-- dump date   	20140620_055031
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1008297000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1008297000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1008297000003	putative catalytic residues [active]
1008297000004	putative nucleotide binding site [chemical binding]; other site
1008297000005	putative aspartate binding site [chemical binding]; other site
1008297000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1008297000007	dimer interface [polypeptide binding]; other site
1008297000008	putative threonine allosteric regulatory site; other site
1008297000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1008297000010	putative threonine allosteric regulatory site; other site
1008297000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1008297000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1008297000013	homoserine kinase; Provisional; Region: PRK01212
1008297000014	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1008297000015	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1008297000016	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1008297000017	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297000018	catalytic residue [active]
1008297000019	hypothetical protein; Validated; Region: PRK02101
1008297000020	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1008297000021	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1008297000022	transaldolase-like protein; Provisional; Region: PTZ00411
1008297000023	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1008297000024	active site
1008297000025	dimer interface [polypeptide binding]; other site
1008297000026	catalytic residue [active]
1008297000027	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1008297000028	MPT binding site; other site
1008297000029	trimer interface [polypeptide binding]; other site
1008297000030	hypothetical protein; Provisional; Region: PRK10659
1008297000031	hypothetical protein; Provisional; Region: PRK10236
1008297000032	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1008297000033	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1008297000034	Protein of unknown function (DUF2541); Region: DUF2541; cl08090
1008297000035	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1008297000036	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1008297000037	nucleotide binding site [chemical binding]; other site
1008297000038	chaperone protein DnaJ; Provisional; Region: PRK10767
1008297000039	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1008297000040	HSP70 interaction site [polypeptide binding]; other site
1008297000041	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1008297000042	substrate binding site [polypeptide binding]; other site
1008297000043	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1008297000044	Zn binding sites [ion binding]; other site
1008297000045	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1008297000046	dimer interface [polypeptide binding]; other site
1008297000047	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297000048	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297000049	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1008297000050	substrate binding pocket [chemical binding]; other site
1008297000051	dimerization interface [polypeptide binding]; other site
1008297000052	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1008297000053	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1008297000054	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1008297000055	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1008297000056	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
1008297000057	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1008297000058	active site
1008297000059	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1008297000060	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1008297000061	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1008297000062	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1008297000063	Helix-turn-helix domain; Region: HTH_36; pfam13730
1008297000064	fimbrial protein BcfA; Provisional; Region: PRK15187
1008297000065	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
1008297000066	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297000067	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297000068	outer membrane usher protein; Provisional; Region: PRK15193
1008297000069	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297000070	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297000071	PapC C-terminal domain; Region: PapC_C; pfam13953
1008297000072	fimbrial protein BcfD; Provisional; Region: PRK15189
1008297000073	fimbrial protein BcfE; Provisional; Region: PRK15190
1008297000074	fimbrial protein BcfF; Provisional; Region: PRK15191
1008297000075	fimbrial chaperone BcfG; Provisional; Region: PRK15192
1008297000076	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297000077	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297000078	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1008297000079	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1008297000080	catalytic residues [active]
1008297000081	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1008297000082	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297000083	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297000084	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297000085	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1008297000086	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1008297000087	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1008297000088	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1008297000089	active site
1008297000090	metal binding site [ion binding]; metal-binding site
1008297000091	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1008297000092	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
1008297000093	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1008297000094	Sulfatase; Region: Sulfatase; pfam00884
1008297000095	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1008297000096	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297000097	FeS/SAM binding site; other site
1008297000098	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1008297000099	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1008297000100	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1008297000101	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1008297000102	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1008297000103	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297000104	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1008297000105	putative dimerization interface [polypeptide binding]; other site
1008297000106	putative alpha-glucosidase; Provisional; Region: PRK10658
1008297000107	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1008297000108	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
1008297000109	putative active site [active]
1008297000110	putative catalytic site [active]
1008297000111	potential frameshift: common BLAST hit: gi|379699261|ref|YP_005240989.1| putative sodium galactoside symporter
1008297000112	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1008297000113	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1008297000114	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1008297000115	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1008297000116	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
1008297000117	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1008297000118	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1008297000119	active site
1008297000120	Riboflavin kinase; Region: Flavokinase; smart00904
1008297000121	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1008297000122	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1008297000123	active site
1008297000124	HIGH motif; other site
1008297000125	nucleotide binding site [chemical binding]; other site
1008297000126	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1008297000127	active site
1008297000128	KMSKS motif; other site
1008297000129	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1008297000130	tRNA binding surface [nucleotide binding]; other site
1008297000131	anticodon binding site; other site
1008297000132	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1008297000133	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1008297000134	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1008297000135	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1008297000136	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1008297000137	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1008297000138	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1008297000139	active site
1008297000140	tetramer interface [polypeptide binding]; other site
1008297000141	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1008297000142	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297000143	active site
1008297000144	phosphorylation site [posttranslational modification]
1008297000145	intermolecular recognition site; other site
1008297000146	dimerization interface [polypeptide binding]; other site
1008297000147	Transcriptional regulator; Region: CitT; pfam12431
1008297000148	two-component sensor kinase
1008297000149	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
1008297000150	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
1008297000151	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1008297000152	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1008297000153	active site
1008297000154	catalytic residues [active]
1008297000155	metal binding site [ion binding]; metal-binding site
1008297000156	homodimer binding site [polypeptide binding]; other site
1008297000157	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1008297000158	carboxyltransferase (CT) interaction site; other site
1008297000159	biotinylation site [posttranslational modification]; other site
1008297000160	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1008297000161	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1008297000162	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1008297000163	putative active site [active]
1008297000164	(T/H)XGH motif; other site
1008297000165	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1008297000166	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1008297000167	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1008297000168	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1008297000169	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1008297000170	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
1008297000171	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1008297000172	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1008297000173	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1008297000174	Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarA; COG0505
1008297000175	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1008297000176	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1008297000177	catalytic site [active]
1008297000178	subunit interface [polypeptide binding]; other site
1008297000179	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1008297000180	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1008297000181	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1008297000182	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1008297000183	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1008297000184	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1008297000185	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1008297000186	IMP binding site; other site
1008297000187	dimer interface [polypeptide binding]; other site
1008297000188	interdomain contacts; other site
1008297000189	partial ornithine binding site; other site
1008297000190	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
1008297000191	carnitine operon protein CaiE; Provisional; Region: PRK13627
1008297000192	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1008297000193	putative trimer interface [polypeptide binding]; other site
1008297000194	putative metal binding site [ion binding]; other site
1008297000195	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
1008297000196	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1008297000197	substrate binding site [chemical binding]; other site
1008297000198	oxyanion hole (OAH) forming residues; other site
1008297000199	trimer interface [polypeptide binding]; other site
1008297000200	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
1008297000201	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
1008297000202	acyl-activating enzyme (AAE) consensus motif; other site
1008297000203	putative AMP binding site [chemical binding]; other site
1008297000204	putative active site [active]
1008297000205	putative CoA binding site [chemical binding]; other site
1008297000206	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
1008297000207	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1008297000208	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
1008297000209	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1008297000210	active site
1008297000211	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
1008297000212	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1008297000213	Ligand binding site [chemical binding]; other site
1008297000214	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1008297000215	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
1008297000216	Electron transfer flavoprotein domain; Region: ETF; smart00893
1008297000217	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1008297000218	putative oxidoreductase FixC; Provisional; Region: PRK10157
1008297000219	ferredoxin-like protein FixX; Provisional; Region: PRK15449
1008297000220	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297000221	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1008297000222	putative substrate translocation pore; other site
1008297000223	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1008297000224	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1008297000225	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1008297000226	Sulfatase; Region: Sulfatase; cl17466
1008297000227	Sulfatase; Region: Sulfatase; cl17466
1008297000228	Sulfatase; Region: Sulfatase; cl17466
1008297000229	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1008297000230	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1008297000231	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1008297000232	TrkA-N domain; Region: TrkA_N; pfam02254
1008297000233	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1008297000234	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1008297000235	folate binding site [chemical binding]; other site
1008297000236	NADP+ binding site [chemical binding]; other site
1008297000237	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1008297000238	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1008297000239	active site
1008297000240	metal binding site [ion binding]; metal-binding site
1008297000241	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1008297000242	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1008297000243	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1008297000244	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1008297000245	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1008297000246	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1008297000247	SurA N-terminal domain; Region: SurA_N; pfam09312
1008297000248	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1008297000249	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1008297000250	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1008297000251	OstA-like protein; Region: OstA; pfam03968
1008297000252	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1008297000253	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1008297000254	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1008297000255	putative metal binding site [ion binding]; other site
1008297000256	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1008297000257	HSP70 interaction site [polypeptide binding]; other site
1008297000258	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1008297000259	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1008297000260	active site
1008297000261	ATP-dependent helicase HepA; Validated; Region: PRK04914
1008297000262	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1008297000263	ATP binding site [chemical binding]; other site
1008297000264	putative Mg++ binding site [ion binding]; other site
1008297000265	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297000266	nucleotide binding region [chemical binding]; other site
1008297000267	ATP-binding site [chemical binding]; other site
1008297000268	DNA polymerase II; Reviewed; Region: PRK05762
1008297000269	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1008297000270	active site
1008297000271	catalytic site [active]
1008297000272	substrate binding site [chemical binding]; other site
1008297000273	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1008297000274	active site
1008297000275	metal-binding site
1008297000276	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1008297000277	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1008297000278	putative active site [active]
1008297000279	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1008297000280	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1008297000281	intersubunit interface [polypeptide binding]; other site
1008297000282	active site
1008297000283	Zn2+ binding site [ion binding]; other site
1008297000284	L-arabinose isomerase; Provisional; Region: PRK02929
1008297000285	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1008297000286	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1008297000287	trimer interface [polypeptide binding]; other site
1008297000288	putative substrate binding site [chemical binding]; other site
1008297000289	putative metal binding site [ion binding]; other site
1008297000290	ribulokinase; Provisional; Region: PRK04123
1008297000291	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1008297000292	active site
1008297000293	N- and C-terminal domain interface [polypeptide binding]; other site
1008297000294	MgATP binding site [chemical binding]; other site
1008297000295	carbohydrate binding site [chemical binding]; other site
1008297000296	homodimer interface [polypeptide binding]; other site
1008297000297	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1008297000298	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1008297000299	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297000300	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297000301	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1008297000302	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1008297000303	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1008297000304	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1008297000305	Walker A/P-loop; other site
1008297000306	ATP binding site [chemical binding]; other site
1008297000307	Q-loop/lid; other site
1008297000308	ABC transporter signature motif; other site
1008297000309	Walker B; other site
1008297000310	D-loop; other site
1008297000311	H-loop/switch region; other site
1008297000312	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1008297000313	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297000314	dimer interface [polypeptide binding]; other site
1008297000315	conserved gate region; other site
1008297000316	putative PBP binding loops; other site
1008297000317	ABC-ATPase subunit interface; other site
1008297000318	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297000319	dimer interface [polypeptide binding]; other site
1008297000320	conserved gate region; other site
1008297000321	putative PBP binding loops; other site
1008297000322	ABC-ATPase subunit interface; other site
1008297000323	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1008297000324	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1008297000325	transcriptional regulator SgrR; Provisional; Region: PRK13626
1008297000326	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1008297000327	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1008297000328	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1008297000329	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1008297000330	substrate binding site [chemical binding]; other site
1008297000331	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1008297000332	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1008297000333	substrate binding site [chemical binding]; other site
1008297000334	ligand binding site [chemical binding]; other site
1008297000335	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1008297000336	tartrate dehydrogenase; Region: TTC; TIGR02089
1008297000337	2-isopropylmalate synthase; Validated; Region: PRK00915
1008297000338	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1008297000339	active site
1008297000340	catalytic residues [active]
1008297000341	metal binding site [ion binding]; metal-binding site
1008297000342	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1008297000343	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1008297000344	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297000345	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1008297000346	putative substrate binding pocket [chemical binding]; other site
1008297000347	putative dimerization interface [polypeptide binding]; other site
1008297000348	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1008297000349	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1008297000350	PYR/PP interface [polypeptide binding]; other site
1008297000351	dimer interface [polypeptide binding]; other site
1008297000352	TPP binding site [chemical binding]; other site
1008297000353	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1008297000354	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1008297000355	TPP-binding site [chemical binding]; other site
1008297000356	dimer interface [polypeptide binding]; other site
1008297000357	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1008297000358	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1008297000359	putative valine binding site [chemical binding]; other site
1008297000360	dimer interface [polypeptide binding]; other site
1008297000361	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1008297000362	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1008297000363	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297000364	DNA binding site [nucleotide binding]
1008297000365	domain linker motif; other site
1008297000366	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1008297000367	dimerization interface [polypeptide binding]; other site
1008297000368	ligand binding site [chemical binding]; other site
1008297000369	mraZ protein; Region: TIGR00242
1008297000370	MraZ protein; Region: MraZ; pfam02381
1008297000371	MraZ protein; Region: MraZ; pfam02381
1008297000372	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1008297000373	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1008297000374	cell division protein FtsL; Provisional; Region: PRK10772
1008297000375	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1008297000376	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1008297000377	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1008297000378	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1008297000379	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1008297000380	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1008297000381	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1008297000382	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1008297000383	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1008297000384	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1008297000385	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1008297000386	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1008297000387	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1008297000388	Mg++ binding site [ion binding]; other site
1008297000389	putative catalytic motif [active]
1008297000390	putative substrate binding site [chemical binding]; other site
1008297000391	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1008297000392	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1008297000393	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1008297000394	cell division protein FtsW; Provisional; Region: PRK10774
1008297000395	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1008297000396	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1008297000397	active site
1008297000398	homodimer interface [polypeptide binding]; other site
1008297000399	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1008297000400	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1008297000401	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1008297000402	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1008297000403	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1008297000404	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1008297000405	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1008297000406	cell division protein FtsQ; Provisional; Region: PRK10775
1008297000407	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1008297000408	Cell division protein FtsQ; Region: FtsQ; pfam03799
1008297000409	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1008297000410	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1008297000411	Cell division protein FtsA; Region: FtsA; pfam14450
1008297000412	cell division protein FtsZ; Validated; Region: PRK09330
1008297000413	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1008297000414	nucleotide binding site [chemical binding]; other site
1008297000415	SulA interaction site; other site
1008297000416	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
1008297000417	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1008297000418	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1008297000419	SecA regulator SecM; Provisional; Region: PRK02943
1008297000420	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1008297000421	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1008297000422	SEC-C motif; Region: SEC-C; pfam02810
1008297000423	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1008297000424	active site
1008297000425	8-oxo-dGMP binding site [chemical binding]; other site
1008297000426	nudix motif; other site
1008297000427	metal binding site [ion binding]; metal-binding site
1008297000428	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1008297000429	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
1008297000430	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1008297000431	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1008297000432	CoA-binding site [chemical binding]; other site
1008297000433	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1008297000434	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1008297000435	active site
1008297000436	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1008297000437	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1008297000438	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1008297000439	hypothetical protein; Provisional; Region: PRK10436
1008297000440	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1008297000441	Walker A motif; other site
1008297000442	ATP binding site [chemical binding]; other site
1008297000443	Walker B motif; other site
1008297000444	putative major pilin subunit; Provisional; Region: PRK10574
1008297000445	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1008297000446	Pilin (bacterial filament); Region: Pilin; pfam00114
1008297000447	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1008297000448	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1008297000449	dimerization interface [polypeptide binding]; other site
1008297000450	active site
1008297000451	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1008297000452	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1008297000453	amidase catalytic site [active]
1008297000454	Zn binding residues [ion binding]; other site
1008297000455	substrate binding site [chemical binding]; other site
1008297000456	regulatory protein AmpE; Provisional; Region: PRK10987
1008297000457	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1008297000458	active site
1008297000459	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1008297000460	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297000461	putative substrate translocation pore; other site
1008297000462	aromatic amino acid transporter; Provisional; Region: PRK10238
1008297000463	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1008297000464	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297000465	DNA-binding site [nucleotide binding]; DNA binding site
1008297000466	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1008297000467	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1008297000468	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1008297000469	dimer interface [polypeptide binding]; other site
1008297000470	TPP-binding site [chemical binding]; other site
1008297000471	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1008297000472	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1008297000473	E3 interaction surface; other site
1008297000474	lipoyl attachment site [posttranslational modification]; other site
1008297000475	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1008297000476	E3 interaction surface; other site
1008297000477	lipoyl attachment site [posttranslational modification]; other site
1008297000478	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1008297000479	E3 interaction surface; other site
1008297000480	lipoyl attachment site [posttranslational modification]; other site
1008297000481	e3 binding domain; Region: E3_binding; pfam02817
1008297000482	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1008297000483	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1008297000484	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1008297000485	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297000486	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1008297000487	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1008297000488	potential frameshift: common BLAST hit: gi|16763547|ref|NP_459162.1| outer membrane protein
1008297000489	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
1008297000490	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1008297000491	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1008297000492	substrate binding site [chemical binding]; other site
1008297000493	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1008297000494	substrate binding site [chemical binding]; other site
1008297000495	ligand binding site [chemical binding]; other site
1008297000496	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183
1008297000497	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
1008297000498	hypothetical protein; Provisional; Region: PRK05248
1008297000499	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
1008297000500	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1008297000501	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1008297000502	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
1008297000503	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1008297000504	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1008297000505	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297000506	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1008297000507	spermidine synthase; Provisional; Region: PRK00811
1008297000508	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297000509	S-adenosylmethionine binding site [chemical binding]; other site
1008297000510	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1008297000511	multicopper oxidase; Provisional; Region: PRK10965
1008297000512	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1008297000513	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1008297000514	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1008297000515	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1008297000516	Trp docking motif [polypeptide binding]; other site
1008297000517	putative active site [active]
1008297000518	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1008297000519	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1008297000520	active site
1008297000521	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1008297000522	active site clefts [active]
1008297000523	zinc binding site [ion binding]; other site
1008297000524	dimer interface [polypeptide binding]; other site
1008297000525	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1008297000526	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1008297000527	Walker A/P-loop; other site
1008297000528	ATP binding site [chemical binding]; other site
1008297000529	Q-loop/lid; other site
1008297000530	ABC transporter signature motif; other site
1008297000531	Walker B; other site
1008297000532	D-loop; other site
1008297000533	H-loop/switch region; other site
1008297000534	inner membrane transport permease; Provisional; Region: PRK15066
1008297000535	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1008297000536	putative fimbrial protein StiH; Provisional; Region: PRK15297
1008297000537	fimbrial outer membrane usher protein StiC; Provisional; Region: PRK15298
1008297000538	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297000539	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297000540	PapC C-terminal domain; Region: PapC_C; pfam13953
1008297000541	fimbrial chaperone protein StiB; Provisional; Region: PRK15299
1008297000542	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297000543	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297000544	fimbrial protein StiA; Provisional; Region: PRK15300
1008297000545	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1008297000546	active pocket/dimerization site; other site
1008297000547	active site
1008297000548	phosphorylation site [posttranslational modification]
1008297000549	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1008297000550	putative active site [active]
1008297000551	putative metal binding site [ion binding]; other site
1008297000552	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1008297000553	tetramerization interface [polypeptide binding]; other site
1008297000554	active site
1008297000555	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1008297000556	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1008297000557	active site
1008297000558	ATP-binding site [chemical binding]; other site
1008297000559	pantoate-binding site; other site
1008297000560	HXXH motif; other site
1008297000561	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1008297000562	oligomerization interface [polypeptide binding]; other site
1008297000563	active site
1008297000564	metal binding site [ion binding]; metal-binding site
1008297000565	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1008297000566	catalytic center binding site [active]
1008297000567	ATP binding site [chemical binding]; other site
1008297000568	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
1008297000569	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1008297000570	active site
1008297000571	NTP binding site [chemical binding]; other site
1008297000572	metal binding triad [ion binding]; metal-binding site
1008297000573	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1008297000574	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1008297000575	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1008297000576	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1008297000577	active site
1008297000578	nucleotide binding site [chemical binding]; other site
1008297000579	HIGH motif; other site
1008297000580	KMSKS motif; other site
1008297000581	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1008297000582	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1008297000583	2'-5' RNA ligase; Provisional; Region: PRK15124
1008297000584	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1008297000585	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1008297000586	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1008297000587	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1008297000588	ATP binding site [chemical binding]; other site
1008297000589	putative Mg++ binding site [ion binding]; other site
1008297000590	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297000591	nucleotide binding region [chemical binding]; other site
1008297000592	ATP-binding site [chemical binding]; other site
1008297000593	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1008297000594	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1008297000595	Transglycosylase; Region: Transgly; pfam00912
1008297000596	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1008297000597	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1008297000598	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1008297000599	N-terminal plug; other site
1008297000600	ligand-binding site [chemical binding]; other site
1008297000601	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1008297000602	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1008297000603	Walker A/P-loop; other site
1008297000604	ATP binding site [chemical binding]; other site
1008297000605	Q-loop/lid; other site
1008297000606	ABC transporter signature motif; other site
1008297000607	Walker B; other site
1008297000608	D-loop; other site
1008297000609	H-loop/switch region; other site
1008297000610	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1008297000611	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1008297000612	siderophore binding site; other site
1008297000613	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1008297000614	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1008297000615	ABC-ATPase subunit  interface; other site
1008297000616	dimer interface [polypeptide binding]; other site
1008297000617	putative PBP binding regions; other site
1008297000618	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1008297000619	ABC-ATPase subunit  interface; other site
1008297000620	dimer interface [polypeptide binding]; other site
1008297000621	putative PBP binding regions; other site
1008297000622	putative fimbrial subunit StfA; Provisional; Region: PRK15283
1008297000623	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1008297000624	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297000625	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297000626	PapC C-terminal domain; Region: PapC_C; pfam13953
1008297000627	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
1008297000628	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297000629	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297000630	putative minor fimbrial subunit StfE; Provisional; Region: PRK15286
1008297000631	putative minor fimbrial subunit StfF; Provisional; Region: PRK15287
1008297000632	putative minor fimbrial subunit StfG; Provisional; Region: PRK15288
1008297000633	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
1008297000634	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1008297000635	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1008297000636	inhibitor-cofactor binding pocket; inhibition site
1008297000637	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297000638	catalytic residue [active]
1008297000639	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1008297000640	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1008297000641	Cl- selectivity filter; other site
1008297000642	Cl- binding residues [ion binding]; other site
1008297000643	pore gating glutamate residue; other site
1008297000644	dimer interface [polypeptide binding]; other site
1008297000645	H+/Cl- coupling transport residue; other site
1008297000646	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1008297000647	hypothetical protein; Provisional; Region: PRK10578
1008297000648	UPF0126 domain; Region: UPF0126; pfam03458
1008297000649	UPF0126 domain; Region: UPF0126; pfam03458
1008297000650	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1008297000651	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1008297000652	cobalamin binding residues [chemical binding]; other site
1008297000653	putative BtuC binding residues; other site
1008297000654	dimer interface [polypeptide binding]; other site
1008297000655	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1008297000656	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1008297000657	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1008297000658	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1008297000659	Zn2+ binding site [ion binding]; other site
1008297000660	Mg2+ binding site [ion binding]; other site
1008297000661	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1008297000662	serine endoprotease; Provisional; Region: PRK10942
1008297000663	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1008297000664	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1008297000665	protein binding site [polypeptide binding]; other site
1008297000666	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1008297000667	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1008297000668	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1008297000669	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1008297000670	hypothetical protein; Provisional; Region: PRK13677
1008297000671	shikimate transporter; Provisional; Region: PRK09952
1008297000672	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297000673	putative substrate translocation pore; other site
1008297000674	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1008297000675	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1008297000676	trimer interface [polypeptide binding]; other site
1008297000677	active site
1008297000678	substrate binding site [chemical binding]; other site
1008297000679	CoA binding site [chemical binding]; other site
1008297000680	PII uridylyl-transferase; Provisional; Region: PRK05007
1008297000681	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1008297000682	metal binding triad; other site
1008297000683	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1008297000684	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1008297000685	Zn2+ binding site [ion binding]; other site
1008297000686	Mg2+ binding site [ion binding]; other site
1008297000687	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1008297000688	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1008297000689	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1008297000690	active site
1008297000691	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1008297000692	rRNA interaction site [nucleotide binding]; other site
1008297000693	S8 interaction site; other site
1008297000694	putative laminin-1 binding site; other site
1008297000695	elongation factor Ts; Provisional; Region: tsf; PRK09377
1008297000696	UBA/TS-N domain; Region: UBA; pfam00627
1008297000697	Elongation factor TS; Region: EF_TS; pfam00889
1008297000698	Elongation factor TS; Region: EF_TS; pfam00889
1008297000699	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1008297000700	putative nucleotide binding site [chemical binding]; other site
1008297000701	uridine monophosphate binding site [chemical binding]; other site
1008297000702	homohexameric interface [polypeptide binding]; other site
1008297000703	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1008297000704	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1008297000705	hinge region; other site
1008297000706	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1008297000707	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1008297000708	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1008297000709	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1008297000710	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1008297000711	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1008297000712	catalytic residue [active]
1008297000713	putative FPP diphosphate  binding site; other site
1008297000714	putative FPP binding hydrophobic cleft; other site
1008297000715	dimer interface [polypeptide binding]; other site
1008297000716	putative IPP diphosphate binding site; other site
1008297000717	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1008297000718	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1008297000719	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1008297000720	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1008297000721	active site
1008297000722	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1008297000723	protein binding site [polypeptide binding]; other site
1008297000724	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1008297000725	protein binding site [polypeptide binding]; other site
1008297000726	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1008297000727	putative substrate binding region [chemical binding]; other site
1008297000728	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1008297000729	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1008297000730	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1008297000731	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1008297000732	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1008297000733	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1008297000734	Surface antigen; Region: Bac_surface_Ag; pfam01103
1008297000735	periplasmic chaperone; Provisional; Region: PRK10780
1008297000736	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1008297000737	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1008297000738	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1008297000739	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1008297000740	trimer interface [polypeptide binding]; other site
1008297000741	active site
1008297000742	UDP-GlcNAc binding site [chemical binding]; other site
1008297000743	lipid binding site [chemical binding]; lipid-binding site
1008297000744	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1008297000745	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1008297000746	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1008297000747	active site
1008297000748	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1008297000749	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1008297000750	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1008297000751	RNA/DNA hybrid binding site [nucleotide binding]; other site
1008297000752	active site
1008297000753	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1008297000754	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1008297000755	putative active site [active]
1008297000756	putative PHP Thumb interface [polypeptide binding]; other site
1008297000757	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1008297000758	generic binding surface II; other site
1008297000759	generic binding surface I; other site
1008297000760	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1008297000761	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1008297000762	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1008297000763	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
1008297000764	putative sugar binding site [chemical binding]; other site
1008297000765	catalytic residues [active]
1008297000766	PKD domain; Region: PKD; pfam00801
1008297000767	potential frameshift: common BLAST hit: gi|379699455|ref|YP_005241183.1| lysine decarboxylase 2
1008297000768	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1008297000769	Orn/Lys/Arg decarboxylase, major domain; Region: OKR_DC_1; pfam01276
1008297000770	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1008297000771	homodimer interface [polypeptide binding]; other site
1008297000772	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297000773	catalytic residue [active]
1008297000774	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1008297000775	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1008297000776	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1008297000777	putative metal binding site [ion binding]; other site
1008297000778	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1008297000779	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1008297000780	Ligand Binding Site [chemical binding]; other site
1008297000781	TilS substrate binding domain; Region: TilS; pfam09179
1008297000782	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1008297000783	Modulator of Rho-dependent transcription termination (ROF); Region: ROF; cl09210
1008297000784	hypothetical protein; Provisional; Region: PRK04964
1008297000785	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1008297000786	hypothetical protein; Provisional; Region: PRK09256
1008297000787	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1008297000788	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1008297000789	NlpE N-terminal domain; Region: NlpE; pfam04170
1008297000790	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1008297000791	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1008297000792	dimer interface [polypeptide binding]; other site
1008297000793	motif 1; other site
1008297000794	active site
1008297000795	motif 2; other site
1008297000796	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1008297000797	putative deacylase active site [active]
1008297000798	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1008297000799	active site
1008297000800	motif 3; other site
1008297000801	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1008297000802	anticodon binding site; other site
1008297000803	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1008297000804	homodimer interaction site [polypeptide binding]; other site
1008297000805	cofactor binding site; other site
1008297000806	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1008297000807	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1008297000808	lipoprotein, YaeC family; Region: TIGR00363
1008297000809	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297000810	dimer interface [polypeptide binding]; other site
1008297000811	conserved gate region; other site
1008297000812	ABC-ATPase subunit interface; other site
1008297000813	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1008297000814	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1008297000815	Walker A/P-loop; other site
1008297000816	ATP binding site [chemical binding]; other site
1008297000817	Q-loop/lid; other site
1008297000818	ABC transporter signature motif; other site
1008297000819	Walker B; other site
1008297000820	D-loop; other site
1008297000821	H-loop/switch region; other site
1008297000822	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1008297000823	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1008297000824	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297000825	active site
1008297000826	motif I; other site
1008297000827	motif II; other site
1008297000828	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1008297000829	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1008297000830	active site
1008297000831	catalytic tetrad [active]
1008297000832	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297000833	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297000834	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
1008297000835	putative effector binding pocket; other site
1008297000836	dimerization interface [polypeptide binding]; other site
1008297000837	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1008297000838	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297000839	putative substrate translocation pore; other site
1008297000840	hypothetical protein; Provisional; Region: PRK05421
1008297000841	putative catalytic site [active]
1008297000842	putative metal binding site [ion binding]; other site
1008297000843	putative phosphate binding site [ion binding]; other site
1008297000844	putative catalytic site [active]
1008297000845	putative phosphate binding site [ion binding]; other site
1008297000846	putative metal binding site [ion binding]; other site
1008297000847	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1008297000848	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297000849	S-adenosylmethionine binding site [chemical binding]; other site
1008297000850	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1008297000851	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1008297000852	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1008297000853	catalytic residue [active]
1008297000854	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1008297000855	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1008297000856	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1008297000857	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1008297000858	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1008297000859	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297000860	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1008297000861	RNA/DNA hybrid binding site [nucleotide binding]; other site
1008297000862	active site
1008297000863	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1008297000864	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1008297000865	active site
1008297000866	catalytic site [active]
1008297000867	substrate binding site [chemical binding]; other site
1008297000868	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1008297000869	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1008297000870	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
1008297000871	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1008297000872	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1008297000873	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
1008297000874	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
1008297000875	ImpE protein; Region: ImpE; pfam07024
1008297000876	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1008297000877	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297000878	Walker A motif; other site
1008297000879	ATP binding site [chemical binding]; other site
1008297000880	Walker B motif; other site
1008297000881	arginine finger; other site
1008297000882	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297000883	Walker A motif; other site
1008297000884	ATP binding site [chemical binding]; other site
1008297000885	Walker B motif; other site
1008297000886	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1008297000887	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
1008297000888	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1008297000889	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1008297000890	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1008297000891	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
1008297000892	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1008297000893	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
1008297000894	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
1008297000895	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1008297000896	hypothetical protein; Provisional; Region: PRK08126
1008297000897	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
1008297000898	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1008297000899	ligand binding site [chemical binding]; other site
1008297000900	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1008297000901	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1008297000902	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1008297000903	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; cl01611
1008297000904	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4893
1008297000905	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501
1008297000906	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1008297000907	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1008297000908	Uncharacterized conserved protein [Function unknown]; Region: COG5435
1008297000909	potential frameshift: common BLAST hit: gi|378987690|ref|YP_005250854.1| putative RHS-like protein
1008297000910	PAAR motif; Region: PAAR_motif; pfam05488
1008297000911	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1008297000912	RHS Repeat; Region: RHS_repeat; cl11982
1008297000913	RHS Repeat; Region: RHS_repeat; pfam05593
1008297000914	RHS protein; Region: RHS; pfam03527
1008297000915	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1008297000916	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1008297000917	RHS protein; Region: RHS; pfam03527
1008297000918	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1008297000919	putative phosphotriesterase (pseudogene)
1008297000920	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
1008297000921	transposase (pseudogene)
1008297000922	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
1008297000923	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297000924	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297000925	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
1008297000926	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297000927	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297000928	PapC C-terminal domain; Region: PapC_C; pfam13953
1008297000929	putative pilin structural protein SafD; Provisional; Region: PRK15222
1008297000930	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1008297000931	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
1008297000932	putative active site [active]
1008297000933	putative metal binding site [ion binding]; other site
1008297000934	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297000935	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297000936	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297000937	dimerization interface [polypeptide binding]; other site
1008297000938	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1008297000939	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1008297000940	dimer interface [polypeptide binding]; other site
1008297000941	C-N hydrolase family amidase; Provisional; Region: PRK10438
1008297000942	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1008297000943	putative active site [active]
1008297000944	catalytic triad [active]
1008297000945	dimer interface [polypeptide binding]; other site
1008297000946	multimer interface [polypeptide binding]; other site
1008297000947	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1008297000948	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1008297000949	active site
1008297000950	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1008297000951	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1008297000952	dimer interface [polypeptide binding]; other site
1008297000953	active site
1008297000954	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1008297000955	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1008297000956	putative active site [active]
1008297000957	putative dimer interface [polypeptide binding]; other site
1008297000958	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1008297000959	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1008297000960	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1008297000961	active site
1008297000962	DNA polymerase IV; Validated; Region: PRK02406
1008297000963	DNA binding site [nucleotide binding]
1008297000964	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1008297000965	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1008297000966	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1008297000967	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1008297000968	metal binding site [ion binding]; metal-binding site
1008297000969	dimer interface [polypeptide binding]; other site
1008297000970	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1008297000971	active site
1008297000972	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1008297000973	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1008297000974	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1008297000975	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1008297000976	trimer interface [polypeptide binding]; other site
1008297000977	eyelet of channel; other site
1008297000978	gamma-glutamyl kinase; Provisional; Region: PRK05429
1008297000979	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1008297000980	nucleotide binding site [chemical binding]; other site
1008297000981	homotetrameric interface [polypeptide binding]; other site
1008297000982	putative phosphate binding site [ion binding]; other site
1008297000983	putative allosteric binding site; other site
1008297000984	PUA domain; Region: PUA; pfam01472
1008297000985	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1008297000986	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1008297000987	putative catalytic cysteine [active]
1008297000988	HTH-like domain; Region: HTH_21; pfam13276
1008297000989	Integrase core domain; Region: rve; pfam00665
1008297000990	Integrase core domain; Region: rve_2; pfam13333
1008297000991	glycerol dehydratase reactivation factor large subunit (pseudogene)
1008297000992	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
1008297000993	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1008297000994	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297000995	putative substrate translocation pore; other site
1008297000996	potential frameshift: common BLAST hit: gi|378987730|ref|YP_005250894.1| isopropylmalate isomerase large subunit
1008297000997	isopropylmalate isomerase large subunit; Provisional; Region: PRK12466
1008297000998	substrate binding site [chemical binding]; other site
1008297000999	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
1008297001000	3-isopropylmalate dehydratase small subunit [Amino acid transport and metabolism]; Region: LeuD; COG0066
1008297001001	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1008297001002	hypothetical protein; Provisional; Region: PRK14812
1008297001003	substrate binding site [chemical binding]; other site
1008297001004	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1008297001005	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1008297001006	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1008297001007	transcriptional activator TtdR; Provisional; Region: PRK09801
1008297001008	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297001009	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1008297001010	putative effector binding pocket; other site
1008297001011	putative dimerization interface [polypeptide binding]; other site
1008297001012	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297001013	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297001014	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
1008297001015	fimbrial outer membrane usher protein StbC; Provisional; Region: PRK15248
1008297001016	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297001017	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297001018	PapC C-terminal domain; Region: PapC_C; pfam13953
1008297001019	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297001020	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297001021	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1008297001022	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1008297001023	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1008297001024	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297001025	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1008297001026	DNA binding site [nucleotide binding]
1008297001027	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1008297001028	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1008297001029	DNA binding residues [nucleotide binding]
1008297001030	dimerization interface [polypeptide binding]; other site
1008297001031	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1008297001032	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1008297001033	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1008297001034	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1008297001035	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1008297001036	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297001037	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1008297001038	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1008297001039	metal-binding site [ion binding]
1008297001040	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1008297001041	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297001042	motif II; other site
1008297001043	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
1008297001044	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1008297001045	DNA binding residues [nucleotide binding]
1008297001046	dimer interface [polypeptide binding]; other site
1008297001047	copper binding site [ion binding]; other site
1008297001048	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1008297001049	metal-binding site [ion binding]
1008297001050	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297001051	putative sialic acid transporter; Region: 2A0112; TIGR00891
1008297001052	putative substrate translocation pore; other site
1008297001053	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1008297001054	DNA methylase; Region: N6_N4_Mtase; cl17433
1008297001055	DNA methylase; Region: N6_N4_Mtase; pfam01555
1008297001056	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
1008297001057	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1008297001058	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1008297001059	VRR-NUC domain; Region: VRR_NUC; pfam08774
1008297001060	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1008297001061	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1008297001062	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1008297001063	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1008297001064	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1008297001065	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1008297001066	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1008297001067	N-terminal plug; other site
1008297001068	ligand-binding site [chemical binding]; other site
1008297001069	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
1008297001070	hypothetical protein; Provisional; Region: PRK09929
1008297001071	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1008297001072	Propionate catabolism activator; Region: PrpR_N; pfam06506
1008297001073	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297001074	Walker A motif; other site
1008297001075	ATP binding site [chemical binding]; other site
1008297001076	Walker B motif; other site
1008297001077	arginine finger; other site
1008297001078	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1008297001079	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1008297001080	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1008297001081	tetramer interface [polypeptide binding]; other site
1008297001082	active site
1008297001083	Mg2+/Mn2+ binding site [ion binding]; other site
1008297001084	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1008297001085	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
1008297001086	dimer interface [polypeptide binding]; other site
1008297001087	active site
1008297001088	citrylCoA binding site [chemical binding]; other site
1008297001089	oxalacetate/citrate binding site [chemical binding]; other site
1008297001090	coenzyme A binding site [chemical binding]; other site
1008297001091	catalytic triad [active]
1008297001092	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1008297001093	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1008297001094	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
1008297001095	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1008297001096	acyl-activating enzyme (AAE) consensus motif; other site
1008297001097	AMP binding site [chemical binding]; other site
1008297001098	active site
1008297001099	CoA binding site [chemical binding]; other site
1008297001100	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1008297001101	dimer interface [polypeptide binding]; other site
1008297001102	active site
1008297001103	Schiff base residues; other site
1008297001104	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
1008297001105	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1008297001106	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1008297001107	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1008297001108	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1008297001109	ligand binding site [chemical binding]; other site
1008297001110	flexible hinge region; other site
1008297001111	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1008297001112	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1008297001113	microcin B17 transporter; Reviewed; Region: PRK11098
1008297001114	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1008297001115	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
1008297001116	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
1008297001117	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1008297001118	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1008297001119	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1008297001120	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
1008297001121	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
1008297001122	drug efflux system protein MdtG; Provisional; Region: PRK09874
1008297001123	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297001124	putative substrate translocation pore; other site
1008297001125	anti-RssB factor; Provisional; Region: PRK10244
1008297001126	hypothetical protein; Provisional; Region: PRK11505
1008297001127	psiF repeat; Region: PsiF_repeat; pfam07769
1008297001128	psiF repeat; Region: PsiF_repeat; pfam07769
1008297001129	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
1008297001130	MASE2 domain; Region: MASE2; pfam05230
1008297001131	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1008297001132	metal binding site [ion binding]; metal-binding site
1008297001133	active site
1008297001134	I-site; other site
1008297001135	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1008297001136	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1008297001137	hypothetical protein; Validated; Region: PRK00124
1008297001138	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1008297001139	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1008297001140	ADP binding site [chemical binding]; other site
1008297001141	magnesium binding site [ion binding]; other site
1008297001142	putative shikimate binding site; other site
1008297001143	hypothetical protein; Provisional; Region: PRK10380
1008297001144	hypothetical protein; Provisional; Region: PRK10481
1008297001145	hypothetical protein; Provisional; Region: PRK10579
1008297001146	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
1008297001147	fructokinase; Reviewed; Region: PRK09557
1008297001148	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1008297001149	nucleotide binding site [chemical binding]; other site
1008297001150	MFS transport protein AraJ; Provisional; Region: PRK10091
1008297001151	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297001152	putative substrate translocation pore; other site
1008297001153	exonuclease subunit SbcC; Provisional; Region: PRK10246
1008297001154	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297001155	Walker A/P-loop; other site
1008297001156	ATP binding site [chemical binding]; other site
1008297001157	Q-loop/lid; other site
1008297001158	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297001159	ABC transporter signature motif; other site
1008297001160	Walker B; other site
1008297001161	D-loop; other site
1008297001162	H-loop/switch region; other site
1008297001163	exonuclease subunit SbcD; Provisional; Region: PRK10966
1008297001164	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1008297001165	active site
1008297001166	metal binding site [ion binding]; metal-binding site
1008297001167	DNA binding site [nucleotide binding]
1008297001168	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1008297001169	transcriptional regulator PhoB; Provisional; Region: PRK10161
1008297001170	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297001171	active site
1008297001172	phosphorylation site [posttranslational modification]
1008297001173	intermolecular recognition site; other site
1008297001174	dimerization interface [polypeptide binding]; other site
1008297001175	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297001176	DNA binding site [nucleotide binding]
1008297001177	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1008297001178	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1008297001179	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1008297001180	putative active site [active]
1008297001181	heme pocket [chemical binding]; other site
1008297001182	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297001183	dimer interface [polypeptide binding]; other site
1008297001184	phosphorylation site [posttranslational modification]
1008297001185	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297001186	ATP binding site [chemical binding]; other site
1008297001187	Mg2+ binding site [ion binding]; other site
1008297001188	G-X-G motif; other site
1008297001189	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1008297001190	putative proline-specific permease; Provisional; Region: proY; PRK10580
1008297001191	maltodextrin glucosidase; Provisional; Region: PRK10785
1008297001192	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1008297001193	homodimer interface [polypeptide binding]; other site
1008297001194	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1008297001195	active site
1008297001196	homodimer interface [polypeptide binding]; other site
1008297001197	catalytic site [active]
1008297001198	peroxidase; Provisional; Region: PRK15000
1008297001199	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1008297001200	dimer interface [polypeptide binding]; other site
1008297001201	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1008297001202	catalytic triad [active]
1008297001203	peroxidatic and resolving cysteines [active]
1008297001204	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1008297001205	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1008297001206	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1008297001207	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1008297001208	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1008297001209	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1008297001210	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1008297001211	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1008297001212	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1008297001213	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1008297001214	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1008297001215	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1008297001216	Protein export membrane protein; Region: SecD_SecF; pfam02355
1008297001217	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
1008297001218	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1008297001219	Predicted transcriptional regulator [Transcription]; Region: COG2378
1008297001220	HTH domain; Region: HTH_11; pfam08279
1008297001221	WYL domain; Region: WYL; pfam13280
1008297001222	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1008297001223	active site
1008297001224	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1008297001225	hypothetical protein; Provisional; Region: PRK11530
1008297001226	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1008297001227	ATP cone domain; Region: ATP-cone; pfam03477
1008297001228	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1008297001229	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1008297001230	catalytic motif [active]
1008297001231	Zn binding site [ion binding]; other site
1008297001232	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1008297001233	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1008297001234	homopentamer interface [polypeptide binding]; other site
1008297001235	active site
1008297001236	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1008297001237	putative RNA binding site [nucleotide binding]; other site
1008297001238	thiamine monophosphate kinase; Provisional; Region: PRK05731
1008297001239	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1008297001240	ATP binding site [chemical binding]; other site
1008297001241	dimerization interface [polypeptide binding]; other site
1008297001242	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1008297001243	tetramer interfaces [polypeptide binding]; other site
1008297001244	binuclear metal-binding site [ion binding]; other site
1008297001245	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1008297001246	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1008297001247	active site
1008297001248	catalytic tetrad [active]
1008297001249	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1008297001250	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1008297001251	TPP-binding site; other site
1008297001252	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1008297001253	PYR/PP interface [polypeptide binding]; other site
1008297001254	dimer interface [polypeptide binding]; other site
1008297001255	TPP binding site [chemical binding]; other site
1008297001256	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1008297001257	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1008297001258	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1008297001259	substrate binding pocket [chemical binding]; other site
1008297001260	chain length determination region; other site
1008297001261	substrate-Mg2+ binding site; other site
1008297001262	catalytic residues [active]
1008297001263	aspartate-rich region 1; other site
1008297001264	active site lid residues [active]
1008297001265	aspartate-rich region 2; other site
1008297001266	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1008297001267	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1008297001268	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1008297001269	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1008297001270	Ligand Binding Site [chemical binding]; other site
1008297001271	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1008297001272	active site residue [active]
1008297001273	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1008297001274	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297001275	dimer interface [polypeptide binding]; other site
1008297001276	conserved gate region; other site
1008297001277	ABC-ATPase subunit interface; other site
1008297001278	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
1008297001279	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297001280	dimer interface [polypeptide binding]; other site
1008297001281	conserved gate region; other site
1008297001282	putative PBP binding loops; other site
1008297001283	ABC-ATPase subunit interface; other site
1008297001284	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
1008297001285	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297001286	Walker A/P-loop; other site
1008297001287	ATP binding site [chemical binding]; other site
1008297001288	Q-loop/lid; other site
1008297001289	ABC transporter signature motif; other site
1008297001290	Walker B; other site
1008297001291	D-loop; other site
1008297001292	H-loop/switch region; other site
1008297001293	TOBE domain; Region: TOBE_2; pfam08402
1008297001294	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
1008297001295	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1008297001296	transcriptional regulator protein; Region: phnR; TIGR03337
1008297001297	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297001298	DNA-binding site [nucleotide binding]; DNA binding site
1008297001299	UTRA domain; Region: UTRA; pfam07702
1008297001300	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
1008297001301	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1008297001302	catalytic residue [active]
1008297001303	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
1008297001304	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297001305	motif II; other site
1008297001306	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1008297001307	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1008297001308	conserved cys residue [active]
1008297001309	2-dehydropantoate 2-reductase; Region: apbA_panE; TIGR00745
1008297001310	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1008297001311	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1008297001312	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1008297001313	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1008297001314	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297001315	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1008297001316	putative substrate translocation pore; other site
1008297001317	Sel1-like repeats; Region: SEL1; smart00671
1008297001318	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1008297001319	Sel1 repeat; Region: Sel1; pfam08238
1008297001320	Sel1-like repeats; Region: SEL1; smart00671
1008297001321	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1008297001322	Sel1-like repeats; Region: SEL1; smart00671
1008297001323	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1008297001324	Sel1-like repeats; Region: SEL1; smart00671
1008297001325	Sel1-like repeats; Region: SEL1; smart00671
1008297001326	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1008297001327	UbiA prenyltransferase family; Region: UbiA; pfam01040
1008297001328	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1008297001329	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1008297001330	Subunit I/III interface [polypeptide binding]; other site
1008297001331	Subunit III/IV interface [polypeptide binding]; other site
1008297001332	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1008297001333	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1008297001334	D-pathway; other site
1008297001335	Putative ubiquinol binding site [chemical binding]; other site
1008297001336	Low-spin heme (heme b) binding site [chemical binding]; other site
1008297001337	Putative water exit pathway; other site
1008297001338	Binuclear center (heme o3/CuB) [ion binding]; other site
1008297001339	K-pathway; other site
1008297001340	Putative proton exit pathway; other site
1008297001341	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1008297001342	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1008297001343	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1008297001344	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1008297001345	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297001346	putative substrate translocation pore; other site
1008297001347	hypothetical protein; Provisional; Region: PRK11627
1008297001348	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1008297001349	transcriptional regulator BolA; Provisional; Region: PRK11628
1008297001350	trigger factor; Provisional; Region: tig; PRK01490
1008297001351	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1008297001352	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1008297001353	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1008297001354	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1008297001355	oligomer interface [polypeptide binding]; other site
1008297001356	active site residues [active]
1008297001357	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1008297001358	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1008297001359	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297001360	Walker A motif; other site
1008297001361	ATP binding site [chemical binding]; other site
1008297001362	Walker B motif; other site
1008297001363	Iron permease FTR1 family; Region: FTR1; cl00475
1008297001364	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1008297001365	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1008297001366	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1008297001367	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1008297001368	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297001369	Walker A motif; other site
1008297001370	ATP binding site [chemical binding]; other site
1008297001371	Walker B motif; other site
1008297001372	arginine finger; other site
1008297001373	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1008297001374	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1008297001375	IHF dimer interface [polypeptide binding]; other site
1008297001376	IHF - DNA interface [nucleotide binding]; other site
1008297001377	periplasmic folding chaperone; Provisional; Region: PRK10788
1008297001378	SurA N-terminal domain; Region: SurA_N_3; cl07813
1008297001379	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1008297001380	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1008297001381	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1008297001382	active site
1008297001383	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1008297001384	Ligand Binding Site [chemical binding]; other site
1008297001385	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1008297001386	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1008297001387	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1008297001388	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1008297001389	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297001390	active site
1008297001391	motif I; other site
1008297001392	motif II; other site
1008297001393	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1008297001394	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1008297001395	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1008297001396	catalytic residue [active]
1008297001397	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1008297001398	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1008297001399	putative DNA binding site [nucleotide binding]; other site
1008297001400	putative Zn2+ binding site [ion binding]; other site
1008297001401	AsnC family; Region: AsnC_trans_reg; pfam01037
1008297001402	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1008297001403	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1008297001404	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297001405	Walker A/P-loop; other site
1008297001406	ATP binding site [chemical binding]; other site
1008297001407	Q-loop/lid; other site
1008297001408	ABC transporter signature motif; other site
1008297001409	Walker B; other site
1008297001410	D-loop; other site
1008297001411	H-loop/switch region; other site
1008297001412	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1008297001413	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1008297001414	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297001415	Walker A/P-loop; other site
1008297001416	ATP binding site [chemical binding]; other site
1008297001417	Q-loop/lid; other site
1008297001418	ABC transporter signature motif; other site
1008297001419	Walker B; other site
1008297001420	D-loop; other site
1008297001421	H-loop/switch region; other site
1008297001422	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1008297001423	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1008297001424	ammonium transporter; Provisional; Region: PRK10666
1008297001425	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1008297001426	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1008297001427	active site
1008297001428	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1008297001429	catalytic triad [active]
1008297001430	dimer interface [polypeptide binding]; other site
1008297001431	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1008297001432	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1008297001433	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1008297001434	DNA binding site [nucleotide binding]
1008297001435	active site
1008297001436	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1008297001437	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1008297001438	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297001439	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1008297001440	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1008297001441	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1008297001442	maltose O-acetyltransferase; Provisional; Region: PRK10092
1008297001443	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1008297001444	active site
1008297001445	substrate binding site [chemical binding]; other site
1008297001446	trimer interface [polypeptide binding]; other site
1008297001447	CoA binding site [chemical binding]; other site
1008297001448	gene expression modulator; Provisional; Region: PRK10945
1008297001449	Hha toxicity attenuator; Provisional; Region: PRK10667
1008297001450	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1008297001451	Protein export membrane protein; Region: SecD_SecF; cl14618
1008297001452	Protein export membrane protein; Region: SecD_SecF; cl14618
1008297001453	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1008297001454	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297001455	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1008297001456	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297001457	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1008297001458	hypothetical protein; Provisional; Region: PRK11281
1008297001459	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1008297001460	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
1008297001461	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1008297001462	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1008297001463	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1008297001464	hypothetical protein; Provisional; Region: PRK11038
1008297001465	primosomal replication protein N''; Provisional; Region: PRK10093
1008297001466	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1008297001467	active site
1008297001468	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1008297001469	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297001470	Walker A motif; other site
1008297001471	ATP binding site [chemical binding]; other site
1008297001472	Walker B motif; other site
1008297001473	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1008297001474	arginine finger; other site
1008297001475	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1008297001476	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1008297001477	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1008297001478	hypothetical protein; Validated; Region: PRK00153
1008297001479	recombination protein RecR; Reviewed; Region: recR; PRK00076
1008297001480	RecR protein; Region: RecR; pfam02132
1008297001481	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1008297001482	putative active site [active]
1008297001483	putative metal-binding site [ion binding]; other site
1008297001484	tetramer interface [polypeptide binding]; other site
1008297001485	heat shock protein 90; Provisional; Region: PRK05218
1008297001486	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297001487	ATP binding site [chemical binding]; other site
1008297001488	Mg2+ binding site [ion binding]; other site
1008297001489	G-X-G motif; other site
1008297001490	adenylate kinase; Reviewed; Region: adk; PRK00279
1008297001491	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1008297001492	AMP-binding site [chemical binding]; other site
1008297001493	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1008297001494	ferrochelatase; Reviewed; Region: hemH; PRK00035
1008297001495	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1008297001496	C-terminal domain interface [polypeptide binding]; other site
1008297001497	active site
1008297001498	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1008297001499	active site
1008297001500	N-terminal domain interface [polypeptide binding]; other site
1008297001501	acetyl esterase; Provisional; Region: PRK10162
1008297001502	inosine/guanosine kinase; Provisional; Region: PRK15074
1008297001503	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297001504	putative cation:proton antiport protein; Provisional; Region: PRK10669
1008297001505	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1008297001506	TrkA-N domain; Region: TrkA_N; pfam02254
1008297001507	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297001508	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1008297001509	putative substrate translocation pore; other site
1008297001510	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1008297001511	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1008297001512	active site
1008297001513	metal binding site [ion binding]; metal-binding site
1008297001514	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1008297001515	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1008297001516	putative deacylase active site [active]
1008297001517	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
1008297001518	potential frameshift: common BLAST hit: gi|378698458|ref|YP_005180415.1| secreted protein
1008297001519	copper exporting ATPase; Provisional; Region: copA; PRK10671
1008297001520	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1008297001521	metal-binding site [ion binding]
1008297001522	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1008297001523	metal-binding site [ion binding]
1008297001524	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1008297001525	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297001526	motif II; other site
1008297001527	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1008297001528	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1008297001529	DNA binding residues [nucleotide binding]
1008297001530	dimer interface [polypeptide binding]; other site
1008297001531	copper binding site [ion binding]; other site
1008297001532	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1008297001533	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1008297001534	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1008297001535	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1008297001536	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1008297001537	Walker A/P-loop; other site
1008297001538	ATP binding site [chemical binding]; other site
1008297001539	Q-loop/lid; other site
1008297001540	ABC transporter signature motif; other site
1008297001541	Walker B; other site
1008297001542	D-loop; other site
1008297001543	H-loop/switch region; other site
1008297001544	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1008297001545	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1008297001546	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1008297001547	oxidoreductase; Provisional; Region: PRK08017
1008297001548	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1008297001549	NADP binding site [chemical binding]; other site
1008297001550	active site
1008297001551	steroid binding site; other site
1008297001552	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1008297001553	active site
1008297001554	catalytic triad [active]
1008297001555	oxyanion hole [active]
1008297001556	switch loop; other site
1008297001557	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1008297001558	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1008297001559	Walker A/P-loop; other site
1008297001560	ATP binding site [chemical binding]; other site
1008297001561	Q-loop/lid; other site
1008297001562	ABC transporter signature motif; other site
1008297001563	Walker B; other site
1008297001564	D-loop; other site
1008297001565	H-loop/switch region; other site
1008297001566	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1008297001567	FtsX-like permease family; Region: FtsX; pfam02687
1008297001568	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1008297001569	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1008297001570	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1008297001571	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1008297001572	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
1008297001573	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1008297001574	Walker A/P-loop; other site
1008297001575	ATP binding site [chemical binding]; other site
1008297001576	Q-loop/lid; other site
1008297001577	ABC transporter signature motif; other site
1008297001578	Walker B; other site
1008297001579	D-loop; other site
1008297001580	H-loop/switch region; other site
1008297001581	NIL domain; Region: NIL; pfam09383
1008297001582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297001583	dimer interface [polypeptide binding]; other site
1008297001584	conserved gate region; other site
1008297001585	ABC-ATPase subunit interface; other site
1008297001586	Predicted ATPase [General function prediction only]; Region: COG2603
1008297001587	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1008297001588	active site residue [active]
1008297001589	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1008297001590	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297001591	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297001592	dimerization interface [polypeptide binding]; other site
1008297001593	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
1008297001594	ureidoglycolate hydrolase; Provisional; Region: PRK03606
1008297001595	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
1008297001596	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1008297001597	Bacterial transcriptional regulator; Region: IclR; pfam01614
1008297001598	glyoxylate carboligase; Provisional; Region: PRK11269
1008297001599	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1008297001600	PYR/PP interface [polypeptide binding]; other site
1008297001601	dimer interface [polypeptide binding]; other site
1008297001602	TPP binding site [chemical binding]; other site
1008297001603	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1008297001604	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
1008297001605	TPP-binding site [chemical binding]; other site
1008297001606	hydroxypyruvate isomerase; Provisional; Region: PRK09997
1008297001607	tartronate semialdehyde reductase; Provisional; Region: PRK15059
1008297001608	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1008297001609	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297001610	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1008297001611	putative substrate translocation pore; other site
1008297001612	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily, YbbW-like; solute-binding domain; Region: SLC-NCS1sbd_YbbW-like; cd11485
1008297001613	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1008297001614	Na binding site [ion binding]; other site
1008297001615	putative substrate binding site [chemical binding]; other site
1008297001616	allantoinase; Provisional; Region: PRK08044
1008297001617	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
1008297001618	active site
1008297001619	putative uracil/xanthine transporter; Provisional; Region: PRK11412
1008297001620	glycerate kinase II; Provisional; Region: PRK09932
1008297001621	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
1008297001622	Mif2/CENP-C like; Region: Mif2; pfam11699
1008297001623	Cupin domain; Region: Cupin_2; pfam07883
1008297001624	allantoate amidohydrolase; Region: AllC; TIGR03176
1008297001625	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1008297001626	active site
1008297001627	metal binding site [ion binding]; metal-binding site
1008297001628	dimer interface [polypeptide binding]; other site
1008297001629	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
1008297001630	membrane protein FdrA; Validated; Region: PRK06091
1008297001631	CoA binding domain; Region: CoA_binding; pfam02629
1008297001632	CoA-ligase; Region: Ligase_CoA; pfam00549
1008297001633	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1008297001634	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1008297001635	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1008297001636	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1008297001637	putative substrate binding site [chemical binding]; other site
1008297001638	nucleotide binding site [chemical binding]; other site
1008297001639	nucleotide binding site [chemical binding]; other site
1008297001640	homodimer interface [polypeptide binding]; other site
1008297001641	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1008297001642	ATP-grasp domain; Region: ATP-grasp; pfam02222
1008297001643	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1008297001644	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1008297001645	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1008297001646	putative active site [active]
1008297001647	putative metal binding site [ion binding]; other site
1008297001648	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1008297001649	substrate binding site [chemical binding]; other site
1008297001650	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1008297001651	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1008297001652	active site
1008297001653	HIGH motif; other site
1008297001654	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1008297001655	KMSKS motif; other site
1008297001656	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1008297001657	tRNA binding surface [nucleotide binding]; other site
1008297001658	anticodon binding site; other site
1008297001659	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4727
1008297001660	Uncharacterized protein conserved in bacteria (DUF2145); Region: DUF2145; pfam09916
1008297001661	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1008297001662	ribosome-associated protein; Provisional; Region: PRK11507
1008297001663	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1008297001664	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1008297001665	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1008297001666	homodimer interface [polypeptide binding]; other site
1008297001667	NADP binding site [chemical binding]; other site
1008297001668	substrate binding site [chemical binding]; other site
1008297001669	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
1008297001670	fimbrial protein FimI; Provisional; Region: PRK15200
1008297001671	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1008297001672	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297001673	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297001674	outer membrane usher protein FimD; Provisional; Region: PRK15198
1008297001675	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297001676	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297001677	PapC C-terminal domain; Region: PapC_C; pfam13953
1008297001678	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
1008297001679	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
1008297001680	transcriptional regulator FimZ; Provisional; Region: PRK09935
1008297001681	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297001682	active site
1008297001683	phosphorylation site [posttranslational modification]
1008297001684	intermolecular recognition site; other site
1008297001685	dimerization interface [polypeptide binding]; other site
1008297001686	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297001687	DNA binding residues [nucleotide binding]
1008297001688	dimerization interface [polypeptide binding]; other site
1008297001689	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
1008297001690	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297001691	DNA binding residues [nucleotide binding]
1008297001692	dimerization interface [polypeptide binding]; other site
1008297001693	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1008297001694	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1008297001695	Ligand binding site; other site
1008297001696	Putative Catalytic site; other site
1008297001697	DXD motif; other site
1008297001698	Predicted membrane protein [Function unknown]; Region: COG2246
1008297001699	GtrA-like protein; Region: GtrA; pfam04138
1008297001700	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297001701	ATP binding site [chemical binding]; other site
1008297001702	Mg2+ binding site [ion binding]; other site
1008297001703	G-X-G motif; other site
1008297001704	cation efflux protein (pseudogene)
1008297001705	Cupin; Region: Cupin_6; pfam12852
1008297001706	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1008297001707	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297001708	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297001709	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
1008297001710	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297001711	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1008297001712	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1008297001713	Predicted membrane protein [Function unknown]; Region: COG3059
1008297001714	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
1008297001715	phenylalanine transporter; Provisional; Region: PRK10249
1008297001716	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1008297001717	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1008297001718	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1008297001719	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1008297001720	active site
1008297001721	oxyanion hole [active]
1008297001722	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1008297001723	catalytic triad [active]
1008297001724	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1008297001725	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1008297001726	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297001727	ATP binding site [chemical binding]; other site
1008297001728	Walker B motif; other site
1008297001729	arginine finger; other site
1008297001730	Transcriptional antiterminator [Transcription]; Region: COG3933
1008297001731	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1008297001732	active pocket/dimerization site; other site
1008297001733	active site
1008297001734	phosphorylation site [posttranslational modification]
1008297001735	PRD domain; Region: PRD; pfam00874
1008297001736	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1008297001737	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1008297001738	putative active site [active]
1008297001739	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1008297001740	dimer interface [polypeptide binding]; other site
1008297001741	active site
1008297001742	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1008297001743	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1008297001744	dimer interface [polypeptide binding]; other site
1008297001745	active site
1008297001746	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1008297001747	dimer interface [polypeptide binding]; other site
1008297001748	active site
1008297001749	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1008297001750	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1008297001751	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1008297001752	active site
1008297001753	phosphorylation site [posttranslational modification]
1008297001754	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1008297001755	active pocket/dimerization site; other site
1008297001756	active site
1008297001757	phosphorylation site [posttranslational modification]
1008297001758	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1008297001759	dimer interface [polypeptide binding]; other site
1008297001760	FMN binding site [chemical binding]; other site
1008297001761	hypothetical protein; Provisional; Region: PRK10250
1008297001762	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1008297001763	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297001764	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1008297001765	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297001766	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1008297001767	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
1008297001768	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
1008297001769	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
1008297001770	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1008297001771	outer membrane receptor FepA; Provisional; Region: PRK13524
1008297001772	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1008297001773	N-terminal plug; other site
1008297001774	ligand-binding site [chemical binding]; other site
1008297001775	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1008297001776	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1008297001777	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1008297001778	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
1008297001779	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1008297001780	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1008297001781	acyl-activating enzyme (AAE) consensus motif; other site
1008297001782	AMP binding site [chemical binding]; other site
1008297001783	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1008297001784	LPS O-antigen length regulator; Provisional; Region: PRK10381
1008297001785	Chain length determinant protein; Region: Wzz; pfam02706
1008297001786	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1008297001787	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1008297001788	Walker A/P-loop; other site
1008297001789	ATP binding site [chemical binding]; other site
1008297001790	Q-loop/lid; other site
1008297001791	ABC transporter signature motif; other site
1008297001792	Walker B; other site
1008297001793	D-loop; other site
1008297001794	H-loop/switch region; other site
1008297001795	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1008297001796	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1008297001797	ABC-ATPase subunit  interface; other site
1008297001798	dimer interface [polypeptide binding]; other site
1008297001799	putative PBP binding regions; other site
1008297001800	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1008297001801	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1008297001802	ABC-ATPase subunit  interface; other site
1008297001803	dimer interface [polypeptide binding]; other site
1008297001804	putative PBP binding regions; other site
1008297001805	enterobactin exporter EntS; Provisional; Region: PRK10489
1008297001806	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297001807	putative substrate translocation pore; other site
1008297001808	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
1008297001809	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1008297001810	siderophore binding site; other site
1008297001811	isochorismate synthase EntC; Provisional; Region: PRK15016
1008297001812	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1008297001813	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
1008297001814	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1008297001815	acyl-activating enzyme (AAE) consensus motif; other site
1008297001816	active site
1008297001817	AMP binding site [chemical binding]; other site
1008297001818	substrate binding site [chemical binding]; other site
1008297001819	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1008297001820	hydrophobic substrate binding pocket; other site
1008297001821	Isochorismatase family; Region: Isochorismatase; pfam00857
1008297001822	active site
1008297001823	conserved cis-peptide bond; other site
1008297001824	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1008297001825	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1008297001826	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1008297001827	putative NAD(P) binding site [chemical binding]; other site
1008297001828	active site
1008297001829	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1008297001830	CoenzymeA binding site [chemical binding]; other site
1008297001831	subunit interaction site [polypeptide binding]; other site
1008297001832	PHB binding site; other site
1008297001833	carbon starvation protein A; Provisional; Region: PRK15015
1008297001834	Carbon starvation protein CstA; Region: CstA; pfam02554
1008297001835	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1008297001836	Uncharacterized small protein [Function unknown]; Region: COG2879
1008297001837	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1008297001838	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1008297001839	putative active site [active]
1008297001840	metal binding site [ion binding]; metal-binding site
1008297001841	methionine aminotransferase; Validated; Region: PRK09082
1008297001842	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297001843	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297001844	homodimer interface [polypeptide binding]; other site
1008297001845	catalytic residue [active]
1008297001846	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1008297001847	ParB-like nuclease domain; Region: ParBc; pfam02195
1008297001848	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1008297001849	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1008297001850	Active Sites [active]
1008297001851	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1008297001852	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1008297001853	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297001854	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297001855	dimerization interface [polypeptide binding]; other site
1008297001856	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1008297001857	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1008297001858	dimerization domain [polypeptide binding]; other site
1008297001859	dimer interface [polypeptide binding]; other site
1008297001860	catalytic residues [active]
1008297001861	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1008297001862	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1008297001863	dimer interface [polypeptide binding]; other site
1008297001864	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1008297001865	catalytic triad [active]
1008297001866	peroxidatic and resolving cysteines [active]
1008297001867	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1008297001868	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1008297001869	catalytic residue [active]
1008297001870	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1008297001871	catalytic residues [active]
1008297001872	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1008297001873	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297001874	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1008297001875	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
1008297001876	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
1008297001877	putative molybdopterin cofactor binding site [chemical binding]; other site
1008297001878	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
1008297001879	molybdopterin cofactor binding site; other site
1008297001880	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1008297001881	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1008297001882	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1008297001883	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1008297001884	Ligand Binding Site [chemical binding]; other site
1008297001885	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1008297001886	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1008297001887	NAD binding site [chemical binding]; other site
1008297001888	catalytic Zn binding site [ion binding]; other site
1008297001889	structural Zn binding site [ion binding]; other site
1008297001890	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1008297001891	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1008297001892	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1008297001893	B1 nucleotide binding pocket [chemical binding]; other site
1008297001894	B2 nucleotide binding pocket [chemical binding]; other site
1008297001895	CAS motifs; other site
1008297001896	active site
1008297001897	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1008297001898	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1008297001899	transmembrane helices; other site
1008297001900	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
1008297001901	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1008297001902	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1008297001903	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1008297001904	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1008297001905	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1008297001906	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1008297001907	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1008297001908	putative active site [active]
1008297001909	(T/H)XGH motif; other site
1008297001910	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
1008297001911	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1008297001912	putative active site [active]
1008297001913	heme pocket [chemical binding]; other site
1008297001914	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297001915	ATP binding site [chemical binding]; other site
1008297001916	Mg2+ binding site [ion binding]; other site
1008297001917	G-X-G motif; other site
1008297001918	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
1008297001919	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297001920	active site
1008297001921	phosphorylation site [posttranslational modification]
1008297001922	intermolecular recognition site; other site
1008297001923	dimerization interface [polypeptide binding]; other site
1008297001924	Transcriptional regulator; Region: CitT; pfam12431
1008297001925	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1008297001926	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1008297001927	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1008297001928	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1008297001929	DNA-binding site [nucleotide binding]; DNA binding site
1008297001930	RNA-binding motif; other site
1008297001931	chromosome condensation membrane protein; Provisional; Region: PRK14196
1008297001932	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1008297001933	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1008297001934	putative active site [active]
1008297001935	catalytic triad [active]
1008297001936	putative dimer interface [polypeptide binding]; other site
1008297001937	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1008297001938	lipoyl synthase; Provisional; Region: PRK05481
1008297001939	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297001940	FeS/SAM binding site; other site
1008297001941	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1008297001942	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297001943	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1008297001944	substrate binding pocket [chemical binding]; other site
1008297001945	dimerization interface [polypeptide binding]; other site
1008297001946	lipoate-protein ligase B; Provisional; Region: PRK14342
1008297001947	hypothetical protein; Provisional; Region: PRK04998
1008297001948	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1008297001949	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1008297001950	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1008297001951	rare lipoprotein A; Provisional; Region: PRK10672
1008297001952	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1008297001953	Sporulation related domain; Region: SPOR; pfam05036
1008297001954	cell wall shape-determining protein; Provisional; Region: PRK10794
1008297001955	penicillin-binding protein 2; Provisional; Region: PRK10795
1008297001956	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1008297001957	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1008297001958	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1008297001959	ribosome-associated protein; Provisional; Region: PRK11538
1008297001960	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1008297001961	catalytic core [active]
1008297001962	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
1008297001963	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297001964	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297001965	homodimer interface [polypeptide binding]; other site
1008297001966	catalytic residue [active]
1008297001967	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1008297001968	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1008297001969	active site
1008297001970	(T/H)XGH motif; other site
1008297001971	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1008297001972	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1008297001973	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1008297001974	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1008297001975	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1008297001976	HIGH motif; other site
1008297001977	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1008297001978	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1008297001979	active site
1008297001980	KMSKS motif; other site
1008297001981	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1008297001982	tRNA binding surface [nucleotide binding]; other site
1008297001983	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1008297001984	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1008297001985	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
1008297001986	Propionate catabolism activator; Region: PrpR_N; pfam06506
1008297001987	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1008297001988	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297001989	Walker A motif; other site
1008297001990	ATP binding site [chemical binding]; other site
1008297001991	Walker B motif; other site
1008297001992	arginine finger; other site
1008297001993	hypothetical protein; Provisional; Region: PRK11032
1008297001994	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1008297001995	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1008297001996	Sel1-like repeats; Region: SEL1; smart00671
1008297001997	Sel1-like repeats; Region: SEL1; smart00671
1008297001998	Sel1-like repeats; Region: SEL1; smart00671
1008297001999	Sel1-like repeats; Region: SEL1; smart00671
1008297002000	Sel1-like repeats; Region: SEL1; smart00671
1008297002001	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1008297002002	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
1008297002003	HSP70 interaction site [polypeptide binding]; other site
1008297002004	putative hypothetical protein (pseudogene)
1008297002005	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
1008297002006	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
1008297002007	nucleotide binding site [chemical binding]; other site
1008297002008	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1008297002009	SBD interface [polypeptide binding]; other site
1008297002010	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1008297002011	active site
1008297002012	tetramer interface [polypeptide binding]; other site
1008297002013	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1008297002014	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1008297002015	Walker A/P-loop; other site
1008297002016	ATP binding site [chemical binding]; other site
1008297002017	Q-loop/lid; other site
1008297002018	ABC transporter signature motif; other site
1008297002019	Walker B; other site
1008297002020	D-loop; other site
1008297002021	H-loop/switch region; other site
1008297002022	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1008297002023	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297002024	dimer interface [polypeptide binding]; other site
1008297002025	conserved gate region; other site
1008297002026	putative PBP binding loops; other site
1008297002027	ABC-ATPase subunit interface; other site
1008297002028	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1008297002029	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297002030	dimer interface [polypeptide binding]; other site
1008297002031	conserved gate region; other site
1008297002032	putative PBP binding loops; other site
1008297002033	ABC-ATPase subunit interface; other site
1008297002034	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1008297002035	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297002036	substrate binding pocket [chemical binding]; other site
1008297002037	membrane-bound complex binding site; other site
1008297002038	hinge residues; other site
1008297002039	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1008297002040	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1008297002041	putative active site [active]
1008297002042	catalytic triad [active]
1008297002043	putative dimer interface [polypeptide binding]; other site
1008297002044	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1008297002045	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1008297002046	Transporter associated domain; Region: CorC_HlyC; smart01091
1008297002047	metal-binding heat shock protein; Provisional; Region: PRK00016
1008297002048	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1008297002049	PhoH-like protein; Region: PhoH; pfam02562
1008297002050	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1008297002051	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1008297002052	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297002053	FeS/SAM binding site; other site
1008297002054	TRAM domain; Region: TRAM; pfam01938
1008297002055	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1008297002056	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1008297002057	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1008297002058	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1008297002059	active site
1008297002060	dimer interface [polypeptide binding]; other site
1008297002061	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1008297002062	Ligand Binding Site [chemical binding]; other site
1008297002063	Molecular Tunnel; other site
1008297002064	UMP phosphatase; Provisional; Region: PRK10444
1008297002065	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297002066	active site
1008297002067	motif I; other site
1008297002068	motif II; other site
1008297002069	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297002070	MarR family; Region: MarR; pfam01047
1008297002071	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1008297002072	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1008297002073	nucleotide binding site [chemical binding]; other site
1008297002074	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1008297002075	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1008297002076	active site
1008297002077	dimer interface [polypeptide binding]; other site
1008297002078	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1008297002079	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1008297002080	active site
1008297002081	trimer interface [polypeptide binding]; other site
1008297002082	allosteric site; other site
1008297002083	active site lid [active]
1008297002084	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1008297002085	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1008297002086	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1008297002087	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1008297002088	active site turn [active]
1008297002089	phosphorylation site [posttranslational modification]
1008297002090	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1008297002091	HPr interaction site; other site
1008297002092	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1008297002093	active site
1008297002094	phosphorylation site [posttranslational modification]
1008297002095	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1008297002096	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1008297002097	active site
1008297002098	HIGH motif; other site
1008297002099	nucleotide binding site [chemical binding]; other site
1008297002100	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1008297002101	KMSKS motif; other site
1008297002102	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1008297002103	outer membrane porin, OprD family; Region: OprD; pfam03573
1008297002104	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1008297002105	YbfN-like lipoprotein; Region: YbfN; pfam13982
1008297002106	citrate-proton symporter; Provisional; Region: PRK15075
1008297002107	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297002108	putative substrate translocation pore; other site
1008297002109	tricarballylate utilization protein B; Provisional; Region: PRK15033
1008297002110	tricarballylate dehydrogenase; Validated; Region: PRK08274
1008297002111	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1008297002112	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297002113	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297002114	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1008297002115	putative dimerization interface [polypeptide binding]; other site
1008297002116	ferric uptake regulator; Provisional; Region: fur; PRK09462
1008297002117	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1008297002118	metal binding site 2 [ion binding]; metal-binding site
1008297002119	putative DNA binding helix; other site
1008297002120	metal binding site 1 [ion binding]; metal-binding site
1008297002121	dimer interface [polypeptide binding]; other site
1008297002122	structural Zn2+ binding site [ion binding]; other site
1008297002123	flavodoxin FldA; Validated; Region: PRK09267
1008297002124	LexA regulated protein; Provisional; Region: PRK11675
1008297002125	acyl-CoA esterase; Provisional; Region: PRK10673
1008297002126	PGAP1-like protein; Region: PGAP1; pfam07819
1008297002127	replication initiation regulator SeqA; Provisional; Region: PRK11187
1008297002128	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
1008297002129	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1008297002130	active site
1008297002131	substrate binding site [chemical binding]; other site
1008297002132	metal binding site [ion binding]; metal-binding site
1008297002133	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
1008297002134	putrescine transporter; Provisional; Region: potE; PRK10655
1008297002135	ornithine decarboxylase; Provisional; Region: PRK13578
1008297002136	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1008297002137	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1008297002138	homodimer interface [polypeptide binding]; other site
1008297002139	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297002140	catalytic residue [active]
1008297002141	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1008297002142	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1008297002143	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297002144	active site
1008297002145	phosphorylation site [posttranslational modification]
1008297002146	intermolecular recognition site; other site
1008297002147	dimerization interface [polypeptide binding]; other site
1008297002148	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297002149	DNA binding site [nucleotide binding]
1008297002150	sensor protein KdpD; Provisional; Region: PRK10490
1008297002151	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1008297002152	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1008297002153	Ligand Binding Site [chemical binding]; other site
1008297002154	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1008297002155	GAF domain; Region: GAF_3; pfam13492
1008297002156	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297002157	dimer interface [polypeptide binding]; other site
1008297002158	phosphorylation site [posttranslational modification]
1008297002159	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297002160	ATP binding site [chemical binding]; other site
1008297002161	Mg2+ binding site [ion binding]; other site
1008297002162	G-X-G motif; other site
1008297002163	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1008297002164	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1008297002165	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1008297002166	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1008297002167	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1008297002168	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1008297002169	DNA photolyase; Region: DNA_photolyase; pfam00875
1008297002170	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1008297002171	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297002172	putative substrate translocation pore; other site
1008297002173	POT family; Region: PTR2; pfam00854
1008297002174	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1008297002175	metal-binding protein; Provisional; Region: PRK10799
1008297002176	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1008297002177	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1008297002178	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1008297002179	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
1008297002180	putative active site [active]
1008297002181	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1008297002182	active site
1008297002183	DNA binding site [nucleotide binding]
1008297002184	Int/Topo IB signature motif; other site
1008297002185	putative udp-galactopyranose mutase (pseudogene)
1008297002186	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1008297002187	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1008297002188	active site
1008297002189	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1008297002190	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1008297002191	putative ADP-binding pocket [chemical binding]; other site
1008297002192	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1008297002193	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1008297002194	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1008297002195	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1008297002196	Walker A/P-loop; other site
1008297002197	ATP binding site [chemical binding]; other site
1008297002198	Q-loop/lid; other site
1008297002199	ABC transporter signature motif; other site
1008297002200	Walker B; other site
1008297002201	D-loop; other site
1008297002202	H-loop/switch region; other site
1008297002203	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1008297002204	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1008297002205	active site
1008297002206	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1008297002207	active site
1008297002208	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1008297002209	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
1008297002210	endonuclease VIII; Provisional; Region: PRK10445
1008297002211	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
1008297002212	DNA binding site [nucleotide binding]
1008297002213	catalytic residue [active]
1008297002214	putative catalytic residues [active]
1008297002215	H2TH interface [polypeptide binding]; other site
1008297002216	intercalation triad [nucleotide binding]; other site
1008297002217	substrate specificity determining residue; other site
1008297002218	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1008297002219	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1008297002220	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1008297002221	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1008297002222	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1008297002223	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1008297002224	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1008297002225	dimer interface [polypeptide binding]; other site
1008297002226	active site
1008297002227	citrylCoA binding site [chemical binding]; other site
1008297002228	NADH binding [chemical binding]; other site
1008297002229	cationic pore residues; other site
1008297002230	oxalacetate/citrate binding site [chemical binding]; other site
1008297002231	coenzyme A binding site [chemical binding]; other site
1008297002232	catalytic triad [active]
1008297002233	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1008297002234	proximal heme binding site [chemical binding]; other site
1008297002235	SdhD (CybS) interface [polypeptide binding]; other site
1008297002236	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1008297002237	SdhC subunit interface [polypeptide binding]; other site
1008297002238	proximal heme binding site [chemical binding]; other site
1008297002239	cardiolipin binding site; other site
1008297002240	Iron-sulfur protein interface; other site
1008297002241	proximal quinone binding site [chemical binding]; other site
1008297002242	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1008297002243	L-aspartate oxidase; Provisional; Region: PRK06175
1008297002244	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1008297002245	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1008297002246	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1008297002247	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1008297002248	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1008297002249	TPP-binding site [chemical binding]; other site
1008297002250	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1008297002251	dimer interface [polypeptide binding]; other site
1008297002252	PYR/PP interface [polypeptide binding]; other site
1008297002253	TPP binding site [chemical binding]; other site
1008297002254	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1008297002255	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1008297002256	E3 interaction surface; other site
1008297002257	lipoyl attachment site [posttranslational modification]; other site
1008297002258	e3 binding domain; Region: E3_binding; pfam02817
1008297002259	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1008297002260	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1008297002261	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1008297002262	CoA-ligase; Region: Ligase_CoA; pfam00549
1008297002263	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1008297002264	CoA binding domain; Region: CoA_binding; smart00881
1008297002265	CoA-ligase; Region: Ligase_CoA; pfam00549
1008297002266	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1008297002267	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1008297002268	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1008297002269	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1008297002270	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
1008297002271	hypothetical protein; Provisional; Region: PRK10588
1008297002272	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1008297002273	active site
1008297002274	colicin uptake protein TolQ; Provisional; Region: PRK10801
1008297002275	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1008297002276	colicin uptake protein TolR; Provisional; Region: PRK11024
1008297002277	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1008297002278	TolA C-terminal; Region: TolA; pfam06519
1008297002279	translocation protein TolB; Provisional; Region: tolB; PRK03629
1008297002280	TolB amino-terminal domain; Region: TolB_N; pfam04052
1008297002281	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1008297002282	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1008297002283	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1008297002284	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1008297002285	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1008297002286	ligand binding site [chemical binding]; other site
1008297002287	tol-pal system protein YbgF; Provisional; Region: PRK10803
1008297002288	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1008297002289	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1008297002290	quinolinate synthetase; Provisional; Region: PRK09375
1008297002291	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1008297002292	zinc transporter ZitB; Provisional; Region: PRK03557
1008297002293	YbgS-like protein; Region: YbgS; pfam13985
1008297002294	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1008297002295	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1008297002296	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain [Energy production and conversion]; Region: FumA; COG1838
1008297002297	fumarate hydratase; Provisional; Region: PRK06246
1008297002298	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297002299	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297002300	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1008297002301	dimerization interface [polypeptide binding]; other site
1008297002302	cell density-dependent motility repressor; Provisional; Region: PRK10082
1008297002303	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297002304	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1008297002305	dimerization interface [polypeptide binding]; other site
1008297002306	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1008297002307	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1008297002308	transmembrane helices; other site
1008297002309	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1008297002310	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1008297002311	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1008297002312	active site
1008297002313	catalytic residues [active]
1008297002314	metal binding site [ion binding]; metal-binding site
1008297002315	homodimer binding site [polypeptide binding]; other site
1008297002316	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1008297002317	carboxyltransferase (CT) interaction site; other site
1008297002318	biotinylation site [posttranslational modification]; other site
1008297002319	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1008297002320	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1008297002321	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1008297002322	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1008297002323	dimer interface [polypeptide binding]; other site
1008297002324	putative PBP binding regions; other site
1008297002325	ABC-ATPase subunit  interface; other site
1008297002326	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1008297002327	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1008297002328	Walker A/P-loop; other site
1008297002329	ATP binding site [chemical binding]; other site
1008297002330	Q-loop/lid; other site
1008297002331	ABC transporter signature motif; other site
1008297002332	Walker B; other site
1008297002333	D-loop; other site
1008297002334	H-loop/switch region; other site
1008297002335	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1008297002336	catalytic core [active]
1008297002337	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1008297002338	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1008297002339	active site
1008297002340	catalytic residues [active]
1008297002341	galactokinase; Provisional; Region: PRK05101
1008297002342	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1008297002343	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1008297002344	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1008297002345	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1008297002346	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1008297002347	dimer interface [polypeptide binding]; other site
1008297002348	active site
1008297002349	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1008297002350	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1008297002351	NAD binding site [chemical binding]; other site
1008297002352	homodimer interface [polypeptide binding]; other site
1008297002353	active site
1008297002354	substrate binding site [chemical binding]; other site
1008297002355	potential frameshift: common BLAST hit: gi|378988161|ref|YP_005251325.1| putative inner membrane protein
1008297002356	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1008297002357	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297002358	Walker A/P-loop; other site
1008297002359	ATP binding site [chemical binding]; other site
1008297002360	Q-loop/lid; other site
1008297002361	ABC transporter signature motif; other site
1008297002362	Walker B; other site
1008297002363	D-loop; other site
1008297002364	H-loop/switch region; other site
1008297002365	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297002366	Walker A/P-loop; other site
1008297002367	ATP binding site [chemical binding]; other site
1008297002368	Q-loop/lid; other site
1008297002369	ABC transporter signature motif; other site
1008297002370	Walker B; other site
1008297002371	D-loop; other site
1008297002372	H-loop/switch region; other site
1008297002373	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1008297002374	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1008297002375	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1008297002376	TOBE domain; Region: TOBE; pfam03459
1008297002377	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1008297002378	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1008297002379	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297002380	substrate binding pocket [chemical binding]; other site
1008297002381	membrane-bound complex binding site; other site
1008297002382	hinge residues; other site
1008297002383	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1008297002384	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297002385	dimer interface [polypeptide binding]; other site
1008297002386	conserved gate region; other site
1008297002387	putative PBP binding loops; other site
1008297002388	ABC-ATPase subunit interface; other site
1008297002389	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1008297002390	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297002391	Walker A/P-loop; other site
1008297002392	ATP binding site [chemical binding]; other site
1008297002393	Q-loop/lid; other site
1008297002394	ABC transporter signature motif; other site
1008297002395	Walker B; other site
1008297002396	D-loop; other site
1008297002397	H-loop/switch region; other site
1008297002398	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1008297002399	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1008297002400	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297002401	active site
1008297002402	motif I; other site
1008297002403	motif II; other site
1008297002404	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297002405	6-phosphogluconolactonase; Provisional; Region: PRK11028
1008297002406	acyl-CoA thioesterase; Provisional; Region: PRK10531
1008297002407	putative pectinesterase; Region: PLN02432; cl01911
1008297002408	imidazolonepropionase; Validated; Region: PRK09356
1008297002409	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1008297002410	active site
1008297002411	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
1008297002412	putative active site [active]
1008297002413	putative metal binding site [ion binding]; other site
1008297002414	histidine utilization repressor; Provisional; Region: PRK14999
1008297002415	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297002416	DNA-binding site [nucleotide binding]; DNA binding site
1008297002417	UTRA domain; Region: UTRA; pfam07702
1008297002418	urocanate hydratase; Provisional; Region: PRK05414
1008297002419	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1008297002420	active sites [active]
1008297002421	tetramer interface [polypeptide binding]; other site
1008297002422	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1008297002423	substrate binding site [chemical binding]; other site
1008297002424	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1008297002425	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1008297002426	inhibitor-cofactor binding pocket; inhibition site
1008297002427	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297002428	catalytic residue [active]
1008297002429	biotin synthase; Provisional; Region: PRK15108
1008297002430	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297002431	FeS/SAM binding site; other site
1008297002432	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1008297002433	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1008297002434	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1008297002435	substrate-cofactor binding pocket; other site
1008297002436	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297002437	catalytic residue [active]
1008297002438	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1008297002439	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297002440	S-adenosylmethionine binding site [chemical binding]; other site
1008297002441	AAA domain; Region: AAA_26; pfam13500
1008297002442	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1008297002443	excinuclease ABC subunit B; Provisional; Region: PRK05298
1008297002444	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1008297002445	ATP binding site [chemical binding]; other site
1008297002446	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297002447	nucleotide binding region [chemical binding]; other site
1008297002448	ATP-binding site [chemical binding]; other site
1008297002449	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1008297002450	UvrB/uvrC motif; Region: UVR; pfam02151
1008297002451	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
1008297002452	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
1008297002453	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
1008297002454	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1008297002455	Leucine-rich repeats; other site
1008297002456	Substrate binding site [chemical binding]; other site
1008297002457	Family of CofD-like proteins and proteins related to YvcK; Region: CofD_YvcK; cl00425
1008297002458	phosphate binding site [ion binding]; other site
1008297002459	Family of CofD-like proteins and proteins related to YvcK; Region: CofD_YvcK; cl00425
1008297002460	dimer interface [polypeptide binding]; other site
1008297002461	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1008297002462	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297002463	FeS/SAM binding site; other site
1008297002464	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1008297002465	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1008297002466	MPT binding site; other site
1008297002467	trimer interface [polypeptide binding]; other site
1008297002468	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1008297002469	trimer interface [polypeptide binding]; other site
1008297002470	dimer interface [polypeptide binding]; other site
1008297002471	putative active site [active]
1008297002472	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1008297002473	MoaE interaction surface [polypeptide binding]; other site
1008297002474	MoeB interaction surface [polypeptide binding]; other site
1008297002475	thiocarboxylated glycine; other site
1008297002476	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1008297002477	MoaE homodimer interface [polypeptide binding]; other site
1008297002478	MoaD interaction [polypeptide binding]; other site
1008297002479	active site residues [active]
1008297002480	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1008297002481	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1008297002482	BAX inhibitor (BI)-1/YccA-like protein family; Region: BI-1-like; cl00473
1008297002483	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1008297002484	Predicted integral membrane protein [Function unknown]; Region: COG0392
1008297002485	cardiolipin synthase 2; Provisional; Region: PRK11263
1008297002486	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1008297002487	putative active site [active]
1008297002488	catalytic site [active]
1008297002489	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1008297002490	putative active site [active]
1008297002491	catalytic site [active]
1008297002492	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1008297002493	putative catalytic site [active]
1008297002494	putative metal binding site [ion binding]; other site
1008297002495	putative phosphate binding site [ion binding]; other site
1008297002496	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1008297002497	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1008297002498	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1008297002499	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1008297002500	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1008297002501	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1008297002502	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1008297002503	Walker A/P-loop; other site
1008297002504	ATP binding site [chemical binding]; other site
1008297002505	Q-loop/lid; other site
1008297002506	ABC transporter signature motif; other site
1008297002507	Walker B; other site
1008297002508	D-loop; other site
1008297002509	H-loop/switch region; other site
1008297002510	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1008297002511	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1008297002512	Walker A/P-loop; other site
1008297002513	ATP binding site [chemical binding]; other site
1008297002514	Q-loop/lid; other site
1008297002515	ABC transporter signature motif; other site
1008297002516	Walker B; other site
1008297002517	D-loop; other site
1008297002518	H-loop/switch region; other site
1008297002519	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1008297002520	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1008297002521	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297002522	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1008297002523	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297002524	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1008297002525	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1008297002526	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1008297002527	ATP binding site [chemical binding]; other site
1008297002528	Mg++ binding site [ion binding]; other site
1008297002529	motif III; other site
1008297002530	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297002531	nucleotide binding region [chemical binding]; other site
1008297002532	ATP-binding site [chemical binding]; other site
1008297002533	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1008297002534	DEAD_2; Region: DEAD_2; pfam06733
1008297002535	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1008297002536	glycosyl transferase family protein; Provisional; Region: PRK08136
1008297002537	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1008297002538	hypothetical protein; Provisional; Region: PRK10259
1008297002539	hypothetical protein; Provisional; Region: PRK11019
1008297002540	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
1008297002541	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1008297002542	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1008297002543	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1008297002544	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1008297002545	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1008297002546	Walker A/P-loop; other site
1008297002547	ATP binding site [chemical binding]; other site
1008297002548	Q-loop/lid; other site
1008297002549	ABC transporter signature motif; other site
1008297002550	Walker B; other site
1008297002551	D-loop; other site
1008297002552	H-loop/switch region; other site
1008297002553	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1008297002554	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297002555	dimer interface [polypeptide binding]; other site
1008297002556	conserved gate region; other site
1008297002557	putative PBP binding loops; other site
1008297002558	ABC-ATPase subunit interface; other site
1008297002559	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1008297002560	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297002561	substrate binding pocket [chemical binding]; other site
1008297002562	membrane-bound complex binding site; other site
1008297002563	hinge residues; other site
1008297002564	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1008297002565	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1008297002566	dimerization interface [polypeptide binding]; other site
1008297002567	DPS ferroxidase diiron center [ion binding]; other site
1008297002568	ion pore; other site
1008297002569	threonine and homoserine efflux system; Provisional; Region: PRK10532
1008297002570	EamA-like transporter family; Region: EamA; pfam00892
1008297002571	outer membrane protein X; Provisional; Region: ompX; PRK09408
1008297002572	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1008297002573	Sulfatase; Region: Sulfatase; pfam00884
1008297002574	manganese transport regulator MntR; Provisional; Region: PRK11050
1008297002575	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1008297002576	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1008297002577	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1008297002578	transmembrane helices; other site
1008297002579	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1008297002580	L,D-transpeptidase; Provisional; Region: PRK10260
1008297002581	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1008297002582	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1008297002583	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1008297002584	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297002585	Walker A/P-loop; other site
1008297002586	ATP binding site [chemical binding]; other site
1008297002587	ABC transporter signature motif; other site
1008297002588	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1008297002589	Walker B; other site
1008297002590	ABC transporter; Region: ABC_tran_2; pfam12848
1008297002591	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1008297002592	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
1008297002593	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297002594	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1008297002595	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1008297002596	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297002597	active site
1008297002598	motif I; other site
1008297002599	motif II; other site
1008297002600	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297002601	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1008297002602	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1008297002603	dimer interface [polypeptide binding]; other site
1008297002604	active site
1008297002605	glycine loop; other site
1008297002606	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1008297002607	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297002608	FeS/SAM binding site; other site
1008297002609	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1008297002610	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1008297002611	ATP binding site [chemical binding]; other site
1008297002612	substrate interface [chemical binding]; other site
1008297002613	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1008297002614	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1008297002615	dimer interface [polypeptide binding]; other site
1008297002616	putative functional site; other site
1008297002617	putative MPT binding site; other site
1008297002618	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1008297002619	catalytic nucleophile [active]
1008297002620	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1008297002621	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297002622	Walker A/P-loop; other site
1008297002623	ATP binding site [chemical binding]; other site
1008297002624	Q-loop/lid; other site
1008297002625	ABC transporter signature motif; other site
1008297002626	Walker B; other site
1008297002627	D-loop; other site
1008297002628	H-loop/switch region; other site
1008297002629	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1008297002630	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297002631	Walker A/P-loop; other site
1008297002632	ATP binding site [chemical binding]; other site
1008297002633	Q-loop/lid; other site
1008297002634	ABC transporter signature motif; other site
1008297002635	Walker B; other site
1008297002636	D-loop; other site
1008297002637	H-loop/switch region; other site
1008297002638	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1008297002639	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1008297002640	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1008297002641	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1008297002642	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297002643	dimer interface [polypeptide binding]; other site
1008297002644	conserved gate region; other site
1008297002645	putative PBP binding loops; other site
1008297002646	ABC-ATPase subunit interface; other site
1008297002647	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1008297002648	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1008297002649	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297002650	dimer interface [polypeptide binding]; other site
1008297002651	conserved gate region; other site
1008297002652	putative PBP binding loops; other site
1008297002653	ABC-ATPase subunit interface; other site
1008297002654	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1008297002655	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1008297002656	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297002657	FeS/SAM binding site; other site
1008297002658	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1008297002659	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1008297002660	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1008297002661	Ligand binding site [chemical binding]; other site
1008297002662	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1008297002663	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1008297002664	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1008297002665	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1008297002666	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1008297002667	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1008297002668	active site
1008297002669	putative flavoprotein
1008297002670	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297002671	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297002672	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421
1008297002673	putative dimerization interface [polypeptide binding]; other site
1008297002674	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1008297002675	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1008297002676	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1008297002677	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1008297002678	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1008297002679	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1008297002680	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1008297002681	putative C-terminal domain interface [polypeptide binding]; other site
1008297002682	putative GSH binding site (G-site) [chemical binding]; other site
1008297002683	putative dimer interface [polypeptide binding]; other site
1008297002684	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1008297002685	putative N-terminal domain interface [polypeptide binding]; other site
1008297002686	putative dimer interface [polypeptide binding]; other site
1008297002687	putative substrate binding pocket (H-site) [chemical binding]; other site
1008297002688	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1008297002689	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1008297002690	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1008297002691	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1008297002692	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1008297002693	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297002694	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1008297002695	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1008297002696	active site
1008297002697	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1008297002698	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297002699	putative substrate translocation pore; other site
1008297002700	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1008297002701	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297002702	active site
1008297002703	motif I; other site
1008297002704	motif II; other site
1008297002705	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297002706	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297002707	putative substrate translocation pore; other site
1008297002708	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1008297002709	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
1008297002710	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297002711	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1008297002712	putative transporter; Provisional; Region: PRK04972
1008297002713	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1008297002714	TrkA-C domain; Region: TrkA_C; pfam02080
1008297002715	TrkA-C domain; Region: TrkA_C; pfam02080
1008297002716	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1008297002717	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1008297002718	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1008297002719	GSH binding site [chemical binding]; other site
1008297002720	catalytic residues [active]
1008297002721	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
1008297002722	oxygen-insensitive NADPH nitroreductase (pseudogene)
1008297002723	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1008297002724	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1008297002725	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1008297002726	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1008297002727	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1008297002728	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1008297002729	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297002730	Walker A/P-loop; other site
1008297002731	ATP binding site [chemical binding]; other site
1008297002732	Q-loop/lid; other site
1008297002733	ABC transporter signature motif; other site
1008297002734	Walker B; other site
1008297002735	D-loop; other site
1008297002736	H-loop/switch region; other site
1008297002737	TOBE domain; Region: TOBE_2; pfam08402
1008297002738	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1008297002739	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297002740	dimer interface [polypeptide binding]; other site
1008297002741	conserved gate region; other site
1008297002742	putative PBP binding loops; other site
1008297002743	ABC-ATPase subunit interface; other site
1008297002744	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1008297002745	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297002746	dimer interface [polypeptide binding]; other site
1008297002747	conserved gate region; other site
1008297002748	putative PBP binding loops; other site
1008297002749	ABC-ATPase subunit interface; other site
1008297002750	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1008297002751	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1008297002752	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297002753	S-adenosylmethionine binding site [chemical binding]; other site
1008297002754	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1008297002755	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1008297002756	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1008297002757	Sulfatase; Region: Sulfatase; cl17466
1008297002758	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1008297002759	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297002760	substrate binding pocket [chemical binding]; other site
1008297002761	membrane-bound complex binding site; other site
1008297002762	hinge residues; other site
1008297002763	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297002764	dimer interface [polypeptide binding]; other site
1008297002765	conserved gate region; other site
1008297002766	putative PBP binding loops; other site
1008297002767	ABC-ATPase subunit interface; other site
1008297002768	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1008297002769	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297002770	dimer interface [polypeptide binding]; other site
1008297002771	conserved gate region; other site
1008297002772	putative PBP binding loops; other site
1008297002773	ABC-ATPase subunit interface; other site
1008297002774	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1008297002775	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297002776	substrate binding pocket [chemical binding]; other site
1008297002777	membrane-bound complex binding site; other site
1008297002778	hinge residues; other site
1008297002779	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1008297002780	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297002781	Walker A/P-loop; other site
1008297002782	ATP binding site [chemical binding]; other site
1008297002783	Q-loop/lid; other site
1008297002784	ABC transporter signature motif; other site
1008297002785	Walker B; other site
1008297002786	D-loop; other site
1008297002787	H-loop/switch region; other site
1008297002788	putative lipoprotein; Provisional; Region: PRK10533
1008297002789	hypothetical protein; Provisional; Region: PRK02877
1008297002790	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1008297002791	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1008297002792	amidase catalytic site [active]
1008297002793	Zn binding residues [ion binding]; other site
1008297002794	substrate binding site [chemical binding]; other site
1008297002795	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1008297002796	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1008297002797	NAD(P) binding site [chemical binding]; other site
1008297002798	active site
1008297002799	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1008297002800	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1008297002801	putative NAD(P) binding site [chemical binding]; other site
1008297002802	putative active site [active]
1008297002803	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1008297002804	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1008297002805	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1008297002806	tetramer interface [polypeptide binding]; other site
1008297002807	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297002808	catalytic residue [active]
1008297002809	pyruvate dehydrogenase; Provisional; Region: PRK09124
1008297002810	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1008297002811	PYR/PP interface [polypeptide binding]; other site
1008297002812	dimer interface [polypeptide binding]; other site
1008297002813	tetramer interface [polypeptide binding]; other site
1008297002814	TPP binding site [chemical binding]; other site
1008297002815	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1008297002816	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1008297002817	TPP-binding site [chemical binding]; other site
1008297002818	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1008297002819	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1008297002820	FAD binding pocket [chemical binding]; other site
1008297002821	FAD binding motif [chemical binding]; other site
1008297002822	phosphate binding motif [ion binding]; other site
1008297002823	beta-alpha-beta structure motif; other site
1008297002824	NAD binding pocket [chemical binding]; other site
1008297002825	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1008297002826	catalytic loop [active]
1008297002827	iron binding site [ion binding]; other site
1008297002828	hybrid cluster protein; Provisional; Region: PRK05290
1008297002829	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1008297002830	ACS interaction site; other site
1008297002831	CODH interaction site; other site
1008297002832	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1008297002833	hybrid metal cluster; other site
1008297002834	Predicted membrane protein [Function unknown]; Region: COG2431
1008297002835	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1008297002836	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1008297002837	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1008297002838	putative active site [active]
1008297002839	putative metal-binding site [ion binding]; other site
1008297002840	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
1008297002841	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1008297002842	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1008297002843	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297002844	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1008297002845	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1008297002846	Walker A/P-loop; other site
1008297002847	ATP binding site [chemical binding]; other site
1008297002848	Q-loop/lid; other site
1008297002849	ABC transporter signature motif; other site
1008297002850	Walker B; other site
1008297002851	D-loop; other site
1008297002852	H-loop/switch region; other site
1008297002853	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1008297002854	FtsX-like permease family; Region: FtsX; pfam02687
1008297002855	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1008297002856	DNA-binding site [nucleotide binding]; DNA binding site
1008297002857	RNA-binding motif; other site
1008297002858	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1008297002859	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1008297002860	Clp amino terminal domain; Region: Clp_N; pfam02861
1008297002861	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297002862	Walker A motif; other site
1008297002863	ATP binding site [chemical binding]; other site
1008297002864	Walker B motif; other site
1008297002865	arginine finger; other site
1008297002866	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297002867	Walker A motif; other site
1008297002868	ATP binding site [chemical binding]; other site
1008297002869	Walker B motif; other site
1008297002870	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1008297002871	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1008297002872	Integrase core domain; Region: rve; pfam00665
1008297002873	Integrase core domain; Region: rve_3; pfam13683
1008297002874	Helix-turn-helix domain; Region: HTH_28; pfam13518
1008297002875	Isochorismatase family; Region: Isochorismatase; pfam00857
1008297002876	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1008297002877	catalytic triad [active]
1008297002878	dimer interface [polypeptide binding]; other site
1008297002879	conserved cis-peptide bond; other site
1008297002880	Pirin-related protein [General function prediction only]; Region: COG1741
1008297002881	Pirin; Region: Pirin; pfam02678
1008297002882	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1008297002883	LysR family transcriptional regulator; Provisional; Region: PRK14997
1008297002884	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297002885	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
1008297002886	putative effector binding pocket; other site
1008297002887	putative dimerization interface [polypeptide binding]; other site
1008297002888	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1008297002889	rRNA binding site [nucleotide binding]; other site
1008297002890	predicted 30S ribosome binding site; other site
1008297002891	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1008297002892	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1008297002893	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1008297002894	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297002895	Walker A/P-loop; other site
1008297002896	ATP binding site [chemical binding]; other site
1008297002897	Q-loop/lid; other site
1008297002898	ABC transporter signature motif; other site
1008297002899	Walker B; other site
1008297002900	D-loop; other site
1008297002901	H-loop/switch region; other site
1008297002902	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1008297002903	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1008297002904	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297002905	Walker A/P-loop; other site
1008297002906	ATP binding site [chemical binding]; other site
1008297002907	Q-loop/lid; other site
1008297002908	ABC transporter signature motif; other site
1008297002909	Walker B; other site
1008297002910	D-loop; other site
1008297002911	H-loop/switch region; other site
1008297002912	thioredoxin reductase; Provisional; Region: PRK10262
1008297002913	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1008297002914	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297002915	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1008297002916	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1008297002917	putative DNA binding site [nucleotide binding]; other site
1008297002918	putative Zn2+ binding site [ion binding]; other site
1008297002919	AsnC family; Region: AsnC_trans_reg; pfam01037
1008297002920	DNA translocase FtsK; Provisional; Region: PRK10263
1008297002921	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1008297002922	DNA translocase FtsK; Provisional; Region: PRK10263
1008297002923	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1008297002924	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1008297002925	periplasmic chaperone LolA; Region: lolA; TIGR00547
1008297002926	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1008297002927	recombination factor protein RarA; Reviewed; Region: PRK13342
1008297002928	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297002929	Walker A motif; other site
1008297002930	ATP binding site [chemical binding]; other site
1008297002931	Walker B motif; other site
1008297002932	arginine finger; other site
1008297002933	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1008297002934	seryl-tRNA synthetase; Provisional; Region: PRK05431
1008297002935	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1008297002936	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1008297002937	dimer interface [polypeptide binding]; other site
1008297002938	active site
1008297002939	motif 1; other site
1008297002940	motif 2; other site
1008297002941	motif 3; other site
1008297002942	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1008297002943	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1008297002944	putative [Fe4-S4] binding site [ion binding]; other site
1008297002945	putative molybdopterin cofactor binding site [chemical binding]; other site
1008297002946	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1008297002947	putative molybdopterin cofactor binding site; other site
1008297002948	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1008297002949	4Fe-4S binding domain; Region: Fer4; pfam00037
1008297002950	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1008297002951	putative MFS family transporter protein; Provisional; Region: PRK03633
1008297002952	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297002953	putative substrate translocation pore; other site
1008297002954	inner membrane transporter YjeM; Provisional; Region: PRK15238
1008297002955	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1008297002956	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297002957	FeS/SAM binding site; other site
1008297002958	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
1008297002959	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1008297002960	Pyruvate formate lyase 1; Region: PFL1; cd01678
1008297002961	coenzyme A binding site [chemical binding]; other site
1008297002962	active site
1008297002963	catalytic residues [active]
1008297002964	glycine loop; other site
1008297002965	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1008297002966	uncharacterized domain; Region: TIGR00702
1008297002967	YcaO-like family; Region: YcaO; pfam02624
1008297002968	Predicted membrane protein [Function unknown]; Region: COG2323
1008297002969	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1008297002970	homodimer interface [polypeptide binding]; other site
1008297002971	substrate-cofactor binding pocket; other site
1008297002972	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297002973	catalytic residue [active]
1008297002974	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1008297002975	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
1008297002976	hinge; other site
1008297002977	active site
1008297002978	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1008297002979	cytidylate kinase; Provisional; Region: cmk; PRK00023
1008297002980	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1008297002981	CMP-binding site; other site
1008297002982	The sites determining sugar specificity; other site
1008297002983	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1008297002984	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1008297002985	RNA binding site [nucleotide binding]; other site
1008297002986	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1008297002987	RNA binding site [nucleotide binding]; other site
1008297002988	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1008297002989	RNA binding site [nucleotide binding]; other site
1008297002990	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1008297002991	RNA binding site [nucleotide binding]; other site
1008297002992	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1008297002993	RNA binding site [nucleotide binding]; other site
1008297002994	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1008297002995	IHF dimer interface [polypeptide binding]; other site
1008297002996	IHF - DNA interface [nucleotide binding]; other site
1008297002997	ComEC family competence protein; Provisional; Region: PRK11539
1008297002998	Competence protein; Region: Competence; pfam03772
1008297002999	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1008297003000	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1008297003001	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1008297003002	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1008297003003	Walker A/P-loop; other site
1008297003004	ATP binding site [chemical binding]; other site
1008297003005	Q-loop/lid; other site
1008297003006	ABC transporter signature motif; other site
1008297003007	Walker B; other site
1008297003008	D-loop; other site
1008297003009	H-loop/switch region; other site
1008297003010	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1008297003011	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1008297003012	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
1008297003013	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1008297003014	hypothetical protein; Provisional; Region: PRK11827
1008297003015	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1008297003016	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1008297003017	Ligand binding site; other site
1008297003018	oligomer interface; other site
1008297003019	hypothetical protein; Provisional; Region: PRK10593
1008297003020	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1008297003021	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1008297003022	putative active site [active]
1008297003023	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1008297003024	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297003025	S-adenosylmethionine binding site [chemical binding]; other site
1008297003026	condesin subunit F; Provisional; Region: PRK05260
1008297003027	condesin subunit E; Provisional; Region: PRK05256
1008297003028	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
1008297003029	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1008297003030	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1008297003031	murein L,D-transpeptidase; Provisional; Region: PRK10594
1008297003032	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1008297003033	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1008297003034	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1008297003035	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1008297003036	Peptidase M15; Region: Peptidase_M15_3; cl01194
1008297003037	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1008297003038	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1008297003039	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297003040	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297003041	homodimer interface [polypeptide binding]; other site
1008297003042	catalytic residue [active]
1008297003043	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1008297003044	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1008297003045	trimer interface [polypeptide binding]; other site
1008297003046	eyelet of channel; other site
1008297003047	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1008297003048	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1008297003049	putative anticodon binding site; other site
1008297003050	putative dimer interface [polypeptide binding]; other site
1008297003051	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1008297003052	homodimer interface [polypeptide binding]; other site
1008297003053	motif 1; other site
1008297003054	motif 2; other site
1008297003055	active site
1008297003056	motif 3; other site
1008297003057	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1008297003058	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1008297003059	putative DNA binding site [nucleotide binding]; other site
1008297003060	putative Zn2+ binding site [ion binding]; other site
1008297003061	AsnC family; Region: AsnC_trans_reg; pfam01037
1008297003062	diaminopropionate ammonia lyase
1008297003063	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1008297003064	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1008297003065	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1008297003066	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1008297003067	active site
1008297003068	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1008297003069	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1008297003070	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
1008297003071	Int/Topo IB signature motif; other site
1008297003072	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1008297003073	RecT family; Region: RecT; pfam03837
1008297003074	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1008297003075	exonuclease VIII; Reviewed; Region: PRK09709
1008297003076	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
1008297003077	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1008297003078	primosomal protein DnaI; Provisional; Region: PRK02854
1008297003079	putative replication protein; Provisional; Region: PRK12377
1008297003080	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297003081	Walker A motif; other site
1008297003082	ATP binding site [chemical binding]; other site
1008297003083	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1008297003084	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1008297003085	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1008297003086	DinI-like family; Region: DinI; pfam06183
1008297003087	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1008297003088	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1008297003089	Antitermination protein; Region: Antiterm; pfam03589
1008297003090	Antitermination protein; Region: Antiterm; pfam03589
1008297003091	PipA protein; Region: PipA; pfam07108
1008297003092	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1008297003093	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1008297003094	catalytic residues [active]
1008297003095	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1008297003096	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1008297003097	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1008297003098	Domain of unknown function (DUF1859); Region: DUF1859; pfam08948
1008297003099	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1008297003100	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1008297003101	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1008297003102	active site residues [active]
1008297003103	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
1008297003104	Uncharacterized conserved protein [Function unknown]; Region: COG5471
1008297003105	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
1008297003106	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1008297003107	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1008297003108	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1008297003109	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
1008297003110	Minor tail protein T; Region: Phage_tail_T; cl05636
1008297003111	Phage-related minor tail protein [Function unknown]; Region: COG5281
1008297003112	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1008297003113	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1008297003114	Phage-related protein [Function unknown]; Region: COG4718
1008297003115	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1008297003116	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cl00891
1008297003117	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1008297003118	active site
1008297003119	Cu2+ binding site [ion binding]; other site
1008297003120	Zn2+ binding site [ion binding]; other site
1008297003121	P-class dimer interface [polypeptide binding]; other site
1008297003122	Phage-related protein [Function unknown]; Region: gp18; COG4672
1008297003123	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1008297003124	MPN+ (JAMM) motif; other site
1008297003125	Zinc-binding site [ion binding]; other site
1008297003126	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1008297003127	NlpC/P60 family; Region: NLPC_P60; cl17555
1008297003128	Phage-related protein, tail component [Function unknown]; Region: COG4723
1008297003129	Phage-related protein, tail component [Function unknown]; Region: COG4733
1008297003130	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1008297003131	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1008297003132	Interdomain contacts; other site
1008297003133	Cytokine receptor motif; other site
1008297003134	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1008297003135	Fibronectin type III protein; Region: DUF3672; pfam12421
1008297003136	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1008297003137	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1008297003138	Phage Tail Collar Domain; Region: Collar; pfam07484
1008297003139	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1008297003140	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
1008297003141	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1008297003142	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1008297003143	hypothetical protein; Provisional; Region: PRK09951
1008297003144	DinI-like family; Region: DinI; cl11630
1008297003145	aminopeptidase N; Provisional; Region: pepN; PRK14015
1008297003146	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1008297003147	active site
1008297003148	Zn binding site [ion binding]; other site
1008297003149	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1008297003150	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1008297003151	quinone interaction residues [chemical binding]; other site
1008297003152	active site
1008297003153	catalytic residues [active]
1008297003154	FMN binding site [chemical binding]; other site
1008297003155	substrate binding site [chemical binding]; other site
1008297003156	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1008297003157	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1008297003158	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1008297003159	MOSC domain; Region: MOSC; pfam03473
1008297003160	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1008297003161	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1008297003162	catalytic loop [active]
1008297003163	iron binding site [ion binding]; other site
1008297003164	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1008297003165	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1008297003166	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1008297003167	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297003168	S-adenosylmethionine binding site [chemical binding]; other site
1008297003169	ABC transporter ATPase component; Reviewed; Region: PRK11147
1008297003170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297003171	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297003172	Walker A/P-loop; other site
1008297003173	Walker A/P-loop; other site
1008297003174	ATP binding site [chemical binding]; other site
1008297003175	ATP binding site [chemical binding]; other site
1008297003176	Q-loop/lid; other site
1008297003177	Q-loop/lid; other site
1008297003178	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1008297003179	ABC transporter signature motif; other site
1008297003180	Walker B; other site
1008297003181	D-loop; other site
1008297003182	ABC transporter; Region: ABC_tran_2; pfam12848
1008297003183	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1008297003184	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1008297003185	Paraquat-inducible protein A; Region: PqiA; pfam04403
1008297003186	Paraquat-inducible protein A; Region: PqiA; pfam04403
1008297003187	putative secreted protein
1008297003188	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1008297003189	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1008297003190	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1008297003191	active site 1 [active]
1008297003192	dimer interface [polypeptide binding]; other site
1008297003193	active site 2 [active]
1008297003194	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1008297003195	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1008297003196	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1008297003197	outer membrane protein A; Reviewed; Region: PRK10808
1008297003198	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1008297003199	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1008297003200	ligand binding site [chemical binding]; other site
1008297003201	cell division inhibitor SulA; Region: sula; TIGR00623
1008297003202	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
1008297003203	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1008297003204	TIGR01666 family membrane protein; Region: YCCS
1008297003205	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1008297003206	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1008297003207	Predicted membrane protein [Function unknown]; Region: COG3304
1008297003208	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1008297003209	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1008297003210	DNA helicase IV; Provisional; Region: helD; PRK11054
1008297003211	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1008297003212	Part of AAA domain; Region: AAA_19; pfam13245
1008297003213	Family description; Region: UvrD_C_2; pfam13538
1008297003214	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1008297003215	active site
1008297003216	dimer interfaces [polypeptide binding]; other site
1008297003217	catalytic residues [active]
1008297003218	hypothetical protein; Provisional; Region: PRK03641
1008297003219	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
1008297003220	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1008297003221	heat shock protein HspQ; Provisional; Region: PRK14129
1008297003222	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1008297003223	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1008297003224	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1008297003225	putative RNA binding site [nucleotide binding]; other site
1008297003226	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297003227	S-adenosylmethionine binding site [chemical binding]; other site
1008297003228	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1008297003229	substrate binding site [chemical binding]; other site
1008297003230	Cupin domain; Region: Cupin_2; cl17218
1008297003231	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1008297003232	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297003233	acylphosphatase; Provisional; Region: PRK14426
1008297003234	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1008297003235	sulfur transfer protein TusE; Provisional; Region: PRK11508
1008297003236	YccA-like proteins; Region: YccA_like; cd10433
1008297003237	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1008297003238	PipA protein; Region: PipA; pfam07108
1008297003239	secreted effector protein PipB; Provisional; Region: PRK15197
1008297003240	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1008297003241	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1008297003242	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1008297003243	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
1008297003244	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
1008297003245	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
1008297003246	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
1008297003247	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1008297003248	HAMP domain; Region: HAMP; pfam00672
1008297003249	dimerization interface [polypeptide binding]; other site
1008297003250	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297003251	dimer interface [polypeptide binding]; other site
1008297003252	phosphorylation site [posttranslational modification]
1008297003253	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297003254	ATP binding site [chemical binding]; other site
1008297003255	Mg2+ binding site [ion binding]; other site
1008297003256	G-X-G motif; other site
1008297003257	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
1008297003258	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297003259	active site
1008297003260	phosphorylation site [posttranslational modification]
1008297003261	intermolecular recognition site; other site
1008297003262	dimerization interface [polypeptide binding]; other site
1008297003263	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297003264	DNA binding site [nucleotide binding]
1008297003265	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1008297003266	active site
1008297003267	homotetramer interface [polypeptide binding]; other site
1008297003268	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
1008297003269	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
1008297003270	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1008297003271	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1008297003272	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1008297003273	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
1008297003274	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1008297003275	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1008297003276	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
1008297003277	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
1008297003278	NAD binding site [chemical binding]; other site
1008297003279	catalytic residues [active]
1008297003280	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
1008297003281	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1008297003282	putative active site [active]
1008297003283	putative metal binding site [ion binding]; other site
1008297003284	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
1008297003285	putative substrate binding pocket [chemical binding]; other site
1008297003286	trimer interface [polypeptide binding]; other site
1008297003287	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
1008297003288	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1008297003289	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297003290	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1008297003291	putative substrate translocation pore; other site
1008297003292	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
1008297003293	Cupin domain; Region: Cupin_2; pfam07883
1008297003294	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297003295	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
1008297003296	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
1008297003297	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
1008297003298	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
1008297003299	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1008297003300	HSP70 interaction site [polypeptide binding]; other site
1008297003301	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1008297003302	substrate binding site [polypeptide binding]; other site
1008297003303	dimer interface [polypeptide binding]; other site
1008297003304	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
1008297003305	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1008297003306	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1008297003307	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1008297003308	DsbD alpha interface [polypeptide binding]; other site
1008297003309	catalytic residues [active]
1008297003310	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
1008297003311	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1008297003312	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1008297003313	catalytic residues [active]
1008297003314	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1008297003315	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1008297003316	catalytic residues [active]
1008297003317	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1008297003318	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1008297003319	catalytic core [active]
1008297003320	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1008297003321	hypothetical protein; Provisional; Region: PRK10174
1008297003322	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1008297003323	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1008297003324	General stress protein [General function prediction only]; Region: GsiB; COG3729
1008297003325	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1008297003326	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297003327	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1008297003328	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1008297003329	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1008297003330	Predicted transcriptional regulator [Transcription]; Region: COG3905
1008297003331	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1008297003332	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1008297003333	Glutamate binding site [chemical binding]; other site
1008297003334	NAD binding site [chemical binding]; other site
1008297003335	catalytic residues [active]
1008297003336	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1008297003337	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1008297003338	Na binding site [ion binding]; other site
1008297003339	hypothetical protein; Provisional; Region: PRK10536
1008297003340	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1008297003341	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1008297003342	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1008297003343	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1008297003344	putative active site [active]
1008297003345	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
1008297003346	Na binding site [ion binding]; other site
1008297003347	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
1008297003348	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1008297003349	putative active site cavity [active]
1008297003350	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
1008297003351	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
1008297003352	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1008297003353	putative sialic acid transporter; Provisional; Region: PRK12307
1008297003354	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297003355	putative substrate translocation pore; other site
1008297003356	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1008297003357	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1008297003358	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1008297003359	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1008297003360	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1008297003361	putative ligand binding site [chemical binding]; other site
1008297003362	NAD binding site [chemical binding]; other site
1008297003363	dimerization interface [polypeptide binding]; other site
1008297003364	catalytic site [active]
1008297003365	putative hydrolase; Validated; Region: PRK09248
1008297003366	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1008297003367	active site
1008297003368	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1008297003369	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1008297003370	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
1008297003371	curli assembly protein CsgF; Provisional; Region: PRK10050
1008297003372	curli assembly protein CsgE; Provisional; Region: PRK10386
1008297003373	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1008297003374	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297003375	DNA binding residues [nucleotide binding]
1008297003376	dimerization interface [polypeptide binding]; other site
1008297003377	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1008297003378	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1008297003379	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1008297003380	major curlin subunit; Provisional; Region: csgA; PRK10051
1008297003381	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1008297003382	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
1008297003383	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1008297003384	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1008297003385	putative ADP-ribose binding site [chemical binding]; other site
1008297003386	putative active site [active]
1008297003387	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1008297003388	PLD-like domain; Region: PLDc_2; pfam13091
1008297003389	putative active site [active]
1008297003390	catalytic site [active]
1008297003391	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1008297003392	PLD-like domain; Region: PLDc_2; pfam13091
1008297003393	putative active site [active]
1008297003394	catalytic site [active]
1008297003395	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1008297003396	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1008297003397	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1008297003398	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
1008297003399	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1008297003400	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1008297003401	Ligand binding site; other site
1008297003402	DXD motif; other site
1008297003403	lipoprotein; Provisional; Region: PRK10175
1008297003404	secY/secA suppressor protein; Provisional; Region: PRK11467
1008297003405	drug efflux system protein MdtG; Provisional; Region: PRK09874
1008297003406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297003407	putative substrate translocation pore; other site
1008297003408	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1008297003409	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1008297003410	putative acyl-acceptor binding pocket; other site
1008297003411	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1008297003412	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1008297003413	active site residue [active]
1008297003414	hypothetical protein; Provisional; Region: PRK03757
1008297003415	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1008297003416	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
1008297003417	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1008297003418	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1008297003419	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1008297003420	DNA damage-inducible protein I; Provisional; Region: PRK10597
1008297003421	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1008297003422	active site
1008297003423	substrate binding pocket [chemical binding]; other site
1008297003424	dimer interface [polypeptide binding]; other site
1008297003425	lipoprotein; Provisional; Region: PRK10598
1008297003426	glutaredoxin 2; Provisional; Region: PRK10387
1008297003427	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1008297003428	C-terminal domain interface [polypeptide binding]; other site
1008297003429	GSH binding site (G-site) [chemical binding]; other site
1008297003430	catalytic residues [active]
1008297003431	putative dimer interface [polypeptide binding]; other site
1008297003432	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1008297003433	N-terminal domain interface [polypeptide binding]; other site
1008297003434	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1008297003435	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297003436	putative substrate translocation pore; other site
1008297003437	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1008297003438	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1008297003439	hypothetical protein; Provisional; Region: PRK11239
1008297003440	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1008297003441	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1008297003442	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1008297003443	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1008297003444	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1008297003445	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1008297003446	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
1008297003447	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
1008297003448	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
1008297003449	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1008297003450	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1008297003451	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1008297003452	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1008297003453	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1008297003454	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1008297003455	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1008297003456	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
1008297003457	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1008297003458	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1008297003459	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1008297003460	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1008297003461	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1008297003462	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1008297003463	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1008297003464	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1008297003465	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1008297003466	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1008297003467	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1008297003468	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1008297003469	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1008297003470	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1008297003471	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1008297003472	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1008297003473	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1008297003474	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1008297003475	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1008297003476	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1008297003477	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1008297003478	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1008297003479	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1008297003480	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1008297003481	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1008297003482	homodimer interface [polypeptide binding]; other site
1008297003483	oligonucleotide binding site [chemical binding]; other site
1008297003484	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1008297003485	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1008297003486	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1008297003487	RNA binding surface [nucleotide binding]; other site
1008297003488	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1008297003489	active site
1008297003490	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1008297003491	Maf-like protein; Region: Maf; pfam02545
1008297003492	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1008297003493	active site
1008297003494	dimer interface [polypeptide binding]; other site
1008297003495	hypothetical protein; Provisional; Region: PRK11193
1008297003496	putative phosphate acyltransferase; Provisional; Region: PRK05331
1008297003497	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1008297003498	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1008297003499	dimer interface [polypeptide binding]; other site
1008297003500	active site
1008297003501	CoA binding pocket [chemical binding]; other site
1008297003502	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1008297003503	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1008297003504	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1008297003505	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1008297003506	NAD(P) binding site [chemical binding]; other site
1008297003507	homotetramer interface [polypeptide binding]; other site
1008297003508	homodimer interface [polypeptide binding]; other site
1008297003509	active site
1008297003510	acyl carrier protein; Provisional; Region: acpP; PRK00982
1008297003511	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1008297003512	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1008297003513	dimer interface [polypeptide binding]; other site
1008297003514	active site
1008297003515	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1008297003516	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1008297003517	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297003518	catalytic residue [active]
1008297003519	conserved hypothetical protein, YceG family; Region: TIGR00247
1008297003520	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1008297003521	dimerization interface [polypeptide binding]; other site
1008297003522	thymidylate kinase; Validated; Region: tmk; PRK00698
1008297003523	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1008297003524	TMP-binding site; other site
1008297003525	ATP-binding site [chemical binding]; other site
1008297003526	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1008297003527	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1008297003528	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1008297003529	active site
1008297003530	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1008297003531	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1008297003532	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1008297003533	active site turn [active]
1008297003534	phosphorylation site [posttranslational modification]
1008297003535	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1008297003536	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1008297003537	N-terminal plug; other site
1008297003538	ligand-binding site [chemical binding]; other site
1008297003539	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1008297003540	nucleotide binding site/active site [active]
1008297003541	HIT family signature motif; other site
1008297003542	catalytic residue [active]
1008297003543	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1008297003544	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1008297003545	putative dimer interface [polypeptide binding]; other site
1008297003546	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1008297003547	thiamine kinase; Region: ycfN_thiK; TIGR02721
1008297003548	thiamine kinase; Provisional; Region: thiK; PRK10271
1008297003549	substrate binding site [chemical binding]; other site
1008297003550	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1008297003551	beta-hexosaminidase; Provisional; Region: PRK05337
1008297003552	hypothetical protein; Provisional; Region: PRK04940
1008297003553	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1008297003554	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297003555	hypothetical protein; Provisional; Region: PRK11280
1008297003556	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1008297003557	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297003558	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1008297003559	L,D-transpeptidase; Provisional; Region: PRK10190
1008297003560	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1008297003561	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1008297003562	transcription-repair coupling factor; Provisional; Region: PRK10689
1008297003563	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1008297003564	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1008297003565	ATP binding site [chemical binding]; other site
1008297003566	putative Mg++ binding site [ion binding]; other site
1008297003567	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297003568	nucleotide binding region [chemical binding]; other site
1008297003569	ATP-binding site [chemical binding]; other site
1008297003570	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1008297003571	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1008297003572	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1008297003573	FtsX-like permease family; Region: FtsX; pfam02687
1008297003574	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1008297003575	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1008297003576	Walker A/P-loop; other site
1008297003577	ATP binding site [chemical binding]; other site
1008297003578	Q-loop/lid; other site
1008297003579	ABC transporter signature motif; other site
1008297003580	Walker B; other site
1008297003581	D-loop; other site
1008297003582	H-loop/switch region; other site
1008297003583	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1008297003584	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1008297003585	FtsX-like permease family; Region: FtsX; pfam02687
1008297003586	fructokinase; Reviewed; Region: PRK09557
1008297003587	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1008297003588	nucleotide binding site [chemical binding]; other site
1008297003589	NAD-dependent deacetylase; Provisional; Region: PRK00481
1008297003590	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1008297003591	NAD+ binding site [chemical binding]; other site
1008297003592	substrate binding site [chemical binding]; other site
1008297003593	Zn binding site [ion binding]; other site
1008297003594	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1008297003595	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1008297003596	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1008297003597	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297003598	dimer interface [polypeptide binding]; other site
1008297003599	conserved gate region; other site
1008297003600	putative PBP binding loops; other site
1008297003601	ABC-ATPase subunit interface; other site
1008297003602	Sif protein; Region: Sif; pfam06767
1008297003603	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1008297003604	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297003605	dimer interface [polypeptide binding]; other site
1008297003606	conserved gate region; other site
1008297003607	putative PBP binding loops; other site
1008297003608	ABC-ATPase subunit interface; other site
1008297003609	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1008297003610	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297003611	Walker A/P-loop; other site
1008297003612	ATP binding site [chemical binding]; other site
1008297003613	Q-loop/lid; other site
1008297003614	ABC transporter signature motif; other site
1008297003615	Walker B; other site
1008297003616	D-loop; other site
1008297003617	H-loop/switch region; other site
1008297003618	TOBE domain; Region: TOBE_2; pfam08402
1008297003619	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1008297003620	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1008297003621	metal binding site [ion binding]; metal-binding site
1008297003622	dimer interface [polypeptide binding]; other site
1008297003623	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1008297003624	hypothetical protein (pseudogene)
1008297003625	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1008297003626	Cupin-like domain; Region: Cupin_8; pfam13621
1008297003627	sensor protein PhoQ; Provisional; Region: PRK10815
1008297003628	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1008297003629	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1008297003630	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297003631	ATP binding site [chemical binding]; other site
1008297003632	Mg2+ binding site [ion binding]; other site
1008297003633	G-X-G motif; other site
1008297003634	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1008297003635	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297003636	active site
1008297003637	phosphorylation site [posttranslational modification]
1008297003638	intermolecular recognition site; other site
1008297003639	dimerization interface [polypeptide binding]; other site
1008297003640	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297003641	DNA binding site [nucleotide binding]
1008297003642	adenylosuccinate lyase; Provisional; Region: PRK09285
1008297003643	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1008297003644	tetramer interface [polypeptide binding]; other site
1008297003645	active site
1008297003646	putative lysogenization regulator; Reviewed; Region: PRK00218
1008297003647	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1008297003648	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1008297003649	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1008297003650	nudix motif; other site
1008297003651	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
1008297003652	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1008297003653	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1008297003654	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1008297003655	probable active site [active]
1008297003656	isocitrate dehydrogenase; Validated; Region: PRK07362
1008297003657	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1008297003658	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
1008297003659	DinI-like family; Region: DinI; pfam06183
1008297003660	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1008297003661	lysozyme inhibitor; Provisional; Region: PRK13791
1008297003662	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1008297003663	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1008297003664	putative dimer interface [polypeptide binding]; other site
1008297003665	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
1008297003666	BNR repeat-like domain; Region: BNR_2; pfam13088
1008297003667	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1008297003668	TRL-like protein family; Region: TRL; pfam13146
1008297003669	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
1008297003670	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1008297003671	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1008297003672	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297003673	dimer interface [polypeptide binding]; other site
1008297003674	conserved gate region; other site
1008297003675	ABC-ATPase subunit interface; other site
1008297003676	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1008297003677	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297003678	dimer interface [polypeptide binding]; other site
1008297003679	conserved gate region; other site
1008297003680	putative PBP binding loops; other site
1008297003681	ABC-ATPase subunit interface; other site
1008297003682	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297003683	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
1008297003684	Walker A/P-loop; other site
1008297003685	ATP binding site [chemical binding]; other site
1008297003686	Q-loop/lid; other site
1008297003687	ABC transporter signature motif; other site
1008297003688	Walker B; other site
1008297003689	D-loop; other site
1008297003690	H-loop/switch region; other site
1008297003691	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297003692	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1008297003693	Walker A/P-loop; other site
1008297003694	ATP binding site [chemical binding]; other site
1008297003695	Q-loop/lid; other site
1008297003696	ABC transporter signature motif; other site
1008297003697	Walker B; other site
1008297003698	D-loop; other site
1008297003699	H-loop/switch region; other site
1008297003700	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1008297003701	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1008297003702	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
1008297003703	dimerization interface [polypeptide binding]; other site
1008297003704	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1008297003705	aminoglycoside resistance protein; Provisional; Region: PRK13746
1008297003706	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1008297003707	active site
1008297003708	NTP binding site [chemical binding]; other site
1008297003709	metal binding triad [ion binding]; metal-binding site
1008297003710	antibiotic binding site [chemical binding]; other site
1008297003711	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1008297003712	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297003713	DNA binding residues [nucleotide binding]
1008297003714	transcriptional regulator MirA; Provisional; Region: PRK15043
1008297003715	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
1008297003716	DNA binding residues [nucleotide binding]
1008297003717	dimer interface [polypeptide binding]; other site
1008297003718	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1008297003719	chorismate mutase; Provisional; Region: PRK08055
1008297003720	potential frameshift: common BLAST hit: gi|379700439|ref|YP_005242167.1| leucine export protein LeuE
1008297003721	LysE type translocator; Region: LysE; cl00565
1008297003722	LysE type translocator; Region: LysE; cl00565
1008297003723	hypothetical protein (pseudogene)
1008297003724	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1008297003725	hypothetical protein; Provisional; Region: PRK10457
1008297003726	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1008297003727	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1008297003728	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1008297003729	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1008297003730	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1008297003731	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297003732	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1008297003733	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297003734	Predicted membrane protein [Function unknown]; Region: COG2707
1008297003735	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1008297003736	putative deacylase active site [active]
1008297003737	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1008297003738	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1008297003739	metal binding site [ion binding]; metal-binding site
1008297003740	active site
1008297003741	I-site; other site
1008297003742	hypothetical protein; Provisional; Region: PRK05325
1008297003743	PrkA family serine protein kinase; Provisional; Region: PRK15455
1008297003744	AAA ATPase domain; Region: AAA_16; pfam13191
1008297003745	Walker A motif; other site
1008297003746	ATP binding site [chemical binding]; other site
1008297003747	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1008297003748	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1008297003749	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1008297003750	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
1008297003751	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1008297003752	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1008297003753	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1008297003754	active site
1008297003755	catalytic tetrad [active]
1008297003756	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1008297003757	active site
1008297003758	phosphate binding residues; other site
1008297003759	catalytic residues [active]
1008297003760	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1008297003761	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1008297003762	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1008297003763	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1008297003764	SelR domain; Region: SelR; pfam01641
1008297003765	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1008297003766	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1008297003767	Isochorismatase family; Region: Isochorismatase; pfam00857
1008297003768	catalytic triad [active]
1008297003769	metal binding site [ion binding]; metal-binding site
1008297003770	conserved cis-peptide bond; other site
1008297003771	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1008297003772	active site
1008297003773	homodimer interface [polypeptide binding]; other site
1008297003774	protease 4; Provisional; Region: PRK10949
1008297003775	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1008297003776	tandem repeat interface [polypeptide binding]; other site
1008297003777	oligomer interface [polypeptide binding]; other site
1008297003778	active site residues [active]
1008297003779	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1008297003780	tandem repeat interface [polypeptide binding]; other site
1008297003781	oligomer interface [polypeptide binding]; other site
1008297003782	active site residues [active]
1008297003783	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1008297003784	putative FMN binding site [chemical binding]; other site
1008297003785	selenophosphate synthetase; Provisional; Region: PRK00943
1008297003786	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1008297003787	dimerization interface [polypeptide binding]; other site
1008297003788	putative ATP binding site [chemical binding]; other site
1008297003789	DNA topoisomerase III; Provisional; Region: PRK07726
1008297003790	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1008297003791	active site
1008297003792	putative interdomain interaction site [polypeptide binding]; other site
1008297003793	putative metal-binding site [ion binding]; other site
1008297003794	putative nucleotide binding site [chemical binding]; other site
1008297003795	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1008297003796	domain I; other site
1008297003797	DNA binding groove [nucleotide binding]
1008297003798	phosphate binding site [ion binding]; other site
1008297003799	domain II; other site
1008297003800	domain III; other site
1008297003801	nucleotide binding site [chemical binding]; other site
1008297003802	catalytic site [active]
1008297003803	domain IV; other site
1008297003804	glutamate dehydrogenase; Provisional; Region: PRK09414
1008297003805	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1008297003806	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1008297003807	NAD(P) binding site [chemical binding]; other site
1008297003808	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1008297003809	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1008297003810	active site
1008297003811	8-oxo-dGMP binding site [chemical binding]; other site
1008297003812	nudix motif; other site
1008297003813	metal binding site [ion binding]; metal-binding site
1008297003814	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1008297003815	putative catalytic site [active]
1008297003816	putative phosphate binding site [ion binding]; other site
1008297003817	active site
1008297003818	metal binding site A [ion binding]; metal-binding site
1008297003819	DNA binding site [nucleotide binding]
1008297003820	putative AP binding site [nucleotide binding]; other site
1008297003821	putative metal binding site B [ion binding]; other site
1008297003822	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1008297003823	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1008297003824	inhibitor-cofactor binding pocket; inhibition site
1008297003825	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297003826	catalytic residue [active]
1008297003827	arginine succinyltransferase; Provisional; Region: PRK10456
1008297003828	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
1008297003829	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1008297003830	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1008297003831	NAD(P) binding site [chemical binding]; other site
1008297003832	catalytic residues [active]
1008297003833	succinylarginine dihydrolase; Provisional; Region: PRK13281
1008297003834	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1008297003835	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1008297003836	putative active site [active]
1008297003837	Zn binding site [ion binding]; other site
1008297003838	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1008297003839	dimer interface [polypeptide binding]; other site
1008297003840	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1008297003841	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1008297003842	GIY-YIG motif/motif A; other site
1008297003843	active site
1008297003844	catalytic site [active]
1008297003845	putative DNA binding site [nucleotide binding]; other site
1008297003846	metal binding site [ion binding]; metal-binding site
1008297003847	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1008297003848	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1008297003849	homodimer interface [polypeptide binding]; other site
1008297003850	NAD binding pocket [chemical binding]; other site
1008297003851	ATP binding pocket [chemical binding]; other site
1008297003852	Mg binding site [ion binding]; other site
1008297003853	active-site loop [active]
1008297003854	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1008297003855	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1008297003856	active site
1008297003857	P-loop; other site
1008297003858	phosphorylation site [posttranslational modification]
1008297003859	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1008297003860	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1008297003861	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1008297003862	methionine cluster; other site
1008297003863	active site
1008297003864	phosphorylation site [posttranslational modification]
1008297003865	metal binding site [ion binding]; metal-binding site
1008297003866	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1008297003867	Cupin domain; Region: Cupin_2; pfam07883
1008297003868	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297003869	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1008297003870	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1008297003871	NAD binding site [chemical binding]; other site
1008297003872	sugar binding site [chemical binding]; other site
1008297003873	divalent metal binding site [ion binding]; other site
1008297003874	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1008297003875	dimer interface [polypeptide binding]; other site
1008297003876	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1008297003877	putative active site [active]
1008297003878	YdjC motif; other site
1008297003879	Mg binding site [ion binding]; other site
1008297003880	putative homodimer interface [polypeptide binding]; other site
1008297003881	hydroperoxidase II; Provisional; Region: katE; PRK11249
1008297003882	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1008297003883	tetramer interface [polypeptide binding]; other site
1008297003884	heme binding pocket [chemical binding]; other site
1008297003885	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1008297003886	domain interactions; other site
1008297003887	cell division modulator; Provisional; Region: PRK10113
1008297003888	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1008297003889	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1008297003890	inner membrane protein; Provisional; Region: PRK11648
1008297003891	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1008297003892	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297003893	motif II; other site
1008297003894	YniB-like protein; Region: YniB; pfam14002
1008297003895	Phosphotransferase enzyme family; Region: APH; pfam01636
1008297003896	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1008297003897	active site
1008297003898	ATP binding site [chemical binding]; other site
1008297003899	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1008297003900	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1008297003901	6-phosphofructokinase 2; Provisional; Region: PRK10294
1008297003902	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1008297003903	putative substrate binding site [chemical binding]; other site
1008297003904	putative ATP binding site [chemical binding]; other site
1008297003905	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1008297003906	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
1008297003907	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
1008297003908	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1008297003909	active site
1008297003910	substrate binding site [chemical binding]; other site
1008297003911	Mg2+ binding site [ion binding]; other site
1008297003912	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1008297003913	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1008297003914	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1008297003915	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1008297003916	active site
1008297003917	dimer interface [polypeptide binding]; other site
1008297003918	motif 1; other site
1008297003919	motif 2; other site
1008297003920	motif 3; other site
1008297003921	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1008297003922	anticodon binding site; other site
1008297003923	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1008297003924	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1008297003925	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1008297003926	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1008297003927	23S rRNA binding site [nucleotide binding]; other site
1008297003928	L21 binding site [polypeptide binding]; other site
1008297003929	L13 binding site [polypeptide binding]; other site
1008297003930	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1008297003931	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1008297003932	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1008297003933	dimer interface [polypeptide binding]; other site
1008297003934	motif 1; other site
1008297003935	active site
1008297003936	motif 2; other site
1008297003937	motif 3; other site
1008297003938	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1008297003939	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1008297003940	putative tRNA-binding site [nucleotide binding]; other site
1008297003941	B3/4 domain; Region: B3_4; pfam03483
1008297003942	tRNA synthetase B5 domain; Region: B5; smart00874
1008297003943	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1008297003944	dimer interface [polypeptide binding]; other site
1008297003945	motif 1; other site
1008297003946	motif 3; other site
1008297003947	motif 2; other site
1008297003948	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1008297003949	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1008297003950	IHF dimer interface [polypeptide binding]; other site
1008297003951	IHF - DNA interface [nucleotide binding]; other site
1008297003952	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1008297003953	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1008297003954	ABC-ATPase subunit  interface; other site
1008297003955	dimer interface [polypeptide binding]; other site
1008297003956	putative PBP binding regions; other site
1008297003957	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1008297003958	catalytic residues [active]
1008297003959	dimer interface [polypeptide binding]; other site
1008297003960	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
1008297003961	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1008297003962	Walker A/P-loop; other site
1008297003963	ATP binding site [chemical binding]; other site
1008297003964	Q-loop/lid; other site
1008297003965	ABC transporter signature motif; other site
1008297003966	Walker B; other site
1008297003967	D-loop; other site
1008297003968	H-loop/switch region; other site
1008297003969	NlpC/P60 family; Region: NLPC_P60; pfam00877
1008297003970	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
1008297003971	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1008297003972	hypothetical protein; Validated; Region: PRK00029
1008297003973	hypothetical protein; Provisional; Region: PRK10183
1008297003974	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1008297003975	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1008297003976	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1008297003977	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1008297003978	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1008297003979	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1008297003980	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1008297003981	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
1008297003982	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
1008297003983	acyl-activating enzyme (AAE) consensus motif; other site
1008297003984	putative AMP binding site [chemical binding]; other site
1008297003985	putative active site [active]
1008297003986	putative CoA binding site [chemical binding]; other site
1008297003987	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1008297003988	oxidoreductase; Provisional; Region: PRK10015
1008297003989	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
1008297003990	Electron transfer flavoprotein domain; Region: ETF; smart00893
1008297003991	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1008297003992	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1008297003993	Ligand binding site [chemical binding]; other site
1008297003994	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1008297003995	Cupin domain; Region: Cupin_2; pfam07883
1008297003996	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1008297003997	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297003998	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
1008297003999	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1008297004000	active site
1008297004001	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1008297004002	Coenzyme A transferase; Region: CoA_trans; smart00882
1008297004003	Coenzyme A transferase; Region: CoA_trans; cl17247
1008297004004	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1008297004005	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1008297004006	active site
1008297004007	catalytic residue [active]
1008297004008	dimer interface [polypeptide binding]; other site
1008297004009	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
1008297004010	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1008297004011	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1008297004012	shikimate binding site; other site
1008297004013	NAD(P) binding site [chemical binding]; other site
1008297004014	Putative MFS-family transport protein (pseudogene)
1008297004015	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297004016	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1008297004017	putative substrate translocation pore; other site
1008297004018	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
1008297004019	putative inner membrane protein; Provisional; Region: PRK10983
1008297004020	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1008297004021	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1008297004022	FAD binding domain; Region: FAD_binding_4; pfam01565
1008297004023	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1008297004024	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1008297004025	CoenzymeA binding site [chemical binding]; other site
1008297004026	subunit interaction site [polypeptide binding]; other site
1008297004027	PHB binding site; other site
1008297004028	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1008297004029	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1008297004030	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1008297004031	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1008297004032	putative ABC transporter; Region: ycf24; CHL00085
1008297004033	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1008297004034	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1008297004035	Walker A/P-loop; other site
1008297004036	ATP binding site [chemical binding]; other site
1008297004037	Q-loop/lid; other site
1008297004038	ABC transporter signature motif; other site
1008297004039	Walker B; other site
1008297004040	D-loop; other site
1008297004041	H-loop/switch region; other site
1008297004042	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1008297004043	FeS assembly protein SufD; Region: sufD; TIGR01981
1008297004044	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1008297004045	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1008297004046	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1008297004047	catalytic residue [active]
1008297004048	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1008297004049	L,D-transpeptidase; Provisional; Region: PRK10190
1008297004050	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1008297004051	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1008297004052	murein lipoprotein; Provisional; Region: PRK15396
1008297004053	murein lipoprotein; Provisional; Region: PRK15396
1008297004054	pyruvate kinase; Provisional; Region: PRK09206
1008297004055	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1008297004056	domain interfaces; other site
1008297004057	active site
1008297004058	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1008297004059	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1008297004060	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1008297004061	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1008297004062	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1008297004063	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297004064	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1008297004065	substrate binding site [chemical binding]; other site
1008297004066	dimer interface [polypeptide binding]; other site
1008297004067	ATP binding site [chemical binding]; other site
1008297004068	tetrathionate reductase subunit A; Provisional; Region: PRK14991
1008297004069	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
1008297004070	putative [Fe4-S4] binding site [ion binding]; other site
1008297004071	putative molybdopterin cofactor binding site [chemical binding]; other site
1008297004072	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
1008297004073	putative molybdopterin cofactor binding site; other site
1008297004074	tetrathionate reductase subunit C; Provisional; Region: PRK14992
1008297004075	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1008297004076	tetrathionate reductase subunit B; Provisional; Region: PRK14993
1008297004077	4Fe-4S binding domain; Region: Fer4; pfam00037
1008297004078	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1008297004079	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1008297004080	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1008297004081	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297004082	dimer interface [polypeptide binding]; other site
1008297004083	phosphorylation site [posttranslational modification]
1008297004084	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297004085	ATP binding site [chemical binding]; other site
1008297004086	Mg2+ binding site [ion binding]; other site
1008297004087	G-X-G motif; other site
1008297004088	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1008297004089	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297004090	active site
1008297004091	phosphorylation site [posttranslational modification]
1008297004092	intermolecular recognition site; other site
1008297004093	dimerization interface [polypeptide binding]; other site
1008297004094	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297004095	DNA binding residues [nucleotide binding]
1008297004096	dimerization interface [polypeptide binding]; other site
1008297004097	hypothetical protein; Provisional; Region: PRK10292
1008297004098	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1008297004099	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1008297004100	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
1008297004101	transcriptional regulator MirA; Provisional; Region: PRK15043
1008297004102	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1008297004103	DNA binding residues [nucleotide binding]
1008297004104	two component system sensor kinase SsrB; Provisional; Region: PRK15369
1008297004105	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297004106	active site
1008297004107	phosphorylation site [posttranslational modification]
1008297004108	intermolecular recognition site; other site
1008297004109	dimerization interface [polypeptide binding]; other site
1008297004110	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297004111	DNA binding residues [nucleotide binding]
1008297004112	dimerization interface [polypeptide binding]; other site
1008297004113	two component system sensor kinase SsrA; Provisional; Region: PRK15347
1008297004114	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297004115	dimerization interface [polypeptide binding]; other site
1008297004116	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297004117	dimer interface [polypeptide binding]; other site
1008297004118	phosphorylation site [posttranslational modification]
1008297004119	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297004120	ATP binding site [chemical binding]; other site
1008297004121	Mg2+ binding site [ion binding]; other site
1008297004122	G-X-G motif; other site
1008297004123	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297004124	active site
1008297004125	phosphorylation site [posttranslational modification]
1008297004126	intermolecular recognition site; other site
1008297004127	dimerization interface [polypeptide binding]; other site
1008297004128	outer membrane secretin SsaC; Provisional; Region: PRK15346
1008297004129	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1008297004130	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1008297004131	type III secretion system protein SsaD; Provisional; Region: PRK15367
1008297004132	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
1008297004133	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
1008297004134	EspA-like secreted protein; Region: EspA; cl04069
1008297004135	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
1008297004136	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
1008297004137	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
1008297004138	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
1008297004139	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
1008297004140	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1008297004141	TPR motif; other site
1008297004142	binding surface
1008297004143	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
1008297004144	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
1008297004145	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
1008297004146	type III secretion system protein SsaH; Provisional; Region: PRK15356
1008297004147	Type III secretion needle MxiH like; Region: MxiH; cl09641
1008297004148	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
1008297004149	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
1008297004150	type III secretion system protein SsaK; Provisional; Region: PRK15354
1008297004151	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
1008297004152	type III secretion system protein SsaL; Provisional; Region: PRK15345
1008297004153	HrpJ-like domain; Region: HrpJ; pfam07201
1008297004154	TyeA; Region: TyeA; cl07611
1008297004155	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
1008297004156	FHIPEP family; Region: FHIPEP; pfam00771
1008297004157	type III secretion system ATPase SsaN; Validated; Region: PRK07594
1008297004158	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1008297004159	Walker A motif; other site
1008297004160	ATP binding site [chemical binding]; other site
1008297004161	Walker B motif; other site
1008297004162	type III secretion system protein SsaO; Provisional; Region: PRK15352
1008297004163	type III secretion system protein SsaP; Provisional; Region: PRK15351
1008297004164	type III secretion system protein SsaQ; Validated; Region: PRK08035
1008297004165	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437
1008297004166	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1008297004167	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
1008297004168	type III secretion system protein SsaT; Provisional; Region: PRK15349
1008297004169	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
1008297004170	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1008297004171	multidrug efflux protein; Reviewed; Region: PRK01766
1008297004172	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1008297004173	cation binding site [ion binding]; other site
1008297004174	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1008297004175	Lumazine binding domain; Region: Lum_binding; pfam00677
1008297004176	Lumazine binding domain; Region: Lum_binding; pfam00677
1008297004177	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1008297004178	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297004179	S-adenosylmethionine binding site [chemical binding]; other site
1008297004180	putative transporter; Provisional; Region: PRK11043
1008297004181	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297004182	putative substrate translocation pore; other site
1008297004183	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1008297004184	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297004185	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297004186	dimerization interface [polypeptide binding]; other site
1008297004187	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1008297004188	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297004189	DNA binding site [nucleotide binding]
1008297004190	domain linker motif; other site
1008297004191	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1008297004192	dimerization interface [polypeptide binding]; other site
1008297004193	ligand binding site [chemical binding]; other site
1008297004194	superoxide dismutase; Provisional; Region: PRK10543
1008297004195	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1008297004196	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1008297004197	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1008297004198	NlpC/P60 family; Region: NLPC_P60; pfam00877
1008297004199	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1008297004200	putative GSH binding site [chemical binding]; other site
1008297004201	catalytic residues [active]
1008297004202	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1008297004203	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1008297004204	dimer interface [polypeptide binding]; other site
1008297004205	catalytic site [active]
1008297004206	putative active site [active]
1008297004207	putative substrate binding site [chemical binding]; other site
1008297004208	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1008297004209	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1008297004210	dimer interface [polypeptide binding]; other site
1008297004211	active site
1008297004212	metal binding site [ion binding]; metal-binding site
1008297004213	glutathione binding site [chemical binding]; other site
1008297004214	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1008297004215	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1008297004216	FMN binding site [chemical binding]; other site
1008297004217	active site
1008297004218	substrate binding site [chemical binding]; other site
1008297004219	catalytic residue [active]
1008297004220	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1008297004221	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297004222	Protein of unknown function (DUF1289); Region: DUF1289; cl01304
1008297004223	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1008297004224	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1008297004225	active site
1008297004226	catalytic tetrad [active]
1008297004227	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1008297004228	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1008297004229	E-class dimer interface [polypeptide binding]; other site
1008297004230	P-class dimer interface [polypeptide binding]; other site
1008297004231	active site
1008297004232	Cu2+ binding site [ion binding]; other site
1008297004233	Zn2+ binding site [ion binding]; other site
1008297004234	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1008297004235	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1008297004236	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1008297004237	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1008297004238	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297004239	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1008297004240	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1008297004241	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
1008297004242	lysozyme inhibitor; Provisional; Region: PRK11372
1008297004243	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1008297004244	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1008297004245	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1008297004246	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1008297004247	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1008297004248	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1008297004249	active site
1008297004250	HIGH motif; other site
1008297004251	dimer interface [polypeptide binding]; other site
1008297004252	KMSKS motif; other site
1008297004253	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1008297004254	RNA binding surface [nucleotide binding]; other site
1008297004255	pyridoxamine kinase; Validated; Region: PRK05756
1008297004256	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1008297004257	ATP binding site [chemical binding]; other site
1008297004258	glutathionine S-transferase; Provisional; Region: PRK10542
1008297004259	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1008297004260	C-terminal domain interface [polypeptide binding]; other site
1008297004261	GSH binding site (G-site) [chemical binding]; other site
1008297004262	dimer interface [polypeptide binding]; other site
1008297004263	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1008297004264	dimer interface [polypeptide binding]; other site
1008297004265	N-terminal domain interface [polypeptide binding]; other site
1008297004266	substrate binding pocket (H-site) [chemical binding]; other site
1008297004267	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1008297004268	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297004269	putative substrate translocation pore; other site
1008297004270	POT family; Region: PTR2; pfam00854
1008297004271	endonuclease III; Provisional; Region: PRK10702
1008297004272	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1008297004273	minor groove reading motif; other site
1008297004274	helix-hairpin-helix signature motif; other site
1008297004275	substrate binding pocket [chemical binding]; other site
1008297004276	active site
1008297004277	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1008297004278	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1008297004279	electron transport complex protein RnfG; Validated; Region: PRK01908
1008297004280	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1008297004281	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1008297004282	SLBB domain; Region: SLBB; pfam10531
1008297004283	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1008297004284	electron transport complex protein RnfB; Provisional; Region: PRK05113
1008297004285	Putative Fe-S cluster; Region: FeS; cl17515
1008297004286	4Fe-4S binding domain; Region: Fer4; pfam00037
1008297004287	electron transport complex protein RsxA; Provisional; Region: PRK05151
1008297004288	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1008297004289	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1008297004290	putative oxidoreductase; Provisional; Region: PRK11579
1008297004291	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1008297004292	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1008297004293	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1008297004294	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1008297004295	active site
1008297004296	purine riboside binding site [chemical binding]; other site
1008297004297	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1008297004298	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1008297004299	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1008297004300	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1008297004301	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1008297004302	fumarate hydratase; Provisional; Region: PRK15389
1008297004303	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1008297004304	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1008297004305	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1008297004306	Class II fumarases; Region: Fumarase_classII; cd01362
1008297004307	active site
1008297004308	tetramer interface [polypeptide binding]; other site
1008297004309	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1008297004310	sensor protein RstB; Provisional; Region: PRK10604
1008297004311	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297004312	dimerization interface [polypeptide binding]; other site
1008297004313	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297004314	dimer interface [polypeptide binding]; other site
1008297004315	phosphorylation site [posttranslational modification]
1008297004316	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297004317	ATP binding site [chemical binding]; other site
1008297004318	Mg2+ binding site [ion binding]; other site
1008297004319	G-X-G motif; other site
1008297004320	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1008297004321	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1008297004322	active site
1008297004323	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1008297004324	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1008297004325	trimer interface [polypeptide binding]; other site
1008297004326	eyelet of channel; other site
1008297004327	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1008297004328	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297004329	active site
1008297004330	phosphorylation site [posttranslational modification]
1008297004331	intermolecular recognition site; other site
1008297004332	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297004333	DNA binding site [nucleotide binding]
1008297004334	GlpM protein; Region: GlpM; pfam06942
1008297004335	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1008297004336	Spore germination protein; Region: Spore_permease; cl17796
1008297004337	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1008297004338	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1008297004339	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1008297004340	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1008297004341	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1008297004342	ligand binding site [chemical binding]; other site
1008297004343	homodimer interface [polypeptide binding]; other site
1008297004344	NAD(P) binding site [chemical binding]; other site
1008297004345	trimer interface B [polypeptide binding]; other site
1008297004346	trimer interface A [polypeptide binding]; other site
1008297004347	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1008297004348	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1008297004349	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1008297004350	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1008297004351	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1008297004352	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1008297004353	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1008297004354	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1008297004355	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1008297004356	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297004357	putative substrate translocation pore; other site
1008297004358	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1008297004359	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297004360	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1008297004361	dimerization interface [polypeptide binding]; other site
1008297004362	substrate binding pocket [chemical binding]; other site
1008297004363	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1008297004364	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1008297004365	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1008297004366	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1008297004367	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
1008297004368	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1008297004369	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1008297004370	Cl- selectivity filter; other site
1008297004371	Cl- binding residues [ion binding]; other site
1008297004372	pore gating glutamate residue; other site
1008297004373	dimer interface [polypeptide binding]; other site
1008297004374	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1008297004375	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1008297004376	Walker A/P-loop; other site
1008297004377	ATP binding site [chemical binding]; other site
1008297004378	Q-loop/lid; other site
1008297004379	ABC transporter signature motif; other site
1008297004380	Walker B; other site
1008297004381	D-loop; other site
1008297004382	H-loop/switch region; other site
1008297004383	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
1008297004384	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297004385	dimer interface [polypeptide binding]; other site
1008297004386	conserved gate region; other site
1008297004387	ABC-ATPase subunit interface; other site
1008297004388	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1008297004389	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297004390	dimer interface [polypeptide binding]; other site
1008297004391	conserved gate region; other site
1008297004392	putative PBP binding loops; other site
1008297004393	ABC-ATPase subunit interface; other site
1008297004394	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1008297004395	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1008297004396	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1008297004397	4Fe-4S binding domain; Region: Fer4; pfam00037
1008297004398	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1008297004399	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1008297004400	putative [Fe4-S4] binding site [ion binding]; other site
1008297004401	putative molybdopterin cofactor binding site [chemical binding]; other site
1008297004402	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1008297004403	putative molybdopterin cofactor binding site; other site
1008297004404	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1008297004405	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1008297004406	putative [Fe4-S4] binding site [ion binding]; other site
1008297004407	putative molybdopterin cofactor binding site [chemical binding]; other site
1008297004408	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1008297004409	putative molybdopterin cofactor binding site; other site
1008297004410	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1008297004411	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
1008297004412	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1008297004413	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297004414	Coenzyme A binding pocket [chemical binding]; other site
1008297004415	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1008297004416	hypothetical protein; Provisional; Region: PRK13659
1008297004417	hypothetical protein; Provisional; Region: PRK02237
1008297004418	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1008297004419	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1008297004420	putative active site pocket [active]
1008297004421	putative metal binding site [ion binding]; other site
1008297004422	putative oxidoreductase; Provisional; Region: PRK10083
1008297004423	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1008297004424	putative NAD(P) binding site [chemical binding]; other site
1008297004425	catalytic Zn binding site [ion binding]; other site
1008297004426	structural Zn binding site [ion binding]; other site
1008297004427	putative membrane transport protein (pseudogene)
1008297004428	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1008297004429	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1008297004430	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1008297004431	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
1008297004432	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1008297004433	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297004434	DNA-binding site [nucleotide binding]; DNA binding site
1008297004435	FCD domain; Region: FCD; pfam07729
1008297004436	malonic semialdehyde reductase; Provisional; Region: PRK10538
1008297004437	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1008297004438	putative NAD(P) binding site [chemical binding]; other site
1008297004439	homodimer interface [polypeptide binding]; other site
1008297004440	homotetramer interface [polypeptide binding]; other site
1008297004441	active site
1008297004442	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1008297004443	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1008297004444	active site
1008297004445	Zn binding site [ion binding]; other site
1008297004446	General stress protein [General function prediction only]; Region: GsiB; COG3729
1008297004447	hypothetical protein; Validated; Region: PRK03657
1008297004448	hypothetical protein; Provisional; Region: PRK10053
1008297004449	putative transporter; Provisional; Region: PRK10054
1008297004450	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297004451	putative substrate translocation pore; other site
1008297004452	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1008297004453	EamA-like transporter family; Region: EamA; pfam00892
1008297004454	MarB protein; Region: MarB; pfam13999
1008297004455	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
1008297004456	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297004457	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297004458	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
1008297004459	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1008297004460	inner membrane protein; Provisional; Region: PRK10995
1008297004461	putative arabinose transporter; Provisional; Region: PRK03545
1008297004462	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297004463	putative substrate translocation pore; other site
1008297004464	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297004465	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297004466	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1008297004467	putative dimerization interface [polypeptide binding]; other site
1008297004468	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
1008297004469	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1008297004470	NAD(P) binding site [chemical binding]; other site
1008297004471	catalytic residues [active]
1008297004472	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1008297004473	glutaminase; Provisional; Region: PRK00971
1008297004474	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1008297004475	Predicted membrane protein [Function unknown]; Region: COG3781
1008297004476	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1008297004477	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1008297004478	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1008297004479	trimer interface [polypeptide binding]; other site
1008297004480	eyelet of channel; other site
1008297004481	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1008297004482	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1008297004483	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
1008297004484	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1008297004485	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1008297004486	Rubredoxin [Energy production and conversion]; Region: COG1773
1008297004487	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1008297004488	iron binding site [ion binding]; other site
1008297004489	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1008297004490	HupF/HypC family; Region: HupF_HypC; cl00394
1008297004491	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1008297004492	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1008297004493	putative substrate-binding site; other site
1008297004494	nickel binding site [ion binding]; other site
1008297004495	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
1008297004496	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1008297004497	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1008297004498	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
1008297004499	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1008297004500	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1008297004501	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
1008297004502	active site
1008297004503	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1008297004504	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297004505	DNA-binding site [nucleotide binding]; DNA binding site
1008297004506	FCD domain; Region: FCD; pfam07729
1008297004507	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1008297004508	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1008297004509	putative NAD(P) binding site [chemical binding]; other site
1008297004510	catalytic Zn binding site [ion binding]; other site
1008297004511	structural Zn binding site [ion binding]; other site
1008297004512	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297004513	D-galactonate transporter; Region: 2A0114; TIGR00893
1008297004514	putative substrate translocation pore; other site
1008297004515	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
1008297004516	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297004517	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1008297004518	putative substrate translocation pore; other site
1008297004519	hypothetical protein; Provisional; Region: PRK06184
1008297004520	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1008297004521	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1008297004522	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1008297004523	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1008297004524	putative DNA binding site [nucleotide binding]; other site
1008297004525	putative Zn2+ binding site [ion binding]; other site
1008297004526	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
1008297004527	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1008297004528	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
1008297004529	homotrimer interaction site [polypeptide binding]; other site
1008297004530	putative active site [active]
1008297004531	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1008297004532	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1008297004533	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1008297004534	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297004535	DNA binding site [nucleotide binding]
1008297004536	domain linker motif; other site
1008297004537	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1008297004538	dimerization interface (closed form) [polypeptide binding]; other site
1008297004539	ligand binding site [chemical binding]; other site
1008297004540	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
1008297004541	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1008297004542	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297004543	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297004544	homodimer interface [polypeptide binding]; other site
1008297004545	catalytic residue [active]
1008297004546	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1008297004547	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1008297004548	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1008297004549	active site
1008297004550	catalytic site [active]
1008297004551	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
1008297004552	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1008297004553	active site
1008297004554	catalytic site [active]
1008297004555	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1008297004556	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
1008297004557	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
1008297004558	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
1008297004559	catalytic site [active]
1008297004560	active site
1008297004561	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
1008297004562	acid-resistance protein; Provisional; Region: hdeB; PRK11566
1008297004563	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1008297004564	biofilm-dependent modulation protein; Provisional; Region: PRK11436
1008297004565	malate dehydrogenase; Provisional; Region: PRK13529
1008297004566	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1008297004567	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1008297004568	NAD(P) binding site [chemical binding]; other site
1008297004569	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1008297004570	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1008297004571	NAD binding site [chemical binding]; other site
1008297004572	substrate binding site [chemical binding]; other site
1008297004573	catalytic Zn binding site [ion binding]; other site
1008297004574	tetramer interface [polypeptide binding]; other site
1008297004575	structural Zn binding site [ion binding]; other site
1008297004576	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
1008297004577	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1008297004578	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1008297004579	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1008297004580	potential frameshift: common BLAST hit: gi|379700741|ref|YP_005242469.1| formate dehydrogenase-N subunit alpha
1008297004581	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297004582	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297004583	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1008297004584	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1008297004585	molybdopterin cofactor binding site; other site
1008297004586	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297004587	aromatic amino acid exporter; Provisional; Region: PRK11689
1008297004588	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1008297004589	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1008297004590	trimer interface [polypeptide binding]; other site
1008297004591	eyelet of channel; other site
1008297004592	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1008297004593	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1008297004594	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297004595	putative substrate translocation pore; other site
1008297004596	TetR family transcriptional regulator; Provisional; Region: PRK14996
1008297004597	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297004598	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1008297004599	potential frameshift: common BLAST hit: gi|379700748|ref|YP_005242476.1| nitrate reductase 2 alpha subunit
1008297004600	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1008297004601	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1008297004602	[4Fe-4S] binding site [ion binding]; other site
1008297004603	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297004604	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297004605	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1008297004606	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297004607	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297004608	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1008297004609	molybdopterin cofactor binding site; other site
1008297004610	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1008297004611	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
1008297004612	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1008297004613	hypothetical protein; Provisional; Region: PRK10281
1008297004614	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
1008297004615	L-asparagine permease; Provisional; Region: PRK15049
1008297004616	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1008297004617	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1008297004618	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1008297004619	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1008297004620	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1008297004621	N-terminal plug; other site
1008297004622	ligand-binding site [chemical binding]; other site
1008297004623	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
1008297004624	DNA-binding site [nucleotide binding]; DNA binding site
1008297004625	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1008297004626	FCD domain; Region: FCD; pfam07729
1008297004627	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1008297004628	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1008297004629	NAD(P) binding site [chemical binding]; other site
1008297004630	substrate binding site [chemical binding]; other site
1008297004631	dimer interface [polypeptide binding]; other site
1008297004632	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1008297004633	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1008297004634	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1008297004635	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1008297004636	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
1008297004637	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
1008297004638	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1008297004639	1-pyrroline dehydrogenase; Region: ABALDH; TIGR03374
1008297004640	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
1008297004641	tetrameric interface [polypeptide binding]; other site
1008297004642	NAD binding site [chemical binding]; other site
1008297004643	catalytic residues [active]
1008297004644	substrate binding site [chemical binding]; other site
1008297004645	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1008297004646	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297004647	DNA-binding site [nucleotide binding]; DNA binding site
1008297004648	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297004649	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297004650	homodimer interface [polypeptide binding]; other site
1008297004651	catalytic residue [active]
1008297004652	D-alanyl-D-alanine dipeptidase [Cell envelope biogenesis, outer membrane]; Region: DdpX; COG2173
1008297004653	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
1008297004654	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
1008297004655	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1008297004656	Peptidase family U32; Region: Peptidase_U32; pfam01136
1008297004657	Collagenase; Region: DUF3656; pfam12392
1008297004658	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1008297004659	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1008297004660	non-specific DNA binding site [nucleotide binding]; other site
1008297004661	salt bridge; other site
1008297004662	sequence-specific DNA binding site [nucleotide binding]; other site
1008297004663	Cupin domain; Region: Cupin_2; pfam07883
1008297004664	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
1008297004665	benzoate transporter; Region: benE; TIGR00843
1008297004666	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1008297004667	tellurite resistance protein TehB; Provisional; Region: PRK11207
1008297004668	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297004669	S-adenosylmethionine binding site [chemical binding]; other site
1008297004670	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1008297004671	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1008297004672	gating phenylalanine in ion channel; other site
1008297004673	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1008297004674	putative trimer interface [polypeptide binding]; other site
1008297004675	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1008297004676	putative trimer interface [polypeptide binding]; other site
1008297004677	putative CoA binding site [chemical binding]; other site
1008297004678	putative CoA binding site [chemical binding]; other site
1008297004679	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1008297004680	putative trimer interface [polypeptide binding]; other site
1008297004681	putative CoA binding site [chemical binding]; other site
1008297004682	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1008297004683	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297004684	Coenzyme A binding pocket [chemical binding]; other site
1008297004685	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1008297004686	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1008297004687	oligomer interface [polypeptide binding]; other site
1008297004688	active site
1008297004689	metal binding site [ion binding]; metal-binding site
1008297004690	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1008297004691	active site
1008297004692	P-loop; other site
1008297004693	phosphorylation site [posttranslational modification]
1008297004694	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1008297004695	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
1008297004696	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
1008297004697	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297004698	active site
1008297004699	phosphorylation site [posttranslational modification]
1008297004700	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1008297004701	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1008297004702	substrate binding site [chemical binding]; other site
1008297004703	hexamer interface [polypeptide binding]; other site
1008297004704	metal binding site [ion binding]; metal-binding site
1008297004705	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1008297004706	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1008297004707	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297004708	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1008297004709	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297004710	Coenzyme A binding pocket [chemical binding]; other site
1008297004711	L-lactate oxidase; Region: L_lactate_ox; TIGR02708
1008297004712	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
1008297004713	teramer interface [polypeptide binding]; other site
1008297004714	active site
1008297004715	FMN binding site [chemical binding]; other site
1008297004716	catalytic residues [active]
1008297004717	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1008297004718	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1008297004719	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1008297004720	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1008297004721	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1008297004722	substrate binding pocket [chemical binding]; other site
1008297004723	catalytic triad [active]
1008297004724	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1008297004725	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1008297004726	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1008297004727	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297004728	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297004729	dimerization interface [polypeptide binding]; other site
1008297004730	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1008297004731	dimer interface [polypeptide binding]; other site
1008297004732	ligand binding site [chemical binding]; other site
1008297004733	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1008297004734	HAMP domain; Region: HAMP; pfam00672
1008297004735	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1008297004736	dimer interface [polypeptide binding]; other site
1008297004737	putative CheW interface [polypeptide binding]; other site
1008297004738	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1008297004739	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1008297004740	substrate binding site [chemical binding]; other site
1008297004741	catalytic Zn binding site [ion binding]; other site
1008297004742	NAD binding site [chemical binding]; other site
1008297004743	structural Zn binding site [ion binding]; other site
1008297004744	dimer interface [polypeptide binding]; other site
1008297004745	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1008297004746	putative metal binding site [ion binding]; other site
1008297004747	putative homodimer interface [polypeptide binding]; other site
1008297004748	putative homotetramer interface [polypeptide binding]; other site
1008297004749	putative homodimer-homodimer interface [polypeptide binding]; other site
1008297004750	putative allosteric switch controlling residues; other site
1008297004751	Sif protein; Region: Sif; cl11505
1008297004752	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1008297004753	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
1008297004754	active site
1008297004755	catalytic triad [active]
1008297004756	oxyanion hole [active]
1008297004757	Predicted membrane protein [Function unknown]; Region: COG3326
1008297004758	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297004759	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1008297004760	substrate binding pocket [chemical binding]; other site
1008297004761	membrane-bound complex binding site; other site
1008297004762	hinge residues; other site
1008297004763	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1008297004764	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297004765	dimer interface [polypeptide binding]; other site
1008297004766	conserved gate region; other site
1008297004767	putative PBP binding loops; other site
1008297004768	ABC-ATPase subunit interface; other site
1008297004769	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1008297004770	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297004771	Walker A/P-loop; other site
1008297004772	ATP binding site [chemical binding]; other site
1008297004773	Q-loop/lid; other site
1008297004774	ABC transporter signature motif; other site
1008297004775	Walker B; other site
1008297004776	D-loop; other site
1008297004777	H-loop/switch region; other site
1008297004778	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1008297004779	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297004780	dimer interface [polypeptide binding]; other site
1008297004781	conserved gate region; other site
1008297004782	putative PBP binding loops; other site
1008297004783	ABC-ATPase subunit interface; other site
1008297004784	Predicted membrane protein [Function unknown]; Region: COG5305
1008297004785	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1008297004786	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297004787	S-adenosylmethionine binding site [chemical binding]; other site
1008297004788	cytochrome b561; Provisional; Region: PRK11513
1008297004789	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1008297004790	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1008297004791	putative active site [active]
1008297004792	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1008297004793	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1008297004794	ATP binding site [chemical binding]; other site
1008297004795	putative Mg++ binding site [ion binding]; other site
1008297004796	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297004797	nucleotide binding region [chemical binding]; other site
1008297004798	ATP-binding site [chemical binding]; other site
1008297004799	Helicase associated domain (HA2); Region: HA2; pfam04408
1008297004800	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1008297004801	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1008297004802	azoreductase; Reviewed; Region: PRK00170
1008297004803	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1008297004804	Glutathione-dependent formaldehyde-activating enzyme; Region: GFA; cl01553
1008297004805	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1008297004806	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1008297004807	hypothetical protein; Provisional; Region: PRK10695
1008297004808	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1008297004809	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1008297004810	putative ligand binding site [chemical binding]; other site
1008297004811	putative NAD binding site [chemical binding]; other site
1008297004812	catalytic site [active]
1008297004813	heat-inducible protein; Provisional; Region: PRK10449
1008297004814	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1008297004815	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1008297004816	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1008297004817	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1008297004818	dimer interface [polypeptide binding]; other site
1008297004819	PYR/PP interface [polypeptide binding]; other site
1008297004820	TPP binding site [chemical binding]; other site
1008297004821	substrate binding site [chemical binding]; other site
1008297004822	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1008297004823	Domain of unknown function; Region: EKR; smart00890
1008297004824	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1008297004825	4Fe-4S binding domain; Region: Fer4; pfam00037
1008297004826	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1008297004827	TPP-binding site [chemical binding]; other site
1008297004828	dimer interface [polypeptide binding]; other site
1008297004829	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1008297004830	Ligand Binding Site [chemical binding]; other site
1008297004831	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1008297004832	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1008297004833	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1008297004834	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1008297004835	Ligand Binding Site [chemical binding]; other site
1008297004836	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1008297004837	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1008297004838	ATP binding site [chemical binding]; other site
1008297004839	Mg++ binding site [ion binding]; other site
1008297004840	motif III; other site
1008297004841	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297004842	nucleotide binding region [chemical binding]; other site
1008297004843	ATP-binding site [chemical binding]; other site
1008297004844	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1008297004845	putative RNA binding site [nucleotide binding]; other site
1008297004846	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1008297004847	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1008297004848	Cl binding site [ion binding]; other site
1008297004849	oligomer interface [polypeptide binding]; other site
1008297004850	HAMP domain; Region: HAMP; pfam00672
1008297004851	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1008297004852	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1008297004853	dimer interface [polypeptide binding]; other site
1008297004854	putative CheW interface [polypeptide binding]; other site
1008297004855	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1008297004856	Smr domain; Region: Smr; pfam01713
1008297004857	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1008297004858	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1008297004859	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1008297004860	DNA binding site [nucleotide binding]
1008297004861	active site
1008297004862	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1008297004863	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1008297004864	ligand binding site [chemical binding]; other site
1008297004865	flexible hinge region; other site
1008297004866	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1008297004867	putative switch regulator; other site
1008297004868	non-specific DNA interactions [nucleotide binding]; other site
1008297004869	DNA binding site [nucleotide binding]
1008297004870	sequence specific DNA binding site [nucleotide binding]; other site
1008297004871	putative cAMP binding site [chemical binding]; other site
1008297004872	universal stress protein UspE; Provisional; Region: PRK11175
1008297004873	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1008297004874	Ligand Binding Site [chemical binding]; other site
1008297004875	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1008297004876	Ligand Binding Site [chemical binding]; other site
1008297004877	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1008297004878	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1008297004879	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1008297004880	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1008297004881	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1008297004882	non-specific DNA binding site [nucleotide binding]; other site
1008297004883	salt bridge; other site
1008297004884	sequence-specific DNA binding site [nucleotide binding]; other site
1008297004885	Cupin domain; Region: Cupin_2; pfam07883
1008297004886	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1008297004887	B3/4 domain; Region: B3_4; pfam03483
1008297004888	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: Tpx; COG2077
1008297004889	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1008297004890	putative transcriptional regulator (pseudogene)
1008297004891	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1008297004892	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1008297004893	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297004894	oxidoreductase; Provisional; Region: PRK12742
1008297004895	classical (c) SDRs; Region: SDR_c; cd05233
1008297004896	NAD(P) binding site [chemical binding]; other site
1008297004897	active site
1008297004898	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1008297004899	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1008297004900	active site
1008297004901	catalytic tetrad [active]
1008297004902	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297004903	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297004904	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1008297004905	putative effector binding pocket; other site
1008297004906	putative dimerization interface [polypeptide binding]; other site
1008297004907	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
1008297004908	NmrA-like family; Region: NmrA; pfam05368
1008297004909	NAD(P) binding site [chemical binding]; other site
1008297004910	active site lysine
1008297004911	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1008297004912	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1008297004913	peptide binding site [polypeptide binding]; other site
1008297004914	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
1008297004915	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
1008297004916	putative active site [active]
1008297004917	Zn binding site [ion binding]; other site
1008297004918	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1008297004919	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1008297004920	active site
1008297004921	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1008297004922	dimer interface [polypeptide binding]; other site
1008297004923	catalytic triad [active]
1008297004924	peroxidatic and resolving cysteines [active]
1008297004925	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1008297004926	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1008297004927	putative aromatic amino acid binding site; other site
1008297004928	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297004929	Walker A motif; other site
1008297004930	ATP binding site [chemical binding]; other site
1008297004931	Walker B motif; other site
1008297004932	arginine finger; other site
1008297004933	hypothetical protein; Provisional; Region: PRK05415
1008297004934	TIGR01620 family protein; Region: hyp_HI0043
1008297004935	Predicted ATPase [General function prediction only]; Region: COG3106
1008297004936	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1008297004937	active site residue [active]
1008297004938	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1008297004939	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1008297004940	phage shock protein C; Region: phageshock_pspC; TIGR02978
1008297004941	phage shock protein B; Provisional; Region: pspB; PRK09458
1008297004942	phage shock protein PspA; Provisional; Region: PRK10698
1008297004943	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1008297004944	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297004945	Walker A motif; other site
1008297004946	ATP binding site [chemical binding]; other site
1008297004947	Walker B motif; other site
1008297004948	arginine finger; other site
1008297004949	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1008297004950	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1008297004951	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1008297004952	peptide binding site [polypeptide binding]; other site
1008297004953	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1008297004954	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297004955	dimer interface [polypeptide binding]; other site
1008297004956	conserved gate region; other site
1008297004957	putative PBP binding loops; other site
1008297004958	ABC-ATPase subunit interface; other site
1008297004959	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1008297004960	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1008297004961	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297004962	dimer interface [polypeptide binding]; other site
1008297004963	conserved gate region; other site
1008297004964	putative PBP binding loops; other site
1008297004965	ABC-ATPase subunit interface; other site
1008297004966	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1008297004967	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297004968	Walker A/P-loop; other site
1008297004969	ATP binding site [chemical binding]; other site
1008297004970	Q-loop/lid; other site
1008297004971	ABC transporter signature motif; other site
1008297004972	Walker B; other site
1008297004973	D-loop; other site
1008297004974	H-loop/switch region; other site
1008297004975	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1008297004976	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1008297004977	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297004978	Walker A/P-loop; other site
1008297004979	ATP binding site [chemical binding]; other site
1008297004980	Q-loop/lid; other site
1008297004981	ABC transporter signature motif; other site
1008297004982	Walker B; other site
1008297004983	D-loop; other site
1008297004984	H-loop/switch region; other site
1008297004985	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1008297004986	Protein kinase domain; Region: Pkinase; pfam00069
1008297004987	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1008297004988	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1008297004989	NAD binding site [chemical binding]; other site
1008297004990	homotetramer interface [polypeptide binding]; other site
1008297004991	homodimer interface [polypeptide binding]; other site
1008297004992	substrate binding site [chemical binding]; other site
1008297004993	active site
1008297004994	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
1008297004995	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1008297004996	exoribonuclease II; Provisional; Region: PRK05054
1008297004997	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1008297004998	RNB domain; Region: RNB; pfam00773
1008297004999	S1 RNA binding domain; Region: S1; pfam00575
1008297005000	RNase II stability modulator; Provisional; Region: PRK10060
1008297005001	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1008297005002	putative active site [active]
1008297005003	heme pocket [chemical binding]; other site
1008297005004	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1008297005005	metal binding site [ion binding]; metal-binding site
1008297005006	active site
1008297005007	I-site; other site
1008297005008	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297005009	hypothetical protein; Provisional; Region: PRK13658
1008297005010	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1008297005011	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1008297005012	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297005013	lipoprotein; Provisional; Region: PRK10540
1008297005014	translation initiation factor Sui1; Validated; Region: PRK06824
1008297005015	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1008297005016	putative rRNA binding site [nucleotide binding]; other site
1008297005017	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1008297005018	active site
1008297005019	dimer interface [polypeptide binding]; other site
1008297005020	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1008297005021	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1008297005022	TPR motif; other site
1008297005023	binding surface
1008297005024	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1008297005025	binding surface
1008297005026	TPR motif; other site
1008297005027	Predicted membrane protein [Function unknown]; Region: COG3771
1008297005028	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1008297005029	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1008297005030	active site
1008297005031	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1008297005032	dimerization interface [polypeptide binding]; other site
1008297005033	active site
1008297005034	aconitate hydratase; Validated; Region: PRK09277
1008297005035	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1008297005036	substrate binding site [chemical binding]; other site
1008297005037	ligand binding site [chemical binding]; other site
1008297005038	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1008297005039	substrate binding site [chemical binding]; other site
1008297005040	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1008297005041	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297005042	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1008297005043	substrate binding site [chemical binding]; other site
1008297005044	putative dimerization interface [polypeptide binding]; other site
1008297005045	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1008297005046	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1008297005047	active site
1008297005048	interdomain interaction site; other site
1008297005049	putative metal-binding site [ion binding]; other site
1008297005050	nucleotide binding site [chemical binding]; other site
1008297005051	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1008297005052	domain I; other site
1008297005053	DNA binding groove [nucleotide binding]
1008297005054	phosphate binding site [ion binding]; other site
1008297005055	domain II; other site
1008297005056	domain III; other site
1008297005057	nucleotide binding site [chemical binding]; other site
1008297005058	catalytic site [active]
1008297005059	domain IV; other site
1008297005060	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1008297005061	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1008297005062	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1008297005063	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1008297005064	hypothetical protein; Provisional; Region: PRK11037
1008297005065	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1008297005066	putative inner membrane peptidase; Provisional; Region: PRK11778
1008297005067	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1008297005068	tandem repeat interface [polypeptide binding]; other site
1008297005069	oligomer interface [polypeptide binding]; other site
1008297005070	active site residues [active]
1008297005071	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1008297005072	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1008297005073	NADP binding site [chemical binding]; other site
1008297005074	homodimer interface [polypeptide binding]; other site
1008297005075	active site
1008297005076	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1008297005077	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
1008297005078	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1008297005079	homodimer interface [polypeptide binding]; other site
1008297005080	Walker A motif; other site
1008297005081	ATP binding site [chemical binding]; other site
1008297005082	hydroxycobalamin binding site [chemical binding]; other site
1008297005083	Walker B motif; other site
1008297005084	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1008297005085	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1008297005086	RNA binding surface [nucleotide binding]; other site
1008297005087	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1008297005088	probable active site [active]
1008297005089	hypothetical protein; Provisional; Region: PRK11630
1008297005090	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1008297005091	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1008297005092	active site
1008297005093	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1008297005094	anthranilate synthase component I; Provisional; Region: PRK13564
1008297005095	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1008297005096	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1008297005097	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
1008297005098	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1008297005099	glutamine binding [chemical binding]; other site
1008297005100	catalytic triad [active]
1008297005101	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1008297005102	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1008297005103	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1008297005104	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1008297005105	active site
1008297005106	ribulose/triose binding site [chemical binding]; other site
1008297005107	phosphate binding site [ion binding]; other site
1008297005108	substrate (anthranilate) binding pocket [chemical binding]; other site
1008297005109	product (indole) binding pocket [chemical binding]; other site
1008297005110	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1008297005111	active site
1008297005112	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1008297005113	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1008297005114	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297005115	catalytic residue [active]
1008297005116	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1008297005117	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1008297005118	substrate binding site [chemical binding]; other site
1008297005119	active site
1008297005120	catalytic residues [active]
1008297005121	heterodimer interface [polypeptide binding]; other site
1008297005122	General stress protein [General function prediction only]; Region: GsiB; COG3729
1008297005123	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
1008297005124	dimerization interface [polypeptide binding]; other site
1008297005125	metal binding site [ion binding]; metal-binding site
1008297005126	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1008297005127	dinuclear metal binding motif [ion binding]; other site
1008297005128	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1008297005129	dimanganese center [ion binding]; other site
1008297005130	outer membrane protein W; Provisional; Region: PRK10959
1008297005131	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1008297005132	hypothetical protein; Provisional; Region: PRK02868
1008297005133	intracellular septation protein A; Reviewed; Region: PRK00259
1008297005134	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1008297005135	transport protein TonB; Provisional; Region: PRK10819
1008297005136	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1008297005137	YciI-like protein; Reviewed; Region: PRK11370
1008297005138	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1008297005139	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1008297005140	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1008297005141	putative active site [active]
1008297005142	catalytic site [active]
1008297005143	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1008297005144	putative active site [active]
1008297005145	catalytic site [active]
1008297005146	dsDNA-mimic protein; Reviewed; Region: PRK05094
1008297005147	Ion transport protein; Region: Ion_trans; pfam00520
1008297005148	Ion channel; Region: Ion_trans_2; pfam07885
1008297005149	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1008297005150	Double zinc ribbon; Region: DZR; pfam12773
1008297005151	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1008297005152	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297005153	Walker A/P-loop; other site
1008297005154	ATP binding site [chemical binding]; other site
1008297005155	Q-loop/lid; other site
1008297005156	ABC transporter signature motif; other site
1008297005157	Walker B; other site
1008297005158	D-loop; other site
1008297005159	H-loop/switch region; other site
1008297005160	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1008297005161	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1008297005162	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297005163	Walker A/P-loop; other site
1008297005164	ATP binding site [chemical binding]; other site
1008297005165	Q-loop/lid; other site
1008297005166	ABC transporter signature motif; other site
1008297005167	Walker B; other site
1008297005168	D-loop; other site
1008297005169	H-loop/switch region; other site
1008297005170	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1008297005171	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1008297005172	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1008297005173	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297005174	dimer interface [polypeptide binding]; other site
1008297005175	conserved gate region; other site
1008297005176	ABC-ATPase subunit interface; other site
1008297005177	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1008297005178	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297005179	dimer interface [polypeptide binding]; other site
1008297005180	conserved gate region; other site
1008297005181	putative PBP binding loops; other site
1008297005182	ABC-ATPase subunit interface; other site
1008297005183	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1008297005184	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1008297005185	peptide binding site [polypeptide binding]; other site
1008297005186	hypothetical protein; Provisional; Region: PRK11111
1008297005187	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1008297005188	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1008297005189	putative catalytic cysteine [active]
1008297005190	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1008297005191	putative active site [active]
1008297005192	metal binding site [ion binding]; metal-binding site
1008297005193	thymidine kinase; Provisional; Region: PRK04296
1008297005194	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1008297005195	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1008297005196	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1008297005197	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1008297005198	active site
1008297005199	tetramer interface; other site
1008297005200	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297005201	active site
1008297005202	response regulator of RpoS; Provisional; Region: PRK10693
1008297005203	phosphorylation site [posttranslational modification]
1008297005204	intermolecular recognition site; other site
1008297005205	dimerization interface [polypeptide binding]; other site
1008297005206	hypothetical protein; Provisional; Region: PRK10279
1008297005207	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1008297005208	active site
1008297005209	nucleophile elbow; other site
1008297005210	hypothetical protein; Provisional; Region: PRK01617
1008297005211	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1008297005212	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1008297005213	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1008297005214	putative active site [active]
1008297005215	putative substrate binding site [chemical binding]; other site
1008297005216	putative cosubstrate binding site; other site
1008297005217	catalytic site [active]
1008297005218	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1008297005219	Sel1-like repeats; Region: SEL1; smart00671
1008297005220	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1008297005221	Sel1-like repeats; Region: SEL1; smart00671
1008297005222	Sel1-like repeats; Region: SEL1; smart00671
1008297005223	Sel1-like repeats; Region: SEL1; smart00671
1008297005224	Sel1-like repeats; Region: SEL1; smart00671
1008297005225	Sel1-like repeats; Region: SEL1; smart00671
1008297005226	Sel1-like repeats; Region: SEL1; smart00671
1008297005227	Sel1-like repeats; Region: SEL1; smart00671
1008297005228	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1008297005229	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1008297005230	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1008297005231	4Fe-4S binding domain; Region: Fer4; cl02805
1008297005232	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1008297005233	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1008297005234	[4Fe-4S] binding site [ion binding]; other site
1008297005235	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297005236	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297005237	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297005238	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1008297005239	molybdopterin cofactor binding site; other site
1008297005240	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1008297005241	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1008297005242	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1008297005243	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297005244	dimerization interface [polypeptide binding]; other site
1008297005245	Histidine kinase; Region: HisKA_3; pfam07730
1008297005246	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297005247	ATP binding site [chemical binding]; other site
1008297005248	Mg2+ binding site [ion binding]; other site
1008297005249	G-X-G motif; other site
1008297005250	transcriptional regulator NarL; Provisional; Region: PRK10651
1008297005251	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297005252	active site
1008297005253	phosphorylation site [posttranslational modification]
1008297005254	intermolecular recognition site; other site
1008297005255	dimerization interface [polypeptide binding]; other site
1008297005256	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297005257	DNA binding residues [nucleotide binding]
1008297005258	dimerization interface [polypeptide binding]; other site
1008297005259	putative invasin; Provisional; Region: PRK10177
1008297005260	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1008297005261	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1008297005262	cation transport regulator; Reviewed; Region: chaB; PRK09582
1008297005263	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1008297005264	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1008297005265	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
1008297005266	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1008297005267	hypothetical protein; Provisional; Region: PRK10941
1008297005268	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1008297005269	hypothetical protein; Provisional; Region: PRK10278
1008297005270	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1008297005271	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297005272	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1008297005273	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1008297005274	RF-1 domain; Region: RF-1; pfam00472
1008297005275	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1008297005276	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1008297005277	tRNA; other site
1008297005278	putative tRNA binding site [nucleotide binding]; other site
1008297005279	putative NADP binding site [chemical binding]; other site
1008297005280	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1008297005281	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
1008297005282	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1008297005283	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1008297005284	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1008297005285	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1008297005286	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1008297005287	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1008297005288	active site
1008297005289	putative transporter; Provisional; Region: PRK11660
1008297005290	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1008297005291	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1008297005292	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1008297005293	hypothetical protein; Provisional; Region: PRK10692
1008297005294	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1008297005295	putative active site [active]
1008297005296	catalytic residue [active]
1008297005297	GTP-binding protein YchF; Reviewed; Region: PRK09601
1008297005298	YchF GTPase; Region: YchF; cd01900
1008297005299	G1 box; other site
1008297005300	GTP/Mg2+ binding site [chemical binding]; other site
1008297005301	Switch I region; other site
1008297005302	G2 box; other site
1008297005303	Switch II region; other site
1008297005304	G3 box; other site
1008297005305	G4 box; other site
1008297005306	G5 box; other site
1008297005307	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1008297005308	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
1008297005309	Protein of unknown function (DUF4427); Region: DUF4427; pfam14468
1008297005310	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1008297005311	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1008297005312	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1008297005313	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1008297005314	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1008297005315	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
1008297005316	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1008297005317	putative substrate-binding site; other site
1008297005318	nickel binding site [ion binding]; other site
1008297005319	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1008297005320	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1008297005321	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1008297005322	cytochrome bd-II oxidase subunit I (pseudogene)
1008297005323	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
1008297005324	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1008297005325	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1008297005326	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1008297005327	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1008297005328	NAD(P) binding site [chemical binding]; other site
1008297005329	trehalase; Provisional; Region: treA; PRK13271
1008297005330	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1008297005331	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
1008297005332	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1008297005333	Flagellar regulator YcgR; Region: YcgR; pfam07317
1008297005334	PilZ domain; Region: PilZ; pfam07238
1008297005335	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1008297005336	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1008297005337	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1008297005338	catalytic residue [active]
1008297005339	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1008297005340	dimer interface [polypeptide binding]; other site
1008297005341	catalytic triad [active]
1008297005342	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1008297005343	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1008297005344	TrkA-C domain; Region: TrkA_C; pfam02080
1008297005345	Transporter associated domain; Region: CorC_HlyC; smart01091
1008297005346	alanine racemase; Reviewed; Region: dadX; PRK03646
1008297005347	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1008297005348	active site
1008297005349	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1008297005350	substrate binding site [chemical binding]; other site
1008297005351	catalytic residues [active]
1008297005352	dimer interface [polypeptide binding]; other site
1008297005353	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1008297005354	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1008297005355	SpoVR family protein; Provisional; Region: PRK11767
1008297005356	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1008297005357	fatty acid metabolism regulator; Provisional; Region: PRK04984
1008297005358	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297005359	DNA-binding site [nucleotide binding]; DNA binding site
1008297005360	FadR C-terminal domain; Region: FadR_C; pfam07840
1008297005361	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1008297005362	transmembrane helices; other site
1008297005363	disulfide bond formation protein B; Provisional; Region: PRK01749
1008297005364	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1008297005365	GnsA/GnsB family; Region: GnsAB; pfam08178
1008297005366	hypothetical protein; Provisional; Region: PRK05170
1008297005367	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1008297005368	hypothetical protein; Provisional; Region: PRK10691
1008297005369	YcgL domain; Region: YcgL; cl01189
1008297005370	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1008297005371	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1008297005372	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1008297005373	cell division inhibitor MinD; Provisional; Region: PRK10818
1008297005374	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1008297005375	Switch I; other site
1008297005376	Switch II; other site
1008297005377	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1008297005378	ribonuclease D; Provisional; Region: PRK10829
1008297005379	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1008297005380	catalytic site [active]
1008297005381	putative active site [active]
1008297005382	putative substrate binding site [chemical binding]; other site
1008297005383	HRDC domain; Region: HRDC; cl02578
1008297005384	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1008297005385	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1008297005386	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1008297005387	acyl-activating enzyme (AAE) consensus motif; other site
1008297005388	putative AMP binding site [chemical binding]; other site
1008297005389	putative active site [active]
1008297005390	putative CoA binding site [chemical binding]; other site
1008297005391	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
1008297005392	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1008297005393	Glycoprotease family; Region: Peptidase_M22; pfam00814
1008297005394	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1008297005395	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1008297005396	DEAD_2; Region: DEAD_2; pfam06733
1008297005397	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1008297005398	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1008297005399	homotrimer interaction site [polypeptide binding]; other site
1008297005400	putative active site [active]
1008297005401	hypothetical protein; Provisional; Region: PRK05114
1008297005402	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1008297005403	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1008297005404	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
1008297005405	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1008297005406	putative active site [active]
1008297005407	putative CoA binding site [chemical binding]; other site
1008297005408	nudix motif; other site
1008297005409	metal binding site [ion binding]; metal-binding site
1008297005410	L-serine deaminase; Provisional; Region: PRK15023
1008297005411	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1008297005412	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1008297005413	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1008297005414	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297005415	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1008297005416	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1008297005417	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1008297005418	Transporter associated domain; Region: CorC_HlyC; smart01091
1008297005419	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1008297005420	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1008297005421	active pocket/dimerization site; other site
1008297005422	active site
1008297005423	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1008297005424	active site
1008297005425	phosphorylation site [posttranslational modification]
1008297005426	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1008297005427	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1008297005428	hypothetical protein; Provisional; Region: PRK02913
1008297005429	hypothetical protein; Provisional; Region: PRK11469
1008297005430	Domain of unknown function DUF; Region: DUF204; pfam02659
1008297005431	Domain of unknown function DUF; Region: DUF204; pfam02659
1008297005432	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1008297005433	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297005434	S-adenosylmethionine binding site [chemical binding]; other site
1008297005435	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1008297005436	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1008297005437	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1008297005438	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1008297005439	DNA-binding site [nucleotide binding]; DNA binding site
1008297005440	RNA-binding motif; other site
1008297005441	YebO-like protein; Region: YebO; pfam13974
1008297005442	PhoPQ regulatory protein; Provisional; Region: PRK10299
1008297005443	YobH-like protein; Region: YobH; pfam13996
1008297005444	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1008297005445	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1008297005446	dimerization interface [polypeptide binding]; other site
1008297005447	putative Zn2+ binding site [ion binding]; other site
1008297005448	putative DNA binding site [nucleotide binding]; other site
1008297005449	Bacterial transcriptional regulator; Region: IclR; pfam01614
1008297005450	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297005451	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1008297005452	putative substrate translocation pore; other site
1008297005453	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297005454	heat shock protein HtpX; Provisional; Region: PRK05457
1008297005455	carboxy-terminal protease; Provisional; Region: PRK11186
1008297005456	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1008297005457	protein binding site [polypeptide binding]; other site
1008297005458	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1008297005459	Catalytic dyad [active]
1008297005460	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1008297005461	ProP expression regulator; Provisional; Region: PRK04950
1008297005462	ProQ/FINO family; Region: ProQ; pfam04352
1008297005463	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1008297005464	GAF domain; Region: GAF_2; pfam13185
1008297005465	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1008297005466	Paraquat-inducible protein A; Region: PqiA; pfam04403
1008297005467	Paraquat-inducible protein A; Region: PqiA; pfam04403
1008297005468	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1008297005469	mce related protein; Region: MCE; pfam02470
1008297005470	mce related protein; Region: MCE; pfam02470
1008297005471	mce related protein; Region: MCE; pfam02470
1008297005472	mce related protein; Region: MCE; pfam02470
1008297005473	mce related protein; Region: MCE; pfam02470
1008297005474	mce related protein; Region: MCE; pfam02470
1008297005475	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1008297005476	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
1008297005477	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1008297005478	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1008297005479	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1008297005480	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
1008297005481	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1008297005482	type III secretion protein SopE2; Provisional; Region: PRK15280
1008297005483	SopE GEF domain; Region: SopE_GEF; pfam07487
1008297005484	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
1008297005485	putative transposase(pseudogene)
1008297005486	bacteriophage integrase (pseudogene)
1008297005487	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
1008297005488	ADP-ribose binding site [chemical binding]; other site
1008297005489	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1008297005490	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1008297005491	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
1008297005492	exonuclease VIII; Reviewed; Region: PRK09709
1008297005493	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1008297005494	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1008297005495	dimer interface [polypeptide binding]; other site
1008297005496	active site
1008297005497	Int/Topo IB signature motif; other site
1008297005498	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1008297005499	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1008297005500	hypothetical protein; Provisional; Region: PRK10301
1008297005501	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1008297005502	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1008297005503	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
1008297005504	exodeoxyribonuclease X; Provisional; Region: PRK07983
1008297005505	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1008297005506	active site
1008297005507	catalytic site [active]
1008297005508	substrate binding site [chemical binding]; other site
1008297005509	protease 2; Provisional; Region: PRK10115
1008297005510	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1008297005511	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1008297005512	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1008297005513	putative metal binding site [ion binding]; other site
1008297005514	hypothetical protein; Provisional; Region: PRK13680
1008297005515	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
1008297005516	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1008297005517	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1008297005518	ATP-grasp domain; Region: ATP-grasp; pfam02222
1008297005519	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1008297005520	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1008297005521	active site
1008297005522	intersubunit interface [polypeptide binding]; other site
1008297005523	catalytic residue [active]
1008297005524	phosphogluconate dehydratase; Validated; Region: PRK09054
1008297005525	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1008297005526	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1008297005527	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1008297005528	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1008297005529	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1008297005530	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1008297005531	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1008297005532	putative active site [active]
1008297005533	pyruvate kinase; Provisional; Region: PRK05826
1008297005534	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1008297005535	domain interfaces; other site
1008297005536	active site
1008297005537	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1008297005538	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1008297005539	putative acyl-acceptor binding pocket; other site
1008297005540	putative peptidase; Provisional; Region: PRK11649
1008297005541	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1008297005542	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1008297005543	Peptidase family M23; Region: Peptidase_M23; pfam01551
1008297005544	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1008297005545	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1008297005546	metal binding site [ion binding]; metal-binding site
1008297005547	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1008297005548	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1008297005549	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1008297005550	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1008297005551	ABC-ATPase subunit  interface; other site
1008297005552	dimer interface [polypeptide binding]; other site
1008297005553	putative PBP binding regions; other site
1008297005554	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1008297005555	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297005556	Walker A motif; other site
1008297005557	ATP binding site [chemical binding]; other site
1008297005558	Walker B motif; other site
1008297005559	arginine finger; other site
1008297005560	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1008297005561	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1008297005562	RuvA N terminal domain; Region: RuvA_N; pfam01330
1008297005563	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1008297005564	hypothetical protein (pseudogene)
1008297005565	hypothetical protein; Provisional; Region: PRK11470
1008297005566	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1008297005567	active site
1008297005568	putative DNA-binding cleft [nucleotide binding]; other site
1008297005569	dimer interface [polypeptide binding]; other site
1008297005570	hypothetical protein; Validated; Region: PRK00110
1008297005571	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1008297005572	nudix motif; other site
1008297005573	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1008297005574	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1008297005575	dimer interface [polypeptide binding]; other site
1008297005576	anticodon binding site; other site
1008297005577	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1008297005578	homodimer interface [polypeptide binding]; other site
1008297005579	motif 1; other site
1008297005580	active site
1008297005581	motif 2; other site
1008297005582	GAD domain; Region: GAD; pfam02938
1008297005583	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1008297005584	active site
1008297005585	motif 3; other site
1008297005586	Isochorismatase family; Region: Isochorismatase; pfam00857
1008297005587	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1008297005588	catalytic triad [active]
1008297005589	conserved cis-peptide bond; other site
1008297005590	hypothetical protein; Provisional; Region: PRK10302
1008297005591	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1008297005592	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297005593	S-adenosylmethionine binding site [chemical binding]; other site
1008297005594	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297005595	S-adenosylmethionine binding site [chemical binding]; other site
1008297005596	copper homeostasis protein CutC; Provisional; Region: PRK11572
1008297005597	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1008297005598	putative metal binding site [ion binding]; other site
1008297005599	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1008297005600	arginyl-tRNA synthetase; Region: argS; TIGR00456
1008297005601	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1008297005602	active site
1008297005603	HIGH motif; other site
1008297005604	KMSK motif region; other site
1008297005605	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1008297005606	tRNA binding surface [nucleotide binding]; other site
1008297005607	anticodon binding site; other site
1008297005608	penicillin-binding protein 2; Provisional; Region: PRK10795
1008297005609	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1008297005610	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1008297005611	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1008297005612	Flagellar protein FlhE; Region: FlhE; pfam06366
1008297005613	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1008297005614	FHIPEP family; Region: FHIPEP; pfam00771
1008297005615	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1008297005616	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1008297005617	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1008297005618	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1008297005619	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297005620	active site
1008297005621	phosphorylation site [posttranslational modification]
1008297005622	intermolecular recognition site; other site
1008297005623	dimerization interface [polypeptide binding]; other site
1008297005624	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1008297005625	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297005626	active site
1008297005627	phosphorylation site [posttranslational modification]
1008297005628	intermolecular recognition site; other site
1008297005629	dimerization interface [polypeptide binding]; other site
1008297005630	CheB methylesterase; Region: CheB_methylest; pfam01339
1008297005631	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1008297005632	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1008297005633	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297005634	S-adenosylmethionine binding site [chemical binding]; other site
1008297005635	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1008297005636	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1008297005637	dimer interface [polypeptide binding]; other site
1008297005638	ligand binding site [chemical binding]; other site
1008297005639	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297005640	dimerization interface [polypeptide binding]; other site
1008297005641	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1008297005642	dimer interface [polypeptide binding]; other site
1008297005643	putative CheW interface [polypeptide binding]; other site
1008297005644	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1008297005645	putative CheA interaction surface; other site
1008297005646	chemotaxis protein CheA; Provisional; Region: PRK10547
1008297005647	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1008297005648	putative binding surface; other site
1008297005649	active site
1008297005650	CheY binding; Region: CheY-binding; pfam09078
1008297005651	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1008297005652	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297005653	ATP binding site [chemical binding]; other site
1008297005654	Mg2+ binding site [ion binding]; other site
1008297005655	G-X-G motif; other site
1008297005656	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1008297005657	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1008297005658	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1008297005659	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1008297005660	ligand binding site [chemical binding]; other site
1008297005661	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1008297005662	flagellar motor protein MotA; Validated; Region: PRK09110
1008297005663	transcriptional activator FlhC; Provisional; Region: PRK12722
1008297005664	transcriptional activator FlhD; Provisional; Region: PRK02909
1008297005665	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1008297005666	Ligand Binding Site [chemical binding]; other site
1008297005667	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1008297005668	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1008297005669	active site
1008297005670	homotetramer interface [polypeptide binding]; other site
1008297005671	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
1008297005672	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1008297005673	DJ-1 family protein; Region: not_thiJ; TIGR01383
1008297005674	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1008297005675	conserved cys residue [active]
1008297005676	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1008297005677	Ferritin-like domain; Region: Ferritin; pfam00210
1008297005678	ferroxidase diiron center [ion binding]; other site
1008297005679	hypothetical protein; Provisional; Region: PRK09273
1008297005680	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
1008297005681	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
1008297005682	YecR-like lipoprotein; Region: YecR; pfam13992
1008297005683	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1008297005684	Ferritin-like domain; Region: Ferritin; pfam00210
1008297005685	ferroxidase diiron center [ion binding]; other site
1008297005686	probable metal-binding protein; Region: matur_matur; TIGR03853
1008297005687	tyrosine transporter TyrP; Provisional; Region: PRK15132
1008297005688	aromatic amino acid transport protein; Region: araaP; TIGR00837
1008297005689	hypothetical protein; Provisional; Region: PRK10396
1008297005690	yecA family protein; Region: ygfB_yecA; TIGR02292
1008297005691	SEC-C motif; Region: SEC-C; pfam02810
1008297005692	glucose-6-phosphate 1-dehydrogenase; Region: PLN02640
1008297005693	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
1008297005694	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
1008297005695	NlpC/P60 family; Region: NLPC_P60; cl17555
1008297005696	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1008297005697	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1008297005698	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1008297005699	GIY-YIG motif/motif A; other site
1008297005700	active site
1008297005701	catalytic site [active]
1008297005702	putative DNA binding site [nucleotide binding]; other site
1008297005703	metal binding site [ion binding]; metal-binding site
1008297005704	UvrB/uvrC motif; Region: UVR; pfam02151
1008297005705	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1008297005706	Helix-hairpin-helix motif; Region: HHH; pfam00633
1008297005707	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297005708	response regulator; Provisional; Region: PRK09483
1008297005709	active site
1008297005710	phosphorylation site [posttranslational modification]
1008297005711	intermolecular recognition site; other site
1008297005712	dimerization interface [polypeptide binding]; other site
1008297005713	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297005714	DNA binding residues [nucleotide binding]
1008297005715	dimerization interface [polypeptide binding]; other site
1008297005716	hypothetical protein; Provisional; Region: PRK10613
1008297005717	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1008297005718	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1008297005719	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297005720	DNA binding residues [nucleotide binding]
1008297005721	dimerization interface [polypeptide binding]; other site
1008297005722	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1008297005723	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1008297005724	Walker A/P-loop; other site
1008297005725	ATP binding site [chemical binding]; other site
1008297005726	Q-loop/lid; other site
1008297005727	ABC transporter signature motif; other site
1008297005728	Walker B; other site
1008297005729	D-loop; other site
1008297005730	H-loop/switch region; other site
1008297005731	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1008297005732	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1008297005733	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297005734	dimer interface [polypeptide binding]; other site
1008297005735	conserved gate region; other site
1008297005736	putative PBP binding loops; other site
1008297005737	ABC-ATPase subunit interface; other site
1008297005738	D-cysteine desulfhydrase; Validated; Region: PRK03910
1008297005739	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1008297005740	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297005741	catalytic residue [active]
1008297005742	cystine transporter subunit; Provisional; Region: PRK11260
1008297005743	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297005744	substrate binding pocket [chemical binding]; other site
1008297005745	membrane-bound complex binding site; other site
1008297005746	hinge residues; other site
1008297005747	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1008297005748	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1008297005749	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1008297005750	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1008297005751	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1008297005752	DNA binding residues [nucleotide binding]
1008297005753	Transposase IS200 like; Region: Y1_Tnp; cl00848
1008297005754	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
1008297005755	flagellin; Validated; Region: PRK08026
1008297005756	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1008297005757	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
1008297005758	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1008297005759	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1008297005760	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1008297005761	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1008297005762	flagellar protein FliS; Validated; Region: fliS; PRK05685
1008297005763	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
1008297005764	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1008297005765	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1008297005766	active site
1008297005767	Na/Ca binding site [ion binding]; other site
1008297005768	catalytic site [active]
1008297005769	lipoprotein; Provisional; Region: PRK10397
1008297005770	putative inner membrane protein; Provisional; Region: PRK11099
1008297005771	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1008297005772	CPxP  motif; other site
1008297005773	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1008297005774	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1008297005775	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1008297005776	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1008297005777	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1008297005778	FliG C-terminal domain; Region: FliG_C; pfam01706
1008297005779	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1008297005780	Flagellar assembly protein FliH; Region: FliH; pfam02108
1008297005781	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1008297005782	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1008297005783	Walker A motif/ATP binding site; other site
1008297005784	Walker B motif; other site
1008297005785	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1008297005786	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1008297005787	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
1008297005788	flagellar hook-length control protein; Provisional; Region: PRK10118
1008297005789	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1008297005790	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1008297005791	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1008297005792	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1008297005793	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1008297005794	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1008297005795	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1008297005796	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1008297005797	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1008297005798	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1008297005799	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297005800	DNA binding residues [nucleotide binding]
1008297005801	dimerization interface [polypeptide binding]; other site
1008297005802	hypothetical protein; Provisional; Region: PRK10708
1008297005803	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1008297005804	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1008297005805	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297005806	active site
1008297005807	motif I; other site
1008297005808	motif II; other site
1008297005809	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1008297005810	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1008297005811	metal binding site [ion binding]; metal-binding site
1008297005812	active site
1008297005813	I-site; other site
1008297005814	hypothetical protein; Provisional; Region: PRK10062
1008297005815	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1008297005816	EamA-like transporter family; Region: EamA; pfam00892
1008297005817	EamA-like transporter family; Region: EamA; pfam00892
1008297005818	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1008297005819	additional DNA contacts [nucleotide binding]; other site
1008297005820	mismatch recognition site; other site
1008297005821	active site
1008297005822	zinc binding site [ion binding]; other site
1008297005823	DNA intercalation site [nucleotide binding]; other site
1008297005824	DNA cytosine methylase; Provisional; Region: PRK10458
1008297005825	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1008297005826	cofactor binding site; other site
1008297005827	DNA binding site [nucleotide binding]
1008297005828	substrate interaction site [chemical binding]; other site
1008297005829	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1008297005830	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1008297005831	Zn2+ binding site [ion binding]; other site
1008297005832	Mg2+ binding site [ion binding]; other site
1008297005833	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1008297005834	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1008297005835	trimer interface [polypeptide binding]; other site
1008297005836	eyelet of channel; other site
1008297005837	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1008297005838	DNA-binding site [nucleotide binding]; DNA binding site
1008297005839	RNA-binding motif; other site
1008297005840	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1008297005841	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1008297005842	active site
1008297005843	DNA binding site [nucleotide binding]
1008297005844	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1008297005845	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1008297005846	Catalytic site [active]
1008297005847	type III secretion system protein; Provisional; Region: PRK15383
1008297005848	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
1008297005849	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1008297005850	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1008297005851	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
1008297005852	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
1008297005853	Baseplate J-like protein; Region: Baseplate_J; cl01294
1008297005854	Phage protein GP46; Region: GP46; pfam07409
1008297005855	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; pfam06890
1008297005856	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
1008297005857	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1008297005858	Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228
1008297005859	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
1008297005860	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1008297005861	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1008297005862	Phage tail tube protein; Region: Tail_tube; pfam10618
1008297005863	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
1008297005864	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
1008297005865	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
1008297005866	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
1008297005867	oligomerization interface [polypeptide binding]; other site
1008297005868	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
1008297005869	Phage capsid family; Region: Phage_capsid; pfam05065
1008297005870	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
1008297005871	Phage-related protein [Function unknown]; Region: COG4695
1008297005872	Phage portal protein; Region: Phage_portal; pfam04860
1008297005873	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
1008297005874	Phage terminase, small subunit; Region: Terminase_4; pfam05119
1008297005875	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
1008297005876	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1008297005877	active site
1008297005878	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1008297005879	Predicted chitinase [General function prediction only]; Region: COG3179
1008297005880	catalytic residue [active]
1008297005881	Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106
1008297005882	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1008297005883	KilA-N domain; Region: KilA-N; pfam04383
1008297005884	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
1008297005885	Helix-turn-helix domain; Region: HTH_36; pfam13730
1008297005886	Ash protein family; Region: Phage_ASH; pfam10554
1008297005887	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1008297005888	Predicted transcriptional regulator [Transcription]; Region: COG2932
1008297005889	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1008297005890	non-specific DNA binding site [nucleotide binding]; other site
1008297005891	salt bridge; other site
1008297005892	sequence-specific DNA binding site [nucleotide binding]; other site
1008297005893	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1008297005894	Catalytic site [active]
1008297005895	Uncharacterized conserved protein (DUF2303); Region: DUF2303; pfam10065
1008297005896	HD domain; Region: HD_3; cl17350
1008297005897	Protein of unknown function DUF262; Region: DUF262; pfam03235
1008297005898	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1008297005899	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1008297005900	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1008297005901	active site
1008297005902	catalytic site [active]
1008297005903	substrate binding site [chemical binding]; other site
1008297005904	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1008297005905	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1008297005906	dimer interface [polypeptide binding]; other site
1008297005907	active site
1008297005908	Int/Topo IB signature motif; other site
1008297005909	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1008297005910	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1008297005911	putative protease; Region: PHA00666
1008297005912	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
1008297005913	Integrase; Region: Integrase_1; pfam12835
1008297005914	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1008297005915	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1008297005916	Sel1 repeat; Region: Sel1; pfam08238
1008297005917	Sel1-like repeats; Region: SEL1; smart00671
1008297005918	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
1008297005919	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cl00723
1008297005920	AMP nucleosidase; Provisional; Region: PRK08292
1008297005921	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1008297005922	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1008297005923	MATE family multidrug exporter; Provisional; Region: PRK10189
1008297005924	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1008297005925	L,D-transpeptidase; Provisional; Region: PRK10190
1008297005926	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1008297005927	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1008297005928	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1008297005929	putative dimer interface [polypeptide binding]; other site
1008297005930	active site pocket [active]
1008297005931	putative cataytic base [active]
1008297005932	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1008297005933	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1008297005934	homotrimer interface [polypeptide binding]; other site
1008297005935	Walker A motif; other site
1008297005936	GTP binding site [chemical binding]; other site
1008297005937	Walker B motif; other site
1008297005938	cobyric acid synthase; Provisional; Region: PRK00784
1008297005939	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1008297005940	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1008297005941	catalytic triad [active]
1008297005942	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
1008297005943	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1008297005944	Walker A/P-loop; other site
1008297005945	ATP binding site [chemical binding]; other site
1008297005946	Q-loop/lid; other site
1008297005947	ABC transporter signature motif; other site
1008297005948	Walker B; other site
1008297005949	D-loop; other site
1008297005950	H-loop/switch region; other site
1008297005951	cobalt transport protein CbiQ; Provisional; Region: PRK15485
1008297005952	cobalt transport protein CbiN; Provisional; Region: PRK02898
1008297005953	cobalt transport protein CbiM; Validated; Region: PRK08319
1008297005954	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
1008297005955	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1008297005956	active site
1008297005957	SAM binding site [chemical binding]; other site
1008297005958	homodimer interface [polypeptide binding]; other site
1008297005959	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
1008297005960	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
1008297005961	active site
1008297005962	C-terminal domain interface [polypeptide binding]; other site
1008297005963	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
1008297005964	active site
1008297005965	N-terminal domain interface [polypeptide binding]; other site
1008297005966	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1008297005967	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
1008297005968	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1008297005969	active site
1008297005970	SAM binding site [chemical binding]; other site
1008297005971	homodimer interface [polypeptide binding]; other site
1008297005972	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1008297005973	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1008297005974	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1008297005975	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1008297005976	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1008297005977	active site
1008297005978	SAM binding site [chemical binding]; other site
1008297005979	homodimer interface [polypeptide binding]; other site
1008297005980	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
1008297005981	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297005982	S-adenosylmethionine binding site [chemical binding]; other site
1008297005983	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1008297005984	putative homodimer interface [polypeptide binding]; other site
1008297005985	active site
1008297005986	SAM binding site [chemical binding]; other site
1008297005987	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1008297005988	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
1008297005989	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1008297005990	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
1008297005991	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1008297005992	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1008297005993	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1008297005994	catalytic triad [active]
1008297005995	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
1008297005996	Sensory domain found in PocR; Region: PocR; pfam10114
1008297005997	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297005998	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1008297005999	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297006000	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1008297006001	amphipathic channel; other site
1008297006002	Asn-Pro-Ala signature motifs; other site
1008297006003	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1008297006004	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1008297006005	Hexamer interface [polypeptide binding]; other site
1008297006006	Putative hexagonal pore residue; other site
1008297006007	propanediol utilization protein PduB; Provisional; Region: PRK15415
1008297006008	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
1008297006009	putative hexamer interface [polypeptide binding]; other site
1008297006010	putative hexagonal pore; other site
1008297006011	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
1008297006012	putative hexamer interface [polypeptide binding]; other site
1008297006013	putative hexagonal pore; other site
1008297006014	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
1008297006015	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
1008297006016	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
1008297006017	alpha-beta subunit interface [polypeptide binding]; other site
1008297006018	alpha-gamma subunit interface [polypeptide binding]; other site
1008297006019	active site
1008297006020	substrate and K+ binding site; other site
1008297006021	K+ binding site [ion binding]; other site
1008297006022	cobalamin binding site [chemical binding]; other site
1008297006023	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
1008297006024	propanediol dehydratase small subunit; Provisional; Region: pduE; PRK15443
1008297006025	Cell division protein FtsA; Region: FtsA; cl17206
1008297006026	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
1008297006027	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
1008297006028	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1008297006029	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1008297006030	Hexamer interface [polypeptide binding]; other site
1008297006031	Putative hexagonal pore residue; other site
1008297006032	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1008297006033	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
1008297006034	putative hexamer interface [polypeptide binding]; other site
1008297006035	putative hexagonal pore; other site
1008297006036	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
1008297006037	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1008297006038	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1008297006039	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
1008297006040	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1008297006041	Hexamer/Pentamer interface [polypeptide binding]; other site
1008297006042	central pore; other site
1008297006043	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
1008297006044	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
1008297006045	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1008297006046	putative catalytic cysteine [active]
1008297006047	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1008297006048	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
1008297006049	putative active site [active]
1008297006050	metal binding site [ion binding]; metal-binding site
1008297006051	propanediol utilization ferredoxin
1008297006052	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
1008297006053	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1008297006054	putative hexamer interface [polypeptide binding]; other site
1008297006055	putative hexagonal pore; other site
1008297006056	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1008297006057	putative hexamer interface [polypeptide binding]; other site
1008297006058	putative hexagonal pore; other site
1008297006059	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1008297006060	putative hexamer interface [polypeptide binding]; other site
1008297006061	putative hexagonal pore; other site
1008297006062	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
1008297006063	G3 box; other site
1008297006064	Switch II region; other site
1008297006065	GTP/Mg2+ binding site [chemical binding]; other site
1008297006066	G4 box; other site
1008297006067	G5 box; other site
1008297006068	propionate kinase; Reviewed; Region: PRK12397
1008297006069	propionate/acetate kinase; Provisional; Region: PRK12379
1008297006070	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
1008297006071	hypothetical protein; Provisional; Region: PRK05423
1008297006072	Predicted membrane protein [Function unknown]; Region: COG1289
1008297006073	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1008297006074	DNA gyrase inhibitor; Provisional; Region: PRK10016
1008297006075	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1008297006076	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1008297006077	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1008297006078	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
1008297006079	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
1008297006080	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1008297006081	4Fe-4S binding domain; Region: Fer4; cl02805
1008297006082	thiosulfate reductase PhsA; Provisional; Region: PRK15488
1008297006083	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1008297006084	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
1008297006085	putative [Fe4-S4] binding site [ion binding]; other site
1008297006086	putative molybdopterin cofactor binding site [chemical binding]; other site
1008297006087	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297006088	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
1008297006089	putative molybdopterin cofactor binding site; other site
1008297006090	E3 ubiquitin-protein ligase SopA; Provisional; Region: PRK15377
1008297006091	SopA-like central domain; Region: SopA; pfam13981
1008297006092	SopA-like catalytic domain; Region: SopA_C; pfam13979
1008297006093	exonuclease I; Provisional; Region: sbcB; PRK11779
1008297006094	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1008297006095	active site
1008297006096	catalytic site [active]
1008297006097	substrate binding site [chemical binding]; other site
1008297006098	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1008297006099	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1008297006100	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297006101	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1008297006102	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297006103	dimerization interface [polypeptide binding]; other site
1008297006104	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1008297006105	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1008297006106	putative NAD(P) binding site [chemical binding]; other site
1008297006107	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1008297006108	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1008297006109	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1008297006110	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1008297006111	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1008297006112	NAD binding site [chemical binding]; other site
1008297006113	dimerization interface [polypeptide binding]; other site
1008297006114	product binding site; other site
1008297006115	substrate binding site [chemical binding]; other site
1008297006116	zinc binding site [ion binding]; other site
1008297006117	catalytic residues [active]
1008297006118	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1008297006119	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297006120	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297006121	homodimer interface [polypeptide binding]; other site
1008297006122	catalytic residue [active]
1008297006123	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1008297006124	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297006125	active site
1008297006126	motif I; other site
1008297006127	motif II; other site
1008297006128	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1008297006129	putative active site pocket [active]
1008297006130	4-fold oligomerization interface [polypeptide binding]; other site
1008297006131	metal binding residues [ion binding]; metal-binding site
1008297006132	3-fold/trimer interface [polypeptide binding]; other site
1008297006133	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1008297006134	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1008297006135	putative active site [active]
1008297006136	oxyanion strand; other site
1008297006137	catalytic triad [active]
1008297006138	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1008297006139	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1008297006140	catalytic residues [active]
1008297006141	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1008297006142	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1008297006143	substrate binding site [chemical binding]; other site
1008297006144	glutamase interaction surface [polypeptide binding]; other site
1008297006145	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1008297006146	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1008297006147	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1008297006148	metal binding site [ion binding]; metal-binding site
1008297006149	chain length determinant protein WzzB; Provisional; Region: PRK15471
1008297006150	Chain length determinant protein; Region: Wzz; pfam02706
1008297006151	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1008297006152	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1008297006153	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1008297006154	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1008297006155	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1008297006156	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1008297006157	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1008297006158	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1008297006159	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
1008297006160	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1008297006161	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1008297006162	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1008297006163	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
1008297006164	active site
1008297006165	substrate binding site [chemical binding]; other site
1008297006166	metal binding site [ion binding]; metal-binding site
1008297006167	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1008297006168	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1008297006169	Substrate binding site; other site
1008297006170	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1008297006171	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1008297006172	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1008297006173	active site
1008297006174	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1008297006175	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1008297006176	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1008297006177	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1008297006178	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1008297006179	active site
1008297006180	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
1008297006181	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1008297006182	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1008297006183	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1008297006184	NAD(P) binding site [chemical binding]; other site
1008297006185	active site
1008297006186	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1008297006187	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1008297006188	inhibitor-cofactor binding pocket; inhibition site
1008297006189	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297006190	catalytic residue [active]
1008297006191	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
1008297006192	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
1008297006193	NAD binding site [chemical binding]; other site
1008297006194	homotetramer interface [polypeptide binding]; other site
1008297006195	homodimer interface [polypeptide binding]; other site
1008297006196	substrate binding site [chemical binding]; other site
1008297006197	active site
1008297006198	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1008297006199	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1008297006200	substrate binding site; other site
1008297006201	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
1008297006202	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1008297006203	catalytic loop [active]
1008297006204	iron binding site [ion binding]; other site
1008297006205	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1008297006206	FAD binding pocket [chemical binding]; other site
1008297006207	FAD binding motif [chemical binding]; other site
1008297006208	phosphate binding motif [ion binding]; other site
1008297006209	beta-alpha-beta structure motif; other site
1008297006210	NAD binding pocket [chemical binding]; other site
1008297006211	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
1008297006212	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1008297006213	substrate binding site; other site
1008297006214	tetramer interface; other site
1008297006215	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
1008297006216	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1008297006217	NADP binding site [chemical binding]; other site
1008297006218	active site
1008297006219	putative substrate binding site [chemical binding]; other site
1008297006220	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
1008297006221	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1008297006222	NAD binding site [chemical binding]; other site
1008297006223	substrate binding site [chemical binding]; other site
1008297006224	homodimer interface [polypeptide binding]; other site
1008297006225	active site
1008297006226	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1008297006227	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1008297006228	active site
1008297006229	tetramer interface; other site
1008297006230	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
1008297006231	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
1008297006232	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1008297006233	putative ADP-binding pocket [chemical binding]; other site
1008297006234	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
1008297006235	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
1008297006236	colanic acid exporter; Provisional; Region: PRK10459
1008297006237	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1008297006238	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
1008297006239	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
1008297006240	phosphomannomutase CpsG; Provisional; Region: PRK15414
1008297006241	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1008297006242	active site
1008297006243	substrate binding site [chemical binding]; other site
1008297006244	metal binding site [ion binding]; metal-binding site
1008297006245	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
1008297006246	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1008297006247	Substrate binding site; other site
1008297006248	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1008297006249	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
1008297006250	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1008297006251	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1008297006252	active site
1008297006253	GDP-Mannose binding site [chemical binding]; other site
1008297006254	dimer interface [polypeptide binding]; other site
1008297006255	modified nudix motif
1008297006256	metal binding site [ion binding]; metal-binding site
1008297006257	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1008297006258	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1008297006259	NADP binding site [chemical binding]; other site
1008297006260	active site
1008297006261	putative substrate binding site [chemical binding]; other site
1008297006262	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1008297006263	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1008297006264	NADP-binding site; other site
1008297006265	homotetramer interface [polypeptide binding]; other site
1008297006266	substrate binding site [chemical binding]; other site
1008297006267	homodimer interface [polypeptide binding]; other site
1008297006268	active site
1008297006269	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
1008297006270	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1008297006271	putative trimer interface [polypeptide binding]; other site
1008297006272	putative active site [active]
1008297006273	putative substrate binding site [chemical binding]; other site
1008297006274	putative CoA binding site [chemical binding]; other site
1008297006275	putative glycosyl transferase; Provisional; Region: PRK10063
1008297006276	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1008297006277	metal-binding site
1008297006278	putative colanic acid biosynthesis protein; Provisional; Region: wcaD; cl08075
1008297006279	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
1008297006280	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1008297006281	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1008297006282	putative acyl transferase; Provisional; Region: PRK10191
1008297006283	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1008297006284	trimer interface [polypeptide binding]; other site
1008297006285	active site
1008297006286	substrate binding site [chemical binding]; other site
1008297006287	CoA binding site [chemical binding]; other site
1008297006288	putative glycosyl transferase; Provisional; Region: PRK10018
1008297006289	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1008297006290	active site
1008297006291	tyrosine kinase; Provisional; Region: PRK11519
1008297006292	Chain length determinant protein; Region: Wzz; pfam02706
1008297006293	Chain length determinant protein; Region: Wzz; cl15801
1008297006294	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1008297006295	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1008297006296	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1008297006297	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1008297006298	active site
1008297006299	polysaccharide export protein Wza; Provisional; Region: PRK15078
1008297006300	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1008297006301	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1008297006302	FOG: CBS domain [General function prediction only]; Region: COG0517
1008297006303	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1008297006304	Transporter associated domain; Region: CorC_HlyC; smart01091
1008297006305	putative assembly protein; Provisional; Region: PRK10833
1008297006306	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1008297006307	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1008297006308	trimer interface [polypeptide binding]; other site
1008297006309	active site
1008297006310	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1008297006311	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1008297006312	ATP-binding site [chemical binding]; other site
1008297006313	Sugar specificity; other site
1008297006314	Pyrimidine base specificity; other site
1008297006315	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
1008297006316	PAS domain S-box; Region: sensory_box; TIGR00229
1008297006317	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1008297006318	putative active site [active]
1008297006319	heme pocket [chemical binding]; other site
1008297006320	PAS domain S-box; Region: sensory_box; TIGR00229
1008297006321	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1008297006322	putative active site [active]
1008297006323	heme pocket [chemical binding]; other site
1008297006324	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1008297006325	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1008297006326	metal binding site [ion binding]; metal-binding site
1008297006327	active site
1008297006328	I-site; other site
1008297006329	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297006330	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1008297006331	AlkA N-terminal domain; Region: AlkA_N; pfam06029
1008297006332	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1008297006333	minor groove reading motif; other site
1008297006334	helix-hairpin-helix signature motif; other site
1008297006335	substrate binding pocket [chemical binding]; other site
1008297006336	active site
1008297006337	putative chaperone; Provisional; Region: PRK11678
1008297006338	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1008297006339	nucleotide binding site [chemical binding]; other site
1008297006340	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1008297006341	SBD interface [polypeptide binding]; other site
1008297006342	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1008297006343	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1008297006344	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297006345	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1008297006346	Protein export membrane protein; Region: SecD_SecF; cl14618
1008297006347	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1008297006348	putative transporter; Provisional; Region: PRK10504
1008297006349	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297006350	putative substrate translocation pore; other site
1008297006351	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1008297006352	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297006353	dimerization interface [polypeptide binding]; other site
1008297006354	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297006355	dimer interface [polypeptide binding]; other site
1008297006356	phosphorylation site [posttranslational modification]
1008297006357	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297006358	ATP binding site [chemical binding]; other site
1008297006359	Mg2+ binding site [ion binding]; other site
1008297006360	G-X-G motif; other site
1008297006361	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1008297006362	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297006363	active site
1008297006364	phosphorylation site [posttranslational modification]
1008297006365	intermolecular recognition site; other site
1008297006366	dimerization interface [polypeptide binding]; other site
1008297006367	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297006368	DNA binding site [nucleotide binding]
1008297006369	PcfJ-like protein; Region: PcfJ; pfam14284
1008297006370	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1008297006371	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
1008297006372	putative protease; Provisional; Region: PRK15452
1008297006373	Peptidase family U32; Region: Peptidase_U32; pfam01136
1008297006374	type III secretion system protein; Provisional; Region: PRK15384; cl14665
1008297006375	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
1008297006376	lipid kinase; Reviewed; Region: PRK13054
1008297006377	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1008297006378	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1008297006379	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1008297006380	putative active site; other site
1008297006381	catalytic residue [active]
1008297006382	nucleoside transporter; Region: 2A0110; TIGR00889
1008297006383	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297006384	putative substrate translocation pore; other site
1008297006385	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1008297006386	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297006387	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1008297006388	substrate binding site [chemical binding]; other site
1008297006389	ATP binding site [chemical binding]; other site
1008297006390	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1008297006391	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297006392	DNA-binding site [nucleotide binding]; DNA binding site
1008297006393	UTRA domain; Region: UTRA; pfam07702
1008297006394	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1008297006395	dimer interface [polypeptide binding]; other site
1008297006396	substrate binding site [chemical binding]; other site
1008297006397	ATP binding site [chemical binding]; other site
1008297006398	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1008297006399	substrate binding site [chemical binding]; other site
1008297006400	multimerization interface [polypeptide binding]; other site
1008297006401	ATP binding site [chemical binding]; other site
1008297006402	Predicted integral membrane protein [Function unknown]; Region: COG5455
1008297006403	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
1008297006404	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
1008297006405	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
1008297006406	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297006407	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297006408	PapC C-terminal domain; Region: PapC_C; pfam13953
1008297006409	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
1008297006410	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297006411	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297006412	fimbrial chaperone protein; Provisional; Region: PRK15220
1008297006413	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
1008297006414	antiporter inner membrane protein; Provisional; Region: PRK11670
1008297006415	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1008297006416	Walker A motif; other site
1008297006417	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1008297006418	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1008297006419	active site
1008297006420	HIGH motif; other site
1008297006421	KMSKS motif; other site
1008297006422	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1008297006423	tRNA binding surface [nucleotide binding]; other site
1008297006424	anticodon binding site; other site
1008297006425	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1008297006426	dimer interface [polypeptide binding]; other site
1008297006427	putative tRNA-binding site [nucleotide binding]; other site
1008297006428	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1008297006429	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1008297006430	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1008297006431	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1008297006432	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1008297006433	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1008297006434	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297006435	active site
1008297006436	phosphorylation site [posttranslational modification]
1008297006437	intermolecular recognition site; other site
1008297006438	dimerization interface [polypeptide binding]; other site
1008297006439	LytTr DNA-binding domain; Region: LytTR; pfam04397
1008297006440	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1008297006441	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1008297006442	GAF domain; Region: GAF; pfam01590
1008297006443	Histidine kinase; Region: His_kinase; pfam06580
1008297006444	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297006445	ATP binding site [chemical binding]; other site
1008297006446	Mg2+ binding site [ion binding]; other site
1008297006447	G-X-G motif; other site
1008297006448	transcriptional regulator MirA; Provisional; Region: PRK15043
1008297006449	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
1008297006450	DNA binding residues [nucleotide binding]
1008297006451	hypothetical protein; Provisional; Region: PRK13681
1008297006452	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
1008297006453	putative PBP binding loops; other site
1008297006454	ABC-ATPase subunit interface; other site
1008297006455	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1008297006456	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1008297006457	Walker A/P-loop; other site
1008297006458	ATP binding site [chemical binding]; other site
1008297006459	Q-loop/lid; other site
1008297006460	ABC transporter signature motif; other site
1008297006461	Walker B; other site
1008297006462	D-loop; other site
1008297006463	H-loop/switch region; other site
1008297006464	CBS domain; Region: CBS; pfam00571
1008297006465	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297006466	dimer interface [polypeptide binding]; other site
1008297006467	conserved gate region; other site
1008297006468	ABC-ATPase subunit interface; other site
1008297006469	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1008297006470	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1008297006471	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1008297006472	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1008297006473	D-lactate dehydrogenase; Provisional; Region: PRK11183
1008297006474	FAD binding domain; Region: FAD_binding_4; pfam01565
1008297006475	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1008297006476	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1008297006477	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1008297006478	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1008297006479	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1008297006480	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1008297006481	oxidoreductase; Provisional; Region: PRK12743
1008297006482	classical (c) SDRs; Region: SDR_c; cd05233
1008297006483	NAD(P) binding site [chemical binding]; other site
1008297006484	active site
1008297006485	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
1008297006486	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1008297006487	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1008297006488	FMN binding site [chemical binding]; other site
1008297006489	active site
1008297006490	catalytic residues [active]
1008297006491	substrate binding site [chemical binding]; other site
1008297006492	salicylate hydroxylase; Provisional; Region: PRK08163
1008297006493	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1008297006494	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
1008297006495	maleylacetoacetate isomerase; Region: maiA; TIGR01262
1008297006496	C-terminal domain interface [polypeptide binding]; other site
1008297006497	GSH binding site (G-site) [chemical binding]; other site
1008297006498	putative dimer interface [polypeptide binding]; other site
1008297006499	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
1008297006500	dimer interface [polypeptide binding]; other site
1008297006501	N-terminal domain interface [polypeptide binding]; other site
1008297006502	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
1008297006503	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1008297006504	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1008297006505	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
1008297006506	Cupin domain; Region: Cupin_2; pfam07883
1008297006507	Cupin domain; Region: Cupin_2; pfam07883
1008297006508	benzoate transport; Region: 2A0115; TIGR00895
1008297006509	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297006510	putative substrate translocation pore; other site
1008297006511	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1008297006512	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297006513	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297006514	dimerization interface [polypeptide binding]; other site
1008297006515	hypothetical protein; Provisional; Region: PRK01821
1008297006516	hypothetical protein; Provisional; Region: PRK10711
1008297006517	cytidine deaminase; Provisional; Region: PRK09027
1008297006518	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1008297006519	active site
1008297006520	catalytic motif [active]
1008297006521	Zn binding site [ion binding]; other site
1008297006522	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1008297006523	active site
1008297006524	catalytic motif [active]
1008297006525	Zn binding site [ion binding]; other site
1008297006526	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1008297006527	putative active site [active]
1008297006528	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
1008297006529	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1008297006530	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1008297006531	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297006532	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
1008297006533	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
1008297006534	homodimer interface [polypeptide binding]; other site
1008297006535	active site
1008297006536	FMN binding site [chemical binding]; other site
1008297006537	substrate binding site [chemical binding]; other site
1008297006538	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1008297006539	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1008297006540	TM-ABC transporter signature motif; other site
1008297006541	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1008297006542	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1008297006543	Walker A/P-loop; other site
1008297006544	ATP binding site [chemical binding]; other site
1008297006545	Q-loop/lid; other site
1008297006546	ABC transporter signature motif; other site
1008297006547	Walker B; other site
1008297006548	D-loop; other site
1008297006549	H-loop/switch region; other site
1008297006550	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1008297006551	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1008297006552	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1008297006553	ligand binding site [chemical binding]; other site
1008297006554	calcium binding site [ion binding]; other site
1008297006555	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1008297006556	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297006557	DNA binding site [nucleotide binding]
1008297006558	domain linker motif; other site
1008297006559	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1008297006560	dimerization interface (closed form) [polypeptide binding]; other site
1008297006561	ligand binding site [chemical binding]; other site
1008297006562	Predicted membrane protein [Function unknown]; Region: COG2311
1008297006563	hypothetical protein; Provisional; Region: PRK10835
1008297006564	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1008297006565	GTP cyclohydrolase I; Provisional; Region: PLN03044
1008297006566	active site
1008297006567	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1008297006568	S-formylglutathione hydrolase; Region: PLN02442
1008297006569	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1008297006570	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1008297006571	non-specific DNA binding site [nucleotide binding]; other site
1008297006572	salt bridge; other site
1008297006573	sequence-specific DNA binding site [nucleotide binding]; other site
1008297006574	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1008297006575	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1008297006576	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1008297006577	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1008297006578	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1008297006579	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297006580	motif II; other site
1008297006581	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1008297006582	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297006583	putative substrate translocation pore; other site
1008297006584	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
1008297006585	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1008297006586	N-terminal plug; other site
1008297006587	ligand-binding site [chemical binding]; other site
1008297006588	lysine transporter; Provisional; Region: PRK10836
1008297006589	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1008297006590	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297006591	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1008297006592	putative dimerization interface [polypeptide binding]; other site
1008297006593	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1008297006594	endonuclease IV; Provisional; Region: PRK01060
1008297006595	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1008297006596	AP (apurinic/apyrimidinic) site pocket; other site
1008297006597	DNA interaction; other site
1008297006598	Metal-binding active site; metal-binding site
1008297006599	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1008297006600	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1008297006601	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1008297006602	active site
1008297006603	P-loop; other site
1008297006604	phosphorylation site [posttranslational modification]
1008297006605	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1008297006606	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1008297006607	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1008297006608	putative substrate binding site [chemical binding]; other site
1008297006609	putative ATP binding site [chemical binding]; other site
1008297006610	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1008297006611	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297006612	active site
1008297006613	phosphorylation site [posttranslational modification]
1008297006614	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1008297006615	dimerization domain swap beta strand [polypeptide binding]; other site
1008297006616	regulatory protein interface [polypeptide binding]; other site
1008297006617	active site
1008297006618	regulatory phosphorylation site [posttranslational modification]; other site
1008297006619	sugar efflux transporter B; Provisional; Region: PRK15011
1008297006620	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297006621	putative substrate translocation pore; other site
1008297006622	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1008297006623	elongation factor P; Provisional; Region: PRK04542
1008297006624	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1008297006625	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1008297006626	RNA binding site [nucleotide binding]; other site
1008297006627	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1008297006628	RNA binding site [nucleotide binding]; other site
1008297006629	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1008297006630	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1008297006631	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1008297006632	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1008297006633	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1008297006634	active site
1008297006635	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1008297006636	NlpC/P60 family; Region: NLPC_P60; pfam00877
1008297006637	phage resistance protein; Provisional; Region: PRK10551
1008297006638	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1008297006639	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297006640	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1008297006641	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1008297006642	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1008297006643	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297006644	dimer interface [polypeptide binding]; other site
1008297006645	conserved gate region; other site
1008297006646	putative PBP binding loops; other site
1008297006647	ABC-ATPase subunit interface; other site
1008297006648	microcin C ABC transporter permease; Provisional; Region: PRK15021
1008297006649	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297006650	dimer interface [polypeptide binding]; other site
1008297006651	conserved gate region; other site
1008297006652	ABC-ATPase subunit interface; other site
1008297006653	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1008297006654	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297006655	Walker A/P-loop; other site
1008297006656	ATP binding site [chemical binding]; other site
1008297006657	Q-loop/lid; other site
1008297006658	ABC transporter signature motif; other site
1008297006659	Walker B; other site
1008297006660	D-loop; other site
1008297006661	H-loop/switch region; other site
1008297006662	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1008297006663	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297006664	Walker A/P-loop; other site
1008297006665	ATP binding site [chemical binding]; other site
1008297006666	Q-loop/lid; other site
1008297006667	ABC transporter signature motif; other site
1008297006668	Walker B; other site
1008297006669	D-loop; other site
1008297006670	H-loop/switch region; other site
1008297006671	hypothetical protein; Provisional; Region: PRK11835
1008297006672	bicyclomycin resistance protein
1008297006673	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1008297006674	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1008297006675	RNA binding surface [nucleotide binding]; other site
1008297006676	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1008297006677	active site
1008297006678	uracil binding [chemical binding]; other site
1008297006679	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1008297006680	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1008297006681	ATP binding site [chemical binding]; other site
1008297006682	putative Mg++ binding site [ion binding]; other site
1008297006683	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297006684	nucleotide binding region [chemical binding]; other site
1008297006685	ATP-binding site [chemical binding]; other site
1008297006686	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1008297006687	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1008297006688	5S rRNA interface [nucleotide binding]; other site
1008297006689	CTC domain interface [polypeptide binding]; other site
1008297006690	L16 interface [polypeptide binding]; other site
1008297006691	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1008297006692	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1008297006693	hypothetical protein; Provisional; Region: PRK13689
1008297006694	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1008297006695	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1008297006696	Sulfatase; Region: Sulfatase; cl17466
1008297006697	DinI-like family; Region: DinI; cl11630
1008297006698	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1008297006699	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1008297006700	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1008297006701	Phage T4 tail fibre; Region: Phage_T4_gp36; pfam03903
1008297006702	Phage head maturation protease [General function prediction only]; Region: COG3740
1008297006703	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1008297006704	Phage-related protein [Function unknown]; Region: COG4695; cl01923
1008297006705	Predicted P-loop ATPase [General function prediction only]; Region: COG4928
1008297006706	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
1008297006707	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1008297006708	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
1008297006709	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
1008297006710	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
1008297006711	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1008297006712	Leucine-rich repeats; other site
1008297006713	Substrate binding site [chemical binding]; other site
1008297006714	Putative bacteriophage tail fibre protein (pseudogene)
1008297006715	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
1008297006716	transcriptional regulator NarP; Provisional; Region: PRK10403
1008297006717	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297006718	active site
1008297006719	phosphorylation site [posttranslational modification]
1008297006720	intermolecular recognition site; other site
1008297006721	dimerization interface [polypeptide binding]; other site
1008297006722	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297006723	DNA binding residues [nucleotide binding]
1008297006724	dimerization interface [polypeptide binding]; other site
1008297006725	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1008297006726	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1008297006727	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1008297006728	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1008297006729	catalytic residues [active]
1008297006730	central insert; other site
1008297006731	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1008297006732	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1008297006733	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1008297006734	heme exporter protein CcmC; Region: ccmC; TIGR01191
1008297006735	heme exporter protein CcmB; Region: ccmB; TIGR01190
1008297006736	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297006737	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1008297006738	Walker A/P-loop; other site
1008297006739	ATP binding site [chemical binding]; other site
1008297006740	Q-loop/lid; other site
1008297006741	ABC transporter signature motif; other site
1008297006742	Walker B; other site
1008297006743	D-loop; other site
1008297006744	H-loop/switch region; other site
1008297006745	cytochrome c-type protein NapC; Provisional; Region: PRK10617
1008297006746	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1008297006747	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
1008297006748	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1008297006749	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1008297006750	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1008297006751	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1008297006752	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1008297006753	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1008297006754	[4Fe-4S] binding site [ion binding]; other site
1008297006755	molybdopterin cofactor binding site; other site
1008297006756	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1008297006757	molybdopterin cofactor binding site; other site
1008297006758	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
1008297006759	4Fe-4S binding domain; Region: Fer4; cl02805
1008297006760	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1008297006761	secondary substrate binding site; other site
1008297006762	primary substrate binding site; other site
1008297006763	inhibition loop; other site
1008297006764	dimerization interface [polypeptide binding]; other site
1008297006765	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1008297006766	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1008297006767	Walker A/P-loop; other site
1008297006768	ATP binding site [chemical binding]; other site
1008297006769	Q-loop/lid; other site
1008297006770	ABC transporter signature motif; other site
1008297006771	Walker B; other site
1008297006772	D-loop; other site
1008297006773	H-loop/switch region; other site
1008297006774	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1008297006775	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1008297006776	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1008297006777	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297006778	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1008297006779	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1008297006780	DNA binding site [nucleotide binding]
1008297006781	active site
1008297006782	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1008297006783	ApbE family; Region: ApbE; pfam02424
1008297006784	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1008297006785	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1008297006786	trimer interface [polypeptide binding]; other site
1008297006787	eyelet of channel; other site
1008297006788	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1008297006789	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297006790	ATP binding site [chemical binding]; other site
1008297006791	G-X-G motif; other site
1008297006792	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1008297006793	putative binding surface; other site
1008297006794	active site
1008297006795	transcriptional regulator RcsB; Provisional; Region: PRK10840
1008297006796	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297006797	active site
1008297006798	phosphorylation site [posttranslational modification]
1008297006799	intermolecular recognition site; other site
1008297006800	dimerization interface [polypeptide binding]; other site
1008297006801	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297006802	DNA binding residues [nucleotide binding]
1008297006803	dimerization interface [polypeptide binding]; other site
1008297006804	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1008297006805	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297006806	dimer interface [polypeptide binding]; other site
1008297006807	phosphorylation site [posttranslational modification]
1008297006808	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297006809	ATP binding site [chemical binding]; other site
1008297006810	Mg2+ binding site [ion binding]; other site
1008297006811	G-X-G motif; other site
1008297006812	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1008297006813	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297006814	active site
1008297006815	phosphorylation site [posttranslational modification]
1008297006816	intermolecular recognition site; other site
1008297006817	dimerization interface [polypeptide binding]; other site
1008297006818	DNA gyrase subunit A; Validated; Region: PRK05560
1008297006819	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1008297006820	CAP-like domain; other site
1008297006821	active site
1008297006822	primary dimer interface [polypeptide binding]; other site
1008297006823	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1008297006824	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1008297006825	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1008297006826	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1008297006827	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1008297006828	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1008297006829	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1008297006830	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1008297006831	active site pocket [active]
1008297006832	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1008297006833	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297006834	putative substrate translocation pore; other site
1008297006835	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1008297006836	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297006837	DNA-binding site [nucleotide binding]; DNA binding site
1008297006838	FCD domain; Region: FCD; pfam07729
1008297006839	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1008297006840	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297006841	S-adenosylmethionine binding site [chemical binding]; other site
1008297006842	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1008297006843	ATP cone domain; Region: ATP-cone; pfam03477
1008297006844	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1008297006845	active site
1008297006846	dimer interface [polypeptide binding]; other site
1008297006847	catalytic residues [active]
1008297006848	effector binding site; other site
1008297006849	R2 peptide binding site; other site
1008297006850	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1008297006851	dimer interface [polypeptide binding]; other site
1008297006852	putative radical transfer pathway; other site
1008297006853	diiron center [ion binding]; other site
1008297006854	tyrosyl radical; other site
1008297006855	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1008297006856	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1008297006857	catalytic loop [active]
1008297006858	iron binding site [ion binding]; other site
1008297006859	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1008297006860	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297006861	putative substrate translocation pore; other site
1008297006862	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
1008297006863	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297006864	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1008297006865	dimerization interface [polypeptide binding]; other site
1008297006866	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1008297006867	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1008297006868	active site
1008297006869	catalytic site [active]
1008297006870	metal binding site [ion binding]; metal-binding site
1008297006871	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1008297006872	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297006873	putative substrate translocation pore; other site
1008297006874	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1008297006875	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1008297006876	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1008297006877	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1008297006878	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1008297006879	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1008297006880	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1008297006881	Cysteine-rich domain; Region: CCG; pfam02754
1008297006882	Cysteine-rich domain; Region: CCG; pfam02754
1008297006883	deubiquitinase SseL; Provisional; Region: PRK14848
1008297006884	hypothetical protein; Provisional; Region: PRK03673
1008297006885	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
1008297006886	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297006887	D-galactonate transporter; Region: 2A0114; TIGR00893
1008297006888	putative substrate translocation pore; other site
1008297006889	L-rhamnonate dehydratase; Provisional; Region: PRK15440
1008297006890	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
1008297006891	putative active site pocket [active]
1008297006892	putative metal binding site [ion binding]; other site
1008297006893	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1008297006894	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1008297006895	Bacterial transcriptional regulator; Region: IclR; pfam01614
1008297006896	hypothetical protein; Provisional; Region: PRK03673
1008297006897	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1008297006898	putative MPT binding site; other site
1008297006899	Competence-damaged protein; Region: CinA; cl00666
1008297006900	YfaZ precursor; Region: YfaZ; pfam07437
1008297006901	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1008297006902	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1008297006903	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1008297006904	catalytic core [active]
1008297006905	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1008297006906	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1008297006907	inhibitor-cofactor binding pocket; inhibition site
1008297006908	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297006909	catalytic residue [active]
1008297006910	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1008297006911	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1008297006912	Ligand binding site; other site
1008297006913	Putative Catalytic site; other site
1008297006914	DXD motif; other site
1008297006915	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1008297006916	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1008297006917	active site
1008297006918	substrate binding site [chemical binding]; other site
1008297006919	cosubstrate binding site; other site
1008297006920	catalytic site [active]
1008297006921	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1008297006922	active site
1008297006923	hexamer interface [polypeptide binding]; other site
1008297006924	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1008297006925	NAD binding site [chemical binding]; other site
1008297006926	substrate binding site [chemical binding]; other site
1008297006927	active site
1008297006928	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1008297006929	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1008297006930	putative active site [active]
1008297006931	putative catalytic site [active]
1008297006932	putative Zn binding site [ion binding]; other site
1008297006933	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1008297006934	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1008297006935	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1008297006936	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1008297006937	signal transduction protein PmrD; Provisional; Region: PRK15450
1008297006938	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1008297006939	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1008297006940	acyl-activating enzyme (AAE) consensus motif; other site
1008297006941	putative AMP binding site [chemical binding]; other site
1008297006942	putative active site [active]
1008297006943	putative CoA binding site [chemical binding]; other site
1008297006944	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
1008297006945	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1008297006946	active site
1008297006947	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1008297006948	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1008297006949	substrate binding site [chemical binding]; other site
1008297006950	oxyanion hole (OAH) forming residues; other site
1008297006951	trimer interface [polypeptide binding]; other site
1008297006952	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1008297006953	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1008297006954	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1008297006955	dimer interface [polypeptide binding]; other site
1008297006956	tetramer interface [polypeptide binding]; other site
1008297006957	PYR/PP interface [polypeptide binding]; other site
1008297006958	TPP binding site [chemical binding]; other site
1008297006959	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1008297006960	TPP-binding site; other site
1008297006961	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1008297006962	isochorismate synthases; Region: isochor_syn; TIGR00543
1008297006963	hypothetical protein; Provisional; Region: PRK10404
1008297006964	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297006965	Coenzyme A binding pocket [chemical binding]; other site
1008297006966	ribonuclease BN; Region: true_RNase_BN; TIGR02649
1008297006967	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1008297006968	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1008297006969	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297006970	active site
1008297006971	phosphorylation site [posttranslational modification]
1008297006972	intermolecular recognition site; other site
1008297006973	dimerization interface [polypeptide binding]; other site
1008297006974	von Willebrand factor; Region: vWF_A; pfam12450
1008297006975	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
1008297006976	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
1008297006977	metal ion-dependent adhesion site (MIDAS); other site
1008297006978	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
1008297006979	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1008297006980	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1008297006981	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1008297006982	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1008297006983	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1008297006984	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1008297006985	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1008297006986	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1008297006987	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1008297006988	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1008297006989	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1008297006990	4Fe-4S binding domain; Region: Fer4; pfam00037
1008297006991	4Fe-4S binding domain; Region: Fer4; pfam00037
1008297006992	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1008297006993	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1008297006994	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1008297006995	catalytic loop [active]
1008297006996	iron binding site [ion binding]; other site
1008297006997	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1008297006998	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1008297006999	[4Fe-4S] binding site [ion binding]; other site
1008297007000	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1008297007001	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1008297007002	SLBB domain; Region: SLBB; pfam10531
1008297007003	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1008297007004	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1008297007005	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1008297007006	putative dimer interface [polypeptide binding]; other site
1008297007007	[2Fe-2S] cluster binding site [ion binding]; other site
1008297007008	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1008297007009	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1008297007010	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1008297007011	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1008297007012	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1008297007013	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1008297007014	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297007015	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1008297007016	putative dimerization interface [polypeptide binding]; other site
1008297007017	aminotransferase AlaT; Validated; Region: PRK09265
1008297007018	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297007019	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297007020	homodimer interface [polypeptide binding]; other site
1008297007021	catalytic residue [active]
1008297007022	5'-nucleotidase; Provisional; Region: PRK03826
1008297007023	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1008297007024	transmembrane helices; other site
1008297007025	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1008297007026	TrkA-C domain; Region: TrkA_C; pfam02080
1008297007027	TrkA-C domain; Region: TrkA_C; pfam02080
1008297007028	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1008297007029	putative phosphatase; Provisional; Region: PRK11587
1008297007030	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297007031	motif II; other site
1008297007032	hypothetical protein; Validated; Region: PRK05445
1008297007033	hypothetical protein; Provisional; Region: PRK01816
1008297007034	propionate/acetate kinase; Provisional; Region: PRK12379
1008297007035	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1008297007036	phosphate acetyltransferase; Reviewed; Region: PRK05632
1008297007037	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1008297007038	DRTGG domain; Region: DRTGG; pfam07085
1008297007039	phosphate acetyltransferase; Region: pta; TIGR00651
1008297007040	hypothetical protein; Provisional; Region: PRK11588
1008297007041	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1008297007042	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1008297007043	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1008297007044	PYR/PP interface [polypeptide binding]; other site
1008297007045	dimer interface [polypeptide binding]; other site
1008297007046	TPP binding site [chemical binding]; other site
1008297007047	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1008297007048	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1008297007049	TPP-binding site [chemical binding]; other site
1008297007050	dimer interface [polypeptide binding]; other site
1008297007051	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
1008297007052	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1008297007053	active site
1008297007054	P-loop; other site
1008297007055	phosphorylation site [posttranslational modification]
1008297007056	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297007057	active site
1008297007058	phosphorylation site [posttranslational modification]
1008297007059	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1008297007060	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297007061	DNA binding site [nucleotide binding]
1008297007062	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1008297007063	putative dimerization interface [polypeptide binding]; other site
1008297007064	putative ligand binding site [chemical binding]; other site
1008297007065	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1008297007066	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1008297007067	nudix motif; other site
1008297007068	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1008297007069	active site
1008297007070	metal binding site [ion binding]; metal-binding site
1008297007071	homotetramer interface [polypeptide binding]; other site
1008297007072	glutathione S-transferase; Provisional; Region: PRK15113
1008297007073	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1008297007074	C-terminal domain interface [polypeptide binding]; other site
1008297007075	GSH binding site (G-site) [chemical binding]; other site
1008297007076	dimer interface [polypeptide binding]; other site
1008297007077	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1008297007078	N-terminal domain interface [polypeptide binding]; other site
1008297007079	putative dimer interface [polypeptide binding]; other site
1008297007080	putative substrate binding pocket (H-site) [chemical binding]; other site
1008297007081	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1008297007082	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1008297007083	C-terminal domain interface [polypeptide binding]; other site
1008297007084	GSH binding site (G-site) [chemical binding]; other site
1008297007085	dimer interface [polypeptide binding]; other site
1008297007086	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1008297007087	N-terminal domain interface [polypeptide binding]; other site
1008297007088	putative dimer interface [polypeptide binding]; other site
1008297007089	active site
1008297007090	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1008297007091	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1008297007092	putative NAD(P) binding site [chemical binding]; other site
1008297007093	putative active site [active]
1008297007094	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1008297007095	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1008297007096	Walker A/P-loop; other site
1008297007097	ATP binding site [chemical binding]; other site
1008297007098	Q-loop/lid; other site
1008297007099	ABC transporter signature motif; other site
1008297007100	Walker B; other site
1008297007101	D-loop; other site
1008297007102	H-loop/switch region; other site
1008297007103	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1008297007104	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297007105	dimer interface [polypeptide binding]; other site
1008297007106	conserved gate region; other site
1008297007107	putative PBP binding loops; other site
1008297007108	ABC-ATPase subunit interface; other site
1008297007109	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1008297007110	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297007111	dimer interface [polypeptide binding]; other site
1008297007112	conserved gate region; other site
1008297007113	putative PBP binding loops; other site
1008297007114	ABC-ATPase subunit interface; other site
1008297007115	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1008297007116	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297007117	substrate binding pocket [chemical binding]; other site
1008297007118	membrane-bound complex binding site; other site
1008297007119	hinge residues; other site
1008297007120	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1008297007121	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297007122	substrate binding pocket [chemical binding]; other site
1008297007123	membrane-bound complex binding site; other site
1008297007124	hinge residues; other site
1008297007125	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1008297007126	Flavoprotein; Region: Flavoprotein; pfam02441
1008297007127	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1008297007128	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
1008297007129	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
1008297007130	dimer interface [polypeptide binding]; other site
1008297007131	active site
1008297007132	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1008297007133	substrate binding site [chemical binding]; other site
1008297007134	catalytic residue [active]
1008297007135	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
1008297007136	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1008297007137	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1008297007138	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1008297007139	catalytic residue [active]
1008297007140	PAS fold; Region: PAS_4; pfam08448
1008297007141	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1008297007142	putative active site [active]
1008297007143	heme pocket [chemical binding]; other site
1008297007144	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1008297007145	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297007146	Walker A motif; other site
1008297007147	ATP binding site [chemical binding]; other site
1008297007148	Walker B motif; other site
1008297007149	arginine finger; other site
1008297007150	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1008297007151	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1008297007152	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1008297007153	active site
1008297007154	tetramer interface [polypeptide binding]; other site
1008297007155	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1008297007156	active site
1008297007157	colicin V production protein; Provisional; Region: PRK10845
1008297007158	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1008297007159	cell division protein DedD; Provisional; Region: PRK11633
1008297007160	Sporulation related domain; Region: SPOR; pfam05036
1008297007161	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1008297007162	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1008297007163	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1008297007164	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1008297007165	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1008297007166	hypothetical protein; Provisional; Region: PRK10847
1008297007167	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1008297007168	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
1008297007169	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1008297007170	dimerization interface 3.5A [polypeptide binding]; other site
1008297007171	active site
1008297007172	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1008297007173	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1008297007174	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1008297007175	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1008297007176	ligand binding site [chemical binding]; other site
1008297007177	NAD binding site [chemical binding]; other site
1008297007178	catalytic site [active]
1008297007179	homodimer interface [polypeptide binding]; other site
1008297007180	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1008297007181	putative transporter; Provisional; Region: PRK12382
1008297007182	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297007183	putative substrate translocation pore; other site
1008297007184	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1008297007185	non-specific DNA binding site [nucleotide binding]; other site
1008297007186	salt bridge; other site
1008297007187	sequence-specific DNA binding site [nucleotide binding]; other site
1008297007188	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1008297007189	CAAX protease self-immunity; Region: Abi; pfam02517
1008297007190	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1008297007191	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1008297007192	dimer interface [polypeptide binding]; other site
1008297007193	active site
1008297007194	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1008297007195	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1008297007196	YfcL protein; Region: YfcL; pfam08891
1008297007197	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
1008297007198	hypothetical protein; Provisional; Region: PRK10621
1008297007199	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1008297007200	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1008297007201	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1008297007202	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1008297007203	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1008297007204	Tetramer interface [polypeptide binding]; other site
1008297007205	active site
1008297007206	FMN-binding site [chemical binding]; other site
1008297007207	HemK family putative methylases; Region: hemK_fam; TIGR00536
1008297007208	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297007209	S-adenosylmethionine binding site [chemical binding]; other site
1008297007210	hypothetical protein; Provisional; Region: PRK04946
1008297007211	Smr domain; Region: Smr; pfam01713
1008297007212	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1008297007213	catalytic core [active]
1008297007214	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1008297007215	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1008297007216	substrate binding site [chemical binding]; other site
1008297007217	oxyanion hole (OAH) forming residues; other site
1008297007218	trimer interface [polypeptide binding]; other site
1008297007219	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1008297007220	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1008297007221	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1008297007222	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1008297007223	dimer interface [polypeptide binding]; other site
1008297007224	active site
1008297007225	Protein of unknown function (DUF406); Region: DUF406; cl11449
1008297007226	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1008297007227	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1008297007228	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1008297007229	outer membrane protease; Reviewed; Region: PRK10993
1008297007230	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1008297007231	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297007232	active site
1008297007233	phosphorylation site [posttranslational modification]
1008297007234	intermolecular recognition site; other site
1008297007235	dimerization interface [polypeptide binding]; other site
1008297007236	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1008297007237	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1008297007238	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
1008297007239	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1008297007240	dimerization interface [polypeptide binding]; other site
1008297007241	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297007242	dimer interface [polypeptide binding]; other site
1008297007243	phosphorylation site [posttranslational modification]
1008297007244	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297007245	ATP binding site [chemical binding]; other site
1008297007246	Mg2+ binding site [ion binding]; other site
1008297007247	G-X-G motif; other site
1008297007248	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1008297007249	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1008297007250	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1008297007251	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297007252	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297007253	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
1008297007254	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1008297007255	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1008297007256	putative acyl-acceptor binding pocket; other site
1008297007257	aminotransferase; Validated; Region: PRK08175
1008297007258	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297007259	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297007260	homodimer interface [polypeptide binding]; other site
1008297007261	catalytic residue [active]
1008297007262	glucokinase; Provisional; Region: glk; PRK00292
1008297007263	glucokinase, proteobacterial type; Region: glk; TIGR00749
1008297007264	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1008297007265	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1008297007266	Cl- selectivity filter; other site
1008297007267	Cl- binding residues [ion binding]; other site
1008297007268	pore gating glutamate residue; other site
1008297007269	dimer interface [polypeptide binding]; other site
1008297007270	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
1008297007271	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1008297007272	dimer interface [polypeptide binding]; other site
1008297007273	PYR/PP interface [polypeptide binding]; other site
1008297007274	TPP binding site [chemical binding]; other site
1008297007275	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1008297007276	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1008297007277	TPP-binding site [chemical binding]; other site
1008297007278	dimer interface [polypeptide binding]; other site
1008297007279	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1008297007280	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1008297007281	active site
1008297007282	catalytic tetrad [active]
1008297007283	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1008297007284	manganese transport protein MntH; Reviewed; Region: PRK00701
1008297007285	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1008297007286	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1008297007287	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1008297007288	Nucleoside recognition; Region: Gate; pfam07670
1008297007289	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1008297007290	MASE1; Region: MASE1; pfam05231
1008297007291	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1008297007292	diguanylate cyclase; Region: GGDEF; smart00267
1008297007293	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297007294	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1008297007295	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1008297007296	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1008297007297	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1008297007298	active site
1008297007299	HIGH motif; other site
1008297007300	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1008297007301	active site
1008297007302	KMSKS motif; other site
1008297007303	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297007304	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297007305	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297007306	dimerization interface [polypeptide binding]; other site
1008297007307	XapX domain; Region: XapX; TIGR03510
1008297007308	nucleoside transporter; Region: 2A0110; TIGR00889
1008297007309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297007310	putative substrate translocation pore; other site
1008297007311	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1008297007312	hypothetical protein; Provisional; Region: PRK11528
1008297007313	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297007314	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297007315	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1008297007316	putative dimerization interface [polypeptide binding]; other site
1008297007317	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1008297007318	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1008297007319	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1008297007320	DNA ligase
1008297007321	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
1008297007322	cell division protein ZipA; Provisional; Region: PRK03427
1008297007323	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1008297007324	FtsZ protein binding site [polypeptide binding]; other site
1008297007325	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1008297007326	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1008297007327	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1008297007328	dimer interface [polypeptide binding]; other site
1008297007329	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297007330	catalytic residue [active]
1008297007331	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1008297007332	dimerization domain swap beta strand [polypeptide binding]; other site
1008297007333	regulatory protein interface [polypeptide binding]; other site
1008297007334	active site
1008297007335	regulatory phosphorylation site [posttranslational modification]; other site
1008297007336	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1008297007337	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1008297007338	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1008297007339	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1008297007340	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1008297007341	HPr interaction site; other site
1008297007342	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1008297007343	active site
1008297007344	phosphorylation site [posttranslational modification]
1008297007345	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1008297007346	dimer interface [polypeptide binding]; other site
1008297007347	pyridoxamine kinase; Validated; Region: PRK05756
1008297007348	pyridoxal binding site [chemical binding]; other site
1008297007349	ATP binding site [chemical binding]; other site
1008297007350	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
1008297007351	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297007352	DNA-binding site [nucleotide binding]; DNA binding site
1008297007353	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297007354	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297007355	homodimer interface [polypeptide binding]; other site
1008297007356	catalytic residue [active]
1008297007357	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1008297007358	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1008297007359	catalytic triad [active]
1008297007360	hypothetical protein; Provisional; Region: PRK10318
1008297007361	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
1008297007362	Transglycosylase; Region: Transgly; cl17702
1008297007363	cysteine synthase B; Region: cysM; TIGR01138
1008297007364	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1008297007365	dimer interface [polypeptide binding]; other site
1008297007366	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297007367	catalytic residue [active]
1008297007368	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1008297007369	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1008297007370	Walker A/P-loop; other site
1008297007371	ATP binding site [chemical binding]; other site
1008297007372	Q-loop/lid; other site
1008297007373	ABC transporter signature motif; other site
1008297007374	Walker B; other site
1008297007375	D-loop; other site
1008297007376	H-loop/switch region; other site
1008297007377	TOBE-like domain; Region: TOBE_3; pfam12857
1008297007378	sulfate transport protein; Provisional; Region: cysT; CHL00187
1008297007379	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297007380	dimer interface [polypeptide binding]; other site
1008297007381	conserved gate region; other site
1008297007382	putative PBP binding loops; other site
1008297007383	ABC-ATPase subunit interface; other site
1008297007384	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1008297007385	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297007386	dimer interface [polypeptide binding]; other site
1008297007387	conserved gate region; other site
1008297007388	putative PBP binding loops; other site
1008297007389	ABC-ATPase subunit interface; other site
1008297007390	thiosulfate transporter subunit; Provisional; Region: PRK10852
1008297007391	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1008297007392	short chain dehydrogenase; Provisional; Region: PRK08226
1008297007393	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
1008297007394	NAD binding site [chemical binding]; other site
1008297007395	homotetramer interface [polypeptide binding]; other site
1008297007396	homodimer interface [polypeptide binding]; other site
1008297007397	active site
1008297007398	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1008297007399	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1008297007400	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1008297007401	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1008297007402	putative acetyltransferase; Provisional; Region: PRK03624
1008297007403	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297007404	Coenzyme A binding pocket [chemical binding]; other site
1008297007405	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1008297007406	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1008297007407	active site
1008297007408	metal binding site [ion binding]; metal-binding site
1008297007409	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1008297007410	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1008297007411	transcriptional regulator EutR; Provisional; Region: PRK10130
1008297007412	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297007413	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297007414	carboxysome structural protein EutK; Provisional; Region: PRK15466
1008297007415	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1008297007416	Hexamer interface [polypeptide binding]; other site
1008297007417	Hexagonal pore residue; other site
1008297007418	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1008297007419	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
1008297007420	putative hexamer interface [polypeptide binding]; other site
1008297007421	putative hexagonal pore; other site
1008297007422	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1008297007423	putative hexamer interface [polypeptide binding]; other site
1008297007424	putative hexagonal pore; other site
1008297007425	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1008297007426	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1008297007427	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1008297007428	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
1008297007429	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
1008297007430	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
1008297007431	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1008297007432	active site
1008297007433	metal binding site [ion binding]; metal-binding site
1008297007434	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
1008297007435	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1008297007436	nucleotide binding site [chemical binding]; other site
1008297007437	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1008297007438	putative catalytic cysteine [active]
1008297007439	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1008297007440	Hexamer/Pentamer interface [polypeptide binding]; other site
1008297007441	central pore; other site
1008297007442	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1008297007443	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1008297007444	Hexamer interface [polypeptide binding]; other site
1008297007445	Putative hexagonal pore residue; other site
1008297007446	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1008297007447	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
1008297007448	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1008297007449	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
1008297007450	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1008297007451	G1 box; other site
1008297007452	GTP/Mg2+ binding site [chemical binding]; other site
1008297007453	G2 box; other site
1008297007454	Switch I region; other site
1008297007455	G3 box; other site
1008297007456	Switch II region; other site
1008297007457	G4 box; other site
1008297007458	G5 box; other site
1008297007459	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1008297007460	putative hexamer interface [polypeptide binding]; other site
1008297007461	putative hexagonal pore; other site
1008297007462	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1008297007463	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1008297007464	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1008297007465	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1008297007466	putative NAD(P) binding site [chemical binding]; other site
1008297007467	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1008297007468	transaldolase-like protein; Provisional; Region: PTZ00411
1008297007469	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1008297007470	active site
1008297007471	dimer interface [polypeptide binding]; other site
1008297007472	catalytic residue [active]
1008297007473	transketolase; Reviewed; Region: PRK12753
1008297007474	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1008297007475	TPP-binding site [chemical binding]; other site
1008297007476	dimer interface [polypeptide binding]; other site
1008297007477	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1008297007478	PYR/PP interface [polypeptide binding]; other site
1008297007479	dimer interface [polypeptide binding]; other site
1008297007480	TPP binding site [chemical binding]; other site
1008297007481	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1008297007482	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1008297007483	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1008297007484	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1008297007485	dimer interface [polypeptide binding]; other site
1008297007486	ADP-ribose binding site [chemical binding]; other site
1008297007487	active site
1008297007488	nudix motif; other site
1008297007489	metal binding site [ion binding]; metal-binding site
1008297007490	putative periplasmic esterase; Provisional; Region: PRK03642
1008297007491	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1008297007492	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1008297007493	4Fe-4S binding domain; Region: Fer4; pfam00037
1008297007494	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1008297007495	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297007496	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1008297007497	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1008297007498	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297007499	dimerization interface [polypeptide binding]; other site
1008297007500	Histidine kinase; Region: HisKA_3; pfam07730
1008297007501	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297007502	ATP binding site [chemical binding]; other site
1008297007503	Mg2+ binding site [ion binding]; other site
1008297007504	G-X-G motif; other site
1008297007505	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1008297007506	Protein export membrane protein; Region: SecD_SecF; cl14618
1008297007507	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1008297007508	ArsC family; Region: ArsC; pfam03960
1008297007509	putative catalytic residues [active]
1008297007510	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1008297007511	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1008297007512	metal binding site [ion binding]; metal-binding site
1008297007513	dimer interface [polypeptide binding]; other site
1008297007514	hypothetical protein; Provisional; Region: PRK13664
1008297007515	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1008297007516	Helicase; Region: Helicase_RecD; pfam05127
1008297007517	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1008297007518	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1008297007519	Predicted metalloprotease [General function prediction only]; Region: COG2321
1008297007520	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1008297007521	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1008297007522	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1008297007523	ATP binding site [chemical binding]; other site
1008297007524	active site
1008297007525	substrate binding site [chemical binding]; other site
1008297007526	lipoprotein; Provisional; Region: PRK11679
1008297007527	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1008297007528	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1008297007529	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1008297007530	dimer interface [polypeptide binding]; other site
1008297007531	active site
1008297007532	catalytic residue [active]
1008297007533	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1008297007534	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1008297007535	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1008297007536	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1008297007537	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1008297007538	catalytic triad [active]
1008297007539	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1008297007540	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1008297007541	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1008297007542	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1008297007543	Peptidase family M48; Region: Peptidase_M48; cl12018
1008297007544	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1008297007545	ArsC family; Region: ArsC; pfam03960
1008297007546	catalytic residues [active]
1008297007547	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1008297007548	DNA replication initiation factor; Provisional; Region: PRK08084
1008297007549	uracil transporter; Provisional; Region: PRK10720
1008297007550	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1008297007551	active site
1008297007552	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1008297007553	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1008297007554	dimerization interface [polypeptide binding]; other site
1008297007555	putative ATP binding site [chemical binding]; other site
1008297007556	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1008297007557	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1008297007558	active site
1008297007559	substrate binding site [chemical binding]; other site
1008297007560	cosubstrate binding site; other site
1008297007561	catalytic site [active]
1008297007562	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1008297007563	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1008297007564	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1008297007565	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1008297007566	putative active site [active]
1008297007567	catalytic site [active]
1008297007568	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1008297007569	domain interface [polypeptide binding]; other site
1008297007570	active site
1008297007571	catalytic site [active]
1008297007572	exopolyphosphatase; Provisional; Region: PRK10854
1008297007573	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1008297007574	nucleotide binding site [chemical binding]; other site
1008297007575	MASE1; Region: MASE1; pfam05231
1008297007576	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1008297007577	diguanylate cyclase; Region: GGDEF; smart00267
1008297007578	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297007579	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1008297007580	GMP synthase; Reviewed; Region: guaA; PRK00074
1008297007581	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1008297007582	AMP/PPi binding site [chemical binding]; other site
1008297007583	candidate oxyanion hole; other site
1008297007584	catalytic triad [active]
1008297007585	potential glutamine specificity residues [chemical binding]; other site
1008297007586	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1008297007587	ATP Binding subdomain [chemical binding]; other site
1008297007588	Ligand Binding sites [chemical binding]; other site
1008297007589	Dimerization subdomain; other site
1008297007590	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1008297007591	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1008297007592	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1008297007593	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1008297007594	active site
1008297007595	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1008297007596	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1008297007597	generic binding surface II; other site
1008297007598	generic binding surface I; other site
1008297007599	AIDA autotransporter-like protein ShdA; Provisional; Region: PRK15319
1008297007600	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1008297007601	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1008297007602	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1008297007603	Autotransporter beta-domain; Region: Autotransporter; smart00869
1008297007604	putative outer membrane protein (RatB) (pseudogene)
1008297007605	outer membrane protein RatA; Provisional; Region: PRK15315
1008297007606	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1008297007607	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1008297007608	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1008297007609	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1008297007610	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1008297007611	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1008297007612	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1008297007613	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1008297007614	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1008297007615	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1008297007616	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1008297007617	intimin-like protein SinH; Provisional; Region: PRK15318
1008297007618	intimin-like protein SinH; Provisional; Region: PRK15318
1008297007619	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1008297007620	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1008297007621	GTP-binding protein Der; Reviewed; Region: PRK00093
1008297007622	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1008297007623	G1 box; other site
1008297007624	GTP/Mg2+ binding site [chemical binding]; other site
1008297007625	Switch I region; other site
1008297007626	G2 box; other site
1008297007627	Switch II region; other site
1008297007628	G3 box; other site
1008297007629	G4 box; other site
1008297007630	G5 box; other site
1008297007631	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1008297007632	G1 box; other site
1008297007633	GTP/Mg2+ binding site [chemical binding]; other site
1008297007634	Switch I region; other site
1008297007635	G2 box; other site
1008297007636	G3 box; other site
1008297007637	Switch II region; other site
1008297007638	G4 box; other site
1008297007639	G5 box; other site
1008297007640	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1008297007641	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
1008297007642	Trp docking motif [polypeptide binding]; other site
1008297007643	active site
1008297007644	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1008297007645	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1008297007646	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1008297007647	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1008297007648	dimer interface [polypeptide binding]; other site
1008297007649	motif 1; other site
1008297007650	active site
1008297007651	motif 2; other site
1008297007652	motif 3; other site
1008297007653	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1008297007654	anticodon binding site; other site
1008297007655	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1008297007656	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1008297007657	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1008297007658	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1008297007659	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1008297007660	non-specific DNA binding site [nucleotide binding]; other site
1008297007661	salt bridge; other site
1008297007662	sequence-specific DNA binding site [nucleotide binding]; other site
1008297007663	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1008297007664	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1008297007665	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297007666	FeS/SAM binding site; other site
1008297007667	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1008297007668	active site
1008297007669	multimer interface [polypeptide binding]; other site
1008297007670	4Fe-4S binding domain; Region: Fer4; pfam00037
1008297007671	hydrogenase 4 subunit H; Validated; Region: PRK08222
1008297007672	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1008297007673	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1008297007674	4Fe-4S binding domain; Region: Fer4; pfam00037
1008297007675	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1008297007676	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1008297007677	putative [Fe4-S4] binding site [ion binding]; other site
1008297007678	putative molybdopterin cofactor binding site [chemical binding]; other site
1008297007679	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1008297007680	putative molybdopterin cofactor binding site; other site
1008297007681	penicillin-binding protein 1C; Provisional; Region: PRK11240
1008297007682	Transglycosylase; Region: Transgly; pfam00912
1008297007683	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1008297007684	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1008297007685	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1008297007686	MG2 domain; Region: A2M_N; pfam01835
1008297007687	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1008297007688	surface patch; other site
1008297007689	thioester region; other site
1008297007690	specificity defining residues; other site
1008297007691	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1008297007692	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1008297007693	active site residue [active]
1008297007694	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1008297007695	active site residue [active]
1008297007696	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1008297007697	aminopeptidase B; Provisional; Region: PRK05015
1008297007698	Peptidase; Region: DUF3663; pfam12404
1008297007699	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1008297007700	interface (dimer of trimers) [polypeptide binding]; other site
1008297007701	Substrate-binding/catalytic site; other site
1008297007702	Zn-binding sites [ion binding]; other site
1008297007703	hypothetical protein; Provisional; Region: PRK10721
1008297007704	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1008297007705	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1008297007706	catalytic loop [active]
1008297007707	iron binding site [ion binding]; other site
1008297007708	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1008297007709	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1008297007710	nucleotide binding site [chemical binding]; other site
1008297007711	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1008297007712	SBD interface [polypeptide binding]; other site
1008297007713	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1008297007714	DnaJ domain; Region: DnaJ; pfam00226
1008297007715	HSP70 interaction site [polypeptide binding]; other site
1008297007716	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1008297007717	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1008297007718	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1008297007719	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1008297007720	trimerization site [polypeptide binding]; other site
1008297007721	active site
1008297007722	cysteine desulfurase; Provisional; Region: PRK14012
1008297007723	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1008297007724	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1008297007725	catalytic residue [active]
1008297007726	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1008297007727	Rrf2 family protein; Region: rrf2_super; TIGR00738
1008297007728	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1008297007729	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1008297007730	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1008297007731	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1008297007732	active site
1008297007733	dimerization interface [polypeptide binding]; other site
1008297007734	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1008297007735	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1008297007736	sulfite reductase, subunit A; Region: sulfite_red_A; TIGR02910
1008297007737	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1008297007738	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
1008297007739	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
1008297007740	FAD binding pocket [chemical binding]; other site
1008297007741	FAD binding motif [chemical binding]; other site
1008297007742	phosphate binding motif [ion binding]; other site
1008297007743	beta-alpha-beta structure motif; other site
1008297007744	NAD binding pocket [chemical binding]; other site
1008297007745	Iron coordination center [ion binding]; other site
1008297007746	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
1008297007747	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1008297007748	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1008297007749	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1008297007750	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
1008297007751	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1008297007752	PRD domain; Region: PRD; pfam00874
1008297007753	PRD domain; Region: PRD; pfam00874
1008297007754	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1008297007755	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297007756	putative substrate translocation pore; other site
1008297007757	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1008297007758	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1008297007759	dimer interface [polypeptide binding]; other site
1008297007760	active site
1008297007761	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1008297007762	folate binding site [chemical binding]; other site
1008297007763	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1008297007764	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1008297007765	heme-binding site [chemical binding]; other site
1008297007766	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1008297007767	FAD binding pocket [chemical binding]; other site
1008297007768	FAD binding motif [chemical binding]; other site
1008297007769	phosphate binding motif [ion binding]; other site
1008297007770	beta-alpha-beta structure motif; other site
1008297007771	NAD binding pocket [chemical binding]; other site
1008297007772	Heme binding  pocket [chemical binding]; other site
1008297007773	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
1008297007774	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297007775	DNA binding site [nucleotide binding]
1008297007776	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
1008297007777	lysine decarboxylase CadA; Provisional; Region: PRK15400
1008297007778	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1008297007779	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1008297007780	homodimer interface [polypeptide binding]; other site
1008297007781	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297007782	catalytic residue [active]
1008297007783	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1008297007784	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1008297007785	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297007786	putative substrate translocation pore; other site
1008297007787	POT family; Region: PTR2; pfam00854
1008297007788	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1008297007789	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1008297007790	response regulator GlrR; Provisional; Region: PRK15115
1008297007791	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297007792	active site
1008297007793	phosphorylation site [posttranslational modification]
1008297007794	intermolecular recognition site; other site
1008297007795	dimerization interface [polypeptide binding]; other site
1008297007796	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297007797	Walker A motif; other site
1008297007798	ATP binding site [chemical binding]; other site
1008297007799	Walker B motif; other site
1008297007800	arginine finger; other site
1008297007801	hypothetical protein; Provisional; Region: PRK10722
1008297007802	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1008297007803	HAMP domain; Region: HAMP; pfam00672
1008297007804	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297007805	dimer interface [polypeptide binding]; other site
1008297007806	phosphorylation site [posttranslational modification]
1008297007807	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297007808	ATP binding site [chemical binding]; other site
1008297007809	Mg2+ binding site [ion binding]; other site
1008297007810	G-X-G motif; other site
1008297007811	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1008297007812	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1008297007813	dimerization interface [polypeptide binding]; other site
1008297007814	ATP binding site [chemical binding]; other site
1008297007815	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
1008297007816	dimerization interface [polypeptide binding]; other site
1008297007817	ATP binding site [chemical binding]; other site
1008297007818	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1008297007819	putative active site [active]
1008297007820	catalytic triad [active]
1008297007821	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1008297007822	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297007823	substrate binding pocket [chemical binding]; other site
1008297007824	membrane-bound complex binding site; other site
1008297007825	hinge residues; other site
1008297007826	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1008297007827	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1008297007828	catalytic residue [active]
1008297007829	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1008297007830	nucleoside/Zn binding site; other site
1008297007831	dimer interface [polypeptide binding]; other site
1008297007832	catalytic motif [active]
1008297007833	hypothetical protein; Provisional; Region: PRK11590
1008297007834	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1008297007835	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1008297007836	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1008297007837	active site turn [active]
1008297007838	phosphorylation site [posttranslational modification]
1008297007839	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1008297007840	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1008297007841	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1008297007842	putative active site [active]
1008297007843	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1008297007844	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1008297007845	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1008297007846	putative active site [active]
1008297007847	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1008297007848	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1008297007849	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1008297007850	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1008297007851	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297007852	putative substrate translocation pore; other site
1008297007853	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297007854	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297007855	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1008297007856	dimerization interface [polypeptide binding]; other site
1008297007857	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1008297007858	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1008297007859	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1008297007860	active site
1008297007861	hydrophilic channel; other site
1008297007862	dimerization interface [polypeptide binding]; other site
1008297007863	catalytic residues [active]
1008297007864	active site lid [active]
1008297007865	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1008297007866	Recombination protein O N terminal; Region: RecO_N; pfam11967
1008297007867	Recombination protein O C terminal; Region: RecO_C; pfam02565
1008297007868	GTPase Era; Reviewed; Region: era; PRK00089
1008297007869	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1008297007870	G1 box; other site
1008297007871	GTP/Mg2+ binding site [chemical binding]; other site
1008297007872	Switch I region; other site
1008297007873	G2 box; other site
1008297007874	Switch II region; other site
1008297007875	G3 box; other site
1008297007876	G4 box; other site
1008297007877	G5 box; other site
1008297007878	KH domain; Region: KH_2; pfam07650
1008297007879	ribonuclease III; Reviewed; Region: rnc; PRK00102
1008297007880	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1008297007881	dimerization interface [polypeptide binding]; other site
1008297007882	active site
1008297007883	metal binding site [ion binding]; metal-binding site
1008297007884	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1008297007885	dsRNA binding site [nucleotide binding]; other site
1008297007886	signal peptidase I; Provisional; Region: PRK10861
1008297007887	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1008297007888	Catalytic site [active]
1008297007889	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1008297007890	GTP-binding protein LepA; Provisional; Region: PRK05433
1008297007891	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1008297007892	G1 box; other site
1008297007893	putative GEF interaction site [polypeptide binding]; other site
1008297007894	GTP/Mg2+ binding site [chemical binding]; other site
1008297007895	Switch I region; other site
1008297007896	G2 box; other site
1008297007897	G3 box; other site
1008297007898	Switch II region; other site
1008297007899	G4 box; other site
1008297007900	G5 box; other site
1008297007901	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1008297007902	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1008297007903	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1008297007904	type III secretion protein GogB; Provisional; Region: PRK15386
1008297007905	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1008297007906	Macro domain, Appr-1"-pase family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Appr_pase; cd02900
1008297007907	ADP-ribose binding site [chemical binding]; other site
1008297007908	putative active site [active]
1008297007909	dimer interface [polypeptide binding]; other site
1008297007910	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1008297007911	Phage Tail Collar Domain; Region: Collar; pfam07484
1008297007912	Phage-related protein, tail component [Function unknown]; Region: COG4733
1008297007913	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1008297007914	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1008297007915	Interdomain contacts; other site
1008297007916	Cytokine receptor motif; other site
1008297007917	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1008297007918	Fibronectin type III protein; Region: DUF3672; pfam12421
1008297007919	Phage-related protein, tail component [Function unknown]; Region: COG4723
1008297007920	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1008297007921	MPN+ (JAMM) motif; other site
1008297007922	Zinc-binding site [ion binding]; other site
1008297007923	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1008297007924	NlpC/P60 family; Region: NLPC_P60; cl17555
1008297007925	Phage-related protein [Function unknown]; Region: gp18; COG4672
1008297007926	Phage-related minor tail protein [Function unknown]; Region: COG5281
1008297007927	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1008297007928	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1008297007929	Minor tail protein T; Region: Phage_tail_T; cl05636
1008297007930	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
1008297007931	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1008297007932	Phage tail protein; Region: Phage_tail_3; pfam08813
1008297007933	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1008297007934	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1008297007935	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1008297007936	Probable transposase; Region: OrfB_IS605; pfam01385
1008297007937	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1008297007938	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1008297007939	DNA packaging protein FI; Region: Packaging_FI; pfam14000
1008297007940	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1008297007941	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
1008297007942	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1008297007943	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1008297007944	tandem repeat interface [polypeptide binding]; other site
1008297007945	oligomer interface [polypeptide binding]; other site
1008297007946	active site residues [active]
1008297007947	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1008297007948	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1008297007949	gpW; Region: gpW; pfam02831
1008297007950	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1008297007951	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
1008297007952	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
1008297007953	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1008297007954	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1008297007955	catalytic residues [active]
1008297007956	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1008297007957	PipA protein; Region: PipA; pfam07108
1008297007958	ORF6N domain; Region: ORF6N; pfam10543
1008297007959	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
1008297007960	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1008297007961	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1008297007962	DinI-like family; Region: DinI; pfam06183
1008297007963	Protein of unknown function (DUF550); Region: DUF550; pfam04447
1008297007964	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1008297007965	AAA domain; Region: AAA_31; pfam13614
1008297007966	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1008297007967	P-loop; other site
1008297007968	Magnesium ion binding site [ion binding]; other site
1008297007969	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1008297007970	Magnesium ion binding site [ion binding]; other site
1008297007971	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1008297007972	exonuclease VIII; Reviewed; Region: PRK09709
1008297007973	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
1008297007974	RecT family; Region: RecT; pfam03837
1008297007975	integrase; Provisional; Region: PRK09692
1008297007976	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1008297007977	active site
1008297007978	Int/Topo IB signature motif; other site
1008297007979	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1008297007980	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1008297007981	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1008297007982	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1008297007983	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1008297007984	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1008297007985	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1008297007986	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1008297007987	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1008297007988	DNA binding residues [nucleotide binding]
1008297007989	L-aspartate oxidase; Provisional; Region: PRK09077
1008297007990	L-aspartate oxidase; Provisional; Region: PRK06175
1008297007991	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1008297007992	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1008297007993	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297007994	S-adenosylmethionine binding site [chemical binding]; other site
1008297007995	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1008297007996	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1008297007997	ATP binding site [chemical binding]; other site
1008297007998	Mg++ binding site [ion binding]; other site
1008297007999	motif III; other site
1008297008000	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297008001	nucleotide binding region [chemical binding]; other site
1008297008002	ATP-binding site [chemical binding]; other site
1008297008003	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297008004	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297008005	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1008297008006	dimerization interface [polypeptide binding]; other site
1008297008007	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
1008297008008	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1008297008009	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1008297008010	ligand binding site [chemical binding]; other site
1008297008011	active site
1008297008012	UGI interface [polypeptide binding]; other site
1008297008013	catalytic site [active]
1008297008014	putative methyltransferase; Provisional; Region: PRK10864
1008297008015	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1008297008016	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1008297008017	thioredoxin 2; Provisional; Region: PRK10996
1008297008018	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1008297008019	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1008297008020	catalytic residues [active]
1008297008021	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1008297008022	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1008297008023	CoA binding domain; Region: CoA_binding_2; pfam13380
1008297008024	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1008297008025	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1008297008026	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1008297008027	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297008028	Coenzyme A binding pocket [chemical binding]; other site
1008297008029	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1008297008030	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1008297008031	domain interface [polypeptide binding]; other site
1008297008032	putative active site [active]
1008297008033	catalytic site [active]
1008297008034	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1008297008035	domain interface [polypeptide binding]; other site
1008297008036	putative active site [active]
1008297008037	catalytic site [active]
1008297008038	lipoprotein; Provisional; Region: PRK10759
1008297008039	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1008297008040	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297008041	putative substrate translocation pore; other site
1008297008042	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1008297008043	protein disaggregation chaperone; Provisional; Region: PRK10865
1008297008044	Clp amino terminal domain; Region: Clp_N; pfam02861
1008297008045	Clp amino terminal domain; Region: Clp_N; pfam02861
1008297008046	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297008047	Walker A motif; other site
1008297008048	ATP binding site [chemical binding]; other site
1008297008049	Walker B motif; other site
1008297008050	arginine finger; other site
1008297008051	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297008052	Walker A motif; other site
1008297008053	ATP binding site [chemical binding]; other site
1008297008054	Walker B motif; other site
1008297008055	arginine finger; other site
1008297008056	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1008297008057	hypothetical protein; Provisional; Region: PRK10723
1008297008058	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1008297008059	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1008297008060	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1008297008061	RNA binding surface [nucleotide binding]; other site
1008297008062	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1008297008063	active site
1008297008064	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1008297008065	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1008297008066	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1008297008067	30S subunit binding site; other site
1008297008068	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1008297008069	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1008297008070	Prephenate dehydratase; Region: PDT; pfam00800
1008297008071	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1008297008072	putative L-Phe binding site [chemical binding]; other site
1008297008073	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1008297008074	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1008297008075	Chorismate mutase type II; Region: CM_2; cl00693
1008297008076	prephenate dehydrogenase; Validated; Region: PRK08507
1008297008077	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1008297008078	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1008297008079	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1008297008080	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1008297008081	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1008297008082	metal binding site [ion binding]; metal-binding site
1008297008083	active site
1008297008084	I-site; other site
1008297008085	integrase; Provisional; Region: int; PHA02601
1008297008086	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1008297008087	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1008297008088	active site
1008297008089	DNA binding site [nucleotide binding]
1008297008090	Int/Topo IB signature motif; other site
1008297008091	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
1008297008092	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
1008297008093	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
1008297008094	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
1008297008095	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1008297008096	DksA-like zinc finger domain containing protein; Region: PHA00080
1008297008097	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1008297008098	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1008297008099	tail protein; Provisional; Region: D; PHA02561
1008297008100	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1008297008101	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1008297008102	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1008297008103	RimM N-terminal domain; Region: RimM; pfam01782
1008297008104	PRC-barrel domain; Region: PRC; pfam05239
1008297008105	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1008297008106	signal recognition particle protein; Provisional; Region: PRK10867
1008297008107	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1008297008108	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1008297008109	P loop; other site
1008297008110	GTP binding site [chemical binding]; other site
1008297008111	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1008297008112	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1008297008113	hypothetical protein; Provisional; Region: PRK11573
1008297008114	Domain of unknown function DUF21; Region: DUF21; pfam01595
1008297008115	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1008297008116	Transporter associated domain; Region: CorC_HlyC; smart01091
1008297008117	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1008297008118	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1008297008119	dimer interface [polypeptide binding]; other site
1008297008120	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1008297008121	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1008297008122	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1008297008123	recombination and repair protein; Provisional; Region: PRK10869
1008297008124	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1008297008125	Walker A/P-loop; other site
1008297008126	ATP binding site [chemical binding]; other site
1008297008127	Q-loop/lid; other site
1008297008128	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1008297008129	ABC transporter signature motif; other site
1008297008130	Walker B; other site
1008297008131	D-loop; other site
1008297008132	H-loop/switch region; other site
1008297008133	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1008297008134	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1008297008135	hypothetical protein; Validated; Region: PRK01777
1008297008136	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1008297008137	putative coenzyme Q binding site [chemical binding]; other site
1008297008138	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1008297008139	SmpB-tmRNA interface; other site
1008297008140	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008141	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008142	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008143	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008144	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008145	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008146	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008147	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008148	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008149	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008150	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008151	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1008297008152	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008153	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008154	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1008297008155	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008156	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297008157	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
1008297008158	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1008297008159	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1008297008160	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1008297008161	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297008162	Walker A/P-loop; other site
1008297008163	ATP binding site [chemical binding]; other site
1008297008164	Q-loop/lid; other site
1008297008165	ABC transporter signature motif; other site
1008297008166	Walker B; other site
1008297008167	D-loop; other site
1008297008168	H-loop/switch region; other site
1008297008169	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1008297008170	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297008171	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
1008297008172	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
1008297008173	Phage protein U [General function prediction only]; Region: COG3499
1008297008174	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1008297008175	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1008297008176	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1008297008177	major tail tube protein; Provisional; Region: FII; PHA02600
1008297008178	major tail sheath protein; Provisional; Region: FI; PHA02560
1008297008179	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1008297008180	SopE GEF domain; Region: SopE_GEF; pfam07487
1008297008181	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1008297008182	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1008297008183	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1008297008184	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1008297008185	baseplate assembly protein; Provisional; Region: J; PHA02568
1008297008186	baseplate wedge subunit; Provisional; Region: W; PHA02516
1008297008187	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1008297008188	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1008297008189	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1008297008190	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1008297008191	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1008297008192	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1008297008193	catalytic residues [active]
1008297008194	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
1008297008195	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1008297008196	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1008297008197	capsid protein; Provisional; Region: N; PHA02538
1008297008198	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
1008297008199	terminase ATPase subunit; Provisional; Region: P; PHA02535
1008297008200	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1008297008201	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
1008297008202	portal vertex protein; Provisional; Region: Q; PHA02536
1008297008203	Phage portal protein; Region: Phage_portal; pfam04860
1008297008204	DNA protecting protein DprA; Region: dprA; TIGR00732
1008297008205	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1008297008206	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1008297008207	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1008297008208	active site
1008297008209	DinI-like family; Region: DinI; pfam06183
1008297008210	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1008297008211	DNA adenine methylase (dam); Region: dam; TIGR00571
1008297008212	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1008297008213	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
1008297008214	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
1008297008215	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
1008297008216	integrase; Provisional; Region: int; PHA02601
1008297008217	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1008297008218	dimer interface [polypeptide binding]; other site
1008297008219	active site
1008297008220	catalytic residues [active]
1008297008221	Int/Topo IB signature motif; other site
1008297008222	GrpE; Region: GrpE; pfam01025
1008297008223	integrase; Provisional; Region: PRK09692
1008297008224	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1008297008225	active site
1008297008226	Int/Topo IB signature motif; other site
1008297008227	Predicted ATPase [General function prediction only]; Region: COG5293
1008297008228	Uncharacterized protein conserved in bacteria (DUF2326); Region: DUF2326; pfam10088
1008297008229	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
1008297008230	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
1008297008231	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
1008297008232	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1008297008233	active site
1008297008234	metal binding site [ion binding]; metal-binding site
1008297008235	interdomain interaction site; other site
1008297008236	D5 N terminal like; Region: D5_N; smart00885
1008297008237	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
1008297008238	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
1008297008239	bacteriophage integrase (pseudogene)
1008297008240	SEC-C motif; Region: SEC-C; pfam02810
1008297008241	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1008297008242	Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG5519
1008297008243	putative ATPase
1008297008244	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
1008297008245	Phosphotransferase system sorbitol-specific component IIC [Carbohydrate transport and metabolism]; Region: SrlA; COG3730
1008297008246	Phosphotransferase system sorbitol-specific component IIA [Carbohydrate transport and metabolism]; Region: SrlB; COG3731
1008297008247	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1008297008248	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1008297008249	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1008297008250	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1008297008251	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1008297008252	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1008297008253	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
1008297008254	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1008297008255	active site
1008297008256	dimer interface [polypeptide binding]; other site
1008297008257	magnesium binding site [ion binding]; other site
1008297008258	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
1008297008259	tetramer interface [polypeptide binding]; other site
1008297008260	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1008297008261	active site
1008297008262	Thermophilic glucose-6-phosphate isomerase and related metalloenzymes [Carbohydrate transport and metabolism / General function prediction only]; Region: COG2140
1008297008263	Glucose-6-phosphate isomerase (GPI); Region: GPI; pfam06560
1008297008264	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1008297008265	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1008297008266	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1008297008267	active site turn [active]
1008297008268	phosphorylation site [posttranslational modification]
1008297008269	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1008297008270	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1008297008271	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1008297008272	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
1008297008273	Integrase; Region: Integrase_1; pfam12835
1008297008274	putative transposase (pseudogene)
1008297008275	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1008297008276	DNA-binding interface [nucleotide binding]; DNA binding site
1008297008277	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3972
1008297008278	Family description; Region: UvrD_C_2; pfam13538
1008297008279	Transposase; Region: HTH_Tnp_1; cl17663
1008297008280	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1008297008281	putative transposase OrfB; Reviewed; Region: PHA02517
1008297008282	HTH-like domain; Region: HTH_21; pfam13276
1008297008283	Integrase core domain; Region: rve; pfam00665
1008297008284	Integrase core domain; Region: rve_2; pfam13333
1008297008285	Repressor of phase-1 flagellin; Region: Flag1_repress; pfam03614
1008297008286	flagellin; Validated; Region: PRK08026
1008297008287	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1008297008288	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
1008297008289	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1008297008290	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1008297008291	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1008297008292	catalytic residues [active]
1008297008293	catalytic nucleophile [active]
1008297008294	Presynaptic Site I dimer interface [polypeptide binding]; other site
1008297008295	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1008297008296	Synaptic Flat tetramer interface [polypeptide binding]; other site
1008297008297	Synaptic Site I dimer interface [polypeptide binding]; other site
1008297008298	DNA binding site [nucleotide binding]
1008297008299	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1008297008300	DNA-binding interface [nucleotide binding]; DNA binding site
1008297008301	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
1008297008302	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1008297008303	TDP-binding site; other site
1008297008304	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1008297008305	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297008306	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1008297008307	Walker A/P-loop; other site
1008297008308	ATP binding site [chemical binding]; other site
1008297008309	Q-loop/lid; other site
1008297008310	ABC transporter signature motif; other site
1008297008311	Walker B; other site
1008297008312	D-loop; other site
1008297008313	H-loop/switch region; other site
1008297008314	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1008297008315	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1008297008316	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297008317	Walker A/P-loop; other site
1008297008318	ATP binding site [chemical binding]; other site
1008297008319	Q-loop/lid; other site
1008297008320	ABC transporter signature motif; other site
1008297008321	Walker B; other site
1008297008322	D-loop; other site
1008297008323	H-loop/switch region; other site
1008297008324	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1008297008325	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1008297008326	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1008297008327	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1008297008328	outer membrane receptor FepA; Provisional; Region: PRK13528
1008297008329	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1008297008330	N-terminal plug; other site
1008297008331	ligand-binding site [chemical binding]; other site
1008297008332	secreted effector protein PipB2; Provisional; Region: PRK15196
1008297008333	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1008297008334	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1008297008335	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1008297008336	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1008297008337	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1008297008338	Protein of unknown function (DUF535); Region: DUF535; cl01128
1008297008339	Protein of unknown function (DUF535); Region: DUF535; cl01128
1008297008340	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
1008297008341	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1008297008342	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1008297008343	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
1008297008344	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1008297008345	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1008297008346	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297008347	dimer interface [polypeptide binding]; other site
1008297008348	phosphorylation site [posttranslational modification]
1008297008349	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297008350	ATP binding site [chemical binding]; other site
1008297008351	Mg2+ binding site [ion binding]; other site
1008297008352	G-X-G motif; other site
1008297008353	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
1008297008354	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297008355	active site
1008297008356	phosphorylation site [posttranslational modification]
1008297008357	intermolecular recognition site; other site
1008297008358	dimerization interface [polypeptide binding]; other site
1008297008359	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297008360	DNA binding site [nucleotide binding]
1008297008361	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1008297008362	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
1008297008363	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
1008297008364	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
1008297008365	substrate binding pocket [chemical binding]; other site
1008297008366	active site
1008297008367	iron coordination sites [ion binding]; other site
1008297008368	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1008297008369	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1008297008370	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
1008297008371	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1008297008372	tetramerization interface [polypeptide binding]; other site
1008297008373	NAD(P) binding site [chemical binding]; other site
1008297008374	catalytic residues [active]
1008297008375	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
1008297008376	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1008297008377	inhibitor-cofactor binding pocket; inhibition site
1008297008378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297008379	catalytic residue [active]
1008297008380	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
1008297008381	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
1008297008382	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297008383	DNA-binding site [nucleotide binding]; DNA binding site
1008297008384	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1008297008385	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1008297008386	bacterial OsmY and nodulation domain; Region: BON; smart00749
1008297008387	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1008297008388	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1008297008389	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1008297008390	dimerization interface [polypeptide binding]; other site
1008297008391	putative DNA binding site [nucleotide binding]; other site
1008297008392	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1008297008393	putative Zn2+ binding site [ion binding]; other site
1008297008394	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1008297008395	active site residue [active]
1008297008396	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1008297008397	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1008297008398	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1008297008399	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1008297008400	hypothetical protein; Provisional; Region: PRK10556
1008297008401	hypothetical protein; Provisional; Region: PRK10132
1008297008402	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1008297008403	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297008404	DNA-binding site [nucleotide binding]; DNA binding site
1008297008405	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297008406	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297008407	homodimer interface [polypeptide binding]; other site
1008297008408	catalytic residue [active]
1008297008409	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1008297008410	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1008297008411	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1008297008412	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1008297008413	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1008297008414	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1008297008415	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1008297008416	active site
1008297008417	dimer interface [polypeptide binding]; other site
1008297008418	catalytic residues [active]
1008297008419	effector binding site; other site
1008297008420	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1008297008421	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1008297008422	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1008297008423	dimer interface [polypeptide binding]; other site
1008297008424	putative radical transfer pathway; other site
1008297008425	diiron center [ion binding]; other site
1008297008426	tyrosyl radical; other site
1008297008427	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1008297008428	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1008297008429	Walker A/P-loop; other site
1008297008430	ATP binding site [chemical binding]; other site
1008297008431	Q-loop/lid; other site
1008297008432	ABC transporter signature motif; other site
1008297008433	Walker B; other site
1008297008434	D-loop; other site
1008297008435	H-loop/switch region; other site
1008297008436	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1008297008437	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1008297008438	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297008439	dimer interface [polypeptide binding]; other site
1008297008440	conserved gate region; other site
1008297008441	putative PBP binding loops; other site
1008297008442	ABC-ATPase subunit interface; other site
1008297008443	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1008297008444	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1008297008445	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1008297008446	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297008447	transcriptional repressor MprA; Provisional; Region: PRK10870
1008297008448	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1008297008449	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1008297008450	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1008297008451	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297008452	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1008297008453	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297008454	putative substrate translocation pore; other site
1008297008455	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297008456	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1008297008457	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1008297008458	glutamate--cysteine ligase; Provisional; Region: PRK02107
1008297008459	Predicted membrane protein [Function unknown]; Region: COG1238
1008297008460	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1008297008461	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297008462	motif II; other site
1008297008463	carbon storage regulator; Provisional; Region: PRK01712
1008297008464	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1008297008465	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1008297008466	motif 1; other site
1008297008467	active site
1008297008468	motif 2; other site
1008297008469	motif 3; other site
1008297008470	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1008297008471	DHHA1 domain; Region: DHHA1; pfam02272
1008297008472	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1008297008473	recombinase A; Provisional; Region: recA; PRK09354
1008297008474	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1008297008475	hexamer interface [polypeptide binding]; other site
1008297008476	Walker A motif; other site
1008297008477	ATP binding site [chemical binding]; other site
1008297008478	Walker B motif; other site
1008297008479	hypothetical protein; Validated; Region: PRK03661
1008297008480	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1008297008481	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1008297008482	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1008297008483	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
1008297008484	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1008297008485	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1008297008486	Nucleoside recognition; Region: Gate; pfam07670
1008297008487	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1008297008488	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1008297008489	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1008297008490	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1008297008491	putative NAD(P) binding site [chemical binding]; other site
1008297008492	active site
1008297008493	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1008297008494	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1008297008495	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1008297008496	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297008497	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1008297008498	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1008297008499	putative active site [active]
1008297008500	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1008297008501	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1008297008502	GAF domain; Region: GAF; pfam01590
1008297008503	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297008504	Walker A motif; other site
1008297008505	ATP binding site [chemical binding]; other site
1008297008506	Walker B motif; other site
1008297008507	arginine finger; other site
1008297008508	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1008297008509	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1008297008510	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1008297008511	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1008297008512	iron binding site [ion binding]; other site
1008297008513	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1008297008514	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1008297008515	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297008516	Acylphosphatase; Region: Acylphosphatase; pfam00708
1008297008517	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1008297008518	HypF finger; Region: zf-HYPF; pfam07503
1008297008519	HypF finger; Region: zf-HYPF; pfam07503
1008297008520	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1008297008521	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1008297008522	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1008297008523	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1008297008524	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1008297008525	nickel binding site [ion binding]; other site
1008297008526	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1008297008527	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1008297008528	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1008297008529	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1008297008530	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1008297008531	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1008297008532	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1008297008533	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1008297008534	NADH dehydrogenase; Region: NADHdh; cl00469
1008297008535	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1008297008536	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1008297008537	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1008297008538	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
1008297008539	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1008297008540	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1008297008541	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1008297008542	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1008297008543	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1008297008544	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1008297008545	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1008297008546	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1008297008547	dimerization interface [polypeptide binding]; other site
1008297008548	ATP binding site [chemical binding]; other site
1008297008549	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1008297008550	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1008297008551	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1008297008552	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297008553	Walker A motif; other site
1008297008554	ATP binding site [chemical binding]; other site
1008297008555	Walker B motif; other site
1008297008556	arginine finger; other site
1008297008557	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1008297008558	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1008297008559	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1008297008560	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1008297008561	metal binding site [ion binding]; metal-binding site
1008297008562	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1008297008563	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1008297008564	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1008297008565	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1008297008566	ABC-ATPase subunit  interface; other site
1008297008567	dimer interface [polypeptide binding]; other site
1008297008568	putative PBP binding regions; other site
1008297008569	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1008297008570	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1008297008571	ABC-ATPase subunit  interface; other site
1008297008572	dimer interface [polypeptide binding]; other site
1008297008573	putative PBP binding regions; other site
1008297008574	effector protein YopJ; Provisional; Region: PRK15371
1008297008575	transcriptional activator SprB; Provisional; Region: PRK15320
1008297008576	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1008297008577	transcriptional regulator SirC; Provisional; Region: PRK15044
1008297008578	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297008579	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
1008297008580	invasion protein OrgB; Provisional; Region: PRK15322
1008297008581	invasion protein OrgA; Provisional; Region: PRK15323
1008297008582	Bacterial type III secretion apparatus protein (OrgA_MxiK); Region: OrgA_MxiK; cl09716
1008297008583	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
1008297008584	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
1008297008585	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
1008297008586	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
1008297008587	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
1008297008588	transcriptional regulator HilD; Provisional; Region: PRK15185
1008297008589	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297008590	invasion protein regulator; Provisional; Region: PRK12370
1008297008591	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297008592	DNA binding site [nucleotide binding]
1008297008593	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1008297008594	binding surface
1008297008595	TPR motif; other site
1008297008596	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1008297008597	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1008297008598	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1008297008599	catalytic residue [active]
1008297008600	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
1008297008601	SicP binding; Region: SicP-binding; pfam09119
1008297008602	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
1008297008603	switch II binding region; other site
1008297008604	Rac1 P-loop interaction site [polypeptide binding]; other site
1008297008605	GTP binding residues [chemical binding]; other site
1008297008606	switch I binding region; other site
1008297008607	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
1008297008608	active site
1008297008609	chaperone protein SicP; Provisional; Region: PRK15329
1008297008610	putative acyl carrier protein IacP; Validated; Region: PRK08172
1008297008611	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
1008297008612	cell invasion protein SipD; Provisional; Region: PRK15330
1008297008613	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
1008297008614	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
1008297008615	chaperone protein SicA; Provisional; Region: PRK15331
1008297008616	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1008297008617	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1008297008618	type III secretion system protein SpaS; Validated; Region: PRK08156
1008297008619	type III secretion system protein SpaR; Provisional; Region: PRK15332
1008297008620	type III secretion system protein SpaQ; Provisional; Region: PRK15333
1008297008621	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
1008297008622	type III secretion system protein SpaO; Validated; Region: PRK08158
1008297008623	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1008297008624	antigen presentation protein SpaN; Provisional; Region: PRK15334
1008297008625	Surface presentation of antigens protein; Region: SPAN; pfam02510
1008297008626	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
1008297008627	ATP synthase SpaL; Validated; Region: PRK08149
1008297008628	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1008297008629	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1008297008630	Walker A motif; other site
1008297008631	ATP binding site [chemical binding]; other site
1008297008632	Walker B motif; other site
1008297008633	Invasion protein B family; Region: Invas_SpaK; cl04129
1008297008634	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
1008297008635	type III secretion system protein InvA; Provisional; Region: PRK15337
1008297008636	type III secretion system regulator InvE; Provisional; Region: PRK15338
1008297008637	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
1008297008638	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
1008297008639	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1008297008640	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1008297008641	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1008297008642	transcriptional regulator InvF; Provisional; Region: PRK15340
1008297008643	InvH outer membrane lipoprotein; Region: InvH; pfam04741
1008297008644	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1008297008645	putative transposase (pseudogene)
1008297008646	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1008297008647	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1008297008648	active site
1008297008649	metal binding site [ion binding]; metal-binding site
1008297008650	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1008297008651	MutS domain I; Region: MutS_I; pfam01624
1008297008652	MutS domain II; Region: MutS_II; pfam05188
1008297008653	MutS domain III; Region: MutS_III; pfam05192
1008297008654	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1008297008655	Walker A/P-loop; other site
1008297008656	ATP binding site [chemical binding]; other site
1008297008657	Q-loop/lid; other site
1008297008658	ABC transporter signature motif; other site
1008297008659	Walker B; other site
1008297008660	D-loop; other site
1008297008661	H-loop/switch region; other site
1008297008662	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1008297008663	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297008664	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1008297008665	putative substrate translocation pore; other site
1008297008666	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297008667	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297008668	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1008297008669	putative effector binding pocket; other site
1008297008670	dimerization interface [polypeptide binding]; other site
1008297008671	GntP family permease; Region: GntP_permease; pfam02447
1008297008672	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1008297008673	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1008297008674	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
1008297008675	putative NAD(P) binding site [chemical binding]; other site
1008297008676	active site
1008297008677	putative substrate binding site [chemical binding]; other site
1008297008678	hypothetical protein; Provisional; Region: PRK09989
1008297008679	putative aldolase; Validated; Region: PRK08130
1008297008680	intersubunit interface [polypeptide binding]; other site
1008297008681	active site
1008297008682	Zn2+ binding site [ion binding]; other site
1008297008683	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1008297008684	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1008297008685	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1008297008686	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1008297008687	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1008297008688	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297008689	MarR family; Region: MarR_2; cl17246
1008297008690	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1008297008691	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1008297008692	Flavoprotein; Region: Flavoprotein; pfam02441
1008297008693	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1008297008694	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1008297008695	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1008297008696	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1008297008697	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1008297008698	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1008297008699	DNA binding residues [nucleotide binding]
1008297008700	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
1008297008701	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1008297008702	Peptidase family M23; Region: Peptidase_M23; pfam01551
1008297008703	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1008297008704	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297008705	S-adenosylmethionine binding site [chemical binding]; other site
1008297008706	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1008297008707	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1008297008708	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1008297008709	Permutation of conserved domain; other site
1008297008710	active site
1008297008711	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1008297008712	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1008297008713	homotrimer interaction site [polypeptide binding]; other site
1008297008714	zinc binding site [ion binding]; other site
1008297008715	CDP-binding sites; other site
1008297008716	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1008297008717	substrate binding site; other site
1008297008718	dimer interface; other site
1008297008719	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1008297008720	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1008297008721	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
1008297008722	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1008297008723	ligand-binding site [chemical binding]; other site
1008297008724	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1008297008725	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1008297008726	CysD dimerization site [polypeptide binding]; other site
1008297008727	G1 box; other site
1008297008728	putative GEF interaction site [polypeptide binding]; other site
1008297008729	GTP/Mg2+ binding site [chemical binding]; other site
1008297008730	Switch I region; other site
1008297008731	G2 box; other site
1008297008732	G3 box; other site
1008297008733	Switch II region; other site
1008297008734	G4 box; other site
1008297008735	G5 box; other site
1008297008736	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1008297008737	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1008297008738	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1008297008739	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1008297008740	Active Sites [active]
1008297008741	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1008297008742	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1008297008743	metal binding site [ion binding]; metal-binding site
1008297008744	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
1008297008745	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
1008297008746	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
1008297008747	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
1008297008748	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
1008297008749	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
1008297008750	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09731
1008297008751	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
1008297008752	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1008297008753	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
1008297008754	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1008297008755	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
1008297008756	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1008297008757	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1008297008758	Active Sites [active]
1008297008759	sulfite reductase subunit beta; Provisional; Region: PRK13504
1008297008760	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1008297008761	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1008297008762	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1008297008763	Flavodoxin; Region: Flavodoxin_1; pfam00258
1008297008764	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1008297008765	FAD binding pocket [chemical binding]; other site
1008297008766	FAD binding motif [chemical binding]; other site
1008297008767	catalytic residues [active]
1008297008768	NAD binding pocket [chemical binding]; other site
1008297008769	phosphate binding motif [ion binding]; other site
1008297008770	beta-alpha-beta structure motif; other site
1008297008771	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1008297008772	active site
1008297008773	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1008297008774	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1008297008775	enolase; Provisional; Region: eno; PRK00077
1008297008776	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1008297008777	dimer interface [polypeptide binding]; other site
1008297008778	metal binding site [ion binding]; metal-binding site
1008297008779	substrate binding pocket [chemical binding]; other site
1008297008780	CTP synthetase; Validated; Region: pyrG; PRK05380
1008297008781	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1008297008782	Catalytic site [active]
1008297008783	active site
1008297008784	UTP binding site [chemical binding]; other site
1008297008785	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1008297008786	active site
1008297008787	putative oxyanion hole; other site
1008297008788	catalytic triad [active]
1008297008789	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1008297008790	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1008297008791	homodimer interface [polypeptide binding]; other site
1008297008792	metal binding site [ion binding]; metal-binding site
1008297008793	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1008297008794	homodimer interface [polypeptide binding]; other site
1008297008795	active site
1008297008796	putative chemical substrate binding site [chemical binding]; other site
1008297008797	metal binding site [ion binding]; metal-binding site
1008297008798	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1008297008799	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
1008297008800	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1008297008801	HD domain; Region: HD_4; pfam13328
1008297008802	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1008297008803	synthetase active site [active]
1008297008804	NTP binding site [chemical binding]; other site
1008297008805	metal binding site [ion binding]; metal-binding site
1008297008806	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1008297008807	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1008297008808	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1008297008809	TRAM domain; Region: TRAM; pfam01938
1008297008810	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297008811	S-adenosylmethionine binding site [chemical binding]; other site
1008297008812	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1008297008813	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1008297008814	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297008815	dimerization interface [polypeptide binding]; other site
1008297008816	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297008817	dimer interface [polypeptide binding]; other site
1008297008818	phosphorylation site [posttranslational modification]
1008297008819	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297008820	ATP binding site [chemical binding]; other site
1008297008821	Mg2+ binding site [ion binding]; other site
1008297008822	G-X-G motif; other site
1008297008823	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1008297008824	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297008825	active site
1008297008826	phosphorylation site [posttranslational modification]
1008297008827	intermolecular recognition site; other site
1008297008828	dimerization interface [polypeptide binding]; other site
1008297008829	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1008297008830	putative binding surface; other site
1008297008831	active site
1008297008832	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1008297008833	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1008297008834	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1008297008835	active site
1008297008836	tetramer interface [polypeptide binding]; other site
1008297008837	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1008297008838	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1008297008839	active site
1008297008840	tetramer interface [polypeptide binding]; other site
1008297008841	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297008842	D-galactonate transporter; Region: 2A0114; TIGR00893
1008297008843	putative substrate translocation pore; other site
1008297008844	flavodoxin; Provisional; Region: PRK08105
1008297008845	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1008297008846	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1008297008847	probable active site [active]
1008297008848	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
1008297008849	SecY interacting protein Syd; Provisional; Region: PRK04968
1008297008850	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1008297008851	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1008297008852	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1008297008853	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1008297008854	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1008297008855	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1008297008856	serine transporter; Region: stp; TIGR00814
1008297008857	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1008297008858	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1008297008859	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1008297008860	flap endonuclease-like protein; Provisional; Region: PRK09482
1008297008861	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1008297008862	active site
1008297008863	metal binding site 1 [ion binding]; metal-binding site
1008297008864	putative 5' ssDNA interaction site; other site
1008297008865	metal binding site 3; metal-binding site
1008297008866	metal binding site 2 [ion binding]; metal-binding site
1008297008867	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1008297008868	putative DNA binding site [nucleotide binding]; other site
1008297008869	putative metal binding site [ion binding]; other site
1008297008870	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1008297008871	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1008297008872	dimer interface [polypeptide binding]; other site
1008297008873	active site
1008297008874	metal binding site [ion binding]; metal-binding site
1008297008875	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1008297008876	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1008297008877	intersubunit interface [polypeptide binding]; other site
1008297008878	active site
1008297008879	Zn2+ binding site [ion binding]; other site
1008297008880	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1008297008881	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297008882	putative substrate translocation pore; other site
1008297008883	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1008297008884	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
1008297008885	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1008297008886	trimer interface [polypeptide binding]; other site
1008297008887	substrate binding site [chemical binding]; other site
1008297008888	Mn binding site [ion binding]; other site
1008297008889	L-fuculokinase; Provisional; Region: PRK10331
1008297008890	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1008297008891	nucleotide binding site [chemical binding]; other site
1008297008892	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
1008297008893	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1008297008894	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1008297008895	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297008896	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1008297008897	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1008297008898	hypothetical protein; Provisional; Region: PRK10873
1008297008899	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1008297008900	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297008901	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1008297008902	dimerization interface [polypeptide binding]; other site
1008297008903	substrate binding pocket [chemical binding]; other site
1008297008904	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1008297008905	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1008297008906	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1008297008907	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1008297008908	catalytic residue [active]
1008297008909	CsdA-binding activator; Provisional; Region: PRK15019
1008297008910	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1008297008911	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1008297008912	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1008297008913	putative ATP binding site [chemical binding]; other site
1008297008914	putative substrate interface [chemical binding]; other site
1008297008915	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1008297008916	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1008297008917	MltA specific insert domain; Region: MltA; pfam03562
1008297008918	3D domain; Region: 3D; pfam06725
1008297008919	AMIN domain; Region: AMIN; pfam11741
1008297008920	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1008297008921	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1008297008922	active site
1008297008923	metal binding site [ion binding]; metal-binding site
1008297008924	N-acetylglutamate synthase; Validated; Region: PRK05279
1008297008925	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1008297008926	putative feedback inhibition sensing region; other site
1008297008927	putative nucleotide binding site [chemical binding]; other site
1008297008928	putative substrate binding site [chemical binding]; other site
1008297008929	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297008930	Coenzyme A binding pocket [chemical binding]; other site
1008297008931	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1008297008932	AAA domain; Region: AAA_30; pfam13604
1008297008933	Family description; Region: UvrD_C_2; pfam13538
1008297008934	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1008297008935	protease3; Provisional; Region: PRK15101
1008297008936	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1008297008937	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1008297008938	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1008297008939	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1008297008940	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1008297008941	hypothetical protein; Provisional; Region: PRK10332
1008297008942	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1008297008943	hypothetical protein; Provisional; Region: PRK11521
1008297008944	hypothetical protein; Provisional; Region: PRK10557
1008297008945	hypothetical protein; Provisional; Region: PRK10506
1008297008946	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1008297008947	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1008297008948	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1008297008949	dimerization interface [polypeptide binding]; other site
1008297008950	active site
1008297008951	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1008297008952	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1008297008953	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1008297008954	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1008297008955	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1008297008956	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1008297008957	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1008297008958	putative active site [active]
1008297008959	Ap4A binding site [chemical binding]; other site
1008297008960	nudix motif; other site
1008297008961	putative metal binding site [ion binding]; other site
1008297008962	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1008297008963	putative DNA-binding cleft [nucleotide binding]; other site
1008297008964	putative DNA clevage site; other site
1008297008965	molecular lever; other site
1008297008966	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1008297008967	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1008297008968	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1008297008969	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1008297008970	active site
1008297008971	catalytic tetrad [active]
1008297008972	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1008297008973	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297008974	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1008297008975	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1008297008976	putative acyl-acceptor binding pocket; other site
1008297008977	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1008297008978	acyl-activating enzyme (AAE) consensus motif; other site
1008297008979	putative AMP binding site [chemical binding]; other site
1008297008980	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1008297008981	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297008982	DNA binding site [nucleotide binding]
1008297008983	domain linker motif; other site
1008297008984	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1008297008985	dimerization interface (closed form) [polypeptide binding]; other site
1008297008986	ligand binding site [chemical binding]; other site
1008297008987	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1008297008988	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297008989	DNA binding site [nucleotide binding]
1008297008990	domain linker motif; other site
1008297008991	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1008297008992	dimerization interface (closed form) [polypeptide binding]; other site
1008297008993	ligand binding site [chemical binding]; other site
1008297008994	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1008297008995	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1008297008996	active site
1008297008997	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1008297008998	substrate binding site [chemical binding]; other site
1008297008999	catalytic residues [active]
1008297009000	dimer interface [polypeptide binding]; other site
1008297009001	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1008297009002	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297009003	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297009004	dimerization interface [polypeptide binding]; other site
1008297009005	putative racemase; Provisional; Region: PRK10200
1008297009006	aspartate racemase; Region: asp_race; TIGR00035
1008297009007	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1008297009008	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297009009	putative substrate translocation pore; other site
1008297009010	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297009011	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1008297009012	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1008297009013	NADP binding site [chemical binding]; other site
1008297009014	homodimer interface [polypeptide binding]; other site
1008297009015	active site
1008297009016	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1008297009017	putative acyltransferase; Provisional; Region: PRK05790
1008297009018	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1008297009019	dimer interface [polypeptide binding]; other site
1008297009020	active site
1008297009021	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297009022	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297009023	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1008297009024	dimerization interface [polypeptide binding]; other site
1008297009025	Predicted membrane protein [Function unknown]; Region: COG4125
1008297009026	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1008297009027	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1008297009028	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1008297009029	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1008297009030	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1008297009031	putative metal binding site [ion binding]; other site
1008297009032	putative homodimer interface [polypeptide binding]; other site
1008297009033	putative homotetramer interface [polypeptide binding]; other site
1008297009034	putative homodimer-homodimer interface [polypeptide binding]; other site
1008297009035	putative allosteric switch controlling residues; other site
1008297009036	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
1008297009037	transcriptional activator SprB; Provisional; Region: PRK15320
1008297009038	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14600
1008297009039	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
1008297009040	Fimbrial protein; Region: Fimbrial; pfam00419
1008297009041	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
1008297009042	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297009043	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297009044	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
1008297009045	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297009046	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297009047	PapC C-terminal domain; Region: PapC_C; pfam13953
1008297009048	fimbrial protein StdA; Provisional; Region: PRK15210
1008297009049	hypothetical protein; Provisional; Region: PRK10316
1008297009050	YfdX protein; Region: YfdX; pfam10938
1008297009051	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1008297009052	oligomeric interface; other site
1008297009053	putative active site [active]
1008297009054	homodimer interface [polypeptide binding]; other site
1008297009055	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
1008297009056	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1008297009057	Peptidase family M23; Region: Peptidase_M23; pfam01551
1008297009058	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1008297009059	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1008297009060	active site
1008297009061	metal binding site [ion binding]; metal-binding site
1008297009062	nudix motif; other site
1008297009063	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1008297009064	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1008297009065	dimer interface [polypeptide binding]; other site
1008297009066	putative anticodon binding site; other site
1008297009067	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1008297009068	motif 1; other site
1008297009069	active site
1008297009070	motif 2; other site
1008297009071	motif 3; other site
1008297009072	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1008297009073	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1008297009074	RF-1 domain; Region: RF-1; pfam00472
1008297009075	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1008297009076	DHH family; Region: DHH; pfam01368
1008297009077	DHHA1 domain; Region: DHHA1; pfam02272
1008297009078	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1008297009079	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1008297009080	dimerization domain [polypeptide binding]; other site
1008297009081	dimer interface [polypeptide binding]; other site
1008297009082	catalytic residues [active]
1008297009083	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1008297009084	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1008297009085	active site
1008297009086	Int/Topo IB signature motif; other site
1008297009087	flavodoxin FldB; Provisional; Region: PRK12359
1008297009088	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1008297009089	hypothetical protein; Provisional; Region: PRK10878
1008297009090	putative global regulator; Reviewed; Region: PRK09559
1008297009091	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1008297009092	hemolysin; Provisional; Region: PRK15087
1008297009093	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1008297009094	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1008297009095	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1008297009096	beta-galactosidase; Region: BGL; TIGR03356
1008297009097	glycine dehydrogenase; Provisional; Region: PRK05367
1008297009098	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1008297009099	tetramer interface [polypeptide binding]; other site
1008297009100	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297009101	catalytic residue [active]
1008297009102	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1008297009103	tetramer interface [polypeptide binding]; other site
1008297009104	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297009105	catalytic residue [active]
1008297009106	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1008297009107	lipoyl attachment site [posttranslational modification]; other site
1008297009108	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1008297009109	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1008297009110	oxidoreductase; Provisional; Region: PRK08013
1008297009111	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1008297009112	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1008297009113	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1008297009114	proline aminopeptidase P II; Provisional; Region: PRK10879
1008297009115	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1008297009116	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1008297009117	active site
1008297009118	hypothetical protein; Reviewed; Region: PRK01736
1008297009119	Cell division protein ZapA; Region: ZapA; cl01146
1008297009120	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1008297009121	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1008297009122	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1008297009123	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1008297009124	ligand binding site [chemical binding]; other site
1008297009125	NAD binding site [chemical binding]; other site
1008297009126	tetramer interface [polypeptide binding]; other site
1008297009127	catalytic site [active]
1008297009128	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1008297009129	L-serine binding site [chemical binding]; other site
1008297009130	ACT domain interface; other site
1008297009131	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1008297009132	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1008297009133	active site
1008297009134	dimer interface [polypeptide binding]; other site
1008297009135	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1008297009136	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297009137	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1008297009138	putative dimerization interface [polypeptide binding]; other site
1008297009139	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1008297009140	oxidative stress defense protein; Provisional; Region: PRK11087
1008297009141	arginine exporter protein; Provisional; Region: PRK09304
1008297009142	mechanosensitive channel MscS; Provisional; Region: PRK10334
1008297009143	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1008297009144	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1008297009145	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1008297009146	active site
1008297009147	intersubunit interface [polypeptide binding]; other site
1008297009148	zinc binding site [ion binding]; other site
1008297009149	Na+ binding site [ion binding]; other site
1008297009150	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1008297009151	Phosphoglycerate kinase; Region: PGK; pfam00162
1008297009152	substrate binding site [chemical binding]; other site
1008297009153	hinge regions; other site
1008297009154	ADP binding site [chemical binding]; other site
1008297009155	catalytic site [active]
1008297009156	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1008297009157	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1008297009158	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1008297009159	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1008297009160	trimer interface [polypeptide binding]; other site
1008297009161	putative Zn binding site [ion binding]; other site
1008297009162	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1008297009163	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1008297009164	Walker A/P-loop; other site
1008297009165	ATP binding site [chemical binding]; other site
1008297009166	ABC transporter; Region: ABC_tran; pfam00005
1008297009167	Q-loop/lid; other site
1008297009168	ABC transporter signature motif; other site
1008297009169	Walker B; other site
1008297009170	D-loop; other site
1008297009171	H-loop/switch region; other site
1008297009172	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1008297009173	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1008297009174	Walker A/P-loop; other site
1008297009175	ATP binding site [chemical binding]; other site
1008297009176	Q-loop/lid; other site
1008297009177	ABC transporter signature motif; other site
1008297009178	Walker B; other site
1008297009179	D-loop; other site
1008297009180	H-loop/switch region; other site
1008297009181	transketolase; Reviewed; Region: PRK12753
1008297009182	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1008297009183	TPP-binding site [chemical binding]; other site
1008297009184	dimer interface [polypeptide binding]; other site
1008297009185	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1008297009186	PYR/PP interface [polypeptide binding]; other site
1008297009187	dimer interface [polypeptide binding]; other site
1008297009188	TPP binding site [chemical binding]; other site
1008297009189	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1008297009190	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1008297009191	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1008297009192	agmatinase; Region: agmatinase; TIGR01230
1008297009193	oligomer interface [polypeptide binding]; other site
1008297009194	putative active site [active]
1008297009195	Mn binding site [ion binding]; other site
1008297009196	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1008297009197	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1008297009198	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
1008297009199	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1008297009200	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1008297009201	putative NAD(P) binding site [chemical binding]; other site
1008297009202	catalytic Zn binding site [ion binding]; other site
1008297009203	structural Zn binding site [ion binding]; other site
1008297009204	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1008297009205	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1008297009206	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1008297009207	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1008297009208	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297009209	DNA-binding site [nucleotide binding]; DNA binding site
1008297009210	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1008297009211	DNA phosphorothioation-dependent restriction protein DptH; Region: dnd_assoc_2; TIGR03237
1008297009212	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1008297009213	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1008297009214	dimer interface [polypeptide binding]; other site
1008297009215	active site
1008297009216	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1008297009217	catalytic residues [active]
1008297009218	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1008297009219	Virulence promoting factor; Region: YqgB; pfam11036
1008297009220	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1008297009221	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1008297009222	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1008297009223	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1008297009224	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1008297009225	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297009226	putative substrate translocation pore; other site
1008297009227	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297009228	hypothetical protein; Provisional; Region: PRK04860
1008297009229	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1008297009230	DNA-specific endonuclease I; Provisional; Region: PRK15137
1008297009231	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1008297009232	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1008297009233	RNA methyltransferase, RsmE family; Region: TIGR00046
1008297009234	glutathione synthetase; Provisional; Region: PRK05246
1008297009235	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1008297009236	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1008297009237	hypothetical protein; Validated; Region: PRK00228
1008297009238	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1008297009239	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1008297009240	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1008297009241	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1008297009242	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1008297009243	Walker A motif; other site
1008297009244	ATP binding site [chemical binding]; other site
1008297009245	Walker B motif; other site
1008297009246	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1008297009247	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1008297009248	catalytic residue [active]
1008297009249	YGGT family; Region: YGGT; pfam02325
1008297009250	YGGT family; Region: YGGT; pfam02325
1008297009251	hypothetical protein; Validated; Region: PRK05090
1008297009252	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1008297009253	active site
1008297009254	dimerization interface [polypeptide binding]; other site
1008297009255	putative oxygen-independent coproporphyrinogen III oxidase; Region: hemN_rel; TIGR00539
1008297009256	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297009257	FeS/SAM binding site; other site
1008297009258	HemN C-terminal domain; Region: HemN_C; pfam06969
1008297009259	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
1008297009260	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
1008297009261	homodimer interface [polypeptide binding]; other site
1008297009262	active site
1008297009263	hypothetical protein; Provisional; Region: PRK10626
1008297009264	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1008297009265	hypothetical protein; Provisional; Region: PRK11702
1008297009266	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1008297009267	adenine DNA glycosylase; Provisional; Region: PRK10880
1008297009268	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1008297009269	minor groove reading motif; other site
1008297009270	helix-hairpin-helix signature motif; other site
1008297009271	substrate binding pocket [chemical binding]; other site
1008297009272	active site
1008297009273	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1008297009274	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1008297009275	DNA binding and oxoG recognition site [nucleotide binding]
1008297009276	oxidative damage protection protein; Provisional; Region: PRK05408
1008297009277	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1008297009278	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1008297009279	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1008297009280	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1008297009281	catalytic residue [active]
1008297009282	nucleoside transporter; Region: 2A0110; TIGR00889
1008297009283	ornithine decarboxylase; Provisional; Region: PRK13578
1008297009284	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1008297009285	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1008297009286	homodimer interface [polypeptide binding]; other site
1008297009287	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297009288	catalytic residue [active]
1008297009289	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1008297009290	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
1008297009291	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
1008297009292	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1008297009293	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1008297009294	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
1008297009295	putative active site [active]
1008297009296	putative catalytic site [active]
1008297009297	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1008297009298	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1008297009299	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297009300	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
1008297009301	putative dimerization interface [polypeptide binding]; other site
1008297009302	putative substrate binding pocket [chemical binding]; other site
1008297009303	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1008297009304	Sulfatase; Region: Sulfatase; pfam00884
1008297009305	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1008297009306	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297009307	FeS/SAM binding site; other site
1008297009308	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1008297009309	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1008297009310	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297009311	DNA binding residues [nucleotide binding]
1008297009312	dimerization interface [polypeptide binding]; other site
1008297009313	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
1008297009314	Amino acid permease; Region: AA_permease_2; pfam13520
1008297009315	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
1008297009316	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1008297009317	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1008297009318	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
1008297009319	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1008297009320	NAD(P) binding site [chemical binding]; other site
1008297009321	catalytic residues [active]
1008297009322	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
1008297009323	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1008297009324	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1008297009325	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1008297009326	tetramer interface [polypeptide binding]; other site
1008297009327	active site
1008297009328	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1008297009329	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
1008297009330	putative active site [active]
1008297009331	catalytic triad [active]
1008297009332	putative dimer interface [polypeptide binding]; other site
1008297009333	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297009334	D-galactonate transporter; Region: 2A0114; TIGR00893
1008297009335	putative substrate translocation pore; other site
1008297009336	mannonate dehydratase; Provisional; Region: PRK03906
1008297009337	mannonate dehydratase; Region: uxuA; TIGR00695
1008297009338	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1008297009339	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1008297009340	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1008297009341	Glucuronate isomerase; Region: UxaC; pfam02614
1008297009342	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1008297009343	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1008297009344	dimer interface [polypeptide binding]; other site
1008297009345	putative CheW interface [polypeptide binding]; other site
1008297009346	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1008297009347	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1008297009348	CHAP domain; Region: CHAP; pfam05257
1008297009349	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1008297009350	putative S-transferase; Provisional; Region: PRK11752
1008297009351	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1008297009352	C-terminal domain interface [polypeptide binding]; other site
1008297009353	GSH binding site (G-site) [chemical binding]; other site
1008297009354	dimer interface [polypeptide binding]; other site
1008297009355	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1008297009356	dimer interface [polypeptide binding]; other site
1008297009357	N-terminal domain interface [polypeptide binding]; other site
1008297009358	active site
1008297009359	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1008297009360	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
1008297009361	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1008297009362	putative ligand binding residues [chemical binding]; other site
1008297009363	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1008297009364	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
1008297009365	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1008297009366	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
1008297009367	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
1008297009368	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1008297009369	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1008297009370	putative substrate-binding site; other site
1008297009371	nickel binding site [ion binding]; other site
1008297009372	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1008297009373	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1008297009374	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
1008297009375	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1008297009376	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
1008297009377	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1008297009378	hydrogenase 2 small subunit; Provisional; Region: PRK10468
1008297009379	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1008297009380	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1008297009381	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
1008297009382	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1008297009383	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297009384	dimerization interface [polypeptide binding]; other site
1008297009385	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1008297009386	dimer interface [polypeptide binding]; other site
1008297009387	putative CheW interface [polypeptide binding]; other site
1008297009388	hypothetical protein; Provisional; Region: PRK05208
1008297009389	oxidoreductase; Provisional; Region: PRK07985
1008297009390	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1008297009391	NAD binding site [chemical binding]; other site
1008297009392	metal binding site [ion binding]; metal-binding site
1008297009393	active site
1008297009394	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1008297009395	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1008297009396	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1008297009397	cystathionine beta-lyase; Provisional; Region: PRK08114
1008297009398	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1008297009399	homodimer interface [polypeptide binding]; other site
1008297009400	substrate-cofactor binding pocket; other site
1008297009401	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297009402	catalytic residue [active]
1008297009403	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1008297009404	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1008297009405	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1008297009406	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1008297009407	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297009408	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297009409	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1008297009410	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1008297009411	dimer interface [polypeptide binding]; other site
1008297009412	active site
1008297009413	metal binding site [ion binding]; metal-binding site
1008297009414	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1008297009415	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1008297009416	active site
1008297009417	catalytic tetrad [active]
1008297009418	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1008297009419	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1008297009420	transmembrane helices; other site
1008297009421	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1008297009422	nucleotide binding site/active site [active]
1008297009423	catalytic residue [active]
1008297009424	hypothetical protein; Provisional; Region: PRK01254
1008297009425	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1008297009426	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1008297009427	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1008297009428	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1008297009429	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1008297009430	DctM-like transporters; Region: DctM; pfam06808
1008297009431	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
1008297009432	FtsI repressor; Provisional; Region: PRK10883
1008297009433	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1008297009434	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1008297009435	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1008297009436	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1008297009437	putative acyl-acceptor binding pocket; other site
1008297009438	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
1008297009439	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1008297009440	CAP-like domain; other site
1008297009441	active site
1008297009442	primary dimer interface [polypeptide binding]; other site
1008297009443	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1008297009444	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1008297009445	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297009446	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1008297009447	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1008297009448	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1008297009449	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297009450	active site
1008297009451	phosphorylation site [posttranslational modification]
1008297009452	intermolecular recognition site; other site
1008297009453	dimerization interface [polypeptide binding]; other site
1008297009454	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297009455	DNA binding site [nucleotide binding]
1008297009456	sensor protein QseC; Provisional; Region: PRK10337
1008297009457	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1008297009458	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297009459	dimer interface [polypeptide binding]; other site
1008297009460	phosphorylation site [posttranslational modification]
1008297009461	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297009462	ATP binding site [chemical binding]; other site
1008297009463	Mg2+ binding site [ion binding]; other site
1008297009464	G-X-G motif; other site
1008297009465	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1008297009466	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1008297009467	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1008297009468	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297009469	ATP binding site [chemical binding]; other site
1008297009470	Mg2+ binding site [ion binding]; other site
1008297009471	G-X-G motif; other site
1008297009472	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1008297009473	anchoring element; other site
1008297009474	dimer interface [polypeptide binding]; other site
1008297009475	ATP binding site [chemical binding]; other site
1008297009476	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1008297009477	active site
1008297009478	metal binding site [ion binding]; metal-binding site
1008297009479	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1008297009480	esterase YqiA; Provisional; Region: PRK11071
1008297009481	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1008297009482	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1008297009483	active site
1008297009484	metal binding site [ion binding]; metal-binding site
1008297009485	hexamer interface [polypeptide binding]; other site
1008297009486	putative dehydrogenase; Provisional; Region: PRK11039
1008297009487	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1008297009488	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1008297009489	dimer interface [polypeptide binding]; other site
1008297009490	ADP-ribose binding site [chemical binding]; other site
1008297009491	active site
1008297009492	nudix motif; other site
1008297009493	metal binding site [ion binding]; metal-binding site
1008297009494	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1008297009495	hypothetical protein; Provisional; Region: PRK11653
1008297009496	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1008297009497	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1008297009498	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1008297009499	putative active site [active]
1008297009500	metal binding site [ion binding]; metal-binding site
1008297009501	zinc transporter ZupT; Provisional; Region: PRK04201
1008297009502	ZIP Zinc transporter; Region: Zip; pfam02535
1008297009503	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1008297009504	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1008297009505	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1008297009506	catalytic residues [active]
1008297009507	hinge region; other site
1008297009508	alpha helical domain; other site
1008297009509	putative disulfide oxidoreductase; Provisional; Region: PRK04307
1008297009510	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1008297009511	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1008297009512	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1008297009513	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
1008297009514	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
1008297009515	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1008297009516	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1008297009517	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1008297009518	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1008297009519	putative ribose interaction site [chemical binding]; other site
1008297009520	putative ADP binding site [chemical binding]; other site
1008297009521	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1008297009522	active site
1008297009523	nucleotide binding site [chemical binding]; other site
1008297009524	HIGH motif; other site
1008297009525	KMSKS motif; other site
1008297009526	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1008297009527	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1008297009528	metal binding triad; other site
1008297009529	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1008297009530	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1008297009531	metal binding triad; other site
1008297009532	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1008297009533	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1008297009534	CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases; Region: CYTH-like_Pase; cl11964
1008297009535	putative metal binding residues [ion binding]; other site
1008297009536	CHAD domain; Region: CHAD; cl10506
1008297009537	CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases; Region: CYTH-like_Pase; cl11964
1008297009538	putative active site; other site
1008297009539	signature motif; other site
1008297009540	putative triphosphate binding site [ion binding]; other site
1008297009541	SH3 domain-containing protein; Provisional; Region: PRK10884
1008297009542	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1008297009543	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1008297009544	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1008297009545	active site
1008297009546	NTP binding site [chemical binding]; other site
1008297009547	metal binding triad [ion binding]; metal-binding site
1008297009548	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1008297009549	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1008297009550	Zn2+ binding site [ion binding]; other site
1008297009551	Mg2+ binding site [ion binding]; other site
1008297009552	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1008297009553	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1008297009554	homooctamer interface [polypeptide binding]; other site
1008297009555	active site
1008297009556	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1008297009557	UGMP family protein; Validated; Region: PRK09604
1008297009558	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1008297009559	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1008297009560	DNA primase; Validated; Region: dnaG; PRK05667
1008297009561	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1008297009562	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1008297009563	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1008297009564	active site
1008297009565	metal binding site [ion binding]; metal-binding site
1008297009566	interdomain interaction site; other site
1008297009567	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1008297009568	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1008297009569	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1008297009570	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1008297009571	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1008297009572	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1008297009573	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1008297009574	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1008297009575	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1008297009576	DNA binding residues [nucleotide binding]
1008297009577	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1008297009578	active site
1008297009579	SUMO-1 interface [polypeptide binding]; other site
1008297009580	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1008297009581	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1008297009582	FAD binding pocket [chemical binding]; other site
1008297009583	FAD binding motif [chemical binding]; other site
1008297009584	phosphate binding motif [ion binding]; other site
1008297009585	NAD binding pocket [chemical binding]; other site
1008297009586	Predicted transcriptional regulators [Transcription]; Region: COG1695
1008297009587	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1008297009588	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1008297009589	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297009590	dimerization interface [polypeptide binding]; other site
1008297009591	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1008297009592	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1008297009593	dimer interface [polypeptide binding]; other site
1008297009594	putative CheW interface [polypeptide binding]; other site
1008297009595	PAS fold; Region: PAS_3; pfam08447
1008297009596	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1008297009597	putative active site [active]
1008297009598	heme pocket [chemical binding]; other site
1008297009599	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1008297009600	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1008297009601	dimer interface [polypeptide binding]; other site
1008297009602	putative CheW interface [polypeptide binding]; other site
1008297009603	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
1008297009604	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1008297009605	inhibitor-cofactor binding pocket; inhibition site
1008297009606	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297009607	catalytic residue [active]
1008297009608	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1008297009609	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1008297009610	active site
1008297009611	FMN binding site [chemical binding]; other site
1008297009612	2,4-decadienoyl-CoA binding site; other site
1008297009613	catalytic residue [active]
1008297009614	4Fe-4S cluster binding site [ion binding]; other site
1008297009615	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1008297009616	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1008297009617	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1008297009618	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297009619	S-adenosylmethionine binding site [chemical binding]; other site
1008297009620	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1008297009621	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1008297009622	putative active site [active]
1008297009623	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1008297009624	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1008297009625	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1008297009626	serine/threonine transporter SstT; Provisional; Region: PRK13628
1008297009627	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1008297009628	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1008297009629	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1008297009630	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1008297009631	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1008297009632	Predicted membrane protein [Function unknown]; Region: COG5393
1008297009633	YqjK-like protein; Region: YqjK; pfam13997
1008297009634	Predicted membrane protein [Function unknown]; Region: COG2259
1008297009635	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1008297009636	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1008297009637	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1008297009638	putative dimer interface [polypeptide binding]; other site
1008297009639	N-terminal domain interface [polypeptide binding]; other site
1008297009640	putative substrate binding pocket (H-site) [chemical binding]; other site
1008297009641	Predicted membrane protein [Function unknown]; Region: COG3152
1008297009642	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297009643	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1008297009644	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1008297009645	dimerization interface [polypeptide binding]; other site
1008297009646	Pirin-related protein [General function prediction only]; Region: COG1741
1008297009647	Pirin; Region: Pirin; pfam02678
1008297009648	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1008297009649	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1008297009650	serine transporter; Region: stp; TIGR00814
1008297009651	L-serine dehydratase TdcG; Provisional; Region: PRK15040
1008297009652	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1008297009653	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1008297009654	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1008297009655	Pyruvate formate lyase 1; Region: PFL1; cd01678
1008297009656	coenzyme A binding site [chemical binding]; other site
1008297009657	active site
1008297009658	catalytic residues [active]
1008297009659	glycine loop; other site
1008297009660	propionate/acetate kinase; Provisional; Region: PRK12379
1008297009661	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
1008297009662	threonine/serine transporter TdcC; Provisional; Region: PRK13629
1008297009663	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1008297009664	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1008297009665	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1008297009666	tetramer interface [polypeptide binding]; other site
1008297009667	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297009668	catalytic residue [active]
1008297009669	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1008297009670	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297009671	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1008297009672	putative substrate binding pocket [chemical binding]; other site
1008297009673	putative dimerization interface [polypeptide binding]; other site
1008297009674	glycerate kinase I; Provisional; Region: PRK10342
1008297009675	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1008297009676	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1008297009677	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1008297009678	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1008297009679	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1008297009680	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1008297009681	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297009682	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1008297009683	substrate binding site [chemical binding]; other site
1008297009684	ATP binding site [chemical binding]; other site
1008297009685	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1008297009686	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1008297009687	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297009688	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1008297009689	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1008297009690	intersubunit interface [polypeptide binding]; other site
1008297009691	active site
1008297009692	zinc binding site [ion binding]; other site
1008297009693	Na+ binding site [ion binding]; other site
1008297009694	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1008297009695	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1008297009696	putative substrate binding site [chemical binding]; other site
1008297009697	putative ATP binding site [chemical binding]; other site
1008297009698	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1008297009699	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1008297009700	active site
1008297009701	P-loop; other site
1008297009702	phosphorylation site [posttranslational modification]
1008297009703	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1008297009704	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297009705	active site
1008297009706	phosphorylation site [posttranslational modification]
1008297009707	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1008297009708	dimerization domain swap beta strand [polypeptide binding]; other site
1008297009709	regulatory protein interface [polypeptide binding]; other site
1008297009710	active site
1008297009711	regulatory phosphorylation site [posttranslational modification]; other site
1008297009712	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
1008297009713	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297009714	active site
1008297009715	phosphorylation site [posttranslational modification]
1008297009716	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1008297009717	active site
1008297009718	P-loop; other site
1008297009719	phosphorylation site [posttranslational modification]
1008297009720	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1008297009721	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1008297009722	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1008297009723	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1008297009724	putative NAD(P) binding site [chemical binding]; other site
1008297009725	catalytic Zn binding site [ion binding]; other site
1008297009726	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1008297009727	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1008297009728	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297009729	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1008297009730	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1008297009731	putative SAM binding site [chemical binding]; other site
1008297009732	putative homodimer interface [polypeptide binding]; other site
1008297009733	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1008297009734	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
1008297009735	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1008297009736	putative ligand binding site [chemical binding]; other site
1008297009737	TIGR00252 family protein; Region: TIGR00252
1008297009738	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1008297009739	dimer interface [polypeptide binding]; other site
1008297009740	active site
1008297009741	outer membrane lipoprotein; Provisional; Region: PRK11023
1008297009742	BON domain; Region: BON; pfam04972
1008297009743	BON domain; Region: BON; pfam04972
1008297009744	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1008297009745	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1008297009746	NAD binding site [chemical binding]; other site
1008297009747	active site
1008297009748	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1008297009749	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1008297009750	proposed catalytic triad [active]
1008297009751	conserved cys residue [active]
1008297009752	hypothetical protein; Provisional; Region: PRK03467
1008297009753	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1008297009754	GIY-YIG motif/motif A; other site
1008297009755	putative active site [active]
1008297009756	putative metal binding site [ion binding]; other site
1008297009757	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1008297009758	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297009759	Coenzyme A binding pocket [chemical binding]; other site
1008297009760	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1008297009761	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1008297009762	Peptidase family U32; Region: Peptidase_U32; pfam01136
1008297009763	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1008297009764	putative protease; Provisional; Region: PRK15447
1008297009765	hypothetical protein; Provisional; Region: PRK10508
1008297009766	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1008297009767	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1008297009768	tryptophan permease; Provisional; Region: PRK10483
1008297009769	aromatic amino acid transport protein; Region: araaP; TIGR00837
1008297009770	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1008297009771	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1008297009772	ATP binding site [chemical binding]; other site
1008297009773	Mg++ binding site [ion binding]; other site
1008297009774	motif III; other site
1008297009775	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297009776	nucleotide binding region [chemical binding]; other site
1008297009777	ATP-binding site [chemical binding]; other site
1008297009778	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1008297009779	putative RNA binding site [nucleotide binding]; other site
1008297009780	lipoprotein NlpI; Provisional; Region: PRK11189
1008297009781	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1008297009782	binding surface
1008297009783	TPR motif; other site
1008297009784	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1008297009785	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1008297009786	RNase E interface [polypeptide binding]; other site
1008297009787	trimer interface [polypeptide binding]; other site
1008297009788	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1008297009789	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1008297009790	RNase E interface [polypeptide binding]; other site
1008297009791	trimer interface [polypeptide binding]; other site
1008297009792	active site
1008297009793	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1008297009794	putative nucleic acid binding region [nucleotide binding]; other site
1008297009795	G-X-X-G motif; other site
1008297009796	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1008297009797	RNA binding site [nucleotide binding]; other site
1008297009798	domain interface; other site
1008297009799	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1008297009800	25S rRNA binding site [nucleotide binding]; other site
1008297009801	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1008297009802	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1008297009803	RNA binding site [nucleotide binding]; other site
1008297009804	active site
1008297009805	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1008297009806	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1008297009807	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1008297009808	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1008297009809	translation initiation factor IF-2; Region: IF-2; TIGR00487
1008297009810	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1008297009811	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1008297009812	G1 box; other site
1008297009813	putative GEF interaction site [polypeptide binding]; other site
1008297009814	GTP/Mg2+ binding site [chemical binding]; other site
1008297009815	Switch I region; other site
1008297009816	G2 box; other site
1008297009817	G3 box; other site
1008297009818	Switch II region; other site
1008297009819	G4 box; other site
1008297009820	G5 box; other site
1008297009821	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1008297009822	Translation-initiation factor 2; Region: IF-2; pfam11987
1008297009823	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1008297009824	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1008297009825	NusA N-terminal domain; Region: NusA_N; pfam08529
1008297009826	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1008297009827	RNA binding site [nucleotide binding]; other site
1008297009828	homodimer interface [polypeptide binding]; other site
1008297009829	NusA-like KH domain; Region: KH_5; pfam13184
1008297009830	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1008297009831	G-X-X-G motif; other site
1008297009832	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1008297009833	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1008297009834	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1008297009835	hypothetical protein; Provisional; Region: PRK14641
1008297009836	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1008297009837	putative oligomer interface [polypeptide binding]; other site
1008297009838	putative RNA binding site [nucleotide binding]; other site
1008297009839	argininosuccinate synthase; Validated; Region: PRK05370
1008297009840	argininosuccinate synthase; Provisional; Region: PRK13820
1008297009841	Domain of unknown function (DUF1963); Region: DUF1963; cl01600
1008297009842	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1008297009843	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1008297009844	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1008297009845	active site
1008297009846	substrate binding site [chemical binding]; other site
1008297009847	metal binding site [ion binding]; metal-binding site
1008297009848	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1008297009849	dihydropteroate synthase; Region: DHPS; TIGR01496
1008297009850	substrate binding pocket [chemical binding]; other site
1008297009851	dimer interface [polypeptide binding]; other site
1008297009852	inhibitor binding site; inhibition site
1008297009853	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1008297009854	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1008297009855	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297009856	Walker A motif; other site
1008297009857	ATP binding site [chemical binding]; other site
1008297009858	Walker B motif; other site
1008297009859	arginine finger; other site
1008297009860	Peptidase family M41; Region: Peptidase_M41; pfam01434
1008297009861	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1008297009862	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297009863	S-adenosylmethionine binding site [chemical binding]; other site
1008297009864	RNA-binding protein YhbY; Provisional; Region: PRK10343
1008297009865	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1008297009866	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1008297009867	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1008297009868	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1008297009869	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1008297009870	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1008297009871	GTP1/OBG; Region: GTP1_OBG; pfam01018
1008297009872	Obg GTPase; Region: Obg; cd01898
1008297009873	G1 box; other site
1008297009874	GTP/Mg2+ binding site [chemical binding]; other site
1008297009875	Switch I region; other site
1008297009876	G2 box; other site
1008297009877	G3 box; other site
1008297009878	Switch II region; other site
1008297009879	G4 box; other site
1008297009880	G5 box; other site
1008297009881	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1008297009882	EamA-like transporter family; Region: EamA; pfam00892
1008297009883	EamA-like transporter family; Region: EamA; pfam00892
1008297009884	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1008297009885	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1008297009886	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1008297009887	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1008297009888	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1008297009889	substrate binding pocket [chemical binding]; other site
1008297009890	chain length determination region; other site
1008297009891	substrate-Mg2+ binding site; other site
1008297009892	catalytic residues [active]
1008297009893	aspartate-rich region 1; other site
1008297009894	active site lid residues [active]
1008297009895	aspartate-rich region 2; other site
1008297009896	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1008297009897	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1008297009898	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1008297009899	hinge; other site
1008297009900	active site
1008297009901	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1008297009902	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1008297009903	anti sigma factor interaction site; other site
1008297009904	regulatory phosphorylation site [posttranslational modification]; other site
1008297009905	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1008297009906	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1008297009907	mce related protein; Region: MCE; pfam02470
1008297009908	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1008297009909	conserved hypothetical integral membrane protein; Region: TIGR00056
1008297009910	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1008297009911	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1008297009912	Walker A/P-loop; other site
1008297009913	ATP binding site [chemical binding]; other site
1008297009914	Q-loop/lid; other site
1008297009915	ABC transporter signature motif; other site
1008297009916	Walker B; other site
1008297009917	D-loop; other site
1008297009918	H-loop/switch region; other site
1008297009919	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1008297009920	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1008297009921	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1008297009922	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1008297009923	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1008297009924	putative active site [active]
1008297009925	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1008297009926	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1008297009927	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1008297009928	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1008297009929	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1008297009930	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1008297009931	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
1008297009932	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1008297009933	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1008297009934	Walker A/P-loop; other site
1008297009935	ATP binding site [chemical binding]; other site
1008297009936	Q-loop/lid; other site
1008297009937	ABC transporter signature motif; other site
1008297009938	Walker B; other site
1008297009939	D-loop; other site
1008297009940	H-loop/switch region; other site
1008297009941	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1008297009942	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1008297009943	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1008297009944	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1008297009945	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1008297009946	30S subunit binding site; other site
1008297009947	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297009948	active site
1008297009949	phosphorylation site [posttranslational modification]
1008297009950	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
1008297009951	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1008297009952	dimerization domain swap beta strand [polypeptide binding]; other site
1008297009953	regulatory protein interface [polypeptide binding]; other site
1008297009954	active site
1008297009955	regulatory phosphorylation site [posttranslational modification]; other site
1008297009956	hypothetical protein; Provisional; Region: PRK10345
1008297009957	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1008297009958	Transglycosylase; Region: Transgly; cl17702
1008297009959	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1008297009960	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1008297009961	conserved cys residue [active]
1008297009962	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1008297009963	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1008297009964	putative active site [active]
1008297009965	heme pocket [chemical binding]; other site
1008297009966	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297009967	dimer interface [polypeptide binding]; other site
1008297009968	phosphorylation site [posttranslational modification]
1008297009969	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297009970	ATP binding site [chemical binding]; other site
1008297009971	Mg2+ binding site [ion binding]; other site
1008297009972	G-X-G motif; other site
1008297009973	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297009974	active site
1008297009975	phosphorylation site [posttranslational modification]
1008297009976	intermolecular recognition site; other site
1008297009977	dimerization interface [polypeptide binding]; other site
1008297009978	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1008297009979	putative binding surface; other site
1008297009980	active site
1008297009981	radical SAM protein, TIGR01212 family; Region: TIGR01212
1008297009982	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297009983	FeS/SAM binding site; other site
1008297009984	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1008297009985	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1008297009986	active site
1008297009987	dimer interface [polypeptide binding]; other site
1008297009988	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1008297009989	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1008297009990	active site
1008297009991	FMN binding site [chemical binding]; other site
1008297009992	substrate binding site [chemical binding]; other site
1008297009993	3Fe-4S cluster binding site [ion binding]; other site
1008297009994	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1008297009995	domain interface; other site
1008297009996	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1008297009997	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1008297009998	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297009999	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1008297010000	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1008297010001	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1008297010002	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1008297010003	Na binding site [ion binding]; other site
1008297010004	putative substrate binding site [chemical binding]; other site
1008297010005	cytosine deaminase; Provisional; Region: PRK09230
1008297010006	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1008297010007	active site
1008297010008	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1008297010009	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1008297010010	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1008297010011	nucleotide binding site [chemical binding]; other site
1008297010012	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1008297010013	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1008297010014	putative active site cavity [active]
1008297010015	putative sialic acid transporter; Provisional; Region: PRK03893
1008297010016	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297010017	putative substrate translocation pore; other site
1008297010018	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1008297010019	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1008297010020	inhibitor site; inhibition site
1008297010021	active site
1008297010022	dimer interface [polypeptide binding]; other site
1008297010023	catalytic residue [active]
1008297010024	transcriptional regulator NanR; Provisional; Region: PRK03837
1008297010025	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297010026	DNA-binding site [nucleotide binding]; DNA binding site
1008297010027	FCD domain; Region: FCD; pfam07729
1008297010028	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
1008297010029	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1008297010030	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1008297010031	C-terminal domain interface [polypeptide binding]; other site
1008297010032	putative GSH binding site (G-site) [chemical binding]; other site
1008297010033	dimer interface [polypeptide binding]; other site
1008297010034	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1008297010035	dimer interface [polypeptide binding]; other site
1008297010036	N-terminal domain interface [polypeptide binding]; other site
1008297010037	Family of unknown function (DUF695); Region: DUF695; pfam05117
1008297010038	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
1008297010039	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1008297010040	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1008297010041	23S rRNA interface [nucleotide binding]; other site
1008297010042	L3 interface [polypeptide binding]; other site
1008297010043	Predicted ATPase [General function prediction only]; Region: COG1485
1008297010044	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1008297010045	hypothetical protein; Provisional; Region: PRK11677
1008297010046	serine endoprotease; Provisional; Region: PRK10139
1008297010047	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1008297010048	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1008297010049	protein binding site [polypeptide binding]; other site
1008297010050	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1008297010051	serine endoprotease; Provisional; Region: PRK10898
1008297010052	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1008297010053	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1008297010054	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1008297010055	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1008297010056	oxaloacetate decarboxylase alpha chain
1008297010057	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1008297010058	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
1008297010059	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
1008297010060	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1008297010061	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1008297010062	transmembrane helices; other site
1008297010063	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1008297010064	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297010065	DNA-binding site [nucleotide binding]; DNA binding site
1008297010066	FCD domain; Region: FCD; pfam07729
1008297010067	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1008297010068	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297010069	DNA-binding site [nucleotide binding]; DNA binding site
1008297010070	malate dehydrogenase; Provisional; Region: PRK05086
1008297010071	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1008297010072	NAD binding site [chemical binding]; other site
1008297010073	dimerization interface [polypeptide binding]; other site
1008297010074	Substrate binding site [chemical binding]; other site
1008297010075	arginine repressor; Provisional; Region: PRK05066
1008297010076	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1008297010077	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1008297010078	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1008297010079	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1008297010080	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1008297010081	RNAase interaction site [polypeptide binding]; other site
1008297010082	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1008297010083	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1008297010084	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1008297010085	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1008297010086	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297010087	efflux system membrane protein; Provisional; Region: PRK11594
1008297010088	transcriptional regulator; Provisional; Region: PRK10632
1008297010089	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297010090	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1008297010091	putative effector binding pocket; other site
1008297010092	dimerization interface [polypeptide binding]; other site
1008297010093	protease TldD; Provisional; Region: tldD; PRK10735
1008297010094	hypothetical protein; Provisional; Region: PRK10899
1008297010095	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1008297010096	ribonuclease G; Provisional; Region: PRK11712
1008297010097	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1008297010098	homodimer interface [polypeptide binding]; other site
1008297010099	oligonucleotide binding site [chemical binding]; other site
1008297010100	Maf-like protein; Region: Maf; pfam02545
1008297010101	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1008297010102	active site
1008297010103	dimer interface [polypeptide binding]; other site
1008297010104	rod shape-determining protein MreD; Provisional; Region: PRK11060
1008297010105	rod shape-determining protein MreC; Region: mreC; TIGR00219
1008297010106	rod shape-determining protein MreC; Region: MreC; pfam04085
1008297010107	rod shape-determining protein MreB; Provisional; Region: PRK13927
1008297010108	MreB and similar proteins; Region: MreB_like; cd10225
1008297010109	nucleotide binding site [chemical binding]; other site
1008297010110	Mg binding site [ion binding]; other site
1008297010111	putative protofilament interaction site [polypeptide binding]; other site
1008297010112	RodZ interaction site [polypeptide binding]; other site
1008297010113	regulatory protein CsrD; Provisional; Region: PRK11059
1008297010114	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1008297010115	metal binding site [ion binding]; metal-binding site
1008297010116	active site
1008297010117	I-site; other site
1008297010118	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297010119	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1008297010120	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1008297010121	NADP binding site [chemical binding]; other site
1008297010122	dimer interface [polypeptide binding]; other site
1008297010123	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1008297010124	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1008297010125	Moco binding site; other site
1008297010126	metal coordination site [ion binding]; other site
1008297010127	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1008297010128	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1008297010129	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1008297010130	carboxyltransferase (CT) interaction site; other site
1008297010131	biotinylation site [posttranslational modification]; other site
1008297010132	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1008297010133	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1008297010134	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1008297010135	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1008297010136	hypothetical protein; Provisional; Region: PRK10633
1008297010137	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1008297010138	Na binding site [ion binding]; other site
1008297010139	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
1008297010140	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1008297010141	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
1008297010142	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1008297010143	FMN binding site [chemical binding]; other site
1008297010144	active site
1008297010145	catalytic residues [active]
1008297010146	substrate binding site [chemical binding]; other site
1008297010147	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1008297010148	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1008297010149	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1008297010150	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297010151	DNA methylase; Region: N6_N4_Mtase; pfam01555
1008297010152	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
1008297010153	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1008297010154	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1008297010155	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1008297010156	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1008297010157	metal binding site [ion binding]; metal-binding site
1008297010158	active site
1008297010159	I-site; other site
1008297010160	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297010161	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
1008297010162	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297010163	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1008297010164	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1008297010165	HlyD family secretion protein; Region: HlyD; pfam00529
1008297010166	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297010167	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1008297010168	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1008297010169	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1008297010170	trimer interface [polypeptide binding]; other site
1008297010171	putative metal binding site [ion binding]; other site
1008297010172	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1008297010173	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1008297010174	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1008297010175	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1008297010176	shikimate binding site; other site
1008297010177	NAD(P) binding site [chemical binding]; other site
1008297010178	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1008297010179	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1008297010180	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1008297010181	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1008297010182	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1008297010183	hypothetical protein; Validated; Region: PRK03430
1008297010184	hypothetical protein; Provisional; Region: PRK10736
1008297010185	DNA protecting protein DprA; Region: dprA; TIGR00732
1008297010186	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1008297010187	active site
1008297010188	catalytic residues [active]
1008297010189	metal binding site [ion binding]; metal-binding site
1008297010190	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1008297010191	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1008297010192	putative active site [active]
1008297010193	substrate binding site [chemical binding]; other site
1008297010194	putative cosubstrate binding site; other site
1008297010195	catalytic site [active]
1008297010196	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1008297010197	substrate binding site [chemical binding]; other site
1008297010198	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1008297010199	putative RNA binding site [nucleotide binding]; other site
1008297010200	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1008297010201	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297010202	S-adenosylmethionine binding site [chemical binding]; other site
1008297010203	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1008297010204	TrkA-N domain; Region: TrkA_N; pfam02254
1008297010205	TrkA-C domain; Region: TrkA_C; pfam02080
1008297010206	TrkA-N domain; Region: TrkA_N; pfam02254
1008297010207	TrkA-C domain; Region: TrkA_C; pfam02080
1008297010208	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1008297010209	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1008297010210	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1008297010211	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1008297010212	DNA binding residues [nucleotide binding]
1008297010213	dimer interface [polypeptide binding]; other site
1008297010214	metal binding site [ion binding]; metal-binding site
1008297010215	hypothetical protein; Provisional; Region: PRK10203
1008297010216	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1008297010217	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1008297010218	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1008297010219	alphaNTD homodimer interface [polypeptide binding]; other site
1008297010220	alphaNTD - beta interaction site [polypeptide binding]; other site
1008297010221	alphaNTD - beta' interaction site [polypeptide binding]; other site
1008297010222	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1008297010223	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1008297010224	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1008297010225	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1008297010226	RNA binding surface [nucleotide binding]; other site
1008297010227	30S ribosomal protein S11; Validated; Region: PRK05309
1008297010228	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1008297010229	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1008297010230	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1008297010231	SecY translocase; Region: SecY; pfam00344
1008297010232	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1008297010233	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1008297010234	23S rRNA binding site [nucleotide binding]; other site
1008297010235	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1008297010236	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1008297010237	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1008297010238	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1008297010239	23S rRNA interface [nucleotide binding]; other site
1008297010240	5S rRNA interface [nucleotide binding]; other site
1008297010241	L27 interface [polypeptide binding]; other site
1008297010242	L5 interface [polypeptide binding]; other site
1008297010243	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1008297010244	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1008297010245	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1008297010246	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1008297010247	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1008297010248	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1008297010249	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1008297010250	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1008297010251	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1008297010252	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1008297010253	RNA binding site [nucleotide binding]; other site
1008297010254	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1008297010255	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1008297010256	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1008297010257	23S rRNA interface [nucleotide binding]; other site
1008297010258	putative translocon interaction site; other site
1008297010259	signal recognition particle (SRP54) interaction site; other site
1008297010260	L23 interface [polypeptide binding]; other site
1008297010261	trigger factor interaction site; other site
1008297010262	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1008297010263	23S rRNA interface [nucleotide binding]; other site
1008297010264	5S rRNA interface [nucleotide binding]; other site
1008297010265	putative antibiotic binding site [chemical binding]; other site
1008297010266	L25 interface [polypeptide binding]; other site
1008297010267	L27 interface [polypeptide binding]; other site
1008297010268	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1008297010269	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1008297010270	G-X-X-G motif; other site
1008297010271	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1008297010272	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1008297010273	protein-rRNA interface [nucleotide binding]; other site
1008297010274	putative translocon binding site; other site
1008297010275	Ribosomal protein S19; Region: Ribosomal_S19; cl00350
1008297010276	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1008297010277	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1008297010278	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1008297010279	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1008297010280	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1008297010281	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1008297010282	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1008297010283	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1008297010284	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1008297010285	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1008297010286	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1008297010287	heme binding site [chemical binding]; other site
1008297010288	ferroxidase pore; other site
1008297010289	ferroxidase diiron center [ion binding]; other site
1008297010290	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1008297010291	elongation factor Tu; Reviewed; Region: PRK00049
1008297010292	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1008297010293	G1 box; other site
1008297010294	GEF interaction site [polypeptide binding]; other site
1008297010295	GTP/Mg2+ binding site [chemical binding]; other site
1008297010296	Switch I region; other site
1008297010297	G2 box; other site
1008297010298	G3 box; other site
1008297010299	Switch II region; other site
1008297010300	G4 box; other site
1008297010301	G5 box; other site
1008297010302	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1008297010303	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1008297010304	Antibiotic Binding Site [chemical binding]; other site
1008297010305	elongation factor G; Reviewed; Region: PRK00007
1008297010306	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1008297010307	G1 box; other site
1008297010308	putative GEF interaction site [polypeptide binding]; other site
1008297010309	GTP/Mg2+ binding site [chemical binding]; other site
1008297010310	Switch I region; other site
1008297010311	G2 box; other site
1008297010312	G3 box; other site
1008297010313	Switch II region; other site
1008297010314	G4 box; other site
1008297010315	G5 box; other site
1008297010316	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1008297010317	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1008297010318	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1008297010319	30S ribosomal protein S7; Validated; Region: PRK05302
1008297010320	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1008297010321	16S rRNA interaction site [nucleotide binding]; other site
1008297010322	streptomycin interaction site [chemical binding]; other site
1008297010323	23S rRNA interaction site [nucleotide binding]; other site
1008297010324	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1008297010325	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1008297010326	sulfur relay protein TusC; Validated; Region: PRK00211
1008297010327	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1008297010328	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1008297010329	YheO-like PAS domain; Region: PAS_6; pfam08348
1008297010330	HTH domain; Region: HTH_22; pfam13309
1008297010331	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1008297010332	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1008297010333	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1008297010334	phi X174 lysis protein; Provisional; Region: PRK02793
1008297010335	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1008297010336	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1008297010337	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1008297010338	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1008297010339	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1008297010340	TrkA-N domain; Region: TrkA_N; pfam02254
1008297010341	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1008297010342	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1008297010343	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297010344	Walker A/P-loop; other site
1008297010345	ATP binding site [chemical binding]; other site
1008297010346	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1008297010347	ABC transporter signature motif; other site
1008297010348	Walker B; other site
1008297010349	D-loop; other site
1008297010350	ABC transporter; Region: ABC_tran_2; pfam12848
1008297010351	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1008297010352	putative monooxygenase; Provisional; Region: PRK11118
1008297010353	putative hydrolase; Provisional; Region: PRK10985
1008297010354	hypothetical protein; Provisional; Region: PRK04966
1008297010355	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1008297010356	active site
1008297010357	OsmC-like protein; Region: OsmC; cl00767
1008297010358	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1008297010359	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1008297010360	ligand binding site [chemical binding]; other site
1008297010361	flexible hinge region; other site
1008297010362	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1008297010363	putative switch regulator; other site
1008297010364	non-specific DNA interactions [nucleotide binding]; other site
1008297010365	DNA binding site [nucleotide binding]
1008297010366	sequence specific DNA binding site [nucleotide binding]; other site
1008297010367	putative cAMP binding site [chemical binding]; other site
1008297010368	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1008297010369	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1008297010370	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1008297010371	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1008297010372	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1008297010373	inhibitor-cofactor binding pocket; inhibition site
1008297010374	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297010375	catalytic residue [active]
1008297010376	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1008297010377	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1008297010378	glutamine binding [chemical binding]; other site
1008297010379	catalytic triad [active]
1008297010380	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1008297010381	cell filamentation protein Fic; Provisional; Region: PRK10347
1008297010382	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1008297010383	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1008297010384	substrate binding site [chemical binding]; other site
1008297010385	putative transporter; Provisional; Region: PRK03699
1008297010386	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297010387	putative substrate translocation pore; other site
1008297010388	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1008297010389	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297010390	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1008297010391	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1008297010392	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1008297010393	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1008297010394	nitrite transporter NirC; Provisional; Region: PRK11562
1008297010395	siroheme synthase; Provisional; Region: cysG; PRK10637
1008297010396	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1008297010397	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1008297010398	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1008297010399	active site
1008297010400	SAM binding site [chemical binding]; other site
1008297010401	homodimer interface [polypeptide binding]; other site
1008297010402	putative surface-exposed virulence protein BigA
1008297010403	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1008297010404	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1008297010405	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1008297010406	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1008297010407	active site
1008297010408	HIGH motif; other site
1008297010409	dimer interface [polypeptide binding]; other site
1008297010410	KMSKS motif; other site
1008297010411	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1008297010412	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297010413	motif II; other site
1008297010414	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1008297010415	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1008297010416	substrate binding site [chemical binding]; other site
1008297010417	hexamer interface [polypeptide binding]; other site
1008297010418	metal binding site [ion binding]; metal-binding site
1008297010419	DNA adenine methylase; Provisional; Region: PRK10904
1008297010420	cell division protein DamX; Validated; Region: PRK10905
1008297010421	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
1008297010422	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1008297010423	active site
1008297010424	dimer interface [polypeptide binding]; other site
1008297010425	metal binding site [ion binding]; metal-binding site
1008297010426	shikimate kinase; Reviewed; Region: aroK; PRK00131
1008297010427	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1008297010428	ADP binding site [chemical binding]; other site
1008297010429	magnesium binding site [ion binding]; other site
1008297010430	putative shikimate binding site; other site
1008297010431	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1008297010432	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1008297010433	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
1008297010434	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1008297010435	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1008297010436	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1008297010437	Transglycosylase; Region: Transgly; pfam00912
1008297010438	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1008297010439	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1008297010440	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1008297010441	ADP-ribose binding site [chemical binding]; other site
1008297010442	dimer interface [polypeptide binding]; other site
1008297010443	active site
1008297010444	nudix motif; other site
1008297010445	metal binding site [ion binding]; metal-binding site
1008297010446	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1008297010447	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1008297010448	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297010449	motif II; other site
1008297010450	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1008297010451	RNA binding surface [nucleotide binding]; other site
1008297010452	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1008297010453	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1008297010454	dimerization interface [polypeptide binding]; other site
1008297010455	domain crossover interface; other site
1008297010456	redox-dependent activation switch; other site
1008297010457	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1008297010458	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1008297010459	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1008297010460	active site
1008297010461	substrate-binding site [chemical binding]; other site
1008297010462	metal-binding site [ion binding]
1008297010463	ATP binding site [chemical binding]; other site
1008297010464	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1008297010465	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297010466	dimerization interface [polypeptide binding]; other site
1008297010467	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297010468	dimer interface [polypeptide binding]; other site
1008297010469	phosphorylation site [posttranslational modification]
1008297010470	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297010471	ATP binding site [chemical binding]; other site
1008297010472	G-X-G motif; other site
1008297010473	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1008297010474	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297010475	active site
1008297010476	phosphorylation site [posttranslational modification]
1008297010477	intermolecular recognition site; other site
1008297010478	dimerization interface [polypeptide binding]; other site
1008297010479	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297010480	DNA binding site [nucleotide binding]
1008297010481	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1008297010482	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1008297010483	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1008297010484	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1008297010485	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1008297010486	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1008297010487	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1008297010488	RNA binding site [nucleotide binding]; other site
1008297010489	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1008297010490	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1008297010491	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1008297010492	G1 box; other site
1008297010493	GTP/Mg2+ binding site [chemical binding]; other site
1008297010494	Switch I region; other site
1008297010495	G2 box; other site
1008297010496	G3 box; other site
1008297010497	Switch II region; other site
1008297010498	G4 box; other site
1008297010499	G5 box; other site
1008297010500	Nucleoside recognition; Region: Gate; pfam07670
1008297010501	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1008297010502	Nucleoside recognition; Region: Gate; pfam07670
1008297010503	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1008297010504	hypothetical protein; Provisional; Region: PRK09956
1008297010505	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1008297010506	carboxylesterase BioH; Provisional; Region: PRK10349
1008297010507	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1008297010508	DNA utilization protein GntX; Provisional; Region: PRK11595
1008297010509	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1008297010510	active site
1008297010511	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1008297010512	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1008297010513	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1008297010514	high-affinity gluconate transporter; Provisional; Region: PRK14984
1008297010515	gluconate transporter; Region: gntP; TIGR00791
1008297010516	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1008297010517	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1008297010518	maltodextrin phosphorylase; Provisional; Region: PRK14985
1008297010519	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1008297010520	homodimer interface [polypeptide binding]; other site
1008297010521	active site pocket [active]
1008297010522	transcriptional regulator MalT; Provisional; Region: PRK04841
1008297010523	AAA ATPase domain; Region: AAA_16; pfam13191
1008297010524	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297010525	DNA binding residues [nucleotide binding]
1008297010526	dimerization interface [polypeptide binding]; other site
1008297010527	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
1008297010528	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
1008297010529	RNA 3' phosphate cyclase domain (class II). These proteins function as RNA cyclase to catalyze the ATP-dependent conversion of 3'-phosphate to a 2'.3'-cyclic phosphodiester at the end of RNA molecule. A conserved catalytic histidine...; Region: RNA_Cyclase_Class_II; cd00874
1008297010530	putative active site [active]
1008297010531	adenylation catalytic residue [active]
1008297010532	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1008297010533	hypothetical protein; Reviewed; Region: PRK09588
1008297010534	hypothetical protein
1008297010535	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
1008297010536	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
1008297010537	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297010538	Walker A motif; other site
1008297010539	ATP binding site [chemical binding]; other site
1008297010540	Walker B motif; other site
1008297010541	arginine finger; other site
1008297010542	putative glycerol-3-phosphate regulon repressor (pseudogene)
1008297010543	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1008297010544	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1008297010545	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1008297010546	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1008297010547	active site residue [active]
1008297010548	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1008297010549	hypothetical protein; Provisional; Region: PRK09781
1008297010550	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
1008297010551	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1008297010552	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1008297010553	active site
1008297010554	metal binding site [ion binding]; metal-binding site
1008297010555	dimer interface [polypeptide binding]; other site
1008297010556	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297010557	D-galactonate transporter; Region: 2A0114; TIGR00893
1008297010558	putative substrate translocation pore; other site
1008297010559	Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism / Carbohydrate transport and metabolism]; Region: IlvD; COG0129
1008297010560	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1008297010561	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1008297010562	inhibitor site; inhibition site
1008297010563	active site
1008297010564	dimer interface [polypeptide binding]; other site
1008297010565	catalytic residue [active]
1008297010566	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1008297010567	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1008297010568	Bacterial transcriptional regulator; Region: IclR; pfam01614
1008297010569	glycogen phosphorylase; Provisional; Region: PRK14986
1008297010570	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1008297010571	homodimer interface [polypeptide binding]; other site
1008297010572	active site pocket [active]
1008297010573	glycogen synthase; Provisional; Region: glgA; PRK00654
1008297010574	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1008297010575	ADP-binding pocket [chemical binding]; other site
1008297010576	homodimer interface [polypeptide binding]; other site
1008297010577	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1008297010578	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1008297010579	ligand binding site; other site
1008297010580	oligomer interface; other site
1008297010581	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1008297010582	dimer interface [polypeptide binding]; other site
1008297010583	N-terminal domain interface [polypeptide binding]; other site
1008297010584	sulfate 1 binding site; other site
1008297010585	glycogen debranching enzyme; Provisional; Region: PRK03705
1008297010586	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1008297010587	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1008297010588	active site
1008297010589	catalytic site [active]
1008297010590	glycogen branching enzyme; Provisional; Region: PRK05402
1008297010591	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1008297010592	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1008297010593	active site
1008297010594	catalytic site [active]
1008297010595	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1008297010596	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1008297010597	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1008297010598	low affinity gluconate transporter; Provisional; Region: PRK10472
1008297010599	gluconate transporter; Region: gntP; TIGR00791
1008297010600	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1008297010601	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1008297010602	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297010603	DNA binding site [nucleotide binding]
1008297010604	domain linker motif; other site
1008297010605	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1008297010606	putative ligand binding site [chemical binding]; other site
1008297010607	putative dimerization interface [polypeptide binding]; other site
1008297010608	Pirin-related protein [General function prediction only]; Region: COG1741
1008297010609	Pirin; Region: Pirin; pfam02678
1008297010610	putative oxidoreductase; Provisional; Region: PRK10206
1008297010611	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1008297010612	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1008297010613	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1008297010614	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297010615	Coenzyme A binding pocket [chemical binding]; other site
1008297010616	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1008297010617	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1008297010618	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297010619	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1008297010620	substrate binding site [chemical binding]; other site
1008297010621	dimer interface [polypeptide binding]; other site
1008297010622	ATP binding site [chemical binding]; other site
1008297010623	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1008297010624	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1008297010625	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1008297010626	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1008297010627	active site
1008297010628	substrate binding pocket [chemical binding]; other site
1008297010629	homodimer interaction site [polypeptide binding]; other site
1008297010630	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1008297010631	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1008297010632	hypothetical protein; Provisional; Region: PRK10350
1008297010633	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1008297010634	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1008297010635	putative active site [active]
1008297010636	catalytic site [active]
1008297010637	putative metal binding site [ion binding]; other site
1008297010638	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1008297010639	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1008297010640	Walker A/P-loop; other site
1008297010641	ATP binding site [chemical binding]; other site
1008297010642	Q-loop/lid; other site
1008297010643	ABC transporter signature motif; other site
1008297010644	Walker B; other site
1008297010645	D-loop; other site
1008297010646	H-loop/switch region; other site
1008297010647	TOBE domain; Region: TOBE_2; pfam08402
1008297010648	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1008297010649	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297010650	dimer interface [polypeptide binding]; other site
1008297010651	conserved gate region; other site
1008297010652	ABC-ATPase subunit interface; other site
1008297010653	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1008297010654	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297010655	dimer interface [polypeptide binding]; other site
1008297010656	conserved gate region; other site
1008297010657	putative PBP binding loops; other site
1008297010658	ABC-ATPase subunit interface; other site
1008297010659	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1008297010660	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1008297010661	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
1008297010662	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1008297010663	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1008297010664	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1008297010665	Walker A/P-loop; other site
1008297010666	ATP binding site [chemical binding]; other site
1008297010667	Q-loop/lid; other site
1008297010668	ABC transporter signature motif; other site
1008297010669	Walker B; other site
1008297010670	D-loop; other site
1008297010671	H-loop/switch region; other site
1008297010672	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1008297010673	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1008297010674	Walker A/P-loop; other site
1008297010675	ATP binding site [chemical binding]; other site
1008297010676	Q-loop/lid; other site
1008297010677	ABC transporter signature motif; other site
1008297010678	Walker B; other site
1008297010679	D-loop; other site
1008297010680	H-loop/switch region; other site
1008297010681	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1008297010682	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1008297010683	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1008297010684	TM-ABC transporter signature motif; other site
1008297010685	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1008297010686	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1008297010687	TM-ABC transporter signature motif; other site
1008297010688	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1008297010689	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1008297010690	dimerization interface [polypeptide binding]; other site
1008297010691	ligand binding site [chemical binding]; other site
1008297010692	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1008297010693	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1008297010694	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1008297010695	dimerization interface [polypeptide binding]; other site
1008297010696	ligand binding site [chemical binding]; other site
1008297010697	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1008297010698	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1008297010699	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1008297010700	DNA binding residues [nucleotide binding]
1008297010701	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1008297010702	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1008297010703	cell division protein FtsE; Provisional; Region: PRK10908
1008297010704	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297010705	Walker A/P-loop; other site
1008297010706	ATP binding site [chemical binding]; other site
1008297010707	Q-loop/lid; other site
1008297010708	ABC transporter signature motif; other site
1008297010709	Walker B; other site
1008297010710	D-loop; other site
1008297010711	H-loop/switch region; other site
1008297010712	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1008297010713	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1008297010714	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1008297010715	P loop; other site
1008297010716	GTP binding site [chemical binding]; other site
1008297010717	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1008297010718	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297010719	S-adenosylmethionine binding site [chemical binding]; other site
1008297010720	hypothetical protein; Provisional; Region: PRK10910
1008297010721	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1008297010722	Predicted membrane protein [Function unknown]; Region: COG3714
1008297010723	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1008297010724	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1008297010725	metal-binding site [ion binding]
1008297010726	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1008297010727	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1008297010728	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1008297010729	dimer interface [polypeptide binding]; other site
1008297010730	ligand binding site [chemical binding]; other site
1008297010731	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297010732	dimerization interface [polypeptide binding]; other site
1008297010733	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1008297010734	dimer interface [polypeptide binding]; other site
1008297010735	putative CheW interface [polypeptide binding]; other site
1008297010736	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1008297010737	CPxP  motif; other site
1008297010738	hypothetical protein; Provisional; Region: PRK11212
1008297010739	hypothetical protein; Provisional; Region: PRK11615
1008297010740	major facilitator superfamily transporter; Provisional; Region: PRK05122
1008297010741	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297010742	putative substrate translocation pore; other site
1008297010743	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1008297010744	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1008297010745	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1008297010746	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1008297010747	nickel responsive regulator; Provisional; Region: PRK02967
1008297010748	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1008297010749	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1008297010750	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1008297010751	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1008297010752	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1008297010753	Walker A/P-loop; other site
1008297010754	ATP binding site [chemical binding]; other site
1008297010755	Q-loop/lid; other site
1008297010756	ABC transporter signature motif; other site
1008297010757	Walker B; other site
1008297010758	D-loop; other site
1008297010759	H-loop/switch region; other site
1008297010760	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1008297010761	Walker A/P-loop; other site
1008297010762	ATP binding site [chemical binding]; other site
1008297010763	Q-loop/lid; other site
1008297010764	ABC transporter signature motif; other site
1008297010765	Walker B; other site
1008297010766	D-loop; other site
1008297010767	H-loop/switch region; other site
1008297010768	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1008297010769	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1008297010770	HlyD family secretion protein; Region: HlyD; pfam00529
1008297010771	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1008297010772	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297010773	Predicted flavoproteins [General function prediction only]; Region: COG2081
1008297010774	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1008297010775	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1008297010776	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1008297010777	universal stress protein UspB; Provisional; Region: PRK04960
1008297010778	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1008297010779	Ligand Binding Site [chemical binding]; other site
1008297010780	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1008297010781	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297010782	putative substrate translocation pore; other site
1008297010783	POT family; Region: PTR2; pfam00854
1008297010784	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297010785	S-adenosylmethionine binding site [chemical binding]; other site
1008297010786	oligopeptidase A; Provisional; Region: PRK10911
1008297010787	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1008297010788	active site
1008297010789	Zn binding site [ion binding]; other site
1008297010790	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1008297010791	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1008297010792	active site
1008297010793	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1008297010794	glutathione reductase; Validated; Region: PRK06116
1008297010795	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1008297010796	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297010797	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1008297010798	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1008297010799	active site
1008297010800	homodimer interface [polypeptide binding]; other site
1008297010801	homotetramer interface [polypeptide binding]; other site
1008297010802	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1008297010803	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1008297010804	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
1008297010805	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297010806	substrate binding site [chemical binding]; other site
1008297010807	ATP binding site [chemical binding]; other site
1008297010808	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1008297010809	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1008297010810	putative active site [active]
1008297010811	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1008297010812	dimer interface [polypeptide binding]; other site
1008297010813	active site
1008297010814	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1008297010815	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297010816	DNA-binding site [nucleotide binding]; DNA binding site
1008297010817	UTRA domain; Region: UTRA; pfam07702
1008297010818	trehalase; Provisional; Region: treF; PRK13270
1008297010819	Trehalase; Region: Trehalase; pfam01204
1008297010820	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
1008297010821	catalytic residue [active]
1008297010822	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1008297010823	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297010824	DNA binding residues [nucleotide binding]
1008297010825	dimerization interface [polypeptide binding]; other site
1008297010826	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297010827	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297010828	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1008297010829	putative effector binding pocket; other site
1008297010830	putative dimerization interface [polypeptide binding]; other site
1008297010831	inner membrane protein YhjD; Region: TIGR00766
1008297010832	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297010833	metabolite-proton symporter; Region: 2A0106; TIGR00883
1008297010834	putative substrate translocation pore; other site
1008297010835	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1008297010836	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1008297010837	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297010838	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297010839	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1008297010840	substrate binding site [chemical binding]; other site
1008297010841	ATP binding site [chemical binding]; other site
1008297010842	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1008297010843	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1008297010844	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1008297010845	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1008297010846	putative diguanylate cyclase; Provisional; Region: PRK13561
1008297010847	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1008297010848	metal binding site [ion binding]; metal-binding site
1008297010849	active site
1008297010850	I-site; other site
1008297010851	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297010852	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1008297010853	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1008297010854	TPR motif; other site
1008297010855	binding surface
1008297010856	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1008297010857	TPR motif; other site
1008297010858	binding surface
1008297010859	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1008297010860	binding surface
1008297010861	TPR motif; other site
1008297010862	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1008297010863	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1008297010864	cellulose synthase regulator protein; Provisional; Region: PRK11114
1008297010865	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1008297010866	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1008297010867	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1008297010868	DXD motif; other site
1008297010869	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1008297010870	PilZ domain; Region: PilZ; pfam07238
1008297010871	cell division protein; Provisional; Region: PRK10037
1008297010872	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1008297010873	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
1008297010874	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
1008297010875	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
1008297010876	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
1008297010877	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1008297010878	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1008297010879	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1008297010880	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1008297010881	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1008297010882	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297010883	Walker A/P-loop; other site
1008297010884	ATP binding site [chemical binding]; other site
1008297010885	Q-loop/lid; other site
1008297010886	ABC transporter signature motif; other site
1008297010887	Walker B; other site
1008297010888	D-loop; other site
1008297010889	H-loop/switch region; other site
1008297010890	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1008297010891	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1008297010892	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1008297010893	Walker A/P-loop; other site
1008297010894	ATP binding site [chemical binding]; other site
1008297010895	Q-loop/lid; other site
1008297010896	ABC transporter signature motif; other site
1008297010897	Walker B; other site
1008297010898	D-loop; other site
1008297010899	H-loop/switch region; other site
1008297010900	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1008297010901	dipeptide transporter; Provisional; Region: PRK10913
1008297010902	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1008297010903	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297010904	dimer interface [polypeptide binding]; other site
1008297010905	conserved gate region; other site
1008297010906	putative PBP binding loops; other site
1008297010907	ABC-ATPase subunit interface; other site
1008297010908	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1008297010909	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297010910	dimer interface [polypeptide binding]; other site
1008297010911	conserved gate region; other site
1008297010912	putative PBP binding loops; other site
1008297010913	ABC-ATPase subunit interface; other site
1008297010914	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1008297010915	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1008297010916	peptide binding site [polypeptide binding]; other site
1008297010917	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1008297010918	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
1008297010919	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1008297010920	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297010921	DNA binding site [nucleotide binding]
1008297010922	domain linker motif; other site
1008297010923	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
1008297010924	putative dimerization interface [polypeptide binding]; other site
1008297010925	putative ligand binding site [chemical binding]; other site
1008297010926	phosphoethanolamine transferase; Provisional; Region: PRK11560
1008297010927	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1008297010928	Sulfatase; Region: Sulfatase; pfam00884
1008297010929	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
1008297010930	fimbrial protein (LpfD) (pseudogene)
1008297010931	potential frameshift: common BLAST hit: gi|379702900|ref|YP_005244628.1| long polar fimbrial outer membrane usher protein
1008297010932	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
1008297010933	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297010934	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297010935	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
1008297010936	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1008297010937	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
1008297010938	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297010939	Coenzyme A binding pocket [chemical binding]; other site
1008297010940	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1008297010941	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1008297010942	molybdopterin cofactor binding site [chemical binding]; other site
1008297010943	substrate binding site [chemical binding]; other site
1008297010944	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1008297010945	molybdopterin cofactor binding site; other site
1008297010946	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1008297010947	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1008297010948	ligand binding site [chemical binding]; other site
1008297010949	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1008297010950	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1008297010951	dimerization interface [polypeptide binding]; other site
1008297010952	ligand binding site [chemical binding]; other site
1008297010953	NADP binding site [chemical binding]; other site
1008297010954	catalytic site [active]
1008297010955	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1008297010956	Predicted transcriptional regulator [Transcription]; Region: COG2944
1008297010957	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1008297010958	salt bridge; other site
1008297010959	non-specific DNA binding site [nucleotide binding]; other site
1008297010960	sequence-specific DNA binding site [nucleotide binding]; other site
1008297010961	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1008297010962	DNA-binding site [nucleotide binding]; DNA binding site
1008297010963	RNA-binding motif; other site
1008297010964	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1008297010965	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1008297010966	DALR anticodon binding domain; Region: DALR_1; pfam05746
1008297010967	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1008297010968	dimer interface [polypeptide binding]; other site
1008297010969	active site
1008297010970	motif 2; other site
1008297010971	motif 3; other site
1008297010972	YsaB-like lipoprotein; Region: YsaB; pfam13983
1008297010973	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1008297010974	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1008297010975	Predicted membrane protein [Function unknown]; Region: COG4682
1008297010976	yiaA/B two helix domain; Region: YiaAB; cl01759
1008297010977	yiaA/B two helix domain; Region: YiaAB; cl01759
1008297010978	xylulokinase; Provisional; Region: PRK15027
1008297010979	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1008297010980	N- and C-terminal domain interface [polypeptide binding]; other site
1008297010981	active site
1008297010982	MgATP binding site [chemical binding]; other site
1008297010983	catalytic site [active]
1008297010984	metal binding site [ion binding]; metal-binding site
1008297010985	xylulose binding site [chemical binding]; other site
1008297010986	homodimer interface [polypeptide binding]; other site
1008297010987	xylose isomerase; Provisional; Region: PRK05474
1008297010988	xylose isomerase; Region: xylose_isom_A; TIGR02630
1008297010989	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1008297010990	putative dimerization interface [polypeptide binding]; other site
1008297010991	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1008297010992	putative ligand binding site [chemical binding]; other site
1008297010993	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297010994	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1008297010995	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297010996	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1008297010997	hypothetical protein; Provisional; Region: PRK10356
1008297010998	alpha-amylase; Reviewed; Region: malS; PRK09505
1008297010999	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1008297011000	active site
1008297011001	catalytic site [active]
1008297011002	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1008297011003	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297011004	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297011005	homodimer interface [polypeptide binding]; other site
1008297011006	catalytic residue [active]
1008297011007	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1008297011008	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1008297011009	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1008297011010	Bacterial transcriptional regulator; Region: IclR; pfam01614
1008297011011	potential frameshift: common BLAST hit: gi|379702929|ref|YP_005244657.1| 2,3-diketo-L-gulonate reductase
1008297011012	Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900
1008297011013	Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900
1008297011014	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1008297011015	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
1008297011016	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
1008297011017	DctM-like transporters; Region: DctM; pfam06808
1008297011018	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1008297011019	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1008297011020	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1008297011021	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1008297011022	putative N- and C-terminal domain interface [polypeptide binding]; other site
1008297011023	putative active site [active]
1008297011024	MgATP binding site [chemical binding]; other site
1008297011025	catalytic site [active]
1008297011026	metal binding site [ion binding]; metal-binding site
1008297011027	putative xylulose binding site [chemical binding]; other site
1008297011028	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1008297011029	active site
1008297011030	dimer interface [polypeptide binding]; other site
1008297011031	magnesium binding site [ion binding]; other site
1008297011032	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1008297011033	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1008297011034	AP (apurinic/apyrimidinic) site pocket; other site
1008297011035	DNA interaction; other site
1008297011036	Metal-binding active site; metal-binding site
1008297011037	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1008297011038	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1008297011039	intersubunit interface [polypeptide binding]; other site
1008297011040	active site
1008297011041	Zn2+ binding site [ion binding]; other site
1008297011042	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1008297011043	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1008297011044	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297011045	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1008297011046	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1008297011047	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1008297011048	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1008297011049	NAD(P) binding site [chemical binding]; other site
1008297011050	catalytic residues [active]
1008297011051	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1008297011052	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1008297011053	nucleotide binding site [chemical binding]; other site
1008297011054	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1008297011055	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1008297011056	G1 box; other site
1008297011057	putative GEF interaction site [polypeptide binding]; other site
1008297011058	GTP/Mg2+ binding site [chemical binding]; other site
1008297011059	Switch I region; other site
1008297011060	G2 box; other site
1008297011061	G3 box; other site
1008297011062	Switch II region; other site
1008297011063	G4 box; other site
1008297011064	G5 box; other site
1008297011065	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1008297011066	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1008297011067	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1008297011068	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1008297011069	selenocysteine synthase; Provisional; Region: PRK04311
1008297011070	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1008297011071	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1008297011072	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1008297011073	catalytic residue [active]
1008297011074	putative glutathione S-transferase; Provisional; Region: PRK10357
1008297011075	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1008297011076	putative C-terminal domain interface [polypeptide binding]; other site
1008297011077	putative GSH binding site (G-site) [chemical binding]; other site
1008297011078	putative dimer interface [polypeptide binding]; other site
1008297011079	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1008297011080	dimer interface [polypeptide binding]; other site
1008297011081	N-terminal domain interface [polypeptide binding]; other site
1008297011082	putative substrate binding pocket (H-site) [chemical binding]; other site
1008297011083	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1008297011084	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1008297011085	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1008297011086	active site
1008297011087	P-loop; other site
1008297011088	phosphorylation site [posttranslational modification]
1008297011089	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297011090	active site
1008297011091	phosphorylation site [posttranslational modification]
1008297011092	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1008297011093	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1008297011094	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1008297011095	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1008297011096	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1008297011097	hypothetical protein; Provisional; Region: PRK11020
1008297011098	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
1008297011099	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1008297011100	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1008297011101	trimer interface [polypeptide binding]; other site
1008297011102	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
1008297011103	Haemagglutinin; Region: HIM; pfam05662
1008297011104	Haemagglutinin; Region: HIM; pfam05662
1008297011105	YadA-like C-terminal region; Region: YadA; pfam03895
1008297011106	L-lactate permease; Provisional; Region: PRK10420
1008297011107	glycolate transporter; Provisional; Region: PRK09695
1008297011108	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1008297011109	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297011110	DNA-binding site [nucleotide binding]; DNA binding site
1008297011111	FCD domain; Region: FCD; pfam07729
1008297011112	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1008297011113	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1008297011114	active site
1008297011115	substrate binding site [chemical binding]; other site
1008297011116	FMN binding site [chemical binding]; other site
1008297011117	putative catalytic residues [active]
1008297011118	putative rRNA methylase; Provisional; Region: PRK10358
1008297011119	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1008297011120	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297011121	DNA binding site [nucleotide binding]
1008297011122	domain linker motif; other site
1008297011123	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1008297011124	putative dimerization interface [polypeptide binding]; other site
1008297011125	putative ligand binding site [chemical binding]; other site
1008297011126	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1008297011127	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1008297011128	active site pocket [active]
1008297011129	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297011130	D-galactonate transporter; Region: 2A0114; TIGR00893
1008297011131	putative substrate translocation pore; other site
1008297011132	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1008297011133	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1008297011134	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1008297011135	trimer interface [polypeptide binding]; other site
1008297011136	active site
1008297011137	substrate binding site [chemical binding]; other site
1008297011138	CoA binding site [chemical binding]; other site
1008297011139	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1008297011140	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1008297011141	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1008297011142	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1008297011143	SecA binding site; other site
1008297011144	Preprotein binding site; other site
1008297011145	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1008297011146	GSH binding site [chemical binding]; other site
1008297011147	catalytic residues [active]
1008297011148	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1008297011149	active site residue [active]
1008297011150	phosphoglyceromutase; Provisional; Region: PRK05434
1008297011151	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1008297011152	AmiB activator; Provisional; Region: PRK11637
1008297011153	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1008297011154	Peptidase family M23; Region: Peptidase_M23; pfam01551
1008297011155	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1008297011156	NodB motif; other site
1008297011157	putative active site [active]
1008297011158	putative catalytic site [active]
1008297011159	Zn binding site [ion binding]; other site
1008297011160	putative glycosyl transferase; Provisional; Region: PRK10073
1008297011161	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1008297011162	active site
1008297011163	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1008297011164	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1008297011165	NAD(P) binding site [chemical binding]; other site
1008297011166	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1008297011167	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1008297011168	substrate-cofactor binding pocket; other site
1008297011169	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297011170	catalytic residue [active]
1008297011171	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1008297011172	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1008297011173	NADP binding site [chemical binding]; other site
1008297011174	homopentamer interface [polypeptide binding]; other site
1008297011175	substrate binding site [chemical binding]; other site
1008297011176	active site
1008297011177	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1008297011178	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1008297011179	putative active site [active]
1008297011180	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1008297011181	Glycosyltransferase family 9 (heptosyltransferase); Region: Glyco_transf_9; pfam01075
1008297011182	putative active site [active]
1008297011183	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1008297011184	O-antigen ligase RfaL; Provisional; Region: PRK15487
1008297011185	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
1008297011186	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1008297011187	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
1008297011188	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
1008297011189	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1008297011190	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1008297011191	Ligand binding site; other site
1008297011192	metal-binding site
1008297011193	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1008297011194	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1008297011195	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1008297011196	Ligand binding site; other site
1008297011197	metal-binding site
1008297011198	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1008297011199	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
1008297011200	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1008297011201	putative ADP-binding pocket [chemical binding]; other site
1008297011202	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1008297011203	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
1008297011204	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1008297011205	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1008297011206	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1008297011207	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1008297011208	putative active site [active]
1008297011209	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1008297011210	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1008297011211	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1008297011212	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1008297011213	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1008297011214	active site
1008297011215	(T/H)XGH motif; other site
1008297011216	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1008297011217	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1008297011218	DNA binding site [nucleotide binding]
1008297011219	catalytic residue [active]
1008297011220	H2TH interface [polypeptide binding]; other site
1008297011221	putative catalytic residues [active]
1008297011222	turnover-facilitating residue; other site
1008297011223	intercalation triad [nucleotide binding]; other site
1008297011224	8OG recognition residue [nucleotide binding]; other site
1008297011225	putative reading head residues; other site
1008297011226	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1008297011227	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1008297011228	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1008297011229	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1008297011230	hypothetical protein; Reviewed; Region: PRK00024
1008297011231	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1008297011232	MPN+ (JAMM) motif; other site
1008297011233	Zinc-binding site [ion binding]; other site
1008297011234	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1008297011235	Flavoprotein; Region: Flavoprotein; pfam02441
1008297011236	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1008297011237	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1008297011238	trimer interface [polypeptide binding]; other site
1008297011239	active site
1008297011240	division inhibitor protein; Provisional; Region: slmA; PRK09480
1008297011241	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297011242	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1008297011243	active site
1008297011244	ribonuclease PH; Reviewed; Region: rph; PRK00173
1008297011245	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1008297011246	hexamer interface [polypeptide binding]; other site
1008297011247	active site
1008297011248	hypothetical protein; Provisional; Region: PRK11820
1008297011249	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1008297011250	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1008297011251	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297011252	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297011253	dimerization interface [polypeptide binding]; other site
1008297011254	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1008297011255	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1008297011256	Predicted membrane protein [Function unknown]; Region: COG2860
1008297011257	UPF0126 domain; Region: UPF0126; pfam03458
1008297011258	UPF0126 domain; Region: UPF0126; pfam03458
1008297011259	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1008297011260	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1008297011261	nucleotide binding pocket [chemical binding]; other site
1008297011262	K-X-D-G motif; other site
1008297011263	catalytic site [active]
1008297011264	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1008297011265	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1008297011266	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1008297011267	catalytic site [active]
1008297011268	G-X2-G-X-G-K; other site
1008297011269	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1008297011270	potential frameshift: common BLAST hit: gi|379703004|ref|YP_005244732.1| (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate
1008297011271	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1008297011272	Zn2+ binding site [ion binding]; other site
1008297011273	Mg2+ binding site [ion binding]; other site
1008297011274	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1008297011275	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1008297011276	synthetase active site [active]
1008297011277	metal binding site [ion binding]; metal-binding site
1008297011278	NTP binding site [chemical binding]; other site
1008297011279	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1008297011280	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1008297011281	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1008297011282	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1008297011283	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1008297011284	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1008297011285	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1008297011286	generic binding surface II; other site
1008297011287	ssDNA binding site; other site
1008297011288	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1008297011289	ATP binding site [chemical binding]; other site
1008297011290	putative Mg++ binding site [ion binding]; other site
1008297011291	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297011292	nucleotide binding region [chemical binding]; other site
1008297011293	ATP-binding site [chemical binding]; other site
1008297011294	hypothetical protein (pseudogene)
1008297011295	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1008297011296	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1008297011297	AsmA family; Region: AsmA; pfam05170
1008297011298	putative alpha-glucosidase; Provisional; Region: PRK10658
1008297011299	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1008297011300	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1008297011301	active site
1008297011302	homotrimer interface [polypeptide binding]; other site
1008297011303	catalytic site [active]
1008297011304	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1008297011305	putative transporter; Provisional; Region: PRK11462
1008297011306	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1008297011307	putative ATP binding protein (pseudogene)
1008297011308	Virulence protein [General function prediction only]; Region: COG3943
1008297011309	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1008297011310	autotransport protein MisL; Provisional; Region: PRK15313
1008297011311	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1008297011312	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1008297011313	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1008297011314	DNA binding site [nucleotide binding]
1008297011315	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1008297011316	Isochorismatase family; Region: Isochorismatase; pfam00857
1008297011317	catalytic triad [active]
1008297011318	dimer interface [polypeptide binding]; other site
1008297011319	conserved cis-peptide bond; other site
1008297011320	magnesium-transporting ATPase; Provisional; Region: PRK15122
1008297011321	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1008297011322	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1008297011323	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1008297011324	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297011325	motif II; other site
1008297011326	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1008297011327	magnesium transport protein MgtC; Provisional; Region: PRK15385
1008297011328	MgtC family; Region: MgtC; pfam02308
1008297011329	EamA-like transporter family; Region: EamA; pfam00892
1008297011330	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1008297011331	EamA-like transporter family; Region: EamA; pfam00892
1008297011332	hypothetical protein; Provisional; Region: PRK09956
1008297011333	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1008297011334	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1008297011335	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1008297011336	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
1008297011337	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1008297011338	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1008297011339	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1008297011340	active site
1008297011341	phosphorylation site [posttranslational modification]
1008297011342	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1008297011343	active pocket/dimerization site; other site
1008297011344	active site
1008297011345	phosphorylation site [posttranslational modification]
1008297011346	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1008297011347	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297011348	Walker A motif; other site
1008297011349	ATP binding site [chemical binding]; other site
1008297011350	Walker B motif; other site
1008297011351	arginine finger; other site
1008297011352	Transcriptional antiterminator [Transcription]; Region: COG3933
1008297011353	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1008297011354	active site
1008297011355	active pocket/dimerization site; other site
1008297011356	phosphorylation site [posttranslational modification]
1008297011357	PRD domain; Region: PRD; pfam00874
1008297011358	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1008297011359	beta-galactosidase; Region: BGL; TIGR03356
1008297011360	putative inner membrane transport protein (pseudogene)
1008297011361	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
1008297011362	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1008297011363	dimerization domain swap beta strand [polypeptide binding]; other site
1008297011364	regulatory protein interface [polypeptide binding]; other site
1008297011365	active site
1008297011366	regulatory phosphorylation site [posttranslational modification]; other site
1008297011367	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1008297011368	intersubunit interface [polypeptide binding]; other site
1008297011369	active site
1008297011370	zinc binding site [ion binding]; other site
1008297011371	Na+ binding site [ion binding]; other site
1008297011372	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
1008297011373	putative N- and C-terminal domain interface [polypeptide binding]; other site
1008297011374	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1008297011375	putative active site [active]
1008297011376	putative carbohydrate binding site [chemical binding]; other site
1008297011377	putative MgATP binding site [chemical binding]; other site
1008297011378	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1008297011379	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1008297011380	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1008297011381	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297011382	active site
1008297011383	phosphorylation site [posttranslational modification]
1008297011384	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1008297011385	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297011386	DNA-binding site [nucleotide binding]; DNA binding site
1008297011387	UTRA domain; Region: UTRA; pfam07702
1008297011388	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1008297011389	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1008297011390	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297011391	putative substrate translocation pore; other site
1008297011392	regulatory protein UhpC; Provisional; Region: PRK11663
1008297011393	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297011394	putative substrate translocation pore; other site
1008297011395	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1008297011396	MASE1; Region: MASE1; pfam05231
1008297011397	Histidine kinase; Region: HisKA_3; pfam07730
1008297011398	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297011399	ATP binding site [chemical binding]; other site
1008297011400	Mg2+ binding site [ion binding]; other site
1008297011401	G-X-G motif; other site
1008297011402	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1008297011403	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297011404	active site
1008297011405	phosphorylation site [posttranslational modification]
1008297011406	intermolecular recognition site; other site
1008297011407	dimerization interface [polypeptide binding]; other site
1008297011408	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297011409	DNA binding residues [nucleotide binding]
1008297011410	dimerization interface [polypeptide binding]; other site
1008297011411	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
1008297011412	active site
1008297011413	catalytic residues [active]
1008297011414	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1008297011415	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297011416	putative substrate translocation pore; other site
1008297011417	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297011418	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1008297011419	substrate binding site [chemical binding]; other site
1008297011420	dimer interface [polypeptide binding]; other site
1008297011421	ATP binding site [chemical binding]; other site
1008297011422	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1008297011423	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1008297011424	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297011425	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1008297011426	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1008297011427	putative valine binding site [chemical binding]; other site
1008297011428	dimer interface [polypeptide binding]; other site
1008297011429	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1008297011430	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1008297011431	PYR/PP interface [polypeptide binding]; other site
1008297011432	dimer interface [polypeptide binding]; other site
1008297011433	TPP binding site [chemical binding]; other site
1008297011434	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1008297011435	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1008297011436	TPP-binding site [chemical binding]; other site
1008297011437	dimer interface [polypeptide binding]; other site
1008297011438	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1008297011439	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1008297011440	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297011441	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1008297011442	putative substrate translocation pore; other site
1008297011443	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
1008297011444	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297011445	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1008297011446	dimerization interface [polypeptide binding]; other site
1008297011447	substrate binding pocket [chemical binding]; other site
1008297011448	permease DsdX; Provisional; Region: PRK09921
1008297011449	gluconate transporter; Region: gntP; TIGR00791
1008297011450	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1008297011451	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1008297011452	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1008297011453	catalytic residue [active]
1008297011454	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
1008297011455	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
1008297011456	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1008297011457	Predicted membrane protein [Function unknown]; Region: COG2149
1008297011458	putative transporter; Validated; Region: PRK03818
1008297011459	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1008297011460	TrkA-C domain; Region: TrkA_C; pfam02080
1008297011461	TrkA-C domain; Region: TrkA_C; pfam02080
1008297011462	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1008297011463	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1008297011464	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1008297011465	putative dimer interface [polypeptide binding]; other site
1008297011466	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1008297011467	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1008297011468	putative dimer interface [polypeptide binding]; other site
1008297011469	hypothetical protein; Provisional; Region: PRK11616
1008297011470	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1008297011471	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1008297011472	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1008297011473	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1008297011474	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1008297011475	catalytic residues [active]
1008297011476	central insert; other site
1008297011477	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1008297011478	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1008297011479	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1008297011480	heme exporter protein CcmC; Region: ccmC; TIGR01191
1008297011481	heme exporter protein CcmB; Region: ccmB; TIGR01190
1008297011482	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297011483	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1008297011484	Walker A/P-loop; other site
1008297011485	ATP binding site [chemical binding]; other site
1008297011486	Q-loop/lid; other site
1008297011487	ABC transporter signature motif; other site
1008297011488	Walker B; other site
1008297011489	D-loop; other site
1008297011490	H-loop/switch region; other site
1008297011491	Haem-binding domain; Region: Haem_bd; pfam14376
1008297011492	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1008297011493	chaperone protein TorD; Validated; Region: torD; PRK04976
1008297011494	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
1008297011495	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1008297011496	molybdopterin cofactor binding site [chemical binding]; other site
1008297011497	substrate binding site [chemical binding]; other site
1008297011498	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1008297011499	molybdopterin cofactor binding site; other site
1008297011500	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
1008297011501	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1008297011502	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
1008297011503	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297011504	active site
1008297011505	phosphorylation site [posttranslational modification]
1008297011506	intermolecular recognition site; other site
1008297011507	dimerization interface [polypeptide binding]; other site
1008297011508	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297011509	DNA binding site [nucleotide binding]
1008297011510	potential frameshift: common BLAST hit: gi|379703086|ref|YP_005244814.1| periplasmic sensory protein associated with the TorRS two-component
1008297011511	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1008297011512	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1008297011513	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
1008297011514	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297011515	dimer interface [polypeptide binding]; other site
1008297011516	phosphorylation site [posttranslational modification]
1008297011517	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297011518	ATP binding site [chemical binding]; other site
1008297011519	Mg2+ binding site [ion binding]; other site
1008297011520	G-X-G motif; other site
1008297011521	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297011522	active site
1008297011523	phosphorylation site [posttranslational modification]
1008297011524	intermolecular recognition site; other site
1008297011525	dimerization interface [polypeptide binding]; other site
1008297011526	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1008297011527	putative binding surface; other site
1008297011528	active site
1008297011529	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297011530	D-galactonate transporter; Region: 2A0114; TIGR00893
1008297011531	putative substrate translocation pore; other site
1008297011532	galactonate dehydratase; Provisional; Region: PRK14017
1008297011533	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
1008297011534	putative active site pocket [active]
1008297011535	putative metal binding site [ion binding]; other site
1008297011536	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
1008297011537	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1008297011538	active site
1008297011539	intersubunit interface [polypeptide binding]; other site
1008297011540	catalytic residue [active]
1008297011541	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1008297011542	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
1008297011543	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1008297011544	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297011545	DNA-binding site [nucleotide binding]; DNA binding site
1008297011546	FCD domain; Region: FCD; pfam07729
1008297011547	sugar phosphate phosphatase; Provisional; Region: PRK10513
1008297011548	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297011549	active site
1008297011550	motif I; other site
1008297011551	motif II; other site
1008297011552	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297011553	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297011554	D-galactonate transporter; Region: 2A0114; TIGR00893
1008297011555	putative substrate translocation pore; other site
1008297011556	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297011557	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1008297011558	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1008297011559	active site pocket [active]
1008297011560	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297011561	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297011562	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1008297011563	putative dimerization interface [polypeptide binding]; other site
1008297011564	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1008297011565	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297011566	Mg2+ binding site [ion binding]; other site
1008297011567	G-X-G motif; other site
1008297011568	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1008297011569	anchoring element; other site
1008297011570	dimer interface [polypeptide binding]; other site
1008297011571	ATP binding site [chemical binding]; other site
1008297011572	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1008297011573	active site
1008297011574	putative metal-binding site [ion binding]; other site
1008297011575	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1008297011576	recF protein; Region: recf; TIGR00611
1008297011577	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297011578	Walker A/P-loop; other site
1008297011579	ATP binding site [chemical binding]; other site
1008297011580	Q-loop/lid; other site
1008297011581	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297011582	ABC transporter signature motif; other site
1008297011583	Walker B; other site
1008297011584	D-loop; other site
1008297011585	H-loop/switch region; other site
1008297011586	DNA polymerase III subunit beta; Validated; Region: PRK05643
1008297011587	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1008297011588	putative DNA binding surface [nucleotide binding]; other site
1008297011589	dimer interface [polypeptide binding]; other site
1008297011590	beta-clamp/clamp loader binding surface; other site
1008297011591	beta-clamp/translesion DNA polymerase binding surface; other site
1008297011592	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1008297011593	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1008297011594	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297011595	Walker A motif; other site
1008297011596	ATP binding site [chemical binding]; other site
1008297011597	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1008297011598	Walker B motif; other site
1008297011599	arginine finger; other site
1008297011600	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1008297011601	DnaA box-binding interface [nucleotide binding]; other site
1008297011602	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1008297011603	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1008297011604	membrane protein insertase; Provisional; Region: PRK01318
1008297011605	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
1008297011606	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1008297011607	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1008297011608	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1008297011609	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1008297011610	G1 box; other site
1008297011611	GTP/Mg2+ binding site [chemical binding]; other site
1008297011612	Switch I region; other site
1008297011613	G2 box; other site
1008297011614	Switch II region; other site
1008297011615	G3 box; other site
1008297011616	G4 box; other site
1008297011617	G5 box; other site
1008297011618	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1008297011619	putative bacteriophage integrase (pseudogene)
1008297011620	putative transferase, LIC12162 family; Region: o_ant_LIC12162; TIGR04331
1008297011621	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1008297011622	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
1008297011623	putative active site [active]
1008297011624	putative NTP binding site [chemical binding]; other site
1008297011625	putative nucleic acid binding site [nucleotide binding]; other site
1008297011626	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1008297011627	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297011628	putative substrate translocation pore; other site
1008297011629	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1008297011630	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297011631	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1008297011632	substrate binding pocket [chemical binding]; other site
1008297011633	dimerization interface [polypeptide binding]; other site
1008297011634	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1008297011635	Predicted flavoprotein [General function prediction only]; Region: COG0431
1008297011636	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1008297011637	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1008297011638	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1008297011639	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297011640	active site
1008297011641	motif I; other site
1008297011642	motif II; other site
1008297011643	transcriptional regulator PhoU; Provisional; Region: PRK11115
1008297011644	PhoU domain; Region: PhoU; pfam01895
1008297011645	PhoU domain; Region: PhoU; pfam01895
1008297011646	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1008297011647	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1008297011648	Walker A/P-loop; other site
1008297011649	ATP binding site [chemical binding]; other site
1008297011650	Q-loop/lid; other site
1008297011651	ABC transporter signature motif; other site
1008297011652	Walker B; other site
1008297011653	D-loop; other site
1008297011654	H-loop/switch region; other site
1008297011655	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1008297011656	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297011657	dimer interface [polypeptide binding]; other site
1008297011658	conserved gate region; other site
1008297011659	putative PBP binding loops; other site
1008297011660	ABC-ATPase subunit interface; other site
1008297011661	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1008297011662	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297011663	dimer interface [polypeptide binding]; other site
1008297011664	conserved gate region; other site
1008297011665	putative PBP binding loops; other site
1008297011666	ABC-ATPase subunit interface; other site
1008297011667	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297011668	substrate binding pocket [chemical binding]; other site
1008297011669	membrane-bound complex binding site; other site
1008297011670	hinge residues; other site
1008297011671	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1008297011672	active site
1008297011673	P-loop; other site
1008297011674	phosphorylation site [posttranslational modification]
1008297011675	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1008297011676	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1008297011677	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
1008297011678	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1008297011679	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1008297011680	shikimate binding site; other site
1008297011681	NAD(P) binding site [chemical binding]; other site
1008297011682	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1008297011683	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1008297011684	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1008297011685	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1008297011686	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1008297011687	glutaminase active site [active]
1008297011688	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1008297011689	dimer interface [polypeptide binding]; other site
1008297011690	active site
1008297011691	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1008297011692	dimer interface [polypeptide binding]; other site
1008297011693	active site
1008297011694	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1008297011695	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1008297011696	Substrate binding site; other site
1008297011697	Mg++ binding site; other site
1008297011698	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1008297011699	active site
1008297011700	substrate binding site [chemical binding]; other site
1008297011701	CoA binding site [chemical binding]; other site
1008297011702	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1008297011703	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
1008297011704	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1008297011705	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1008297011706	gamma subunit interface [polypeptide binding]; other site
1008297011707	epsilon subunit interface [polypeptide binding]; other site
1008297011708	LBP interface [polypeptide binding]; other site
1008297011709	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1008297011710	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1008297011711	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1008297011712	alpha subunit interaction interface [polypeptide binding]; other site
1008297011713	Walker A motif; other site
1008297011714	ATP binding site [chemical binding]; other site
1008297011715	Walker B motif; other site
1008297011716	inhibitor binding site; inhibition site
1008297011717	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1008297011718	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1008297011719	core domain interface [polypeptide binding]; other site
1008297011720	delta subunit interface [polypeptide binding]; other site
1008297011721	epsilon subunit interface [polypeptide binding]; other site
1008297011722	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1008297011723	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1008297011724	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1008297011725	beta subunit interaction interface [polypeptide binding]; other site
1008297011726	Walker A motif; other site
1008297011727	ATP binding site [chemical binding]; other site
1008297011728	Walker B motif; other site
1008297011729	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1008297011730	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1008297011731	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1008297011732	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1008297011733	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1008297011734	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1008297011735	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1008297011736	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1008297011737	ATP synthase I chain; Region: ATP_synt_I; cl09170
1008297011738	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1008297011739	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297011740	S-adenosylmethionine binding site [chemical binding]; other site
1008297011741	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1008297011742	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1008297011743	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1008297011744	FMN-binding protein MioC; Provisional; Region: PRK09004
1008297011745	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1008297011746	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1008297011747	putative DNA binding site [nucleotide binding]; other site
1008297011748	putative Zn2+ binding site [ion binding]; other site
1008297011749	AsnC family; Region: AsnC_trans_reg; pfam01037
1008297011750	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1008297011751	dimer interface [polypeptide binding]; other site
1008297011752	active site
1008297011753	hypothetical protein; Provisional; Region: yieM; PRK10997
1008297011754	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1008297011755	metal ion-dependent adhesion site (MIDAS); other site
1008297011756	regulatory ATPase RavA; Provisional; Region: PRK13531
1008297011757	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297011758	Walker A motif; other site
1008297011759	ATP binding site [chemical binding]; other site
1008297011760	Walker B motif; other site
1008297011761	arginine finger; other site
1008297011762	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1008297011763	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1008297011764	potassium uptake protein; Region: kup; TIGR00794
1008297011765	D-ribose pyranase; Provisional; Region: PRK11797
1008297011766	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1008297011767	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1008297011768	Walker A/P-loop; other site
1008297011769	ATP binding site [chemical binding]; other site
1008297011770	Q-loop/lid; other site
1008297011771	ABC transporter signature motif; other site
1008297011772	Walker B; other site
1008297011773	D-loop; other site
1008297011774	H-loop/switch region; other site
1008297011775	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1008297011776	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1008297011777	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1008297011778	TM-ABC transporter signature motif; other site
1008297011779	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1008297011780	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1008297011781	ligand binding site [chemical binding]; other site
1008297011782	dimerization interface [polypeptide binding]; other site
1008297011783	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297011784	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1008297011785	substrate binding site [chemical binding]; other site
1008297011786	dimer interface [polypeptide binding]; other site
1008297011787	ATP binding site [chemical binding]; other site
1008297011788	transcriptional repressor RbsR; Provisional; Region: PRK10423
1008297011789	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297011790	DNA binding site [nucleotide binding]
1008297011791	domain linker motif; other site
1008297011792	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1008297011793	dimerization interface [polypeptide binding]; other site
1008297011794	ligand binding site [chemical binding]; other site
1008297011795	putative transmembrane efflux protein (pseudogene)
1008297011796	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1008297011797	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297011798	DNA-binding site [nucleotide binding]; DNA binding site
1008297011799	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1008297011800	transcriptional regulator HdfR; Provisional; Region: PRK03601
1008297011801	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297011802	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1008297011803	dimerization interface [polypeptide binding]; other site
1008297011804	hypothetical protein; Provisional; Region: PRK11027
1008297011805	putative ATP-dependent protease; Provisional; Region: PRK09862
1008297011806	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1008297011807	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297011808	Walker A motif; other site
1008297011809	ATP binding site [chemical binding]; other site
1008297011810	Walker B motif; other site
1008297011811	arginine finger; other site
1008297011812	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1008297011813	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1008297011814	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1008297011815	PYR/PP interface [polypeptide binding]; other site
1008297011816	dimer interface [polypeptide binding]; other site
1008297011817	TPP binding site [chemical binding]; other site
1008297011818	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1008297011819	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1008297011820	TPP-binding site [chemical binding]; other site
1008297011821	dimer interface [polypeptide binding]; other site
1008297011822	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1008297011823	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1008297011824	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1008297011825	homodimer interface [polypeptide binding]; other site
1008297011826	substrate-cofactor binding pocket; other site
1008297011827	catalytic residue [active]
1008297011828	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1008297011829	threonine dehydratase; Reviewed; Region: PRK09224
1008297011830	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1008297011831	tetramer interface [polypeptide binding]; other site
1008297011832	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297011833	catalytic residue [active]
1008297011834	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1008297011835	putative Ile/Val binding site [chemical binding]; other site
1008297011836	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1008297011837	putative Ile/Val binding site [chemical binding]; other site
1008297011838	Phage-related protein [Function unknown]; Region: COG4679
1008297011839	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
1008297011840	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297011841	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1008297011842	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1008297011843	putative dimerization interface [polypeptide binding]; other site
1008297011844	ketol-acid reductoisomerase; Validated; Region: PRK05225
1008297011845	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1008297011846	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1008297011847	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1008297011848	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1008297011849	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1008297011850	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
1008297011851	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1008297011852	Part of AAA domain; Region: AAA_19; pfam13245
1008297011853	Family description; Region: UvrD_C_2; pfam13538
1008297011854	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1008297011855	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1008297011856	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1008297011857	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1008297011858	ATP binding site [chemical binding]; other site
1008297011859	Mg++ binding site [ion binding]; other site
1008297011860	motif III; other site
1008297011861	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297011862	nucleotide binding region [chemical binding]; other site
1008297011863	ATP-binding site [chemical binding]; other site
1008297011864	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1008297011865	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1008297011866	catalytic residues [active]
1008297011867	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1008297011868	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1008297011869	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1008297011870	RNA binding site [nucleotide binding]; other site
1008297011871	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1008297011872	multimer interface [polypeptide binding]; other site
1008297011873	Walker A motif; other site
1008297011874	ATP binding site [chemical binding]; other site
1008297011875	Walker B motif; other site
1008297011876	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1008297011877	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1008297011878	Mg++ binding site [ion binding]; other site
1008297011879	putative catalytic motif [active]
1008297011880	substrate binding site [chemical binding]; other site
1008297011881	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1008297011882	Chain length determinant protein; Region: Wzz; pfam02706
1008297011883	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
1008297011884	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1008297011885	homodimer interface [polypeptide binding]; other site
1008297011886	active site
1008297011887	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1008297011888	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1008297011889	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1008297011890	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
1008297011891	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1008297011892	NAD binding site [chemical binding]; other site
1008297011893	substrate binding site [chemical binding]; other site
1008297011894	homodimer interface [polypeptide binding]; other site
1008297011895	active site
1008297011896	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1008297011897	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1008297011898	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
1008297011899	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1008297011900	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1008297011901	inhibitor-cofactor binding pocket; inhibition site
1008297011902	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297011903	catalytic residue [active]
1008297011904	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1008297011905	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1008297011906	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1008297011907	putative common antigen polymerase; Provisional; Region: PRK02975
1008297011908	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1008297011909	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1008297011910	putative transport protein YifK; Provisional; Region: PRK10746
1008297011911	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1008297011912	HemY protein N-terminus; Region: HemY_N; pfam07219
1008297011913	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1008297011914	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1008297011915	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1008297011916	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1008297011917	active site
1008297011918	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1008297011919	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1008297011920	active site
1008297011921	domain interfaces; other site
1008297011922	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1008297011923	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1008297011924	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1008297011925	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1008297011926	putative iron binding site [ion binding]; other site
1008297011927	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
1008297011928	putative exported protein (pseudogene)
1008297011929	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1008297011930	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1008297011931	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1008297011932	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1008297011933	hypothetical protein; Provisional; Region: PRK10963
1008297011934	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1008297011935	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1008297011936	active site
1008297011937	Int/Topo IB signature motif; other site
1008297011938	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1008297011939	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297011940	motif II; other site
1008297011941	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1008297011942	Part of AAA domain; Region: AAA_19; pfam13245
1008297011943	Family description; Region: UvrD_C_2; pfam13538
1008297011944	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1008297011945	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1008297011946	Cl binding site [ion binding]; other site
1008297011947	oligomer interface [polypeptide binding]; other site
1008297011948	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
1008297011949	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1008297011950	EamA-like transporter family; Region: EamA; cl17759
1008297011951	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1008297011952	CoenzymeA binding site [chemical binding]; other site
1008297011953	subunit interaction site [polypeptide binding]; other site
1008297011954	PHB binding site; other site
1008297011955	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1008297011956	dimerization interface [polypeptide binding]; other site
1008297011957	substrate binding site [chemical binding]; other site
1008297011958	active site
1008297011959	calcium binding site [ion binding]; other site
1008297011960	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1008297011961	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1008297011962	ATP binding site [chemical binding]; other site
1008297011963	putative Mg++ binding site [ion binding]; other site
1008297011964	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1008297011965	nucleotide binding region [chemical binding]; other site
1008297011966	ATP-binding site [chemical binding]; other site
1008297011967	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1008297011968	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1008297011969	threonine efflux system; Provisional; Region: PRK10229
1008297011970	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1008297011971	lysophospholipase L2; Provisional; Region: PRK10749
1008297011972	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1008297011973	putative hydrolase; Provisional; Region: PRK10976
1008297011974	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297011975	active site
1008297011976	motif I; other site
1008297011977	motif II; other site
1008297011978	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297011979	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1008297011980	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297011981	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1008297011982	putative dimerization interface [polypeptide binding]; other site
1008297011983	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1008297011984	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1008297011985	THF binding site; other site
1008297011986	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1008297011987	substrate binding site [chemical binding]; other site
1008297011988	THF binding site; other site
1008297011989	zinc-binding site [ion binding]; other site
1008297011990	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1008297011991	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297011992	FeS/SAM binding site; other site
1008297011993	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1008297011994	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1008297011995	uridine phosphorylase; Provisional; Region: PRK11178
1008297011996	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
1008297011997	DNA recombination protein RmuC; Provisional; Region: PRK10361
1008297011998	RmuC family; Region: RmuC; pfam02646
1008297011999	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1008297012000	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297012001	S-adenosylmethionine binding site [chemical binding]; other site
1008297012002	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
1008297012003	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1008297012004	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1008297012005	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1008297012006	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1008297012007	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1008297012008	sec-independent translocase; Provisional; Region: PRK01770
1008297012009	sec-independent translocase; Provisional; Region: tatB; PRK00404
1008297012010	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1008297012011	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1008297012012	active site
1008297012013	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1008297012014	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1008297012015	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
1008297012016	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1008297012017	FMN reductase; Validated; Region: fre; PRK08051
1008297012018	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1008297012019	FAD binding pocket [chemical binding]; other site
1008297012020	FAD binding motif [chemical binding]; other site
1008297012021	phosphate binding motif [ion binding]; other site
1008297012022	beta-alpha-beta structure motif; other site
1008297012023	NAD binding pocket [chemical binding]; other site
1008297012024	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1008297012025	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1008297012026	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1008297012027	dimer interface [polypeptide binding]; other site
1008297012028	active site
1008297012029	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1008297012030	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1008297012031	substrate binding site [chemical binding]; other site
1008297012032	oxyanion hole (OAH) forming residues; other site
1008297012033	trimer interface [polypeptide binding]; other site
1008297012034	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1008297012035	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1008297012036	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1008297012037	proline dipeptidase; Provisional; Region: PRK13607
1008297012038	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1008297012039	active site
1008297012040	hypothetical protein; Provisional; Region: PRK11568
1008297012041	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1008297012042	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1008297012043	potassium transporter; Provisional; Region: PRK10750
1008297012044	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1008297012045	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1008297012046	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1008297012047	Walker A motif; other site
1008297012048	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1008297012049	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1008297012050	GTP binding site; other site
1008297012051	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1008297012052	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1008297012053	serine/threonine protein kinase; Provisional; Region: PRK11768
1008297012054	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1008297012055	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1008297012056	catalytic residues [active]
1008297012057	hinge region; other site
1008297012058	alpha helical domain; other site
1008297012059	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1008297012060	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1008297012061	putative acyl-acceptor binding pocket; other site
1008297012062	DNA polymerase I; Provisional; Region: PRK05755
1008297012063	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1008297012064	active site
1008297012065	metal binding site 1 [ion binding]; metal-binding site
1008297012066	putative 5' ssDNA interaction site; other site
1008297012067	metal binding site 3; metal-binding site
1008297012068	metal binding site 2 [ion binding]; metal-binding site
1008297012069	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1008297012070	putative DNA binding site [nucleotide binding]; other site
1008297012071	putative metal binding site [ion binding]; other site
1008297012072	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1008297012073	active site
1008297012074	catalytic site [active]
1008297012075	substrate binding site [chemical binding]; other site
1008297012076	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1008297012077	active site
1008297012078	DNA binding site [nucleotide binding]
1008297012079	catalytic site [active]
1008297012080	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1008297012081	G1 box; other site
1008297012082	GTP/Mg2+ binding site [chemical binding]; other site
1008297012083	Switch I region; other site
1008297012084	G2 box; other site
1008297012085	G3 box; other site
1008297012086	Switch II region; other site
1008297012087	G4 box; other site
1008297012088	G5 box; other site
1008297012089	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
1008297012090	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1008297012091	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297012092	FeS/SAM binding site; other site
1008297012093	HemN C-terminal domain; Region: HemN_C; pfam06969
1008297012094	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1008297012095	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297012096	active site
1008297012097	phosphorylation site [posttranslational modification]
1008297012098	intermolecular recognition site; other site
1008297012099	dimerization interface [polypeptide binding]; other site
1008297012100	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297012101	Walker A motif; other site
1008297012102	ATP binding site [chemical binding]; other site
1008297012103	Walker B motif; other site
1008297012104	arginine finger; other site
1008297012105	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1008297012106	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1008297012107	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1008297012108	putative active site [active]
1008297012109	heme pocket [chemical binding]; other site
1008297012110	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297012111	dimer interface [polypeptide binding]; other site
1008297012112	phosphorylation site [posttranslational modification]
1008297012113	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297012114	ATP binding site [chemical binding]; other site
1008297012115	Mg2+ binding site [ion binding]; other site
1008297012116	G-X-G motif; other site
1008297012117	glutamine synthetase; Provisional; Region: glnA; PRK09469
1008297012118	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1008297012119	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1008297012120	GTP-binding protein; Provisional; Region: PRK10218
1008297012121	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1008297012122	G1 box; other site
1008297012123	putative GEF interaction site [polypeptide binding]; other site
1008297012124	GTP/Mg2+ binding site [chemical binding]; other site
1008297012125	Switch I region; other site
1008297012126	G2 box; other site
1008297012127	G3 box; other site
1008297012128	Switch II region; other site
1008297012129	G4 box; other site
1008297012130	G5 box; other site
1008297012131	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1008297012132	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1008297012133	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297012134	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1008297012135	active site
1008297012136	motif I; other site
1008297012137	motif II; other site
1008297012138	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297012139	coproporphyrinogen III oxidase; Validated; Region: PRK08208
1008297012140	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297012141	FeS/SAM binding site; other site
1008297012142	HemN C-terminal domain; Region: HemN_C; pfam06969
1008297012143	Sulfatase; Region: Sulfatase; cl17466
1008297012144	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1008297012145	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1008297012146	Leucine-rich repeats; other site
1008297012147	Substrate binding site [chemical binding]; other site
1008297012148	outer membrane porin L; Provisional; Region: ompL; PRK09980
1008297012149	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1008297012150	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297012151	putative substrate translocation pore; other site
1008297012152	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1008297012153	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1008297012154	alpha-glucosidase; Provisional; Region: PRK10426
1008297012155	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1008297012156	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
1008297012157	putative active site [active]
1008297012158	putative catalytic site [active]
1008297012159	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
1008297012160	active site
1008297012161	catalytic residues [active]
1008297012162	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
1008297012163	dimerization interface [polypeptide binding]; other site
1008297012164	putative active cleft [active]
1008297012165	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
1008297012166	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1008297012167	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1008297012168	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297012169	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
1008297012170	substrate binding site [chemical binding]; other site
1008297012171	ATP binding site [chemical binding]; other site
1008297012172	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1008297012173	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1008297012174	putative DNA binding site [nucleotide binding]; other site
1008297012175	putative Zn2+ binding site [ion binding]; other site
1008297012176	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297012177	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1008297012178	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297012179	motif II; other site
1008297012180	hypothetical protein; Reviewed; Region: PRK01637
1008297012181	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1008297012182	putative active site [active]
1008297012183	dimerization interface [polypeptide binding]; other site
1008297012184	putative tRNAtyr binding site [nucleotide binding]; other site
1008297012185	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297012186	Coenzyme A binding pocket [chemical binding]; other site
1008297012187	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1008297012188	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
1008297012189	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
1008297012190	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1008297012191	Predicted transcriptional regulator [Transcription]; Region: COG2944
1008297012192	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1008297012193	non-specific DNA binding site [nucleotide binding]; other site
1008297012194	salt bridge; other site
1008297012195	sequence-specific DNA binding site [nucleotide binding]; other site
1008297012196	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1008297012197	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1008297012198	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1008297012199	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1008297012200	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1008297012201	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1008297012202	potential frameshift: common BLAST hit: gi|379703280|ref|YP_005245008.1| formate dehydrogenase alpha subunit
1008297012203	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297012204	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1008297012205	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1008297012206	molybdopterin cofactor binding site; other site
1008297012207	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297012208	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1008297012209	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1008297012210	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1008297012211	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1008297012212	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1008297012213	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1008297012214	non-specific DNA binding site [nucleotide binding]; other site
1008297012215	salt bridge; other site
1008297012216	sequence-specific DNA binding site [nucleotide binding]; other site
1008297012217	Cupin domain; Region: Cupin_2; cl17218
1008297012218	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1008297012219	lactaldehyde reductase; Region: lactal_redase; TIGR02638
1008297012220	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1008297012221	dimer interface [polypeptide binding]; other site
1008297012222	active site
1008297012223	metal binding site [ion binding]; metal-binding site
1008297012224	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1008297012225	intersubunit interface [polypeptide binding]; other site
1008297012226	active site
1008297012227	Zn2+ binding site [ion binding]; other site
1008297012228	L-rhamnose isomerase; Provisional; Region: PRK01076
1008297012229	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1008297012230	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1008297012231	N- and C-terminal domain interface [polypeptide binding]; other site
1008297012232	active site
1008297012233	putative catalytic site [active]
1008297012234	metal binding site [ion binding]; metal-binding site
1008297012235	ATP binding site [chemical binding]; other site
1008297012236	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1008297012237	carbohydrate binding site [chemical binding]; other site
1008297012238	transcriptional activator RhaS; Provisional; Region: PRK13503
1008297012239	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1008297012240	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297012241	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297012242	transcriptional activator RhaR; Provisional; Region: PRK13502
1008297012243	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1008297012244	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297012245	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
1008297012246	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1008297012247	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1008297012248	DctM-like transporters; Region: DctM; pfam06808
1008297012249	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
1008297012250	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1008297012251	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1008297012252	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1008297012253	superoxide dismutase; Provisional; Region: PRK10925
1008297012254	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1008297012255	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1008297012256	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1008297012257	MOSC domain; Region: MOSC; pfam03473
1008297012258	3-alpha domain; Region: 3-alpha; pfam03475
1008297012259	SnoaL-like domain; Region: SnoaL_2; pfam12680
1008297012260	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1008297012261	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297012262	dimerization interface [polypeptide binding]; other site
1008297012263	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297012264	dimer interface [polypeptide binding]; other site
1008297012265	phosphorylation site [posttranslational modification]
1008297012266	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297012267	ATP binding site [chemical binding]; other site
1008297012268	Mg2+ binding site [ion binding]; other site
1008297012269	G-X-G motif; other site
1008297012270	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1008297012271	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297012272	active site
1008297012273	intermolecular recognition site; other site
1008297012274	dimerization interface [polypeptide binding]; other site
1008297012275	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297012276	DNA binding site [nucleotide binding]
1008297012277	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1008297012278	dimer interface [polypeptide binding]; other site
1008297012279	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1008297012280	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1008297012281	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1008297012282	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1008297012283	active site
1008297012284	ADP/pyrophosphate binding site [chemical binding]; other site
1008297012285	dimerization interface [polypeptide binding]; other site
1008297012286	allosteric effector site; other site
1008297012287	fructose-1,6-bisphosphate binding site; other site
1008297012288	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1008297012289	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297012290	substrate binding pocket [chemical binding]; other site
1008297012291	membrane-bound complex binding site; other site
1008297012292	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1008297012293	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1008297012294	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1008297012295	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297012296	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1008297012297	putative substrate binding site [chemical binding]; other site
1008297012298	putative ATP binding site [chemical binding]; other site
1008297012299	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1008297012300	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1008297012301	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297012302	DNA-binding site [nucleotide binding]; DNA binding site
1008297012303	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
1008297012304	UTRA domain; Region: UTRA; pfam07702
1008297012305	CDP-diacylglycerol pyrophosphatase (pseudogene)
1008297012306	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1008297012307	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
1008297012308	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
1008297012309	putative N- and C-terminal domain interface [polypeptide binding]; other site
1008297012310	putative active site [active]
1008297012311	putative MgATP binding site [chemical binding]; other site
1008297012312	catalytic site [active]
1008297012313	metal binding site [ion binding]; metal-binding site
1008297012314	putative carbohydrate binding site [chemical binding]; other site
1008297012315	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1008297012316	transcriptional regulator LsrR; Provisional; Region: PRK15418
1008297012317	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1008297012318	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1008297012319	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1008297012320	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1008297012321	Walker A/P-loop; other site
1008297012322	ATP binding site [chemical binding]; other site
1008297012323	Q-loop/lid; other site
1008297012324	ABC transporter signature motif; other site
1008297012325	Walker B; other site
1008297012326	D-loop; other site
1008297012327	H-loop/switch region; other site
1008297012328	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1008297012329	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1008297012330	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1008297012331	TM-ABC transporter signature motif; other site
1008297012332	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1008297012333	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1008297012334	TM-ABC transporter signature motif; other site
1008297012335	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1008297012336	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1008297012337	ligand binding site [chemical binding]; other site
1008297012338	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1008297012339	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1008297012340	putative active site; other site
1008297012341	catalytic residue [active]
1008297012342	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1008297012343	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1008297012344	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1008297012345	substrate binding site [chemical binding]; other site
1008297012346	hexamer interface [polypeptide binding]; other site
1008297012347	metal binding site [ion binding]; metal-binding site
1008297012348	triosephosphate isomerase; Provisional; Region: PRK14567
1008297012349	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1008297012350	substrate binding site [chemical binding]; other site
1008297012351	dimer interface [polypeptide binding]; other site
1008297012352	catalytic triad [active]
1008297012353	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1008297012354	Predicted membrane protein [Function unknown]; Region: COG3152
1008297012355	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1008297012356	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1008297012357	FAD binding pocket [chemical binding]; other site
1008297012358	FAD binding motif [chemical binding]; other site
1008297012359	phosphate binding motif [ion binding]; other site
1008297012360	beta-alpha-beta structure motif; other site
1008297012361	NAD binding pocket [chemical binding]; other site
1008297012362	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1008297012363	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1008297012364	putative active site [active]
1008297012365	glycerol kinase; Provisional; Region: glpK; PRK00047
1008297012366	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1008297012367	N- and C-terminal domain interface [polypeptide binding]; other site
1008297012368	active site
1008297012369	MgATP binding site [chemical binding]; other site
1008297012370	catalytic site [active]
1008297012371	metal binding site [ion binding]; metal-binding site
1008297012372	glycerol binding site [chemical binding]; other site
1008297012373	homotetramer interface [polypeptide binding]; other site
1008297012374	homodimer interface [polypeptide binding]; other site
1008297012375	FBP binding site [chemical binding]; other site
1008297012376	protein IIAGlc interface [polypeptide binding]; other site
1008297012377	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1008297012378	amphipathic channel; other site
1008297012379	Asn-Pro-Ala signature motifs; other site
1008297012380	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1008297012381	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1008297012382	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
1008297012383	UbiA prenyltransferase family; Region: UbiA; pfam01040
1008297012384	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1008297012385	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297012386	Walker A motif; other site
1008297012387	ATP binding site [chemical binding]; other site
1008297012388	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1008297012389	Walker B motif; other site
1008297012390	arginine finger; other site
1008297012391	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1008297012392	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1008297012393	active site
1008297012394	HslU subunit interaction site [polypeptide binding]; other site
1008297012395	essential cell division protein FtsN; Provisional; Region: PRK10927
1008297012396	cell division protein FtsN; Provisional; Region: PRK12757
1008297012397	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297012398	DNA binding site [nucleotide binding]
1008297012399	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1008297012400	domain linker motif; other site
1008297012401	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1008297012402	dimerization interface [polypeptide binding]; other site
1008297012403	ligand binding site [chemical binding]; other site
1008297012404	primosome assembly protein PriA; Validated; Region: PRK05580
1008297012405	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1008297012406	ATP binding site [chemical binding]; other site
1008297012407	putative Mg++ binding site [ion binding]; other site
1008297012408	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1008297012409	ATP-binding site [chemical binding]; other site
1008297012410	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1008297012411	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
1008297012412	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1008297012413	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1008297012414	dimerization interface [polypeptide binding]; other site
1008297012415	DNA binding site [nucleotide binding]
1008297012416	corepressor binding sites; other site
1008297012417	cystathionine gamma-synthase; Provisional; Region: PRK08045
1008297012418	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1008297012419	homodimer interface [polypeptide binding]; other site
1008297012420	substrate-cofactor binding pocket; other site
1008297012421	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297012422	catalytic residue [active]
1008297012423	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1008297012424	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1008297012425	putative catalytic residues [active]
1008297012426	putative nucleotide binding site [chemical binding]; other site
1008297012427	putative aspartate binding site [chemical binding]; other site
1008297012428	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1008297012429	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1008297012430	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1008297012431	Conserved TM helix; Region: TM_helix; pfam05552
1008297012432	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1008297012433	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1008297012434	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1008297012435	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1008297012436	active site
1008297012437	metal binding site [ion binding]; metal-binding site
1008297012438	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1008297012439	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1008297012440	FAD binding site [chemical binding]; other site
1008297012441	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1008297012442	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1008297012443	heme binding site [chemical binding]; other site
1008297012444	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1008297012445	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
1008297012446	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1008297012447	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1008297012448	dimer interface [polypeptide binding]; other site
1008297012449	active site
1008297012450	metal binding site [ion binding]; metal-binding site
1008297012451	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1008297012452	active site
1008297012453	intersubunit interactions; other site
1008297012454	catalytic residue [active]
1008297012455	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1008297012456	dimerization domain swap beta strand [polypeptide binding]; other site
1008297012457	regulatory protein interface [polypeptide binding]; other site
1008297012458	active site
1008297012459	regulatory phosphorylation site [posttranslational modification]; other site
1008297012460	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1008297012461	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1008297012462	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1008297012463	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1008297012464	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297012465	active site
1008297012466	phosphorylation site [posttranslational modification]
1008297012467	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
1008297012468	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1008297012469	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1008297012470	active site
1008297012471	P-loop; other site
1008297012472	phosphorylation site [posttranslational modification]
1008297012473	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
1008297012474	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1008297012475	dimer interface [polypeptide binding]; other site
1008297012476	active site
1008297012477	glycine loop; other site
1008297012478	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297012479	FeS/SAM binding site; other site
1008297012480	pyruvate formate lyase II activase; Provisional; Region: PRK10076
1008297012481	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1008297012482	active site
1008297012483	P-loop; other site
1008297012484	phosphorylation site [posttranslational modification]
1008297012485	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1008297012486	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297012487	hypothetical protein; Provisional; Region: PRK10649
1008297012488	Sulfatase; Region: Sulfatase; pfam00884
1008297012489	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1008297012490	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1008297012491	acetylornithine deacetylase; Provisional; Region: PRK05111
1008297012492	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1008297012493	metal binding site [ion binding]; metal-binding site
1008297012494	putative dimer interface [polypeptide binding]; other site
1008297012495	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1008297012496	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1008297012497	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1008297012498	nucleotide binding site [chemical binding]; other site
1008297012499	N-acetyl-L-glutamate binding site [chemical binding]; other site
1008297012500	argininosuccinate lyase; Provisional; Region: PRK04833
1008297012501	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1008297012502	active sites [active]
1008297012503	tetramer interface [polypeptide binding]; other site
1008297012504	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1008297012505	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297012506	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1008297012507	dimerization interface [polypeptide binding]; other site
1008297012508	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1008297012509	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1008297012510	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1008297012511	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1008297012512	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297012513	hypothetical protein; Provisional; Region: PRK11056
1008297012514	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1008297012515	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
1008297012516	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297012517	S-adenosylmethionine binding site [chemical binding]; other site
1008297012518	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1008297012519	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1008297012520	N-terminal plug; other site
1008297012521	ligand-binding site [chemical binding]; other site
1008297012522	glutamate racemase; Provisional; Region: PRK00865
1008297012523	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1008297012524	FAD binding domain; Region: FAD_binding_4; pfam01565
1008297012525	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1008297012526	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1008297012527	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1008297012528	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1008297012529	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1008297012530	pantothenate kinase; Provisional; Region: PRK05439
1008297012531	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1008297012532	ATP-binding site [chemical binding]; other site
1008297012533	CoA-binding site [chemical binding]; other site
1008297012534	Mg2+-binding site [ion binding]; other site
1008297012535	elongation factor Tu; Reviewed; Region: PRK00049
1008297012536	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1008297012537	G1 box; other site
1008297012538	GEF interaction site [polypeptide binding]; other site
1008297012539	GTP/Mg2+ binding site [chemical binding]; other site
1008297012540	Switch I region; other site
1008297012541	G2 box; other site
1008297012542	G3 box; other site
1008297012543	Switch II region; other site
1008297012544	G4 box; other site
1008297012545	G5 box; other site
1008297012546	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1008297012547	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1008297012548	Antibiotic Binding Site [chemical binding]; other site
1008297012549	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1008297012550	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1008297012551	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1008297012552	putative homodimer interface [polypeptide binding]; other site
1008297012553	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1008297012554	heterodimer interface [polypeptide binding]; other site
1008297012555	homodimer interface [polypeptide binding]; other site
1008297012556	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1008297012557	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1008297012558	L7/L12 interface [polypeptide binding]; other site
1008297012559	23S rRNA interface [nucleotide binding]; other site
1008297012560	L25 interface [polypeptide binding]; other site
1008297012561	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1008297012562	mRNA/rRNA interface [nucleotide binding]; other site
1008297012563	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1008297012564	23S rRNA interface [nucleotide binding]; other site
1008297012565	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1008297012566	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1008297012567	core dimer interface [polypeptide binding]; other site
1008297012568	peripheral dimer interface [polypeptide binding]; other site
1008297012569	L10 interface [polypeptide binding]; other site
1008297012570	L11 interface [polypeptide binding]; other site
1008297012571	putative EF-Tu interaction site [polypeptide binding]; other site
1008297012572	putative EF-G interaction site [polypeptide binding]; other site
1008297012573	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1008297012574	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1008297012575	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1008297012576	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1008297012577	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1008297012578	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1008297012579	RPB3 interaction site [polypeptide binding]; other site
1008297012580	RPB1 interaction site [polypeptide binding]; other site
1008297012581	RPB11 interaction site [polypeptide binding]; other site
1008297012582	RPB10 interaction site [polypeptide binding]; other site
1008297012583	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1008297012584	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1008297012585	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1008297012586	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1008297012587	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1008297012588	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1008297012589	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1008297012590	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1008297012591	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1008297012592	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1008297012593	DNA binding site [nucleotide binding]
1008297012594	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1008297012595	type III secretion system protein; Provisional; Region: PRK15384
1008297012596	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
1008297012597	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1008297012598	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297012599	FeS/SAM binding site; other site
1008297012600	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1008297012601	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1008297012602	ThiS interaction site; other site
1008297012603	putative active site [active]
1008297012604	tetramer interface [polypeptide binding]; other site
1008297012605	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1008297012606	thiS-thiF/thiG interaction site; other site
1008297012607	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1008297012608	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1008297012609	ATP binding site [chemical binding]; other site
1008297012610	substrate interface [chemical binding]; other site
1008297012611	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1008297012612	thiamine phosphate binding site [chemical binding]; other site
1008297012613	active site
1008297012614	pyrophosphate binding site [ion binding]; other site
1008297012615	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1008297012616	ThiC-associated domain; Region: ThiC-associated; pfam13667
1008297012617	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1008297012618	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
1008297012619	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1008297012620	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1008297012621	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1008297012622	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1008297012623	putative NADH binding site [chemical binding]; other site
1008297012624	putative active site [active]
1008297012625	nudix motif; other site
1008297012626	putative metal binding site [ion binding]; other site
1008297012627	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1008297012628	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1008297012629	substrate binding site [chemical binding]; other site
1008297012630	active site
1008297012631	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1008297012632	Active_site [active]
1008297012633	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1008297012634	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1008297012635	IHF dimer interface [polypeptide binding]; other site
1008297012636	IHF - DNA interface [nucleotide binding]; other site
1008297012637	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1008297012638	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1008297012639	dimer interface [polypeptide binding]; other site
1008297012640	sensor protein ZraS; Provisional; Region: PRK10364
1008297012641	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297012642	dimer interface [polypeptide binding]; other site
1008297012643	phosphorylation site [posttranslational modification]
1008297012644	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297012645	ATP binding site [chemical binding]; other site
1008297012646	Mg2+ binding site [ion binding]; other site
1008297012647	G-X-G motif; other site
1008297012648	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
1008297012649	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297012650	active site
1008297012651	phosphorylation site [posttranslational modification]
1008297012652	intermolecular recognition site; other site
1008297012653	dimerization interface [polypeptide binding]; other site
1008297012654	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297012655	Walker A motif; other site
1008297012656	ATP binding site [chemical binding]; other site
1008297012657	Walker B motif; other site
1008297012658	arginine finger; other site
1008297012659	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1008297012660	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1008297012661	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1008297012662	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1008297012663	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1008297012664	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1008297012665	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1008297012666	purine monophosphate binding site [chemical binding]; other site
1008297012667	dimer interface [polypeptide binding]; other site
1008297012668	putative catalytic residues [active]
1008297012669	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1008297012670	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1008297012671	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297012672	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1008297012673	Coenzyme A binding pocket [chemical binding]; other site
1008297012674	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1008297012675	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1008297012676	proposed active site lysine [active]
1008297012677	conserved cys residue [active]
1008297012678	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1008297012679	malate synthase A; Region: malate_syn_A; TIGR01344
1008297012680	active site
1008297012681	isocitrate lyase; Provisional; Region: PRK15063
1008297012682	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1008297012683	tetramer interface [polypeptide binding]; other site
1008297012684	active site
1008297012685	Mg2+/Mn2+ binding site [ion binding]; other site
1008297012686	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1008297012687	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1008297012688	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1008297012689	transcriptional repressor IclR; Provisional; Region: PRK11569
1008297012690	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1008297012691	Bacterial transcriptional regulator; Region: IclR; pfam01614
1008297012692	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1008297012693	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1008297012694	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1008297012695	substrate binding pocket [chemical binding]; other site
1008297012696	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1008297012697	B12 binding site [chemical binding]; other site
1008297012698	cobalt ligand [ion binding]; other site
1008297012699	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1008297012700	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1008297012701	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1008297012702	peptidase E (pseudogene)
1008297012703	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1008297012704	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1008297012705	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1008297012706	RNA binding surface [nucleotide binding]; other site
1008297012707	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1008297012708	probable active site [active]
1008297012709	hypothetical protein; Provisional; Region: PRK10515
1008297012710	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1008297012711	Sodium Bile acid symporter family; Region: SBF; pfam01758
1008297012712	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1008297012713	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
1008297012714	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1008297012715	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1008297012716	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1008297012717	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1008297012718	Phage-related baseplate assembly protein [General function prediction only]; Region: COG3948
1008297012719	Phage baseplate assembly protein W [General function prediction only]; Region: COG3628
1008297012720	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1008297012721	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1008297012722	Ligand binding site; other site
1008297012723	Putative Catalytic site; other site
1008297012724	DXD motif; other site
1008297012725	Predicted membrane protein [Function unknown]; Region: COG2246
1008297012726	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1008297012727	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1008297012728	Phage protein D [General function prediction only]; Region: COG3500
1008297012729	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1008297012730	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1008297012731	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
1008297012732	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1008297012733	Phage tail tube protein FII [General function prediction only]; Region: COG3498
1008297012734	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
1008297012735	Gp37 protein; Region: Gp37; pfam09646
1008297012736	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1008297012737	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1008297012738	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1008297012739	catalytic residue [active]
1008297012740	Protein of unknown function (DUF4063); Region: DUF4063; pfam13272
1008297012741	Mor transcription activator family; Region: Mor; pfam08765
1008297012742	aspartate kinase III; Validated; Region: PRK09084
1008297012743	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1008297012744	nucleotide binding site [chemical binding]; other site
1008297012745	substrate binding site [chemical binding]; other site
1008297012746	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1008297012747	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1008297012748	dimer interface [polypeptide binding]; other site
1008297012749	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1008297012750	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1008297012751	active site
1008297012752	dimer interface [polypeptide binding]; other site
1008297012753	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1008297012754	dimer interface [polypeptide binding]; other site
1008297012755	active site
1008297012756	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1008297012757	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1008297012758	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1008297012759	Predicted membrane protein [Function unknown]; Region: COG3223
1008297012760	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1008297012761	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297012762	dimer interface [polypeptide binding]; other site
1008297012763	conserved gate region; other site
1008297012764	putative PBP binding loops; other site
1008297012765	ABC-ATPase subunit interface; other site
1008297012766	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1008297012767	dimer interface [polypeptide binding]; other site
1008297012768	conserved gate region; other site
1008297012769	putative PBP binding loops; other site
1008297012770	ABC-ATPase subunit interface; other site
1008297012771	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1008297012772	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1008297012773	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1008297012774	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1008297012775	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1008297012776	Walker A/P-loop; other site
1008297012777	ATP binding site [chemical binding]; other site
1008297012778	Q-loop/lid; other site
1008297012779	ABC transporter signature motif; other site
1008297012780	Walker B; other site
1008297012781	D-loop; other site
1008297012782	H-loop/switch region; other site
1008297012783	TOBE domain; Region: TOBE_2; pfam08402
1008297012784	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1008297012785	trimer interface; other site
1008297012786	sugar binding site [chemical binding]; other site
1008297012787	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1008297012788	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1008297012789	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1008297012790	UbiA prenyltransferase family; Region: UbiA; pfam01040
1008297012791	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1008297012792	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1008297012793	putative acyl-acceptor binding pocket; other site
1008297012794	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1008297012795	LexA repressor; Validated; Region: PRK00215
1008297012796	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1008297012797	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1008297012798	Catalytic site [active]
1008297012799	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1008297012800	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1008297012801	hypothetical protein; Provisional; Region: PRK10428
1008297012802	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1008297012803	metal binding site 2 [ion binding]; metal-binding site
1008297012804	putative DNA binding helix; other site
1008297012805	metal binding site 1 [ion binding]; metal-binding site
1008297012806	dimer interface [polypeptide binding]; other site
1008297012807	structural Zn2+ binding site [ion binding]; other site
1008297012808	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1008297012809	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1008297012810	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1008297012811	FMN binding site [chemical binding]; other site
1008297012812	active site
1008297012813	catalytic residues [active]
1008297012814	substrate binding site [chemical binding]; other site
1008297012815	phage shock protein G; Reviewed; Region: pspG; PRK09459
1008297012816	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1008297012817	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1008297012818	NADP binding site [chemical binding]; other site
1008297012819	dimer interface [polypeptide binding]; other site
1008297012820	replicative DNA helicase; Provisional; Region: PRK08006
1008297012821	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1008297012822	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1008297012823	Walker A motif; other site
1008297012824	ATP binding site [chemical binding]; other site
1008297012825	Walker B motif; other site
1008297012826	DNA binding loops [nucleotide binding]
1008297012827	alanine racemase; Reviewed; Region: alr; PRK00053
1008297012828	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1008297012829	active site
1008297012830	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1008297012831	substrate binding site [chemical binding]; other site
1008297012832	catalytic residues [active]
1008297012833	dimer interface [polypeptide binding]; other site
1008297012834	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1008297012835	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1008297012836	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297012837	homodimer interface [polypeptide binding]; other site
1008297012838	catalytic residue [active]
1008297012839	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1008297012840	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297012841	active site
1008297012842	motif I; other site
1008297012843	motif II; other site
1008297012844	Uncharacterized conserved protein [Function unknown]; Region: COG0432
1008297012845	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1008297012846	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1008297012847	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1008297012848	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1008297012849	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1008297012850	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1008297012851	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1008297012852	dimer interface [polypeptide binding]; other site
1008297012853	ssDNA binding site [nucleotide binding]; other site
1008297012854	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1008297012855	putative single-stranded DNA-binding protein; Region: PHA01740
1008297012856	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
1008297012857	Outer membrane efflux protein; Region: OEP; pfam02321
1008297012858	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1008297012859	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1008297012860	HlyD family secretion protein; Region: HlyD_3; pfam13437
1008297012861	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1008297012862	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012863	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012864	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012865	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012866	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012867	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1008297012868	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1008297012869	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012870	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1008297012871	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1008297012872	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012873	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1008297012874	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012875	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1008297012876	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1008297012877	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012878	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1008297012879	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012880	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1008297012881	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1008297012882	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012883	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1008297012884	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1008297012885	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012886	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1008297012887	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012888	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012889	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1008297012890	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012891	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012892	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012893	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012894	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012895	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1008297012896	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012897	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1008297012898	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012899	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
1008297012900	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012901	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1008297012902	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1008297012903	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297012904	Walker A/P-loop; other site
1008297012905	ATP binding site [chemical binding]; other site
1008297012906	Q-loop/lid; other site
1008297012907	ABC transporter signature motif; other site
1008297012908	Walker B; other site
1008297012909	D-loop; other site
1008297012910	H-loop/switch region; other site
1008297012911	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1008297012912	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1008297012913	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297012914	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1008297012915	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297012916	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1008297012917	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1008297012918	DNA binding residues [nucleotide binding]
1008297012919	dimer interface [polypeptide binding]; other site
1008297012920	[2Fe-2S] cluster binding site [ion binding]; other site
1008297012921	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1008297012922	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1008297012923	putative C-terminal domain interface [polypeptide binding]; other site
1008297012924	putative GSH binding site (G-site) [chemical binding]; other site
1008297012925	putative dimer interface [polypeptide binding]; other site
1008297012926	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
1008297012927	putative N-terminal domain interface [polypeptide binding]; other site
1008297012928	putative dimer interface [polypeptide binding]; other site
1008297012929	putative substrate binding pocket (H-site) [chemical binding]; other site
1008297012930	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1008297012931	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1008297012932	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1008297012933	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1008297012934	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297012935	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1008297012936	putative dimerization interface [polypeptide binding]; other site
1008297012937	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1008297012938	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1008297012939	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1008297012940	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1008297012941	Na binding site [ion binding]; other site
1008297012942	Predicted membrane protein [Function unknown]; Region: COG3162
1008297012943	acetyl-CoA synthetase; Provisional; Region: PRK00174
1008297012944	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1008297012945	active site
1008297012946	CoA binding site [chemical binding]; other site
1008297012947	acyl-activating enzyme (AAE) consensus motif; other site
1008297012948	AMP binding site [chemical binding]; other site
1008297012949	acetate binding site [chemical binding]; other site
1008297012950	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1008297012951	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
1008297012952	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1008297012953	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
1008297012954	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1008297012955	heme lyase subunit NrfE; Provisional; Region: PRK10369
1008297012956	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
1008297012957	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1008297012958	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1008297012959	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1008297012960	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1008297012961	Sel1-like repeats; Region: SEL1; smart00671
1008297012962	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297012963	molybdopterin cofactor binding site; other site
1008297012964	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1008297012965	molybdopterin cofactor binding site; other site
1008297012966	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1008297012967	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
1008297012968	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297012969	Coenzyme A binding pocket [chemical binding]; other site
1008297012970	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1008297012971	dimer interface [polypeptide binding]; other site
1008297012972	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1008297012973	hypothetical protein; Provisional; Region: PRK10220
1008297012974	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1008297012975	PhnA protein; Region: PhnA; pfam03831
1008297012976	proline/glycine betaine transporter; Provisional; Region: PRK10642
1008297012977	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297012978	putative substrate translocation pore; other site
1008297012979	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1008297012980	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1008297012981	HAMP domain; Region: HAMP; pfam00672
1008297012982	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297012983	dimer interface [polypeptide binding]; other site
1008297012984	phosphorylation site [posttranslational modification]
1008297012985	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297012986	ATP binding site [chemical binding]; other site
1008297012987	Mg2+ binding site [ion binding]; other site
1008297012988	G-X-G motif; other site
1008297012989	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1008297012990	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297012991	active site
1008297012992	phosphorylation site [posttranslational modification]
1008297012993	intermolecular recognition site; other site
1008297012994	dimerization interface [polypeptide binding]; other site
1008297012995	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297012996	DNA binding site [nucleotide binding]
1008297012997	putative metal dependent hydrolase; Provisional; Region: PRK11598
1008297012998	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1008297012999	Sulfatase; Region: Sulfatase; pfam00884
1008297013000	arginine:agmatin antiporter; Provisional; Region: PRK10644
1008297013001	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
1008297013002	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297013003	arginine decarboxylase; Provisional; Region: PRK15029
1008297013004	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1008297013005	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1008297013006	homodimer interface [polypeptide binding]; other site
1008297013007	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1008297013008	catalytic residue [active]
1008297013009	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1008297013010	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
1008297013011	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297013012	alpha-galactosidase; Provisional; Region: PRK15076
1008297013013	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1008297013014	NAD binding site [chemical binding]; other site
1008297013015	sugar binding site [chemical binding]; other site
1008297013016	divalent metal binding site [ion binding]; other site
1008297013017	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1008297013018	dimer interface [polypeptide binding]; other site
1008297013019	melibiose:sodium symporter; Provisional; Region: PRK10429
1008297013020	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1008297013021	fumarate hydratase; Provisional; Region: PRK15389
1008297013022	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1008297013023	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1008297013024	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1008297013025	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1008297013026	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1008297013027	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297013028	active site
1008297013029	phosphorylation site [posttranslational modification]
1008297013030	intermolecular recognition site; other site
1008297013031	dimerization interface [polypeptide binding]; other site
1008297013032	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1008297013033	PAS domain; Region: PAS; smart00091
1008297013034	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297013035	ATP binding site [chemical binding]; other site
1008297013036	Mg2+ binding site [ion binding]; other site
1008297013037	G-X-G motif; other site
1008297013038	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1008297013039	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1008297013040	putative [Fe4-S4] binding site [ion binding]; other site
1008297013041	putative molybdopterin cofactor binding site [chemical binding]; other site
1008297013042	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1008297013043	putative molybdopterin cofactor binding site; other site
1008297013044	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1008297013045	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1008297013046	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1008297013047	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
1008297013048	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1008297013049	SdiA-regulated; Region: SdiA-regulated; cd09971
1008297013050	putative active site [active]
1008297013051	AraC family transcriptional regulator; Provisional; Region: PRK15186
1008297013052	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297013053	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1008297013054	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297013055	Coenzyme A binding pocket [chemical binding]; other site
1008297013056	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1008297013057	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1008297013058	active site
1008297013059	putative transcriptional regulator; Provisional; Region: PRK11640
1008297013060	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1008297013061	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1008297013062	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1008297013063	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1008297013064	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1008297013065	DsbD alpha interface [polypeptide binding]; other site
1008297013066	catalytic residues [active]
1008297013067	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1008297013068	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1008297013069	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1008297013070	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1008297013071	Aspartase; Region: Aspartase; cd01357
1008297013072	active sites [active]
1008297013073	tetramer interface [polypeptide binding]; other site
1008297013074	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1008297013075	putative transporter; Provisional; Region: PRK11021
1008297013076	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1008297013077	oligomerisation interface [polypeptide binding]; other site
1008297013078	mobile loop; other site
1008297013079	roof hairpin; other site
1008297013080	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1008297013081	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1008297013082	ring oligomerisation interface [polypeptide binding]; other site
1008297013083	ATP/Mg binding site [chemical binding]; other site
1008297013084	stacking interactions; other site
1008297013085	hinge regions; other site
1008297013086	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1008297013087	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297013088	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1008297013089	FeS/SAM binding site; other site
1008297013090	elongation factor P; Validated; Region: PRK00529
1008297013091	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1008297013092	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1008297013093	RNA binding site [nucleotide binding]; other site
1008297013094	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1008297013095	RNA binding site [nucleotide binding]; other site
1008297013096	Predicted small secreted protein [Function unknown]; Region: COG5510
1008297013097	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1008297013098	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297013099	DNA binding residues [nucleotide binding]
1008297013100	dimerization interface [polypeptide binding]; other site
1008297013101	multidrug efflux system protein; Provisional; Region: PRK11431
1008297013102	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1008297013103	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1008297013104	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1008297013105	Iron-sulfur protein interface; other site
1008297013106	proximal quinone binding site [chemical binding]; other site
1008297013107	C-subunit interface; other site
1008297013108	distal quinone binding site; other site
1008297013109	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1008297013110	D-subunit interface [polypeptide binding]; other site
1008297013111	Iron-sulfur protein interface; other site
1008297013112	proximal quinone binding site [chemical binding]; other site
1008297013113	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1008297013114	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1008297013115	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1008297013116	L-aspartate oxidase; Provisional; Region: PRK06175
1008297013117	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1008297013118	poxB regulator PoxA; Provisional; Region: PRK09350
1008297013119	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1008297013120	motif 1; other site
1008297013121	dimer interface [polypeptide binding]; other site
1008297013122	active site
1008297013123	motif 2; other site
1008297013124	motif 3; other site
1008297013125	inner membrane transporter YjeM; Provisional; Region: PRK15238
1008297013126	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
1008297013127	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1008297013128	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1008297013129	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1008297013130	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1008297013131	GTPase RsgA; Reviewed; Region: PRK12288
1008297013132	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1008297013133	RNA binding site [nucleotide binding]; other site
1008297013134	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1008297013135	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1008297013136	GTP/Mg2+ binding site [chemical binding]; other site
1008297013137	G4 box; other site
1008297013138	G5 box; other site
1008297013139	G1 box; other site
1008297013140	Switch I region; other site
1008297013141	G2 box; other site
1008297013142	G3 box; other site
1008297013143	Switch II region; other site
1008297013144	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1008297013145	catalytic site [active]
1008297013146	putative active site [active]
1008297013147	putative substrate binding site [chemical binding]; other site
1008297013148	dimer interface [polypeptide binding]; other site
1008297013149	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1008297013150	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1008297013151	substrate binding pocket [chemical binding]; other site
1008297013152	membrane-bound complex binding site; other site
1008297013153	hinge residues; other site
1008297013154	epoxyqueuosine reductase; Region: TIGR00276
1008297013155	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1008297013156	putative carbohydrate kinase; Provisional; Region: PRK10565
1008297013157	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1008297013158	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1008297013159	putative substrate binding site [chemical binding]; other site
1008297013160	putative ATP binding site [chemical binding]; other site
1008297013161	ADP-binding protein; Provisional; Region: PRK10646
1008297013162	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1008297013163	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1008297013164	active site
1008297013165	metal binding site [ion binding]; metal-binding site
1008297013166	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1008297013167	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297013168	ATP binding site [chemical binding]; other site
1008297013169	Mg2+ binding site [ion binding]; other site
1008297013170	G-X-G motif; other site
1008297013171	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1008297013172	ATP binding site [chemical binding]; other site
1008297013173	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1008297013174	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1008297013175	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1008297013176	bacterial Hfq-like; Region: Hfq; cd01716
1008297013177	hexamer interface [polypeptide binding]; other site
1008297013178	Sm1 motif; other site
1008297013179	RNA binding site [nucleotide binding]; other site
1008297013180	Sm2 motif; other site
1008297013181	GTPase HflX; Provisional; Region: PRK11058
1008297013182	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1008297013183	HflX GTPase family; Region: HflX; cd01878
1008297013184	G1 box; other site
1008297013185	GTP/Mg2+ binding site [chemical binding]; other site
1008297013186	Switch I region; other site
1008297013187	G2 box; other site
1008297013188	G3 box; other site
1008297013189	Switch II region; other site
1008297013190	G4 box; other site
1008297013191	G5 box; other site
1008297013192	FtsH protease regulator HflK; Provisional; Region: PRK10930
1008297013193	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1008297013194	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1008297013195	FtsH protease regulator HflC; Provisional; Region: PRK11029
1008297013196	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1008297013197	potential frameshift: common BLAST hit: gi|379703605|ref|YP_005245333.1| adenylosuccinate synthetase
1008297013198	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1008297013199	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1008297013200	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1008297013201	IMP binding site; other site
1008297013202	transcriptional repressor NsrR; Provisional; Region: PRK11014
1008297013203	Predicted transcriptional regulator [Transcription]; Region: COG1959
1008297013204	exoribonuclease R; Provisional; Region: PRK11642
1008297013205	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1008297013206	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1008297013207	RNB domain; Region: RNB; pfam00773
1008297013208	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1008297013209	RNA binding site [nucleotide binding]; other site
1008297013210	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1008297013211	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1008297013212	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1008297013213	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3789
1008297013214	hypothetical protein (pseudogene)
1008297013215	Ion channel; Region: Ion_trans_2; pfam07885
1008297013216	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
1008297013217	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
1008297013218	Predicted membrane protein [Function unknown]; Region: COG3766
1008297013219	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1008297013220	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1008297013221	Predicted integral membrane protein [Function unknown]; Region: COG5463
1008297013222	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1008297013223	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1008297013224	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1008297013225	FAD binding site [chemical binding]; other site
1008297013226	substrate binding site [chemical binding]; other site
1008297013227	catalytic residues [active]
1008297013228	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1008297013229	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1008297013230	esterase; Provisional; Region: PRK10566
1008297013231	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1008297013232	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1008297013233	transcriptional repressor UlaR; Provisional; Region: PRK13509
1008297013234	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1008297013235	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1008297013236	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1008297013237	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1008297013238	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1008297013239	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1008297013240	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1008297013241	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297013242	active site
1008297013243	phosphorylation site [posttranslational modification]
1008297013244	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1008297013245	active site
1008297013246	dimer interface [polypeptide binding]; other site
1008297013247	magnesium binding site [ion binding]; other site
1008297013248	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1008297013249	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1008297013250	AP (apurinic/apyrimidinic) site pocket; other site
1008297013251	DNA interaction; other site
1008297013252	Metal-binding active site; metal-binding site
1008297013253	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1008297013254	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1008297013255	intersubunit interface [polypeptide binding]; other site
1008297013256	active site
1008297013257	Zn2+ binding site [ion binding]; other site
1008297013258	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1008297013259	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1008297013260	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1008297013261	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1008297013262	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1008297013263	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1008297013264	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1008297013265	EamA-like transporter family; Region: EamA; pfam00892
1008297013266	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1008297013267	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1008297013268	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1008297013269	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1008297013270	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1008297013271	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1008297013272	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1008297013273	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1008297013274	Hemerythrin-like domain; Region: Hr-like; cd12108
1008297013275	Fe binding site [ion binding]; other site
1008297013276	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1008297013277	EamA-like transporter family; Region: EamA; pfam00892
1008297013278	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1008297013279	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1008297013280	NADP binding site [chemical binding]; other site
1008297013281	Predicted transcriptional regulators [Transcription]; Region: COG1733
1008297013282	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1008297013283	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1008297013284	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1008297013285	active site
1008297013286	metal binding site [ion binding]; metal-binding site
1008297013287	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1008297013288	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1008297013289	active site
1008297013290	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
1008297013291	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1008297013292	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1008297013293	Domain of unknown function DUF21; Region: DUF21; pfam01595
1008297013294	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1008297013295	Transporter associated domain; Region: CorC_HlyC; smart01091
1008297013296	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1008297013297	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1008297013298	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1008297013299	Surface antigen; Region: Bac_surface_Ag; pfam01103
1008297013300	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1008297013301	Family of unknown function (DUF490); Region: DUF490; pfam04357
1008297013302	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1008297013303	dimerization interface [polypeptide binding]; other site
1008297013304	putative active site pocket [active]
1008297013305	putative catalytic residue [active]
1008297013306	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297013307	D-galactonate transporter; Region: 2A0114; TIGR00893
1008297013308	putative substrate translocation pore; other site
1008297013309	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
1008297013310	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1008297013311	active site
1008297013312	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1008297013313	dimer interface [polypeptide binding]; other site
1008297013314	substrate binding site [chemical binding]; other site
1008297013315	metal binding sites [ion binding]; metal-binding site
1008297013316	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1008297013317	AMP binding site [chemical binding]; other site
1008297013318	metal binding site [ion binding]; metal-binding site
1008297013319	active site
1008297013320	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1008297013321	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1008297013322	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1008297013323	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1008297013324	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1008297013325	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1008297013326	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1008297013327	putative active site [active]
1008297013328	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1008297013329	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297013330	putative substrate translocation pore; other site
1008297013331	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297013332	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1008297013333	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297013334	putative substrate translocation pore; other site
1008297013335	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297013336	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
1008297013337	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1008297013338	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1008297013339	tetrameric interface [polypeptide binding]; other site
1008297013340	NAD binding site [chemical binding]; other site
1008297013341	catalytic residues [active]
1008297013342	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1008297013343	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1008297013344	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297013345	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1008297013346	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1008297013347	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1008297013348	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1008297013349	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
1008297013350	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
1008297013351	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1008297013352	major facilitator superfamily transporter; Provisional; Region: PRK05122
1008297013353	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297013354	putative substrate translocation pore; other site
1008297013355	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1008297013356	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1008297013357	substrate binding site [chemical binding]; other site
1008297013358	ATP binding site [chemical binding]; other site
1008297013359	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
1008297013360	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
1008297013361	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
1008297013362	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1008297013363	PYR/PP interface [polypeptide binding]; other site
1008297013364	dimer interface [polypeptide binding]; other site
1008297013365	TPP binding site [chemical binding]; other site
1008297013366	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1008297013367	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
1008297013368	TPP-binding site; other site
1008297013369	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1008297013370	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1008297013371	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1008297013372	polyol permease family; Region: 2A0118; TIGR00897
1008297013373	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297013374	putative substrate translocation pore; other site
1008297013375	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
1008297013376	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1008297013377	DNA interaction; other site
1008297013378	Metal-binding active site; metal-binding site
1008297013379	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1008297013380	hypothetical protein; Provisional; Region: PRK05255
1008297013381	peptidase PmbA; Provisional; Region: PRK11040
1008297013382	cytochrome b562; Provisional; Region: PRK15058
1008297013383	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1008297013384	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
1008297013385	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
1008297013386	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1008297013387	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
1008297013388	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
1008297013389	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1008297013390	active site
1008297013391	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1008297013392	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1008297013393	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1008297013394	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1008297013395	HTH domain; Region: HTH_11; pfam08279
1008297013396	Mga helix-turn-helix domain; Region: Mga; pfam05043
1008297013397	PRD domain; Region: PRD; pfam00874
1008297013398	PRD domain; Region: PRD; pfam00874
1008297013399	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1008297013400	active site
1008297013401	P-loop; other site
1008297013402	phosphorylation site [posttranslational modification]
1008297013403	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1008297013404	active site
1008297013405	phosphorylation site [posttranslational modification]
1008297013406	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
1008297013407	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1008297013408	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297013409	4Fe-4S single cluster domain; Region: Fer4_14; pfam13394
1008297013410	FeS/SAM binding site; other site
1008297013411	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1008297013412	ATP cone domain; Region: ATP-cone; pfam03477
1008297013413	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1008297013414	effector binding site; other site
1008297013415	active site
1008297013416	Zn binding site [ion binding]; other site
1008297013417	glycine loop; other site
1008297013418	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1008297013419	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1008297013420	Ca binding site [ion binding]; other site
1008297013421	active site
1008297013422	catalytic site [active]
1008297013423	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1008297013424	PTS system, trehalose-specific IIBC component (pseudogene)
1008297013425	trehalose repressor; Provisional; Region: treR; PRK09492
1008297013426	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297013427	DNA binding site [nucleotide binding]
1008297013428	domain linker motif; other site
1008297013429	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1008297013430	dimerization interface [polypeptide binding]; other site
1008297013431	ligand binding site [chemical binding]; other site
1008297013432	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1008297013433	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1008297013434	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1008297013435	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1008297013436	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1008297013437	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1008297013438	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1008297013439	Transposase; Region: HTH_Tnp_1; cl17663
1008297013440	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1008297013441	homotrimer interaction site [polypeptide binding]; other site
1008297013442	putative active site [active]
1008297013443	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1008297013444	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1008297013445	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1008297013446	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1008297013447	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1008297013448	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1008297013449	Arginine repressor [Transcription]; Region: ArgR; COG1438
1008297013450	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1008297013451	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1008297013452	Predicted membrane protein [Function unknown]; Region: COG1288
1008297013453	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1008297013454	ornithine carbamoyltransferase; Validated; Region: PRK02102
1008297013455	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1008297013456	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1008297013457	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1008297013458	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1008297013459	putative substrate binding site [chemical binding]; other site
1008297013460	nucleotide binding site [chemical binding]; other site
1008297013461	nucleotide binding site [chemical binding]; other site
1008297013462	homodimer interface [polypeptide binding]; other site
1008297013463	arginine deiminase; Provisional; Region: PRK01388
1008297013464	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1008297013465	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1008297013466	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1008297013467	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1008297013468	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
1008297013469	RNase E inhibitor protein; Provisional; Region: PRK11191
1008297013470	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1008297013471	active site
1008297013472	dinuclear metal binding site [ion binding]; other site
1008297013473	dimerization interface [polypeptide binding]; other site
1008297013474	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
1008297013475	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1008297013476	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297013477	Coenzyme A binding pocket [chemical binding]; other site
1008297013478	Predicted membrane protein [Function unknown]; Region: COG4269
1008297013479	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1008297013480	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1008297013481	HIGH motif; other site
1008297013482	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1008297013483	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1008297013484	active site
1008297013485	KMSKS motif; other site
1008297013486	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1008297013487	tRNA binding surface [nucleotide binding]; other site
1008297013488	anticodon binding site; other site
1008297013489	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1008297013490	DNA polymerase III subunit chi; Validated; Region: PRK05728
1008297013491	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1008297013492	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1008297013493	interface (dimer of trimers) [polypeptide binding]; other site
1008297013494	Substrate-binding/catalytic site; other site
1008297013495	Zn-binding sites [ion binding]; other site
1008297013496	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1008297013497	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1008297013498	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1008297013499	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1008297013500	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1008297013501	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1008297013502	DNA binding site [nucleotide binding]
1008297013503	domain linker motif; other site
1008297013504	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1008297013505	putative dimerization interface [polypeptide binding]; other site
1008297013506	putative ligand binding site [chemical binding]; other site
1008297013507	gluconate transporter; Region: gntP; TIGR00791
1008297013508	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1008297013509	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
1008297013510	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1008297013511	NADP binding site [chemical binding]; other site
1008297013512	homodimer interface [polypeptide binding]; other site
1008297013513	active site
1008297013514	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1008297013515	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1008297013516	putative NAD(P) binding site [chemical binding]; other site
1008297013517	catalytic Zn binding site [ion binding]; other site
1008297013518	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1008297013519	ATP-binding site [chemical binding]; other site
1008297013520	Gluconate-6-phosphate binding site [chemical binding]; other site
1008297013521	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1008297013522	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1008297013523	putative NAD(P) binding site [chemical binding]; other site
1008297013524	putative substrate binding site [chemical binding]; other site
1008297013525	catalytic Zn binding site [ion binding]; other site
1008297013526	structural Zn binding site [ion binding]; other site
1008297013527	dimer interface [polypeptide binding]; other site
1008297013528	Part of AAA domain; Region: AAA_19; pfam13245
1008297013529	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1008297013530	AAA domain; Region: AAA_12; pfam13087
1008297013531	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1008297013532	putative active site [active]
1008297013533	catalytic site [active]
1008297013534	Uncharacterized conserved protein [Function unknown]; Region: COG4127
1008297013535	Restriction endonuclease; Region: Mrr_cat; pfam04471
1008297013536	conserved hypothetical protein; Region: Lon_rel_chp; TIGR02653
1008297013537	Putative ATP-dependent Lon protease; Region: Lon_2; pfam13337
1008297013538	TIGR02687 family protein; Region: TIGR02687
1008297013539	PglZ domain; Region: PglZ; pfam08665
1008297013540	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297013541	AAA domain; Region: AAA_21; pfam13304
1008297013542	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297013543	Walker A/P-loop; other site
1008297013544	Walker A/P-loop; other site
1008297013545	ATP binding site [chemical binding]; other site
1008297013546	ATP binding site [chemical binding]; other site
1008297013547	Q-loop/lid; other site
1008297013548	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
1008297013549	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1008297013550	TIGR02680 family protein; Region: TIGR02680
1008297013551	Domain of unknown function (DUF1788); Region: DUF1788; pfam08747
1008297013552	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
1008297013553	hypothetical protein; Provisional; Region: PRK12378
1008297013554	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1008297013555	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297013556	S-adenosylmethionine binding site [chemical binding]; other site
1008297013557	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1008297013558	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297013559	S-adenosylmethionine binding site [chemical binding]; other site
1008297013560	hypothetical protein; Provisional; Region: PRK13687
1008297013561	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1008297013562	Protein of unknown function DUF91; Region: DUF91; cl00709
1008297013563	Uncharacterized conserved protein [Function unknown]; Region: COG3439
1008297013564	Dienelactone hydrolase family; Region: DLH; pfam01738
1008297013565	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1008297013566	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1008297013567	DNA-binding site [nucleotide binding]; DNA binding site
1008297013568	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1008297013569	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1008297013570	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1008297013571	active site
1008297013572	HIGH motif; other site
1008297013573	dimer interface [polypeptide binding]; other site
1008297013574	KMSKS motif; other site
1008297013575	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1008297013576	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
1008297013577	aspartate racemase; Region: asp_race; TIGR00035
1008297013578	cell density-dependent motility repressor; Provisional; Region: PRK10082
1008297013579	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297013580	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1008297013581	dimerization interface [polypeptide binding]; other site
1008297013582	isoaspartyl dipeptidase; Provisional; Region: PRK10657
1008297013583	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1008297013584	active site
1008297013585	hypothetical protein; Provisional; Region: PRK10519
1008297013586	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1008297013587	Nucleoside recognition; Region: Gate; pfam07670
1008297013588	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
1008297013589	Predicted membrane protein [Function unknown]; Region: COG2733
1008297013590	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
1008297013591	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1008297013592	putative substrate translocation pore; other site
1008297013593	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1008297013594	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1008297013595	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1008297013596	NAD(P) binding site [chemical binding]; other site
1008297013597	catalytic residues [active]
1008297013598	endoribonuclease SymE; Provisional; Region: PRK13605
1008297013599	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1008297013600	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1008297013601	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1008297013602	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1008297013603	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1008297013604	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
1008297013605	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
1008297013606	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1008297013607	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1008297013608	ATP binding site [chemical binding]; other site
1008297013609	putative Mg++ binding site [ion binding]; other site
1008297013610	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
1008297013611	Mrr N-terminal domain; Region: Mrr_N; pfam14338
1008297013612	Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; Region: CH; cl00030
1008297013613	Restriction endonuclease; Region: Mrr_cat; pfam04471
1008297013614	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
1008297013615	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
1008297013616	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1008297013617	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1008297013618	P-loop, Walker A motif; other site
1008297013619	Base recognition motif; other site
1008297013620	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1008297013621	Uncharacterized small protein [Function unknown]; Region: COG2879
1008297013622	carbon starvation protein A; Provisional; Region: PRK15015
1008297013623	Carbon starvation protein CstA; Region: CstA; pfam02554
1008297013624	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1008297013625	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1008297013626	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1008297013627	dimer interface [polypeptide binding]; other site
1008297013628	ligand binding site [chemical binding]; other site
1008297013629	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1008297013630	dimerization interface [polypeptide binding]; other site
1008297013631	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1008297013632	dimer interface [polypeptide binding]; other site
1008297013633	putative CheW interface [polypeptide binding]; other site
1008297013634	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1008297013635	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297013636	Walker A motif; other site
1008297013637	ATP binding site [chemical binding]; other site
1008297013638	Walker B motif; other site
1008297013639	arginine finger; other site
1008297013640	Transcriptional antiterminator [Transcription]; Region: COG3933
1008297013641	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1008297013642	active pocket/dimerization site; other site
1008297013643	active site
1008297013644	phosphorylation site [posttranslational modification]
1008297013645	PRD domain; Region: PRD; pfam00874
1008297013646	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1008297013647	active pocket/dimerization site; other site
1008297013648	active site
1008297013649	phosphorylation site [posttranslational modification]
1008297013650	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1008297013651	active site
1008297013652	phosphorylation site [posttranslational modification]
1008297013653	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1008297013654	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1008297013655	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1008297013656	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1008297013657	dimer interface [polypeptide binding]; other site
1008297013658	active site
1008297013659	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1008297013660	dimer interface [polypeptide binding]; other site
1008297013661	active site
1008297013662	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1008297013663	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1008297013664	putative active site [active]
1008297013665	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1008297013666	phosphoglycerol transferase I; Provisional; Region: PRK03776
1008297013667	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1008297013668	hypothetical protein; Provisional; Region: PRK11667
1008297013669	DNA replication protein DnaC; Validated; Region: PRK07952
1008297013670	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1008297013671	Walker A motif; other site
1008297013672	ATP binding site [chemical binding]; other site
1008297013673	Walker B motif; other site
1008297013674	primosomal protein DnaI; Provisional; Region: PRK02854
1008297013675	hypothetical protein; Provisional; Region: PRK09917
1008297013676	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1008297013677	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1008297013678	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1008297013679	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297013680	DNA binding residues [nucleotide binding]
1008297013681	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1008297013682	putative deacylase active site [active]
1008297013683	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1008297013684	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1008297013685	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1008297013686	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1008297013687	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1008297013688	metal binding site [ion binding]; metal-binding site
1008297013689	active site
1008297013690	I-site; other site
1008297013691	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1008297013692	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1008297013693	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1008297013694	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1008297013695	S-adenosylmethionine binding site [chemical binding]; other site
1008297013696	DNA polymerase III subunit psi; Validated; Region: PRK06856
1008297013697	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1008297013698	Coenzyme A binding pocket [chemical binding]; other site
1008297013699	dUMP phosphatase; Provisional; Region: PRK09449
1008297013700	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297013701	motif II; other site
1008297013702	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1008297013703	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1008297013704	G1 box; other site
1008297013705	putative GEF interaction site [polypeptide binding]; other site
1008297013706	GTP/Mg2+ binding site [chemical binding]; other site
1008297013707	Switch I region; other site
1008297013708	G2 box; other site
1008297013709	G3 box; other site
1008297013710	Switch II region; other site
1008297013711	G4 box; other site
1008297013712	G5 box; other site
1008297013713	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1008297013714	periplasmic protein; Provisional; Region: PRK10568
1008297013715	BON domain; Region: BON; pfam04972
1008297013716	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1008297013717	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1008297013718	active site
1008297013719	nucleophile elbow; other site
1008297013720	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1008297013721	active site
1008297013722	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
1008297013723	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1008297013724	FeS/SAM binding site; other site
1008297013725	hypothetical protein; Provisional; Region: PRK10977
1008297013726	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1008297013727	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1008297013728	intersubunit interface [polypeptide binding]; other site
1008297013729	active site
1008297013730	catalytic residue [active]
1008297013731	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1008297013732	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1008297013733	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1008297013734	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1008297013735	phosphopentomutase; Provisional; Region: PRK05362
1008297013736	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1008297013737	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1008297013738	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1008297013739	hypothetical protein; Provisional; Region: PRK15301
1008297013740	putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304
1008297013741	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297013742	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297013743	PapC C-terminal domain; Region: PapC_C; pfam13953
1008297013744	putative fimbrial chaperone protein; Provisional; Region: PRK09918
1008297013745	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297013746	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297013747	hypothetical protein; Provisional; Region: PRK15302
1008297013748	hypothetical protein; Provisional; Region: PRK15303
1008297013749	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1008297013750	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1008297013751	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1008297013752	hypothetical protein; Provisional; Region: PRK11246
1008297013753	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1008297013754	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1008297013755	motif II; other site
1008297013756	DNA repair protein RadA; Region: sms; TIGR00416
1008297013757	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1008297013758	Walker A motif/ATP binding site; other site
1008297013759	ATP binding site [chemical binding]; other site
1008297013760	Walker B motif; other site
1008297013761	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1008297013762	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1008297013763	non-specific DNA binding site [nucleotide binding]; other site
1008297013764	salt bridge; other site
1008297013765	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1008297013766	sequence-specific DNA binding site [nucleotide binding]; other site
1008297013767	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1008297013768	active site
1008297013769	(T/H)XGH motif; other site
1008297013770	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1008297013771	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1008297013772	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1008297013773	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1008297013774	ABC transporter; Region: ABC_tran_2; pfam12848
1008297013775	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1008297013776	lytic murein transglycosylase; Provisional; Region: PRK11619
1008297013777	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1008297013778	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1008297013779	catalytic residue [active]
1008297013780	Trp operon repressor; Provisional; Region: PRK01381
1008297013781	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1008297013782	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1008297013783	catalytic core [active]
1008297013784	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1008297013785	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297013786	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1008297013787	hypothetical protein; Provisional; Region: PRK10756
1008297013788	CreA protein; Region: CreA; pfam05981
1008297013789	DNA-binding response regulator CreB; Provisional; Region: PRK11083
1008297013790	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297013791	active site
1008297013792	phosphorylation site [posttranslational modification]
1008297013793	intermolecular recognition site; other site
1008297013794	dimerization interface [polypeptide binding]; other site
1008297013795	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297013796	DNA binding site [nucleotide binding]
1008297013797	sensory histidine kinase CreC; Provisional; Region: PRK11100
1008297013798	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1008297013799	dimerization interface [polypeptide binding]; other site
1008297013800	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1008297013801	dimer interface [polypeptide binding]; other site
1008297013802	phosphorylation site [posttranslational modification]
1008297013803	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1008297013804	ATP binding site [chemical binding]; other site
1008297013805	Mg2+ binding site [ion binding]; other site
1008297013806	G-X-G motif; other site
1008297013807	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
1008297013808	putative major fimbrial protein SthE; Provisional; Region: PRK15292
1008297013809	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1008297013810	putative fimbrial protein SthD; Provisional; Region: PRK15293
1008297013811	putative fimbrial outer membrane usher protein SthC; Provisional; Region: PRK15294
1008297013812	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297013813	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297013814	PapC C-terminal domain; Region: PapC_C; pfam13953
1008297013815	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
1008297013816	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297013817	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297013818	putative fimbrial protein SthA; Provisional; Region: PRK15296
1008297013819	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1008297013820	Helix-turn-helix domain; Region: HTH_36; pfam13730
1008297013821	putative secreted protein (pseudogene)
1008297013822	two-component response regulator; Provisional; Region: PRK11173
1008297013823	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1008297013824	active site
1008297013825	phosphorylation site [posttranslational modification]
1008297013826	intermolecular recognition site; other site
1008297013827	dimerization interface [polypeptide binding]; other site
1008297013828	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1008297013829	DNA binding site [nucleotide binding]
1008297013830	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1008297013831	putative RNA methyltransferase; Provisional; Region: PRK10433
1008297013832	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1008297013833	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
1008297013834	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1008297013835	putative active site [active]
1008297013836	catalytic site [active]
1008297013837	replication protein; Provisional; Region: PRK13750
1008297013838	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1008297013839	SdiA-regulated; Region: SdiA-regulated; cd09971
1008297013840	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1008297013841	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1008297013842	resistance to complement killing; Provisional; Region: PRK15240
1008297013843	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1008297013844	SdiA-regulated; Region: SdiA-regulated; cd09971
1008297013845	putative active site [active]
1008297013846	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1008297013847	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1008297013848	catalytic residues [active]
1008297013849	hinge region; other site
1008297013850	alpha helical domain; other site
1008297013851	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1008297013852	DNA binding residues [nucleotide binding]
1008297013853	dimerization interface [polypeptide binding]; other site
1008297013854	FaeA-like protein; Region: FaeA; pfam04703
1008297013855	fimbrial chaperone protein PefD; Provisional; Region: PRK15211
1008297013856	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1008297013857	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1008297013858	fimbrial outer membrane usher protein PefC; Provisional; Region: PRK15213
1008297013859	PapC N-terminal domain; Region: PapC_N; pfam13954
1008297013860	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1008297013861	fimbrial protein PefA; Provisional; Region: PRK15214
1008297013862	Adhesin biosynthesis transcription regulatory protein; Region: PapB; pfam03333
1008297013863	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1008297013864	Post-segregation antitoxin CcdA; Region: CcdA; cl02188
1008297013865	CcdB protein; Region: CcdB; cl03380
1008297013866	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1008297013867	active site
1008297013868	catalytic residues [active]
1008297013869	DNA binding site [nucleotide binding]
1008297013870	Int/Topo IB signature motif; other site
1008297013871	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1008297013872	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1008297013873	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1008297013874	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1008297013875	Salmonella plasmid virulence protein SpvD; Region: SpvD; cl05237
1008297013876	Salmonella virulence-associated 28kDa protein; Region: VRP3; cl04142
1008297013877	virulence protein SpvB; Provisional; Region: PRK15244
1008297013878	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
1008297013879	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
1008297013880	active site
1008297013881	conformational flexibility of ligand binding pocket; other site
1008297013882	ADP-ribosylating toxin turn-turn motif; other site
1008297013883	virulence protein SpvA; Provisional; Region: PRK15212
1008297013884	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1008297013885	transcriptional regulator SpvR; Provisional; Region: PRK15243
1008297013886	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1008297013887	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1008297013888	Homeodomain-like domain; Region: HTH_23; pfam13384
1008297013889	Winged helix-turn helix; Region: HTH_29; pfam13551
1008297013890	Homeodomain-like domain; Region: HTH_32; pfam13565
1008297013891	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
1008297013892	DDE superfamily endonuclease; Region: DDE_3; pfam13358
1008297013893	Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]; Region: ExeA; COG3267
1008297013894	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1008297013895	Walker A/P-loop; other site
1008297013896	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1008297013897	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1008297013898	catalytic residues [active]
1008297013899	catalytic nucleophile [active]
1008297013900	Presynaptic Site I dimer interface [polypeptide binding]; other site
1008297013901	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1008297013902	Synaptic Flat tetramer interface [polypeptide binding]; other site
1008297013903	Synaptic Site I dimer interface [polypeptide binding]; other site
1008297013904	DNA binding site [nucleotide binding]
1008297013905	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
1008297013906	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
1008297013907	active site clefts [active]
1008297013908	zinc binding site [ion binding]; other site
1008297013909	dimer interface [polypeptide binding]; other site
1008297013910	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1008297013911	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1008297013912	catalytic site [active]
1008297013913	Protein of unknown function (DUF2913); Region: DUF2913; pfam11140
1008297013914	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1008297013915	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1008297013916	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1008297013917	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1008297013918	P-loop; other site
1008297013919	Magnesium ion binding site [ion binding]; other site
1008297013920	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1008297013921	Magnesium ion binding site [ion binding]; other site
1008297013922	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1008297013923	ParB-like nuclease domain; Region: ParBc; pfam02195
1008297013924	ParB family; Region: ParB; pfam08775
1008297013925	potential frameshift: common BLAST hit: gi|379699154|ref|YP_005245624.1| mutagenesis protein
1008297013926	Y-family of DNA polymerases; Region: PolY; cl12025
1008297013927	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1008297013928	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1008297013929	active site
1008297013930	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1008297013931	Catalytic site [active]
1008297013932	putative methylase; Provisional; Region: PRK13699
1008297013933	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1008297013934	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
1008297013935	Antirestriction protein; Region: Antirestrict; pfam03230
1008297013936	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
1008297013937	DNA polymerase III, theta subunit; Region: DNA_pol3_theta; pfam06440
1008297013938	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1008297013939	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1008297013940	dimer interface [polypeptide binding]; other site
1008297013941	ssDNA binding site [nucleotide binding]; other site
1008297013942	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1008297013943	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1008297013944	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1008297013945	ParB-like nuclease domain; Region: ParBc; pfam02195
1008297013946	Plasmid SOS inhibition protein (PsiB); Region: PsiB; pfam06290
1008297013947	PsiA protein; Region: PsiA; pfam06952
1008297013948	Domain of unknown function (DUF932); Region: DUF932; cl12129
1008297013949	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1008297013950	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1008297013951	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1008297013952	catalytic residue [active]
1008297013953	conjugal transfer protein TraM; Provisional; Region: PRK13713
1008297013954	conjugal transfer pilin subunit TraA; Provisional; Region: PRK13734
1008297013955	conjugal transfer pilus assembly protein TraL; Provisional; Region: PRK13707
1008297013956	conjugal transfer pilus assembly protein TraE; Provisional; Region: PRK13726
1008297013957	conjugal transfer protein TraK; Provisional; Region: PRK13736
1008297013958	TraK protein; Region: TraK; pfam06586
1008297013959	conjugal transfer pilus assembly protein TraB; Provisional; Region: PRK13729
1008297013960	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
1008297013961	TraP protein; Region: TraP; pfam07296
1008297013962	conjugal transfer protein TrbD; Provisional; Region: PRK13724
1008297013963	NTPase; Region: NTPase_1; cl17478
1008297013964	conjugal transfer protein TraV; Provisional; Region: PRK13733
1008297013965	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
1008297013966	conjugal transfer protein TraR; Provisional; Region: PRK13715
1008297013967	conjugal transfer ATP-binding protein TraC; Provisional; Region: PRK13721
1008297013968	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
1008297013969	Domain of unknown function DUF87; Region: DUF87; pfam01935
1008297013970	conjugal transfer protein TrbI; Provisional; Region: PRK13717
1008297013971	conjugal transfer pilus assembly protein TraW; Provisional; Region: PRK13738
1008297013972	conjugal transfer pilus assembly protein TraU; Provisional; Region: PRK13737
1008297013973	conjugal transfer pilus assembly protein TrbC; Provisional; Region: PRK13730
1008297013974	type-F conjugative transfer system mating-pair stabilization protein TraN; Region: TraN_Ftype; TIGR02750
1008297013975	Conjugal transfer protein TrbE; Region: TrbE; cl10142
1008297013976	conjugal pilus assembly protein TraF; Provisional; Region: PRK13703
1008297013977	F plasmid transfer operon protein; Region: TraF; pfam13728
1008297013978	conjugal transfer pilin chaperone TraQ; Provisional; Region: PRK13727
1008297013979	conjugal transfer protein TrbB; Provisional; Region: PRK13728
1008297013980	conjugal transfer pilus assembly protein TraH; Provisional; Region: PRK13723
1008297013981	conjugal transfer mating pair stabilization protein TraG; Provisional; Region: PRK13735
1008297013982	Plasmid conjugative transfer entry exclusion protein TraS; Region: TraS; pfam10624
1008297013983	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
1008297013984	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
1008297013985	conjugal transfer protein TraD; Provisional; Region: PRK13700
1008297013986	F sex factor protein N terminal; Region: TraD_N; pfam12615
1008297013987	Bacterial conjugation protein TrwB,  ATP binding domain. TrwB is a homohexamer encoded by conjugative plasmids in Gram-negative bacteria. TrwB also has an all alpha domain which has been hypothesized to be responsible for DNA binding. TrwB is a component...; Region: TrwB; cd01127
1008297013988	multimer interface [polypeptide binding]; other site
1008297013989	Walker A motif; other site
1008297013990	ATP binding site [chemical binding]; other site
1008297013991	Walker B motif; other site
1008297013992	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1008297013993	oligomeric interface; other site
1008297013994	putative active site [active]
1008297013995	homodimer interface [polypeptide binding]; other site
1008297013996	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1008297013997	potential frameshift: common BLAST hit: gi|379699103|ref|YP_005245573.1| conjugative transfer oriT nicking-unwinding protein
1008297013998	TrwC relaxase; Region: TrwC; pfam08751
1008297013999	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
1008297014000	ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member [DNA replication, recombination, and repair]; Region: RecD; COG0507
1008297014001	AAA domain; Region: AAA_30; pfam13604
1008297014002	DNA helicase TraI; Region: TraI; pfam07057
1008297014003	conjugal transfer pilus acetylation protein TraX; Provisional; Region: PRK13706
1008297014004	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
1008297014005	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
1008297014006	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
1008297014007	putative kissing complex interaction region; other site
1008297014008	putative RNA binding sites [nucleotide binding]; other site