK15338
209261008022	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
209261008023	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
209261008024	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
209261008025	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
209261008026	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
209261008027	transcriptional regulator InvF; Provisional; Region: PRK15340
209261008028	InvH outer membrane lipoprotein; Region: InvH; pfam04741
209261008029	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
209261008030	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
209261008031	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
209261008032	active site
209261008033	metal binding site [ion binding]; metal-binding site
209261008034	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
209261008035	MutS domain I; Region: MutS_I; pfam01624
209261008036	MutS domain II; Region: MutS_II; pfam05188
209261008037	MutS domain III; Region: MutS_III; pfam05192
209261008038	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
209261008039	Walker A/P-loop; other site
209261008040	ATP binding site [chemical binding]; other site
209261008041	Q-loop/lid; other site
209261008042	ABC transporter signature motif; other site
209261008043	Walker B; other site
209261008044	D-loop; other site
209261008045	H-loop/switch region; other site
209261008046	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
209261008047	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261008048	Major Facilitator Superfamily; Region: MFS_1; pfam07690
209261008049	putative substrate translocation pore; other site
209261008050	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261008051	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261008052	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
209261008053	putative effector binding pocket; other site
209261008054	dimerization interface [polypeptide binding]; other site
209261008055	GntP family permease; Region: GntP_permease; pfam02447
209261008056	fructuronate transporter; Provisional; Region: PRK10034; cl15264
209261008057	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
209261008058	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
209261008059	putative NAD(P) binding site [chemical binding]; other site
209261008060	active site
209261008061	putative substrate binding site [chemical binding]; other site
209261008062	hypothetical protein; Provisional; Region: PRK09989
209261008063	putative aldolase; Validated; Region: PRK08130
209261008064	intersubunit interface [polypeptide binding]; other site
209261008065	active site
209261008066	Zn2+ binding site [ion binding]; other site
209261008067	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
209261008068	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
209261008069	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261008070	MarR family; Region: MarR_2; cl17246
209261008071	Transcriptional regulators [Transcription]; Region: MarR; COG1846
209261008072	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
209261008073	Flavoprotein; Region: Flavoprotein; pfam02441
209261008074	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
209261008075	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
209261008076	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
209261008077	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
209261008078	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
209261008079	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
209261008080	DNA binding residues [nucleotide binding]
209261008081	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
209261008082	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
209261008083	Peptidase family M23; Region: Peptidase_M23; pfam01551
209261008084	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
209261008085	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261008086	S-adenosylmethionine binding site [chemical binding]; other site
209261008087	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
209261008088	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
209261008089	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
209261008090	Permutation of conserved domain; other site
209261008091	active site
209261008092	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
209261008093	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
209261008094	homotrimer interaction site [polypeptide binding]; other site
209261008095	zinc binding site [ion binding]; other site
209261008096	CDP-binding sites; other site
209261008097	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
209261008098	substrate binding site; other site
209261008099	dimer interface; other site
209261008100	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
209261008101	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
209261008102	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
209261008103	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
209261008104	ligand-binding site [chemical binding]; other site
209261008105	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
209261008106	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
209261008107	CysD dimerization site [polypeptide binding]; other site
209261008108	G1 box; other site
209261008109	putative GEF interaction site [polypeptide binding]; other site
209261008110	GTP/Mg2+ binding site [chemical binding]; other site
209261008111	Switch I region; other site
209261008112	G2 box; other site
209261008113	G3 box; other site
209261008114	Switch II region; other site
209261008115	G4 box; other site
209261008116	G5 box; other site
209261008117	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
209261008118	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
209261008119	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
209261008120	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
209261008121	Active Sites [active]
209261008122	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
209261008123	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
209261008124	metal binding site [ion binding]; metal-binding site
209261008125	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
209261008126	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
209261008127	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
209261008128	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
209261008129	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
209261008130	CT1975-like protein; Region: Cas_CT1975; pfam09344
209261008131	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
209261008132	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
209261008133	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
209261008134	DEAD-like helicases superfamily; Region: DEXDc; smart00487
209261008135	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
209261008136	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
209261008137	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
209261008138	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
209261008139	Active Sites [active]
209261008140	sulfite reductase subunit beta; Provisional; Region: PRK13504
209261008141	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
209261008142	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
209261008143	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
209261008144	Flavodoxin; Region: Flavodoxin_1; pfam00258
209261008145	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
209261008146	FAD binding pocket [chemical binding]; other site
209261008147	FAD binding motif [chemical binding]; other site
209261008148	catalytic residues [active]
209261008149	NAD binding pocket [chemical binding]; other site
209261008150	phosphate binding motif [ion binding]; other site
209261008151	beta-alpha-beta structure motif; other site
209261008152	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
209261008153	active site
209261008154	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
209261008155	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
209261008156	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
209261008157	enolase; Provisional; Region: eno; PRK00077
209261008158	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
209261008159	dimer interface [polypeptide binding]; other site
209261008160	metal binding site [ion binding]; metal-binding site
209261008161	substrate binding pocket [chemical binding]; other site
209261008162	CTP synthetase; Validated; Region: pyrG; PRK05380
209261008163	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
209261008164	Catalytic site [active]
209261008165	active site
209261008166	UTP binding site [chemical binding]; other site
209261008167	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
209261008168	active site
209261008169	putative oxyanion hole; other site
209261008170	catalytic triad [active]
209261008171	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
209261008172	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
209261008173	homodimer interface [polypeptide binding]; other site
209261008174	metal binding site [ion binding]; metal-binding site
209261008175	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
209261008176	homodimer interface [polypeptide binding]; other site
209261008177	active site
209261008178	putative chemical substrate binding site [chemical binding]; other site
209261008179	metal binding site [ion binding]; metal-binding site
209261008180	putative fimbrial outer membrane usher protein SteB; Provisional; Region: PRK15273
209261008181	PapC N-terminal domain; Region: PapC_N; pfam13954
209261008182	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
209261008183	PapC C-terminal domain; Region: PapC_C; pfam13953
209261008184	putative periplasmic fimbrial chaperone protein SteC; Provisional; Region: PRK15274
209261008185	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261008186	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261008187	putative fimbrial protein SteD; Provisional; Region: PRK15275
209261008188	putative fimbrial subunit SteE; Provisional; Region: PRK15276
209261008189	fimbrial protein SteF; Provisional; Region: PRK15260
209261008190	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
209261008191	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
209261008192	HD domain; Region: HD_4; pfam13328
209261008193	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
209261008194	synthetase active site [active]
209261008195	NTP binding site [chemical binding]; other site
209261008196	metal binding site [ion binding]; metal-binding site
209261008197	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
209261008198	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
209261008199	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
209261008200	TRAM domain; Region: TRAM; pfam01938
209261008201	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261008202	S-adenosylmethionine binding site [chemical binding]; other site
209261008203	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
209261008204	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
209261008205	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261008206	dimerization interface [polypeptide binding]; other site
209261008207	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261008208	dimer interface [polypeptide binding]; other site
209261008209	phosphorylation site [posttranslational modification]
209261008210	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261008211	ATP binding site [chemical binding]; other site
209261008212	Mg2+ binding site [ion binding]; other site
209261008213	G-X-G motif; other site
209261008214	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
209261008215	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261008216	active site
209261008217	phosphorylation site [posttranslational modification]
209261008218	intermolecular recognition site; other site
209261008219	dimerization interface [polypeptide binding]; other site
209261008220	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
209261008221	putative binding surface; other site
209261008222	active site
209261008223	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
209261008224	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
209261008225	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
209261008226	active site
209261008227	tetramer interface [polypeptide binding]; other site
209261008228	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
209261008229	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
209261008230	active site
209261008231	tetramer interface [polypeptide binding]; other site
209261008232	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261008233	D-galactonate transporter; Region: 2A0114; TIGR00893
209261008234	putative substrate translocation pore; other site
209261008235	flavodoxin; Provisional; Region: PRK08105
209261008236	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
209261008237	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
209261008238	probable active site [active]
209261008239	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
209261008240	SecY interacting protein Syd; Provisional; Region: PRK04968
209261008241	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
209261008242	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
209261008243	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
209261008244	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
209261008245	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
209261008246	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
209261008247	serine transporter; Region: stp; TIGR00814
209261008248	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
209261008249	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
209261008250	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
209261008251	flap endonuclease-like protein; Provisional; Region: PRK09482
209261008252	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
209261008253	active site
209261008254	metal binding site 1 [ion binding]; metal-binding site
209261008255	putative 5' ssDNA interaction site; other site
209261008256	metal binding site 3; metal-binding site
209261008257	metal binding site 2 [ion binding]; metal-binding site
209261008258	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
209261008259	putative DNA binding site [nucleotide binding]; other site
209261008260	putative metal binding site [ion binding]; other site
209261008261	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
209261008262	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
209261008263	dimer interface [polypeptide binding]; other site
209261008264	active site
209261008265	metal binding site [ion binding]; metal-binding site
209261008266	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
209261008267	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
209261008268	intersubunit interface [polypeptide binding]; other site
209261008269	active site
209261008270	Zn2+ binding site [ion binding]; other site
209261008271	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
209261008272	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261008273	putative substrate translocation pore; other site
209261008274	L-fucose isomerase; Provisional; Region: fucI; PRK10991
209261008275	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
209261008276	hexamer (dimer of trimers) interface [polypeptide binding]; other site
209261008277	trimer interface [polypeptide binding]; other site
209261008278	substrate binding site [chemical binding]; other site
209261008279	Mn binding site [ion binding]; other site
209261008280	L-fuculokinase; Provisional; Region: PRK10331
209261008281	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
209261008282	nucleotide binding site [chemical binding]; other site
209261008283	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
209261008284	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
209261008285	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
209261008286	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261008287	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
209261008288	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
209261008289	hypothetical protein; Provisional; Region: PRK10873
209261008290	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
209261008291	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261008292	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
209261008293	dimerization interface [polypeptide binding]; other site
209261008294	substrate binding pocket [chemical binding]; other site
209261008295	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
209261008296	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
209261008297	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
209261008298	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
209261008299	catalytic residue [active]
209261008300	CsdA-binding activator; Provisional; Region: PRK15019
209261008301	Predicted permeases [General function prediction only]; Region: RarD; COG2962
209261008302	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
209261008303	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
209261008304	putative ATP binding site [chemical binding]; other site
209261008305	putative substrate interface [chemical binding]; other site
209261008306	murein transglycosylase A; Provisional; Region: mltA; PRK11162
209261008307	murein hydrolase B; Provisional; Region: PRK10760; cl17906
209261008308	MltA specific insert domain; Region: MltA; pfam03562
209261008309	3D domain; Region: 3D; pfam06725
209261008310	AMIN domain; Region: AMIN; pfam11741
209261008311	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
209261008312	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
209261008313	active site
209261008314	metal binding site [ion binding]; metal-binding site
209261008315	N-acetylglutamate synthase; Validated; Region: PRK05279
209261008316	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
209261008317	putative feedback inhibition sensing region; other site
209261008318	putative nucleotide binding site [chemical binding]; other site
209261008319	putative substrate binding site [chemical binding]; other site
209261008320	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261008321	Coenzyme A binding pocket [chemical binding]; other site
209261008322	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
209261008323	AAA domain; Region: AAA_30; pfam13604
209261008324	Family description; Region: UvrD_C_2; pfam13538
209261008325	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
209261008326	protease3; Provisional; Region: PRK15101
209261008327	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
209261008328	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
209261008329	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
209261008330	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
209261008331	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
209261008332	hypothetical protein; Provisional; Region: PRK10332
209261008333	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
209261008334	hypothetical protein; Provisional; Region: PRK11521
209261008335	hypothetical protein; Provisional; Region: PRK10557
209261008336	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
209261008337	hypothetical protein; Provisional; Region: PRK10506
209261008338	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
209261008339	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261008340	thymidylate synthase; Reviewed; Region: thyA; PRK01827
209261008341	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
209261008342	dimerization interface [polypeptide binding]; other site
209261008343	active site
209261008344	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
209261008345	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
209261008346	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
209261008347	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
209261008348	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
209261008349	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
209261008350	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
209261008351	putative active site [active]
209261008352	Ap4A binding site [chemical binding]; other site
209261008353	nudix motif; other site
209261008354	putative metal binding site [ion binding]; other site
209261008355	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
209261008356	putative DNA-binding cleft [nucleotide binding]; other site
209261008357	putative DNA clevage site; other site
209261008358	molecular lever; other site
209261008359	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
209261008360	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
209261008361	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
209261008362	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
209261008363	active site
209261008364	catalytic tetrad [active]
209261008365	lysophospholipid transporter LplT; Provisional; Region: PRK11195
209261008366	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261008367	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
209261008368	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
209261008369	putative acyl-acceptor binding pocket; other site
209261008370	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
209261008371	acyl-activating enzyme (AAE) consensus motif; other site
209261008372	putative AMP binding site [chemical binding]; other site
209261008373	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261008374	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
209261008375	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261008376	DNA binding site [nucleotide binding]
209261008377	domain linker motif; other site
209261008378	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
209261008379	dimerization interface (closed form) [polypeptide binding]; other site
209261008380	ligand binding site [chemical binding]; other site
209261008381	Transcriptional regulators [Transcription]; Region: PurR; COG1609
209261008382	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261008383	DNA binding site [nucleotide binding]
209261008384	domain linker motif; other site
209261008385	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
209261008386	dimerization interface (closed form) [polypeptide binding]; other site
209261008387	ligand binding site [chemical binding]; other site
209261008388	diaminopimelate decarboxylase; Provisional; Region: PRK11165
209261008389	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
209261008390	active site
209261008391	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
209261008392	substrate binding site [chemical binding]; other site
209261008393	catalytic residues [active]
209261008394	dimer interface [polypeptide binding]; other site
209261008395	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
209261008396	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261008397	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
209261008398	dimerization interface [polypeptide binding]; other site
209261008399	putative racemase; Provisional; Region: PRK10200
209261008400	aspartate racemase; Region: asp_race; TIGR00035
209261008401	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
209261008402	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261008403	putative substrate translocation pore; other site
209261008404	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261008405	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
209261008406	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
209261008407	NADP binding site [chemical binding]; other site
209261008408	homodimer interface [polypeptide binding]; other site
209261008409	active site
209261008410	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
209261008411	putative acyltransferase; Provisional; Region: PRK05790
209261008412	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
209261008413	dimer interface [polypeptide binding]; other site
209261008414	active site
209261008415	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261008416	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261008417	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
209261008418	dimerization interface [polypeptide binding]; other site
209261008419	Predicted membrane protein [Function unknown]; Region: COG4125
209261008420	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
209261008421	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
209261008422	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
209261008423	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
209261008424	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
209261008425	putative metal binding site [ion binding]; other site
209261008426	putative homodimer interface [polypeptide binding]; other site
209261008427	putative homotetramer interface [polypeptide binding]; other site
209261008428	putative homodimer-homodimer interface [polypeptide binding]; other site
209261008429	putative allosteric switch controlling residues; other site
209261008430	transcriptional activator SprB; Provisional; Region: PRK15320
209261008431	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14600
209261008432	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
209261008433	Fimbrial protein; Region: Fimbrial; pfam00419
209261008434	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
209261008435	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261008436	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261008437	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
209261008438	PapC N-terminal domain; Region: PapC_N; pfam13954
209261008439	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
209261008440	PapC C-terminal domain; Region: PapC_C; pfam13953
209261008441	fimbrial protein StdA; Provisional; Region: PRK15210
209261008442	hypothetical protein; Provisional; Region: PRK10316
209261008443	YfdX protein; Region: YfdX; pfam10938
209261008444	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
209261008445	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
209261008446	oligomeric interface; other site
209261008447	putative active site [active]
209261008448	homodimer interface [polypeptide binding]; other site
209261008449	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
209261008450	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
209261008451	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
209261008452	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
209261008453	INT_SG2, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 2, C-terminal catalytic domain. The CD contains mainly predicted integrase/recombinases and phage-related integrases. Some have N-terminal domains, which show little sequence...; Region: INT_SG2_C; cd01184
209261008454	Int/Topo IB signature motif; other site
209261008455	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
209261008456	Peptidase family M23; Region: Peptidase_M23; pfam01551
209261008457	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
209261008458	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
209261008459	active site
209261008460	metal binding site [ion binding]; metal-binding site
209261008461	nudix motif; other site
209261008462	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
209261008463	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
209261008464	dimer interface [polypeptide binding]; other site
209261008465	putative anticodon binding site; other site
209261008466	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
209261008467	motif 1; other site
209261008468	active site
209261008469	motif 2; other site
209261008470	motif 3; other site
209261008471	peptide chain release factor 2; Validated; Region: prfB; PRK00578
209261008472	This domain is found in peptide chain release factors; Region: PCRF; smart00937
209261008473	RF-1 domain; Region: RF-1; pfam00472
209261008474	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
209261008475	DHH family; Region: DHH; pfam01368
209261008476	DHHA1 domain; Region: DHHA1; pfam02272
209261008477	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
209261008478	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
209261008479	dimerization domain [polypeptide binding]; other site
209261008480	dimer interface [polypeptide binding]; other site
209261008481	catalytic residues [active]
209261008482	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
209261008483	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
209261008484	active site
209261008485	Int/Topo IB signature motif; other site
209261008486	flavodoxin FldB; Provisional; Region: PRK12359
209261008487	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
209261008488	hypothetical protein; Provisional; Region: PRK10878
209261008489	putative global regulator; Reviewed; Region: PRK09559
209261008490	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
209261008491	hemolysin; Provisional; Region: PRK15087
209261008492	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
209261008493	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
209261008494	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
209261008495	beta-galactosidase; Region: BGL; TIGR03356
209261008496	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
209261008497	glycine dehydrogenase; Provisional; Region: PRK05367
209261008498	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
209261008499	tetramer interface [polypeptide binding]; other site
209261008500	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261008501	catalytic residue [active]
209261008502	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
209261008503	tetramer interface [polypeptide binding]; other site
209261008504	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261008505	catalytic residue [active]
209261008506	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
209261008507	lipoyl attachment site [posttranslational modification]; other site
209261008508	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
209261008509	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
209261008510	oxidoreductase; Provisional; Region: PRK08013
209261008511	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
209261008512	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
209261008513	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
209261008514	proline aminopeptidase P II; Provisional; Region: PRK10879
209261008515	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
209261008516	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
209261008517	active site
209261008518	hypothetical protein; Reviewed; Region: PRK01736
209261008519	Z-ring-associated protein; Provisional; Region: PRK10972
209261008520	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
209261008521	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
209261008522	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
209261008523	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
209261008524	ligand binding site [chemical binding]; other site
209261008525	NAD binding site [chemical binding]; other site
209261008526	tetramer interface [polypeptide binding]; other site
209261008527	catalytic site [active]
209261008528	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
209261008529	L-serine binding site [chemical binding]; other site
209261008530	ACT domain interface; other site
209261008531	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
209261008532	tetramer (dimer of dimers) interface [polypeptide binding]; other site
209261008533	active site
209261008534	dimer interface [polypeptide binding]; other site
209261008535	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
209261008536	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261008537	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
209261008538	putative dimerization interface [polypeptide binding]; other site
209261008539	Uncharacterized conserved protein [Function unknown]; Region: COG2968
209261008540	oxidative stress defense protein; Provisional; Region: PRK11087
209261008541	arginine exporter protein; Provisional; Region: PRK09304
209261008542	mechanosensitive channel MscS; Provisional; Region: PRK10334
209261008543	Mechanosensitive ion channel; Region: MS_channel; pfam00924
209261008544	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261008545	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
209261008546	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
209261008547	active site
209261008548	intersubunit interface [polypeptide binding]; other site
209261008549	zinc binding site [ion binding]; other site
209261008550	Na+ binding site [ion binding]; other site
209261008551	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
209261008552	Phosphoglycerate kinase; Region: PGK; pfam00162
209261008553	substrate binding site [chemical binding]; other site
209261008554	hinge regions; other site
209261008555	ADP binding site [chemical binding]; other site
209261008556	catalytic site [active]
209261008557	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
209261008558	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
209261008559	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
209261008560	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
209261008561	trimer interface [polypeptide binding]; other site
209261008562	putative Zn binding site [ion binding]; other site
209261008563	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
209261008564	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
209261008565	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
209261008566	Walker A/P-loop; other site
209261008567	ATP binding site [chemical binding]; other site
209261008568	Q-loop/lid; other site
209261008569	ABC transporter signature motif; other site
209261008570	Walker B; other site
209261008571	D-loop; other site
209261008572	H-loop/switch region; other site
209261008573	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
209261008574	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
209261008575	Walker A/P-loop; other site
209261008576	ATP binding site [chemical binding]; other site
209261008577	Q-loop/lid; other site
209261008578	ABC transporter signature motif; other site
209261008579	Walker B; other site
209261008580	D-loop; other site
209261008581	H-loop/switch region; other site
209261008582	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261008583	transketolase; Reviewed; Region: PRK12753
209261008584	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
209261008585	TPP-binding site [chemical binding]; other site
209261008586	dimer interface [polypeptide binding]; other site
209261008587	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
209261008588	PYR/PP interface [polypeptide binding]; other site
209261008589	dimer interface [polypeptide binding]; other site
209261008590	TPP binding site [chemical binding]; other site
209261008591	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
209261008592	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
209261008593	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
209261008594	agmatinase; Region: agmatinase; TIGR01230
209261008595	oligomer interface [polypeptide binding]; other site
209261008596	putative active site [active]
209261008597	Mn binding site [ion binding]; other site
209261008598	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
209261008599	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
209261008600	dimer interface [polypeptide binding]; other site
209261008601	active site
209261008602	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
209261008603	catalytic residues [active]
209261008604	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
209261008605	Virulence promoting factor; Region: YqgB; pfam11036
209261008606	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
209261008607	S-adenosylmethionine synthetase; Validated; Region: PRK05250
209261008608	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
209261008609	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
209261008610	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
209261008611	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
209261008612	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261008613	putative substrate translocation pore; other site
209261008614	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261008615	hypothetical protein; Provisional; Region: PRK04860
209261008616	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
209261008617	DNA-specific endonuclease I; Provisional; Region: PRK15137
209261008618	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
209261008619	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
209261008620	RNA methyltransferase, RsmE family; Region: TIGR00046
209261008621	glutathione synthetase; Provisional; Region: PRK05246
209261008622	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
209261008623	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
209261008624	hypothetical protein; Validated; Region: PRK00228
209261008625	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
209261008626	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
209261008627	Transcriptional regulator [Transcription]; Region: IclR; COG1414
209261008628	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
209261008629	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
209261008630	Walker A motif; other site
209261008631	ATP binding site [chemical binding]; other site
209261008632	Walker B motif; other site
209261008633	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
209261008634	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
209261008635	catalytic residue [active]
209261008636	YGGT family; Region: YGGT; pfam02325
209261008637	YGGT family; Region: YGGT; pfam02325
209261008638	hypothetical protein; Validated; Region: PRK05090
209261008639	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
209261008640	active site
209261008641	dimerization interface [polypeptide binding]; other site
209261008642	HemN family oxidoreductase; Provisional; Region: PRK05660
209261008643	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261008644	FeS/SAM binding site; other site
209261008645	HemN C-terminal domain; Region: HemN_C; pfam06969
209261008646	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
209261008647	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
209261008648	homodimer interface [polypeptide binding]; other site
209261008649	active site
209261008650	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261008651	hypothetical protein; Provisional; Region: PRK10626
209261008652	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
209261008653	hypothetical protein; Provisional; Region: PRK11702
209261008654	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
209261008655	adenine DNA glycosylase; Provisional; Region: PRK10880
209261008656	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
209261008657	minor groove reading motif; other site
209261008658	helix-hairpin-helix signature motif; other site
209261008659	substrate binding pocket [chemical binding]; other site
209261008660	active site
209261008661	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
209261008662	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
209261008663	DNA binding and oxoG recognition site [nucleotide binding]
209261008664	oxidative damage protection protein; Provisional; Region: PRK05408
209261008665	murein transglycosylase C; Provisional; Region: mltC; PRK11671
209261008666	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
209261008667	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
209261008668	N-acetyl-D-glucosamine binding site [chemical binding]; other site
209261008669	catalytic residue [active]
209261008670	nucleoside transporter; Region: 2A0110; TIGR00889
209261008671	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
209261008672	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
209261008673	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
209261008674	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
209261008675	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
209261008676	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
209261008677	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261008678	DNA binding residues [nucleotide binding]
209261008679	dimerization interface [polypeptide binding]; other site
209261008680	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
209261008681	Amino acid permease; Region: AA_permease_2; pfam13520
209261008682	Protein of unknown function (DUF861); Region: Cupin_3; cl17594
209261008683	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
209261008684	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
209261008685	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
209261008686	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
209261008687	NAD(P) binding site [chemical binding]; other site
209261008688	catalytic residues [active]
209261008689	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
209261008690	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
209261008691	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
209261008692	active site
209261008693	catalytic site [active]
209261008694	Zn binding site [ion binding]; other site
209261008695	tetramer interface [polypeptide binding]; other site
209261008696	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
209261008697	Predicted amidohydrolase [General function prediction only]; Region: COG0388
209261008698	active site
209261008699	catalytic triad [active]
209261008700	dimer interface [polypeptide binding]; other site
209261008701	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261008702	D-galactonate transporter; Region: 2A0114; TIGR00893
209261008703	putative substrate translocation pore; other site
209261008704	mannonate dehydratase; Provisional; Region: PRK03906
209261008705	mannonate dehydratase; Region: uxuA; TIGR00695
209261008706	D-mannonate oxidoreductase; Provisional; Region: PRK15037
209261008707	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
209261008708	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
209261008709	Glucuronate isomerase; Region: UxaC; pfam02614
209261008710	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
209261008711	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
209261008712	dimer interface [polypeptide binding]; other site
209261008713	putative CheW interface [polypeptide binding]; other site
209261008714	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
209261008715	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
209261008716	CHAP domain; Region: CHAP; pfam05257
209261008717	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
209261008718	putative S-transferase; Provisional; Region: PRK11752
209261008719	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
209261008720	C-terminal domain interface [polypeptide binding]; other site
209261008721	GSH binding site (G-site) [chemical binding]; other site
209261008722	dimer interface [polypeptide binding]; other site
209261008723	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
209261008724	dimer interface [polypeptide binding]; other site
209261008725	N-terminal domain interface [polypeptide binding]; other site
209261008726	active site
209261008727	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
209261008728	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
209261008729	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
209261008730	putative ligand binding residues [chemical binding]; other site
209261008731	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
209261008732	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
209261008733	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
209261008734	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
209261008735	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
209261008736	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
209261008737	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
209261008738	putative substrate-binding site; other site
209261008739	nickel binding site [ion binding]; other site
209261008740	hydrogenase 2 large subunit; Provisional; Region: PRK10467
209261008741	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
209261008742	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
209261008743	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
209261008744	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
209261008745	4Fe-4S binding domain; Region: Fer4_6; pfam12837
209261008746	hydrogenase 2 small subunit; Provisional; Region: PRK10468
209261008747	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
209261008748	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
209261008749	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
209261008750	hypothetical protein; Provisional; Region: PRK05208
209261008751	oxidoreductase; Provisional; Region: PRK07985
209261008752	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
209261008753	NAD binding site [chemical binding]; other site
209261008754	metal binding site [ion binding]; metal-binding site
209261008755	active site
209261008756	biopolymer transport protein ExbD; Provisional; Region: PRK11267
209261008757	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
209261008758	biopolymer transport protein ExbB; Provisional; Region: PRK10414
209261008759	cystathionine beta-lyase; Provisional; Region: PRK08114
209261008760	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
209261008761	homodimer interface [polypeptide binding]; other site
209261008762	substrate-cofactor binding pocket; other site
209261008763	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261008764	catalytic residue [active]
209261008765	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
209261008766	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
209261008767	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
209261008768	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
209261008769	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261008770	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261008771	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
209261008772	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
209261008773	dimer interface [polypeptide binding]; other site
209261008774	active site
209261008775	metal binding site [ion binding]; metal-binding site
209261008776	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
209261008777	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
209261008778	transmembrane helices; other site
209261008779	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
209261008780	nucleotide binding site/active site [active]
209261008781	catalytic residue [active]
209261008782	hypothetical protein; Provisional; Region: PRK01254
209261008783	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
209261008784	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
209261008785	YARHG domain; Region: YARHG; pfam13308
209261008786	FtsI repressor; Provisional; Region: PRK10883
209261008787	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
209261008788	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
209261008789	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
209261008790	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
209261008791	putative acyl-acceptor binding pocket; other site
209261008792	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
209261008793	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
209261008794	CAP-like domain; other site
209261008795	active site
209261008796	primary dimer interface [polypeptide binding]; other site
209261008797	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
209261008798	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
209261008799	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261008800	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
209261008801	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
209261008802	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
209261008803	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261008804	active site
209261008805	phosphorylation site [posttranslational modification]
209261008806	intermolecular recognition site; other site
209261008807	dimerization interface [polypeptide binding]; other site
209261008808	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261008809	DNA binding site [nucleotide binding]
209261008810	sensor protein QseC; Provisional; Region: PRK10337
209261008811	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
209261008812	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261008813	dimer interface [polypeptide binding]; other site
209261008814	phosphorylation site [posttranslational modification]
209261008815	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261008816	ATP binding site [chemical binding]; other site
209261008817	Mg2+ binding site [ion binding]; other site
209261008818	G-X-G motif; other site
209261008819	Uncharacterized conserved protein [Function unknown]; Region: COG1359
209261008820	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
209261008821	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261008822	ATP binding site [chemical binding]; other site
209261008823	Mg2+ binding site [ion binding]; other site
209261008824	G-X-G motif; other site
209261008825	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
209261008826	anchoring element; other site
209261008827	dimer interface [polypeptide binding]; other site
209261008828	ATP binding site [chemical binding]; other site
209261008829	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
209261008830	active site
209261008831	metal binding site [ion binding]; metal-binding site
209261008832	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
209261008833	esterase YqiA; Provisional; Region: PRK11071
209261008834	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
209261008835	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
209261008836	active site
209261008837	metal binding site [ion binding]; metal-binding site
209261008838	hexamer interface [polypeptide binding]; other site
209261008839	putative dehydrogenase; Provisional; Region: PRK11039
209261008840	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
209261008841	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
209261008842	dimer interface [polypeptide binding]; other site
209261008843	ADP-ribose binding site [chemical binding]; other site
209261008844	active site
209261008845	nudix motif; other site
209261008846	metal binding site [ion binding]; metal-binding site
209261008847	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
209261008848	hypothetical protein; Provisional; Region: PRK11653
209261008849	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
209261008850	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
209261008851	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
209261008852	putative active site [active]
209261008853	metal binding site [ion binding]; metal-binding site
209261008854	zinc transporter ZupT; Provisional; Region: PRK04201
209261008855	ZIP Zinc transporter; Region: Zip; pfam02535
209261008856	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
209261008857	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
209261008858	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
209261008859	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
209261008860	catalytic residues [active]
209261008861	hinge region; other site
209261008862	alpha helical domain; other site
209261008863	putative disulfide oxidoreductase; Provisional; Region: PRK04307
209261008864	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
209261008865	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
209261008866	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
209261008867	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
209261008868	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
209261008869	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
209261008870	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
209261008871	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
209261008872	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
209261008873	putative ribose interaction site [chemical binding]; other site
209261008874	putative ADP binding site [chemical binding]; other site
209261008875	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
209261008876	active site
209261008877	nucleotide binding site [chemical binding]; other site
209261008878	HIGH motif; other site
209261008879	KMSKS motif; other site
209261008880	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
209261008881	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
209261008882	metal binding triad; other site
209261008883	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
209261008884	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
209261008885	metal binding triad; other site
209261008886	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
209261008887	Uncharacterized conserved protein [Function unknown]; Region: COG3025
209261008888	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
209261008889	putative active site [active]
209261008890	putative metal binding residues [ion binding]; other site
209261008891	signature motif; other site
209261008892	putative triphosphate binding site [ion binding]; other site
209261008893	CHAD domain; Region: CHAD; pfam05235
209261008894	SH3 domain-containing protein; Provisional; Region: PRK10884
209261008895	Bacterial SH3 domain homologues; Region: SH3b; smart00287
209261008896	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
209261008897	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
209261008898	active site
209261008899	NTP binding site [chemical binding]; other site
209261008900	metal binding triad [ion binding]; metal-binding site
209261008901	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
209261008902	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
209261008903	Zn2+ binding site [ion binding]; other site
209261008904	Mg2+ binding site [ion binding]; other site
209261008905	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
209261008906	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
209261008907	homooctamer interface [polypeptide binding]; other site
209261008908	active site
209261008909	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
209261008910	UGMP family protein; Validated; Region: PRK09604
209261008911	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
209261008912	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
209261008913	DNA primase; Validated; Region: dnaG; PRK05667
209261008914	CHC2 zinc finger; Region: zf-CHC2; pfam01807
209261008915	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
209261008916	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
209261008917	active site
209261008918	metal binding site [ion binding]; metal-binding site
209261008919	interdomain interaction site; other site
209261008920	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
209261008921	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
209261008922	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
209261008923	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
209261008924	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
209261008925	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
209261008926	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
209261008927	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
209261008928	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
209261008929	DNA binding residues [nucleotide binding]
209261008930	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
209261008931	active site
209261008932	SUMO-1 interface [polypeptide binding]; other site
209261008933	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
209261008934	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
209261008935	FAD binding pocket [chemical binding]; other site
209261008936	FAD binding motif [chemical binding]; other site
209261008937	phosphate binding motif [ion binding]; other site
209261008938	NAD binding pocket [chemical binding]; other site
209261008939	Predicted transcriptional regulators [Transcription]; Region: COG1695
209261008940	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
209261008941	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
209261008942	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261008943	dimerization interface [polypeptide binding]; other site
209261008944	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
209261008945	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
209261008946	dimer interface [polypeptide binding]; other site
209261008947	putative CheW interface [polypeptide binding]; other site
209261008948	PAS fold; Region: PAS_3; pfam08447
209261008949	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
209261008950	putative active site [active]
209261008951	heme pocket [chemical binding]; other site
209261008952	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
209261008953	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
209261008954	dimer interface [polypeptide binding]; other site
209261008955	putative CheW interface [polypeptide binding]; other site
209261008956	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
209261008957	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
209261008958	inhibitor-cofactor binding pocket; inhibition site
209261008959	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261008960	catalytic residue [active]
209261008961	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
209261008962	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261008963	S-adenosylmethionine binding site [chemical binding]; other site
209261008964	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
209261008965	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
209261008966	putative active site [active]
209261008967	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
209261008968	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
209261008969	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
209261008970	serine/threonine transporter SstT; Provisional; Region: PRK13628
209261008971	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
209261008972	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
209261008973	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
209261008974	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
209261008975	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
209261008976	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
209261008977	Predicted membrane protein [Function unknown]; Region: COG5393
209261008978	YqjK-like protein; Region: YqjK; pfam13997
209261008979	Predicted membrane protein [Function unknown]; Region: COG2259
209261008980	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
209261008981	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
209261008982	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
209261008983	putative dimer interface [polypeptide binding]; other site
209261008984	N-terminal domain interface [polypeptide binding]; other site
209261008985	putative substrate binding pocket (H-site) [chemical binding]; other site
209261008986	Predicted membrane protein [Function unknown]; Region: COG3152
209261008987	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261008988	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
209261008989	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
209261008990	dimerization interface [polypeptide binding]; other site
209261008991	Pirin-related protein [General function prediction only]; Region: COG1741
209261008992	Pirin; Region: Pirin; pfam02678
209261008993	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
209261008994	L-serine dehydratase TdcG; Provisional; Region: PRK15040
209261008995	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
209261008996	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
209261008997	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
209261008998	Pyruvate formate lyase 1; Region: PFL1; cd01678
209261008999	coenzyme A binding site [chemical binding]; other site
209261009000	active site
209261009001	catalytic residues [active]
209261009002	glycine loop; other site
209261009003	propionate/acetate kinase; Provisional; Region: PRK12379
209261009004	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
209261009005	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
209261009006	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
209261009007	tetramer interface [polypeptide binding]; other site
209261009008	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261009009	catalytic residue [active]
209261009010	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
209261009011	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261009012	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
209261009013	putative substrate binding pocket [chemical binding]; other site
209261009014	putative dimerization interface [polypeptide binding]; other site
209261009015	glycerate kinase I; Provisional; Region: PRK10342
209261009016	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
209261009017	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
209261009018	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
209261009019	galactarate dehydratase; Region: galactar-dH20; TIGR03248
209261009020	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
209261009021	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
209261009022	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
209261009023	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
209261009024	substrate binding site [chemical binding]; other site
209261009025	ATP binding site [chemical binding]; other site
209261009026	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
209261009027	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
209261009028	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261009029	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
209261009030	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
209261009031	intersubunit interface [polypeptide binding]; other site
209261009032	active site
209261009033	zinc binding site [ion binding]; other site
209261009034	Na+ binding site [ion binding]; other site
209261009035	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
209261009036	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
209261009037	putative substrate binding site [chemical binding]; other site
209261009038	putative ATP binding site [chemical binding]; other site
209261009039	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
209261009040	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
209261009041	active site
209261009042	P-loop; other site
209261009043	phosphorylation site [posttranslational modification]
209261009044	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
209261009045	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
209261009046	active site
209261009047	phosphorylation site [posttranslational modification]
209261009048	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
209261009049	dimerization domain swap beta strand [polypeptide binding]; other site
209261009050	regulatory protein interface [polypeptide binding]; other site
209261009051	active site
209261009052	regulatory phosphorylation site [posttranslational modification]; other site
209261009053	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
209261009054	active site
209261009055	phosphorylation site [posttranslational modification]
209261009056	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
209261009057	active site
209261009058	P-loop; other site
209261009059	phosphorylation site [posttranslational modification]
209261009060	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
209261009061	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
209261009062	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
209261009063	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
209261009064	putative NAD(P) binding site [chemical binding]; other site
209261009065	catalytic Zn binding site [ion binding]; other site
209261009066	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
209261009067	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
209261009068	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261009069	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
209261009070	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
209261009071	putative SAM binding site [chemical binding]; other site
209261009072	putative homodimer interface [polypeptide binding]; other site
209261009073	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
209261009074	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
209261009075	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
209261009076	putative ligand binding site [chemical binding]; other site
209261009077	TIGR00252 family protein; Region: TIGR00252
209261009078	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
209261009079	dimer interface [polypeptide binding]; other site
209261009080	active site
209261009081	outer membrane lipoprotein; Provisional; Region: PRK11023
209261009082	BON domain; Region: BON; pfam04972
209261009083	BON domain; Region: BON; pfam04972
209261009084	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
209261009085	NADH(P)-binding; Region: NAD_binding_10; pfam13460
209261009086	NAD binding site [chemical binding]; other site
209261009087	active site
209261009088	intracellular protease, PfpI family; Region: PfpI; TIGR01382
209261009089	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
209261009090	proposed catalytic triad [active]
209261009091	conserved cys residue [active]
209261009092	hypothetical protein; Provisional; Region: PRK03467
209261009093	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
209261009094	GIY-YIG motif/motif A; other site
209261009095	putative active site [active]
209261009096	putative metal binding site [ion binding]; other site
209261009097	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
209261009098	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261009099	Coenzyme A binding pocket [chemical binding]; other site
209261009100	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
209261009101	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
209261009102	Peptidase family U32; Region: Peptidase_U32; pfam01136
209261009103	putative protease; Provisional; Region: PRK15447
209261009104	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
209261009105	hypothetical protein; Provisional; Region: PRK10508
209261009106	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
209261009107	tryptophan permease; Provisional; Region: PRK10483
209261009108	aromatic amino acid transport protein; Region: araaP; TIGR00837
209261009109	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
209261009110	DEAD-like helicases superfamily; Region: DEXDc; smart00487
209261009111	ATP binding site [chemical binding]; other site
209261009112	Mg++ binding site [ion binding]; other site
209261009113	motif III; other site
209261009114	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261009115	nucleotide binding region [chemical binding]; other site
209261009116	ATP-binding site [chemical binding]; other site
209261009117	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
209261009118	putative RNA binding site [nucleotide binding]; other site
209261009119	lipoprotein NlpI; Provisional; Region: PRK11189
209261009120	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
209261009121	binding surface
209261009122	TPR motif; other site
209261009123	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
209261009124	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
209261009125	RNase E interface [polypeptide binding]; other site
209261009126	trimer interface [polypeptide binding]; other site
209261009127	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
209261009128	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
209261009129	RNase E interface [polypeptide binding]; other site
209261009130	trimer interface [polypeptide binding]; other site
209261009131	active site
209261009132	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
209261009133	putative nucleic acid binding region [nucleotide binding]; other site
209261009134	G-X-X-G motif; other site
209261009135	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
209261009136	RNA binding site [nucleotide binding]; other site
209261009137	domain interface; other site
209261009138	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
209261009139	16S/18S rRNA binding site [nucleotide binding]; other site
209261009140	S13e-L30e interaction site [polypeptide binding]; other site
209261009141	25S rRNA binding site [nucleotide binding]; other site
209261009142	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
209261009143	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
209261009144	RNA binding site [nucleotide binding]; other site
209261009145	active site
209261009146	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
209261009147	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
209261009148	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
209261009149	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
209261009150	translation initiation factor IF-2; Region: IF-2; TIGR00487
209261009151	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
209261009152	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
209261009153	G1 box; other site
209261009154	putative GEF interaction site [polypeptide binding]; other site
209261009155	GTP/Mg2+ binding site [chemical binding]; other site
209261009156	Switch I region; other site
209261009157	G2 box; other site
209261009158	G3 box; other site
209261009159	Switch II region; other site
209261009160	G4 box; other site
209261009161	G5 box; other site
209261009162	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
209261009163	Translation-initiation factor 2; Region: IF-2; pfam11987
209261009164	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
209261009165	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
209261009166	NusA N-terminal domain; Region: NusA_N; pfam08529
209261009167	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
209261009168	RNA binding site [nucleotide binding]; other site
209261009169	homodimer interface [polypeptide binding]; other site
209261009170	NusA-like KH domain; Region: KH_5; pfam13184
209261009171	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
209261009172	G-X-X-G motif; other site
209261009173	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
209261009174	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
209261009175	ribosome maturation protein RimP; Reviewed; Region: PRK00092
209261009176	Sm and related proteins; Region: Sm_like; cl00259
209261009177	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
209261009178	putative oligomer interface [polypeptide binding]; other site
209261009179	putative RNA binding site [nucleotide binding]; other site
209261009180	argininosuccinate synthase; Validated; Region: PRK05370
209261009181	argininosuccinate synthase; Provisional; Region: PRK13820
209261009182	Preprotein translocase SecG subunit; Region: SecG; pfam03840
209261009183	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
209261009184	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
209261009185	active site
209261009186	substrate binding site [chemical binding]; other site
209261009187	metal binding site [ion binding]; metal-binding site
209261009188	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
209261009189	dihydropteroate synthase; Region: DHPS; TIGR01496
209261009190	substrate binding pocket [chemical binding]; other site
209261009191	dimer interface [polypeptide binding]; other site
209261009192	inhibitor binding site; inhibition site
209261009193	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
209261009194	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261009195	Walker A motif; other site
209261009196	ATP binding site [chemical binding]; other site
209261009197	Walker B motif; other site
209261009198	arginine finger; other site
209261009199	Peptidase family M41; Region: Peptidase_M41; pfam01434
209261009200	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
209261009201	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261009202	S-adenosylmethionine binding site [chemical binding]; other site
209261009203	RNA-binding protein YhbY; Provisional; Region: PRK10343
209261009204	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
209261009205	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
209261009206	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
209261009207	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
209261009208	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
209261009209	GTPase CgtA; Reviewed; Region: obgE; PRK12298
209261009210	GTP1/OBG; Region: GTP1_OBG; pfam01018
209261009211	Obg GTPase; Region: Obg; cd01898
209261009212	G1 box; other site
209261009213	GTP/Mg2+ binding site [chemical binding]; other site
209261009214	Switch I region; other site
209261009215	G2 box; other site
209261009216	G3 box; other site
209261009217	Switch II region; other site
209261009218	G4 box; other site
209261009219	G5 box; other site
209261009220	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
209261009221	EamA-like transporter family; Region: EamA; pfam00892
209261009222	EamA-like transporter family; Region: EamA; pfam00892
209261009223	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
209261009224	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
209261009225	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
209261009226	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
209261009227	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
209261009228	substrate binding pocket [chemical binding]; other site
209261009229	chain length determination region; other site
209261009230	substrate-Mg2+ binding site; other site
209261009231	catalytic residues [active]
209261009232	aspartate-rich region 1; other site
209261009233	active site lid residues [active]
209261009234	aspartate-rich region 2; other site
209261009235	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
209261009236	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
209261009237	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
209261009238	hinge; other site
209261009239	active site
209261009240	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
209261009241	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
209261009242	anti sigma factor interaction site; other site
209261009243	regulatory phosphorylation site [posttranslational modification]; other site
209261009244	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
209261009245	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
209261009246	mce related protein; Region: MCE; pfam02470
209261009247	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
209261009248	conserved hypothetical integral membrane protein; Region: TIGR00056
209261009249	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
209261009250	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
209261009251	Walker A/P-loop; other site
209261009252	ATP binding site [chemical binding]; other site
209261009253	Q-loop/lid; other site
209261009254	ABC transporter signature motif; other site
209261009255	Walker B; other site
209261009256	D-loop; other site
209261009257	H-loop/switch region; other site
209261009258	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
209261009259	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
209261009260	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
209261009261	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
209261009262	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
209261009263	putative active site [active]
209261009264	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
209261009265	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
209261009266	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
209261009267	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
209261009268	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
209261009269	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
209261009270	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
209261009271	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
209261009272	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
209261009273	Walker A/P-loop; other site
209261009274	ATP binding site [chemical binding]; other site
209261009275	Q-loop/lid; other site
209261009276	ABC transporter signature motif; other site
209261009277	Walker B; other site
209261009278	D-loop; other site
209261009279	H-loop/switch region; other site
209261009280	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
209261009281	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
209261009282	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
209261009283	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
209261009284	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
209261009285	30S subunit binding site; other site
209261009286	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
209261009287	active site
209261009288	phosphorylation site [posttranslational modification]
209261009289	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
209261009290	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
209261009291	dimerization domain swap beta strand [polypeptide binding]; other site
209261009292	regulatory protein interface [polypeptide binding]; other site
209261009293	active site
209261009294	regulatory phosphorylation site [posttranslational modification]; other site
209261009295	hypothetical protein; Provisional; Region: PRK10345
209261009296	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
209261009297	Transglycosylase; Region: Transgly; cl17702
209261009298	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
209261009299	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
209261009300	conserved cys residue [active]
209261009301	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
209261009302	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
209261009303	putative active site [active]
209261009304	heme pocket [chemical binding]; other site
209261009305	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261009306	dimer interface [polypeptide binding]; other site
209261009307	phosphorylation site [posttranslational modification]
209261009308	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261009309	ATP binding site [chemical binding]; other site
209261009310	Mg2+ binding site [ion binding]; other site
209261009311	G-X-G motif; other site
209261009312	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261009313	active site
209261009314	phosphorylation site [posttranslational modification]
209261009315	intermolecular recognition site; other site
209261009316	dimerization interface [polypeptide binding]; other site
209261009317	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
209261009318	putative binding surface; other site
209261009319	active site
209261009320	radical SAM protein, TIGR01212 family; Region: TIGR01212
209261009321	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261009322	FeS/SAM binding site; other site
209261009323	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
209261009324	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
209261009325	active site
209261009326	dimer interface [polypeptide binding]; other site
209261009327	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
209261009328	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
209261009329	active site
209261009330	FMN binding site [chemical binding]; other site
209261009331	substrate binding site [chemical binding]; other site
209261009332	3Fe-4S cluster binding site [ion binding]; other site
209261009333	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
209261009334	domain interface; other site
209261009335	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
209261009336	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
209261009337	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261009338	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
209261009339	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
209261009340	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
209261009341	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
209261009342	Na binding site [ion binding]; other site
209261009343	putative substrate binding site [chemical binding]; other site
209261009344	cytosine deaminase; Provisional; Region: PRK09230
209261009345	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
209261009346	active site
209261009347	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
209261009348	N-acetylmannosamine kinase; Provisional; Region: PRK05082
209261009349	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
209261009350	nucleotide binding site [chemical binding]; other site
209261009351	putative sialic acid transporter; Provisional; Region: PRK03893
209261009352	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261009353	putative substrate translocation pore; other site
209261009354	N-acetylneuraminate lyase; Provisional; Region: PRK04147
209261009355	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
209261009356	inhibitor site; inhibition site
209261009357	active site
209261009358	dimer interface [polypeptide binding]; other site
209261009359	catalytic residue [active]
209261009360	transcriptional regulator NanR; Provisional; Region: PRK03837
209261009361	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261009362	DNA-binding site [nucleotide binding]; DNA binding site
209261009363	FCD domain; Region: FCD; pfam07729
209261009364	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
209261009365	stringent starvation protein A; Provisional; Region: sspA; PRK09481
209261009366	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
209261009367	C-terminal domain interface [polypeptide binding]; other site
209261009368	putative GSH binding site (G-site) [chemical binding]; other site
209261009369	dimer interface [polypeptide binding]; other site
209261009370	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
209261009371	dimer interface [polypeptide binding]; other site
209261009372	N-terminal domain interface [polypeptide binding]; other site
209261009373	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
209261009374	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
209261009375	23S rRNA interface [nucleotide binding]; other site
209261009376	L3 interface [polypeptide binding]; other site
209261009377	Predicted ATPase [General function prediction only]; Region: COG1485
209261009378	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
209261009379	hypothetical protein; Provisional; Region: PRK11677
209261009380	serine endoprotease; Provisional; Region: PRK10139
209261009381	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
209261009382	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
209261009383	protein binding site [polypeptide binding]; other site
209261009384	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
209261009385	serine endoprotease; Provisional; Region: PRK10898
209261009386	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
209261009387	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
209261009388	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
209261009389	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
209261009390	oxaloacetate decarboxylase; Provisional; Region: PRK14040
209261009391	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
209261009392	active site
209261009393	catalytic residues [active]
209261009394	metal binding site [ion binding]; metal-binding site
209261009395	homodimer binding site [polypeptide binding]; other site
209261009396	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
209261009397	carboxyltransferase (CT) interaction site; other site
209261009398	biotinylation site [posttranslational modification]; other site
209261009399	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
209261009400	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
209261009401	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
209261009402	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
209261009403	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
209261009404	transmembrane helices; other site
209261009405	Transcriptional regulators [Transcription]; Region: FadR; COG2186
209261009406	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261009407	DNA-binding site [nucleotide binding]; DNA binding site
209261009408	FCD domain; Region: FCD; pfam07729
209261009409	Transcriptional regulators [Transcription]; Region: GntR; COG1802
209261009410	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261009411	DNA-binding site [nucleotide binding]; DNA binding site
209261009412	malate dehydrogenase; Provisional; Region: PRK05086
209261009413	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
209261009414	NAD binding site [chemical binding]; other site
209261009415	dimerization interface [polypeptide binding]; other site
209261009416	Substrate binding site [chemical binding]; other site
209261009417	arginine repressor; Provisional; Region: PRK05066
209261009418	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
209261009419	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
209261009420	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
209261009421	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
209261009422	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
209261009423	RNAase interaction site [polypeptide binding]; other site
209261009424	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
209261009425	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
209261009426	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
209261009427	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
209261009428	HlyD family secretion protein; Region: HlyD_3; pfam13437
209261009429	efflux system membrane protein; Provisional; Region: PRK11594
209261009430	transcriptional regulator; Provisional; Region: PRK10632
209261009431	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261009432	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
209261009433	putative effector binding pocket; other site
209261009434	dimerization interface [polypeptide binding]; other site
209261009435	protease TldD; Provisional; Region: tldD; PRK10735
209261009436	hypothetical protein; Provisional; Region: PRK10899
209261009437	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
209261009438	ribonuclease G; Provisional; Region: PRK11712
209261009439	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
209261009440	homodimer interface [polypeptide binding]; other site
209261009441	oligonucleotide binding site [chemical binding]; other site
209261009442	Maf-like protein; Region: Maf; pfam02545
209261009443	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
209261009444	active site
209261009445	dimer interface [polypeptide binding]; other site
209261009446	rod shape-determining protein MreD; Provisional; Region: PRK11060
209261009447	rod shape-determining protein MreC; Region: mreC; TIGR00219
209261009448	rod shape-determining protein MreC; Region: MreC; pfam04085
209261009449	rod shape-determining protein MreB; Provisional; Region: PRK13927
209261009450	MreB and similar proteins; Region: MreB_like; cd10225
209261009451	nucleotide binding site [chemical binding]; other site
209261009452	Mg binding site [ion binding]; other site
209261009453	putative protofilament interaction site [polypeptide binding]; other site
209261009454	RodZ interaction site [polypeptide binding]; other site
209261009455	regulatory protein CsrD; Provisional; Region: PRK11059
209261009456	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
209261009457	metal binding site [ion binding]; metal-binding site
209261009458	active site
209261009459	I-site; other site
209261009460	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261009461	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
209261009462	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
209261009463	NADP binding site [chemical binding]; other site
209261009464	dimer interface [polypeptide binding]; other site
209261009465	TMAO/DMSO reductase; Reviewed; Region: PRK05363
209261009466	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
209261009467	Moco binding site; other site
209261009468	metal coordination site [ion binding]; other site
209261009469	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
209261009470	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
209261009471	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
209261009472	carboxyltransferase (CT) interaction site; other site
209261009473	biotinylation site [posttranslational modification]; other site
209261009474	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
209261009475	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
209261009476	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
209261009477	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
209261009478	hypothetical protein; Provisional; Region: PRK10633
209261009479	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
209261009480	Na binding site [ion binding]; other site
209261009481	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
209261009482	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
209261009483	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
209261009484	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
209261009485	FMN binding site [chemical binding]; other site
209261009486	active site
209261009487	catalytic residues [active]
209261009488	substrate binding site [chemical binding]; other site
209261009489	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
209261009490	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
209261009491	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
209261009492	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261009493	DNA methylase; Region: N6_N4_Mtase; pfam01555
209261009494	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
209261009495	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
209261009496	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
209261009497	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
209261009498	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
209261009499	metal binding site [ion binding]; metal-binding site
209261009500	active site
209261009501	I-site; other site
209261009502	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261009503	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
209261009504	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
209261009505	potassium transporter; Provisional; Region: PRK10750
209261009506	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
209261009507	hypothetical protein; Provisional; Region: PRK11568
209261009508	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
209261009509	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
209261009510	proline dipeptidase; Provisional; Region: PRK13607
209261009511	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
209261009512	active site
209261009513	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
209261009514	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
209261009515	substrate binding site [chemical binding]; other site
209261009516	oxyanion hole (OAH) forming residues; other site
209261009517	trimer interface [polypeptide binding]; other site
209261009518	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
209261009519	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
209261009520	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
209261009521	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
209261009522	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
209261009523	dimer interface [polypeptide binding]; other site
209261009524	active site
209261009525	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
209261009526	FMN reductase; Validated; Region: fre; PRK08051
209261009527	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
209261009528	FAD binding pocket [chemical binding]; other site
209261009529	FAD binding motif [chemical binding]; other site
209261009530	phosphate binding motif [ion binding]; other site
209261009531	beta-alpha-beta structure motif; other site
209261009532	NAD binding pocket [chemical binding]; other site
209261009533	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
209261009534	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
209261009535	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
209261009536	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
209261009537	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
209261009538	active site
209261009539	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
209261009540	sec-independent translocase; Provisional; Region: PRK01770
209261009541	sec-independent translocase; Provisional; Region: tatB; PRK00404
209261009542	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
209261009543	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
209261009544	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
209261009545	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
209261009546	SCP-2 sterol transfer family; Region: SCP2; pfam02036
209261009547	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
209261009548	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261009549	S-adenosylmethionine binding site [chemical binding]; other site
209261009550	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
209261009551	DNA recombination protein RmuC; Provisional; Region: PRK10361
209261009552	RmuC family; Region: RmuC; pfam02646
209261009553	uridine phosphorylase; Provisional; Region: PRK11178
209261009554	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
209261009555	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
209261009556	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
209261009557	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261009558	FeS/SAM binding site; other site
209261009559	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
209261009560	SEC-C motif; Region: SEC-C; pfam02810
209261009561	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
209261009562	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
209261009563	THF binding site; other site
209261009564	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
209261009565	substrate binding site [chemical binding]; other site
209261009566	THF binding site; other site
209261009567	zinc-binding site [ion binding]; other site
209261009568	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
209261009569	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261009570	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
209261009571	putative dimerization interface [polypeptide binding]; other site
209261009572	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
209261009573	EamA-like transporter family; Region: EamA; pfam00892
209261009574	putative hydrolase; Provisional; Region: PRK10976
209261009575	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261009576	active site
209261009577	motif I; other site
209261009578	motif II; other site
209261009579	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261009580	lysophospholipase L2; Provisional; Region: PRK10749
209261009581	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
209261009582	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
209261009583	threonine efflux system; Provisional; Region: PRK10229
209261009584	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
209261009585	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261009586	ATP binding site [chemical binding]; other site
209261009587	putative Mg++ binding site [ion binding]; other site
209261009588	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261009589	nucleotide binding region [chemical binding]; other site
209261009590	ATP-binding site [chemical binding]; other site
209261009591	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
209261009592	Helicase and RNase D C-terminal; Region: HRDC; smart00341
209261009593	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
209261009594	dimerization interface [polypeptide binding]; other site
209261009595	substrate binding site [chemical binding]; other site
209261009596	active site
209261009597	calcium binding site [ion binding]; other site
209261009598	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
209261009599	CoenzymeA binding site [chemical binding]; other site
209261009600	subunit interaction site [polypeptide binding]; other site
209261009601	PHB binding site; other site
209261009602	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
209261009603	EamA-like transporter family; Region: EamA; cl17759
209261009604	hypothetical protein; Provisional; Region: PRK11371
209261009605	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
209261009606	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
209261009607	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
209261009608	Cl binding site [ion binding]; other site
209261009609	oligomer interface [polypeptide binding]; other site
209261009610	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
209261009611	Part of AAA domain; Region: AAA_19; pfam13245
209261009612	Family description; Region: UvrD_C_2; pfam13538
209261009613	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
209261009614	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261009615	motif II; other site
209261009616	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
209261009617	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
209261009618	active site
209261009619	Int/Topo IB signature motif; other site
209261009620	hypothetical protein; Provisional; Region: PRK10963
209261009621	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
209261009622	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
209261009623	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
209261009624	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
209261009625	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
209261009626	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
209261009627	putative iron binding site [ion binding]; other site
209261009628	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
209261009629	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
209261009630	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
209261009631	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
209261009632	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
209261009633	domain interfaces; other site
209261009634	active site
209261009635	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
209261009636	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
209261009637	active site
209261009638	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
209261009639	HemX; Region: HemX; pfam04375
209261009640	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
209261009641	HemY protein N-terminus; Region: HemY_N; pfam07219
209261009642	putative transport protein YifK; Provisional; Region: PRK10746
209261009643	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
209261009644	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
209261009645	putative common antigen polymerase; Provisional; Region: PRK02975
209261009646	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
209261009647	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
209261009648	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
209261009649	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
209261009650	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
209261009651	inhibitor-cofactor binding pocket; inhibition site
209261009652	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261009653	catalytic residue [active]
209261009654	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
209261009655	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
209261009656	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
209261009657	substrate binding site; other site
209261009658	tetramer interface; other site
209261009659	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
209261009660	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
209261009661	NAD binding site [chemical binding]; other site
209261009662	substrate binding site [chemical binding]; other site
209261009663	homodimer interface [polypeptide binding]; other site
209261009664	active site
209261009665	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
209261009666	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
209261009667	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
209261009668	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
209261009669	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
209261009670	active site
209261009671	homodimer interface [polypeptide binding]; other site
209261009672	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
209261009673	Chain length determinant protein; Region: Wzz; pfam02706
209261009674	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
209261009675	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
209261009676	Mg++ binding site [ion binding]; other site
209261009677	putative catalytic motif [active]
209261009678	substrate binding site [chemical binding]; other site
209261009679	transcription termination factor Rho; Provisional; Region: rho; PRK09376
209261009680	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
209261009681	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
209261009682	RNA binding site [nucleotide binding]; other site
209261009683	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
209261009684	multimer interface [polypeptide binding]; other site
209261009685	Walker A motif; other site
209261009686	ATP binding site [chemical binding]; other site
209261009687	Walker B motif; other site
209261009688	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
209261009689	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
209261009690	catalytic residues [active]
209261009691	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
209261009692	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
209261009693	ATP binding site [chemical binding]; other site
209261009694	Mg++ binding site [ion binding]; other site
209261009695	motif III; other site
209261009696	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261009697	nucleotide binding region [chemical binding]; other site
209261009698	ATP-binding site [chemical binding]; other site
209261009699	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
209261009700	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
209261009701	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
209261009702	Part of AAA domain; Region: AAA_19; pfam13245
209261009703	Family description; Region: UvrD_C_2; pfam13538
209261009704	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
209261009705	uridine phosphorylase; Provisional; Region: PRK11178
209261009706	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
209261009707	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
209261009708	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
209261009709	ligand binding site [chemical binding]; other site
209261009710	flexible hinge region; other site
209261009711	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
209261009712	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
209261009713	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
209261009714	ketol-acid reductoisomerase; Validated; Region: PRK05225
209261009715	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
209261009716	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
209261009717	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
209261009718	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261009719	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
209261009720	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
209261009721	putative dimerization interface [polypeptide binding]; other site
209261009722	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
209261009723	Phage-related protein [Function unknown]; Region: COG4679
209261009724	threonine dehydratase; Reviewed; Region: PRK09224
209261009725	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
209261009726	tetramer interface [polypeptide binding]; other site
209261009727	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261009728	catalytic residue [active]
209261009729	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
209261009730	putative Ile/Val binding site [chemical binding]; other site
209261009731	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
209261009732	putative Ile/Val binding site [chemical binding]; other site
209261009733	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
209261009734	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
209261009735	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
209261009736	homodimer interface [polypeptide binding]; other site
209261009737	substrate-cofactor binding pocket; other site
209261009738	catalytic residue [active]
209261009739	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
209261009740	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
209261009741	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
209261009742	PYR/PP interface [polypeptide binding]; other site
209261009743	dimer interface [polypeptide binding]; other site
209261009744	TPP binding site [chemical binding]; other site
209261009745	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
209261009746	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
209261009747	TPP-binding site [chemical binding]; other site
209261009748	dimer interface [polypeptide binding]; other site
209261009749	ilvG operon leader peptide; Provisional; Region: PRK10424
209261009750	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
209261009751	integrase; Provisional; Region: int; PHA02601
209261009752	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
209261009753	active site
209261009754	DNA binding site [nucleotide binding]
209261009755	Int/Topo IB signature motif; other site
209261009756	Predicted transcriptional regulator [Transcription]; Region: COG2932
209261009757	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
209261009758	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
209261009759	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
209261009760	DksA-like zinc finger domain containing protein; Region: PHA00080
209261009761	DNA adenine methylase (dam); Region: dam; TIGR00571
209261009762	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
209261009763	The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p; Region: HIRAN; smart00910
209261009764	portal vertex protein; Provisional; Region: Q; PHA02536
209261009765	Phage portal protein; Region: Phage_portal; pfam04860
209261009766	terminase ATPase subunit; Provisional; Region: P; PHA02535
209261009767	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
209261009768	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
209261009769	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
209261009770	capsid protein; Provisional; Region: N; PHA02538
209261009771	terminase endonuclease subunit; Provisional; Region: M; PHA02537
209261009772	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
209261009773	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
209261009774	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
209261009775	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
209261009776	catalytic residues [active]
209261009777	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
209261009778	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
209261009779	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
209261009780	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
209261009781	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
209261009782	baseplate wedge subunit; Provisional; Region: W; PHA02516
209261009783	baseplate assembly protein; Provisional; Region: J; PHA02568
209261009784	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
209261009785	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
209261009786	Phage Tail Collar Domain; Region: Collar; pfam07484
209261009787	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
209261009788	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
209261009789	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
209261009790	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
209261009791	catalytic residues [active]
209261009792	catalytic nucleophile [active]
209261009793	Presynaptic Site I dimer interface [polypeptide binding]; other site
209261009794	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
209261009795	Synaptic Flat tetramer interface [polypeptide binding]; other site
209261009796	Synaptic Site I dimer interface [polypeptide binding]; other site
209261009797	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
209261009798	DNA-binding interface [nucleotide binding]; DNA binding site
209261009799	major tail sheath protein; Provisional; Region: FI; PHA02560
209261009800	major tail tube protein; Provisional; Region: FII; PHA02600
209261009801	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
209261009802	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
209261009803	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
209261009804	Phage protein U [General function prediction only]; Region: COG3499
209261009805	tail protein; Provisional; Region: D; PHA02561
209261009806	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
209261009807	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
209261009808	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
209261009809	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261009810	Walker A motif; other site
209261009811	ATP binding site [chemical binding]; other site
209261009812	Walker B motif; other site
209261009813	arginine finger; other site
209261009814	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
209261009815	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261009816	hypothetical protein; Provisional; Region: PRK11027
209261009817	transcriptional regulator HdfR; Provisional; Region: PRK03601
209261009818	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261009819	LysR substrate binding domain; Region: LysR_substrate; pfam03466
209261009820	dimerization interface [polypeptide binding]; other site
209261009821	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
209261009822	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
209261009823	purine monophosphate binding site [chemical binding]; other site
209261009824	dimer interface [polypeptide binding]; other site
209261009825	putative catalytic residues [active]
209261009826	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
209261009827	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
209261009828	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
209261009829	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
209261009830	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
209261009831	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
209261009832	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261009833	active site
209261009834	phosphorylation site [posttranslational modification]
209261009835	intermolecular recognition site; other site
209261009836	dimerization interface [polypeptide binding]; other site
209261009837	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261009838	Walker A motif; other site
209261009839	ATP binding site [chemical binding]; other site
209261009840	Walker B motif; other site
209261009841	arginine finger; other site
209261009842	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
209261009843	sensor protein ZraS; Provisional; Region: PRK10364
209261009844	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261009845	dimer interface [polypeptide binding]; other site
209261009846	phosphorylation site [posttranslational modification]
209261009847	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261009848	ATP binding site [chemical binding]; other site
209261009849	Mg2+ binding site [ion binding]; other site
209261009850	G-X-G motif; other site
209261009851	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
209261009852	dimer interface [polypeptide binding]; other site
209261009853	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
209261009854	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
209261009855	IHF dimer interface [polypeptide binding]; other site
209261009856	IHF - DNA interface [nucleotide binding]; other site
209261009857	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
209261009858	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
209261009859	Active_site [active]
209261009860	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
209261009861	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
209261009862	substrate binding site [chemical binding]; other site
209261009863	active site
209261009864	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
209261009865	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
209261009866	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
209261009867	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
209261009868	putative NADH binding site [chemical binding]; other site
209261009869	putative active site [active]
209261009870	nudix motif; other site
209261009871	putative metal binding site [ion binding]; other site
209261009872	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
209261009873	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
209261009874	ThiC-associated domain; Region: ThiC-associated; pfam13667
209261009875	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
209261009876	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
209261009877	thiamine phosphate binding site [chemical binding]; other site
209261009878	active site
209261009879	pyrophosphate binding site [ion binding]; other site
209261009880	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
209261009881	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
209261009882	ATP binding site [chemical binding]; other site
209261009883	substrate interface [chemical binding]; other site
209261009884	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
209261009885	thiS-thiF/thiG interaction site; other site
209261009886	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
209261009887	ThiS interaction site; other site
209261009888	putative active site [active]
209261009889	tetramer interface [polypeptide binding]; other site
209261009890	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
209261009891	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261009892	FeS/SAM binding site; other site
209261009893	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
209261009894	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
209261009895	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
209261009896	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
209261009897	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
209261009898	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
209261009899	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
209261009900	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
209261009901	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
209261009902	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
209261009903	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
209261009904	DNA binding site [nucleotide binding]
209261009905	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
209261009906	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
209261009907	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
209261009908	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
209261009909	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
209261009910	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
209261009911	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
209261009912	RPB3 interaction site [polypeptide binding]; other site
209261009913	RPB1 interaction site [polypeptide binding]; other site
209261009914	RPB11 interaction site [polypeptide binding]; other site
209261009915	RPB10 interaction site [polypeptide binding]; other site
209261009916	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
209261009917	core dimer interface [polypeptide binding]; other site
209261009918	peripheral dimer interface [polypeptide binding]; other site
209261009919	L10 interface [polypeptide binding]; other site
209261009920	L11 interface [polypeptide binding]; other site
209261009921	putative EF-Tu interaction site [polypeptide binding]; other site
209261009922	putative EF-G interaction site [polypeptide binding]; other site
209261009923	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
209261009924	23S rRNA interface [nucleotide binding]; other site
209261009925	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
209261009926	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
209261009927	mRNA/rRNA interface [nucleotide binding]; other site
209261009928	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
209261009929	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
209261009930	23S rRNA interface [nucleotide binding]; other site
209261009931	L7/L12 interface [polypeptide binding]; other site
209261009932	putative thiostrepton binding site; other site
209261009933	L25 interface [polypeptide binding]; other site
209261009934	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
209261009935	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
209261009936	putative homodimer interface [polypeptide binding]; other site
209261009937	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
209261009938	heterodimer interface [polypeptide binding]; other site
209261009939	homodimer interface [polypeptide binding]; other site
209261009940	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
209261009941	elongation factor Tu; Reviewed; Region: PRK00049
209261009942	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
209261009943	G1 box; other site
209261009944	GEF interaction site [polypeptide binding]; other site
209261009945	GTP/Mg2+ binding site [chemical binding]; other site
209261009946	Switch I region; other site
209261009947	G2 box; other site
209261009948	G3 box; other site
209261009949	Switch II region; other site
209261009950	G4 box; other site
209261009951	G5 box; other site
209261009952	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
209261009953	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
209261009954	Antibiotic Binding Site [chemical binding]; other site
209261009955	pantothenate kinase; Provisional; Region: PRK05439
209261009956	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
209261009957	ATP-binding site [chemical binding]; other site
209261009958	CoA-binding site [chemical binding]; other site
209261009959	Mg2+-binding site [ion binding]; other site
209261009960	Biotin operon repressor [Transcription]; Region: BirA; COG1654
209261009961	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
209261009962	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
209261009963	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
209261009964	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
209261009965	FAD binding domain; Region: FAD_binding_4; pfam01565
209261009966	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
209261009967	glutamate racemase; Provisional; Region: PRK00865
209261009968	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
209261009969	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
209261009970	N-terminal plug; other site
209261009971	ligand-binding site [chemical binding]; other site
209261009972	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
209261009973	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
209261009974	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261009975	S-adenosylmethionine binding site [chemical binding]; other site
209261009976	hypothetical protein; Provisional; Region: PRK11056
209261009977	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
209261009978	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261009979	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
209261009980	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261009981	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
209261009982	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
209261009983	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261009984	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
209261009985	dimerization interface [polypeptide binding]; other site
209261009986	argininosuccinate lyase; Provisional; Region: PRK04833
209261009987	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
209261009988	active sites [active]
209261009989	tetramer interface [polypeptide binding]; other site
209261009990	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
209261009991	nucleotide binding site [chemical binding]; other site
209261009992	N-acetyl-L-glutamate binding site [chemical binding]; other site
209261009993	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
209261009994	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
209261009995	acetylornithine deacetylase; Provisional; Region: PRK05111
209261009996	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
209261009997	metal binding site [ion binding]; metal-binding site
209261009998	putative dimer interface [polypeptide binding]; other site
209261009999	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
209261010000	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
209261010001	hypothetical protein; Provisional; Region: PRK10649
209261010002	Sulfatase; Region: Sulfatase; pfam00884
209261010003	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
209261010004	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261010005	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
209261010006	active site
209261010007	intersubunit interactions; other site
209261010008	catalytic residue [active]
209261010009	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
209261010010	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
209261010011	dimer interface [polypeptide binding]; other site
209261010012	active site
209261010013	metal binding site [ion binding]; metal-binding site
209261010014	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
209261010015	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
209261010016	heme binding site [chemical binding]; other site
209261010017	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
209261010018	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
209261010019	FAD binding site [chemical binding]; other site
209261010020	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
209261010021	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261010022	DNA-binding site [nucleotide binding]; DNA binding site
209261010023	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261010024	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261010025	homodimer interface [polypeptide binding]; other site
209261010026	catalytic residue [active]
209261010027	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
209261010028	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
209261010029	active site
209261010030	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
209261010031	dimer interface [polypeptide binding]; other site
209261010032	substrate binding site [chemical binding]; other site
209261010033	catalytic residues [active]
209261010034	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
209261010035	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
209261010036	dimer interface [polypeptide binding]; other site
209261010037	active site
209261010038	glycine-pyridoxal phosphate binding site [chemical binding]; other site
209261010039	folate binding site [chemical binding]; other site
209261010040	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
209261010041	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
209261010042	active site
209261010043	metal binding site [ion binding]; metal-binding site
209261010044	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
209261010045	Insertion element protein; Region: Ins_element1; pfam03811
209261010046	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
209261010047	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
209261010048	putative catalytic residues [active]
209261010049	putative nucleotide binding site [chemical binding]; other site
209261010050	putative aspartate binding site [chemical binding]; other site
209261010051	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
209261010052	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
209261010053	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
209261010054	cystathionine gamma-synthase; Provisional; Region: PRK08045
209261010055	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
209261010056	homodimer interface [polypeptide binding]; other site
209261010057	substrate-cofactor binding pocket; other site
209261010058	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261010059	catalytic residue [active]
209261010060	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
209261010061	dimerization interface [polypeptide binding]; other site
209261010062	DNA binding site [nucleotide binding]
209261010063	corepressor binding sites; other site
209261010064	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
209261010065	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
209261010066	primosome assembly protein PriA; Validated; Region: PRK05580
209261010067	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261010068	ATP binding site [chemical binding]; other site
209261010069	putative Mg++ binding site [ion binding]; other site
209261010070	helicase superfamily c-terminal domain; Region: HELICc; smart00490
209261010071	ATP-binding site [chemical binding]; other site
209261010072	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261010073	DNA binding site [nucleotide binding]
209261010074	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
209261010075	domain linker motif; other site
209261010076	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
209261010077	dimerization interface [polypeptide binding]; other site
209261010078	ligand binding site [chemical binding]; other site
209261010079	essential cell division protein FtsN; Provisional; Region: PRK10927
209261010080	cell division protein FtsN; Provisional; Region: PRK12757
209261010081	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
209261010082	active site
209261010083	HslU subunit interaction site [polypeptide binding]; other site
209261010084	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
209261010085	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261010086	Walker A motif; other site
209261010087	ATP binding site [chemical binding]; other site
209261010088	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
209261010089	Walker B motif; other site
209261010090	arginine finger; other site
209261010091	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
209261010092	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
209261010093	UbiA prenyltransferase family; Region: UbiA; pfam01040
209261010094	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
209261010095	septal ring assembly protein ZapB; Provisional; Region: PRK15422
209261010096	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
209261010097	amphipathic channel; other site
209261010098	Asn-Pro-Ala signature motifs; other site
209261010099	glycerol kinase; Provisional; Region: glpK; PRK00047
209261010100	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
209261010101	N- and C-terminal domain interface [polypeptide binding]; other site
209261010102	active site
209261010103	MgATP binding site [chemical binding]; other site
209261010104	catalytic site [active]
209261010105	metal binding site [ion binding]; metal-binding site
209261010106	glycerol binding site [chemical binding]; other site
209261010107	homotetramer interface [polypeptide binding]; other site
209261010108	homodimer interface [polypeptide binding]; other site
209261010109	FBP binding site [chemical binding]; other site
209261010110	protein IIAGlc interface [polypeptide binding]; other site
209261010111	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
209261010112	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
209261010113	putative active site [active]
209261010114	ferredoxin-NADP reductase; Provisional; Region: PRK10926
209261010115	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
209261010116	FAD binding pocket [chemical binding]; other site
209261010117	FAD binding motif [chemical binding]; other site
209261010118	phosphate binding motif [ion binding]; other site
209261010119	beta-alpha-beta structure motif; other site
209261010120	NAD binding pocket [chemical binding]; other site
209261010121	Predicted membrane protein [Function unknown]; Region: COG3152
209261010122	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
209261010123	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
209261010124	triosephosphate isomerase; Provisional; Region: PRK14567
209261010125	substrate binding site [chemical binding]; other site
209261010126	dimer interface [polypeptide binding]; other site
209261010127	catalytic triad [active]
209261010128	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
209261010129	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
209261010130	substrate binding site [chemical binding]; other site
209261010131	hexamer interface [polypeptide binding]; other site
209261010132	metal binding site [ion binding]; metal-binding site
209261010133	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
209261010134	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
209261010135	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
209261010136	putative active site; other site
209261010137	catalytic residue [active]
209261010138	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
209261010139	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
209261010140	ligand binding site [chemical binding]; other site
209261010141	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
209261010142	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
209261010143	TM-ABC transporter signature motif; other site
209261010144	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
209261010145	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
209261010146	TM-ABC transporter signature motif; other site
209261010147	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
209261010148	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
209261010149	Walker A/P-loop; other site
209261010150	ATP binding site [chemical binding]; other site
209261010151	Q-loop/lid; other site
209261010152	ABC transporter signature motif; other site
209261010153	Walker B; other site
209261010154	D-loop; other site
209261010155	H-loop/switch region; other site
209261010156	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
209261010157	transcriptional regulator LsrR; Provisional; Region: PRK15418
209261010158	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
209261010159	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
209261010160	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
209261010161	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
209261010162	putative N- and C-terminal domain interface [polypeptide binding]; other site
209261010163	putative active site [active]
209261010164	putative MgATP binding site [chemical binding]; other site
209261010165	catalytic site [active]
209261010166	metal binding site [ion binding]; metal-binding site
209261010167	putative carbohydrate binding site [chemical binding]; other site
209261010168	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
209261010169	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
209261010170	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
209261010171	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261010172	DNA-binding site [nucleotide binding]; DNA binding site
209261010173	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
209261010174	UTRA domain; Region: UTRA; pfam07702
209261010175	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
209261010176	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
209261010177	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
209261010178	putative substrate binding site [chemical binding]; other site
209261010179	putative ATP binding site [chemical binding]; other site
209261010180	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
209261010181	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
209261010182	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261010183	substrate binding pocket [chemical binding]; other site
209261010184	membrane-bound complex binding site; other site
209261010185	hinge residues; other site
209261010186	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
209261010187	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
209261010188	active site
209261010189	ADP/pyrophosphate binding site [chemical binding]; other site
209261010190	dimerization interface [polypeptide binding]; other site
209261010191	allosteric effector site; other site
209261010192	fructose-1,6-bisphosphate binding site; other site
209261010193	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
209261010194	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
209261010195	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
209261010196	dimer interface [polypeptide binding]; other site
209261010197	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
209261010198	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261010199	active site
209261010200	intermolecular recognition site; other site
209261010201	dimerization interface [polypeptide binding]; other site
209261010202	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261010203	DNA binding site [nucleotide binding]
209261010204	two-component sensor protein; Provisional; Region: cpxA; PRK09470
209261010205	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261010206	dimerization interface [polypeptide binding]; other site
209261010207	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261010208	dimer interface [polypeptide binding]; other site
209261010209	phosphorylation site [posttranslational modification]
209261010210	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261010211	ATP binding site [chemical binding]; other site
209261010212	Mg2+ binding site [ion binding]; other site
209261010213	G-X-G motif; other site
209261010214	SnoaL-like domain; Region: SnoaL_2; pfam12680
209261010215	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
209261010216	MOSC domain; Region: MOSC; pfam03473
209261010217	3-alpha domain; Region: 3-alpha; pfam03475
209261010218	superoxide dismutase; Provisional; Region: PRK10925
209261010219	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
209261010220	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
209261010221	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
209261010222	DctM-like transporters; Region: DctM; pfam06808
209261010223	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
209261010224	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
209261010225	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
209261010226	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
209261010227	transcriptional activator RhaR; Provisional; Region: PRK13502
209261010228	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
209261010229	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261010230	transcriptional activator RhaS; Provisional; Region: PRK13503
209261010231	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
209261010232	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261010233	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261010234	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
209261010235	N- and C-terminal domain interface [polypeptide binding]; other site
209261010236	active site
209261010237	putative catalytic site [active]
209261010238	metal binding site [ion binding]; metal-binding site
209261010239	ATP binding site [chemical binding]; other site
209261010240	rhamnulokinase; Provisional; Region: rhaB; PRK10640
209261010241	carbohydrate binding site [chemical binding]; other site
209261010242	L-rhamnose isomerase; Provisional; Region: PRK01076
209261010243	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
209261010244	lactaldehyde reductase; Region: lactal_redase; TIGR02638
209261010245	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
209261010246	dimer interface [polypeptide binding]; other site
209261010247	active site
209261010248	metal binding site [ion binding]; metal-binding site
209261010249	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
209261010250	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
209261010251	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261010252	non-specific DNA binding site [nucleotide binding]; other site
209261010253	salt bridge; other site
209261010254	sequence-specific DNA binding site [nucleotide binding]; other site
209261010255	Cupin domain; Region: Cupin_2; cl17218
209261010256	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
209261010257	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
209261010258	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
209261010259	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
209261010260	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
209261010261	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
209261010262	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
209261010263	[4Fe-4S] binding site [ion binding]; other site
209261010264	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
209261010265	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
209261010266	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
209261010267	molybdopterin cofactor binding site; other site
209261010268	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
209261010269	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
209261010270	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
209261010271	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
209261010272	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
209261010273	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
209261010274	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
209261010275	oligomeric interface; other site
209261010276	putative active site [active]
209261010277	homodimer interface [polypeptide binding]; other site
209261010278	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
209261010279	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
209261010280	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
209261010281	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
209261010282	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261010283	non-specific DNA binding site [nucleotide binding]; other site
209261010284	salt bridge; other site
209261010285	sequence-specific DNA binding site [nucleotide binding]; other site
209261010286	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261010287	Coenzyme A binding pocket [chemical binding]; other site
209261010288	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
209261010289	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
209261010290	putative active site [active]
209261010291	dimerization interface [polypeptide binding]; other site
209261010292	putative tRNAtyr binding site [nucleotide binding]; other site
209261010293	hypothetical protein; Reviewed; Region: PRK01637
209261010294	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
209261010295	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261010296	motif II; other site
209261010297	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
209261010298	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
209261010299	putative DNA binding site [nucleotide binding]; other site
209261010300	putative Zn2+ binding site [ion binding]; other site
209261010301	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261010302	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
209261010303	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
209261010304	substrate binding site [chemical binding]; other site
209261010305	ATP binding site [chemical binding]; other site
209261010306	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
209261010307	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
209261010308	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
209261010309	putative aldose-1-epimerase; Provisional; Region: PRK15172
209261010310	active site
209261010311	catalytic residues [active]
209261010312	alpha-glucosidase; Provisional; Region: PRK10426
209261010313	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
209261010314	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
209261010315	putative active site [active]
209261010316	putative catalytic site [active]
209261010317	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
209261010318	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
209261010319	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
209261010320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261010321	putative substrate translocation pore; other site
209261010322	outer membrane porin L; Provisional; Region: ompL; PRK09980
209261010323	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
209261010324	Leucine-rich repeats; other site
209261010325	Substrate binding site [chemical binding]; other site
209261010326	Sulfatase; Region: Sulfatase; cl17466
209261010327	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261010328	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
209261010329	active site
209261010330	motif I; other site
209261010331	motif II; other site
209261010332	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261010333	GTP-binding protein; Provisional; Region: PRK10218
209261010334	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
209261010335	G1 box; other site
209261010336	putative GEF interaction site [polypeptide binding]; other site
209261010337	GTP/Mg2+ binding site [chemical binding]; other site
209261010338	Switch I region; other site
209261010339	G2 box; other site
209261010340	G3 box; other site
209261010341	Switch II region; other site
209261010342	G4 box; other site
209261010343	G5 box; other site
209261010344	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
209261010345	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
209261010346	glutamine synthetase; Provisional; Region: glnA; PRK09469
209261010347	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
209261010348	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
209261010349	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
209261010350	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
209261010351	putative active site [active]
209261010352	heme pocket [chemical binding]; other site
209261010353	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261010354	dimer interface [polypeptide binding]; other site
209261010355	phosphorylation site [posttranslational modification]
209261010356	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261010357	ATP binding site [chemical binding]; other site
209261010358	Mg2+ binding site [ion binding]; other site
209261010359	G-X-G motif; other site
209261010360	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
209261010361	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261010362	active site
209261010363	phosphorylation site [posttranslational modification]
209261010364	intermolecular recognition site; other site
209261010365	dimerization interface [polypeptide binding]; other site
209261010366	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261010367	Walker A motif; other site
209261010368	ATP binding site [chemical binding]; other site
209261010369	Walker B motif; other site
209261010370	arginine finger; other site
209261010371	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
209261010372	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
209261010373	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261010374	FeS/SAM binding site; other site
209261010375	HemN C-terminal domain; Region: HemN_C; pfam06969
209261010376	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
209261010377	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
209261010378	G1 box; other site
209261010379	GTP/Mg2+ binding site [chemical binding]; other site
209261010380	Switch I region; other site
209261010381	G2 box; other site
209261010382	G3 box; other site
209261010383	Switch II region; other site
209261010384	G4 box; other site
209261010385	G5 box; other site
209261010386	DNA polymerase I; Provisional; Region: PRK05755
209261010387	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
209261010388	active site
209261010389	metal binding site 1 [ion binding]; metal-binding site
209261010390	putative 5' ssDNA interaction site; other site
209261010391	metal binding site 3; metal-binding site
209261010392	metal binding site 2 [ion binding]; metal-binding site
209261010393	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
209261010394	putative DNA binding site [nucleotide binding]; other site
209261010395	putative metal binding site [ion binding]; other site
209261010396	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
209261010397	active site
209261010398	catalytic site [active]
209261010399	substrate binding site [chemical binding]; other site
209261010400	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
209261010401	active site
209261010402	DNA binding site [nucleotide binding]
209261010403	catalytic site [active]
209261010404	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
209261010405	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
209261010406	putative acyl-acceptor binding pocket; other site
209261010407	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
209261010408	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
209261010409	catalytic residues [active]
209261010410	hinge region; other site
209261010411	alpha helical domain; other site
209261010412	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
209261010413	serine/threonine protein kinase; Provisional; Region: PRK11768
209261010414	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
209261010415	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
209261010416	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
209261010417	GTP binding site; other site
209261010418	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
209261010419	Walker A motif; other site
209261010420	Transcriptional regulators [Transcription]; Region: FadR; COG2186
209261010421	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261010422	DNA-binding site [nucleotide binding]; DNA binding site
209261010423	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
209261010424	transcriptional repressor RbsR; Provisional; Region: PRK10423
209261010425	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261010426	DNA binding site [nucleotide binding]
209261010427	domain linker motif; other site
209261010428	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
209261010429	dimerization interface [polypeptide binding]; other site
209261010430	ligand binding site [chemical binding]; other site
209261010431	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
209261010432	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
209261010433	substrate binding site [chemical binding]; other site
209261010434	dimer interface [polypeptide binding]; other site
209261010435	ATP binding site [chemical binding]; other site
209261010436	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
209261010437	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
209261010438	ligand binding site [chemical binding]; other site
209261010439	dimerization interface [polypeptide binding]; other site
209261010440	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
209261010441	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
209261010442	TM-ABC transporter signature motif; other site
209261010443	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
209261010444	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
209261010445	Walker A/P-loop; other site
209261010446	ATP binding site [chemical binding]; other site
209261010447	Q-loop/lid; other site
209261010448	ABC transporter signature motif; other site
209261010449	Walker B; other site
209261010450	D-loop; other site
209261010451	H-loop/switch region; other site
209261010452	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
209261010453	D-ribose pyranase; Provisional; Region: PRK11797
209261010454	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
209261010455	potassium uptake protein; Region: kup; TIGR00794
209261010456	regulatory ATPase RavA; Provisional; Region: PRK13531
209261010457	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261010458	Walker A motif; other site
209261010459	ATP binding site [chemical binding]; other site
209261010460	Walker B motif; other site
209261010461	arginine finger; other site
209261010462	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
209261010463	hypothetical protein; Provisional; Region: yieM; PRK10997
209261010464	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
209261010465	metal ion-dependent adhesion site (MIDAS); other site
209261010466	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
209261010467	dimer interface [polypeptide binding]; other site
209261010468	active site
209261010469	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
209261010470	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
209261010471	putative DNA binding site [nucleotide binding]; other site
209261010472	putative Zn2+ binding site [ion binding]; other site
209261010473	AsnC family; Region: AsnC_trans_reg; pfam01037
209261010474	FMN-binding protein MioC; Provisional; Region: PRK09004
209261010475	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
209261010476	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
209261010477	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
209261010478	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
209261010479	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261010480	S-adenosylmethionine binding site [chemical binding]; other site
209261010481	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
209261010482	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
209261010483	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
209261010484	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
209261010485	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
209261010486	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
209261010487	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
209261010488	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
209261010489	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
209261010490	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
209261010491	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
209261010492	beta subunit interaction interface [polypeptide binding]; other site
209261010493	Walker A motif; other site
209261010494	ATP binding site [chemical binding]; other site
209261010495	Walker B motif; other site
209261010496	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
209261010497	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
209261010498	core domain interface [polypeptide binding]; other site
209261010499	delta subunit interface [polypeptide binding]; other site
209261010500	epsilon subunit interface [polypeptide binding]; other site
209261010501	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
209261010502	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
209261010503	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
209261010504	alpha subunit interaction interface [polypeptide binding]; other site
209261010505	Walker A motif; other site
209261010506	ATP binding site [chemical binding]; other site
209261010507	Walker B motif; other site
209261010508	inhibitor binding site; inhibition site
209261010509	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
209261010510	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
209261010511	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
209261010512	gamma subunit interface [polypeptide binding]; other site
209261010513	epsilon subunit interface [polypeptide binding]; other site
209261010514	LBP interface [polypeptide binding]; other site
209261010515	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
209261010516	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
209261010517	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
209261010518	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
209261010519	Substrate binding site; other site
209261010520	Mg++ binding site; other site
209261010521	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
209261010522	active site
209261010523	substrate binding site [chemical binding]; other site
209261010524	CoA binding site [chemical binding]; other site
209261010525	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
209261010526	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
209261010527	glutaminase active site [active]
209261010528	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
209261010529	dimer interface [polypeptide binding]; other site
209261010530	active site
209261010531	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
209261010532	dimer interface [polypeptide binding]; other site
209261010533	active site
209261010534	fimbrial protein; Provisional; Region: lpfA; PRK15289
209261010535	fimbrial chaperone protein; Provisional; Region: lfpB; PRK15290
209261010536	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261010537	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261010538	fimbrial protein StgD; Provisional; Region: PRK15291
209261010539	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
209261010540	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
209261010541	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
209261010542	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
209261010543	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
209261010544	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
209261010545	shikimate binding site; other site
209261010546	NAD(P) binding site [chemical binding]; other site
209261010547	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
209261010548	active site
209261010549	P-loop; other site
209261010550	phosphorylation site [posttranslational modification]
209261010551	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
209261010552	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
209261010553	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261010554	substrate binding pocket [chemical binding]; other site
209261010555	membrane-bound complex binding site; other site
209261010556	hinge residues; other site
209261010557	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
209261010558	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261010559	dimer interface [polypeptide binding]; other site
209261010560	conserved gate region; other site
209261010561	putative PBP binding loops; other site
209261010562	ABC-ATPase subunit interface; other site
209261010563	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
209261010564	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261010565	dimer interface [polypeptide binding]; other site
209261010566	conserved gate region; other site
209261010567	putative PBP binding loops; other site
209261010568	ABC-ATPase subunit interface; other site
209261010569	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
209261010570	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
209261010571	Walker A/P-loop; other site
209261010572	ATP binding site [chemical binding]; other site
209261010573	Q-loop/lid; other site
209261010574	ABC transporter signature motif; other site
209261010575	Walker B; other site
209261010576	D-loop; other site
209261010577	H-loop/switch region; other site
209261010578	transcriptional regulator PhoU; Provisional; Region: PRK11115
209261010579	PhoU domain; Region: PhoU; pfam01895
209261010580	PhoU domain; Region: PhoU; pfam01895
209261010581	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
209261010582	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261010583	active site
209261010584	motif I; other site
209261010585	motif II; other site
209261010586	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
209261010587	Predicted flavoprotein [General function prediction only]; Region: COG0431
209261010588	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
209261010589	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
209261010590	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
209261010591	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261010592	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
209261010593	substrate binding pocket [chemical binding]; other site
209261010594	dimerization interface [polypeptide binding]; other site
209261010595	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
209261010596	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261010597	putative substrate translocation pore; other site
209261010598	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
209261010599	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
209261010600	trmE is a tRNA modification GTPase; Region: trmE; cd04164
209261010601	G1 box; other site
209261010602	GTP/Mg2+ binding site [chemical binding]; other site
209261010603	Switch I region; other site
209261010604	G2 box; other site
209261010605	Switch II region; other site
209261010606	G3 box; other site
209261010607	G4 box; other site
209261010608	G5 box; other site
209261010609	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
209261010610	membrane protein insertase; Provisional; Region: PRK01318
209261010611	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
209261010612	ribonuclease P; Reviewed; Region: rnpA; PRK01732
209261010613	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
209261010614	DnaA N-terminal domain; Region: DnaA_N; pfam11638
209261010615	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
209261010616	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261010617	Walker A motif; other site
209261010618	ATP binding site [chemical binding]; other site
209261010619	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
209261010620	Walker B motif; other site
209261010621	arginine finger; other site
209261010622	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
209261010623	DnaA box-binding interface [nucleotide binding]; other site
209261010624	DNA polymerase III subunit beta; Validated; Region: PRK05643
209261010625	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
209261010626	putative DNA binding surface [nucleotide binding]; other site
209261010627	dimer interface [polypeptide binding]; other site
209261010628	beta-clamp/clamp loader binding surface; other site
209261010629	beta-clamp/translesion DNA polymerase binding surface; other site
209261010630	recF protein; Region: recf; TIGR00611
209261010631	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261010632	Walker A/P-loop; other site
209261010633	ATP binding site [chemical binding]; other site
209261010634	Q-loop/lid; other site
209261010635	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261010636	ABC transporter signature motif; other site
209261010637	Walker B; other site
209261010638	D-loop; other site
209261010639	H-loop/switch region; other site
209261010640	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
209261010641	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261010642	Mg2+ binding site [ion binding]; other site
209261010643	G-X-G motif; other site
209261010644	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
209261010645	anchoring element; other site
209261010646	dimer interface [polypeptide binding]; other site
209261010647	ATP binding site [chemical binding]; other site
209261010648	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
209261010649	active site
209261010650	putative metal-binding site [ion binding]; other site
209261010651	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
209261010652	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261010653	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261010654	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
209261010655	putative dimerization interface [polypeptide binding]; other site
209261010656	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
209261010657	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
209261010658	active site pocket [active]
209261010659	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261010660	D-galactonate transporter; Region: 2A0114; TIGR00893
209261010661	putative substrate translocation pore; other site
209261010662	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261010663	sugar phosphate phosphatase; Provisional; Region: PRK10513
209261010664	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261010665	active site
209261010666	motif I; other site
209261010667	motif II; other site
209261010668	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261010669	Surface antigen; Region: Bac_surface_Ag; pfam01103
209261010670	Protein of unknown function (DUF4056); Region: DUF4056; pfam13265
209261010671	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
209261010672	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261010673	dimer interface [polypeptide binding]; other site
209261010674	phosphorylation site [posttranslational modification]
209261010675	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261010676	ATP binding site [chemical binding]; other site
209261010677	Mg2+ binding site [ion binding]; other site
209261010678	G-X-G motif; other site
209261010679	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261010680	active site
209261010681	phosphorylation site [posttranslational modification]
209261010682	intermolecular recognition site; other site
209261010683	dimerization interface [polypeptide binding]; other site
209261010684	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
209261010685	putative binding surface; other site
209261010686	active site
209261010687	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
209261010688	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
209261010689	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
209261010690	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
209261010691	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
209261010692	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
209261010693	molybdopterin cofactor binding site [chemical binding]; other site
209261010694	substrate binding site [chemical binding]; other site
209261010695	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
209261010696	molybdopterin cofactor binding site; other site
209261010697	chaperone protein TorD; Validated; Region: torD; PRK04976
209261010698	Haem-binding domain; Region: Haem_bd; pfam14376
209261010699	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
209261010700	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
209261010701	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261010702	Walker A/P-loop; other site
209261010703	ATP binding site [chemical binding]; other site
209261010704	Q-loop/lid; other site
209261010705	ABC transporter signature motif; other site
209261010706	Walker B; other site
209261010707	D-loop; other site
209261010708	H-loop/switch region; other site
209261010709	ABC-type transport system involved in cytochrome c biogenesis, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CcmB; COG2386
209261010710	heme exporter protein CcmC; Region: ccmC; TIGR01191
209261010711	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
209261010712	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
209261010713	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
209261010714	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
209261010715	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
209261010716	catalytic residues [active]
209261010717	central insert; other site
209261010718	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
209261010719	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
209261010720	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
209261010721	hypothetical protein; Provisional; Region: PRK11616
209261010722	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
209261010723	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
209261010724	putative dimer interface [polypeptide binding]; other site
209261010725	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
209261010726	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
209261010727	putative dimer interface [polypeptide binding]; other site
209261010728	putative transporter; Validated; Region: PRK03818
209261010729	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
209261010730	TrkA-C domain; Region: TrkA_C; pfam02080
209261010731	TrkA-C domain; Region: TrkA_C; pfam02080
209261010732	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
209261010733	Domain of unknown function (DUF202); Region: DUF202; pfam02656
209261010734	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
209261010735	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
209261010736	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
209261010737	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
209261010738	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
209261010739	catalytic residue [active]
209261010740	permease DsdX; Provisional; Region: PRK09921
209261010741	gluconate transporter; Region: gntP; TIGR00791
209261010742	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
209261010743	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261010744	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
209261010745	dimerization interface [polypeptide binding]; other site
209261010746	substrate binding pocket [chemical binding]; other site
209261010747	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
209261010748	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
209261010749	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261010750	putative substrate translocation pore; other site
209261010751	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
209261010752	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
209261010753	PYR/PP interface [polypeptide binding]; other site
209261010754	dimer interface [polypeptide binding]; other site
209261010755	TPP binding site [chemical binding]; other site
209261010756	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
209261010757	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
209261010758	TPP-binding site [chemical binding]; other site
209261010759	dimer interface [polypeptide binding]; other site
209261010760	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
209261010761	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
209261010762	putative valine binding site [chemical binding]; other site
209261010763	dimer interface [polypeptide binding]; other site
209261010764	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
209261010765	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
209261010766	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261010767	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
209261010768	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
209261010769	substrate binding site [chemical binding]; other site
209261010770	dimer interface [polypeptide binding]; other site
209261010771	ATP binding site [chemical binding]; other site
209261010772	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
209261010773	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261010774	putative substrate translocation pore; other site
209261010775	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
209261010776	active site
209261010777	catalytic residues [active]
209261010778	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
209261010779	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261010780	active site
209261010781	phosphorylation site [posttranslational modification]
209261010782	intermolecular recognition site; other site
209261010783	dimerization interface [polypeptide binding]; other site
209261010784	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261010785	DNA binding residues [nucleotide binding]
209261010786	dimerization interface [polypeptide binding]; other site
209261010787	sensory histidine kinase UhpB; Provisional; Region: PRK11644
209261010788	MASE1; Region: MASE1; pfam05231
209261010789	Histidine kinase; Region: HisKA_3; pfam07730
209261010790	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261010791	ATP binding site [chemical binding]; other site
209261010792	Mg2+ binding site [ion binding]; other site
209261010793	G-X-G motif; other site
209261010794	regulatory protein UhpC; Provisional; Region: PRK11663
209261010795	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261010796	putative substrate translocation pore; other site
209261010797	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
209261010798	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261010799	putative substrate translocation pore; other site
209261010800	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
209261010801	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
209261010802	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261010803	DNA-binding site [nucleotide binding]; DNA binding site
209261010804	UTRA domain; Region: UTRA; pfam07702
209261010805	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
209261010806	active site
209261010807	phosphorylation site [posttranslational modification]
209261010808	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
209261010809	active site
209261010810	P-loop; other site
209261010811	phosphorylation site [posttranslational modification]
209261010812	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
209261010813	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
209261010814	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
209261010815	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
209261010816	putative N- and C-terminal domain interface [polypeptide binding]; other site
209261010817	putative active site [active]
209261010818	putative MgATP binding site [chemical binding]; other site
209261010819	catalytic site [active]
209261010820	metal binding site [ion binding]; metal-binding site
209261010821	putative carbohydrate binding site [chemical binding]; other site
209261010822	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
209261010823	dimerization domain swap beta strand [polypeptide binding]; other site
209261010824	regulatory protein interface [polypeptide binding]; other site
209261010825	active site
209261010826	regulatory phosphorylation site [posttranslational modification]; other site
209261010827	Predicted transcriptional regulator [Transcription]; Region: COG2944
209261010828	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261010829	non-specific DNA binding site [nucleotide binding]; other site
209261010830	salt bridge; other site
209261010831	sequence-specific DNA binding site [nucleotide binding]; other site
209261010832	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
209261010833	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261010834	putative substrate translocation pore; other site
209261010835	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
209261010836	beta-galactosidase; Region: BGL; TIGR03356
209261010837	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
209261010838	active pocket/dimerization site; other site
209261010839	active site
209261010840	phosphorylation site [posttranslational modification]
209261010841	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
209261010842	active site
209261010843	phosphorylation site [posttranslational modification]
209261010844	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
209261010845	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
209261010846	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
209261010847	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
209261010848	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
209261010849	hypothetical protein; Provisional; Region: PRK09956
209261010850	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
209261010851	EamA-like transporter family; Region: EamA; pfam00892
209261010852	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
209261010853	EamA-like transporter family; Region: EamA; pfam00892
209261010854	magnesium transport protein MgtC; Provisional; Region: PRK15385
209261010855	MgtC family; Region: MgtC; pfam02308
209261010856	magnesium-transporting ATPase; Provisional; Region: PRK15122
209261010857	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
209261010858	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
209261010859	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
209261010860	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
209261010861	Soluble P-type ATPase [General function prediction only]; Region: COG4087
209261010862	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
209261010863	Isochorismatase family; Region: Isochorismatase; pfam00857
209261010864	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
209261010865	catalytic triad [active]
209261010866	dimer interface [polypeptide binding]; other site
209261010867	conserved cis-peptide bond; other site
209261010868	Virulence protein [General function prediction only]; Region: COG3943
209261010869	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
209261010870	TIGR02646 family protein; Region: TIGR02646
209261010871	putative transporter; Provisional; Region: PRK11462
209261010872	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
209261010873	putative alpha-glucosidase; Provisional; Region: PRK10658
209261010874	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
209261010875	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
209261010876	active site
209261010877	homotrimer interface [polypeptide binding]; other site
209261010878	catalytic site [active]
209261010879	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
209261010880	AsmA family; Region: AsmA; pfam05170
209261010881	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
209261010882	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
209261010883	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
209261010884	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
209261010885	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
209261010886	generic binding surface II; other site
209261010887	ssDNA binding site; other site
209261010888	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261010889	ATP binding site [chemical binding]; other site
209261010890	putative Mg++ binding site [ion binding]; other site
209261010891	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261010892	nucleotide binding region [chemical binding]; other site
209261010893	ATP-binding site [chemical binding]; other site
209261010894	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
209261010895	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
209261010896	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
209261010897	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
209261010898	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
209261010899	Zn2+ binding site [ion binding]; other site
209261010900	Mg2+ binding site [ion binding]; other site
209261010901	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
209261010902	synthetase active site [active]
209261010903	NTP binding site [chemical binding]; other site
209261010904	metal binding site [ion binding]; metal-binding site
209261010905	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
209261010906	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
209261010907	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
209261010908	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
209261010909	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
209261010910	catalytic site [active]
209261010911	G-X2-G-X-G-K; other site
209261010912	Predicted membrane protein [Function unknown]; Region: COG2860
209261010913	UPF0126 domain; Region: UPF0126; pfam03458
209261010914	UPF0126 domain; Region: UPF0126; pfam03458
209261010915	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
209261010916	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261010917	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261010918	dimerization interface [polypeptide binding]; other site
209261010919	LysR substrate binding domain; Region: LysR_substrate; pfam03466
209261010920	hypothetical protein; Provisional; Region: PRK11820
209261010921	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
209261010922	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
209261010923	ribonuclease PH; Reviewed; Region: rph; PRK00173
209261010924	Ribonuclease PH; Region: RNase_PH_bact; cd11362
209261010925	hexamer interface [polypeptide binding]; other site
209261010926	active site
209261010927	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
209261010928	active site
209261010929	division inhibitor protein; Provisional; Region: slmA; PRK09480
209261010930	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261010931	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
209261010932	trimer interface [polypeptide binding]; other site
209261010933	active site
209261010934	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
209261010935	Flavoprotein; Region: Flavoprotein; pfam02441
209261010936	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
209261010937	hypothetical protein; Reviewed; Region: PRK00024
209261010938	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
209261010939	MPN+ (JAMM) motif; other site
209261010940	Zinc-binding site [ion binding]; other site
209261010941	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
209261010942	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
209261010943	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
209261010944	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
209261010945	DNA binding site [nucleotide binding]
209261010946	catalytic residue [active]
209261010947	H2TH interface [polypeptide binding]; other site
209261010948	putative catalytic residues [active]
209261010949	turnover-facilitating residue; other site
209261010950	intercalation triad [nucleotide binding]; other site
209261010951	8OG recognition residue [nucleotide binding]; other site
209261010952	putative reading head residues; other site
209261010953	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
209261010954	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
209261010955	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
209261010956	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
209261010957	active site
209261010958	(T/H)XGH motif; other site
209261010959	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
209261010960	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
209261010961	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
209261010962	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
209261010963	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
209261010964	putative active site [active]
209261010965	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
209261010966	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
209261010967	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
209261010968	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
209261010969	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
209261010970	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
209261010971	putative ADP-binding pocket [chemical binding]; other site
209261010972	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
209261010973	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
209261010974	Ligand binding site; other site
209261010975	metal-binding site
209261010976	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
209261010977	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
209261010978	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
209261010979	Ligand binding site; other site
209261010980	metal-binding site
209261010981	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
209261010982	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
209261010983	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
209261010984	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
209261010985	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
209261010986	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
209261010987	O-antigen ligase RfaL; Provisional; Region: PRK15487
209261010988	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
209261010989	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
209261010990	putative active site [active]
209261010991	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
209261010992	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
209261010993	putative active site [active]
209261010994	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
209261010995	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
209261010996	NADP binding site [chemical binding]; other site
209261010997	homopentamer interface [polypeptide binding]; other site
209261010998	substrate binding site [chemical binding]; other site
209261010999	active site
209261011000	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
209261011001	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
209261011002	substrate-cofactor binding pocket; other site
209261011003	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261011004	catalytic residue [active]
209261011005	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
209261011006	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
209261011007	NAD(P) binding site [chemical binding]; other site
209261011008	putative glycosyl transferase; Provisional; Region: PRK10073
209261011009	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
209261011010	active site
209261011011	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
209261011012	NodB motif; other site
209261011013	putative active site [active]
209261011014	putative catalytic site [active]
209261011015	Zn binding site [ion binding]; other site
209261011016	AmiB activator; Provisional; Region: PRK11637
209261011017	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
209261011018	Peptidase family M23; Region: Peptidase_M23; pfam01551
209261011019	phosphoglyceromutase; Provisional; Region: PRK05434
209261011020	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
209261011021	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
209261011022	active site residue [active]
209261011023	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
209261011024	GSH binding site [chemical binding]; other site
209261011025	catalytic residues [active]
209261011026	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
209261011027	SecA binding site; other site
209261011028	Preprotein binding site; other site
209261011029	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
209261011030	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
209261011031	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
209261011032	serine acetyltransferase; Provisional; Region: cysE; PRK11132
209261011033	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
209261011034	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
209261011035	trimer interface [polypeptide binding]; other site
209261011036	active site
209261011037	substrate binding site [chemical binding]; other site
209261011038	CoA binding site [chemical binding]; other site
209261011039	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
209261011040	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
209261011041	active site pocket [active]
209261011042	Transcriptional regulators [Transcription]; Region: PurR; COG1609
209261011043	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261011044	DNA binding site [nucleotide binding]
209261011045	domain linker motif; other site
209261011046	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
209261011047	putative dimerization interface [polypeptide binding]; other site
209261011048	putative ligand binding site [chemical binding]; other site
209261011049	putative rRNA methylase; Provisional; Region: PRK10358
209261011050	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
209261011051	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
209261011052	active site
209261011053	substrate binding site [chemical binding]; other site
209261011054	FMN binding site [chemical binding]; other site
209261011055	putative catalytic residues [active]
209261011056	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
209261011057	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261011058	DNA-binding site [nucleotide binding]; DNA binding site
209261011059	FCD domain; Region: FCD; pfam07729
209261011060	L-lactate permease; Provisional; Region: PRK10420
209261011061	glycolate transporter; Provisional; Region: PRK09695
209261011062	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
209261011063	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
209261011064	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
209261011065	Haemagglutinin; Region: HIM; pfam05662
209261011066	Haemagglutinin; Region: HIM; pfam05662
209261011067	YadA-like C-terminal region; Region: YadA; pfam03895
209261011068	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
209261011069	hypothetical protein; Provisional; Region: PRK11020
209261011070	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
209261011071	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
209261011072	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
209261011073	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
209261011074	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
209261011075	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
209261011076	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
209261011077	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
209261011078	active site
209261011079	P-loop; other site
209261011080	phosphorylation site [posttranslational modification]
209261011081	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
209261011082	active site
209261011083	phosphorylation site [posttranslational modification]
209261011084	putative glutathione S-transferase; Provisional; Region: PRK10357
209261011085	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
209261011086	putative C-terminal domain interface [polypeptide binding]; other site
209261011087	putative GSH binding site (G-site) [chemical binding]; other site
209261011088	putative dimer interface [polypeptide binding]; other site
209261011089	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
209261011090	dimer interface [polypeptide binding]; other site
209261011091	N-terminal domain interface [polypeptide binding]; other site
209261011092	putative substrate binding pocket (H-site) [chemical binding]; other site
209261011093	selenocysteine synthase; Provisional; Region: PRK04311
209261011094	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
209261011095	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
209261011096	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
209261011097	catalytic residue [active]
209261011098	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
209261011099	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
209261011100	G1 box; other site
209261011101	putative GEF interaction site [polypeptide binding]; other site
209261011102	GTP/Mg2+ binding site [chemical binding]; other site
209261011103	Switch I region; other site
209261011104	G2 box; other site
209261011105	G3 box; other site
209261011106	Switch II region; other site
209261011107	G4 box; other site
209261011108	G5 box; other site
209261011109	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
209261011110	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
209261011111	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
209261011112	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
209261011113	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
209261011114	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
209261011115	nucleotide binding site [chemical binding]; other site
209261011116	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
209261011117	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
209261011118	NAD(P) binding site [chemical binding]; other site
209261011119	catalytic residues [active]
209261011120	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
209261011121	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
209261011122	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
209261011123	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
209261011124	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261011125	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
209261011126	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
209261011127	intersubunit interface [polypeptide binding]; other site
209261011128	active site
209261011129	Zn2+ binding site [ion binding]; other site
209261011130	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
209261011131	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
209261011132	AP (apurinic/apyrimidinic) site pocket; other site
209261011133	DNA interaction; other site
209261011134	Metal-binding active site; metal-binding site
209261011135	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
209261011136	active site
209261011137	dimer interface [polypeptide binding]; other site
209261011138	magnesium binding site [ion binding]; other site
209261011139	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
209261011140	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
209261011141	putative N- and C-terminal domain interface [polypeptide binding]; other site
209261011142	putative active site [active]
209261011143	MgATP binding site [chemical binding]; other site
209261011144	catalytic site [active]
209261011145	metal binding site [ion binding]; metal-binding site
209261011146	putative xylulose binding site [chemical binding]; other site
209261011147	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
209261011148	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
209261011149	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
209261011150	DctM-like transporters; Region: DctM; pfam06808
209261011151	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
209261011152	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
209261011153	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
209261011154	Transcriptional regulator [Transcription]; Region: IclR; COG1414
209261011155	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
209261011156	Bacterial transcriptional regulator; Region: IclR; pfam01614
209261011157	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
209261011158	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
209261011159	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261011160	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261011161	homodimer interface [polypeptide binding]; other site
209261011162	catalytic residue [active]
209261011163	alpha-amylase; Reviewed; Region: malS; PRK09505
209261011164	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
209261011165	active site
209261011166	catalytic site [active]
209261011167	hypothetical protein; Provisional; Region: PRK10356
209261011168	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
209261011169	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
209261011170	putative dimerization interface [polypeptide binding]; other site
209261011171	Transcriptional regulators [Transcription]; Region: PurR; COG1609
209261011172	putative ligand binding site [chemical binding]; other site
209261011173	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261011174	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
209261011175	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261011176	xylose isomerase; Provisional; Region: PRK05474
209261011177	xylose isomerase; Region: xylose_isom_A; TIGR02630
209261011178	xylulokinase; Provisional; Region: PRK15027
209261011179	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
209261011180	N- and C-terminal domain interface [polypeptide binding]; other site
209261011181	active site
209261011182	MgATP binding site [chemical binding]; other site
209261011183	catalytic site [active]
209261011184	metal binding site [ion binding]; metal-binding site
209261011185	xylulose binding site [chemical binding]; other site
209261011186	homodimer interface [polypeptide binding]; other site
209261011187	Predicted membrane protein [Function unknown]; Region: COG4682
209261011188	yiaA/B two helix domain; Region: YiaAB; pfam05360
209261011189	yiaA/B two helix domain; Region: YiaAB; pfam05360
209261011190	YsaB-like lipoprotein; Region: YsaB; pfam13983
209261011191	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
209261011192	dimer interface [polypeptide binding]; other site
209261011193	motif 1; other site
209261011194	active site
209261011195	motif 2; other site
209261011196	motif 3; other site
209261011197	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
209261011198	DALR anticodon binding domain; Region: DALR_1; pfam05746
209261011199	Integrase core domain; Region: rve; pfam00665
209261011200	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
209261011201	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261011202	Coenzyme A binding pocket [chemical binding]; other site
209261011203	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
209261011204	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
209261011205	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
209261011206	DNA-binding site [nucleotide binding]; DNA binding site
209261011207	RNA-binding motif; other site
209261011208	Predicted transcriptional regulator [Transcription]; Region: COG2944
209261011209	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261011210	salt bridge; other site
209261011211	non-specific DNA binding site [nucleotide binding]; other site
209261011212	sequence-specific DNA binding site [nucleotide binding]; other site
209261011213	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
209261011214	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
209261011215	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
209261011216	dimerization interface [polypeptide binding]; other site
209261011217	ligand binding site [chemical binding]; other site
209261011218	NADP binding site [chemical binding]; other site
209261011219	catalytic site [active]
209261011220	putative outer membrane lipoprotein; Provisional; Region: PRK10510
209261011221	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
209261011222	ligand binding site [chemical binding]; other site
209261011223	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
209261011224	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
209261011225	molybdopterin cofactor binding site [chemical binding]; other site
209261011226	substrate binding site [chemical binding]; other site
209261011227	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
209261011228	molybdopterin cofactor binding site; other site
209261011229	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261011230	Coenzyme A binding pocket [chemical binding]; other site
209261011231	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
209261011232	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
209261011233	phosphoethanolamine transferase; Provisional; Region: PRK11560
209261011234	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
209261011235	Sulfatase; Region: Sulfatase; pfam00884
209261011236	Transcriptional regulators [Transcription]; Region: PurR; COG1609
209261011237	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261011238	DNA binding site [nucleotide binding]
209261011239	domain linker motif; other site
209261011240	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
209261011241	putative dimerization interface [polypeptide binding]; other site
209261011242	putative ligand binding site [chemical binding]; other site
209261011243	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
209261011244	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
209261011245	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
209261011246	peptide binding site [polypeptide binding]; other site
209261011247	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
209261011248	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261011249	dimer interface [polypeptide binding]; other site
209261011250	conserved gate region; other site
209261011251	putative PBP binding loops; other site
209261011252	ABC-ATPase subunit interface; other site
209261011253	dipeptide transporter; Provisional; Region: PRK10913
209261011254	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
209261011255	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261011256	dimer interface [polypeptide binding]; other site
209261011257	conserved gate region; other site
209261011258	putative PBP binding loops; other site
209261011259	ABC-ATPase subunit interface; other site
209261011260	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
209261011261	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261011262	Walker A/P-loop; other site
209261011263	ATP binding site [chemical binding]; other site
209261011264	Q-loop/lid; other site
209261011265	ABC transporter signature motif; other site
209261011266	Walker B; other site
209261011267	D-loop; other site
209261011268	H-loop/switch region; other site
209261011269	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
209261011270	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
209261011271	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
209261011272	Walker A/P-loop; other site
209261011273	ATP binding site [chemical binding]; other site
209261011274	Q-loop/lid; other site
209261011275	ABC transporter signature motif; other site
209261011276	Walker B; other site
209261011277	D-loop; other site
209261011278	H-loop/switch region; other site
209261011279	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
209261011280	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
209261011281	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
209261011282	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
209261011283	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
209261011284	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
209261011285	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
209261011286	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
209261011287	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
209261011288	cell division protein; Provisional; Region: PRK10037
209261011289	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
209261011290	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
209261011291	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
209261011292	DXD motif; other site
209261011293	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
209261011294	PilZ domain; Region: PilZ; pfam07238
209261011295	cellulose synthase regulator protein; Provisional; Region: PRK11114
209261011296	endo-1,4-D-glucanase; Provisional; Region: PRK11097
209261011297	putative diguanylate cyclase; Provisional; Region: PRK13561
209261011298	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
209261011299	metal binding site [ion binding]; metal-binding site
209261011300	active site
209261011301	I-site; other site
209261011302	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261011303	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
209261011304	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
209261011305	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
209261011306	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
209261011307	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
209261011308	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
209261011309	substrate binding site [chemical binding]; other site
209261011310	ATP binding site [chemical binding]; other site
209261011311	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261011312	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
209261011313	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
209261011314	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261011315	metabolite-proton symporter; Region: 2A0106; TIGR00883
209261011316	putative substrate translocation pore; other site
209261011317	inner membrane protein YhjD; Region: TIGR00766
209261011318	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261011319	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261011320	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
209261011321	putative effector binding pocket; other site
209261011322	putative dimerization interface [polypeptide binding]; other site
209261011323	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
209261011324	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261011325	DNA binding residues [nucleotide binding]
209261011326	dimerization interface [polypeptide binding]; other site
209261011327	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
209261011328	catalytic residue [active]
209261011329	trehalase; Provisional; Region: treF; PRK13270
209261011330	Trehalase; Region: Trehalase; pfam01204
209261011331	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
209261011332	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261011333	DNA-binding site [nucleotide binding]; DNA binding site
209261011334	UTRA domain; Region: UTRA; pfam07702
209261011335	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
209261011336	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
209261011337	putative active site [active]
209261011338	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
209261011339	dimer interface [polypeptide binding]; other site
209261011340	active site
209261011341	glutathione reductase; Validated; Region: PRK06116
209261011342	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
209261011343	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261011344	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
209261011345	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
209261011346	hypothetical protein; Provisional; Region: PRK10215
209261011347	oligopeptidase A; Provisional; Region: PRK10911
209261011348	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
209261011349	active site
209261011350	Zn binding site [ion binding]; other site
209261011351	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261011352	S-adenosylmethionine binding site [chemical binding]; other site
209261011353	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
209261011354	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261011355	putative substrate translocation pore; other site
209261011356	POT family; Region: PTR2; pfam00854
209261011357	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
209261011358	Ligand Binding Site [chemical binding]; other site
209261011359	universal stress protein UspB; Provisional; Region: PRK04960
209261011360	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
209261011361	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
209261011362	Predicted flavoproteins [General function prediction only]; Region: COG2081
209261011363	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
209261011364	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
209261011365	YheO-like PAS domain; Region: PAS_6; pfam08348
209261011366	HTH domain; Region: HTH_22; pfam13309
209261011367	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
209261011368	homotrimer interaction site [polypeptide binding]; other site
209261011369	putative active site [active]
209261011370	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
209261011371	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261011372	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261011373	homodimer interface [polypeptide binding]; other site
209261011374	catalytic residue [active]
209261011375	Major Facilitator Superfamily; Region: MFS_1; pfam07690
209261011376	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261011377	HlyD family secretion protein; Region: HlyD; pfam00529
209261011378	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
209261011379	HlyD family secretion protein; Region: HlyD_3; pfam13437
209261011380	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
209261011381	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
209261011382	Walker A/P-loop; other site
209261011383	ATP binding site [chemical binding]; other site
209261011384	Q-loop/lid; other site
209261011385	ABC transporter signature motif; other site
209261011386	Walker B; other site
209261011387	D-loop; other site
209261011388	H-loop/switch region; other site
209261011389	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
209261011390	Walker A/P-loop; other site
209261011391	ATP binding site [chemical binding]; other site
209261011392	Q-loop/lid; other site
209261011393	ABC transporter signature motif; other site
209261011394	Walker B; other site
209261011395	D-loop; other site
209261011396	H-loop/switch region; other site
209261011397	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
209261011398	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
209261011399	nickel responsive regulator; Provisional; Region: PRK02967
209261011400	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
209261011401	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
209261011402	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
209261011403	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
209261011404	Domain of unknown function DUF20; Region: UPF0118; pfam01594
209261011405	major facilitator superfamily transporter; Provisional; Region: PRK05122
209261011406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261011407	putative substrate translocation pore; other site
209261011408	hypothetical protein; Provisional; Region: PRK11615
209261011409	hypothetical protein; Provisional; Region: PRK11212
209261011410	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
209261011411	CPxP  motif; other site
209261011412	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
209261011413	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
209261011414	dimer interface [polypeptide binding]; other site
209261011415	ligand binding site [chemical binding]; other site
209261011416	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261011417	dimerization interface [polypeptide binding]; other site
209261011418	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
209261011419	dimer interface [polypeptide binding]; other site
209261011420	putative CheW interface [polypeptide binding]; other site
209261011421	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
209261011422	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
209261011423	metal-binding site [ion binding]
209261011424	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
209261011425	Predicted membrane protein [Function unknown]; Region: COG3714
209261011426	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
209261011427	hypothetical protein; Provisional; Region: PRK10910
209261011428	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
209261011429	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261011430	S-adenosylmethionine binding site [chemical binding]; other site
209261011431	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
209261011432	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
209261011433	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
209261011434	P loop; other site
209261011435	GTP binding site [chemical binding]; other site
209261011436	cell division protein FtsE; Provisional; Region: PRK10908
209261011437	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261011438	Walker A/P-loop; other site
209261011439	ATP binding site [chemical binding]; other site
209261011440	Q-loop/lid; other site
209261011441	ABC transporter signature motif; other site
209261011442	Walker B; other site
209261011443	D-loop; other site
209261011444	H-loop/switch region; other site
209261011445	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
209261011446	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
209261011447	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
209261011448	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
209261011449	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
209261011450	DNA binding residues [nucleotide binding]
209261011451	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
209261011452	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
209261011453	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
209261011454	dimerization interface [polypeptide binding]; other site
209261011455	ligand binding site [chemical binding]; other site
209261011456	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
209261011457	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
209261011458	TM-ABC transporter signature motif; other site
209261011459	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
209261011460	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
209261011461	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
209261011462	TM-ABC transporter signature motif; other site
209261011463	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
209261011464	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
209261011465	Walker A/P-loop; other site
209261011466	ATP binding site [chemical binding]; other site
209261011467	Q-loop/lid; other site
209261011468	ABC transporter signature motif; other site
209261011469	Walker B; other site
209261011470	D-loop; other site
209261011471	H-loop/switch region; other site
209261011472	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
209261011473	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
209261011474	Walker A/P-loop; other site
209261011475	ATP binding site [chemical binding]; other site
209261011476	Q-loop/lid; other site
209261011477	ABC transporter signature motif; other site
209261011478	Walker B; other site
209261011479	D-loop; other site
209261011480	H-loop/switch region; other site
209261011481	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
209261011482	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
209261011483	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
209261011484	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261011485	dimer interface [polypeptide binding]; other site
209261011486	conserved gate region; other site
209261011487	putative PBP binding loops; other site
209261011488	ABC-ATPase subunit interface; other site
209261011489	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
209261011490	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261011491	dimer interface [polypeptide binding]; other site
209261011492	conserved gate region; other site
209261011493	ABC-ATPase subunit interface; other site
209261011494	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
209261011495	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
209261011496	Walker A/P-loop; other site
209261011497	ATP binding site [chemical binding]; other site
209261011498	Q-loop/lid; other site
209261011499	ABC transporter signature motif; other site
209261011500	Walker B; other site
209261011501	D-loop; other site
209261011502	H-loop/switch region; other site
209261011503	TOBE domain; Region: TOBE_2; pfam08402
209261011504	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
209261011505	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
209261011506	putative active site [active]
209261011507	catalytic site [active]
209261011508	putative metal binding site [ion binding]; other site
209261011509	hypothetical protein; Provisional; Region: PRK10350
209261011510	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
209261011511	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
209261011512	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
209261011513	active site
209261011514	substrate binding pocket [chemical binding]; other site
209261011515	homodimer interaction site [polypeptide binding]; other site
209261011516	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
209261011517	Protein of unknown function, DUF606; Region: DUF606; pfam04657
209261011518	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
209261011519	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
209261011520	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
209261011521	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
209261011522	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
209261011523	substrate binding site [chemical binding]; other site
209261011524	dimer interface [polypeptide binding]; other site
209261011525	ATP binding site [chemical binding]; other site
209261011526	putative acetyltransferase YhhY; Provisional; Region: PRK10140
209261011527	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261011528	Coenzyme A binding pocket [chemical binding]; other site
209261011529	putative oxidoreductase; Provisional; Region: PRK10206
209261011530	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
209261011531	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
209261011532	Pirin-related protein [General function prediction only]; Region: COG1741
209261011533	Pirin; Region: Pirin; pfam02678
209261011534	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
209261011535	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261011536	DNA binding site [nucleotide binding]
209261011537	domain linker motif; other site
209261011538	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
209261011539	putative ligand binding site [chemical binding]; other site
209261011540	putative dimerization interface [polypeptide binding]; other site
209261011541	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
209261011542	ATP-binding site [chemical binding]; other site
209261011543	Gluconate-6-phosphate binding site [chemical binding]; other site
209261011544	low affinity gluconate transporter; Provisional; Region: PRK10472
209261011545	gluconate transporter; Region: gntP; TIGR00791
209261011546	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
209261011547	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
209261011548	glycogen branching enzyme; Provisional; Region: PRK05402
209261011549	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
209261011550	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
209261011551	active site
209261011552	catalytic site [active]
209261011553	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
209261011554	glycogen debranching enzyme; Provisional; Region: PRK03705
209261011555	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
209261011556	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
209261011557	active site
209261011558	catalytic site [active]
209261011559	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
209261011560	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
209261011561	ligand binding site; other site
209261011562	oligomer interface; other site
209261011563	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
209261011564	dimer interface [polypeptide binding]; other site
209261011565	N-terminal domain interface [polypeptide binding]; other site
209261011566	sulfate 1 binding site; other site
209261011567	glycogen synthase; Provisional; Region: glgA; PRK00654
209261011568	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
209261011569	ADP-binding pocket [chemical binding]; other site
209261011570	homodimer interface [polypeptide binding]; other site
209261011571	glycogen phosphorylase; Provisional; Region: PRK14986
209261011572	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
209261011573	homodimer interface [polypeptide binding]; other site
209261011574	active site pocket [active]
209261011575	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
209261011576	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
209261011577	active site residue [active]
209261011578	intramembrane serine protease GlpG; Provisional; Region: PRK10907
209261011579	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
209261011580	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
209261011581	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
209261011582	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
209261011583	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261011584	transcriptional regulator MalT; Provisional; Region: PRK04841
209261011585	AAA ATPase domain; Region: AAA_16; pfam13191
209261011586	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261011587	DNA binding residues [nucleotide binding]
209261011588	dimerization interface [polypeptide binding]; other site
209261011589	maltodextrin phosphorylase; Provisional; Region: PRK14985
209261011590	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
209261011591	homodimer interface [polypeptide binding]; other site
209261011592	active site pocket [active]
209261011593	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
209261011594	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
209261011595	high-affinity gluconate transporter; Provisional; Region: PRK14984
209261011596	gluconate transporter; Region: gntP; TIGR00791
209261011597	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
209261011598	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
209261011599	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
209261011600	DNA utilization protein GntX; Provisional; Region: PRK11595
209261011601	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
209261011602	active site
209261011603	carboxylesterase BioH; Provisional; Region: PRK10349
209261011604	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
209261011605	hypothetical protein; Provisional; Region: PRK09956
209261011606	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
209261011607	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
209261011608	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
209261011609	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
209261011610	G1 box; other site
209261011611	GTP/Mg2+ binding site [chemical binding]; other site
209261011612	Switch I region; other site
209261011613	G2 box; other site
209261011614	G3 box; other site
209261011615	Switch II region; other site
209261011616	G4 box; other site
209261011617	G5 box; other site
209261011618	Nucleoside recognition; Region: Gate; pfam07670
209261011619	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
209261011620	Nucleoside recognition; Region: Gate; pfam07670
209261011621	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
209261011622	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
209261011623	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
209261011624	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
209261011625	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
209261011626	RNA binding site [nucleotide binding]; other site
209261011627	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
209261011628	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
209261011629	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
209261011630	osmolarity response regulator; Provisional; Region: ompR; PRK09468
209261011631	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261011632	active site
209261011633	phosphorylation site [posttranslational modification]
209261011634	intermolecular recognition site; other site
209261011635	dimerization interface [polypeptide binding]; other site
209261011636	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261011637	DNA binding site [nucleotide binding]
209261011638	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
209261011639	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
209261011640	dimerization interface [polypeptide binding]; other site
209261011641	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261011642	dimer interface [polypeptide binding]; other site
209261011643	phosphorylation site [posttranslational modification]
209261011644	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261011645	ATP binding site [chemical binding]; other site
209261011646	G-X-G motif; other site
209261011647	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
209261011648	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
209261011649	active site
209261011650	substrate-binding site [chemical binding]; other site
209261011651	metal-binding site [ion binding]
209261011652	ATP binding site [chemical binding]; other site
209261011653	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
209261011654	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
209261011655	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
209261011656	dimerization interface [polypeptide binding]; other site
209261011657	domain crossover interface; other site
209261011658	redox-dependent activation switch; other site
209261011659	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
209261011660	RNA binding surface [nucleotide binding]; other site
209261011661	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
209261011662	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261011663	motif II; other site
209261011664	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
209261011665	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
209261011666	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
209261011667	ADP-ribose binding site [chemical binding]; other site
209261011668	dimer interface [polypeptide binding]; other site
209261011669	active site
209261011670	nudix motif; other site
209261011671	metal binding site [ion binding]; metal-binding site
209261011672	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
209261011673	Transglycosylase; Region: Transgly; pfam00912
209261011674	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
209261011675	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
209261011676	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
209261011677	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
209261011678	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
209261011679	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
209261011680	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
209261011681	shikimate kinase; Reviewed; Region: aroK; PRK00131
209261011682	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
209261011683	ADP binding site [chemical binding]; other site
209261011684	magnesium binding site [ion binding]; other site
209261011685	putative shikimate binding site; other site
209261011686	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
209261011687	active site
209261011688	dimer interface [polypeptide binding]; other site
209261011689	metal binding site [ion binding]; metal-binding site
209261011690	cell division protein DamX; Validated; Region: PRK10905
209261011691	DNA adenine methylase; Provisional; Region: PRK10904
209261011692	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
209261011693	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
209261011694	substrate binding site [chemical binding]; other site
209261011695	hexamer interface [polypeptide binding]; other site
209261011696	metal binding site [ion binding]; metal-binding site
209261011697	phosphoglycolate phosphatase; Provisional; Region: PRK13222
209261011698	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261011699	motif II; other site
209261011700	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
209261011701	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
209261011702	active site
209261011703	HIGH motif; other site
209261011704	dimer interface [polypeptide binding]; other site
209261011705	KMSKS motif; other site
209261011706	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
209261011707	siroheme synthase; Provisional; Region: cysG; PRK10637
209261011708	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
209261011709	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
209261011710	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
209261011711	active site
209261011712	SAM binding site [chemical binding]; other site
209261011713	homodimer interface [polypeptide binding]; other site
209261011714	nitrite transporter NirC; Provisional; Region: PRK11562
209261011715	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
209261011716	nitrite reductase subunit NirD; Provisional; Region: PRK14989
209261011717	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
209261011718	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
209261011719	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
209261011720	putative transporter; Provisional; Region: PRK03699
209261011721	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261011722	putative substrate translocation pore; other site
209261011723	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
209261011724	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
209261011725	substrate binding site [chemical binding]; other site
209261011726	hypothetical protein; Provisional; Region: PRK10204
209261011727	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
209261011728	cell filamentation protein Fic; Provisional; Region: PRK10347
209261011729	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
209261011730	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
209261011731	glutamine binding [chemical binding]; other site
209261011732	catalytic triad [active]
209261011733	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
209261011734	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
209261011735	inhibitor-cofactor binding pocket; inhibition site
209261011736	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261011737	catalytic residue [active]
209261011738	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
209261011739	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
209261011740	ligand binding site [chemical binding]; other site
209261011741	flexible hinge region; other site
209261011742	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
209261011743	putative switch regulator; other site
209261011744	non-specific DNA interactions [nucleotide binding]; other site
209261011745	DNA binding site [nucleotide binding]
209261011746	sequence specific DNA binding site [nucleotide binding]; other site
209261011747	putative cAMP binding site [chemical binding]; other site
209261011748	hypothetical protein; Provisional; Region: PRK10738
209261011749	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
209261011750	active site
209261011751	hypothetical protein; Provisional; Region: PRK04966
209261011752	putative monooxygenase; Provisional; Region: PRK11118
209261011753	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
209261011754	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261011755	Walker A/P-loop; other site
209261011756	ATP binding site [chemical binding]; other site
209261011757	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
209261011758	ABC transporter signature motif; other site
209261011759	Walker B; other site
209261011760	D-loop; other site
209261011761	ABC transporter; Region: ABC_tran_2; pfam12848
209261011762	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
209261011763	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
209261011764	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
209261011765	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
209261011766	TrkA-N domain; Region: TrkA_N; pfam02254
209261011767	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
209261011768	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
209261011769	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
209261011770	phi X174 lysis protein; Provisional; Region: PRK02793
209261011771	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
209261011772	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
209261011773	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
209261011774	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
209261011775	YheO-like PAS domain; Region: PAS_6; pfam08348
209261011776	HTH domain; Region: HTH_22; pfam13309
209261011777	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
209261011778	sulfur relay protein TusC; Validated; Region: PRK00211
209261011779	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
209261011780	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
209261011781	S17 interaction site [polypeptide binding]; other site
209261011782	S8 interaction site; other site
209261011783	16S rRNA interaction site [nucleotide binding]; other site
209261011784	streptomycin interaction site [chemical binding]; other site
209261011785	23S rRNA interaction site [nucleotide binding]; other site
209261011786	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
209261011787	30S ribosomal protein S7; Validated; Region: PRK05302
209261011788	elongation factor G; Reviewed; Region: PRK00007
209261011789	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
209261011790	G1 box; other site
209261011791	putative GEF interaction site [polypeptide binding]; other site
209261011792	GTP/Mg2+ binding site [chemical binding]; other site
209261011793	Switch I region; other site
209261011794	G2 box; other site
209261011795	G3 box; other site
209261011796	Switch II region; other site
209261011797	G4 box; other site
209261011798	G5 box; other site
209261011799	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
209261011800	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
209261011801	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
209261011802	elongation factor Tu; Reviewed; Region: PRK00049
209261011803	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
209261011804	G1 box; other site
209261011805	GEF interaction site [polypeptide binding]; other site
209261011806	GTP/Mg2+ binding site [chemical binding]; other site
209261011807	Switch I region; other site
209261011808	G2 box; other site
209261011809	G3 box; other site
209261011810	Switch II region; other site
209261011811	G4 box; other site
209261011812	G5 box; other site
209261011813	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
209261011814	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
209261011815	Antibiotic Binding Site [chemical binding]; other site
209261011816	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
209261011817	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
209261011818	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
209261011819	heme binding site [chemical binding]; other site
209261011820	ferroxidase pore; other site
209261011821	ferroxidase diiron center [ion binding]; other site
209261011822	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
209261011823	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
209261011824	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
209261011825	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
209261011826	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
209261011827	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
209261011828	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
209261011829	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
209261011830	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
209261011831	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
209261011832	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
209261011833	protein-rRNA interface [nucleotide binding]; other site
209261011834	putative translocon binding site; other site
209261011835	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
209261011836	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
209261011837	G-X-X-G motif; other site
209261011838	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
209261011839	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
209261011840	23S rRNA interface [nucleotide binding]; other site
209261011841	5S rRNA interface [nucleotide binding]; other site
209261011842	putative antibiotic binding site [chemical binding]; other site
209261011843	L25 interface [polypeptide binding]; other site
209261011844	L27 interface [polypeptide binding]; other site
209261011845	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
209261011846	23S rRNA interface [nucleotide binding]; other site
209261011847	putative translocon interaction site; other site
209261011848	signal recognition particle (SRP54) interaction site; other site
209261011849	L23 interface [polypeptide binding]; other site
209261011850	trigger factor interaction site; other site
209261011851	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
209261011852	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
209261011853	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
209261011854	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
209261011855	RNA binding site [nucleotide binding]; other site
209261011856	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
209261011857	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
209261011858	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
209261011859	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
209261011860	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
209261011861	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
209261011862	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
209261011863	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
209261011864	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
209261011865	23S rRNA interface [nucleotide binding]; other site
209261011866	5S rRNA interface [nucleotide binding]; other site
209261011867	L27 interface [polypeptide binding]; other site
209261011868	L5 interface [polypeptide binding]; other site
209261011869	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
209261011870	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
209261011871	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
209261011872	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
209261011873	23S rRNA binding site [nucleotide binding]; other site
209261011874	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
209261011875	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
209261011876	SecY translocase; Region: SecY; pfam00344
209261011877	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
209261011878	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
209261011879	30S ribosomal protein S13; Region: bact_S13; TIGR03631
209261011880	30S ribosomal protein S11; Validated; Region: PRK05309
209261011881	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
209261011882	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
209261011883	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
209261011884	RNA binding surface [nucleotide binding]; other site
209261011885	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
209261011886	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
209261011887	alphaNTD homodimer interface [polypeptide binding]; other site
209261011888	alphaNTD - beta interaction site [polypeptide binding]; other site
209261011889	alphaNTD - beta' interaction site [polypeptide binding]; other site
209261011890	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
209261011891	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
209261011892	hypothetical protein; Provisional; Region: PRK10203
209261011893	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
209261011894	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
209261011895	DNA binding residues [nucleotide binding]
209261011896	dimer interface [polypeptide binding]; other site
209261011897	metal binding site [ion binding]; metal-binding site
209261011898	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
209261011899	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
209261011900	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
209261011901	TrkA-N domain; Region: TrkA_N; pfam02254
209261011902	TrkA-C domain; Region: TrkA_C; pfam02080
209261011903	TrkA-N domain; Region: TrkA_N; pfam02254
209261011904	TrkA-C domain; Region: TrkA_C; pfam02080
209261011905	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
209261011906	putative RNA binding site [nucleotide binding]; other site
209261011907	16S rRNA methyltransferase B; Provisional; Region: PRK10901
209261011908	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261011909	S-adenosylmethionine binding site [chemical binding]; other site
209261011910	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
209261011911	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
209261011912	putative active site [active]
209261011913	substrate binding site [chemical binding]; other site
209261011914	putative cosubstrate binding site; other site
209261011915	catalytic site [active]
209261011916	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
209261011917	substrate binding site [chemical binding]; other site
209261011918	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
209261011919	active site
209261011920	catalytic residues [active]
209261011921	metal binding site [ion binding]; metal-binding site
209261011922	hypothetical protein; Provisional; Region: PRK10736
209261011923	DNA protecting protein DprA; Region: dprA; TIGR00732
209261011924	hypothetical protein; Validated; Region: PRK03430
209261011925	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
209261011926	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
209261011927	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
209261011928	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
209261011929	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
209261011930	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
209261011931	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
209261011932	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
209261011933	shikimate binding site; other site
209261011934	NAD(P) binding site [chemical binding]; other site
209261011935	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
209261011936	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
209261011937	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
209261011938	trimer interface [polypeptide binding]; other site
209261011939	putative metal binding site [ion binding]; other site
209261011940	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
209261011941	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261011942	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
209261011943	Coenzyme A binding pocket [chemical binding]; other site
209261011944	homoserine O-succinyltransferase; Provisional; Region: PRK05368
209261011945	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
209261011946	proposed active site lysine [active]
209261011947	conserved cys residue [active]
209261011948	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
209261011949	malate synthase A; Region: malate_syn_A; TIGR01344
209261011950	active site
209261011951	isocitrate lyase; Provisional; Region: PRK15063
209261011952	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
209261011953	tetramer interface [polypeptide binding]; other site
209261011954	active site
209261011955	Mg2+/Mn2+ binding site [ion binding]; other site
209261011956	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
209261011957	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
209261011958	transcriptional repressor IclR; Provisional; Region: PRK11569
209261011959	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
209261011960	Bacterial transcriptional regulator; Region: IclR; pfam01614
209261011961	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
209261011962	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
209261011963	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
209261011964	substrate binding pocket [chemical binding]; other site
209261011965	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
209261011966	B12 binding site [chemical binding]; other site
209261011967	cobalt ligand [ion binding]; other site
209261011968	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
209261011969	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
209261011970	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
209261011971	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
209261011972	active site pocket [active]
209261011973	oxyanion hole [active]
209261011974	catalytic triad [active]
209261011975	active site nucleophile [active]
209261011976	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
209261011977	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
209261011978	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
209261011979	RNA binding surface [nucleotide binding]; other site
209261011980	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
209261011981	probable active site [active]
209261011982	hypothetical protein; Provisional; Region: PRK10515
209261011983	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
209261011984	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
209261011985	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261011986	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
209261011987	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
209261011988	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
209261011989	active site
209261011990	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
209261011991	phosphate binding site [ion binding]; other site
209261011992	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
209261011993	aspartate kinase III; Validated; Region: PRK09084
209261011994	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
209261011995	nucleotide binding site [chemical binding]; other site
209261011996	substrate binding site [chemical binding]; other site
209261011997	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
209261011998	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
209261011999	dimer interface [polypeptide binding]; other site
209261012000	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
209261012001	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
209261012002	active site
209261012003	dimer interface [polypeptide binding]; other site
209261012004	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
209261012005	dimer interface [polypeptide binding]; other site
209261012006	active site
209261012007	Exopolysaccharide production protein YjbE; Region: YjbE; pfam11106
209261012008	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
209261012009	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
209261012010	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
209261012011	Predicted membrane protein [Function unknown]; Region: COG3223
209261012012	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
209261012013	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261012014	dimer interface [polypeptide binding]; other site
209261012015	conserved gate region; other site
209261012016	putative PBP binding loops; other site
209261012017	ABC-ATPase subunit interface; other site
209261012018	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
209261012019	dimer interface [polypeptide binding]; other site
209261012020	conserved gate region; other site
209261012021	putative PBP binding loops; other site
209261012022	ABC-ATPase subunit interface; other site
209261012023	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
209261012024	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
209261012025	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
209261012026	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
209261012027	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
209261012028	Walker A/P-loop; other site
209261012029	ATP binding site [chemical binding]; other site
209261012030	Q-loop/lid; other site
209261012031	ABC transporter signature motif; other site
209261012032	Walker B; other site
209261012033	D-loop; other site
209261012034	H-loop/switch region; other site
209261012035	TOBE domain; Region: TOBE_2; pfam08402
209261012036	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
209261012037	trimer interface; other site
209261012038	sugar binding site [chemical binding]; other site
209261012039	maltose regulon periplasmic protein; Provisional; Region: PRK10564
209261012040	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
209261012041	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
209261012042	UbiA prenyltransferase family; Region: UbiA; pfam01040
209261012043	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
209261012044	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
209261012045	putative acyl-acceptor binding pocket; other site
209261012046	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
209261012047	LexA repressor; Validated; Region: PRK00215
209261012048	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
209261012049	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
209261012050	Catalytic site [active]
209261012051	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
209261012052	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
209261012053	hypothetical protein; Provisional; Region: PRK10428
209261012054	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
209261012055	metal binding site 2 [ion binding]; metal-binding site
209261012056	putative DNA binding helix; other site
209261012057	metal binding site 1 [ion binding]; metal-binding site
209261012058	dimer interface [polypeptide binding]; other site
209261012059	structural Zn2+ binding site [ion binding]; other site
209261012060	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
209261012061	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
209261012062	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
209261012063	FMN binding site [chemical binding]; other site
209261012064	active site
209261012065	catalytic residues [active]
209261012066	substrate binding site [chemical binding]; other site
209261012067	phage shock protein G; Reviewed; Region: pspG; PRK09459
209261012068	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
209261012069	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
209261012070	NADP binding site [chemical binding]; other site
209261012071	dimer interface [polypeptide binding]; other site
209261012072	replicative DNA helicase; Provisional; Region: PRK08006
209261012073	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
209261012074	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
209261012075	Walker A motif; other site
209261012076	ATP binding site [chemical binding]; other site
209261012077	Walker B motif; other site
209261012078	DNA binding loops [nucleotide binding]
209261012079	alanine racemase; Reviewed; Region: alr; PRK00053
209261012080	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
209261012081	active site
209261012082	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
209261012083	substrate binding site [chemical binding]; other site
209261012084	catalytic residues [active]
209261012085	dimer interface [polypeptide binding]; other site
209261012086	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
209261012087	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
209261012088	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261012089	homodimer interface [polypeptide binding]; other site
209261012090	catalytic residue [active]
209261012091	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261012092	active site
209261012093	motif I; other site
209261012094	motif II; other site
209261012095	Uncharacterized conserved protein [Function unknown]; Region: COG0432
209261012096	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
209261012097	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
209261012098	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
209261012099	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
209261012100	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
209261012101	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
209261012102	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
209261012103	dimer interface [polypeptide binding]; other site
209261012104	ssDNA binding site [nucleotide binding]; other site
209261012105	tetramer (dimer of dimers) interface [polypeptide binding]; other site
209261012106	hypothetical protein; Validated; Region: PRK09039
209261012107	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
209261012108	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
209261012109	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
209261012110	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
209261012111	HlyD family secretion protein; Region: HlyD_3; pfam13437
209261012112	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012113	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012114	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012115	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012116	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
209261012117	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
209261012118	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012119	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
209261012120	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
209261012121	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012122	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
209261012123	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
209261012124	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012125	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
209261012126	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
209261012127	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012128	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
209261012129	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012130	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
209261012131	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
209261012132	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012133	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
209261012134	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012135	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
209261012136	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012137	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012138	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
209261012139	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012140	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012141	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012142	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012143	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012144	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012145	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
209261012146	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012147	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012148	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012149	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012150	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
209261012151	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012152	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012153	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012154	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012155	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
209261012156	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
209261012157	Walker A/P-loop; other site
209261012158	ATP binding site [chemical binding]; other site
209261012159	Q-loop/lid; other site
209261012160	ABC transporter signature motif; other site
209261012161	Walker B; other site
209261012162	D-loop; other site
209261012163	H-loop/switch region; other site
209261012164	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
209261012165	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
209261012166	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
209261012167	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
209261012168	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261012169	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
209261012170	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
209261012171	DNA binding residues [nucleotide binding]
209261012172	dimer interface [polypeptide binding]; other site
209261012173	[2Fe-2S] cluster binding site [ion binding]; other site
209261012174	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
209261012175	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
209261012176	putative C-terminal domain interface [polypeptide binding]; other site
209261012177	putative GSH binding site (G-site) [chemical binding]; other site
209261012178	putative dimer interface [polypeptide binding]; other site
209261012179	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
209261012180	putative N-terminal domain interface [polypeptide binding]; other site
209261012181	putative dimer interface [polypeptide binding]; other site
209261012182	putative substrate binding pocket (H-site) [chemical binding]; other site
209261012183	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
209261012184	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
209261012185	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
209261012186	Transcriptional regulator [Transcription]; Region: LysR; COG0583
209261012187	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261012188	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
209261012189	putative dimerization interface [polypeptide binding]; other site
209261012190	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
209261012191	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
209261012192	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
209261012193	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
209261012194	Na binding site [ion binding]; other site
209261012195	Predicted membrane protein [Function unknown]; Region: COG3162
209261012196	acetyl-CoA synthetase; Provisional; Region: PRK00174
209261012197	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
209261012198	active site
209261012199	CoA binding site [chemical binding]; other site
209261012200	acyl-activating enzyme (AAE) consensus motif; other site
209261012201	AMP binding site [chemical binding]; other site
209261012202	acetate binding site [chemical binding]; other site
209261012203	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
209261012204	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
209261012205	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
209261012206	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
209261012207	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
209261012208	heme lyase subunit NrfE; Provisional; Region: PRK10369
209261012209	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
209261012210	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
209261012211	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
209261012212	binding surface
209261012213	TPR motif; other site
209261012214	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
209261012215	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
209261012216	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
209261012217	Sel1-like repeats; Region: SEL1; smart00671
209261012218	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
209261012219	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
209261012220	[4Fe-4S] binding site [ion binding]; other site
209261012221	molybdopterin cofactor binding site; other site
209261012222	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
209261012223	molybdopterin cofactor binding site; other site
209261012224	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
209261012225	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261012226	Coenzyme A binding pocket [chemical binding]; other site
209261012227	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
209261012228	dimer interface [polypeptide binding]; other site
209261012229	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
209261012230	hypothetical protein; Provisional; Region: PRK10220
209261012231	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
209261012232	PhnA protein; Region: PhnA; pfam03831
209261012233	proline/glycine betaine transporter; Provisional; Region: PRK10642
209261012234	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261012235	putative substrate translocation pore; other site
209261012236	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
209261012237	sensor protein BasS/PmrB; Provisional; Region: PRK10755
209261012238	HAMP domain; Region: HAMP; pfam00672
209261012239	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261012240	dimer interface [polypeptide binding]; other site
209261012241	phosphorylation site [posttranslational modification]
209261012242	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261012243	ATP binding site [chemical binding]; other site
209261012244	Mg2+ binding site [ion binding]; other site
209261012245	G-X-G motif; other site
209261012246	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
209261012247	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261012248	active site
209261012249	phosphorylation site [posttranslational modification]
209261012250	intermolecular recognition site; other site
209261012251	dimerization interface [polypeptide binding]; other site
209261012252	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261012253	DNA binding site [nucleotide binding]
209261012254	putative metal dependent hydrolase; Provisional; Region: PRK11598
209261012255	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
209261012256	Sulfatase; Region: Sulfatase; pfam00884
209261012257	arginine:agmatin antiporter; Provisional; Region: PRK10644
209261012258	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
209261012259	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261012260	arginine decarboxylase; Provisional; Region: PRK15029
209261012261	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
209261012262	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
209261012263	homodimer interface [polypeptide binding]; other site
209261012264	pyridoxal 5'-phosphate binding site [chemical binding]; other site
209261012265	catalytic residue [active]
209261012266	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
209261012267	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
209261012268	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261012269	alpha-galactosidase; Provisional; Region: PRK15076
209261012270	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
209261012271	NAD binding site [chemical binding]; other site
209261012272	sugar binding site [chemical binding]; other site
209261012273	divalent metal binding site [ion binding]; other site
209261012274	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
209261012275	dimer interface [polypeptide binding]; other site
209261012276	melibiose:sodium symporter; Provisional; Region: PRK10429
209261012277	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
209261012278	fumarate hydratase; Provisional; Region: PRK15389
209261012279	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
209261012280	Fumarase C-terminus; Region: Fumerase_C; pfam05683
209261012281	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
209261012282	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
209261012283	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
209261012284	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261012285	active site
209261012286	phosphorylation site [posttranslational modification]
209261012287	intermolecular recognition site; other site
209261012288	dimerization interface [polypeptide binding]; other site
209261012289	sensory histidine kinase DcuS; Provisional; Region: PRK11086
209261012290	PAS domain; Region: PAS; smart00091
209261012291	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261012292	ATP binding site [chemical binding]; other site
209261012293	Mg2+ binding site [ion binding]; other site
209261012294	G-X-G motif; other site
209261012295	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
209261012296	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
209261012297	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
209261012298	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
209261012299	SdiA-regulated; Region: SdiA-regulated; cd09971
209261012300	putative active site [active]
209261012301	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
209261012302	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
209261012303	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261012304	DNA binding residues [nucleotide binding]
209261012305	dimerization interface [polypeptide binding]; other site
209261012306	AraC family transcriptional regulator; Provisional; Region: PRK15186
209261012307	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261012308	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
209261012309	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261012310	Coenzyme A binding pocket [chemical binding]; other site
209261012311	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
209261012312	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
209261012313	active site
209261012314	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
209261012315	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
209261012316	P-loop; other site
209261012317	Magnesium ion binding site [ion binding]; other site
209261012318	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
209261012319	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
209261012320	replicative DNA helicase; Region: DnaB; TIGR00665
209261012321	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
209261012322	Walker A motif; other site
209261012323	ATP binding site [chemical binding]; other site
209261012324	Walker B motif; other site
209261012325	DNA binding loops [nucleotide binding]
209261012326	integrating conjugative element, PFGI_1 class, ParB family protein; Region: ICE_PFGI_1_parB; TIGR03764
209261012327	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
209261012328	Helix-turn-helix domain; Region: HTH_36; pfam13730
209261012329	integrating conjugative element protein, PFL_4669 family; Region: ICE_PFL4669; TIGR03761
209261012330	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
209261012331	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
209261012332	active site
209261012333	putative interdomain interaction site [polypeptide binding]; other site
209261012334	putative metal-binding site [ion binding]; other site
209261012335	putative nucleotide binding site [chemical binding]; other site
209261012336	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
209261012337	domain I; other site
209261012338	DNA binding groove [nucleotide binding]
209261012339	phosphate binding site [ion binding]; other site
209261012340	domain II; other site
209261012341	domain III; other site
209261012342	nucleotide binding site [chemical binding]; other site
209261012343	catalytic site [active]
209261012344	domain IV; other site
209261012345	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
209261012346	Protein of unknown function (DUF3577); Region: DUF3577; pfam12101
209261012347	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
209261012348	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
209261012349	dimer interface [polypeptide binding]; other site
209261012350	ssDNA binding site [nucleotide binding]; other site
209261012351	tetramer (dimer of dimers) interface [polypeptide binding]; other site
209261012352	putative single-stranded DNA-binding protein; Region: PHA01740
209261012353	conjugative transfer region protein, TIGR03748 family; Region: conj_PilL
209261012354	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
209261012355	PilM; Region: PilM; pfam07419
209261012356	Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864
209261012357	type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021
209261012358	Type II/IV secretion system protein; Region: T2SE; pfam00437
209261012359	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
209261012360	Walker A motif; other site
209261012361	ATP binding site [chemical binding]; other site
209261012362	Walker B motif; other site
209261012363	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
209261012364	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
209261012365	PilS N terminal; Region: PilS; pfam08805
209261012366	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
209261012367	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
209261012368	N-acetyl-D-glucosamine binding site [chemical binding]; other site
209261012369	catalytic residue [active]
209261012370	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
209261012371	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
209261012372	'prepilin, alternative C-terminal region; corresponds to STY4551 from Accession AL513382: Salmonella typhi CT18'
209261012373	Rci recombinase, C-terminal catalytic domain.  Rci enzymes are found in IncI1 incompatibility group plasmids such as R64.  These recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain...; Region: INT_Rci; cd00796
209261012374	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
209261012375	catalytic residues [active]
209261012376	Int/Topo IB signature motif; other site
209261012377	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
209261012378	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
209261012379	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
209261012380	N-acetyl-D-glucosamine binding site [chemical binding]; other site
209261012381	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
209261012382	Restriction endonuclease; Region: Mrr_cat; pfam04471
209261012383	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
209261012384	conjugative coupling factor TraD, TOL family; Region: conj_TOL_TraD; TIGR03754
209261012385	integrating conjugative element membrane protein, PFL_4697 family; Region: conj_TIGR03747
209261012386	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
209261012387	integrative conjugative element protein, RAQPRD family; Region: ICE_RAQPRD; TIGR01690
209261012388	Protein of unknown function (DUF3262); Region: DUF3262; pfam11660
209261012389	integrating conjugative element membrane protein, PFL_4702 family; Region: conj_TIGR03745
209261012390	integrating conjugative element protein, PFL_4703 family; Region: conj_TIGR03746
209261012391	Protein of unknown function (DUF3438); Region: DUF3438; pfam11920
209261012392	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
209261012393	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
209261012394	integrating conjugative element protein, PFL_4709 family; Region: conj_TIGR03757
209261012395	integrating conjugative element protein, PFL_4710 family; Region: conj_TIGR03756
209261012396	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
209261012397	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
209261012398	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
209261012399	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
209261012400	Active Sites [active]
209261012401	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
209261012402	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
209261012403	ParB-like nuclease domain; Region: ParB; smart00470
209261012404	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
209261012405	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
209261012406	Integrase; Region: Integrase_1; pfam12835
209261012407	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
209261012408	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
209261012409	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
209261012410	Protein of unknown function (DUF3085); Region: DUF3085; pfam11284
209261012411	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
209261012412	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
209261012413	active site
209261012414	DNA binding site [nucleotide binding]
209261012415	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
209261012416	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
209261012417	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
209261012418	tail protein; Provisional; Region: D; PHA02561
209261012419	Phage protein U [General function prediction only]; Region: COG3499
209261012420	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
209261012421	membrane protein P6; Region: PHA01399
209261012422	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
209261012423	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
209261012424	major tail tube protein; Provisional; Region: FII; PHA02600
209261012425	major tail sheath protein; Provisional; Region: FI; PHA02560
209261012426	type III secretion protein SopE; Provisional; Region: PRK15279
209261012427	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
209261012428	SopE GEF domain; Region: SopE_GEF; pfam07487
209261012429	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
209261012430	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
209261012431	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
209261012432	baseplate assembly protein; Provisional; Region: J; PHA02568
209261012433	baseplate wedge subunit; Provisional; Region: W; PHA02516
209261012434	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
209261012435	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
209261012436	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
209261012437	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
209261012438	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
209261012439	catalytic residues [active]
209261012440	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
209261012441	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
209261012442	terminase endonuclease subunit; Provisional; Region: M; PHA02537
209261012443	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
209261012444	capsid protein; Provisional; Region: N; PHA02538
209261012445	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
209261012446	terminase ATPase subunit; Provisional; Region: P; PHA02535
209261012447	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
209261012448	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
209261012449	portal vertex protein; Provisional; Region: Q; PHA02536
209261012450	Phage portal protein; Region: Phage_portal; pfam04860
209261012451	Hydrophobic surface binding protein A; Region: HsbA; pfam12296
209261012452	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
209261012453	DNA adenine methylase (dam); Region: dam; TIGR00571
209261012454	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
209261012455	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
209261012456	active site
209261012457	catalytic site [active]
209261012458	substrate binding site [chemical binding]; other site
209261012459	DksA-like zinc finger domain containing protein; Region: PHA00080
209261012460	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
209261012461	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
209261012462	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
209261012463	Predicted transcriptional regulator [Transcription]; Region: COG2932
209261012464	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
209261012465	integrase; Provisional; Region: int; PHA02601
209261012466	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
209261012467	dimer interface [polypeptide binding]; other site
209261012468	active site
209261012469	catalytic residues [active]
209261012470	Int/Topo IB signature motif; other site
209261012471	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
209261012472	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
209261012473	Catalytic site [active]
209261012474	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
209261012475	hypothetical protein; Provisional; Region: PRK13687
209261012476	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261012477	S-adenosylmethionine binding site [chemical binding]; other site
209261012478	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
209261012479	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261012480	S-adenosylmethionine binding site [chemical binding]; other site
209261012481	Vi polysaccharide export protein VexE; Provisional; Region: PRK15174
209261012482	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
209261012483	TPR motif; other site
209261012484	binding surface
209261012485	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
209261012486	putative acyl-acceptor binding pocket; other site
209261012487	Vi polysaccharide export inner membrane protein VexD; Provisional; Region: PRK15178
209261012488	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
209261012489	Vi polysaccharide export ATP-binding protein VexC; Provisional; Region: PRK15177
209261012490	Walker A/P-loop; other site
209261012491	ATP binding site [chemical binding]; other site
209261012492	Q-loop/lid; other site
209261012493	ABC transporter signature motif; other site
209261012494	Walker B; other site
209261012495	D-loop; other site
209261012496	H-loop/switch region; other site
209261012497	Vi polysaccharide export inner membrane protein VexB; Provisional; Region: PRK15176
209261012498	Vi polysaccharide export protein VexA; Provisional; Region: PRK15175
209261012499	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
209261012500	Vi polysaccharide biosynthesis protein TviE; Provisional; Region: PRK15490
209261012501	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
209261012502	Vi polysaccharide biosynthesis protein TviD; Provisional; Region: PRK15180
209261012503	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
209261012504	UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256
209261012505	NAD binding site [chemical binding]; other site
209261012506	substrate binding site [chemical binding]; other site
209261012507	homodimer interface [polypeptide binding]; other site
209261012508	active site
209261012509	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
209261012510	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
209261012511	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
209261012512	Vi polysaccharide biosynthesis protein TviA; Provisional; Region: PRK15183
209261012513	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
209261012514	Family description; Region: UvrD_C_2; pfam13538
209261012515	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
209261012516	Putative helicase; Region: TraI_2; pfam07514
209261012517	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
209261012518	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
209261012519	active site
209261012520	catalytic residues [active]
209261012521	DNA binding site [nucleotide binding]
209261012522	Int/Topo IB signature motif; other site
209261012523	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
209261012524	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261012525	Coenzyme A binding pocket [chemical binding]; other site
209261012526	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
209261012527	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
209261012528	Integrase; Region: Integrase_1; pfam12835
209261012529	Bacterial SH3 domain homologues; Region: SH3b; smart00287
209261012530	integrase; Provisional; Region: PRK09692
209261012531	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
209261012532	active site
209261012533	Int/Topo IB signature motif; other site
209261012534	putative transcriptional regulator; Provisional; Region: PRK11640
209261012535	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
209261012536	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
209261012537	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
209261012538	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
209261012539	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
209261012540	DsbD alpha interface [polypeptide binding]; other site
209261012541	catalytic residues [active]
209261012542	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
209261012543	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
209261012544	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
209261012545	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
209261012546	Aspartase; Region: Aspartase; cd01357
209261012547	active sites [active]
209261012548	tetramer interface [polypeptide binding]; other site
209261012549	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
209261012550	putative transporter; Provisional; Region: PRK11021
209261012551	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
209261012552	oligomerisation interface [polypeptide binding]; other site
209261012553	mobile loop; other site
209261012554	roof hairpin; other site
209261012555	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
209261012556	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
209261012557	ring oligomerisation interface [polypeptide binding]; other site
209261012558	ATP/Mg binding site [chemical binding]; other site
209261012559	stacking interactions; other site
209261012560	hinge regions; other site
209261012561	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
209261012562	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
209261012563	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261012564	FeS/SAM binding site; other site
209261012565	elongation factor P; Validated; Region: PRK00529
209261012566	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
209261012567	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
209261012568	RNA binding site [nucleotide binding]; other site
209261012569	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
209261012570	RNA binding site [nucleotide binding]; other site
209261012571	Predicted small secreted protein [Function unknown]; Region: COG5510
209261012572	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
209261012573	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
209261012574	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261012575	DNA binding residues [nucleotide binding]
209261012576	dimerization interface [polypeptide binding]; other site
209261012577	multidrug efflux system protein; Provisional; Region: PRK11431
209261012578	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
209261012579	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
209261012580	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
209261012581	Iron-sulfur protein interface; other site
209261012582	proximal quinone binding site [chemical binding]; other site
209261012583	C-subunit interface; other site
209261012584	distal quinone binding site; other site
209261012585	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
209261012586	D-subunit interface [polypeptide binding]; other site
209261012587	Iron-sulfur protein interface; other site
209261012588	proximal quinone binding site [chemical binding]; other site
209261012589	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
209261012590	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
209261012591	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
209261012592	L-aspartate oxidase; Provisional; Region: PRK06175
209261012593	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
209261012594	poxB regulator PoxA; Provisional; Region: PRK09350
209261012595	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
209261012596	motif 1; other site
209261012597	dimer interface [polypeptide binding]; other site
209261012598	active site
209261012599	motif 2; other site
209261012600	motif 3; other site
209261012601	inner membrane transporter YjeM; Provisional; Region: PRK15238
209261012602	putative mechanosensitive channel protein; Provisional; Region: PRK10929
209261012603	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
209261012604	Mechanosensitive ion channel; Region: MS_channel; pfam00924
209261012605	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
209261012606	GTPase RsgA; Reviewed; Region: PRK12288
209261012607	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
209261012608	RNA binding site [nucleotide binding]; other site
209261012609	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
209261012610	GTPase/Zn-binding domain interface [polypeptide binding]; other site
209261012611	GTP/Mg2+ binding site [chemical binding]; other site
209261012612	G4 box; other site
209261012613	G5 box; other site
209261012614	G1 box; other site
209261012615	Switch I region; other site
209261012616	G2 box; other site
209261012617	G3 box; other site
209261012618	Switch II region; other site
209261012619	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
209261012620	catalytic site [active]
209261012621	putative active site [active]
209261012622	putative substrate binding site [chemical binding]; other site
209261012623	dimer interface [polypeptide binding]; other site
209261012624	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
209261012625	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
209261012626	substrate binding pocket [chemical binding]; other site
209261012627	membrane-bound complex binding site; other site
209261012628	hinge residues; other site
209261012629	epoxyqueuosine reductase; Region: TIGR00276
209261012630	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
209261012631	putative carbohydrate kinase; Provisional; Region: PRK10565
209261012632	Uncharacterized conserved protein [Function unknown]; Region: COG0062
209261012633	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
209261012634	putative substrate binding site [chemical binding]; other site
209261012635	putative ATP binding site [chemical binding]; other site
209261012636	ADP-binding protein; Provisional; Region: PRK10646
209261012637	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
209261012638	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
209261012639	active site
209261012640	metal binding site [ion binding]; metal-binding site
209261012641	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
209261012642	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261012643	ATP binding site [chemical binding]; other site
209261012644	Mg2+ binding site [ion binding]; other site
209261012645	G-X-G motif; other site
209261012646	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
209261012647	ATP binding site [chemical binding]; other site
209261012648	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
209261012649	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
209261012650	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
209261012651	bacterial Hfq-like; Region: Hfq; cd01716
209261012652	hexamer interface [polypeptide binding]; other site
209261012653	Sm1 motif; other site
209261012654	RNA binding site [nucleotide binding]; other site
209261012655	Sm2 motif; other site
209261012656	GTPase HflX; Provisional; Region: PRK11058
209261012657	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
209261012658	HflX GTPase family; Region: HflX; cd01878
209261012659	G1 box; other site
209261012660	GTP/Mg2+ binding site [chemical binding]; other site
209261012661	Switch I region; other site
209261012662	G2 box; other site
209261012663	G3 box; other site
209261012664	Switch II region; other site
209261012665	G4 box; other site
209261012666	G5 box; other site
209261012667	FtsH protease regulator HflK; Provisional; Region: PRK10930
209261012668	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
209261012669	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
209261012670	FtsH protease regulator HflC; Provisional; Region: PRK11029
209261012671	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
209261012672	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
209261012673	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
209261012674	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
209261012675	GDP-binding site [chemical binding]; other site
209261012676	ACT binding site; other site
209261012677	IMP binding site; other site
209261012678	Predicted transcriptional regulator [Transcription]; Region: COG1959
209261012679	transcriptional repressor NsrR; Provisional; Region: PRK11014
209261012680	exoribonuclease R; Provisional; Region: PRK11642
209261012681	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
209261012682	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
209261012683	RNB domain; Region: RNB; pfam00773
209261012684	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
209261012685	RNA binding site [nucleotide binding]; other site
209261012686	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
209261012687	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
209261012688	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
209261012689	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
209261012690	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
209261012691	Predicted membrane protein [Function unknown]; Region: COG3766
209261012692	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
209261012693	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
209261012694	Predicted integral membrane protein [Function unknown]; Region: COG5463
209261012695	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
209261012696	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
209261012697	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
209261012698	FAD binding site [chemical binding]; other site
209261012699	substrate binding site [chemical binding]; other site
209261012700	catalytic residues [active]
209261012701	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
209261012702	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
209261012703	esterase; Provisional; Region: PRK10566
209261012704	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
209261012705	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
209261012706	transcriptional repressor UlaR; Provisional; Region: PRK13509
209261012707	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
209261012708	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
209261012709	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
209261012710	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
209261012711	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
209261012712	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
209261012713	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
209261012714	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
209261012715	active site
209261012716	phosphorylation site [posttranslational modification]
209261012717	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
209261012718	active site
209261012719	dimer interface [polypeptide binding]; other site
209261012720	magnesium binding site [ion binding]; other site
209261012721	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
209261012722	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
209261012723	AP (apurinic/apyrimidinic) site pocket; other site
209261012724	DNA interaction; other site
209261012725	Metal-binding active site; metal-binding site
209261012726	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
209261012727	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
209261012728	intersubunit interface [polypeptide binding]; other site
209261012729	active site
209261012730	Zn2+ binding site [ion binding]; other site
209261012731	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
209261012732	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
209261012733	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
209261012734	dimer interface [polypeptide binding]; other site
209261012735	ssDNA binding site [nucleotide binding]; other site
209261012736	tetramer (dimer of dimers) interface [polypeptide binding]; other site
209261012737	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
209261012738	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
209261012739	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
209261012740	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
209261012741	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
209261012742	EamA-like transporter family; Region: EamA; pfam00892
209261012743	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
209261012744	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
209261012745	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
209261012746	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
209261012747	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
209261012748	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
209261012749	DKNYY family; Region: DKNYY; pfam13644
209261012750	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
209261012751	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
209261012752	Hemerythrin-like domain; Region: Hr-like; cd12108
209261012753	Fe binding site [ion binding]; other site
209261012754	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
209261012755	EamA-like transporter family; Region: EamA; pfam00892
209261012756	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
209261012757	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
209261012758	NADP binding site [chemical binding]; other site
209261012759	Predicted transcriptional regulators [Transcription]; Region: COG1733
209261012760	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
209261012761	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
209261012762	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
209261012763	active site
209261012764	metal binding site [ion binding]; metal-binding site
209261012765	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
209261012766	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
209261012767	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
209261012768	active site
209261012769	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
209261012770	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
209261012771	Transposase IS200 like; Region: Y1_Tnp; pfam01797
209261012772	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
209261012773	Domain of unknown function DUF21; Region: DUF21; pfam01595
209261012774	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
209261012775	Transporter associated domain; Region: CorC_HlyC; smart01091
209261012776	methionine sulfoxide reductase A; Provisional; Region: PRK00058
209261012777	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
209261012778	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
209261012779	Surface antigen; Region: Bac_surface_Ag; pfam01103
209261012780	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
209261012781	Family of unknown function (DUF490); Region: DUF490; pfam04357
209261012782	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
209261012783	putative active site pocket [active]
209261012784	dimerization interface [polypeptide binding]; other site
209261012785	putative catalytic residue [active]
209261012786	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261012787	D-galactonate transporter; Region: 2A0114; TIGR00893
209261012788	putative substrate translocation pore; other site
209261012789	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
209261012790	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
209261012791	active site
209261012792	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
209261012793	dimer interface [polypeptide binding]; other site
209261012794	substrate binding site [chemical binding]; other site
209261012795	metal binding sites [ion binding]; metal-binding site
209261012796	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
209261012797	AMP binding site [chemical binding]; other site
209261012798	metal binding site [ion binding]; metal-binding site
209261012799	active site
209261012800	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
209261012801	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
209261012802	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
209261012803	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
209261012804	hypothetical protein; Provisional; Region: PRK05255
209261012805	peptidase PmbA; Provisional; Region: PRK11040
209261012806	cytochrome b562; Provisional; Region: PRK15058
209261012807	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
209261012808	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
209261012809	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
209261012810	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
209261012811	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
209261012812	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
209261012813	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
209261012814	active site
209261012815	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
209261012816	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
209261012817	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
209261012818	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
209261012819	HTH domain; Region: HTH_11; pfam08279
209261012820	Mga helix-turn-helix domain; Region: Mga; pfam05043
209261012821	PRD domain; Region: PRD; pfam00874
209261012822	PRD domain; Region: PRD; pfam00874
209261012823	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
209261012824	active site
209261012825	P-loop; other site
209261012826	phosphorylation site [posttranslational modification]
209261012827	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
209261012828	active site
209261012829	phosphorylation site [posttranslational modification]
209261012830	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
209261012831	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
209261012832	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
209261012833	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261012834	FeS/SAM binding site; other site
209261012835	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
209261012836	ATP cone domain; Region: ATP-cone; pfam03477
209261012837	Class III ribonucleotide reductase; Region: RNR_III; cd01675
209261012838	effector binding site; other site
209261012839	active site
209261012840	Zn binding site [ion binding]; other site
209261012841	glycine loop; other site
209261012842	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
209261012843	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
209261012844	Ca binding site [ion binding]; other site
209261012845	active site
209261012846	catalytic site [active]
209261012847	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
209261012848	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
209261012849	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
209261012850	active site turn [active]
209261012851	phosphorylation site [posttranslational modification]
209261012852	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
209261012853	trehalose repressor; Provisional; Region: treR; PRK09492
209261012854	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261012855	DNA binding site [nucleotide binding]
209261012856	domain linker motif; other site
209261012857	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
209261012858	dimerization interface [polypeptide binding]; other site
209261012859	ligand binding site [chemical binding]; other site
209261012860	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
209261012861	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
209261012862	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
209261012863	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
209261012864	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
209261012865	Soluble P-type ATPase [General function prediction only]; Region: COG4087
209261012866	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
209261012867	Transposase; Region: HTH_Tnp_1; cl17663
209261012868	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
209261012869	homotrimer interaction site [polypeptide binding]; other site
209261012870	putative active site [active]
209261012871	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
209261012872	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
209261012873	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
209261012874	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
209261012875	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
209261012876	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
209261012877	pyrBI operon leader peptide; Provisional; Region: PRK10224
209261012878	Arginine repressor [Transcription]; Region: ArgR; COG1438
209261012879	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
209261012880	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
209261012881	Predicted membrane protein [Function unknown]; Region: COG1288
209261012882	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
209261012883	ornithine carbamoyltransferase; Validated; Region: PRK02102
209261012884	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
209261012885	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
209261012886	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
209261012887	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
209261012888	putative substrate binding site [chemical binding]; other site
209261012889	nucleotide binding site [chemical binding]; other site
209261012890	nucleotide binding site [chemical binding]; other site
209261012891	homodimer interface [polypeptide binding]; other site
209261012892	arginine deiminase; Provisional; Region: PRK01388
209261012893	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
209261012894	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
209261012895	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
209261012896	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
209261012897	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
209261012898	RNase E inhibitor protein; Provisional; Region: PRK11191
209261012899	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
209261012900	active site
209261012901	dinuclear metal binding site [ion binding]; other site
209261012902	dimerization interface [polypeptide binding]; other site
209261012903	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
209261012904	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
209261012905	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261012906	Coenzyme A binding pocket [chemical binding]; other site
209261012907	Predicted membrane protein [Function unknown]; Region: COG4269
209261012908	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
209261012909	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
209261012910	HIGH motif; other site
209261012911	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
209261012912	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
209261012913	active site
209261012914	KMSKS motif; other site
209261012915	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
209261012916	tRNA binding surface [nucleotide binding]; other site
209261012917	anticodon binding site; other site
209261012918	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
209261012919	DNA polymerase III subunit chi; Validated; Region: PRK05728
209261012920	multifunctional aminopeptidase A; Provisional; Region: PRK00913
209261012921	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
209261012922	interface (dimer of trimers) [polypeptide binding]; other site
209261012923	Substrate-binding/catalytic site; other site
209261012924	Zn-binding sites [ion binding]; other site
209261012925	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
209261012926	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
209261012927	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
209261012928	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
209261012929	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
209261012930	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
209261012931	DNA binding site [nucleotide binding]
209261012932	domain linker motif; other site
209261012933	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
209261012934	putative dimerization interface [polypeptide binding]; other site
209261012935	putative ligand binding site [chemical binding]; other site
209261012936	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
209261012937	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
209261012938	gluconate transporter; Region: gntP; TIGR00791
209261012939	fructuronate transporter; Provisional; Region: PRK10034; cl15264
209261012940	integrase; Provisional; Region: PRK09692
209261012941	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
209261012942	active site
209261012943	Int/Topo IB signature motif; other site
209261012944	Catalytic domain of Protein Kinases; Region: PKc; cd00180
209261012945	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
209261012946	active site
209261012947	ATP binding site [chemical binding]; other site
209261012948	substrate binding site [chemical binding]; other site
209261012949	activation loop (A-loop); other site
209261012950	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
209261012951	Catalytic domain of Protein Kinases; Region: PKc; cd00180
209261012952	active site
209261012953	ATP binding site [chemical binding]; other site
209261012954	substrate binding site [chemical binding]; other site
209261012955	activation loop (A-loop); other site
209261012956	Serine/threonine protein phosphatase [Signal transduction mechanisms]; Region: PTC1; COG0631
209261012957	active site
209261012958	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
209261012959	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
209261012960	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
209261012961	Ash protein family; Region: Phage_ASH; pfam10554
209261012962	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
209261012963	putative fimbrial chaperone protein SefB; Provisional; Region: PRK15233
209261012964	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261012965	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261012966	outer membrane fimbrial usher protein SefC; Provisional; Region: PRK15235
209261012967	PapC N-terminal domain; Region: PapC_N; pfam13954
209261012968	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
209261012969	PapC C-terminal domain; Region: PapC_C; pfam13953
209261012970	FaeA-like protein; Region: FaeA; pfam04703
209261012971	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261012972	DNA binding residues [nucleotide binding]
209261012973	dimerization interface [polypeptide binding]; other site
209261012974	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
209261012975	SdiA-regulated; Region: SdiA-regulated; cd09971
209261012976	putative active site [active]
209261012977	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
209261012978	nucleotide binding region [chemical binding]; other site
209261012979	ATP-binding site [chemical binding]; other site
209261012980	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
209261012981	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only]; Region: COG1205
209261012982	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261012983	ATP binding site [chemical binding]; other site
209261012984	putative Mg++ binding site [ion binding]; other site
209261012985	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
209261012986	HNH endonuclease; Region: HNH_2; pfam13391
209261012987	hypothetical protein; Provisional; Region: PRK12378
209261012988	Methyltransferase domain; Region: Methyltransf_23; pfam13489
209261012989	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261012990	S-adenosylmethionine binding site [chemical binding]; other site
209261012991	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261012992	S-adenosylmethionine binding site [chemical binding]; other site
209261012993	hypothetical protein; Provisional; Region: PRK13687
209261012994	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
209261012995	Uncharacterized conserved protein [Function unknown]; Region: COG3439
209261012996	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
209261012997	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
209261012998	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
209261012999	DNA-binding site [nucleotide binding]; DNA binding site
209261013000	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
209261013001	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
209261013002	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
209261013003	active site
209261013004	HIGH motif; other site
209261013005	dimer interface [polypeptide binding]; other site
209261013006	KMSKS motif; other site
209261013007	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
209261013008	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
209261013009	aspartate racemase; Region: asp_race; TIGR00035
209261013010	cell density-dependent motility repressor; Provisional; Region: PRK10082
209261013011	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
209261013012	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
209261013013	dimerization interface [polypeptide binding]; other site
209261013014	isoaspartyl dipeptidase; Provisional; Region: PRK10657
209261013015	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
209261013016	active site
209261013017	hypothetical protein; Provisional; Region: PRK10519
209261013018	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
209261013019	Nucleoside recognition; Region: Gate; pfam07670
209261013020	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
209261013021	Predicted membrane protein [Function unknown]; Region: COG2733
209261013022	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
209261013023	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
209261013024	putative substrate translocation pore; other site
209261013025	putative transposase; Provisional; Region: PRK09857
209261013026	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
209261013027	endoribonuclease SymE; Provisional; Region: PRK13605
209261013028	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
209261013029	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
209261013030	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
209261013031	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
209261013032	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
209261013033	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
209261013034	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
209261013035	ATP binding site [chemical binding]; other site
209261013036	putative Mg++ binding site [ion binding]; other site
209261013037	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
209261013038	Mrr N-terminal domain; Region: Mrr_N; pfam14338
209261013039	Restriction endonuclease; Region: Mrr_cat; pfam04471
209261013040	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
209261013041	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
209261013042	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
209261013043	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
209261013044	P-loop, Walker A motif; other site
209261013045	Base recognition motif; other site
209261013046	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
209261013047	Uncharacterized small protein [Function unknown]; Region: COG2879
209261013048	carbon starvation protein A; Provisional; Region: PRK15015
209261013049	Carbon starvation protein CstA; Region: CstA; pfam02554
209261013050	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
209261013051	phosphoglycerol transferase I; Provisional; Region: PRK03776
209261013052	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
209261013053	hypothetical protein; Provisional; Region: PRK11667
209261013054	DNA replication protein DnaC; Validated; Region: PRK07952
209261013055	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
209261013056	Walker A motif; other site
209261013057	ATP binding site [chemical binding]; other site
209261013058	Walker B motif; other site
209261013059	primosomal protein DnaI; Provisional; Region: PRK02854
209261013060	hypothetical protein; Provisional; Region: PRK09917
209261013061	Uncharacterized conserved protein [Function unknown]; Region: COG2966
209261013062	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
209261013063	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
209261013064	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261013065	DNA binding residues [nucleotide binding]
209261013066	dimerization interface [polypeptide binding]; other site
209261013067	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
209261013068	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
209261013069	DNA binding residues [nucleotide binding]
209261013070	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
209261013071	putative deacylase active site [active]
209261013072	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
209261013073	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
209261013074	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
209261013075	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
209261013076	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
209261013077	metal binding site [ion binding]; metal-binding site
209261013078	active site
209261013079	I-site; other site
209261013080	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
209261013081	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
209261013082	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
209261013083	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
209261013084	S-adenosylmethionine binding site [chemical binding]; other site
209261013085	DNA polymerase III subunit psi; Validated; Region: PRK06856
209261013086	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
209261013087	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
209261013088	Coenzyme A binding pocket [chemical binding]; other site
209261013089	dUMP phosphatase; Provisional; Region: PRK09449
209261013090	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261013091	motif II; other site
209261013092	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
209261013093	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
209261013094	G1 box; other site
209261013095	putative GEF interaction site [polypeptide binding]; other site
209261013096	GTP/Mg2+ binding site [chemical binding]; other site
209261013097	Switch I region; other site
209261013098	G2 box; other site
209261013099	G3 box; other site
209261013100	Switch II region; other site
209261013101	G4 box; other site
209261013102	G5 box; other site
209261013103	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
209261013104	periplasmic protein; Provisional; Region: PRK10568
209261013105	BON domain; Region: BON; pfam04972
209261013106	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
209261013107	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
209261013108	active site
209261013109	nucleophile elbow; other site
209261013110	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
209261013111	active site
209261013112	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
209261013113	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
209261013114	FeS/SAM binding site; other site
209261013115	hypothetical protein; Provisional; Region: PRK10977
209261013116	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
209261013117	intersubunit interface [polypeptide binding]; other site
209261013118	active site
209261013119	catalytic residue [active]
209261013120	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
209261013121	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
209261013122	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
209261013123	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
209261013124	phosphopentomutase; Provisional; Region: PRK05362
209261013125	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
209261013126	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
209261013127	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
209261013128	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
209261013129	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
209261013130	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
209261013131	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
209261013132	hypothetical protein; Provisional; Region: PRK11246
209261013133	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
209261013134	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
209261013135	motif II; other site
209261013136	DNA repair protein RadA; Region: sms; TIGR00416
209261013137	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
209261013138	Walker A motif/ATP binding site; other site
209261013139	ATP binding site [chemical binding]; other site
209261013140	Walker B motif; other site
209261013141	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
209261013142	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
209261013143	non-specific DNA binding site [nucleotide binding]; other site
209261013144	salt bridge; other site
209261013145	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
209261013146	sequence-specific DNA binding site [nucleotide binding]; other site
209261013147	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
209261013148	active site
209261013149	(T/H)XGH motif; other site
209261013150	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
209261013151	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
209261013152	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
209261013153	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
209261013154	ABC transporter; Region: ABC_tran_2; pfam12848
209261013155	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
209261013156	lytic murein transglycosylase; Provisional; Region: PRK11619
209261013157	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
209261013158	N-acetyl-D-glucosamine binding site [chemical binding]; other site
209261013159	catalytic residue [active]
209261013160	Trp operon repressor; Provisional; Region: PRK01381
209261013161	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
209261013162	catalytic core [active]
209261013163	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
209261013164	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
209261013165	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
209261013166	hypothetical protein; Provisional; Region: PRK10756
209261013167	CreA protein; Region: CreA; pfam05981
209261013168	DNA-binding response regulator CreB; Provisional; Region: PRK11083
209261013169	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261013170	active site
209261013171	phosphorylation site [posttranslational modification]
209261013172	intermolecular recognition site; other site
209261013173	dimerization interface [polypeptide binding]; other site
209261013174	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261013175	DNA binding site [nucleotide binding]
209261013176	sensory histidine kinase CreC; Provisional; Region: PRK11100
209261013177	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
209261013178	dimerization interface [polypeptide binding]; other site
209261013179	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
209261013180	dimer interface [polypeptide binding]; other site
209261013181	phosphorylation site [posttranslational modification]
209261013182	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
209261013183	ATP binding site [chemical binding]; other site
209261013184	Mg2+ binding site [ion binding]; other site
209261013185	G-X-G motif; other site
209261013186	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
209261013187	putative fimbrial protein SthD; Provisional; Region: PRK15293
209261013188	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
209261013189	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
209261013190	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
209261013191	putative fimbrial protein SthA; Provisional; Region: PRK15296
209261013192	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
209261013193	Helix-turn-helix domain; Region: HTH_36; pfam13730
209261013194	two-component response regulator; Provisional; Region: PRK11173
209261013195	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
209261013196	active site
209261013197	phosphorylation site [posttranslational modification]
209261013198	intermolecular recognition site; other site
209261013199	dimerization interface [polypeptide binding]; other site
209261013200	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
209261013201	DNA binding site [nucleotide binding]
209261013202	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
209261013203	putative RNA methyltransferase; Provisional; Region: PRK10433