-- dump date   	20140620_055203
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
568709000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
568709000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
568709000003	putative catalytic residues [active]
568709000004	putative nucleotide binding site [chemical binding]; other site
568709000005	putative aspartate binding site [chemical binding]; other site
568709000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
568709000007	dimer interface [polypeptide binding]; other site
568709000008	putative threonine allosteric regulatory site; other site
568709000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
568709000010	putative threonine allosteric regulatory site; other site
568709000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
568709000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
568709000013	homoserine kinase; Provisional; Region: PRK01212
568709000014	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
568709000015	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
568709000016	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
568709000017	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709000018	catalytic residue [active]
568709000019	hypothetical protein; Validated; Region: PRK02101
568709000020	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
568709000021	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
568709000022	transaldolase-like protein; Provisional; Region: PTZ00411
568709000023	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
568709000024	active site
568709000025	dimer interface [polypeptide binding]; other site
568709000026	catalytic residue [active]
568709000027	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
568709000028	MPT binding site; other site
568709000029	trimer interface [polypeptide binding]; other site
568709000030	hypothetical protein; Provisional; Region: PRK10659
568709000031	hypothetical protein; Provisional; Region: PRK10236
568709000032	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
568709000033	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
568709000034	Protein of unknown function (DUF2541); Region: DUF2541; pfam10807
568709000035	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
568709000036	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
568709000037	nucleotide binding site [chemical binding]; other site
568709000038	chaperone protein DnaJ; Provisional; Region: PRK10767
568709000039	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
568709000040	HSP70 interaction site [polypeptide binding]; other site
568709000041	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
568709000042	substrate binding site [polypeptide binding]; other site
568709000043	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
568709000044	Zn binding sites [ion binding]; other site
568709000045	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
568709000046	dimer interface [polypeptide binding]; other site
568709000047	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709000048	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709000049	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
568709000050	substrate binding pocket [chemical binding]; other site
568709000051	dimerization interface [polypeptide binding]; other site
568709000052	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
568709000053	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
568709000054	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
568709000055	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
568709000056	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
568709000057	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
568709000058	active site
568709000059	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
568709000060	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
568709000061	aromatic chitin/cellulose binding site residues [chemical binding]; other site
568709000062	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
568709000063	Helix-turn-helix domain; Region: HTH_36; pfam13730
568709000064	fimbrial protein BcfA; Provisional; Region: PRK15187
568709000065	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
568709000066	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709000067	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709000068	outer membrane usher protein; Provisional; Region: PRK15193
568709000069	PapC N-terminal domain; Region: PapC_N; pfam13954
568709000070	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709000071	PapC C-terminal domain; Region: PapC_C; pfam13953
568709000072	fimbrial protein BcfD; Provisional; Region: PRK15189
568709000073	fimbrial protein BcfE; Provisional; Region: PRK15190
568709000074	fimbrial protein BcfF; Provisional; Region: PRK15191
568709000075	fimbrial chaperone BcfG; Provisional; Region: PRK15192
568709000076	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709000077	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709000078	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
568709000079	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
568709000080	catalytic residues [active]
568709000081	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
568709000082	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709000083	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709000084	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709000085	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
568709000086	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
568709000087	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
568709000088	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
568709000089	active site
568709000090	metal binding site [ion binding]; metal-binding site
568709000091	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
568709000092	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
568709000093	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
568709000094	Sulfatase; Region: Sulfatase; pfam00884
568709000095	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
568709000096	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709000097	FeS/SAM binding site; other site
568709000098	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
568709000099	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
568709000100	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
568709000101	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
568709000102	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
568709000103	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709000104	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
568709000105	putative dimerization interface [polypeptide binding]; other site
568709000106	putative alpha-glucosidase; Provisional; Region: PRK10658
568709000107	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
568709000108	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
568709000109	putative active site [active]
568709000110	putative catalytic site [active]
568709000111	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
568709000112	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
568709000113	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
568709000114	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
568709000115	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
568709000116	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
568709000117	active site
568709000118	Riboflavin kinase; Region: Flavokinase; smart00904
568709000119	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
568709000120	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
568709000121	active site
568709000122	HIGH motif; other site
568709000123	nucleotide binding site [chemical binding]; other site
568709000124	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
568709000125	active site
568709000126	KMSKS motif; other site
568709000127	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
568709000128	tRNA binding surface [nucleotide binding]; other site
568709000129	anticodon binding site; other site
568709000130	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
568709000131	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
568709000132	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
568709000133	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
568709000134	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
568709000135	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
568709000136	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
568709000137	active site
568709000138	tetramer interface [polypeptide binding]; other site
568709000139	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
568709000140	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709000141	active site
568709000142	phosphorylation site [posttranslational modification]
568709000143	intermolecular recognition site; other site
568709000144	dimerization interface [polypeptide binding]; other site
568709000145	Transcriptional regulator; Region: CitT; pfam12431
568709000146	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
568709000147	PAS domain; Region: PAS; smart00091
568709000148	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709000149	ATP binding site [chemical binding]; other site
568709000150	Mg2+ binding site [ion binding]; other site
568709000151	G-X-G motif; other site
568709000153	oxaloacetate decarboxylase; Provisional; Region: PRK14040
568709000154	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
568709000155	active site
568709000156	catalytic residues [active]
568709000157	metal binding site [ion binding]; metal-binding site
568709000158	homodimer binding site [polypeptide binding]; other site
568709000159	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
568709000160	carboxyltransferase (CT) interaction site; other site
568709000161	biotinylation site [posttranslational modification]; other site
568709000162	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
568709000163	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
568709000164	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
568709000165	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
568709000166	putative active site [active]
568709000167	(T/H)XGH motif; other site
568709000168	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
568709000169	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
568709000170	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
568709000171	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
568709000172	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
568709000173	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
568709000174	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
568709000175	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
568709000176	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
568709000178	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
568709000179	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
568709000180	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
568709000181	catalytic site [active]
568709000182	subunit interface [polypeptide binding]; other site
568709000183	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
568709000184	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
568709000185	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
568709000186	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
568709000187	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
568709000188	ATP-grasp domain; Region: ATP-grasp_4; cl17255
568709000189	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
568709000190	IMP binding site; other site
568709000191	dimer interface [polypeptide binding]; other site
568709000192	interdomain contacts; other site
568709000193	partial ornithine binding site; other site
568709000194	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
568709000195	carnitine operon protein CaiE; Provisional; Region: PRK13627
568709000196	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
568709000197	putative trimer interface [polypeptide binding]; other site
568709000198	putative metal binding site [ion binding]; other site
568709000199	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
568709000200	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
568709000201	substrate binding site [chemical binding]; other site
568709000202	oxyanion hole (OAH) forming residues; other site
568709000203	trimer interface [polypeptide binding]; other site
568709000204	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
568709000205	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
568709000206	acyl-activating enzyme (AAE) consensus motif; other site
568709000207	putative AMP binding site [chemical binding]; other site
568709000208	putative active site [active]
568709000209	putative CoA binding site [chemical binding]; other site
568709000210	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
568709000211	CoA-transferase family III; Region: CoA_transf_3; pfam02515
568709000212	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
568709000213	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
568709000214	active site
568709000215	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
568709000216	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
568709000217	Ligand binding site [chemical binding]; other site
568709000218	Electron transfer flavoprotein domain; Region: ETF; pfam01012
568709000219	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
568709000220	Electron transfer flavoprotein domain; Region: ETF; smart00893
568709000221	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
568709000222	putative oxidoreductase FixC; Provisional; Region: PRK10157
568709000223	ferredoxin-like protein FixX; Provisional; Region: PRK15449
568709000224	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709000225	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
568709000226	putative substrate translocation pore; other site
568709000227	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
568709000228	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
568709000229	lacks the C-terminal region
568709000230	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
568709000231	Sulfatase; Region: Sulfatase; cl17466
568709000232	Sulfatase; Region: Sulfatase; cl17466
568709000233	Sulfatase; Region: Sulfatase; cl17466
568709000234	lacks the N-terminal region
568709000235	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
568709000236	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
568709000237	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
568709000238	TrkA-N domain; Region: TrkA_N; pfam02254
568709000239	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
568709000240	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
568709000241	folate binding site [chemical binding]; other site
568709000242	NADP+ binding site [chemical binding]; other site
568709000243	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
568709000244	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
568709000245	active site
568709000246	metal binding site [ion binding]; metal-binding site
568709000247	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
568709000248	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
568709000249	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
568709000250	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
568709000251	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
568709000252	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
568709000253	SurA N-terminal domain; Region: SurA_N; pfam09312
568709000254	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
568709000255	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
568709000256	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
568709000257	OstA-like protein; Region: OstA; pfam03968
568709000258	Organic solvent tolerance protein; Region: OstA_C; pfam04453
568709000259	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
568709000260	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
568709000261	putative metal binding site [ion binding]; other site
568709000262	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
568709000263	HSP70 interaction site [polypeptide binding]; other site
568709000264	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
568709000265	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
568709000266	active site
568709000267	ATP-dependent helicase HepA; Validated; Region: PRK04914
568709000268	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568709000269	ATP binding site [chemical binding]; other site
568709000270	putative Mg++ binding site [ion binding]; other site
568709000271	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709000272	nucleotide binding region [chemical binding]; other site
568709000273	ATP-binding site [chemical binding]; other site
568709000274	DNA polymerase II; Reviewed; Region: PRK05762
568709000275	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
568709000276	active site
568709000277	catalytic site [active]
568709000278	substrate binding site [chemical binding]; other site
568709000279	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
568709000280	active site
568709000281	metal-binding site
568709000282	Uncharacterized conserved protein [Function unknown]; Region: COG1434
568709000283	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
568709000284	putative active site [active]
568709000285	lacks C-terminal region
568709000286	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
568709000287	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
568709000288	intersubunit interface [polypeptide binding]; other site
568709000289	active site
568709000290	Zn2+ binding site [ion binding]; other site
568709000291	L-arabinose isomerase; Provisional; Region: PRK02929
568709000292	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
568709000293	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
568709000294	trimer interface [polypeptide binding]; other site
568709000295	putative substrate binding site [chemical binding]; other site
568709000296	putative metal binding site [ion binding]; other site
568709000297	ribulokinase; Provisional; Region: PRK04123
568709000298	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
568709000299	N- and C-terminal domain interface [polypeptide binding]; other site
568709000300	active site
568709000301	MgATP binding site [chemical binding]; other site
568709000302	catalytic site [active]
568709000303	metal binding site [ion binding]; metal-binding site
568709000304	carbohydrate binding site [chemical binding]; other site
568709000305	homodimer interface [polypeptide binding]; other site
568709000306	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
568709000307	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
568709000308	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709000309	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709000310	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
568709000311	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
568709000312	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
568709000313	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
568709000314	Walker A/P-loop; other site
568709000315	ATP binding site [chemical binding]; other site
568709000316	Q-loop/lid; other site
568709000317	ABC transporter signature motif; other site
568709000318	Walker B; other site
568709000319	D-loop; other site
568709000320	H-loop/switch region; other site
568709000321	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
568709000322	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709000323	dimer interface [polypeptide binding]; other site
568709000324	conserved gate region; other site
568709000325	putative PBP binding loops; other site
568709000326	ABC-ATPase subunit interface; other site
568709000327	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709000328	dimer interface [polypeptide binding]; other site
568709000329	conserved gate region; other site
568709000330	putative PBP binding loops; other site
568709000331	ABC-ATPase subunit interface; other site
568709000332	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
568709000333	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
568709000334	transcriptional regulator SgrR; Provisional; Region: PRK13626
568709000335	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
568709000336	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
568709000337	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
568709000338	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
568709000339	substrate binding site [chemical binding]; other site
568709000340	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
568709000341	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
568709000342	substrate binding site [chemical binding]; other site
568709000343	ligand binding site [chemical binding]; other site
568709000344	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
568709000345	tartrate dehydrogenase; Region: TTC; TIGR02089
568709000346	2-isopropylmalate synthase; Validated; Region: PRK00915
568709000347	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
568709000348	active site
568709000349	catalytic residues [active]
568709000350	metal binding site [ion binding]; metal-binding site
568709000351	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
568709000352	leu operon leader peptide; Provisional; Region: PRK14744
568709000353	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
568709000354	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709000355	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
568709000356	putative substrate binding pocket [chemical binding]; other site
568709000357	putative dimerization interface [polypeptide binding]; other site
568709000358	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
568709000359	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
568709000360	dimer interface [polypeptide binding]; other site
568709000361	PYR/PP interface [polypeptide binding]; other site
568709000362	TPP binding site [chemical binding]; other site
568709000363	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568709000364	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
568709000365	TPP-binding site [chemical binding]; other site
568709000366	dimer interface [polypeptide binding]; other site
568709000367	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
568709000368	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
568709000369	putative valine binding site [chemical binding]; other site
568709000370	dimer interface [polypeptide binding]; other site
568709000371	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
568709000372	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
568709000373	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709000374	DNA binding site [nucleotide binding]
568709000375	domain linker motif; other site
568709000376	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
568709000377	dimerization interface [polypeptide binding]; other site
568709000378	ligand binding site [chemical binding]; other site
568709000379	mraZ protein; Region: TIGR00242
568709000380	MraZ protein; Region: MraZ; pfam02381
568709000381	MraZ protein; Region: MraZ; pfam02381
568709000382	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
568709000383	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
568709000384	cell division protein FtsL; Provisional; Region: PRK10772
568709000385	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
568709000386	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
568709000387	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
568709000388	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
568709000389	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
568709000390	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568709000391	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568709000392	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
568709000393	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
568709000394	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568709000395	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568709000396	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
568709000397	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
568709000398	Mg++ binding site [ion binding]; other site
568709000399	putative catalytic motif [active]
568709000400	putative substrate binding site [chemical binding]; other site
568709000401	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
568709000402	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568709000403	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568709000404	cell division protein FtsW; Provisional; Region: PRK10774
568709000405	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
568709000406	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
568709000407	active site
568709000408	homodimer interface [polypeptide binding]; other site
568709000409	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
568709000410	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
568709000411	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568709000412	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568709000413	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
568709000414	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
568709000415	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
568709000416	cell division protein FtsQ; Provisional; Region: PRK10775
568709000417	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
568709000418	Cell division protein FtsQ; Region: FtsQ; pfam03799
568709000419	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
568709000420	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568709000421	Cell division protein FtsA; Region: FtsA; pfam14450
568709000422	cell division protein FtsZ; Validated; Region: PRK09330
568709000423	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
568709000424	nucleotide binding site [chemical binding]; other site
568709000425	SulA interaction site; other site
568709000426	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
568709000427	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
568709000428	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
568709000429	SecA regulator SecM; Provisional; Region: PRK02943
568709000430	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
568709000431	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
568709000432	SEC-C motif; Region: SEC-C; pfam02810
568709000433	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
568709000434	active site
568709000435	8-oxo-dGMP binding site [chemical binding]; other site
568709000436	nudix motif; other site
568709000437	metal binding site [ion binding]; metal-binding site
568709000438	DNA gyrase inhibitor; Reviewed; Region: PRK00418
568709000439	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
568709000440	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
568709000441	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
568709000442	CoA-binding site [chemical binding]; other site
568709000443	ATP-binding [chemical binding]; other site
568709000444	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
568709000445	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
568709000446	active site
568709000447	type IV pilin biogenesis protein; Provisional; Region: PRK10573
568709000448	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
568709000449	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
568709000450	hypothetical protein; Provisional; Region: PRK10436
568709000451	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
568709000452	Walker A motif; other site
568709000453	ATP binding site [chemical binding]; other site
568709000454	Walker B motif; other site
568709000455	putative major pilin subunit; Provisional; Region: PRK10574
568709000456	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
568709000457	Pilin (bacterial filament); Region: Pilin; pfam00114
568709000458	nicotinate-nucleotide pyrophosphorylase; Region: nadC; TIGR00078
568709000459	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
568709000460	dimerization interface [polypeptide binding]; other site
568709000461	active site
568709000462	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
568709000463	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
568709000464	amidase catalytic site [active]
568709000465	Zn binding residues [ion binding]; other site
568709000466	substrate binding site [chemical binding]; other site
568709000467	regulatory protein AmpE; Provisional; Region: PRK10987
568709000468	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
568709000469	active site
568709000470	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
568709000471	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709000472	putative substrate translocation pore; other site
568709000473	aromatic amino acid transporter; Provisional; Region: PRK10238
568709000474	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
568709000475	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709000476	DNA-binding site [nucleotide binding]; DNA binding site
568709000477	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
568709000478	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
568709000479	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
568709000480	dimer interface [polypeptide binding]; other site
568709000481	TPP-binding site [chemical binding]; other site
568709000482	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
568709000483	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
568709000484	E3 interaction surface; other site
568709000485	lipoyl attachment site [posttranslational modification]; other site
568709000486	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
568709000487	E3 interaction surface; other site
568709000488	lipoyl attachment site [posttranslational modification]; other site
568709000489	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
568709000490	E3 interaction surface; other site
568709000491	lipoyl attachment site [posttranslational modification]; other site
568709000492	e3 binding domain; Region: E3_binding; pfam02817
568709000493	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
568709000494	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
568709000495	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
568709000496	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709000497	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
568709000498	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
568709000499	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
568709000500	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
568709000501	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
568709000502	substrate binding site [chemical binding]; other site
568709000503	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
568709000504	substrate binding site [chemical binding]; other site
568709000505	ligand binding site [chemical binding]; other site
568709000506	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183
568709000507	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
568709000508	hypothetical protein; Provisional; Region: PRK05248
568709000509	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
568709000510	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
568709000511	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
568709000512	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
568709000513	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568709000514	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
568709000515	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709000516	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
568709000517	spermidine synthase; Provisional; Region: PRK00811
568709000518	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709000519	S-adenosylmethionine binding site [chemical binding]; other site
568709000520	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
568709000521	multicopper oxidase; Provisional; Region: PRK10965
568709000522	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
568709000523	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
568709000524	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
568709000525	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
568709000526	Trp docking motif [polypeptide binding]; other site
568709000527	putative active site [active]
568709000528	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
568709000529	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568709000530	active site
568709000531	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
568709000532	active site clefts [active]
568709000533	zinc binding site [ion binding]; other site
568709000534	dimer interface [polypeptide binding]; other site
568709000536	inner membrane transport permease; Provisional; Region: PRK15066
568709000537	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
568709000538	putative fimbrial protein StiH; Provisional; Region: PRK15297
568709000539	fimbrial outer membrane usher protein StiC; Provisional; Region: PRK15298
568709000540	PapC N-terminal domain; Region: PapC_N; pfam13954
568709000541	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709000542	PapC C-terminal domain; Region: PapC_C; pfam13953
568709000543	fimbrial chaperone protein StiB; Provisional; Region: PRK15299
568709000544	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709000545	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709000546	fimbrial protein StiA; Provisional; Region: PRK15300
568709000547	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
568709000548	active pocket/dimerization site; other site
568709000549	active site
568709000550	phosphorylation site [posttranslational modification]
568709000551	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
568709000552	putative active site [active]
568709000553	putative metal binding site [ion binding]; other site
568709000554	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
568709000555	tetramerization interface [polypeptide binding]; other site
568709000556	active site
568709000557	Pantoate-beta-alanine ligase; Region: PanC; cd00560
568709000558	pantoate--beta-alanine ligase; Region: panC; TIGR00018
568709000559	active site
568709000560	ATP-binding site [chemical binding]; other site
568709000561	pantoate-binding site; other site
568709000562	HXXH motif; other site
568709000563	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
568709000564	oligomerization interface [polypeptide binding]; other site
568709000565	active site
568709000566	metal binding site [ion binding]; metal-binding site
568709000567	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
568709000568	catalytic center binding site [active]
568709000569	ATP binding site [chemical binding]; other site
568709000570	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
568709000571	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
568709000572	active site
568709000573	NTP binding site [chemical binding]; other site
568709000574	metal binding triad [ion binding]; metal-binding site
568709000575	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
568709000576	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
568709000577	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
568709000578	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
568709000579	active site
568709000580	nucleotide binding site [chemical binding]; other site
568709000581	HIGH motif; other site
568709000582	KMSKS motif; other site
568709000583	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
568709000584	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
568709000585	2'-5' RNA ligase; Provisional; Region: PRK15124
568709000586	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
568709000587	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
568709000588	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
568709000589	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568709000590	ATP binding site [chemical binding]; other site
568709000591	putative Mg++ binding site [ion binding]; other site
568709000592	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709000593	nucleotide binding region [chemical binding]; other site
568709000594	ATP-binding site [chemical binding]; other site
568709000595	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
568709000596	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
568709000597	Transglycosylase; Region: Transgly; pfam00912
568709000598	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
568709000599	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
568709000600	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
568709000601	N-terminal plug; other site
568709000602	ligand-binding site [chemical binding]; other site
568709000603	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
568709000604	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
568709000605	Walker A/P-loop; other site
568709000606	ATP binding site [chemical binding]; other site
568709000607	Q-loop/lid; other site
568709000608	ABC transporter signature motif; other site
568709000609	Walker B; other site
568709000610	D-loop; other site
568709000611	H-loop/switch region; other site
568709000612	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
568709000613	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
568709000614	siderophore binding site; other site
568709000615	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
568709000616	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
568709000617	ABC-ATPase subunit  interface; other site
568709000618	dimer interface [polypeptide binding]; other site
568709000619	putative PBP binding regions; other site
568709000620	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
568709000621	ABC-ATPase subunit  interface; other site
568709000622	dimer interface [polypeptide binding]; other site
568709000623	putative PBP binding regions; other site
568709000624	putative fimbrial subunit StfA; Provisional; Region: PRK15283
568709000625	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
568709000626	PapC N-terminal domain; Region: PapC_N; pfam13954
568709000627	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709000628	PapC C-terminal domain; Region: PapC_C; pfam13953
568709000629	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
568709000630	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709000631	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709000632	putative minor fimbrial subunit StfE; Provisional; Region: PRK15286
568709000633	putative minor fimbrial subunit StfF; Provisional; Region: PRK15287
568709000634	putative minor fimbrial subunit StfG; Provisional; Region: PRK15288
568709000635	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
568709000636	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
568709000637	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
568709000638	inhibitor-cofactor binding pocket; inhibition site
568709000639	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709000640	catalytic residue [active]
568709000641	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
568709000642	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
568709000643	Cl- selectivity filter; other site
568709000644	Cl- binding residues [ion binding]; other site
568709000645	pore gating glutamate residue; other site
568709000646	dimer interface [polypeptide binding]; other site
568709000647	H+/Cl- coupling transport residue; other site
568709000648	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
568709000649	hypothetical protein; Provisional; Region: PRK10578
568709000650	UPF0126 domain; Region: UPF0126; pfam03458
568709000651	UPF0126 domain; Region: UPF0126; pfam03458
568709000652	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
568709000653	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
568709000654	cobalamin binding residues [chemical binding]; other site
568709000655	putative BtuC binding residues; other site
568709000656	dimer interface [polypeptide binding]; other site
568709000657	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
568709000658	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
568709000659	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
568709000660	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568709000661	Zn2+ binding site [ion binding]; other site
568709000662	Mg2+ binding site [ion binding]; other site
568709000663	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
568709000664	serine endoprotease; Provisional; Region: PRK10942
568709000665	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
568709000666	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
568709000667	protein binding site [polypeptide binding]; other site
568709000668	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
568709000669	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
568709000670	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
568709000671	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
568709000672	hypothetical protein; Provisional; Region: PRK13677
568709000673	shikimate transporter; Provisional; Region: PRK09952
568709000674	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709000675	putative substrate translocation pore; other site
568709000676	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
568709000677	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
568709000678	trimer interface [polypeptide binding]; other site
568709000679	active site
568709000680	substrate binding site [chemical binding]; other site
568709000681	CoA binding site [chemical binding]; other site
568709000682	PII uridylyl-transferase; Provisional; Region: PRK05007
568709000683	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
568709000684	metal binding triad; other site
568709000685	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
568709000686	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568709000687	Zn2+ binding site [ion binding]; other site
568709000688	Mg2+ binding site [ion binding]; other site
568709000689	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
568709000690	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
568709000691	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
568709000692	active site
568709000693	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
568709000694	rRNA interaction site [nucleotide binding]; other site
568709000695	S8 interaction site; other site
568709000696	putative laminin-1 binding site; other site
568709000697	elongation factor Ts; Provisional; Region: tsf; PRK09377
568709000698	UBA/TS-N domain; Region: UBA; pfam00627
568709000699	Elongation factor TS; Region: EF_TS; pfam00889
568709000700	Elongation factor TS; Region: EF_TS; pfam00889
568709000701	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
568709000702	putative nucleotide binding site [chemical binding]; other site
568709000703	uridine monophosphate binding site [chemical binding]; other site
568709000704	homohexameric interface [polypeptide binding]; other site
568709000705	ribosome recycling factor; Reviewed; Region: frr; PRK00083
568709000706	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
568709000707	hinge region; other site
568709000708	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
568709000709	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
568709000710	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
568709000711	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
568709000712	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
568709000713	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
568709000714	catalytic residue [active]
568709000715	putative FPP diphosphate  binding site; other site
568709000716	putative FPP binding hydrophobic cleft; other site
568709000717	dimer interface [polypeptide binding]; other site
568709000718	putative IPP diphosphate binding site; other site
568709000719	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
568709000720	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
568709000721	zinc metallopeptidase RseP; Provisional; Region: PRK10779
568709000722	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
568709000723	active site
568709000724	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
568709000725	protein binding site [polypeptide binding]; other site
568709000726	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
568709000727	protein binding site [polypeptide binding]; other site
568709000728	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
568709000729	putative substrate binding region [chemical binding]; other site
568709000730	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
568709000731	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
568709000732	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
568709000733	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
568709000734	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
568709000735	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
568709000736	Surface antigen; Region: Bac_surface_Ag; pfam01103
568709000737	periplasmic chaperone; Provisional; Region: PRK10780
568709000738	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
568709000739	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
568709000740	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
568709000741	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
568709000742	trimer interface [polypeptide binding]; other site
568709000743	active site
568709000744	UDP-GlcNAc binding site [chemical binding]; other site
568709000745	lipid binding site [chemical binding]; lipid-binding site
568709000746	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
568709000747	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
568709000748	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
568709000749	active site
568709000750	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
568709000751	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
568709000752	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
568709000753	RNA/DNA hybrid binding site [nucleotide binding]; other site
568709000754	active site
568709000755	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
568709000756	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
568709000757	putative active site [active]
568709000758	putative PHP Thumb interface [polypeptide binding]; other site
568709000759	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
568709000760	generic binding surface II; other site
568709000761	generic binding surface I; other site
568709000762	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
568709000763	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
568709000764	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
568709000765	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
568709000766	putative sugar binding site [chemical binding]; other site
568709000767	catalytic residues [active]
568709000768	PKD domain; Region: PKD; pfam00801
568709000769	lysine decarboxylase LdcC; Provisional; Region: PRK15399
568709000770	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
568709000771	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
568709000772	homodimer interface [polypeptide binding]; other site
568709000773	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709000774	catalytic residue [active]
568709000775	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
568709000776	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
568709000777	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
568709000778	putative metal binding site [ion binding]; other site
568709000779	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
568709000780	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
568709000781	TilS substrate binding domain; Region: TilS; pfam09179
568709000782	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
568709000783	Rho-binding antiterminator; Provisional; Region: PRK11625
568709000784	hypothetical protein; Provisional; Region: PRK04964
568709000785	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
568709000786	hypothetical protein; Provisional; Region: PRK09256
568709000787	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
568709000788	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
568709000789	NlpE N-terminal domain; Region: NlpE; pfam04170
568709000790	prolyl-tRNA synthetase; Provisional; Region: PRK09194
568709000791	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
568709000792	dimer interface [polypeptide binding]; other site
568709000793	motif 1; other site
568709000794	active site
568709000795	motif 2; other site
568709000796	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
568709000797	putative deacylase active site [active]
568709000798	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
568709000799	active site
568709000800	motif 3; other site
568709000801	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
568709000802	anticodon binding site; other site
568709000803	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
568709000804	homodimer interaction site [polypeptide binding]; other site
568709000805	cofactor binding site; other site
568709000806	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
568709000807	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
568709000808	lipoprotein, YaeC family; Region: TIGR00363
568709000809	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709000810	dimer interface [polypeptide binding]; other site
568709000811	conserved gate region; other site
568709000812	ABC-ATPase subunit interface; other site
568709000813	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
568709000814	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
568709000815	Walker A/P-loop; other site
568709000816	ATP binding site [chemical binding]; other site
568709000817	Q-loop/lid; other site
568709000818	ABC transporter signature motif; other site
568709000819	Walker B; other site
568709000820	D-loop; other site
568709000821	H-loop/switch region; other site
568709000822	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
568709000823	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
568709000824	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709000825	active site
568709000826	motif I; other site
568709000827	motif II; other site
568709000828	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568709000829	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568709000830	active site
568709000831	catalytic tetrad [active]
568709000832	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709000833	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709000834	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
568709000835	putative effector binding pocket; other site
568709000836	dimerization interface [polypeptide binding]; other site
568709000837	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
568709000838	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709000839	putative substrate translocation pore; other site
568709000840	hypothetical protein; Provisional; Region: PRK05421
568709000841	putative catalytic site [active]
568709000842	putative metal binding site [ion binding]; other site
568709000843	putative phosphate binding site [ion binding]; other site
568709000844	putative catalytic site [active]
568709000845	putative phosphate binding site [ion binding]; other site
568709000846	putative metal binding site [ion binding]; other site
568709000847	Methyltransferase domain; Region: Methyltransf_23; pfam13489
568709000848	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709000849	S-adenosylmethionine binding site [chemical binding]; other site
568709000850	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
568709000851	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
568709000852	N-acetyl-D-glucosamine binding site [chemical binding]; other site
568709000853	catalytic residue [active]
568709000854	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568709000855	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568709000856	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
568709000857	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709000858	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
568709000859	RNA/DNA hybrid binding site [nucleotide binding]; other site
568709000860	active site
568709000861	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
568709000862	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
568709000863	active site
568709000864	catalytic site [active]
568709000865	substrate binding site [chemical binding]; other site
568709000866	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
568709000867	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
568709000868	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
568709000869	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
568709000870	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
568709000871	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
568709000872	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
568709000873	ImpE protein; Region: ImpE; pfam07024
568709000874	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
568709000875	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709000876	Walker A motif; other site
568709000877	ATP binding site [chemical binding]; other site
568709000878	Walker B motif; other site
568709000879	arginine finger; other site
568709000880	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709000881	Walker A motif; other site
568709000882	ATP binding site [chemical binding]; other site
568709000883	Walker B motif; other site
568709000884	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
568709000885	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
568709000886	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
568709000887	Protein of unknown function (DUF877); Region: DUF877; pfam05943
568709000888	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
568709000889	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
568709000890	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
568709000891	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
568709000892	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
568709000893	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
568709000894	hypothetical protein; Provisional; Region: PRK08126
568709000895	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
568709000896	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
568709000897	ligand binding site [chemical binding]; other site
568709000898	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
568709000899	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
568709000900	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
568709000901	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; cl01611
568709000902	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4893
568709000903	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501
568709000904	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
568709000905	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
568709000906	Uncharacterized conserved protein [Function unknown]; Region: COG5435
568709000907	PAAR motif; Region: PAAR_motif; pfam05488
568709000908	RHS Repeat; Region: RHS_repeat; pfam05593
568709000909	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
568709000910	RHS Repeat; Region: RHS_repeat; pfam05593
568709000911	RHS Repeat; Region: RHS_repeat; pfam05593
568709000912	RHS protein; Region: RHS; pfam03527
568709000913	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
568709000914	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
568709000915	RHS protein; Region: RHS; pfam03527
568709000916	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
568709000917	carries stop codon in N-terminal region
568709000918	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
568709000919	has a frameshift after residue 81
568709000920	Transposase; Region: HTH_Tnp_1; cl17663
568709000921	lacks the N-terminal region and has three frameshifts after residues 43, 142 and 148
568709000922	Saf-pilin pilus formation protein SafA; Provisional; Region: PRK15221
568709000923	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
568709000924	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709000925	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709000926	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
568709000927	PapC N-terminal domain; Region: PapC_N; pfam13954
568709000928	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709000929	PapC C-terminal domain; Region: PapC_C; pfam13953
568709000930	putative pilin structural protein SafD; Provisional; Region: PRK15222
568709000931	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
568709000932	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
568709000933	putative active site [active]
568709000934	putative metal binding site [ion binding]; other site
568709000935	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709000936	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709000937	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709000938	dimerization interface [polypeptide binding]; other site
568709000939	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
568709000940	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
568709000941	dimer interface [polypeptide binding]; other site
568709000942	C-N hydrolase family amidase; Provisional; Region: PRK10438
568709000943	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
568709000944	putative active site [active]
568709000945	catalytic triad [active]
568709000946	dimer interface [polypeptide binding]; other site
568709000947	multimer interface [polypeptide binding]; other site
568709000948	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
568709000949	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
568709000950	active site
568709000951	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
568709000952	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
568709000953	dimer interface [polypeptide binding]; other site
568709000954	active site
568709000955	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
568709000956	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
568709000957	putative active site [active]
568709000958	putative dimer interface [polypeptide binding]; other site
568709000959	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
568709000960	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
568709000961	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
568709000962	active site
568709000963	DNA polymerase IV; Validated; Region: PRK02406
568709000964	DNA binding site [nucleotide binding]
568709000965	hypothetical protein; Reviewed; Region: PRK09588
568709000966	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
568709000967	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
568709000968	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
568709000969	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
568709000970	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
568709000971	metal binding site [ion binding]; metal-binding site
568709000972	dimer interface [polypeptide binding]; other site
568709000973	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568709000974	active site
568709000975	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
568709000976	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
568709000977	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
568709000978	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
568709000979	trimer interface [polypeptide binding]; other site
568709000980	eyelet of channel; other site
568709000981	gamma-glutamyl kinase; Provisional; Region: PRK05429
568709000982	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
568709000983	nucleotide binding site [chemical binding]; other site
568709000984	homotetrameric interface [polypeptide binding]; other site
568709000985	putative phosphate binding site [ion binding]; other site
568709000986	putative allosteric binding site; other site
568709000987	PUA domain; Region: PUA; pfam01472
568709000988	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
568709000989	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
568709000990	putative catalytic cysteine [active]
568709000991	HTH-like domain; Region: HTH_21; pfam13276
568709000992	Integrase core domain; Region: rve; pfam00665
568709000993	Integrase core domain; Region: rve_2; pfam13333
568709000994	lacks the N-terminal region and has a frameshift after residue 92
568709000995	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
568709000996	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
568709000997	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709000998	putative substrate translocation pore; other site
568709000999	isopropylmalate isomerase large subunit; Provisional; Region: PRK12466
568709001000	substrate binding site [chemical binding]; other site
568709001001	3-isopropylmalate dehydratase small subunit [Amino acid transport and metabolism]; Region: LeuD; COG0066
568709001002	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
568709001003	hypothetical protein; Provisional; Region: PRK14812
568709001004	substrate binding site [chemical binding]; other site
568709001005	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
568709001006	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
568709001007	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
568709001008	transcriptional activator TtdR; Provisional; Region: PRK09801
568709001009	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709001010	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
568709001011	putative effector binding pocket; other site
568709001012	putative dimerization interface [polypeptide binding]; other site
568709001013	YjzC-like protein; Region: YjzC; pfam14168
568709001014	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
568709001015	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709001016	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709001017	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
568709001018	fimbrial outer membrane usher protein StbC; Provisional; Region: PRK15248
568709001019	PapC N-terminal domain; Region: PapC_N; pfam13954
568709001020	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709001021	PapC C-terminal domain; Region: PapC_C; pfam13953
568709001022	fimbrial chaperone protein StbB; Provisional; Region: PRK15249
568709001023	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709001024	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709001025	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
568709001027	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
568709001028	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709001029	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
568709001030	DNA binding site [nucleotide binding]
568709001031	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
568709001032	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
568709001033	DNA binding residues [nucleotide binding]
568709001034	dimerization interface [polypeptide binding]; other site
568709001035	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
568709001036	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
568709001037	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
568709001038	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
568709001039	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
568709001040	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709001041	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
568709001042	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
568709001043	metal-binding site [ion binding]
568709001044	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568709001045	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709001046	motif II; other site
568709001047	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
568709001048	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
568709001049	DNA binding residues [nucleotide binding]
568709001050	dimer interface [polypeptide binding]; other site
568709001051	copper binding site [ion binding]; other site
568709001052	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
568709001053	metal-binding site [ion binding]
568709001054	putative sialic acid transporter; Region: 2A0112; TIGR00891
568709001055	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709001056	putative substrate translocation pore; other site
568709001057	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
568709001058	DNA methylase; Region: N6_N4_Mtase; cl17433
568709001059	DNA methylase; Region: N6_N4_Mtase; pfam01555
568709001060	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
568709001061	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
568709001062	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
568709001063	VRR-NUC domain; Region: VRR_NUC; pfam08774
568709001064	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
568709001065	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
568709001066	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
568709001067	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
568709001068	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568709001069	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
568709001070	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
568709001071	N-terminal plug; other site
568709001072	ligand-binding site [chemical binding]; other site
568709001073	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
568709001074	hypothetical protein; Provisional; Region: PRK09929
568709001075	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
568709001076	Propionate catabolism activator; Region: PrpR_N; pfam06506
568709001077	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709001078	Walker A motif; other site
568709001079	ATP binding site [chemical binding]; other site
568709001080	Walker B motif; other site
568709001081	arginine finger; other site
568709001082	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
568709001083	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
568709001084	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
568709001085	tetramer interface [polypeptide binding]; other site
568709001086	active site
568709001087	Mg2+/Mn2+ binding site [ion binding]; other site
568709001088	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
568709001089	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
568709001090	dimer interface [polypeptide binding]; other site
568709001091	active site
568709001092	citrylCoA binding site [chemical binding]; other site
568709001093	oxalacetate/citrate binding site [chemical binding]; other site
568709001094	coenzyme A binding site [chemical binding]; other site
568709001095	catalytic triad [active]
568709001096	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
568709001097	2-methylcitrate dehydratase; Region: prpD; TIGR02330
568709001098	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
568709001099	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
568709001100	acyl-activating enzyme (AAE) consensus motif; other site
568709001101	AMP binding site [chemical binding]; other site
568709001102	active site
568709001103	CoA binding site [chemical binding]; other site
568709001104	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
568709001105	dimer interface [polypeptide binding]; other site
568709001106	active site
568709001107	Schiff base residues; other site
568709001108	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
568709001109	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
568709001110	Autotransporter beta-domain; Region: Autotransporter; pfam03797
568709001111	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
568709001112	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
568709001113	ligand binding site [chemical binding]; other site
568709001114	flexible hinge region; other site
568709001115	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
568709001116	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
568709001117	microcin B17 transporter; Reviewed; Region: PRK11098
568709001118	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
568709001119	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
568709001120	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
568709001121	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
568709001122	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
568709001123	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
568709001124	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
568709001125	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
568709001126	drug efflux system protein MdtG; Provisional; Region: PRK09874
568709001127	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709001128	putative substrate translocation pore; other site
568709001129	anti-RssB factor; Provisional; Region: PRK10244
568709001130	hypothetical protein; Provisional; Region: PRK11505
568709001131	psiF repeat; Region: PsiF_repeat; pfam07769
568709001132	psiF repeat; Region: PsiF_repeat; pfam07769
568709001133	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
568709001134	MASE2 domain; Region: MASE2; pfam05230
568709001135	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568709001136	metal binding site [ion binding]; metal-binding site
568709001137	active site
568709001138	I-site; other site
568709001139	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
568709001140	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
568709001141	hypothetical protein; Validated; Region: PRK00124
568709001142	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
568709001143	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
568709001144	ADP binding site [chemical binding]; other site
568709001145	magnesium binding site [ion binding]; other site
568709001146	putative shikimate binding site; other site
568709001147	hypothetical protein; Provisional; Region: PRK10380
568709001148	hypothetical protein; Provisional; Region: PRK10481
568709001149	hypothetical protein; Provisional; Region: PRK10579
568709001150	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
568709001151	fructokinase; Reviewed; Region: PRK09557
568709001152	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568709001153	nucleotide binding site [chemical binding]; other site
568709001154	MFS transport protein AraJ; Provisional; Region: PRK10091
568709001155	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709001156	putative substrate translocation pore; other site
568709001157	exonuclease subunit SbcC; Provisional; Region: PRK10246
568709001158	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709001159	Walker A/P-loop; other site
568709001160	ATP binding site [chemical binding]; other site
568709001161	Q-loop/lid; other site
568709001162	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709001163	ABC transporter signature motif; other site
568709001164	Walker B; other site
568709001165	D-loop; other site
568709001166	H-loop/switch region; other site
568709001167	exonuclease subunit SbcD; Provisional; Region: PRK10966
568709001168	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
568709001169	active site
568709001170	metal binding site [ion binding]; metal-binding site
568709001171	DNA binding site [nucleotide binding]
568709001172	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
568709001173	transcriptional regulator PhoB; Provisional; Region: PRK10161
568709001174	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709001175	active site
568709001176	phosphorylation site [posttranslational modification]
568709001177	intermolecular recognition site; other site
568709001178	dimerization interface [polypeptide binding]; other site
568709001179	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709001180	DNA binding site [nucleotide binding]
568709001181	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
568709001182	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
568709001183	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
568709001184	putative active site [active]
568709001185	heme pocket [chemical binding]; other site
568709001186	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709001187	dimer interface [polypeptide binding]; other site
568709001188	phosphorylation site [posttranslational modification]
568709001189	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709001190	ATP binding site [chemical binding]; other site
568709001191	Mg2+ binding site [ion binding]; other site
568709001192	G-X-G motif; other site
568709001193	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
568709001194	putative proline-specific permease; Provisional; Region: proY; PRK10580
568709001195	maltodextrin glucosidase; Provisional; Region: PRK10785
568709001196	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
568709001197	homodimer interface [polypeptide binding]; other site
568709001198	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
568709001199	active site
568709001200	homodimer interface [polypeptide binding]; other site
568709001201	catalytic site [active]
568709001202	peroxidase; Provisional; Region: PRK15000
568709001203	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
568709001204	dimer interface [polypeptide binding]; other site
568709001205	decamer (pentamer of dimers) interface [polypeptide binding]; other site
568709001206	catalytic triad [active]
568709001207	peroxidatic and resolving cysteines [active]
568709001208	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
568709001209	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
568709001210	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
568709001211	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
568709001212	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
568709001213	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
568709001214	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
568709001215	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
568709001216	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
568709001217	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
568709001218	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
568709001219	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
568709001220	Protein export membrane protein; Region: SecD_SecF; pfam02355
568709001221	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
568709001222	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
568709001223	Predicted transcriptional regulator [Transcription]; Region: COG2378
568709001224	HTH domain; Region: HTH_11; pfam08279
568709001225	WYL domain; Region: WYL; pfam13280
568709001226	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
568709001227	active site
568709001228	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
568709001229	hypothetical protein; Provisional; Region: PRK11530
568709001230	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
568709001231	ATP cone domain; Region: ATP-cone; pfam03477
568709001232	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
568709001233	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
568709001234	catalytic motif [active]
568709001235	Zn binding site [ion binding]; other site
568709001236	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
568709001237	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
568709001238	homopentamer interface [polypeptide binding]; other site
568709001239	active site
568709001240	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
568709001241	putative RNA binding site [nucleotide binding]; other site
568709001242	thiamine monophosphate kinase; Provisional; Region: PRK05731
568709001243	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
568709001244	ATP binding site [chemical binding]; other site
568709001245	dimerization interface [polypeptide binding]; other site
568709001246	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
568709001247	tetramer interfaces [polypeptide binding]; other site
568709001248	binuclear metal-binding site [ion binding]; other site
568709001249	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568709001250	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568709001251	active site
568709001252	catalytic tetrad [active]
568709001253	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
568709001254	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
568709001255	TPP-binding site; other site
568709001256	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
568709001257	PYR/PP interface [polypeptide binding]; other site
568709001258	dimer interface [polypeptide binding]; other site
568709001259	TPP binding site [chemical binding]; other site
568709001260	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
568709001261	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
568709001262	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
568709001263	substrate binding pocket [chemical binding]; other site
568709001264	chain length determination region; other site
568709001265	substrate-Mg2+ binding site; other site
568709001266	catalytic residues [active]
568709001267	aspartate-rich region 1; other site
568709001268	active site lid residues [active]
568709001269	aspartate-rich region 2; other site
568709001270	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
568709001271	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
568709001272	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
568709001273	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
568709001274	Ligand Binding Site [chemical binding]; other site
568709001275	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
568709001276	active site residue [active]
568709001277	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
568709001278	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709001279	dimer interface [polypeptide binding]; other site
568709001280	conserved gate region; other site
568709001281	ABC-ATPase subunit interface; other site
568709001282	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
568709001283	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709001284	dimer interface [polypeptide binding]; other site
568709001285	conserved gate region; other site
568709001286	putative PBP binding loops; other site
568709001287	ABC-ATPase subunit interface; other site
568709001288	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
568709001289	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709001290	Walker A/P-loop; other site
568709001291	ATP binding site [chemical binding]; other site
568709001292	Q-loop/lid; other site
568709001293	ABC transporter signature motif; other site
568709001294	Walker B; other site
568709001295	D-loop; other site
568709001296	H-loop/switch region; other site
568709001297	TOBE domain; Region: TOBE_2; pfam08402
568709001298	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
568709001299	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
568709001300	transcriptional regulator protein; Region: phnR; TIGR03337
568709001301	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709001302	DNA-binding site [nucleotide binding]; DNA binding site
568709001303	UTRA domain; Region: UTRA; pfam07702
568709001304	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
568709001305	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568709001306	catalytic residue [active]
568709001307	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
568709001308	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709001309	motif II; other site
568709001310	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
568709001311	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
568709001312	conserved cys residue [active]
568709001313	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
568709001314	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
568709001315	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
568709001316	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
568709001317	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
568709001318	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709001319	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568709001320	putative substrate translocation pore; other site
568709001321	Sel1-like repeats; Region: SEL1; smart00671
568709001322	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
568709001323	Sel1 repeat; Region: Sel1; pfam08238
568709001324	Sel1-like repeats; Region: SEL1; smart00671
568709001325	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
568709001326	Sel1-like repeats; Region: SEL1; smart00671
568709001327	Sel1-like repeats; Region: SEL1; smart00671
568709001328	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
568709001329	UbiA prenyltransferase family; Region: UbiA; pfam01040
568709001330	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
568709001331	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
568709001332	Subunit III/IV interface [polypeptide binding]; other site
568709001333	Subunit I/III interface [polypeptide binding]; other site
568709001334	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
568709001335	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
568709001336	D-pathway; other site
568709001337	Putative ubiquinol binding site [chemical binding]; other site
568709001338	Low-spin heme (heme b) binding site [chemical binding]; other site
568709001339	Putative water exit pathway; other site
568709001340	Binuclear center (heme o3/CuB) [ion binding]; other site
568709001341	K-pathway; other site
568709001342	Putative proton exit pathway; other site
568709001343	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
568709001344	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
568709001345	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
568709001346	muropeptide transporter; Reviewed; Region: ampG; PRK11902
568709001347	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709001348	putative substrate translocation pore; other site
568709001349	hypothetical protein; Provisional; Region: PRK11627
568709001350	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
568709001351	transcriptional regulator BolA; Provisional; Region: PRK11628
568709001352	trigger factor; Provisional; Region: tig; PRK01490
568709001353	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
568709001354	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
568709001355	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
568709001356	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
568709001357	oligomer interface [polypeptide binding]; other site
568709001358	active site residues [active]
568709001359	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
568709001360	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
568709001361	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709001362	Walker A motif; other site
568709001363	ATP binding site [chemical binding]; other site
568709001364	Walker B motif; other site
568709001365	Iron permease FTR1 family; Region: FTR1; cl00475
568709001366	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
568709001367	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
568709001368	Found in ATP-dependent protease La (LON); Region: LON; smart00464
568709001369	Found in ATP-dependent protease La (LON); Region: LON; smart00464
568709001370	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709001371	Walker A motif; other site
568709001372	ATP binding site [chemical binding]; other site
568709001373	Walker B motif; other site
568709001374	arginine finger; other site
568709001375	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
568709001376	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
568709001377	IHF dimer interface [polypeptide binding]; other site
568709001378	IHF - DNA interface [nucleotide binding]; other site
568709001379	periplasmic folding chaperone; Provisional; Region: PRK10788
568709001380	SurA N-terminal domain; Region: SurA_N_3; cl07813
568709001381	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
568709001382	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
568709001383	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
568709001384	active site
568709001385	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
568709001386	Ligand Binding Site [chemical binding]; other site
568709001387	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
568709001388	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
568709001389	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
568709001392	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
568709001393	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568709001394	putative DNA binding site [nucleotide binding]; other site
568709001395	putative Zn2+ binding site [ion binding]; other site
568709001396	AsnC family; Region: AsnC_trans_reg; pfam01037
568709001397	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
568709001398	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568709001399	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709001400	Walker A/P-loop; other site
568709001401	ATP binding site [chemical binding]; other site
568709001402	Q-loop/lid; other site
568709001403	ABC transporter signature motif; other site
568709001404	Walker B; other site
568709001405	D-loop; other site
568709001406	H-loop/switch region; other site
568709001407	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
568709001408	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568709001409	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709001410	Walker A/P-loop; other site
568709001411	ATP binding site [chemical binding]; other site
568709001412	Q-loop/lid; other site
568709001413	ABC transporter signature motif; other site
568709001414	Walker B; other site
568709001415	D-loop; other site
568709001416	H-loop/switch region; other site
568709001417	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
568709001418	Nitrogen regulatory protein P-II; Region: P-II; smart00938
568709001419	ammonium transporter; Provisional; Region: PRK10666
568709001420	acyl-CoA thioesterase II; Provisional; Region: PRK10526
568709001421	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
568709001422	active site
568709001423	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
568709001424	catalytic triad [active]
568709001425	dimer interface [polypeptide binding]; other site
568709001426	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
568709001427	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
568709001428	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
568709001429	DNA binding site [nucleotide binding]
568709001430	active site
568709001431	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
568709001432	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
568709001433	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709001434	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
568709001435	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
568709001436	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
568709001437	maltose O-acetyltransferase; Provisional; Region: PRK10092
568709001438	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
568709001439	active site
568709001440	substrate binding site [chemical binding]; other site
568709001441	trimer interface [polypeptide binding]; other site
568709001442	CoA binding site [chemical binding]; other site
568709001443	gene expression modulator; Provisional; Region: PRK10945
568709001444	Hha toxicity attenuator; Provisional; Region: PRK10667
568709001445	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
568709001446	Protein export membrane protein; Region: SecD_SecF; cl14618
568709001447	Protein export membrane protein; Region: SecD_SecF; cl14618
568709001448	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
568709001449	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709001450	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
568709001451	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709001452	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
568709001453	hypothetical protein; Provisional; Region: PRK11281
568709001454	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
568709001455	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
568709001456	Mechanosensitive ion channel; Region: MS_channel; pfam00924
568709001457	Uncharacterized conserved protein [Function unknown]; Region: COG5464
568709001458	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
568709001459	hypothetical protein; Provisional; Region: PRK11038
568709001460	primosomal replication protein N''; Provisional; Region: PRK10093
568709001461	hypothetical protein; Provisional; Region: PRK10527
568709001462	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568709001463	active site
568709001464	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
568709001465	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709001466	Walker A motif; other site
568709001467	ATP binding site [chemical binding]; other site
568709001468	Walker B motif; other site
568709001469	DNA polymerase III subunit delta'; Validated; Region: PRK08485
568709001470	arginine finger; other site
568709001471	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
568709001472	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
568709001473	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
568709001474	hypothetical protein; Validated; Region: PRK00153
568709001475	recombination protein RecR; Reviewed; Region: recR; PRK00076
568709001476	RecR protein; Region: RecR; pfam02132
568709001477	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
568709001478	putative active site [active]
568709001479	putative metal-binding site [ion binding]; other site
568709001480	tetramer interface [polypeptide binding]; other site
568709001481	heat shock protein 90; Provisional; Region: PRK05218
568709001482	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709001483	ATP binding site [chemical binding]; other site
568709001484	Mg2+ binding site [ion binding]; other site
568709001485	G-X-G motif; other site
568709001486	adenylate kinase; Reviewed; Region: adk; PRK00279
568709001487	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
568709001488	AMP-binding site [chemical binding]; other site
568709001489	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
568709001490	ferrochelatase; Reviewed; Region: hemH; PRK00035
568709001491	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
568709001492	C-terminal domain interface [polypeptide binding]; other site
568709001493	active site
568709001494	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
568709001495	active site
568709001496	N-terminal domain interface [polypeptide binding]; other site
568709001497	acetyl esterase; Provisional; Region: PRK10162
568709001498	inosine/guanosine kinase; Provisional; Region: PRK15074
568709001499	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709001500	putative cation:proton antiport protein; Provisional; Region: PRK10669
568709001501	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
568709001502	TrkA-N domain; Region: TrkA_N; pfam02254
568709001503	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709001504	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568709001505	putative substrate translocation pore; other site
568709001506	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
568709001507	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
568709001508	active site
568709001509	metal binding site [ion binding]; metal-binding site
568709001510	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
568709001511	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
568709001512	putative deacylase active site [active]
568709001513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
568709001514	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
568709001515	copper exporting ATPase; Provisional; Region: copA; PRK10671
568709001516	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
568709001517	metal-binding site [ion binding]
568709001518	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
568709001519	metal-binding site [ion binding]
568709001520	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568709001521	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709001522	motif II; other site
568709001523	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
568709001524	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
568709001525	DNA binding residues [nucleotide binding]
568709001526	dimer interface [polypeptide binding]; other site
568709001527	copper binding site [ion binding]; other site
568709001528	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
568709001529	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
568709001530	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
568709001531	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
568709001532	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
568709001533	Walker A/P-loop; other site
568709001534	ATP binding site [chemical binding]; other site
568709001535	Q-loop/lid; other site
568709001536	ABC transporter signature motif; other site
568709001537	Walker B; other site
568709001538	D-loop; other site
568709001539	H-loop/switch region; other site
568709001540	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
568709001541	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
568709001542	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
568709001543	oxidoreductase; Provisional; Region: PRK08017
568709001544	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
568709001545	NADP binding site [chemical binding]; other site
568709001546	active site
568709001547	steroid binding site; other site
568709001548	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
568709001549	active site
568709001550	catalytic triad [active]
568709001551	oxyanion hole [active]
568709001552	switch loop; other site
568709001553	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
568709001554	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568709001555	Walker A/P-loop; other site
568709001556	ATP binding site [chemical binding]; other site
568709001557	Q-loop/lid; other site
568709001558	ABC transporter signature motif; other site
568709001559	Walker B; other site
568709001560	D-loop; other site
568709001561	H-loop/switch region; other site
568709001562	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
568709001563	FtsX-like permease family; Region: FtsX; pfam02687
568709001564	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
568709001565	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
568709001566	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
568709001567	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
568709001568	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
568709001569	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
568709001570	Walker A/P-loop; other site
568709001571	ATP binding site [chemical binding]; other site
568709001572	Q-loop/lid; other site
568709001573	ABC transporter signature motif; other site
568709001574	Walker B; other site
568709001575	D-loop; other site
568709001576	H-loop/switch region; other site
568709001577	NIL domain; Region: NIL; pfam09383
568709001578	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709001579	dimer interface [polypeptide binding]; other site
568709001580	conserved gate region; other site
568709001581	ABC-ATPase subunit interface; other site
568709001582	Predicted ATPase [General function prediction only]; Region: COG2603
568709001583	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
568709001584	active site residue [active]
568709001585	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
568709001586	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709001587	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709001588	dimerization interface [polypeptide binding]; other site
568709001589	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
568709001590	ureidoglycolate hydrolase; Provisional; Region: PRK03606
568709001591	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
568709001592	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
568709001593	Bacterial transcriptional regulator; Region: IclR; pfam01614
568709001594	glyoxylate carboligase; Provisional; Region: PRK11269
568709001595	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
568709001596	PYR/PP interface [polypeptide binding]; other site
568709001597	dimer interface [polypeptide binding]; other site
568709001598	TPP binding site [chemical binding]; other site
568709001599	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568709001600	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
568709001601	TPP-binding site [chemical binding]; other site
568709001602	hydroxypyruvate isomerase; Provisional; Region: PRK09997
568709001603	tartronate semialdehyde reductase; Provisional; Region: PRK15059
568709001604	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
568709001605	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709001606	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568709001607	putative substrate translocation pore; other site
568709001609	allantoinase; Provisional; Region: PRK08044
568709001610	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
568709001611	active site
568709001612	putative uracil/xanthine transporter; Provisional; Region: PRK11412
568709001613	glycerate kinase II; Provisional; Region: PRK09932
568709001614	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
568709001615	Mif2/CENP-C like; Region: Mif2; pfam11699
568709001616	Cupin domain; Region: Cupin_2; pfam07883
568709001617	allantoate amidohydrolase; Region: AllC; TIGR03176
568709001618	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
568709001619	active site
568709001620	metal binding site [ion binding]; metal-binding site
568709001621	dimer interface [polypeptide binding]; other site
568709001622	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
568709001623	membrane protein FdrA; Validated; Region: PRK06091
568709001624	CoA binding domain; Region: CoA_binding; pfam02629
568709001625	CoA-ligase; Region: Ligase_CoA; pfam00549
568709001626	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
568709001627	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
568709001628	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
568709001629	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
568709001630	putative substrate binding site [chemical binding]; other site
568709001631	nucleotide binding site [chemical binding]; other site
568709001632	nucleotide binding site [chemical binding]; other site
568709001633	homodimer interface [polypeptide binding]; other site
568709001634	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
568709001635	ATP-grasp domain; Region: ATP-grasp; pfam02222
568709001636	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
568709001637	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
568709001638	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
568709001639	putative active site [active]
568709001640	putative metal binding site [ion binding]; other site
568709001641	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
568709001642	substrate binding site [chemical binding]; other site
568709001643	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
568709001644	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
568709001645	active site
568709001646	HIGH motif; other site
568709001647	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
568709001648	KMSKS motif; other site
568709001649	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
568709001650	tRNA binding surface [nucleotide binding]; other site
568709001651	anticodon binding site; other site
568709001652	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4727
568709001653	Uncharacterized protein conserved in bacteria (DUF2145); Region: DUF2145; pfam09916
568709001654	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
568709001655	ribosome-associated protein; Provisional; Region: PRK11507
568709001656	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
568709001657	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
568709001658	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
568709001659	homodimer interface [polypeptide binding]; other site
568709001660	NADP binding site [chemical binding]; other site
568709001661	substrate binding site [chemical binding]; other site
568709001662	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
568709001663	fimbrial protein FimI; Provisional; Region: PRK15200
568709001664	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
568709001665	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709001666	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709001667	outer membrane usher protein FimD; Provisional; Region: PRK15198
568709001668	PapC N-terminal domain; Region: PapC_N; pfam13954
568709001669	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709001670	PapC C-terminal domain; Region: PapC_C; pfam13953
568709001671	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
568709001672	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
568709001673	transcriptional regulator FimZ; Provisional; Region: PRK09935
568709001674	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709001675	active site
568709001676	phosphorylation site [posttranslational modification]
568709001677	intermolecular recognition site; other site
568709001678	dimerization interface [polypeptide binding]; other site
568709001679	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709001680	DNA binding residues [nucleotide binding]
568709001681	dimerization interface [polypeptide binding]; other site
568709001682	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
568709001683	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709001684	DNA binding residues [nucleotide binding]
568709001685	dimerization interface [polypeptide binding]; other site
568709001687	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
568709001688	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
568709001689	Ligand binding site; other site
568709001690	Putative Catalytic site; other site
568709001691	DXD motif; other site
568709001692	Predicted membrane protein [Function unknown]; Region: COG2246
568709001693	GtrA-like protein; Region: GtrA; pfam04138
568709001694	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709001695	ATP binding site [chemical binding]; other site
568709001696	Mg2+ binding site [ion binding]; other site
568709001697	G-X-G motif; other site
568709001699	Cupin; Region: Cupin_6; pfam12852
568709001700	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
568709001701	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709001702	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709001703	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
568709001704	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709001705	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
568709001706	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
568709001707	Predicted membrane protein [Function unknown]; Region: COG3059
568709001708	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
568709001709	phenylalanine transporter; Provisional; Region: PRK10249
568709001710	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
568709001711	Mechanosensitive ion channel; Region: MS_channel; pfam00924
568709001712	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
568709001713	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
568709001714	active site
568709001715	oxyanion hole [active]
568709001716	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
568709001717	catalytic triad [active]
568709001718	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
568709001719	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
568709001720	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709001721	ATP binding site [chemical binding]; other site
568709001722	Walker B motif; other site
568709001723	arginine finger; other site
568709001724	Transcriptional antiterminator [Transcription]; Region: COG3933
568709001725	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
568709001726	active pocket/dimerization site; other site
568709001727	active site
568709001728	phosphorylation site [posttranslational modification]
568709001729	PRD domain; Region: PRD; pfam00874
568709001730	absent from CT18
568709001731	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
568709001732	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
568709001733	putative active site [active]
568709001734	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
568709001735	dimer interface [polypeptide binding]; other site
568709001736	active site
568709001737	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
568709001738	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
568709001739	dimer interface [polypeptide binding]; other site
568709001740	active site
568709001741	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
568709001742	dimer interface [polypeptide binding]; other site
568709001743	active site
568709001744	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
568709001745	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
568709001746	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
568709001747	active site
568709001748	phosphorylation site [posttranslational modification]
568709001749	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
568709001750	active pocket/dimerization site; other site
568709001751	active site
568709001752	phosphorylation site [posttranslational modification]
568709001753	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
568709001754	dimer interface [polypeptide binding]; other site
568709001755	FMN binding site [chemical binding]; other site
568709001756	hypothetical protein; Provisional; Region: PRK10250
568709001757	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568709001758	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709001759	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
568709001760	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709001761	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
568709001762	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
568709001763	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
568709001764	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
568709001765	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
568709001766	outer membrane receptor FepA; Provisional; Region: PRK13524
568709001767	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
568709001768	N-terminal plug; other site
568709001769	ligand-binding site [chemical binding]; other site
568709001770	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
568709001771	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
568709001772	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
568709001773	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
568709001774	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
568709001775	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
568709001776	acyl-activating enzyme (AAE) consensus motif; other site
568709001777	AMP binding site [chemical binding]; other site
568709001778	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
568709001780	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
568709001781	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
568709001782	Walker A/P-loop; other site
568709001783	ATP binding site [chemical binding]; other site
568709001784	Q-loop/lid; other site
568709001785	ABC transporter signature motif; other site
568709001786	Walker B; other site
568709001787	D-loop; other site
568709001788	H-loop/switch region; other site
568709001789	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
568709001790	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
568709001791	ABC-ATPase subunit  interface; other site
568709001792	dimer interface [polypeptide binding]; other site
568709001793	putative PBP binding regions; other site
568709001794	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
568709001795	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
568709001796	ABC-ATPase subunit  interface; other site
568709001797	dimer interface [polypeptide binding]; other site
568709001798	putative PBP binding regions; other site
568709001799	enterobactin exporter EntS; Provisional; Region: PRK10489
568709001800	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709001801	putative substrate translocation pore; other site
568709001802	ABC-type Fe2+-enterobactin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG4592
568709001803	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
568709001804	siderophore binding site; other site
568709001805	isochorismate synthase EntC; Provisional; Region: PRK15016
568709001806	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
568709001807	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
568709001808	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
568709001809	acyl-activating enzyme (AAE) consensus motif; other site
568709001810	active site
568709001811	AMP binding site [chemical binding]; other site
568709001812	substrate binding site [chemical binding]; other site
568709001813	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
568709001814	hydrophobic substrate binding pocket; other site
568709001815	Isochorismatase family; Region: Isochorismatase; pfam00857
568709001816	active site
568709001817	conserved cis-peptide bond; other site
568709001818	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
568709001819	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
568709001820	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
568709001821	putative NAD(P) binding site [chemical binding]; other site
568709001822	active site
568709001823	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
568709001824	CoenzymeA binding site [chemical binding]; other site
568709001825	subunit interaction site [polypeptide binding]; other site
568709001826	PHB binding site; other site
568709001827	carbon starvation protein A; Provisional; Region: PRK15015
568709001828	Carbon starvation protein CstA; Region: CstA; pfam02554
568709001829	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
568709001830	Uncharacterized small protein [Function unknown]; Region: COG2879
568709001831	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
568709001832	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
568709001833	putative active site [active]
568709001834	metal binding site [ion binding]; metal-binding site
568709001835	methionine aminotransferase; Validated; Region: PRK09082
568709001836	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709001837	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709001838	homodimer interface [polypeptide binding]; other site
568709001839	catalytic residue [active]
568709001840	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
568709001841	ParB-like nuclease domain; Region: ParBc; pfam02195
568709001842	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
568709001843	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
568709001844	Active Sites [active]
568709001845	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
568709001846	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
568709001847	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709001848	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709001849	dimerization interface [polypeptide binding]; other site
568709001850	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
568709001851	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
568709001852	dimerization domain [polypeptide binding]; other site
568709001853	dimer interface [polypeptide binding]; other site
568709001854	catalytic residues [active]
568709001855	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
568709001856	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
568709001857	dimer interface [polypeptide binding]; other site
568709001858	decamer (pentamer of dimers) interface [polypeptide binding]; other site
568709001859	catalytic triad [active]
568709001860	peroxidatic and resolving cysteines [active]
568709001861	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
568709001862	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
568709001863	catalytic residue [active]
568709001864	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
568709001865	catalytic residues [active]
568709001866	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568709001867	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709001868	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
568709001869	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
568709001870	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
568709001871	putative [4Fe-4S] binding site [ion binding]; other site
568709001872	putative molybdopterin cofactor binding site [chemical binding]; other site
568709001873	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
568709001874	molybdopterin cofactor binding site; other site
568709001875	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
568709001876	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
568709001877	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
568709001878	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
568709001879	Ligand Binding Site [chemical binding]; other site
568709001880	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
568709001881	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
568709001882	NAD binding site [chemical binding]; other site
568709001883	catalytic Zn binding site [ion binding]; other site
568709001884	structural Zn binding site [ion binding]; other site
568709001885	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
568709001886	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
568709001887	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
568709001888	B1 nucleotide binding pocket [chemical binding]; other site
568709001889	B2 nucleotide binding pocket [chemical binding]; other site
568709001890	CAS motifs; other site
568709001891	active site
568709001892	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
568709001893	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
568709001894	transmembrane helices; other site
568709001895	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
568709001896	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
568709001897	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
568709001898	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
568709001899	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
568709001900	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
568709001901	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
568709001902	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
568709001903	putative active site [active]
568709001904	(T/H)XGH motif; other site
568709001906	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
568709001907	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709001908	active site
568709001909	phosphorylation site [posttranslational modification]
568709001910	intermolecular recognition site; other site
568709001911	dimerization interface [polypeptide binding]; other site
568709001912	Transcriptional regulator; Region: CitT; pfam12431
568709001913	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
568709001914	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
568709001915	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
568709001916	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
568709001917	DNA-binding site [nucleotide binding]; DNA binding site
568709001918	RNA-binding motif; other site
568709001919	chromosome condensation membrane protein; Provisional; Region: PRK14196
568709001920	Predicted amidohydrolase [General function prediction only]; Region: COG0388
568709001921	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
568709001922	putative active site [active]
568709001923	catalytic triad [active]
568709001924	putative dimer interface [polypeptide binding]; other site
568709001925	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
568709001926	lipoyl synthase; Provisional; Region: PRK05481
568709001927	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709001928	FeS/SAM binding site; other site
568709001929	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
568709001930	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709001931	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
568709001932	substrate binding pocket [chemical binding]; other site
568709001933	dimerization interface [polypeptide binding]; other site
568709001934	lipoate-protein ligase B; Provisional; Region: PRK14342
568709001935	hypothetical protein; Provisional; Region: PRK04998
568709001936	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
568709001937	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
568709001938	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
568709001939	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
568709001940	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
568709001941	cell wall shape-determining protein; Provisional; Region: PRK10794
568709001942	penicillin-binding protein 2; Provisional; Region: PRK10795
568709001943	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
568709001944	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
568709001945	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
568709001946	ribosome-associated protein; Provisional; Region: PRK11538
568709001947	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568709001948	catalytic core [active]
568709001949	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
568709001950	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709001951	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709001952	homodimer interface [polypeptide binding]; other site
568709001953	catalytic residue [active]
568709001954	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
568709001955	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
568709001956	active site
568709001957	(T/H)XGH motif; other site
568709001958	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
568709001959	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
568709001960	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
568709001961	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
568709001962	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
568709001963	HIGH motif; other site
568709001964	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
568709001965	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
568709001966	active site
568709001967	KMSKS motif; other site
568709001968	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
568709001969	tRNA binding surface [nucleotide binding]; other site
568709001970	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
568709001971	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
568709001972	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
568709001973	Propionate catabolism activator; Region: PrpR_N; pfam06506
568709001974	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
568709001975	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709001976	Walker A motif; other site
568709001977	ATP binding site [chemical binding]; other site
568709001978	Walker B motif; other site
568709001979	arginine finger; other site
568709001980	hypothetical protein; Provisional; Region: PRK11032
568709001981	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
568709001982	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
568709001983	Sel1-like repeats; Region: SEL1; smart00671
568709001984	Sel1-like repeats; Region: SEL1; smart00671
568709001985	Sel1-like repeats; Region: SEL1; smart00671
568709001986	Sel1-like repeats; Region: SEL1; smart00671
568709001987	Sel1-like repeats; Region: SEL1; smart00671
568709001988	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
568709001989	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
568709001990	HSP70 interaction site [polypeptide binding]; other site
568709001992	DnaJ domain; Region: DnaJ; pfam00226
568709001993	HSP70 interaction site [polypeptide binding]; other site
568709001994	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
568709001995	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
568709001996	nucleotide binding site [chemical binding]; other site
568709001997	putative NEF/HSP70 interaction site [polypeptide binding]; other site
568709001998	SBD interface [polypeptide binding]; other site
568709001999	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
568709002000	active site
568709002001	tetramer interface [polypeptide binding]; other site
568709002002	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
568709002003	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
568709002004	Walker A/P-loop; other site
568709002005	ATP binding site [chemical binding]; other site
568709002006	Q-loop/lid; other site
568709002007	ABC transporter signature motif; other site
568709002008	Walker B; other site
568709002009	D-loop; other site
568709002010	H-loop/switch region; other site
568709002011	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568709002012	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709002013	dimer interface [polypeptide binding]; other site
568709002014	conserved gate region; other site
568709002015	putative PBP binding loops; other site
568709002016	ABC-ATPase subunit interface; other site
568709002017	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568709002018	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709002019	dimer interface [polypeptide binding]; other site
568709002020	conserved gate region; other site
568709002021	putative PBP binding loops; other site
568709002022	ABC-ATPase subunit interface; other site
568709002023	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
568709002024	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709002025	substrate binding pocket [chemical binding]; other site
568709002026	membrane-bound complex binding site; other site
568709002027	hinge residues; other site
568709002028	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
568709002029	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
568709002030	putative active site [active]
568709002031	catalytic triad [active]
568709002032	putative dimer interface [polypeptide binding]; other site
568709002033	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
568709002034	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
568709002035	Transporter associated domain; Region: CorC_HlyC; smart01091
568709002036	metal-binding heat shock protein; Provisional; Region: PRK00016
568709002037	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
568709002038	PhoH-like protein; Region: PhoH; pfam02562
568709002039	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
568709002040	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
568709002041	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709002042	FeS/SAM binding site; other site
568709002043	TRAM domain; Region: TRAM; pfam01938
568709002044	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
568709002045	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
568709002046	asparagine synthetase B; Provisional; Region: asnB; PRK09431
568709002047	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
568709002048	active site
568709002049	dimer interface [polypeptide binding]; other site
568709002050	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
568709002051	Ligand Binding Site [chemical binding]; other site
568709002052	Molecular Tunnel; other site
568709002053	UMP phosphatase; Provisional; Region: PRK10444
568709002054	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709002055	active site
568709002056	motif I; other site
568709002057	motif II; other site
568709002058	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709002059	MarR family; Region: MarR; pfam01047
568709002060	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
568709002061	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568709002062	nucleotide binding site [chemical binding]; other site
568709002063	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
568709002064	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
568709002065	active site
568709002066	dimer interface [polypeptide binding]; other site
568709002067	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
568709002068	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
568709002069	active site
568709002070	trimer interface [polypeptide binding]; other site
568709002071	allosteric site; other site
568709002072	active site lid [active]
568709002073	hexamer (dimer of trimers) interface [polypeptide binding]; other site
568709002074	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
568709002075	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568709002076	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568709002077	active site turn [active]
568709002078	phosphorylation site [posttranslational modification]
568709002079	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
568709002080	HPr interaction site; other site
568709002081	glycerol kinase (GK) interaction site [polypeptide binding]; other site
568709002082	active site
568709002083	phosphorylation site [posttranslational modification]
568709002084	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
568709002085	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
568709002086	active site
568709002087	HIGH motif; other site
568709002088	nucleotide binding site [chemical binding]; other site
568709002089	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
568709002090	KMSKS motif; other site
568709002091	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
568709002092	outer membrane porin, OprD family; Region: OprD; pfam03573
568709002093	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
568709002094	YbfN-like lipoprotein; Region: YbfN; pfam13982
568709002095	citrate-proton symporter; Provisional; Region: PRK15075
568709002096	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709002097	putative substrate translocation pore; other site
568709002098	tricarballylate utilization protein B; Provisional; Region: PRK15033
568709002099	tricarballylate dehydrogenase; Validated; Region: PRK08274
568709002100	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568709002101	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709002102	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709002103	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
568709002104	putative dimerization interface [polypeptide binding]; other site
568709002105	ferric uptake regulator; Provisional; Region: fur; PRK09462
568709002106	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
568709002107	metal binding site 2 [ion binding]; metal-binding site
568709002108	putative DNA binding helix; other site
568709002109	metal binding site 1 [ion binding]; metal-binding site
568709002110	dimer interface [polypeptide binding]; other site
568709002111	structural Zn2+ binding site [ion binding]; other site
568709002112	flavodoxin FldA; Validated; Region: PRK09267
568709002113	LexA regulated protein; Provisional; Region: PRK11675
568709002114	acyl-CoA esterase; Provisional; Region: PRK10673
568709002115	PGAP1-like protein; Region: PGAP1; pfam07819
568709002116	replication initiation regulator SeqA; Provisional; Region: PRK11187
568709002117	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
568709002118	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
568709002119	active site
568709002120	substrate binding site [chemical binding]; other site
568709002121	metal binding site [ion binding]; metal-binding site
568709002122	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
568709002123	putrescine transporter; Provisional; Region: potE; PRK10655
568709002124	ornithine decarboxylase; Provisional; Region: PRK13578
568709002125	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
568709002126	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
568709002127	homodimer interface [polypeptide binding]; other site
568709002128	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709002129	catalytic residue [active]
568709002130	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
568709002131	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
568709002132	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709002133	active site
568709002134	phosphorylation site [posttranslational modification]
568709002135	intermolecular recognition site; other site
568709002136	dimerization interface [polypeptide binding]; other site
568709002137	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709002138	DNA binding site [nucleotide binding]
568709002139	sensor protein KdpD; Provisional; Region: PRK10490
568709002140	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
568709002141	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
568709002142	Ligand Binding Site [chemical binding]; other site
568709002143	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
568709002144	GAF domain; Region: GAF_3; pfam13492
568709002145	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709002146	dimer interface [polypeptide binding]; other site
568709002147	phosphorylation site [posttranslational modification]
568709002148	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709002149	ATP binding site [chemical binding]; other site
568709002150	Mg2+ binding site [ion binding]; other site
568709002151	G-X-G motif; other site
568709002152	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
568709002153	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
568709002154	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568709002155	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
568709002156	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
568709002157	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
568709002158	DNA photolyase; Region: DNA_photolyase; pfam00875
568709002159	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
568709002160	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709002161	putative substrate translocation pore; other site
568709002162	POT family; Region: PTR2; pfam00854
568709002163	Uncharacterized conserved protein [Function unknown]; Region: COG0327
568709002164	metal-binding protein; Provisional; Region: PRK10799
568709002165	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
568709002166	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
568709002167	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
568709002168	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
568709002169	putative active site [active]
568709002170	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
568709002171	active site
568709002172	DNA binding site [nucleotide binding]
568709002173	Int/Topo IB signature motif; other site
568709002174	Note the premature stop codon following codon 159
568709002175	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
568709002176	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568709002177	active site
568709002178	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
568709002179	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568709002180	putative ADP-binding pocket [chemical binding]; other site
568709002181	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
568709002182	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
568709002183	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
568709002184	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
568709002185	Walker A/P-loop; other site
568709002186	ATP binding site [chemical binding]; other site
568709002187	Q-loop/lid; other site
568709002188	ABC transporter signature motif; other site
568709002189	Walker B; other site
568709002190	D-loop; other site
568709002191	H-loop/switch region; other site
568709002192	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
568709002193	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568709002194	active site
568709002195	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
568709002196	active site
568709002197	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
568709002198	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
568709002199	endonuclease VIII; Provisional; Region: PRK10445
568709002200	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
568709002201	DNA binding site [nucleotide binding]
568709002202	catalytic residue [active]
568709002203	putative catalytic residues [active]
568709002204	H2TH interface [polypeptide binding]; other site
568709002205	intercalation triad [nucleotide binding]; other site
568709002206	substrate specificity determining residue; other site
568709002207	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
568709002208	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
568709002209	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
568709002210	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
568709002211	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
568709002212	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
568709002213	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
568709002214	dimer interface [polypeptide binding]; other site
568709002215	active site
568709002216	citrylCoA binding site [chemical binding]; other site
568709002217	NADH binding [chemical binding]; other site
568709002218	cationic pore residues; other site
568709002219	oxalacetate/citrate binding site [chemical binding]; other site
568709002220	coenzyme A binding site [chemical binding]; other site
568709002221	catalytic triad [active]
568709002222	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
568709002223	Iron-sulfur protein interface; other site
568709002224	proximal quinone binding site [chemical binding]; other site
568709002225	SdhD (CybS) interface [polypeptide binding]; other site
568709002226	proximal heme binding site [chemical binding]; other site
568709002227	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
568709002228	SdhC subunit interface [polypeptide binding]; other site
568709002229	proximal heme binding site [chemical binding]; other site
568709002230	cardiolipin binding site; other site
568709002231	Iron-sulfur protein interface; other site
568709002232	proximal quinone binding site [chemical binding]; other site
568709002233	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
568709002234	L-aspartate oxidase; Provisional; Region: PRK06175
568709002235	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
568709002236	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
568709002237	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
568709002238	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
568709002239	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
568709002240	TPP-binding site [chemical binding]; other site
568709002241	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
568709002242	dimer interface [polypeptide binding]; other site
568709002243	PYR/PP interface [polypeptide binding]; other site
568709002244	TPP binding site [chemical binding]; other site
568709002245	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
568709002246	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
568709002247	E3 interaction surface; other site
568709002248	lipoyl attachment site [posttranslational modification]; other site
568709002249	e3 binding domain; Region: E3_binding; pfam02817
568709002250	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
568709002251	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
568709002252	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
568709002253	CoA-ligase; Region: Ligase_CoA; pfam00549
568709002254	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
568709002255	CoA binding domain; Region: CoA_binding; smart00881
568709002256	CoA-ligase; Region: Ligase_CoA; pfam00549
568709002257	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
568709002258	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
568709002259	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
568709002260	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
568709002261	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
568709002262	hypothetical protein; Provisional; Region: PRK10588
568709002263	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
568709002264	active site
568709002265	colicin uptake protein TolQ; Provisional; Region: PRK10801
568709002266	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
568709002267	colicin uptake protein TolR; Provisional; Region: PRK11024
568709002268	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
568709002269	TolA C-terminal; Region: TolA; pfam06519
568709002270	translocation protein TolB; Provisional; Region: tolB; PRK03629
568709002271	TolB amino-terminal domain; Region: TolB_N; pfam04052
568709002272	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
568709002273	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
568709002274	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
568709002275	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
568709002276	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
568709002277	ligand binding site [chemical binding]; other site
568709002278	tol-pal system protein YbgF; Provisional; Region: PRK10803
568709002279	Tetratricopeptide repeat; Region: TPR_6; pfam13174
568709002280	Tetratricopeptide repeat; Region: TPR_6; pfam13174
568709002281	quinolinate synthetase; Provisional; Region: PRK09375
568709002282	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
568709002283	zinc transporter ZitB; Provisional; Region: PRK03557
568709002284	YbgS-like protein; Region: YbgS; pfam13985
568709002285	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
568709002286	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
568709002287	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain [Energy production and conversion]; Region: FumA; COG1838
568709002288	fumarate hydratase; Provisional; Region: PRK06246
568709002289	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709002290	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709002291	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568709002292	dimerization interface [polypeptide binding]; other site
568709002293	cell density-dependent motility repressor; Provisional; Region: PRK10082
568709002294	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709002295	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568709002296	dimerization interface [polypeptide binding]; other site
568709002297	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
568709002298	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
568709002299	transmembrane helices; other site
568709002300	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
568709002301	oxaloacetate decarboxylase; Provisional; Region: PRK14040
568709002302	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
568709002303	active site
568709002304	catalytic residues [active]
568709002305	metal binding site [ion binding]; metal-binding site
568709002306	homodimer binding site [polypeptide binding]; other site
568709002307	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
568709002308	carboxyltransferase (CT) interaction site; other site
568709002309	biotinylation site [posttranslational modification]; other site
568709002310	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
568709002311	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
568709002312	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
568709002313	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
568709002314	dimer interface [polypeptide binding]; other site
568709002315	putative PBP binding regions; other site
568709002316	ABC-ATPase subunit  interface; other site
568709002317	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
568709002318	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
568709002319	Walker A/P-loop; other site
568709002320	ATP binding site [chemical binding]; other site
568709002321	Q-loop/lid; other site
568709002322	ABC transporter signature motif; other site
568709002323	Walker B; other site
568709002324	D-loop; other site
568709002325	H-loop/switch region; other site
568709002326	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568709002327	catalytic core [active]
568709002328	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568709002329	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
568709002330	active site
568709002331	catalytic residues [active]
568709002332	galactokinase; Provisional; Region: PRK05101
568709002333	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
568709002334	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
568709002335	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
568709002336	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
568709002337	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
568709002338	dimer interface [polypeptide binding]; other site
568709002339	active site
568709002340	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
568709002341	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
568709002342	NAD binding site [chemical binding]; other site
568709002343	homodimer interface [polypeptide binding]; other site
568709002344	active site
568709002345	substrate binding site [chemical binding]; other site
568709002346	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
568709002347	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
568709002348	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709002349	Walker A/P-loop; other site
568709002350	ATP binding site [chemical binding]; other site
568709002351	Q-loop/lid; other site
568709002352	ABC transporter signature motif; other site
568709002353	Walker B; other site
568709002354	D-loop; other site
568709002355	H-loop/switch region; other site
568709002356	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709002357	Walker A/P-loop; other site
568709002358	ATP binding site [chemical binding]; other site
568709002359	Q-loop/lid; other site
568709002360	ABC transporter signature motif; other site
568709002361	Walker B; other site
568709002362	D-loop; other site
568709002363	H-loop/switch region; other site
568709002364	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
568709002365	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
568709002366	molybdenum-pterin binding domain; Region: Mop; TIGR00638
568709002367	TOBE domain; Region: TOBE; pfam03459
568709002368	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
568709002369	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
568709002370	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709002371	substrate binding pocket [chemical binding]; other site
568709002372	membrane-bound complex binding site; other site
568709002373	hinge residues; other site
568709002374	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
568709002375	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709002376	dimer interface [polypeptide binding]; other site
568709002377	conserved gate region; other site
568709002378	putative PBP binding loops; other site
568709002379	ABC-ATPase subunit interface; other site
568709002380	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
568709002381	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709002382	Walker A/P-loop; other site
568709002383	ATP binding site [chemical binding]; other site
568709002384	Q-loop/lid; other site
568709002385	ABC transporter signature motif; other site
568709002386	Walker B; other site
568709002387	D-loop; other site
568709002388	H-loop/switch region; other site
568709002389	molybdenum-pterin binding domain; Region: Mop; TIGR00638
568709002390	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
568709002391	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709002392	active site
568709002393	motif I; other site
568709002394	motif II; other site
568709002395	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709002396	6-phosphogluconolactonase; Provisional; Region: PRK11028
568709002397	acyl-CoA thioesterase; Provisional; Region: PRK10531
568709002398	putative pectinesterase; Region: PLN02432; cl01911
568709002399	imidazolonepropionase; Validated; Region: PRK09356
568709002400	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
568709002401	active site
568709002402	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
568709002403	putative active site [active]
568709002404	putative metal binding site [ion binding]; other site
568709002405	histidine utilization repressor; Provisional; Region: PRK14999
568709002406	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709002407	DNA-binding site [nucleotide binding]; DNA binding site
568709002408	UTRA domain; Region: UTRA; pfam07702
568709002409	urocanate hydratase; Provisional; Region: PRK05414
568709002410	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
568709002411	active sites [active]
568709002412	tetramer interface [polypeptide binding]; other site
568709002413	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
568709002414	substrate binding site [chemical binding]; other site
568709002415	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
568709002416	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
568709002417	inhibitor-cofactor binding pocket; inhibition site
568709002418	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709002419	catalytic residue [active]
568709002420	biotin synthase; Provisional; Region: PRK15108
568709002421	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709002422	FeS/SAM binding site; other site
568709002423	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
568709002424	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
568709002425	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
568709002426	substrate-cofactor binding pocket; other site
568709002427	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709002428	catalytic residue [active]
568709002429	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
568709002430	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709002431	S-adenosylmethionine binding site [chemical binding]; other site
568709002432	AAA domain; Region: AAA_26; pfam13500
568709002433	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
568709002434	excinuclease ABC subunit B; Provisional; Region: PRK05298
568709002435	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568709002436	ATP binding site [chemical binding]; other site
568709002437	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709002438	nucleotide binding region [chemical binding]; other site
568709002439	ATP-binding site [chemical binding]; other site
568709002440	Ultra-violet resistance protein B; Region: UvrB; pfam12344
568709002441	UvrB/uvrC motif; Region: UVR; pfam02151
568709002442	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
568709002443	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
568709002444	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
568709002445	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
568709002446	Leucine-rich repeats; other site
568709002447	Substrate binding site [chemical binding]; other site
568709002448	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
568709002449	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
568709002450	putative substrate binding pocket [chemical binding]; other site
568709002451	dimer interface [polypeptide binding]; other site
568709002452	phosphate binding site [ion binding]; other site
568709002453	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
568709002454	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709002455	FeS/SAM binding site; other site
568709002456	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
568709002457	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
568709002458	MPT binding site; other site
568709002459	trimer interface [polypeptide binding]; other site
568709002460	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
568709002461	trimer interface [polypeptide binding]; other site
568709002462	dimer interface [polypeptide binding]; other site
568709002463	putative active site [active]
568709002464	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
568709002465	MoaE interaction surface [polypeptide binding]; other site
568709002466	MoeB interaction surface [polypeptide binding]; other site
568709002467	thiocarboxylated glycine; other site
568709002468	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
568709002469	MoaE homodimer interface [polypeptide binding]; other site
568709002470	MoaD interaction [polypeptide binding]; other site
568709002471	active site residues [active]
568709002472	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
568709002473	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
568709002474	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
568709002475	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
568709002476	Predicted integral membrane protein [Function unknown]; Region: COG0392
568709002477	cardiolipin synthase 2; Provisional; Region: PRK11263
568709002478	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
568709002479	putative active site [active]
568709002480	catalytic site [active]
568709002481	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
568709002482	putative active site [active]
568709002483	catalytic site [active]
568709002484	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
568709002485	putative catalytic site [active]
568709002486	putative metal binding site [ion binding]; other site
568709002487	putative phosphate binding site [ion binding]; other site
568709002488	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
568709002489	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
568709002490	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
568709002491	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
568709002492	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
568709002493	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
568709002494	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568709002495	Walker A/P-loop; other site
568709002496	ATP binding site [chemical binding]; other site
568709002497	Q-loop/lid; other site
568709002498	ABC transporter signature motif; other site
568709002499	Walker B; other site
568709002500	D-loop; other site
568709002501	H-loop/switch region; other site
568709002502	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
568709002503	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568709002504	Walker A/P-loop; other site
568709002505	ATP binding site [chemical binding]; other site
568709002506	Q-loop/lid; other site
568709002507	ABC transporter signature motif; other site
568709002508	Walker B; other site
568709002509	D-loop; other site
568709002510	H-loop/switch region; other site
568709002511	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
568709002512	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
568709002513	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709002514	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
568709002515	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709002516	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
568709002517	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
568709002518	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
568709002519	ATP binding site [chemical binding]; other site
568709002520	Mg++ binding site [ion binding]; other site
568709002521	motif III; other site
568709002522	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709002523	nucleotide binding region [chemical binding]; other site
568709002524	ATP-binding site [chemical binding]; other site
568709002525	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
568709002526	DEAD_2; Region: DEAD_2; pfam06733
568709002527	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
568709002528	glycosyl transferase family protein; Provisional; Region: PRK08136
568709002529	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
568709002530	hypothetical protein; Provisional; Region: PRK10259
568709002531	hypothetical protein; Provisional; Region: PRK11019
568709002532	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
568709002533	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
568709002534	putative mechanosensitive channel protein; Provisional; Region: PRK11465
568709002535	Mechanosensitive ion channel; Region: MS_channel; pfam00924
568709002536	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
568709002537	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
568709002538	Walker A/P-loop; other site
568709002539	ATP binding site [chemical binding]; other site
568709002540	Q-loop/lid; other site
568709002541	ABC transporter signature motif; other site
568709002542	Walker B; other site
568709002543	D-loop; other site
568709002544	H-loop/switch region; other site
568709002545	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568709002546	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709002547	dimer interface [polypeptide binding]; other site
568709002548	conserved gate region; other site
568709002549	putative PBP binding loops; other site
568709002550	ABC-ATPase subunit interface; other site
568709002551	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
568709002552	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709002553	substrate binding pocket [chemical binding]; other site
568709002554	membrane-bound complex binding site; other site
568709002555	hinge residues; other site
568709002556	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
568709002557	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
568709002558	dimerization interface [polypeptide binding]; other site
568709002559	DPS ferroxidase diiron center [ion binding]; other site
568709002560	ion pore; other site
568709002561	threonine and homoserine efflux system; Provisional; Region: PRK10532
568709002562	EamA-like transporter family; Region: EamA; pfam00892
568709002563	outer membrane protein X; Provisional; Region: ompX; PRK09408
568709002564	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
568709002565	Sulfatase; Region: Sulfatase; pfam00884
568709002566	manganese transport regulator MntR; Provisional; Region: PRK11050
568709002567	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
568709002568	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
568709002569	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
568709002570	transmembrane helices; other site
568709002571	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
568709002572	L,D-transpeptidase; Provisional; Region: PRK10260
568709002573	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
568709002574	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
568709002575	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568709002576	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709002577	Walker A/P-loop; other site
568709002578	ATP binding site [chemical binding]; other site
568709002579	ABC transporter signature motif; other site
568709002580	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568709002581	Walker B; other site
568709002582	ABC transporter; Region: ABC_tran_2; pfam12848
568709002583	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568709002584	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
568709002585	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709002586	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
568709002587	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
568709002588	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709002589	active site
568709002590	motif I; other site
568709002591	motif II; other site
568709002592	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709002593	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
568709002594	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
568709002595	dimer interface [polypeptide binding]; other site
568709002596	active site
568709002597	glycine loop; other site
568709002598	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
568709002599	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709002600	FeS/SAM binding site; other site
568709002601	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
568709002602	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
568709002603	ATP binding site [chemical binding]; other site
568709002604	substrate interface [chemical binding]; other site
568709002605	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
568709002606	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
568709002607	dimer interface [polypeptide binding]; other site
568709002608	putative functional site; other site
568709002609	putative MPT binding site; other site
568709002610	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
568709002611	catalytic nucleophile [active]
568709002612	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
568709002613	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709002614	Walker A/P-loop; other site
568709002615	ATP binding site [chemical binding]; other site
568709002616	Q-loop/lid; other site
568709002617	ABC transporter signature motif; other site
568709002618	Walker B; other site
568709002619	D-loop; other site
568709002620	H-loop/switch region; other site
568709002621	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
568709002622	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709002623	Walker A/P-loop; other site
568709002624	ATP binding site [chemical binding]; other site
568709002625	Q-loop/lid; other site
568709002626	ABC transporter signature motif; other site
568709002627	Walker B; other site
568709002628	D-loop; other site
568709002629	H-loop/switch region; other site
568709002630	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
568709002631	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
568709002632	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
568709002633	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
568709002634	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709002635	dimer interface [polypeptide binding]; other site
568709002636	conserved gate region; other site
568709002637	putative PBP binding loops; other site
568709002638	ABC-ATPase subunit interface; other site
568709002639	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
568709002640	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
568709002641	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709002642	dimer interface [polypeptide binding]; other site
568709002643	conserved gate region; other site
568709002644	putative PBP binding loops; other site
568709002645	ABC-ATPase subunit interface; other site
568709002646	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
568709002647	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
568709002648	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709002649	FeS/SAM binding site; other site
568709002650	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
568709002651	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
568709002652	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
568709002653	Ligand binding site [chemical binding]; other site
568709002654	Electron transfer flavoprotein domain; Region: ETF; pfam01012
568709002655	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
568709002656	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
568709002657	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
568709002658	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
568709002659	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
568709002660	active site
568709002661	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
568709002662	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568709002663	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
568709002664	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
568709002665	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709002666	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709002667	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421
568709002668	putative dimerization interface [polypeptide binding]; other site
568709002669	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
568709002670	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
568709002671	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
568709002672	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
568709002673	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
568709002674	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
568709002675	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
568709002676	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
568709002677	putative C-terminal domain interface [polypeptide binding]; other site
568709002678	putative GSH binding site (G-site) [chemical binding]; other site
568709002679	putative dimer interface [polypeptide binding]; other site
568709002680	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
568709002681	putative N-terminal domain interface [polypeptide binding]; other site
568709002682	putative dimer interface [polypeptide binding]; other site
568709002683	putative substrate binding pocket (H-site) [chemical binding]; other site
568709002684	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
568709002685	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
568709002686	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
568709002687	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
568709002688	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
568709002689	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709002690	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
568709002691	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
568709002692	active site
568709002693	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
568709002694	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709002695	putative substrate translocation pore; other site
568709002696	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
568709002697	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709002698	active site
568709002699	motif I; other site
568709002700	motif II; other site
568709002701	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709002702	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709002703	putative substrate translocation pore; other site
568709002704	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568709002705	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
568709002706	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709002707	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
568709002708	putative transporter; Provisional; Region: PRK04972
568709002709	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
568709002710	TrkA-C domain; Region: TrkA_C; pfam02080
568709002711	TrkA-C domain; Region: TrkA_C; pfam02080
568709002712	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
568709002713	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
568709002714	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
568709002715	GSH binding site [chemical binding]; other site
568709002716	catalytic residues [active]
568709002717	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
568709002718	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
568709002719	dimer interface [polypeptide binding]; other site
568709002720	FMN binding site [chemical binding]; other site
568709002721	NADPH bind site [chemical binding]; other site
568709002722	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
568709002723	RimK-like ATP-grasp domain; Region: RimK; pfam08443
568709002724	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
568709002725	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
568709002726	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
568709002727	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
568709002728	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709002729	Walker A/P-loop; other site
568709002730	ATP binding site [chemical binding]; other site
568709002731	Q-loop/lid; other site
568709002732	ABC transporter signature motif; other site
568709002733	Walker B; other site
568709002734	D-loop; other site
568709002735	H-loop/switch region; other site
568709002736	TOBE domain; Region: TOBE_2; pfam08402
568709002737	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
568709002738	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709002739	dimer interface [polypeptide binding]; other site
568709002740	conserved gate region; other site
568709002741	putative PBP binding loops; other site
568709002742	ABC-ATPase subunit interface; other site
568709002743	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
568709002744	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709002745	dimer interface [polypeptide binding]; other site
568709002746	conserved gate region; other site
568709002747	putative PBP binding loops; other site
568709002748	ABC-ATPase subunit interface; other site
568709002749	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
568709002750	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
568709002751	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709002752	S-adenosylmethionine binding site [chemical binding]; other site
568709002753	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
568709002754	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
568709002755	active site
568709002756	P-loop; other site
568709002757	phosphorylation site [posttranslational modification]
568709002758	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
568709002759	Sulfatase; Region: Sulfatase; cl17466
568709002760	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
568709002761	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709002762	substrate binding pocket [chemical binding]; other site
568709002763	membrane-bound complex binding site; other site
568709002764	hinge residues; other site
568709002765	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709002766	dimer interface [polypeptide binding]; other site
568709002767	conserved gate region; other site
568709002768	putative PBP binding loops; other site
568709002769	ABC-ATPase subunit interface; other site
568709002770	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568709002771	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709002772	dimer interface [polypeptide binding]; other site
568709002773	conserved gate region; other site
568709002774	putative PBP binding loops; other site
568709002775	ABC-ATPase subunit interface; other site
568709002776	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
568709002777	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709002778	substrate binding pocket [chemical binding]; other site
568709002779	membrane-bound complex binding site; other site
568709002780	hinge residues; other site
568709002781	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
568709002782	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709002783	Walker A/P-loop; other site
568709002784	ATP binding site [chemical binding]; other site
568709002785	Q-loop/lid; other site
568709002786	ABC transporter signature motif; other site
568709002787	Walker B; other site
568709002788	D-loop; other site
568709002789	H-loop/switch region; other site
568709002790	putative lipoprotein; Provisional; Region: PRK10533
568709002791	hypothetical protein; Provisional; Region: PRK02877
568709002792	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
568709002793	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
568709002794	amidase catalytic site [active]
568709002795	Zn binding residues [ion binding]; other site
568709002796	substrate binding site [chemical binding]; other site
568709002797	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
568709002798	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
568709002799	NAD(P) binding site [chemical binding]; other site
568709002800	active site
568709002801	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
568709002802	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
568709002803	putative NAD(P) binding site [chemical binding]; other site
568709002804	putative active site [active]
568709002805	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
568709002807	pyruvate dehydrogenase; Provisional; Region: PRK09124
568709002808	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
568709002809	PYR/PP interface [polypeptide binding]; other site
568709002810	dimer interface [polypeptide binding]; other site
568709002811	tetramer interface [polypeptide binding]; other site
568709002812	TPP binding site [chemical binding]; other site
568709002813	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568709002814	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
568709002815	TPP-binding site [chemical binding]; other site
568709002816	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
568709002817	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
568709002818	FAD binding pocket [chemical binding]; other site
568709002819	FAD binding motif [chemical binding]; other site
568709002820	phosphate binding motif [ion binding]; other site
568709002821	beta-alpha-beta structure motif; other site
568709002822	NAD binding pocket [chemical binding]; other site
568709002823	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
568709002824	catalytic loop [active]
568709002825	iron binding site [ion binding]; other site
568709002826	hybrid cluster protein; Provisional; Region: PRK05290
568709002827	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
568709002828	ACS interaction site; other site
568709002829	CODH interaction site; other site
568709002830	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
568709002831	hybrid metal cluster; other site
568709002832	Predicted membrane protein [Function unknown]; Region: COG2431
568709002833	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
568709002834	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
568709002835	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
568709002836	putative active site [active]
568709002837	putative metal-binding site [ion binding]; other site
568709002838	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
568709002839	macrolide transporter subunit MacA; Provisional; Region: PRK11578
568709002840	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
568709002841	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709002842	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
568709002843	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568709002844	Walker A/P-loop; other site
568709002845	ATP binding site [chemical binding]; other site
568709002846	Q-loop/lid; other site
568709002847	ABC transporter signature motif; other site
568709002848	Walker B; other site
568709002849	D-loop; other site
568709002850	H-loop/switch region; other site
568709002851	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
568709002852	FtsX-like permease family; Region: FtsX; pfam02687
568709002853	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
568709002854	DNA-binding site [nucleotide binding]; DNA binding site
568709002855	RNA-binding motif; other site
568709002856	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
568709002857	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
568709002858	Clp amino terminal domain; Region: Clp_N; pfam02861
568709002859	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709002860	Walker A motif; other site
568709002861	ATP binding site [chemical binding]; other site
568709002862	Walker B motif; other site
568709002863	arginine finger; other site
568709002864	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709002865	Walker A motif; other site
568709002866	ATP binding site [chemical binding]; other site
568709002867	Walker B motif; other site
568709002868	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
568709002869	Transposase IS200 like; Region: Y1_Tnp; pfam01797
568709002870	Integrase core domain; Region: rve; pfam00665
568709002871	Integrase core domain; Region: rve_3; pfam13683
568709002872	Helix-turn-helix domain; Region: HTH_28; pfam13518
568709002873	Isochorismatase family; Region: Isochorismatase; pfam00857
568709002874	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
568709002875	catalytic triad [active]
568709002876	dimer interface [polypeptide binding]; other site
568709002877	conserved cis-peptide bond; other site
568709002878	Pirin-related protein [General function prediction only]; Region: COG1741
568709002879	Pirin; Region: Pirin; pfam02678
568709002880	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
568709002881	LysR family transcriptional regulator; Provisional; Region: PRK14997
568709002882	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709002883	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
568709002884	putative effector binding pocket; other site
568709002885	putative dimerization interface [polypeptide binding]; other site
568709002886	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
568709002887	rRNA binding site [nucleotide binding]; other site
568709002888	predicted 30S ribosome binding site; other site
568709002889	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
568709002890	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
568709002891	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568709002892	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709002893	Walker A/P-loop; other site
568709002894	ATP binding site [chemical binding]; other site
568709002895	Q-loop/lid; other site
568709002896	ABC transporter signature motif; other site
568709002897	Walker B; other site
568709002898	D-loop; other site
568709002899	H-loop/switch region; other site
568709002900	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
568709002901	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568709002902	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709002903	Walker A/P-loop; other site
568709002904	ATP binding site [chemical binding]; other site
568709002905	Q-loop/lid; other site
568709002906	ABC transporter signature motif; other site
568709002907	Walker B; other site
568709002908	D-loop; other site
568709002909	H-loop/switch region; other site
568709002910	thioredoxin reductase; Provisional; Region: PRK10262
568709002911	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568709002912	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709002913	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
568709002914	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568709002915	putative DNA binding site [nucleotide binding]; other site
568709002916	putative Zn2+ binding site [ion binding]; other site
568709002917	AsnC family; Region: AsnC_trans_reg; pfam01037
568709002918	DNA translocase FtsK; Provisional; Region: PRK10263
568709002919	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
568709002920	DNA translocase FtsK; Provisional; Region: PRK10263
568709002921	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
568709002922	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
568709002923	periplasmic chaperone LolA; Region: lolA; TIGR00547
568709002924	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
568709002925	recombination factor protein RarA; Reviewed; Region: PRK13342
568709002926	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709002927	Walker A motif; other site
568709002928	ATP binding site [chemical binding]; other site
568709002929	Walker B motif; other site
568709002930	arginine finger; other site
568709002931	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
568709002932	seryl-tRNA synthetase; Provisional; Region: PRK05431
568709002933	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
568709002934	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
568709002935	dimer interface [polypeptide binding]; other site
568709002936	active site
568709002937	motif 1; other site
568709002938	motif 2; other site
568709002939	motif 3; other site
568709002940	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
568709002941	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
568709002942	putative [Fe4-S4] binding site [ion binding]; other site
568709002943	putative molybdopterin cofactor binding site [chemical binding]; other site
568709002944	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
568709002945	putative molybdopterin cofactor binding site; other site
568709002946	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
568709002947	4Fe-4S binding domain; Region: Fer4; pfam00037
568709002948	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
568709002949	putative MFS family transporter protein; Provisional; Region: PRK03633
568709002950	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709002951	putative substrate translocation pore; other site
568709002952	inner membrane transporter YjeM; Provisional; Region: PRK15238
568709002953	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
568709002954	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709002955	FeS/SAM binding site; other site
568709002956	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
568709002957	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
568709002958	Pyruvate formate lyase 1; Region: PFL1; cd01678
568709002959	coenzyme A binding site [chemical binding]; other site
568709002960	active site
568709002961	catalytic residues [active]
568709002962	glycine loop; other site
568709002963	formate transporter; Provisional; Region: PRK10805
568709002964	uncharacterized domain; Region: TIGR00702
568709002965	YcaO-like family; Region: YcaO; pfam02624
568709002966	Predicted membrane protein [Function unknown]; Region: COG2323
568709002967	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
568709002968	homodimer interface [polypeptide binding]; other site
568709002969	substrate-cofactor binding pocket; other site
568709002970	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709002971	catalytic residue [active]
568709002972	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
568709002973	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
568709002974	hinge; other site
568709002975	active site
568709002976	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
568709002977	cytidylate kinase; Provisional; Region: cmk; PRK00023
568709002978	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
568709002979	CMP-binding site; other site
568709002980	The sites determining sugar specificity; other site
568709002981	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
568709002982	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
568709002983	RNA binding site [nucleotide binding]; other site
568709002984	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
568709002985	RNA binding site [nucleotide binding]; other site
568709002986	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
568709002987	RNA binding site [nucleotide binding]; other site
568709002988	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
568709002989	RNA binding site [nucleotide binding]; other site
568709002990	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
568709002991	RNA binding site [nucleotide binding]; other site
568709002992	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
568709002993	IHF dimer interface [polypeptide binding]; other site
568709002994	IHF - DNA interface [nucleotide binding]; other site
568709002996	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
568709002997	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568709002998	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
568709002999	Walker A/P-loop; other site
568709003000	ATP binding site [chemical binding]; other site
568709003001	Q-loop/lid; other site
568709003002	ABC transporter signature motif; other site
568709003003	Walker B; other site
568709003004	D-loop; other site
568709003005	H-loop/switch region; other site
568709003006	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
568709003007	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
568709003008	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
568709003009	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
568709003010	hypothetical protein; Provisional; Region: PRK11827
568709003011	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
568709003012	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
568709003013	Ligand binding site; other site
568709003014	oligomer interface; other site
568709003015	hypothetical protein; Provisional; Region: PRK10593
568709003016	Uncharacterized conserved protein [Function unknown]; Region: COG1434
568709003017	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
568709003018	putative active site [active]
568709003019	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
568709003020	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709003021	S-adenosylmethionine binding site [chemical binding]; other site
568709003022	condesin subunit F; Provisional; Region: PRK05260
568709003023	condesin subunit E; Provisional; Region: PRK05256
568709003024	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
568709003025	P-loop containing region of AAA domain; Region: AAA_29; cl17516
568709003026	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
568709003027	murein L,D-transpeptidase; Provisional; Region: PRK10594
568709003028	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
568709003029	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
568709003030	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
568709003031	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
568709003032	Peptidase M15; Region: Peptidase_M15_3; cl01194
568709003033	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
568709003034	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
568709003035	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709003036	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709003037	homodimer interface [polypeptide binding]; other site
568709003038	catalytic residue [active]
568709003039	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
568709003040	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
568709003041	trimer interface [polypeptide binding]; other site
568709003042	eyelet of channel; other site
568709003043	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
568709003044	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
568709003045	putative dimer interface [polypeptide binding]; other site
568709003046	putative anticodon binding site; other site
568709003047	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
568709003048	homodimer interface [polypeptide binding]; other site
568709003049	motif 1; other site
568709003050	motif 2; other site
568709003051	active site
568709003052	motif 3; other site
568709003053	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
568709003054	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568709003055	putative DNA binding site [nucleotide binding]; other site
568709003056	putative Zn2+ binding site [ion binding]; other site
568709003057	AsnC family; Region: AsnC_trans_reg; pfam01037
568709003058	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
568709003059	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
568709003060	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568709003061	catalytic residue [active]
568709003062	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
568709003063	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
568709003064	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
568709003065	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
568709003066	active site
568709003067	only difference between Gifsy-2 (LT2) and this one is an insertion of 160-200 bps in the LT2 Gifsy-2 Tail fibre sequence STM1049
568709003068	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
568709003069	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
568709003070	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
568709003071	Int/Topo IB signature motif; other site
568709003072	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
568709003073	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
568709003074	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
568709003075	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
568709003076	Helix-turn-helix; Region: HTH_3; pfam01381
568709003077	Bacteriophage CII protein; Region: Phage_CII; pfam05269
568709003078	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
568709003079	primosomal protein DnaI; Provisional; Region: PRK02854
568709003080	putative replication protein; Provisional; Region: PRK12377
568709003081	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709003082	Walker A motif; other site
568709003083	ATP binding site [chemical binding]; other site
568709003084	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
568709003085	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
568709003086	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
568709003088	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
568709003089	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
568709003090	Antitermination protein; Region: Antiterm; pfam03589
568709003091	Antitermination protein; Region: Antiterm; pfam03589
568709003092	PipA protein; Region: PipA; pfam07108
568709003093	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
568709003094	catalytic residues [active]
568709003095	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
568709003096	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
568709003097	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
568709003098	Domain of unknown function (DUF1859); Region: DUF1859; pfam08948
568709003099	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
568709003100	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
568709003101	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
568709003102	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
568709003103	oligomer interface [polypeptide binding]; other site
568709003104	active site residues [active]
568709003105	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
568709003106	Uncharacterized conserved protein [Function unknown]; Region: COG5471
568709003107	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
568709003108	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
568709003109	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
568709003110	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
568709003111	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
568709003112	Minor tail protein T; Region: Phage_tail_T; cl05636
568709003113	Phage-related minor tail protein [Function unknown]; Region: COG5281
568709003114	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
568709003115	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
568709003116	Phage-related protein [Function unknown]; Region: COG4718
568709003117	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
568709003118	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
568709003119	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
568709003120	E-class dimer interface [polypeptide binding]; other site
568709003121	P-class dimer interface [polypeptide binding]; other site
568709003122	active site
568709003123	Cu2+ binding site [ion binding]; other site
568709003124	Zn2+ binding site [ion binding]; other site
568709003125	Phage-related protein [Function unknown]; Region: gp18; COG4672
568709003126	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
568709003127	MPN+ (JAMM) motif; other site
568709003128	Zinc-binding site [ion binding]; other site
568709003129	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
568709003130	NlpC/P60 family; Region: NLPC_P60; cl17555
568709003131	Phage-related protein, tail component [Function unknown]; Region: COG4723
568709003132	Phage-related protein, tail component [Function unknown]; Region: COG4733
568709003133	Putative phage tail protein; Region: Phage-tail_3; pfam13550
568709003134	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
568709003135	Interdomain contacts; other site
568709003136	Cytokine receptor motif; other site
568709003137	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
568709003138	Fibronectin type III protein; Region: DUF3672; pfam12421
568709003139	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
568709003140	Phage Tail Collar Domain; Region: Collar; pfam07484
568709003141	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
568709003142	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
568709003143	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
568709003144	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
568709003145	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
568709003146	hypothetical protein; Provisional; Region: PRK09951
568709003148	DinI-like family; Region: DinI; cl11630
568709003149	aminopeptidase N; Provisional; Region: pepN; PRK14015
568709003150	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
568709003151	active site
568709003152	Zn binding site [ion binding]; other site
568709003153	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
568709003154	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
568709003155	quinone interaction residues [chemical binding]; other site
568709003156	active site
568709003157	catalytic residues [active]
568709003158	FMN binding site [chemical binding]; other site
568709003159	substrate binding site [chemical binding]; other site
568709003160	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
568709003161	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
568709003162	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
568709003163	MOSC domain; Region: MOSC; pfam03473
568709003164	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
568709003165	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
568709003166	catalytic loop [active]
568709003167	iron binding site [ion binding]; other site
568709003168	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
568709003169	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
568709003170	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
568709003171	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709003172	S-adenosylmethionine binding site [chemical binding]; other site
568709003173	ABC transporter ATPase component; Reviewed; Region: PRK11147
568709003174	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709003175	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709003176	Walker A/P-loop; other site
568709003177	Walker A/P-loop; other site
568709003178	ATP binding site [chemical binding]; other site
568709003179	ATP binding site [chemical binding]; other site
568709003180	Q-loop/lid; other site
568709003181	Q-loop/lid; other site
568709003182	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568709003183	ABC transporter signature motif; other site
568709003184	Walker B; other site
568709003185	D-loop; other site
568709003186	ABC transporter; Region: ABC_tran_2; pfam12848
568709003187	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568709003188	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
568709003189	Paraquat-inducible protein A; Region: PqiA; pfam04403
568709003190	Paraquat-inducible protein A; Region: PqiA; pfam04403
568709003191	paraquat-inducible protein B; Provisional; Region: PRK10807
568709003192	mce related protein; Region: MCE; pfam02470
568709003193	mce related protein; Region: MCE; pfam02470
568709003194	mce related protein; Region: MCE; pfam02470
568709003195	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
568709003196	Protein of unknown function (DUF330); Region: DUF330; pfam03886
568709003197	ribosome modulation factor; Provisional; Region: PRK14563
568709003198	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
568709003199	active site 1 [active]
568709003200	dimer interface [polypeptide binding]; other site
568709003201	active site 2 [active]
568709003202	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
568709003203	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
568709003204	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
568709003205	outer membrane protein A; Reviewed; Region: PRK10808
568709003206	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
568709003207	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
568709003208	ligand binding site [chemical binding]; other site
568709003209	cell division inhibitor SulA; Region: sula; TIGR00623
568709003210	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
568709003211	TfoX C-terminal domain; Region: TfoX_C; pfam04994
568709003212	TIGR01666 family membrane protein; Region: YCCS
568709003213	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
568709003214	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
568709003215	Predicted membrane protein [Function unknown]; Region: COG3304
568709003216	Domain of unknown function (DUF307); Region: DUF307; pfam03733
568709003217	Domain of unknown function (DUF307); Region: DUF307; pfam03733
568709003218	DNA helicase IV; Provisional; Region: helD; PRK11054
568709003219	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
568709003220	Part of AAA domain; Region: AAA_19; pfam13245
568709003221	Family description; Region: UvrD_C_2; pfam13538
568709003222	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
568709003223	active site
568709003224	dimer interfaces [polypeptide binding]; other site
568709003225	catalytic residues [active]
568709003226	hypothetical protein; Provisional; Region: PRK03641
568709003227	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
568709003228	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
568709003229	heat shock protein HspQ; Provisional; Region: PRK14129
568709003230	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
568709003231	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
568709003232	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
568709003233	putative RNA binding site [nucleotide binding]; other site
568709003234	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709003235	S-adenosylmethionine binding site [chemical binding]; other site
568709003236	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
568709003237	substrate binding site [chemical binding]; other site
568709003238	Cupin domain; Region: Cupin_2; cl17218
568709003239	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568709003240	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709003241	acylphosphatase; Provisional; Region: PRK14426
568709003242	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
568709003243	sulfur transfer protein TusE; Provisional; Region: PRK11508
568709003244	YccA-like proteins; Region: YccA_like; cd10433
568709003245	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
568709003246	PipA protein; Region: PipA; pfam07108
568709003247	secreted effector protein PipB; Provisional; Region: PRK15197
568709003248	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
568709003249	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
568709003250	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
568709003251	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
568709003252	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
568709003253	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
568709003254	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
568709003255	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
568709003256	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
568709003257	HAMP domain; Region: HAMP; pfam00672
568709003258	dimerization interface [polypeptide binding]; other site
568709003259	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709003260	dimer interface [polypeptide binding]; other site
568709003261	phosphorylation site [posttranslational modification]
568709003262	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709003263	ATP binding site [chemical binding]; other site
568709003264	Mg2+ binding site [ion binding]; other site
568709003265	G-X-G motif; other site
568709003266	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
568709003267	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709003268	active site
568709003269	phosphorylation site [posttranslational modification]
568709003270	intermolecular recognition site; other site
568709003271	dimerization interface [polypeptide binding]; other site
568709003272	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709003273	DNA binding site [nucleotide binding]
568709003274	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
568709003275	active site
568709003276	homotetramer interface [polypeptide binding]; other site
568709003277	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
568709003278	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
568709003279	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
568709003280	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
568709003281	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
568709003282	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
568709003283	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
568709003284	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
568709003285	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
568709003286	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
568709003287	NAD binding site [chemical binding]; other site
568709003288	catalytic residues [active]
568709003289	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
568709003290	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
568709003291	putative active site [active]
568709003292	putative metal binding site [ion binding]; other site
568709003293	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
568709003294	putative substrate binding pocket [chemical binding]; other site
568709003295	trimer interface [polypeptide binding]; other site
568709003296	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
568709003297	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
568709003298	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709003299	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
568709003300	putative substrate translocation pore; other site
568709003301	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
568709003302	Cupin domain; Region: Cupin_2; pfam07883
568709003303	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709003304	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
568709003305	anti-adapter protein IraM; Provisional; Region: PRK09919
568709003306	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
568709003307	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
568709003308	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
568709003309	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
568709003310	HSP70 interaction site [polypeptide binding]; other site
568709003311	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
568709003312	substrate binding site [polypeptide binding]; other site
568709003313	dimer interface [polypeptide binding]; other site
568709003314	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
568709003315	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
568709003316	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
568709003317	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
568709003318	DsbD alpha interface [polypeptide binding]; other site
568709003319	catalytic residues [active]
568709003320	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
568709003321	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
568709003322	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
568709003323	catalytic residues [active]
568709003324	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
568709003325	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
568709003326	catalytic residues [active]
568709003327	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
568709003328	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
568709003329	catalytic core [active]
568709003330	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
568709003331	hypothetical protein; Provisional; Region: PRK10174
568709003332	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
568709003333	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
568709003334	General stress protein [General function prediction only]; Region: GsiB; COG3729
568709003335	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
568709003336	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709003337	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
568709003338	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
568709003339	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
568709003340	Predicted transcriptional regulator [Transcription]; Region: COG3905
568709003341	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
568709003342	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
568709003343	Glutamate binding site [chemical binding]; other site
568709003344	NAD binding site [chemical binding]; other site
568709003345	catalytic residues [active]
568709003346	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
568709003347	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
568709003348	Na binding site [ion binding]; other site
568709003349	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
568709003350	hypothetical protein; Provisional; Region: PRK10536
568709003351	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568709003352	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568709003353	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568709003354	putative active site [active]
568709003355	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
568709003356	Na binding site [ion binding]; other site
568709003357	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
568709003358	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
568709003359	putative active site cavity [active]
568709003360	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
568709003361	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
568709003362	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
568709003363	putative sialic acid transporter; Provisional; Region: PRK12307
568709003364	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709003365	putative substrate translocation pore; other site
568709003366	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568709003367	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568709003368	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
568709003369	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
568709003370	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
568709003371	putative ligand binding site [chemical binding]; other site
568709003372	NAD binding site [chemical binding]; other site
568709003373	dimerization interface [polypeptide binding]; other site
568709003374	catalytic site [active]
568709003375	putative hydrolase; Validated; Region: PRK09248
568709003376	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
568709003377	active site
568709003378	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
568709003379	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
568709003380	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
568709003381	curli assembly protein CsgF; Provisional; Region: PRK10050
568709003382	curli assembly protein CsgE; Provisional; Region: PRK10386
568709003383	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
568709003384	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709003385	DNA binding residues [nucleotide binding]
568709003386	dimerization interface [polypeptide binding]; other site
568709003387	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
568709003388	Curlin associated repeat; Region: Curlin_rpt; pfam07012
568709003389	Curlin associated repeat; Region: Curlin_rpt; pfam07012
568709003390	major curlin subunit; Provisional; Region: csgA; PRK10051
568709003391	Curlin associated repeat; Region: Curlin_rpt; pfam07012
568709003392	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
568709003393	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
568709003394	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
568709003395	putative ADP-ribose binding site [chemical binding]; other site
568709003396	putative active site [active]
568709003397	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
568709003398	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
568709003399	putative active site [active]
568709003400	catalytic site [active]
568709003401	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
568709003402	putative active site [active]
568709003403	catalytic site [active]
568709003404	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
568709003405	Acyltransferase family; Region: Acyl_transf_3; pfam01757
568709003406	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
568709003407	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
568709003408	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
568709003409	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
568709003410	Ligand binding site; other site
568709003411	DXD motif; other site
568709003412	lipoprotein; Provisional; Region: PRK10175
568709003413	secY/secA suppressor protein; Provisional; Region: PRK11467
568709003414	drug efflux system protein MdtG; Provisional; Region: PRK09874
568709003415	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709003416	putative substrate translocation pore; other site
568709003417	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
568709003418	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
568709003419	putative acyl-acceptor binding pocket; other site
568709003420	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
568709003421	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
568709003422	active site residue [active]
568709003423	hypothetical protein; Provisional; Region: PRK03757
568709003424	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
568709003425	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
568709003426	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
568709003427	hydroxyglutarate oxidase; Provisional; Region: PRK11728
568709003428	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
568709003429	DNA damage-inducible protein I; Provisional; Region: PRK10597
568709003430	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
568709003431	active site
568709003432	substrate binding pocket [chemical binding]; other site
568709003433	dimer interface [polypeptide binding]; other site
568709003434	lipoprotein; Provisional; Region: PRK10598
568709003435	glutaredoxin 2; Provisional; Region: PRK10387
568709003436	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
568709003437	C-terminal domain interface [polypeptide binding]; other site
568709003438	GSH binding site (G-site) [chemical binding]; other site
568709003439	catalytic residues [active]
568709003440	putative dimer interface [polypeptide binding]; other site
568709003441	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
568709003442	N-terminal domain interface [polypeptide binding]; other site
568709003443	multidrug resistance protein MdtH; Provisional; Region: PRK11646
568709003444	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709003445	putative substrate translocation pore; other site
568709003446	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
568709003447	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
568709003448	hypothetical protein; Provisional; Region: PRK11239
568709003449	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
568709003450	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568709003451	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568709003452	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
568709003453	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
568709003454	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
568709003455	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
568709003456	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
568709003457	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
568709003458	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
568709003459	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
568709003460	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
568709003461	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
568709003462	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
568709003463	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
568709003464	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
568709003465	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
568709003466	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
568709003467	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
568709003468	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
568709003469	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
568709003470	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
568709003471	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
568709003472	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
568709003473	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
568709003474	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
568709003475	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
568709003476	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
568709003477	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
568709003478	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
568709003479	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
568709003480	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
568709003481	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
568709003482	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
568709003483	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
568709003484	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
568709003485	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
568709003486	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
568709003487	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
568709003488	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
568709003489	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
568709003490	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
568709003491	homodimer interface [polypeptide binding]; other site
568709003492	oligonucleotide binding site [chemical binding]; other site
568709003493	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
568709003494	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
568709003495	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
568709003496	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568709003497	RNA binding surface [nucleotide binding]; other site
568709003498	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
568709003499	active site
568709003500	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
568709003501	Maf-like protein; Region: Maf; pfam02545
568709003502	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
568709003503	active site
568709003504	dimer interface [polypeptide binding]; other site
568709003505	hypothetical protein; Provisional; Region: PRK11193
568709003506	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
568709003507	putative phosphate acyltransferase; Provisional; Region: PRK05331
568709003508	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
568709003509	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
568709003510	dimer interface [polypeptide binding]; other site
568709003511	active site
568709003512	CoA binding pocket [chemical binding]; other site
568709003513	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
568709003514	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
568709003515	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
568709003516	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
568709003517	NAD(P) binding site [chemical binding]; other site
568709003518	homotetramer interface [polypeptide binding]; other site
568709003519	homodimer interface [polypeptide binding]; other site
568709003520	active site
568709003521	acyl carrier protein; Provisional; Region: acpP; PRK00982
568709003522	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
568709003523	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
568709003524	dimer interface [polypeptide binding]; other site
568709003525	active site
568709003526	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
568709003527	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
568709003528	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709003529	catalytic residue [active]
568709003530	conserved hypothetical protein, YceG family; Region: TIGR00247
568709003531	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
568709003532	dimerization interface [polypeptide binding]; other site
568709003533	thymidylate kinase; Validated; Region: tmk; PRK00698
568709003534	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
568709003535	TMP-binding site; other site
568709003536	ATP-binding site [chemical binding]; other site
568709003537	DNA polymerase III subunit delta'; Validated; Region: PRK07993
568709003538	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
568709003539	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
568709003540	active site
568709003541	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
568709003542	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568709003543	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568709003544	active site turn [active]
568709003545	phosphorylation site [posttranslational modification]
568709003546	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
568709003547	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
568709003548	N-terminal plug; other site
568709003549	ligand-binding site [chemical binding]; other site
568709003550	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
568709003551	nucleotide binding site/active site [active]
568709003552	HIT family signature motif; other site
568709003553	catalytic residue [active]
568709003554	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
568709003555	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
568709003556	putative dimer interface [polypeptide binding]; other site
568709003557	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
568709003558	thiamine kinase; Region: ycfN_thiK; TIGR02721
568709003559	thiamine kinase; Provisional; Region: thiK; PRK10271
568709003560	substrate binding site [chemical binding]; other site
568709003561	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
568709003562	beta-hexosaminidase; Provisional; Region: PRK05337
568709003563	hypothetical protein; Provisional; Region: PRK04940
568709003564	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
568709003565	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709003566	hypothetical protein; Provisional; Region: PRK11280
568709003567	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568709003568	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709003569	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
568709003570	L,D-transpeptidase; Provisional; Region: PRK10190
568709003571	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568709003572	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
568709003573	transcription-repair coupling factor; Provisional; Region: PRK10689
568709003574	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
568709003575	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568709003576	ATP binding site [chemical binding]; other site
568709003577	putative Mg++ binding site [ion binding]; other site
568709003578	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709003579	nucleotide binding region [chemical binding]; other site
568709003580	ATP-binding site [chemical binding]; other site
568709003581	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
568709003582	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
568709003583	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
568709003584	FtsX-like permease family; Region: FtsX; pfam02687
568709003585	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
568709003586	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
568709003587	Walker A/P-loop; other site
568709003588	ATP binding site [chemical binding]; other site
568709003589	Q-loop/lid; other site
568709003590	ABC transporter signature motif; other site
568709003591	Walker B; other site
568709003592	D-loop; other site
568709003593	H-loop/switch region; other site
568709003594	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
568709003595	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
568709003596	FtsX-like permease family; Region: FtsX; pfam02687
568709003597	fructokinase; Reviewed; Region: PRK09557
568709003598	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568709003599	nucleotide binding site [chemical binding]; other site
568709003600	NAD-dependent deacetylase; Provisional; Region: PRK00481
568709003601	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
568709003602	NAD+ binding site [chemical binding]; other site
568709003603	substrate binding site [chemical binding]; other site
568709003604	Zn binding site [ion binding]; other site
568709003605	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
568709003606	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
568709003607	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
568709003608	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709003609	dimer interface [polypeptide binding]; other site
568709003610	conserved gate region; other site
568709003611	putative PBP binding loops; other site
568709003612	ABC-ATPase subunit interface; other site
568709003613	Sif protein; Region: Sif; pfam06767
568709003614	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
568709003615	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709003616	dimer interface [polypeptide binding]; other site
568709003617	conserved gate region; other site
568709003618	putative PBP binding loops; other site
568709003619	ABC-ATPase subunit interface; other site
568709003620	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
568709003621	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709003622	Walker A/P-loop; other site
568709003623	ATP binding site [chemical binding]; other site
568709003624	Q-loop/lid; other site
568709003625	ABC transporter signature motif; other site
568709003626	Walker B; other site
568709003627	D-loop; other site
568709003628	H-loop/switch region; other site
568709003629	TOBE domain; Region: TOBE_2; pfam08402
568709003630	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
568709003631	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
568709003632	metal binding site [ion binding]; metal-binding site
568709003633	dimer interface [polypeptide binding]; other site
568709003634	Transposase IS200 like; Region: Y1_Tnp; pfam01797
568709003635	Uncharacterized conserved protein [Function unknown]; Region: COG2850
568709003636	Cupin-like domain; Region: Cupin_8; pfam13621
568709003637	sensor protein PhoQ; Provisional; Region: PRK10815
568709003638	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
568709003639	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
568709003640	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709003641	ATP binding site [chemical binding]; other site
568709003642	Mg2+ binding site [ion binding]; other site
568709003643	G-X-G motif; other site
568709003644	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
568709003645	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709003646	active site
568709003647	phosphorylation site [posttranslational modification]
568709003648	intermolecular recognition site; other site
568709003649	dimerization interface [polypeptide binding]; other site
568709003650	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709003651	DNA binding site [nucleotide binding]
568709003652	adenylosuccinate lyase; Provisional; Region: PRK09285
568709003653	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
568709003654	tetramer interface [polypeptide binding]; other site
568709003655	active site
568709003656	putative lysogenization regulator; Reviewed; Region: PRK00218
568709003657	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
568709003658	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
568709003659	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
568709003660	nudix motif; other site
568709003661	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
568709003662	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
568709003663	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
568709003664	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
568709003665	probable active site [active]
568709003666	isocitrate dehydrogenase; Validated; Region: PRK07362
568709003667	isocitrate dehydrogenase; Reviewed; Region: PRK07006
568709003668	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
568709003669	DinI-like family; Region: DinI; pfam06183
568709003670	Ricin-type beta-trefoil; Region: RICIN; smart00458
568709003671	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
568709003672	putative sugar binding sites [chemical binding]; other site
568709003673	Q-X-W motif; other site
568709003674	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
568709003675	DNA-binding site [nucleotide binding]; DNA binding site
568709003676	RNA-binding motif; other site
568709003677	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
568709003678	lysozyme inhibitor; Provisional; Region: PRK13791
568709003679	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
568709003680	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
568709003681	putative dimer interface [polypeptide binding]; other site
568709003682	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
568709003683	BNR repeat-like domain; Region: BNR_2; pfam13088
568709003684	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
568709003685	TRL-like protein family; Region: TRL; pfam13146
568709003686	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
568709003687	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
568709003688	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
568709003689	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709003690	dimer interface [polypeptide binding]; other site
568709003691	conserved gate region; other site
568709003692	ABC-ATPase subunit interface; other site
568709003693	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
568709003694	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709003695	dimer interface [polypeptide binding]; other site
568709003696	conserved gate region; other site
568709003697	putative PBP binding loops; other site
568709003698	ABC-ATPase subunit interface; other site
568709003699	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709003700	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
568709003701	Walker A/P-loop; other site
568709003702	ATP binding site [chemical binding]; other site
568709003703	Q-loop/lid; other site
568709003704	ABC transporter signature motif; other site
568709003705	Walker B; other site
568709003706	D-loop; other site
568709003707	H-loop/switch region; other site
568709003708	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709003709	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
568709003710	Walker A/P-loop; other site
568709003711	ATP binding site [chemical binding]; other site
568709003712	Q-loop/lid; other site
568709003713	ABC transporter signature motif; other site
568709003714	Walker B; other site
568709003715	D-loop; other site
568709003716	H-loop/switch region; other site
568709003717	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
568709003718	Mechanosensitive ion channel; Region: MS_channel; pfam00924
568709003719	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
568709003720	dimerization interface [polypeptide binding]; other site
568709003721	zinc/cadmium-binding protein; Provisional; Region: PRK10306
568709003722	aminoglycoside resistance protein; Provisional; Region: PRK13746
568709003723	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
568709003724	active site
568709003725	NTP binding site [chemical binding]; other site
568709003726	metal binding triad [ion binding]; metal-binding site
568709003727	antibiotic binding site [chemical binding]; other site
568709003728	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
568709003729	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709003730	DNA binding residues [nucleotide binding]
568709003731	transcriptional regulator MirA; Provisional; Region: PRK15043
568709003732	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
568709003733	DNA binding residues [nucleotide binding]
568709003734	dimer interface [polypeptide binding]; other site
568709003735	Pleckstrin homology-like domain; Region: PH-like; cl17171
568709003736	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
568709003737	chorismate mutase; Provisional; Region: PRK08055
568709003738	leucine export protein LeuE; Provisional; Region: PRK10958
568709003739	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
568709003740	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
568709003741	hypothetical protein; Provisional; Region: PRK10457
568709003742	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
568709003743	murein hydrolase B; Provisional; Region: PRK10760; cl17906
568709003744	Domain of unknown function (DUF333); Region: DUF333; pfam03891
568709003745	Uncharacterized conserved protein [Function unknown]; Region: COG3189
568709003746	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
568709003747	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709003748	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568709003749	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709003750	Predicted membrane protein [Function unknown]; Region: COG2707
568709003751	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
568709003752	putative deacylase active site [active]
568709003753	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
568709003754	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568709003755	metal binding site [ion binding]; metal-binding site
568709003756	active site
568709003757	I-site; other site
568709003758	hypothetical protein; Provisional; Region: PRK05325
568709003759	PrkA family serine protein kinase; Provisional; Region: PRK15455
568709003760	AAA ATPase domain; Region: AAA_16; pfam13191
568709003761	Walker A motif; other site
568709003762	ATP binding site [chemical binding]; other site
568709003763	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
568709003764	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
568709003765	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
568709003766	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709003767	FeS/SAM binding site; other site
568709003768	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
568709003769	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568709003770	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568709003771	active site
568709003772	catalytic tetrad [active]
568709003773	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
568709003774	active site
568709003775	phosphate binding residues; other site
568709003776	catalytic residues [active]
568709003777	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
568709003778	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
568709003779	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
568709003780	methionine sulfoxide reductase B; Provisional; Region: PRK00222
568709003781	SelR domain; Region: SelR; pfam01641
568709003782	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
568709003783	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
568709003784	Isochorismatase family; Region: Isochorismatase; pfam00857
568709003785	catalytic triad [active]
568709003786	metal binding site [ion binding]; metal-binding site
568709003787	conserved cis-peptide bond; other site
568709003788	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
568709003789	active site
568709003790	homodimer interface [polypeptide binding]; other site
568709003791	protease 4; Provisional; Region: PRK10949
568709003792	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
568709003793	tandem repeat interface [polypeptide binding]; other site
568709003794	oligomer interface [polypeptide binding]; other site
568709003795	active site residues [active]
568709003796	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
568709003797	tandem repeat interface [polypeptide binding]; other site
568709003798	oligomer interface [polypeptide binding]; other site
568709003799	active site residues [active]
568709003800	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
568709003801	putative FMN binding site [chemical binding]; other site
568709003802	selenophosphate synthetase; Provisional; Region: PRK00943
568709003803	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
568709003804	dimerization interface [polypeptide binding]; other site
568709003805	putative ATP binding site [chemical binding]; other site
568709003806	DNA topoisomerase III; Provisional; Region: PRK07726
568709003807	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
568709003808	active site
568709003809	putative interdomain interaction site [polypeptide binding]; other site
568709003810	putative metal-binding site [ion binding]; other site
568709003811	putative nucleotide binding site [chemical binding]; other site
568709003812	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
568709003813	domain I; other site
568709003814	DNA binding groove [nucleotide binding]
568709003815	phosphate binding site [ion binding]; other site
568709003816	domain II; other site
568709003817	domain III; other site
568709003818	nucleotide binding site [chemical binding]; other site
568709003819	catalytic site [active]
568709003820	domain IV; other site
568709003821	glutamate dehydrogenase; Provisional; Region: PRK09414
568709003822	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
568709003823	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
568709003824	NAD(P) binding site [chemical binding]; other site
568709003825	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
568709003826	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
568709003827	active site
568709003828	8-oxo-dGMP binding site [chemical binding]; other site
568709003829	nudix motif; other site
568709003830	metal binding site [ion binding]; metal-binding site
568709003831	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
568709003832	putative catalytic site [active]
568709003833	putative phosphate binding site [ion binding]; other site
568709003834	active site
568709003835	metal binding site A [ion binding]; metal-binding site
568709003836	DNA binding site [nucleotide binding]
568709003837	putative AP binding site [nucleotide binding]; other site
568709003838	putative metal binding site B [ion binding]; other site
568709003839	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
568709003840	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
568709003841	inhibitor-cofactor binding pocket; inhibition site
568709003842	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709003843	catalytic residue [active]
568709003844	arginine succinyltransferase; Provisional; Region: PRK10456
568709003845	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
568709003846	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
568709003847	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
568709003848	NAD(P) binding site [chemical binding]; other site
568709003849	catalytic residues [active]
568709003850	succinylarginine dihydrolase; Provisional; Region: PRK13281
568709003851	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
568709003852	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
568709003853	putative active site [active]
568709003854	Zn binding site [ion binding]; other site
568709003855	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
568709003856	dimer interface [polypeptide binding]; other site
568709003857	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
568709003858	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
568709003859	GIY-YIG motif/motif A; other site
568709003860	active site
568709003861	catalytic site [active]
568709003862	putative DNA binding site [nucleotide binding]; other site
568709003863	metal binding site [ion binding]; metal-binding site
568709003864	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
568709003865	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
568709003866	homodimer interface [polypeptide binding]; other site
568709003867	NAD binding pocket [chemical binding]; other site
568709003868	ATP binding pocket [chemical binding]; other site
568709003869	Mg binding site [ion binding]; other site
568709003870	active-site loop [active]
568709003871	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
568709003872	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
568709003873	active site
568709003874	P-loop; other site
568709003875	phosphorylation site [posttranslational modification]
568709003876	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
568709003877	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
568709003878	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
568709003879	methionine cluster; other site
568709003880	active site
568709003881	phosphorylation site [posttranslational modification]
568709003882	metal binding site [ion binding]; metal-binding site
568709003883	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
568709003884	Cupin domain; Region: Cupin_2; pfam07883
568709003885	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709003886	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
568709003887	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
568709003888	NAD binding site [chemical binding]; other site
568709003889	sugar binding site [chemical binding]; other site
568709003890	divalent metal binding site [ion binding]; other site
568709003891	tetramer (dimer of dimers) interface [polypeptide binding]; other site
568709003892	dimer interface [polypeptide binding]; other site
568709003893	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
568709003894	putative active site [active]
568709003895	YdjC motif; other site
568709003896	Mg binding site [ion binding]; other site
568709003897	putative homodimer interface [polypeptide binding]; other site
568709003898	hydroperoxidase II; Provisional; Region: katE; PRK11249
568709003899	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
568709003900	tetramer interface [polypeptide binding]; other site
568709003901	heme binding pocket [chemical binding]; other site
568709003902	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
568709003903	domain interactions; other site
568709003904	cell division modulator; Provisional; Region: PRK10113
568709003905	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
568709003906	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
568709003907	inner membrane protein; Provisional; Region: PRK11648
568709003908	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
568709003909	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
568709003910	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709003911	motif II; other site
568709003912	YniB-like protein; Region: YniB; pfam14002
568709003913	Phosphotransferase enzyme family; Region: APH; pfam01636
568709003914	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
568709003915	active site
568709003916	ATP binding site [chemical binding]; other site
568709003917	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
568709003918	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
568709003919	6-phosphofructokinase 2; Provisional; Region: PRK10294
568709003920	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
568709003921	putative substrate binding site [chemical binding]; other site
568709003922	putative ATP binding site [chemical binding]; other site
568709003923	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
568709003924	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
568709003925	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
568709003926	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
568709003927	active site
568709003928	substrate binding site [chemical binding]; other site
568709003929	Mg2+ binding site [ion binding]; other site
568709003930	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
568709003931	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
568709003932	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
568709003933	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
568709003934	active site
568709003935	dimer interface [polypeptide binding]; other site
568709003936	motif 1; other site
568709003937	motif 2; other site
568709003938	motif 3; other site
568709003939	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
568709003940	anticodon binding site; other site
568709003941	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
568709003942	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
568709003943	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
568709003944	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
568709003945	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
568709003946	23S rRNA binding site [nucleotide binding]; other site
568709003947	L21 binding site [polypeptide binding]; other site
568709003948	L13 binding site [polypeptide binding]; other site
568709003949	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
568709003950	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
568709003951	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
568709003952	dimer interface [polypeptide binding]; other site
568709003953	motif 1; other site
568709003954	active site
568709003955	motif 2; other site
568709003956	motif 3; other site
568709003957	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
568709003958	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
568709003959	putative tRNA-binding site [nucleotide binding]; other site
568709003960	B3/4 domain; Region: B3_4; pfam03483
568709003961	tRNA synthetase B5 domain; Region: B5; smart00874
568709003962	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
568709003963	dimer interface [polypeptide binding]; other site
568709003964	motif 1; other site
568709003965	motif 3; other site
568709003966	motif 2; other site
568709003967	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
568709003968	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
568709003969	IHF dimer interface [polypeptide binding]; other site
568709003970	IHF - DNA interface [nucleotide binding]; other site
568709003971	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
568709003972	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
568709003973	ABC-ATPase subunit  interface; other site
568709003974	dimer interface [polypeptide binding]; other site
568709003975	putative PBP binding regions; other site
568709003976	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
568709003977	catalytic residues [active]
568709003978	dimer interface [polypeptide binding]; other site
568709003979	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
568709003980	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
568709003981	Walker A/P-loop; other site
568709003982	ATP binding site [chemical binding]; other site
568709003983	Q-loop/lid; other site
568709003984	ABC transporter signature motif; other site
568709003985	Walker B; other site
568709003986	D-loop; other site
568709003987	H-loop/switch region; other site
568709003988	NlpC/P60 family; Region: NLPC_P60; pfam00877
568709003989	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
568709003990	Uncharacterized conserved protein [Function unknown]; Region: COG0397
568709003991	hypothetical protein; Validated; Region: PRK00029
568709003992	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
568709003993	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
568709003994	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
568709003995	PEP synthetase regulatory protein; Provisional; Region: PRK05339
568709003996	phosphoenolpyruvate synthase; Validated; Region: PRK06464
568709003997	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
568709003998	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
568709003999	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
568709004000	absent from CT18
568709004001	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
568709004002	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
568709004003	acyl-activating enzyme (AAE) consensus motif; other site
568709004004	putative AMP binding site [chemical binding]; other site
568709004005	putative active site [active]
568709004006	putative CoA binding site [chemical binding]; other site
568709004007	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
568709004008	oxidoreductase; Provisional; Region: PRK10015
568709004009	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
568709004010	Electron transfer flavoprotein domain; Region: ETF; smart00893
568709004011	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
568709004012	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
568709004013	Ligand binding site [chemical binding]; other site
568709004014	Electron transfer flavoprotein domain; Region: ETF; pfam01012
568709004015	Cupin domain; Region: Cupin_2; pfam07883
568709004016	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568709004017	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709004018	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
568709004019	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
568709004020	active site
568709004021	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
568709004022	Coenzyme A transferase; Region: CoA_trans; smart00882
568709004023	Coenzyme A transferase; Region: CoA_trans; cl17247
568709004024	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
568709004025	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
568709004026	active site
568709004027	catalytic residue [active]
568709004028	dimer interface [polypeptide binding]; other site
568709004029	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
568709004030	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
568709004031	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
568709004032	shikimate binding site; other site
568709004033	NAD(P) binding site [chemical binding]; other site
568709004035	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709004036	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568709004037	putative substrate translocation pore; other site
568709004038	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
568709004039	putative inner membrane protein; Provisional; Region: PRK10983
568709004040	Domain of unknown function DUF20; Region: UPF0118; pfam01594
568709004041	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
568709004042	FAD binding domain; Region: FAD_binding_4; pfam01565
568709004043	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
568709004044	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
568709004045	CoenzymeA binding site [chemical binding]; other site
568709004046	subunit interaction site [polypeptide binding]; other site
568709004047	PHB binding site; other site
568709004048	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
568709004049	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
568709004050	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
568709004051	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
568709004052	putative ABC transporter; Region: ycf24; CHL00085
568709004053	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
568709004054	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
568709004055	Walker A/P-loop; other site
568709004056	ATP binding site [chemical binding]; other site
568709004057	Q-loop/lid; other site
568709004058	ABC transporter signature motif; other site
568709004059	Walker B; other site
568709004060	D-loop; other site
568709004061	H-loop/switch region; other site
568709004062	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
568709004063	FeS assembly protein SufD; Region: sufD; TIGR01981
568709004064	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
568709004065	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
568709004066	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568709004067	catalytic residue [active]
568709004068	cysteine desufuration protein SufE; Provisional; Region: PRK09296
568709004069	L,D-transpeptidase; Provisional; Region: PRK10190
568709004070	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568709004071	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
568709004072	murein lipoprotein; Provisional; Region: PRK15396
568709004073	murein lipoprotein; Provisional; Region: PRK15396
568709004074	pyruvate kinase; Provisional; Region: PRK09206
568709004075	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
568709004076	active site
568709004077	domain interfaces; other site
568709004078	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
568709004079	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
568709004080	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
568709004081	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568709004082	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
568709004083	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709004084	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
568709004085	substrate binding site [chemical binding]; other site
568709004086	dimer interface [polypeptide binding]; other site
568709004087	ATP binding site [chemical binding]; other site
568709004088	tetrathionate reductase subunit A; Provisional; Region: PRK14991
568709004089	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
568709004090	putative [Fe4-S4] binding site [ion binding]; other site
568709004091	putative molybdopterin cofactor binding site [chemical binding]; other site
568709004092	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
568709004093	putative molybdopterin cofactor binding site; other site
568709004094	tetrathionate reductase subunit C; Provisional; Region: PRK14992
568709004095	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
568709004096	tetrathionate reductase subunit B; Provisional; Region: PRK14993
568709004097	4Fe-4S binding domain; Region: Fer4; pfam00037
568709004098	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
568709004099	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
568709004100	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568709004101	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709004102	dimer interface [polypeptide binding]; other site
568709004103	phosphorylation site [posttranslational modification]
568709004104	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709004105	ATP binding site [chemical binding]; other site
568709004106	Mg2+ binding site [ion binding]; other site
568709004107	G-X-G motif; other site
568709004108	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
568709004109	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709004110	active site
568709004111	phosphorylation site [posttranslational modification]
568709004112	intermolecular recognition site; other site
568709004113	dimerization interface [polypeptide binding]; other site
568709004114	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709004115	DNA binding residues [nucleotide binding]
568709004116	dimerization interface [polypeptide binding]; other site
568709004117	hypothetical protein; Provisional; Region: PRK10292
568709004118	Uncharacterized conserved protein [Function unknown]; Region: COG1683
568709004119	Uncharacterized conserved protein [Function unknown]; Region: COG3272
568709004120	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
568709004121	transcriptional regulator MirA; Provisional; Region: PRK15043
568709004122	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
568709004123	DNA binding residues [nucleotide binding]
568709004124	two component system sensor kinase SsrB; Provisional; Region: PRK15369
568709004125	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709004126	active site
568709004127	phosphorylation site [posttranslational modification]
568709004128	intermolecular recognition site; other site
568709004129	dimerization interface [polypeptide binding]; other site
568709004130	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709004131	DNA binding residues [nucleotide binding]
568709004132	dimerization interface [polypeptide binding]; other site
568709004133	two component system sensor kinase SsrA; Provisional; Region: PRK15347
568709004134	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709004135	dimerization interface [polypeptide binding]; other site
568709004136	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709004137	dimer interface [polypeptide binding]; other site
568709004138	phosphorylation site [posttranslational modification]
568709004139	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709004140	ATP binding site [chemical binding]; other site
568709004141	Mg2+ binding site [ion binding]; other site
568709004142	G-X-G motif; other site
568709004143	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709004144	active site
568709004145	phosphorylation site [posttranslational modification]
568709004146	intermolecular recognition site; other site
568709004147	dimerization interface [polypeptide binding]; other site
568709004148	pathogenicity island chaperone protein SpiC; Provisional; Region: PRK15368
568709004149	outer membrane secretin SsaC; Provisional; Region: PRK15346
568709004150	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
568709004151	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
568709004152	type III secretion system protein SsaD; Provisional; Region: PRK15367
568709004153	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
568709004154	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
568709004155	type III secretion system chaperone SseA; Provisional; Region: PRK15365
568709004156	pathogenicity island 2 effector protein SseB; Provisional; Region: PRK15364
568709004157	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
568709004158	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
568709004159	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
568709004160	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
568709004161	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
568709004162	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
568709004163	TPR motif; other site
568709004164	binding surface
568709004165	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
568709004166	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
568709004167	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
568709004168	type III secretion system protein SsaH; Provisional; Region: PRK15356
568709004169	type III secretion system protein SsaI; Provisional; Region: PRK15355
568709004170	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
568709004171	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
568709004172	type III secretion system protein SsaK; Provisional; Region: PRK15354
568709004173	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
568709004174	type III secretion system protein SsaL; Provisional; Region: PRK15345
568709004175	HrpJ-like domain; Region: HrpJ; pfam07201
568709004176	TyeA; Region: TyeA; cl07611
568709004177	type III secretion system protein SsaM; Provisional; Region: PRK15353
568709004178	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
568709004179	FHIPEP family; Region: FHIPEP; pfam00771
568709004180	type III secretion system ATPase SsaN; Validated; Region: PRK07594
568709004181	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
568709004182	Walker A motif; other site
568709004183	ATP binding site [chemical binding]; other site
568709004184	Walker B motif; other site
568709004185	type III secretion system protein SsaO; Provisional; Region: PRK15352
568709004186	type III secretion system protein SsaP; Provisional; Region: PRK15351
568709004187	type III secretion system protein SsaQ; Validated; Region: PRK08035
568709004188	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437
568709004189	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
568709004190	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
568709004191	type III secretion system protein SsaS; Provisional; Region: PRK15350
568709004192	type III secretion system protein SsaT; Provisional; Region: PRK15349
568709004193	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
568709004194	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
568709004195	multidrug efflux protein; Reviewed; Region: PRK01766
568709004196	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
568709004197	cation binding site [ion binding]; other site
568709004198	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
568709004199	Lumazine binding domain; Region: Lum_binding; pfam00677
568709004200	Lumazine binding domain; Region: Lum_binding; pfam00677
568709004201	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
568709004202	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709004203	S-adenosylmethionine binding site [chemical binding]; other site
568709004204	putative transporter; Provisional; Region: PRK11043
568709004205	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709004206	putative substrate translocation pore; other site
568709004207	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
568709004208	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709004209	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709004210	dimerization interface [polypeptide binding]; other site
568709004211	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
568709004212	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709004213	DNA binding site [nucleotide binding]
568709004214	domain linker motif; other site
568709004215	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
568709004216	dimerization interface [polypeptide binding]; other site
568709004217	ligand binding site [chemical binding]; other site
568709004218	superoxide dismutase; Provisional; Region: PRK10543
568709004219	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
568709004220	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
568709004221	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
568709004222	NlpC/P60 family; Region: NLPC_P60; pfam00877
568709004223	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
568709004224	putative GSH binding site [chemical binding]; other site
568709004225	catalytic residues [active]
568709004226	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
568709004227	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
568709004228	dimer interface [polypeptide binding]; other site
568709004229	catalytic site [active]
568709004230	putative active site [active]
568709004231	putative substrate binding site [chemical binding]; other site
568709004232	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
568709004233	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
568709004234	dimer interface [polypeptide binding]; other site
568709004235	active site
568709004236	metal binding site [ion binding]; metal-binding site
568709004237	glutathione binding site [chemical binding]; other site
568709004238	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
568709004239	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
568709004240	FMN binding site [chemical binding]; other site
568709004241	active site
568709004242	substrate binding site [chemical binding]; other site
568709004243	catalytic residue [active]
568709004244	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568709004245	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709004246	Predicted Fe-S protein [General function prediction only]; Region: COG3313
568709004247	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568709004248	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568709004249	active site
568709004250	catalytic tetrad [active]
568709004251	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
568709004252	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
568709004253	E-class dimer interface [polypeptide binding]; other site
568709004254	P-class dimer interface [polypeptide binding]; other site
568709004255	active site
568709004256	Cu2+ binding site [ion binding]; other site
568709004257	Zn2+ binding site [ion binding]; other site
568709004258	Fusaric acid resistance protein family; Region: FUSC; pfam04632
568709004259	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
568709004260	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
568709004261	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
568709004262	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709004263	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
568709004264	transcriptional regulator SlyA; Provisional; Region: PRK03573
568709004265	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
568709004266	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
568709004267	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
568709004268	lysozyme inhibitor; Provisional; Region: PRK11372
568709004269	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
568709004270	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
568709004271	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
568709004272	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
568709004273	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
568709004274	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
568709004275	active site
568709004276	HIGH motif; other site
568709004277	dimer interface [polypeptide binding]; other site
568709004278	KMSKS motif; other site
568709004279	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568709004280	RNA binding surface [nucleotide binding]; other site
568709004281	pyridoxamine kinase; Validated; Region: PRK05756
568709004282	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
568709004283	dimer interface [polypeptide binding]; other site
568709004284	pyridoxal binding site [chemical binding]; other site
568709004285	ATP binding site [chemical binding]; other site
568709004286	glutathionine S-transferase; Provisional; Region: PRK10542
568709004287	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
568709004288	C-terminal domain interface [polypeptide binding]; other site
568709004289	GSH binding site (G-site) [chemical binding]; other site
568709004290	dimer interface [polypeptide binding]; other site
568709004291	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
568709004292	dimer interface [polypeptide binding]; other site
568709004293	N-terminal domain interface [polypeptide binding]; other site
568709004294	substrate binding pocket (H-site) [chemical binding]; other site
568709004295	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
568709004296	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709004297	putative substrate translocation pore; other site
568709004298	POT family; Region: PTR2; pfam00854
568709004299	endonuclease III; Provisional; Region: PRK10702
568709004300	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
568709004301	minor groove reading motif; other site
568709004302	helix-hairpin-helix signature motif; other site
568709004303	substrate binding pocket [chemical binding]; other site
568709004304	active site
568709004305	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
568709004306	electron transport complex RsxE subunit; Provisional; Region: PRK12405
568709004307	electron transport complex protein RnfG; Validated; Region: PRK01908
568709004308	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
568709004309	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
568709004310	SLBB domain; Region: SLBB; pfam10531
568709004311	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
568709004312	electron transport complex protein RnfB; Provisional; Region: PRK05113
568709004313	Putative Fe-S cluster; Region: FeS; cl17515
568709004314	4Fe-4S binding domain; Region: Fer4; pfam00037
568709004315	electron transport complex protein RsxA; Provisional; Region: PRK05151
568709004316	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
568709004317	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
568709004318	putative oxidoreductase; Provisional; Region: PRK11579
568709004319	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568709004320	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
568709004321	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
568709004322	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
568709004323	active site
568709004324	purine riboside binding site [chemical binding]; other site
568709004325	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
568709004326	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
568709004327	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
568709004328	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
568709004329	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
568709004330	fumarate hydratase; Provisional; Region: PRK15389
568709004331	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
568709004332	Fumarase C-terminus; Region: Fumerase_C; pfam05683
568709004333	fumarate hydratase; Reviewed; Region: fumC; PRK00485
568709004334	Class II fumarases; Region: Fumarase_classII; cd01362
568709004335	active site
568709004336	tetramer interface [polypeptide binding]; other site
568709004337	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
568709004338	sensor protein RstB; Provisional; Region: PRK10604
568709004339	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709004340	dimerization interface [polypeptide binding]; other site
568709004341	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709004342	dimer interface [polypeptide binding]; other site
568709004343	phosphorylation site [posttranslational modification]
568709004344	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709004345	ATP binding site [chemical binding]; other site
568709004346	Mg2+ binding site [ion binding]; other site
568709004347	G-X-G motif; other site
568709004348	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
568709004349	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
568709004350	active site
568709004351	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
568709004352	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
568709004353	trimer interface [polypeptide binding]; other site
568709004354	eyelet of channel; other site
568709004355	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
568709004356	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709004357	active site
568709004358	phosphorylation site [posttranslational modification]
568709004359	intermolecular recognition site; other site
568709004360	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709004361	DNA binding site [nucleotide binding]
568709004362	GlpM protein; Region: GlpM; pfam06942
568709004363	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
568709004364	Spore germination protein; Region: Spore_permease; cl17796
568709004365	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
568709004366	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
568709004367	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
568709004368	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
568709004369	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
568709004370	ligand binding site [chemical binding]; other site
568709004371	homodimer interface [polypeptide binding]; other site
568709004372	NAD(P) binding site [chemical binding]; other site
568709004373	trimer interface B [polypeptide binding]; other site
568709004374	trimer interface A [polypeptide binding]; other site
568709004375	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
568709004376	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
568709004377	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
568709004378	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
568709004379	Domain of unknown function DUF20; Region: UPF0118; pfam01594
568709004380	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
568709004381	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
568709004382	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
568709004383	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
568709004384	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709004385	putative substrate translocation pore; other site
568709004386	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
568709004387	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709004388	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
568709004389	dimerization interface [polypeptide binding]; other site
568709004390	substrate binding pocket [chemical binding]; other site
568709004391	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
568709004392	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
568709004393	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568709004394	putative dithiobiotin synthetase; Provisional; Region: PRK12374
568709004395	AAA domain; Region: AAA_26; pfam13500
568709004396	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
568709004397	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
568709004398	Cl- selectivity filter; other site
568709004399	Cl- binding residues [ion binding]; other site
568709004400	pore gating glutamate residue; other site
568709004401	dimer interface [polypeptide binding]; other site
568709004402	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
568709004403	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
568709004404	Walker A/P-loop; other site
568709004405	ATP binding site [chemical binding]; other site
568709004406	Q-loop/lid; other site
568709004407	ABC transporter signature motif; other site
568709004408	Walker B; other site
568709004409	D-loop; other site
568709004410	H-loop/switch region; other site
568709004411	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
568709004412	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709004413	dimer interface [polypeptide binding]; other site
568709004414	conserved gate region; other site
568709004415	ABC-ATPase subunit interface; other site
568709004416	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
568709004417	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709004418	dimer interface [polypeptide binding]; other site
568709004419	conserved gate region; other site
568709004420	putative PBP binding loops; other site
568709004421	ABC-ATPase subunit interface; other site
568709004422	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
568709004423	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
568709004424	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
568709004425	4Fe-4S binding domain; Region: Fer4; pfam00037
568709004426	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
568709004427	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
568709004428	putative [Fe4-S4] binding site [ion binding]; other site
568709004429	putative molybdopterin cofactor binding site [chemical binding]; other site
568709004430	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
568709004431	putative molybdopterin cofactor binding site; other site
568709004432	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
568709004433	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
568709004434	putative [Fe4-S4] binding site [ion binding]; other site
568709004435	putative molybdopterin cofactor binding site [chemical binding]; other site
568709004436	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
568709004437	putative molybdopterin cofactor binding site; other site
568709004438	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
568709004439	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
568709004440	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
568709004441	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709004442	Coenzyme A binding pocket [chemical binding]; other site
568709004443	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
568709004444	hypothetical protein; Provisional; Region: PRK13659
568709004445	hypothetical protein; Provisional; Region: PRK02237
568709004446	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
568709004447	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
568709004448	putative active site pocket [active]
568709004449	putative metal binding site [ion binding]; other site
568709004450	putative oxidoreductase; Provisional; Region: PRK10083
568709004451	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
568709004452	putative NAD(P) binding site [chemical binding]; other site
568709004453	catalytic Zn binding site [ion binding]; other site
568709004454	structural Zn binding site [ion binding]; other site
568709004455	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709004456	metabolite-proton symporter; Region: 2A0106; TIGR00883
568709004457	putative substrate translocation pore; other site
568709004458	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
568709004459	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
568709004460	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
568709004461	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
568709004462	Transcriptional regulators [Transcription]; Region: GntR; COG1802
568709004463	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709004464	DNA-binding site [nucleotide binding]; DNA binding site
568709004465	FCD domain; Region: FCD; pfam07729
568709004466	malonic semialdehyde reductase; Provisional; Region: PRK10538
568709004467	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
568709004468	putative NAD(P) binding site [chemical binding]; other site
568709004469	homodimer interface [polypeptide binding]; other site
568709004470	homotetramer interface [polypeptide binding]; other site
568709004471	active site
568709004472	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
568709004473	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
568709004474	active site
568709004475	Zn binding site [ion binding]; other site
568709004476	General stress protein [General function prediction only]; Region: GsiB; COG3729
568709004477	hypothetical protein; Validated; Region: PRK03657
568709004478	hypothetical protein; Provisional; Region: PRK10053
568709004479	putative transporter; Provisional; Region: PRK10054
568709004480	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709004481	putative substrate translocation pore; other site
568709004482	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
568709004483	EamA-like transporter family; Region: EamA; pfam00892
568709004484	MarB protein; Region: MarB; pfam13999
568709004485	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
568709004486	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709004487	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709004488	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
568709004489	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
568709004490	inner membrane protein; Provisional; Region: PRK10995
568709004491	putative arabinose transporter; Provisional; Region: PRK03545
568709004492	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709004493	putative substrate translocation pore; other site
568709004494	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709004495	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709004496	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
568709004497	putative dimerization interface [polypeptide binding]; other site
568709004498	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
568709004499	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
568709004500	NAD(P) binding site [chemical binding]; other site
568709004501	catalytic residues [active]
568709004502	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
568709004503	glutaminase; Provisional; Region: PRK00971
568709004504	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
568709004505	Predicted membrane protein [Function unknown]; Region: COG3781
568709004506	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
568709004507	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
568709004508	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
568709004509	eyelet of channel; other site
568709004510	trimer interface [polypeptide binding]; other site
568709004511	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
568709004512	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
568709004513	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
568709004514	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
568709004515	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
568709004516	Rubredoxin [Energy production and conversion]; Region: COG1773
568709004517	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
568709004518	iron binding site [ion binding]; other site
568709004519	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
568709004520	HupF/HypC family; Region: HupF_HypC; cl00394
568709004521	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
568709004522	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
568709004523	putative substrate-binding site; other site
568709004524	nickel binding site [ion binding]; other site
568709004525	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
568709004526	hydrogenase 1 large subunit; Provisional; Region: PRK10170
568709004527	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
568709004528	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
568709004529	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
568709004530	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
568709004531	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
568709004532	active site
568709004533	Transcriptional regulators [Transcription]; Region: FadR; COG2186
568709004534	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709004535	DNA-binding site [nucleotide binding]; DNA binding site
568709004536	FCD domain; Region: FCD; pfam07729
568709004537	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
568709004538	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
568709004539	putative NAD(P) binding site [chemical binding]; other site
568709004540	catalytic Zn binding site [ion binding]; other site
568709004541	structural Zn binding site [ion binding]; other site
568709004542	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709004543	D-galactonate transporter; Region: 2A0114; TIGR00893
568709004544	putative substrate translocation pore; other site
568709004545	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
568709004546	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709004547	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568709004548	putative substrate translocation pore; other site
568709004549	hypothetical protein; Provisional; Region: PRK06184
568709004550	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
568709004551	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
568709004552	Transcriptional regulators [Transcription]; Region: MarR; COG1846
568709004553	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568709004554	putative DNA binding site [nucleotide binding]; other site
568709004555	putative Zn2+ binding site [ion binding]; other site
568709004556	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
568709004557	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
568709004558	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
568709004559	homotrimer interaction site [polypeptide binding]; other site
568709004560	putative active site [active]
568709004561	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
568709004562	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
568709004563	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
568709004566	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
568709004567	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
568709004568	catalytic site [active]
568709004569	active site
568709004570	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
568709004571	acid-resistance protein; Provisional; Region: hdeB; PRK11566
568709004572	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
568709004573	biofilm-dependent modulation protein; Provisional; Region: PRK11436
568709004574	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
568709004575	malate dehydrogenase; Provisional; Region: PRK13529
568709004576	Malic enzyme, N-terminal domain; Region: malic; pfam00390
568709004577	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
568709004578	NAD(P) binding site [chemical binding]; other site
568709004579	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
568709004580	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
568709004581	NAD binding site [chemical binding]; other site
568709004582	substrate binding site [chemical binding]; other site
568709004583	catalytic Zn binding site [ion binding]; other site
568709004584	tetramer interface [polypeptide binding]; other site
568709004585	structural Zn binding site [ion binding]; other site
568709004586	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
568709004587	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
568709004588	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
568709004589	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
568709004590	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
568709004591	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
568709004592	[4Fe-4S] binding site [ion binding]; other site
568709004593	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709004594	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
568709004595	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
568709004596	molybdopterin cofactor binding site; other site
568709004597	aromatic amino acid exporter; Provisional; Region: PRK11689
568709004598	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
568709004599	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
568709004600	trimer interface [polypeptide binding]; other site
568709004601	eyelet of channel; other site
568709004602	Uncharacterized conserved protein [Function unknown]; Region: COG3791
568709004603	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
568709004604	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709004605	putative substrate translocation pore; other site
568709004606	TetR family transcriptional regulator; Provisional; Region: PRK14996
568709004607	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709004608	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
568709004609	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
568709004610	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
568709004611	[4Fe-4S] binding site [ion binding]; other site
568709004612	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709004613	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709004614	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709004615	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
568709004616	molybdopterin cofactor binding site; other site
568709004617	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
568709004618	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
568709004619	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
568709004620	hypothetical protein; Provisional; Region: PRK10281
568709004621	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
568709004622	L-asparagine permease; Provisional; Region: PRK15049
568709004623	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
568709004624	Uncharacterized conserved protein [Function unknown]; Region: COG3391
568709004625	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
568709004626	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
568709004627	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
568709004628	N-terminal plug; other site
568709004629	ligand-binding site [chemical binding]; other site
568709004630	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
568709004631	DNA-binding site [nucleotide binding]; DNA binding site
568709004632	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
568709004633	FCD domain; Region: FCD; pfam07729
568709004634	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
568709004635	Prostaglandin dehydrogenases; Region: PGDH; cd05288
568709004636	NAD(P) binding site [chemical binding]; other site
568709004637	substrate binding site [chemical binding]; other site
568709004638	dimer interface [polypeptide binding]; other site
568709004639	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
568709004640	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
568709004641	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
568709004642	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
568709004643	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
568709004644	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
568709004645	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
568709004646	1-pyrroline dehydrogenase; Region: ABALDH; TIGR03374
568709004647	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
568709004648	tetrameric interface [polypeptide binding]; other site
568709004649	NAD binding site [chemical binding]; other site
568709004650	catalytic residues [active]
568709004651	substrate binding site [chemical binding]; other site
568709004652	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
568709004653	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709004654	DNA-binding site [nucleotide binding]; DNA binding site
568709004655	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709004656	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709004657	homodimer interface [polypeptide binding]; other site
568709004658	catalytic residue [active]
568709004660	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
568709004661	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
568709004662	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
568709004663	Peptidase family U32; Region: Peptidase_U32; pfam01136
568709004664	Collagenase; Region: DUF3656; pfam12392
568709004665	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568709004666	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709004667	non-specific DNA binding site [nucleotide binding]; other site
568709004668	salt bridge; other site
568709004669	sequence-specific DNA binding site [nucleotide binding]; other site
568709004670	Cupin domain; Region: Cupin_2; pfam07883
568709004671	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
568709004672	benzoate transporter; Region: benE; TIGR00843
568709004673	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
568709004674	tellurite resistance protein TehB; Provisional; Region: PRK11207
568709004675	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709004676	S-adenosylmethionine binding site [chemical binding]; other site
568709004677	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
568709004678	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
568709004679	gating phenylalanine in ion channel; other site
568709004680	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
568709004681	putative trimer interface [polypeptide binding]; other site
568709004682	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
568709004683	putative trimer interface [polypeptide binding]; other site
568709004684	putative CoA binding site [chemical binding]; other site
568709004685	putative CoA binding site [chemical binding]; other site
568709004686	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
568709004687	putative trimer interface [polypeptide binding]; other site
568709004688	putative CoA binding site [chemical binding]; other site
568709004689	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
568709004690	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709004691	Coenzyme A binding pocket [chemical binding]; other site
568709004692	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
568709004693	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
568709004694	oligomer interface [polypeptide binding]; other site
568709004695	active site
568709004696	metal binding site [ion binding]; metal-binding site
568709004697	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
568709004698	active site
568709004699	P-loop; other site
568709004700	phosphorylation site [posttranslational modification]
568709004701	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
568709004702	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
568709004703	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
568709004704	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709004705	active site
568709004706	phosphorylation site [posttranslational modification]
568709004707	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
568709004708	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
568709004709	substrate binding site [chemical binding]; other site
568709004710	hexamer interface [polypeptide binding]; other site
568709004711	metal binding site [ion binding]; metal-binding site
568709004712	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568709004713	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
568709004714	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709004715	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
568709004716	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709004717	Coenzyme A binding pocket [chemical binding]; other site
568709004718	L-lactate oxidase; Region: L_lactate_ox; TIGR02708
568709004719	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
568709004720	teramer interface [polypeptide binding]; other site
568709004721	active site
568709004722	FMN binding site [chemical binding]; other site
568709004723	catalytic residues [active]
568709004724	Uncharacterized conserved protein [Function unknown]; Region: COG2353
568709004725	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
568709004726	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
568709004727	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
568709004728	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
568709004729	substrate binding pocket [chemical binding]; other site
568709004730	catalytic triad [active]
568709004731	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
568709004732	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
568709004733	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
568709004734	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709004735	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709004736	dimerization interface [polypeptide binding]; other site
568709004737	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
568709004738	dimer interface [polypeptide binding]; other site
568709004739	ligand binding site [chemical binding]; other site
568709004740	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
568709004741	HAMP domain; Region: HAMP; pfam00672
568709004742	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
568709004743	dimer interface [polypeptide binding]; other site
568709004744	putative CheW interface [polypeptide binding]; other site
568709004745	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
568709004746	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
568709004747	substrate binding site [chemical binding]; other site
568709004748	catalytic Zn binding site [ion binding]; other site
568709004749	NAD binding site [chemical binding]; other site
568709004750	structural Zn binding site [ion binding]; other site
568709004751	dimer interface [polypeptide binding]; other site
568709004752	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
568709004753	putative metal binding site [ion binding]; other site
568709004754	putative homodimer interface [polypeptide binding]; other site
568709004755	putative homotetramer interface [polypeptide binding]; other site
568709004756	putative homodimer-homodimer interface [polypeptide binding]; other site
568709004757	putative allosteric switch controlling residues; other site
568709004758	Sif protein; Region: Sif; cl11505
568709004759	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
568709004760	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
568709004761	active site
568709004762	catalytic triad [active]
568709004763	oxyanion hole [active]
568709004764	Predicted membrane protein [Function unknown]; Region: COG3326
568709004765	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709004766	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
568709004767	substrate binding pocket [chemical binding]; other site
568709004768	membrane-bound complex binding site; other site
568709004769	hinge residues; other site
568709004770	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568709004771	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709004772	dimer interface [polypeptide binding]; other site
568709004773	conserved gate region; other site
568709004774	putative PBP binding loops; other site
568709004775	ABC-ATPase subunit interface; other site
568709004776	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
568709004777	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709004778	Walker A/P-loop; other site
568709004779	ATP binding site [chemical binding]; other site
568709004780	Q-loop/lid; other site
568709004781	ABC transporter signature motif; other site
568709004782	Walker B; other site
568709004783	D-loop; other site
568709004784	H-loop/switch region; other site
568709004785	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568709004786	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709004787	dimer interface [polypeptide binding]; other site
568709004788	conserved gate region; other site
568709004789	putative PBP binding loops; other site
568709004790	ABC-ATPase subunit interface; other site
568709004791	Predicted membrane protein [Function unknown]; Region: COG5305
568709004792	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
568709004793	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709004794	S-adenosylmethionine binding site [chemical binding]; other site
568709004795	cytochrome b561; Provisional; Region: PRK11513
568709004796	Uncharacterized conserved protein [Function unknown]; Region: COG1434
568709004797	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
568709004798	putative active site [active]
568709004799	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
568709004800	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568709004801	ATP binding site [chemical binding]; other site
568709004802	putative Mg++ binding site [ion binding]; other site
568709004803	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709004804	nucleotide binding region [chemical binding]; other site
568709004805	ATP-binding site [chemical binding]; other site
568709004806	Helicase associated domain (HA2); Region: HA2; pfam04408
568709004807	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
568709004808	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
568709004809	azoreductase; Reviewed; Region: PRK00170
568709004810	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
568709004811	Uncharacterized conserved protein [Function unknown]; Region: COG3791
568709004812	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
568709004813	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
568709004814	hypothetical protein; Provisional; Region: PRK10695
568709004815	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
568709004816	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
568709004817	putative ligand binding site [chemical binding]; other site
568709004818	putative NAD binding site [chemical binding]; other site
568709004819	catalytic site [active]
568709004820	heat-inducible protein; Provisional; Region: PRK10449
568709004821	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
568709004822	Domain of unknown function (DUF333); Region: DUF333; pfam03891
568709004823	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
568709004824	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
568709004825	dimer interface [polypeptide binding]; other site
568709004826	PYR/PP interface [polypeptide binding]; other site
568709004827	TPP binding site [chemical binding]; other site
568709004828	substrate binding site [chemical binding]; other site
568709004829	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
568709004830	Domain of unknown function; Region: EKR; smart00890
568709004831	4Fe-4S binding domain; Region: Fer4_6; pfam12837
568709004832	4Fe-4S binding domain; Region: Fer4; pfam00037
568709004833	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
568709004834	TPP-binding site [chemical binding]; other site
568709004835	dimer interface [polypeptide binding]; other site
568709004836	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
568709004837	Ligand Binding Site [chemical binding]; other site
568709004838	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
568709004839	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
568709004840	DNA binding site [nucleotide binding]
568709004841	active site
568709004842	Int/Topo IB signature motif; other site
568709004843	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
568709004844	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
568709004845	Ligand Binding Site [chemical binding]; other site
568709004846	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
568709004847	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
568709004848	ATP binding site [chemical binding]; other site
568709004849	Mg++ binding site [ion binding]; other site
568709004850	motif III; other site
568709004851	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709004852	nucleotide binding region [chemical binding]; other site
568709004853	ATP-binding site [chemical binding]; other site
568709004854	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
568709004855	putative RNA binding site [nucleotide binding]; other site
568709004856	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
568709004857	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
568709004858	Cl binding site [ion binding]; other site
568709004859	oligomer interface [polypeptide binding]; other site
568709004860	HAMP domain; Region: HAMP; pfam00672
568709004861	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
568709004862	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
568709004863	dimer interface [polypeptide binding]; other site
568709004864	putative CheW interface [polypeptide binding]; other site
568709004865	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
568709004866	Smr domain; Region: Smr; pfam01713
568709004867	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
568709004868	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
568709004869	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
568709004870	DNA binding site [nucleotide binding]
568709004871	active site
568709004872	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
568709004873	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
568709004874	ligand binding site [chemical binding]; other site
568709004875	flexible hinge region; other site
568709004876	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
568709004877	putative switch regulator; other site
568709004878	non-specific DNA interactions [nucleotide binding]; other site
568709004879	DNA binding site [nucleotide binding]
568709004880	sequence specific DNA binding site [nucleotide binding]; other site
568709004881	putative cAMP binding site [chemical binding]; other site
568709004882	universal stress protein UspE; Provisional; Region: PRK11175
568709004883	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
568709004884	Ligand Binding Site [chemical binding]; other site
568709004885	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
568709004886	Ligand Binding Site [chemical binding]; other site
568709004887	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
568709004888	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
568709004889	Mechanosensitive ion channel; Region: MS_channel; pfam00924
568709004890	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
568709004891	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709004892	non-specific DNA binding site [nucleotide binding]; other site
568709004893	salt bridge; other site
568709004894	sequence-specific DNA binding site [nucleotide binding]; other site
568709004895	Cupin domain; Region: Cupin_2; pfam07883
568709004896	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
568709004897	B3/4 domain; Region: B3_4; pfam03483
568709004898	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: Tpx; COG2077
568709004899	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
568709004900	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568709004901	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709004902	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
568709004903	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
568709004904	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
568709004905	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709004906	oxidoreductase; Provisional; Region: PRK12742
568709004907	classical (c) SDRs; Region: SDR_c; cd05233
568709004908	NAD(P) binding site [chemical binding]; other site
568709004909	active site
568709004910	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568709004911	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568709004912	active site
568709004913	catalytic tetrad [active]
568709004914	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709004915	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709004916	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
568709004917	putative effector binding pocket; other site
568709004918	putative dimerization interface [polypeptide binding]; other site
568709004919	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
568709004920	NmrA-like family; Region: NmrA; pfam05368
568709004921	NAD(P) binding site [chemical binding]; other site
568709004922	active site lysine
568709004923	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
568709004924	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
568709004925	peptide binding site [polypeptide binding]; other site
568709004926	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
568709004927	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
568709004928	putative active site [active]
568709004929	Zn binding site [ion binding]; other site
568709004930	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
568709004931	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
568709004932	active site
568709004933	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
568709004934	dimer interface [polypeptide binding]; other site
568709004935	catalytic triad [active]
568709004936	peroxidatic and resolving cysteines [active]
568709004937	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
568709004938	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
568709004939	putative aromatic amino acid binding site; other site
568709004940	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709004941	Walker A motif; other site
568709004942	ATP binding site [chemical binding]; other site
568709004943	Walker B motif; other site
568709004944	arginine finger; other site
568709004945	hypothetical protein; Provisional; Region: PRK05415
568709004946	TIGR01620 family protein; Region: hyp_HI0043
568709004947	Predicted ATPase [General function prediction only]; Region: COG3106
568709004948	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
568709004949	active site residue [active]
568709004950	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
568709004951	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
568709004952	phage shock protein C; Region: phageshock_pspC; TIGR02978
568709004953	phage shock protein B; Provisional; Region: pspB; PRK09458
568709004954	phage shock protein PspA; Provisional; Region: PRK10698
568709004955	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
568709004956	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709004957	Walker A motif; other site
568709004958	ATP binding site [chemical binding]; other site
568709004959	Walker B motif; other site
568709004960	arginine finger; other site
568709004961	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
568709004962	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
568709004963	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
568709004964	peptide binding site [polypeptide binding]; other site
568709004965	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
568709004966	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709004967	dimer interface [polypeptide binding]; other site
568709004968	conserved gate region; other site
568709004969	putative PBP binding loops; other site
568709004970	ABC-ATPase subunit interface; other site
568709004971	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
568709004972	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
568709004973	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709004974	dimer interface [polypeptide binding]; other site
568709004975	conserved gate region; other site
568709004976	putative PBP binding loops; other site
568709004977	ABC-ATPase subunit interface; other site
568709004978	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
568709004979	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709004980	Walker A/P-loop; other site
568709004981	ATP binding site [chemical binding]; other site
568709004982	Q-loop/lid; other site
568709004983	ABC transporter signature motif; other site
568709004984	Walker B; other site
568709004985	D-loop; other site
568709004986	H-loop/switch region; other site
568709004987	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
568709004988	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
568709004989	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709004990	Walker A/P-loop; other site
568709004991	ATP binding site [chemical binding]; other site
568709004992	Q-loop/lid; other site
568709004993	ABC transporter signature motif; other site
568709004994	Walker B; other site
568709004995	D-loop; other site
568709004996	H-loop/switch region; other site
568709004997	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
568709004998	Protein kinase domain; Region: Pkinase; pfam00069
568709004999	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
568709005000	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
568709005001	NAD binding site [chemical binding]; other site
568709005002	homotetramer interface [polypeptide binding]; other site
568709005003	homodimer interface [polypeptide binding]; other site
568709005004	substrate binding site [chemical binding]; other site
568709005005	active site
568709005006	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
568709005007	Uncharacterized conserved protein [Function unknown]; Region: COG2128
568709005008	exoribonuclease II; Provisional; Region: PRK05054
568709005009	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
568709005010	RNB domain; Region: RNB; pfam00773
568709005011	S1 RNA binding domain; Region: S1; pfam00575
568709005012	RNase II stability modulator; Provisional; Region: PRK10060
568709005013	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
568709005014	putative active site [active]
568709005015	heme pocket [chemical binding]; other site
568709005016	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568709005017	metal binding site [ion binding]; metal-binding site
568709005018	active site
568709005019	I-site; other site
568709005020	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709005021	hypothetical protein; Provisional; Region: PRK13658
568709005022	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568709005023	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
568709005024	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709005025	lipoprotein; Provisional; Region: PRK10540
568709005026	translation initiation factor Sui1; Validated; Region: PRK06824
568709005027	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
568709005028	putative rRNA binding site [nucleotide binding]; other site
568709005029	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
568709005030	active site
568709005031	dimer interface [polypeptide binding]; other site
568709005032	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
568709005033	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
568709005034	TPR motif; other site
568709005035	binding surface
568709005036	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
568709005037	binding surface
568709005038	TPR motif; other site
568709005039	Predicted membrane protein [Function unknown]; Region: COG3771
568709005040	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
568709005041	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
568709005042	active site
568709005043	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
568709005044	dimerization interface [polypeptide binding]; other site
568709005045	active site
568709005046	aconitate hydratase; Validated; Region: PRK09277
568709005047	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
568709005048	substrate binding site [chemical binding]; other site
568709005049	ligand binding site [chemical binding]; other site
568709005050	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
568709005051	substrate binding site [chemical binding]; other site
568709005052	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
568709005053	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709005054	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
568709005055	substrate binding site [chemical binding]; other site
568709005056	putative dimerization interface [polypeptide binding]; other site
568709005057	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
568709005058	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
568709005059	active site
568709005060	interdomain interaction site; other site
568709005061	putative metal-binding site [ion binding]; other site
568709005062	nucleotide binding site [chemical binding]; other site
568709005063	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
568709005064	domain I; other site
568709005065	DNA binding groove [nucleotide binding]
568709005066	phosphate binding site [ion binding]; other site
568709005067	domain II; other site
568709005068	domain III; other site
568709005069	nucleotide binding site [chemical binding]; other site
568709005070	catalytic site [active]
568709005071	domain IV; other site
568709005072	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
568709005073	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
568709005074	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
568709005075	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
568709005076	hypothetical protein; Provisional; Region: PRK11037
568709005077	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
568709005078	putative inner membrane peptidase; Provisional; Region: PRK11778
568709005079	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
568709005080	tandem repeat interface [polypeptide binding]; other site
568709005081	oligomer interface [polypeptide binding]; other site
568709005082	active site residues [active]
568709005083	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
568709005084	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
568709005085	NADP binding site [chemical binding]; other site
568709005086	homodimer interface [polypeptide binding]; other site
568709005087	active site
568709005088	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
568709005089	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
568709005090	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
568709005091	homodimer interface [polypeptide binding]; other site
568709005092	Walker A motif; other site
568709005093	ATP binding site [chemical binding]; other site
568709005094	hydroxycobalamin binding site [chemical binding]; other site
568709005095	Walker B motif; other site
568709005096	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
568709005097	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568709005098	RNA binding surface [nucleotide binding]; other site
568709005099	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
568709005100	probable active site [active]
568709005101	hypothetical protein; Provisional; Region: PRK11630
568709005102	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
568709005103	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
568709005104	active site
568709005105	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
568709005106	anthranilate synthase component I; Provisional; Region: PRK13564
568709005107	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
568709005108	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
568709005109	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
568709005110	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
568709005111	glutamine binding [chemical binding]; other site
568709005112	catalytic triad [active]
568709005113	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
568709005114	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
568709005115	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
568709005116	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
568709005117	active site
568709005118	ribulose/triose binding site [chemical binding]; other site
568709005119	phosphate binding site [ion binding]; other site
568709005120	substrate (anthranilate) binding pocket [chemical binding]; other site
568709005121	product (indole) binding pocket [chemical binding]; other site
568709005122	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
568709005123	active site
568709005124	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
568709005125	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
568709005126	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709005127	catalytic residue [active]
568709005128	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
568709005129	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
568709005130	substrate binding site [chemical binding]; other site
568709005131	active site
568709005132	catalytic residues [active]
568709005133	heterodimer interface [polypeptide binding]; other site
568709005134	General stress protein [General function prediction only]; Region: GsiB; COG3729
568709005135	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
568709005136	dimerization interface [polypeptide binding]; other site
568709005137	metal binding site [ion binding]; metal-binding site
568709005138	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
568709005139	dinuclear metal binding motif [ion binding]; other site
568709005140	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
568709005141	dimanganese center [ion binding]; other site
568709005142	outer membrane protein W; Provisional; Region: PRK10959
568709005143	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
568709005144	hypothetical protein; Provisional; Region: PRK02868
568709005145	intracellular septation protein A; Reviewed; Region: PRK00259
568709005146	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
568709005147	transport protein TonB; Provisional; Region: PRK10819
568709005148	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
568709005149	YciI-like protein; Reviewed; Region: PRK11370
568709005150	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
568709005151	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
568709005152	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
568709005153	putative active site [active]
568709005154	catalytic site [active]
568709005155	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
568709005156	putative active site [active]
568709005157	catalytic site [active]
568709005158	dsDNA-mimic protein; Reviewed; Region: PRK05094
568709005159	Ion transport protein; Region: Ion_trans; pfam00520
568709005160	Ion channel; Region: Ion_trans_2; pfam07885
568709005161	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
568709005162	Double zinc ribbon; Region: DZR; pfam12773
568709005163	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
568709005164	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709005165	Walker A/P-loop; other site
568709005166	ATP binding site [chemical binding]; other site
568709005167	Q-loop/lid; other site
568709005168	ABC transporter signature motif; other site
568709005169	Walker B; other site
568709005170	D-loop; other site
568709005171	H-loop/switch region; other site
568709005172	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
568709005173	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
568709005174	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709005175	Walker A/P-loop; other site
568709005176	ATP binding site [chemical binding]; other site
568709005177	Q-loop/lid; other site
568709005178	ABC transporter signature motif; other site
568709005179	Walker B; other site
568709005180	D-loop; other site
568709005181	H-loop/switch region; other site
568709005182	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
568709005183	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
568709005184	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
568709005185	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709005186	dimer interface [polypeptide binding]; other site
568709005187	conserved gate region; other site
568709005188	ABC-ATPase subunit interface; other site
568709005189	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
568709005190	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709005191	dimer interface [polypeptide binding]; other site
568709005192	conserved gate region; other site
568709005193	putative PBP binding loops; other site
568709005194	ABC-ATPase subunit interface; other site
568709005195	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
568709005196	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
568709005197	peptide binding site [polypeptide binding]; other site
568709005198	hypothetical protein; Provisional; Region: PRK11111
568709005199	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
568709005200	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
568709005201	putative catalytic cysteine [active]
568709005202	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
568709005203	putative active site [active]
568709005204	metal binding site [ion binding]; metal-binding site
568709005205	thymidine kinase; Provisional; Region: PRK04296
568709005206	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
568709005207	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
568709005208	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
568709005209	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
568709005210	active site
568709005211	tetramer interface; other site
568709005212	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709005213	active site
568709005214	response regulator of RpoS; Provisional; Region: PRK10693
568709005215	phosphorylation site [posttranslational modification]
568709005216	intermolecular recognition site; other site
568709005217	dimerization interface [polypeptide binding]; other site
568709005218	hypothetical protein; Provisional; Region: PRK10279
568709005219	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
568709005220	active site
568709005221	nucleophile elbow; other site
568709005222	SEC-C motif; Region: SEC-C; pfam02810
568709005223	hypothetical protein; Provisional; Region: PRK04233
568709005224	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
568709005225	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
568709005226	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
568709005227	putative active site [active]
568709005228	putative substrate binding site [chemical binding]; other site
568709005229	putative cosubstrate binding site; other site
568709005230	catalytic site [active]
568709005231	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
568709005232	Sel1-like repeats; Region: SEL1; smart00671
568709005233	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
568709005234	Sel1-like repeats; Region: SEL1; smart00671
568709005235	Sel1-like repeats; Region: SEL1; smart00671
568709005236	Sel1-like repeats; Region: SEL1; smart00671
568709005237	Sel1-like repeats; Region: SEL1; smart00671
568709005238	Sel1-like repeats; Region: SEL1; smart00671
568709005239	Sel1-like repeats; Region: SEL1; smart00671
568709005240	Sel1-like repeats; Region: SEL1; smart00671
568709005241	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
568709005242	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
568709005243	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
568709005244	4Fe-4S binding domain; Region: Fer4; cl02805
568709005245	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
568709005246	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
568709005247	[4Fe-4S] binding site [ion binding]; other site
568709005248	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709005249	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709005250	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709005251	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
568709005252	molybdopterin cofactor binding site; other site
568709005253	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
568709005254	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
568709005255	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
568709005256	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709005257	dimerization interface [polypeptide binding]; other site
568709005258	Histidine kinase; Region: HisKA_3; pfam07730
568709005259	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709005260	ATP binding site [chemical binding]; other site
568709005261	Mg2+ binding site [ion binding]; other site
568709005262	G-X-G motif; other site
568709005263	putative invasin; Provisional; Region: PRK10177
568709005264	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
568709005265	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
568709005266	cation transport regulator; Reviewed; Region: chaB; PRK09582
568709005267	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
568709005268	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
568709005269	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
568709005270	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
568709005271	hypothetical protein; Provisional; Region: PRK10941
568709005272	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
568709005273	hypothetical protein; Provisional; Region: PRK10278
568709005274	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
568709005275	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709005276	peptide chain release factor 1; Validated; Region: prfA; PRK00591
568709005277	This domain is found in peptide chain release factors; Region: PCRF; smart00937
568709005278	RF-1 domain; Region: RF-1; pfam00472
568709005279	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
568709005280	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
568709005281	tRNA; other site
568709005282	putative tRNA binding site [nucleotide binding]; other site
568709005283	putative NADP binding site [chemical binding]; other site
568709005284	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
568709005285	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
568709005286	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
568709005287	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
568709005288	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
568709005289	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
568709005290	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
568709005291	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568709005292	active site
568709005293	putative transporter; Provisional; Region: PRK11660
568709005294	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
568709005295	Sulfate transporter family; Region: Sulfate_transp; pfam00916
568709005296	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
568709005297	hypothetical protein; Provisional; Region: PRK10692
568709005298	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
568709005299	putative active site [active]
568709005300	catalytic residue [active]
568709005301	GTP-binding protein YchF; Reviewed; Region: PRK09601
568709005302	YchF GTPase; Region: YchF; cd01900
568709005303	G1 box; other site
568709005304	GTP/Mg2+ binding site [chemical binding]; other site
568709005305	Switch I region; other site
568709005306	G2 box; other site
568709005307	Switch II region; other site
568709005308	G3 box; other site
568709005309	G4 box; other site
568709005310	G5 box; other site
568709005311	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
568709005312	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
568709005313	Protein of unknown function (DUF4427); Region: DUF4427; pfam14468
568709005314	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
568709005315	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
568709005316	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
568709005317	hydrogenase 1 large subunit; Provisional; Region: PRK10170
568709005318	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
568709005319	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
568709005320	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
568709005321	putative substrate-binding site; other site
568709005322	nickel binding site [ion binding]; other site
568709005323	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
568709005324	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
568709005325	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
568709005326	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
568709005327	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
568709005328	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
568709005329	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
568709005330	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
568709005331	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
568709005332	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
568709005333	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
568709005334	NAD(P) binding site [chemical binding]; other site
568709005335	trehalase; Provisional; Region: treA; PRK13271
568709005336	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
568709005337	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
568709005338	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
568709005339	Flagellar regulator YcgR; Region: YcgR; pfam07317
568709005340	PilZ domain; Region: PilZ; pfam07238
568709005341	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
568709005342	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
568709005343	N-acetyl-D-glucosamine binding site [chemical binding]; other site
568709005344	catalytic residue [active]
568709005345	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
568709005346	dimer interface [polypeptide binding]; other site
568709005347	catalytic triad [active]
568709005348	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
568709005349	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
568709005350	TrkA-C domain; Region: TrkA_C; pfam02080
568709005351	Transporter associated domain; Region: CorC_HlyC; smart01091
568709005352	alanine racemase; Reviewed; Region: dadX; PRK03646
568709005353	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
568709005354	active site
568709005355	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
568709005356	substrate binding site [chemical binding]; other site
568709005357	catalytic residues [active]
568709005358	dimer interface [polypeptide binding]; other site
568709005359	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
568709005360	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
568709005361	SpoVR family protein; Provisional; Region: PRK11767
568709005362	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
568709005363	fatty acid metabolism regulator; Provisional; Region: PRK04984
568709005364	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709005365	DNA-binding site [nucleotide binding]; DNA binding site
568709005366	FadR C-terminal domain; Region: FadR_C; pfam07840
568709005367	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
568709005368	transmembrane helices; other site
568709005369	disulfide bond formation protein B; Provisional; Region: PRK01749
568709005370	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
568709005371	GnsA/GnsB family; Region: GnsAB; pfam08178
568709005372	hypothetical protein; Provisional; Region: PRK05170
568709005373	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
568709005374	hypothetical protein; Provisional; Region: PRK10691
568709005375	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
568709005376	septum formation inhibitor; Reviewed; Region: minC; PRK03511
568709005377	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
568709005378	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
568709005379	cell division inhibitor MinD; Provisional; Region: PRK10818
568709005380	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
568709005381	Switch I; other site
568709005382	Switch II; other site
568709005383	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
568709005384	ribonuclease D; Provisional; Region: PRK10829
568709005385	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
568709005386	catalytic site [active]
568709005387	putative active site [active]
568709005388	putative substrate binding site [chemical binding]; other site
568709005389	HRDC domain; Region: HRDC; cl02578
568709005390	Transposase IS200 like; Region: Y1_Tnp; pfam01797
568709005391	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
568709005392	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
568709005393	acyl-activating enzyme (AAE) consensus motif; other site
568709005394	putative AMP binding site [chemical binding]; other site
568709005395	putative active site [active]
568709005396	putative CoA binding site [chemical binding]; other site
568709005398	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
568709005399	Glycoprotease family; Region: Peptidase_M22; pfam00814
568709005400	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
568709005401	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
568709005402	DEAD_2; Region: DEAD_2; pfam06733
568709005403	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
568709005404	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
568709005405	homotrimer interaction site [polypeptide binding]; other site
568709005406	putative active site [active]
568709005407	hypothetical protein; Provisional; Region: PRK05114
568709005408	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
568709005409	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
568709005410	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
568709005411	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
568709005412	putative active site [active]
568709005413	putative CoA binding site [chemical binding]; other site
568709005414	nudix motif; other site
568709005415	metal binding site [ion binding]; metal-binding site
568709005416	L-serine deaminase; Provisional; Region: PRK15023
568709005417	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
568709005418	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
568709005419	phage resistance protein; Provisional; Region: PRK10551
568709005420	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
568709005421	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709005422	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
568709005423	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
568709005424	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
568709005425	Transporter associated domain; Region: CorC_HlyC; smart01091
568709005426	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
568709005427	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
568709005428	active pocket/dimerization site; other site
568709005429	active site
568709005430	phosphorylation site [posttranslational modification]
568709005431	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
568709005432	active site
568709005433	phosphorylation site [posttranslational modification]
568709005434	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
568709005435	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
568709005436	hypothetical protein; Provisional; Region: PRK02913
568709005437	hypothetical protein; Provisional; Region: PRK11469
568709005438	Domain of unknown function DUF; Region: DUF204; pfam02659
568709005439	Domain of unknown function DUF; Region: DUF204; pfam02659
568709005440	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
568709005441	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709005442	S-adenosylmethionine binding site [chemical binding]; other site
568709005443	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
568709005444	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
568709005445	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
568709005446	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
568709005447	DNA-binding site [nucleotide binding]; DNA binding site
568709005448	RNA-binding motif; other site
568709005449	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
568709005450	YebO-like protein; Region: YebO; pfam13974
568709005451	PhoPQ regulatory protein; Provisional; Region: PRK10299
568709005452	YobH-like protein; Region: YobH; pfam13996
568709005453	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
568709005454	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568709005455	dimerization interface [polypeptide binding]; other site
568709005456	putative Zn2+ binding site [ion binding]; other site
568709005457	putative DNA binding site [nucleotide binding]; other site
568709005458	Bacterial transcriptional regulator; Region: IclR; pfam01614
568709005459	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709005460	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568709005461	putative substrate translocation pore; other site
568709005462	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709005463	heat shock protein HtpX; Provisional; Region: PRK05457
568709005464	carboxy-terminal protease; Provisional; Region: PRK11186
568709005465	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
568709005466	protein binding site [polypeptide binding]; other site
568709005467	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
568709005468	Catalytic dyad [active]
568709005469	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
568709005470	ProP expression regulator; Provisional; Region: PRK04950
568709005471	ProQ/FINO family; Region: ProQ; pfam04352
568709005472	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
568709005473	GAF domain; Region: GAF_2; pfam13185
568709005474	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
568709005475	Paraquat-inducible protein A; Region: PqiA; pfam04403
568709005476	Paraquat-inducible protein A; Region: PqiA; pfam04403
568709005477	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
568709005478	mce related protein; Region: MCE; pfam02470
568709005479	mce related protein; Region: MCE; pfam02470
568709005480	mce related protein; Region: MCE; pfam02470
568709005481	mce related protein; Region: MCE; pfam02470
568709005482	mce related protein; Region: MCE; pfam02470
568709005483	mce related protein; Region: MCE; pfam02470
568709005484	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
568709005485	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
568709005486	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
568709005487	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
568709005488	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
568709005489	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
568709005490	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
568709005491	type III secretion protein SopE2; Provisional; Region: PRK15280
568709005492	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
568709005493	SopE GEF domain; Region: SopE_GEF; pfam07487
568709005494	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
568709005495	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709005496	Coenzyme A binding pocket [chemical binding]; other site
568709005499	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
568709005500	DNA binding site [nucleotide binding]
568709005501	active site
568709005502	Int/Topo IB signature motif; other site
568709005503	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
568709005504	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
568709005505	EamA-like transporter family; Region: EamA; pfam00892
568709005506	EamA-like transporter family; Region: EamA; pfam00892
568709005507	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
568709005508	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
568709005509	DNA-binding interface [nucleotide binding]; DNA binding site
568709005510	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
568709005511	ADP-ribose binding site [chemical binding]; other site
568709005512	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
568709005513	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
568709005514	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
568709005515	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
568709005516	exonuclease VIII; Reviewed; Region: PRK09709
568709005517	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
568709005518	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
568709005519	dimer interface [polypeptide binding]; other site
568709005520	active site
568709005521	Int/Topo IB signature motif; other site
568709005522	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
568709005523	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
568709005524	hypothetical protein; Provisional; Region: PRK10301
568709005525	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
568709005526	Predicted amidohydrolase [General function prediction only]; Region: COG0388
568709005527	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
568709005528	exodeoxyribonuclease X; Provisional; Region: PRK07983
568709005529	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
568709005530	active site
568709005531	catalytic site [active]
568709005532	substrate binding site [chemical binding]; other site
568709005533	protease 2; Provisional; Region: PRK10115
568709005534	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
568709005535	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
568709005536	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
568709005537	putative metal binding site [ion binding]; other site
568709005538	hypothetical protein; Provisional; Region: PRK13680
568709005539	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
568709005540	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
568709005541	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
568709005542	ATP-grasp domain; Region: ATP-grasp; pfam02222
568709005543	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
568709005544	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
568709005545	active site
568709005546	intersubunit interface [polypeptide binding]; other site
568709005547	catalytic residue [active]
568709005548	phosphogluconate dehydratase; Validated; Region: PRK09054
568709005549	6-phosphogluconate dehydratase; Region: edd; TIGR01196
568709005550	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
568709005551	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
568709005552	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
568709005553	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
568709005554	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568709005555	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568709005556	putative active site [active]
568709005557	pyruvate kinase; Provisional; Region: PRK05826
568709005558	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
568709005559	domain interfaces; other site
568709005560	active site
568709005561	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
568709005562	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
568709005563	putative acyl-acceptor binding pocket; other site
568709005564	putative peptidase; Provisional; Region: PRK11649
568709005565	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
568709005566	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568709005567	Peptidase family M23; Region: Peptidase_M23; pfam01551
568709005568	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
568709005569	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
568709005570	metal binding site [ion binding]; metal-binding site
568709005571	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
568709005572	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
568709005573	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
568709005574	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
568709005575	ABC-ATPase subunit  interface; other site
568709005576	dimer interface [polypeptide binding]; other site
568709005577	putative PBP binding regions; other site
568709005578	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
568709005579	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709005580	Walker A motif; other site
568709005581	ATP binding site [chemical binding]; other site
568709005582	Walker B motif; other site
568709005583	arginine finger; other site
568709005584	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
568709005585	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
568709005586	RuvA N terminal domain; Region: RuvA_N; pfam01330
568709005587	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
568709005588	contains a frameshift after residue 80
568709005589	contains two frameshifts after residues 55 and 104
568709005590	hypothetical protein; Provisional; Region: PRK11470
568709005591	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
568709005592	active site
568709005593	putative DNA-binding cleft [nucleotide binding]; other site
568709005594	dimer interface [polypeptide binding]; other site
568709005595	hypothetical protein; Validated; Region: PRK00110
568709005596	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
568709005597	nudix motif; other site
568709005598	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
568709005599	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
568709005600	dimer interface [polypeptide binding]; other site
568709005601	anticodon binding site; other site
568709005602	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
568709005603	homodimer interface [polypeptide binding]; other site
568709005604	motif 1; other site
568709005605	active site
568709005606	motif 2; other site
568709005607	GAD domain; Region: GAD; pfam02938
568709005608	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
568709005609	active site
568709005610	motif 3; other site
568709005611	Isochorismatase family; Region: Isochorismatase; pfam00857
568709005612	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
568709005613	catalytic triad [active]
568709005614	conserved cis-peptide bond; other site
568709005615	hypothetical protein; Provisional; Region: PRK10302
568709005616	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
568709005617	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709005618	S-adenosylmethionine binding site [chemical binding]; other site
568709005619	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709005620	S-adenosylmethionine binding site [chemical binding]; other site
568709005621	copper homeostasis protein CutC; Provisional; Region: PRK11572
568709005622	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
568709005623	putative metal binding site [ion binding]; other site
568709005624	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
568709005625	arginyl-tRNA synthetase; Region: argS; TIGR00456
568709005626	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
568709005627	active site
568709005628	HIGH motif; other site
568709005629	KMSK motif region; other site
568709005630	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
568709005631	tRNA binding surface [nucleotide binding]; other site
568709005632	anticodon binding site; other site
568709005633	penicillin-binding protein 2; Provisional; Region: PRK10795
568709005634	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
568709005635	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
568709005636	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
568709005637	Flagellar protein FlhE; Region: FlhE; pfam06366
568709005638	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
568709005639	FHIPEP family; Region: FHIPEP; pfam00771
568709005640	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
568709005641	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
568709005642	chemotaxis regulator CheZ; Provisional; Region: PRK11166
568709005643	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
568709005644	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709005645	active site
568709005646	phosphorylation site [posttranslational modification]
568709005647	intermolecular recognition site; other site
568709005648	dimerization interface [polypeptide binding]; other site
568709005649	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
568709005650	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709005651	active site
568709005652	phosphorylation site [posttranslational modification]
568709005653	intermolecular recognition site; other site
568709005654	dimerization interface [polypeptide binding]; other site
568709005655	CheB methylesterase; Region: CheB_methylest; pfam01339
568709005656	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
568709005657	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
568709005658	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709005659	S-adenosylmethionine binding site [chemical binding]; other site
568709005660	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
568709005661	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
568709005662	dimer interface [polypeptide binding]; other site
568709005663	ligand binding site [chemical binding]; other site
568709005664	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709005665	dimerization interface [polypeptide binding]; other site
568709005666	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
568709005667	dimer interface [polypeptide binding]; other site
568709005668	putative CheW interface [polypeptide binding]; other site
568709005669	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
568709005670	putative CheA interaction surface; other site
568709005671	chemotaxis protein CheA; Provisional; Region: PRK10547
568709005672	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
568709005673	putative binding surface; other site
568709005674	active site
568709005675	CheY binding; Region: CheY-binding; pfam09078
568709005676	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
568709005677	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709005678	ATP binding site [chemical binding]; other site
568709005679	Mg2+ binding site [ion binding]; other site
568709005680	G-X-G motif; other site
568709005681	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
568709005682	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
568709005683	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
568709005684	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
568709005685	ligand binding site [chemical binding]; other site
568709005686	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
568709005687	flagellar motor protein MotA; Validated; Region: PRK09110
568709005688	transcriptional activator FlhC; Provisional; Region: PRK12722
568709005689	transcriptional activator FlhD; Provisional; Region: PRK02909
568709005690	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
568709005691	Ligand Binding Site [chemical binding]; other site
568709005692	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
568709005693	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
568709005694	active site
568709005695	homotetramer interface [polypeptide binding]; other site
568709005696	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
568709005697	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
568709005698	DJ-1 family protein; Region: not_thiJ; TIGR01383
568709005699	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
568709005700	conserved cys residue [active]
568709005701	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
568709005702	Ferritin-like domain; Region: Ferritin; pfam00210
568709005703	ferroxidase diiron center [ion binding]; other site
568709005704	hypothetical protein; Provisional; Region: PRK09273
568709005705	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
568709005706	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
568709005707	YecR-like lipoprotein; Region: YecR; pfam13992
568709005708	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
568709005709	Ferritin-like domain; Region: Ferritin; pfam00210
568709005710	ferroxidase diiron center [ion binding]; other site
568709005711	probable metal-binding protein; Region: matur_matur; TIGR03853
568709005712	tyrosine transporter TyrP; Provisional; Region: PRK15132
568709005713	aromatic amino acid transport protein; Region: araaP; TIGR00837
568709005714	hypothetical protein; Provisional; Region: PRK10396
568709005715	yecA family protein; Region: ygfB_yecA; TIGR02292
568709005716	SEC-C motif; Region: SEC-C; pfam02810
568709005717	glucose-6-phosphate 1-dehydrogenase; Region: PLN02640
568709005718	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
568709005719	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
568709005720	NlpC/P60 family; Region: NLPC_P60; cl17555
568709005722	it has a frameshift after residue 17
568709005723	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
568709005724	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
568709005725	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
568709005726	GIY-YIG motif/motif A; other site
568709005727	active site
568709005728	catalytic site [active]
568709005729	putative DNA binding site [nucleotide binding]; other site
568709005730	metal binding site [ion binding]; metal-binding site
568709005731	UvrB/uvrC motif; Region: UVR; pfam02151
568709005732	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
568709005733	Helix-hairpin-helix motif; Region: HHH; pfam00633
568709005734	response regulator; Provisional; Region: PRK09483
568709005735	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709005736	active site
568709005737	phosphorylation site [posttranslational modification]
568709005738	intermolecular recognition site; other site
568709005739	dimerization interface [polypeptide binding]; other site
568709005740	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709005741	DNA binding residues [nucleotide binding]
568709005742	dimerization interface [polypeptide binding]; other site
568709005743	hypothetical protein; Provisional; Region: PRK10613
568709005744	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
568709005745	Autoinducer binding domain; Region: Autoind_bind; pfam03472
568709005746	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709005747	DNA binding residues [nucleotide binding]
568709005748	dimerization interface [polypeptide binding]; other site
568709005749	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
568709005750	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
568709005751	Walker A/P-loop; other site
568709005752	ATP binding site [chemical binding]; other site
568709005753	Q-loop/lid; other site
568709005754	ABC transporter signature motif; other site
568709005755	Walker B; other site
568709005756	D-loop; other site
568709005757	H-loop/switch region; other site
568709005758	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
568709005759	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568709005760	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709005761	dimer interface [polypeptide binding]; other site
568709005762	conserved gate region; other site
568709005763	putative PBP binding loops; other site
568709005764	ABC-ATPase subunit interface; other site
568709005765	D-cysteine desulfhydrase; Validated; Region: PRK03910
568709005766	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
568709005767	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709005768	catalytic residue [active]
568709005769	cystine transporter subunit; Provisional; Region: PRK11260
568709005770	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709005771	substrate binding pocket [chemical binding]; other site
568709005772	membrane-bound complex binding site; other site
568709005773	hinge residues; other site
568709005774	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
568709005775	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
568709005776	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
568709005777	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
568709005778	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
568709005779	DNA binding residues [nucleotide binding]
568709005780	Transposase IS200 like; Region: Y1_Tnp; pfam01797
568709005781	flagellin; Validated; Region: PRK08026
568709005782	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
568709005783	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
568709005784	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
568709005785	flagellar capping protein; Reviewed; Region: fliD; PRK08032
568709005786	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
568709005787	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
568709005788	flagellar protein FliS; Validated; Region: fliS; PRK05685
568709005789	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
568709005790	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
568709005791	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
568709005792	active site
568709005793	Na/Ca binding site [ion binding]; other site
568709005794	catalytic site [active]
568709005795	lipoprotein; Provisional; Region: PRK10397
568709005796	putative inner membrane protein; Provisional; Region: PRK11099
568709005797	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
568709005798	CPxP  motif; other site
568709005799	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
568709005800	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
568709005801	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
568709005802	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
568709005803	flagellar motor switch protein FliG; Region: fliG; TIGR00207
568709005804	FliG C-terminal domain; Region: FliG_C; pfam01706
568709005805	flagellar assembly protein H; Validated; Region: fliH; PRK05687
568709005806	Flagellar assembly protein FliH; Region: FliH; pfam02108
568709005807	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
568709005808	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
568709005809	Walker A motif/ATP binding site; other site
568709005810	Walker B motif; other site
568709005811	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
568709005812	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
568709005813	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
568709005814	flagellar hook-length control protein; Provisional; Region: PRK10118
568709005815	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
568709005816	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
568709005817	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
568709005818	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
568709005819	flagellar motor switch protein; Validated; Region: fliN; PRK05698
568709005820	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
568709005821	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
568709005822	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
568709005823	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
568709005824	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
568709005825	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709005826	DNA binding residues [nucleotide binding]
568709005827	dimerization interface [polypeptide binding]; other site
568709005828	hypothetical protein; Provisional; Region: PRK10708
568709005829	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
568709005830	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
568709005831	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709005832	active site
568709005833	motif I; other site
568709005834	motif II; other site
568709005835	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
568709005836	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568709005837	metal binding site [ion binding]; metal-binding site
568709005838	active site
568709005839	I-site; other site
568709005840	Uncharacterized small protein [Function unknown]; Region: COG5475
568709005841	hypothetical protein; Provisional; Region: PRK10062
568709005842	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
568709005843	EamA-like transporter family; Region: EamA; pfam00892
568709005844	EamA-like transporter family; Region: EamA; pfam00892
568709005845	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
568709005846	additional DNA contacts [nucleotide binding]; other site
568709005847	mismatch recognition site; other site
568709005848	active site
568709005849	zinc binding site [ion binding]; other site
568709005850	DNA intercalation site [nucleotide binding]; other site
568709005851	DNA cytosine methylase; Provisional; Region: PRK10458
568709005852	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
568709005853	cofactor binding site; other site
568709005854	DNA binding site [nucleotide binding]
568709005855	substrate interaction site [chemical binding]; other site
568709005856	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
568709005857	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568709005858	Zn2+ binding site [ion binding]; other site
568709005859	Mg2+ binding site [ion binding]; other site
568709005860	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
568709005861	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
568709005862	trimer interface [polypeptide binding]; other site
568709005863	eyelet of channel; other site
568709005864	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
568709005865	DNA-binding site [nucleotide binding]; DNA binding site
568709005866	RNA-binding motif; other site
568709005867	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
568709005868	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
568709005869	active site
568709005870	DNA binding site [nucleotide binding]
568709005871	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
568709005872	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
568709005873	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
568709005874	Catalytic site [active]
568709005875	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
568709005876	DNA-binding interface [nucleotide binding]; DNA binding site
568709005877	type III secretion system protein; Provisional; Region: PRK15383
568709005878	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
568709005879	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
568709005880	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
568709005881	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
568709005882	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
568709005883	Baseplate J-like protein; Region: Baseplate_J; cl01294
568709005884	Phage protein GP46; Region: GP46; pfam07409
568709005885	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; pfam06890
568709005886	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
568709005887	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
568709005888	Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228
568709005889	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
568709005890	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
568709005891	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
568709005892	Phage tail tube protein; Region: Tail_tube; pfam10618
568709005893	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
568709005894	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
568709005895	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
568709005897	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
568709005898	Phage capsid family; Region: Phage_capsid; pfam05065
568709005899	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
568709005900	Phage-related protein [Function unknown]; Region: COG4695
568709005901	Phage portal protein; Region: Phage_portal; pfam04860
568709005902	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
568709005903	Phage terminase, small subunit; Region: Terminase_4; pfam05119
568709005904	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
568709005905	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
568709005906	active site
568709005907	KilA-N domain; Region: KilA-N; pfam04383
568709005908	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
568709005909	Predicted chitinase [General function prediction only]; Region: COG3179
568709005910	catalytic residue [active]
568709005911	Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106
568709005912	Protein of unknown function (DUF968); Region: DUF968; pfam06147
568709005913	KilA-N domain; Region: KilA-N; pfam04383
568709005914	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
568709005915	PerC transcriptional activator; Region: PerC; pfam06069
568709005916	Helix-turn-helix domain; Region: HTH_36; pfam13730
568709005917	Ash protein family; Region: Phage_ASH; pfam10554
568709005918	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
568709005919	Predicted transcriptional regulator [Transcription]; Region: COG2932
568709005920	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709005921	non-specific DNA binding site [nucleotide binding]; other site
568709005922	salt bridge; other site
568709005923	sequence-specific DNA binding site [nucleotide binding]; other site
568709005924	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
568709005925	Catalytic site [active]
568709005926	Uncharacterized conserved protein (DUF2303); Region: DUF2303; pfam10065
568709005927	HD domain; Region: HD_3; cl17350
568709005928	Protein of unknown function DUF262; Region: DUF262; pfam03235
568709005929	Uncharacterized conserved protein [Function unknown]; Region: COG1479
568709005930	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
568709005931	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
568709005932	active site
568709005933	catalytic site [active]
568709005934	substrate binding site [chemical binding]; other site
568709005935	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
568709005936	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
568709005937	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
568709005938	dimer interface [polypeptide binding]; other site
568709005939	active site
568709005940	Int/Topo IB signature motif; other site
568709005941	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
568709005942	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
568709005943	putative protease; Region: PHA00666
568709005944	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
568709005945	Integrase; Region: Integrase_1; pfam12835
568709005946	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
568709005947	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
568709005948	Sel1 repeat; Region: Sel1; pfam08238
568709005949	Sel1-like repeats; Region: SEL1; smart00671
568709005950	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
568709005951	ADP-heptose:LPS heptosyl transferase I; Provisional; Region: PRK10964; cl15782
568709005952	AMP nucleosidase; Provisional; Region: PRK08292
568709005953	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
568709005954	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
568709005955	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
568709005957	MATE family multidrug exporter; Provisional; Region: PRK10189
568709005958	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
568709005959	L,D-transpeptidase; Provisional; Region: PRK10190
568709005960	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
568709005961	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
568709005962	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
568709005963	putative dimer interface [polypeptide binding]; other site
568709005964	active site pocket [active]
568709005965	putative cataytic base [active]
568709005966	cobalamin synthase; Reviewed; Region: cobS; PRK00235
568709005967	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
568709005968	homotrimer interface [polypeptide binding]; other site
568709005969	Walker A motif; other site
568709005970	GTP binding site [chemical binding]; other site
568709005971	Walker B motif; other site
568709005972	cobyric acid synthase; Provisional; Region: PRK00784
568709005973	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
568709005974	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
568709005975	catalytic triad [active]
568709005976	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
568709005977	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
568709005978	Walker A/P-loop; other site
568709005979	ATP binding site [chemical binding]; other site
568709005980	Q-loop/lid; other site
568709005981	ABC transporter signature motif; other site
568709005982	Walker B; other site
568709005983	D-loop; other site
568709005984	H-loop/switch region; other site
568709005985	cobalt transport protein CbiQ; Provisional; Region: PRK15485
568709005986	cobalt transport protein CbiN; Provisional; Region: PRK02898
568709005987	cobalt transport protein CbiM; Validated; Region: PRK08319
568709005988	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
568709005989	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
568709005990	active site
568709005991	SAM binding site [chemical binding]; other site
568709005992	homodimer interface [polypeptide binding]; other site
568709005993	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
568709005994	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
568709005995	active site
568709005996	C-terminal domain interface [polypeptide binding]; other site
568709005997	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
568709005998	active site
568709005999	N-terminal domain interface [polypeptide binding]; other site
568709006000	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
568709006001	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
568709006002	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
568709006003	active site
568709006004	SAM binding site [chemical binding]; other site
568709006005	homodimer interface [polypeptide binding]; other site
568709006006	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
568709006007	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
568709006008	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
568709006009	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
568709006010	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
568709006011	active site
568709006012	SAM binding site [chemical binding]; other site
568709006013	homodimer interface [polypeptide binding]; other site
568709006014	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
568709006015	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709006016	S-adenosylmethionine binding site [chemical binding]; other site
568709006017	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
568709006018	active site
568709006019	putative homodimer interface [polypeptide binding]; other site
568709006020	SAM binding site [chemical binding]; other site
568709006021	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
568709006022	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
568709006023	Precorrin-8X methylmutase; Region: CbiC; pfam02570
568709006024	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
568709006025	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
568709006026	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
568709006027	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
568709006028	catalytic triad [active]
568709006029	Sensory domain found in PocR; Region: PocR; pfam10114
568709006030	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
568709006031	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709006032	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568709006033	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709006034	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
568709006035	amphipathic channel; other site
568709006036	Asn-Pro-Ala signature motifs; other site
568709006037	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
568709006038	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
568709006039	Hexamer interface [polypeptide binding]; other site
568709006040	Putative hexagonal pore residue; other site
568709006041	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutL; COG4816
568709006042	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
568709006043	putative hexamer interface [polypeptide binding]; other site
568709006044	putative hexagonal pore; other site
568709006045	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
568709006046	putative hexamer interface [polypeptide binding]; other site
568709006047	putative hexagonal pore; other site
568709006048	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
568709006049	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
568709006050	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
568709006051	alpha-beta subunit interface [polypeptide binding]; other site
568709006052	alpha-gamma subunit interface [polypeptide binding]; other site
568709006053	active site
568709006054	substrate and K+ binding site; other site
568709006055	K+ binding site [ion binding]; other site
568709006056	cobalamin binding site [chemical binding]; other site
568709006057	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
568709006058	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
568709006059	Cell division protein FtsA; Region: FtsA; cl17206
568709006060	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
568709006061	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
568709006062	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
568709006063	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
568709006064	Hexamer interface [polypeptide binding]; other site
568709006065	Putative hexagonal pore residue; other site
568709006066	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
568709006067	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
568709006068	putative hexamer interface [polypeptide binding]; other site
568709006069	putative hexagonal pore; other site
568709006070	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
568709006071	Propanediol utilisation protein PduL; Region: PduL; pfam06130
568709006072	Propanediol utilisation protein PduL; Region: PduL; pfam06130
568709006073	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
568709006074	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
568709006075	Hexamer/Pentamer interface [polypeptide binding]; other site
568709006076	central pore; other site
568709006077	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
568709006078	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
568709006079	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
568709006080	putative catalytic cysteine [active]
568709006081	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
568709006082	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
568709006083	putative active site [active]
568709006084	metal binding site [ion binding]; metal-binding site
568709006085	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
568709006086	SLBB domain; Region: SLBB; pfam10531
568709006087	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
568709006088	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
568709006089	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
568709006090	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
568709006091	putative hexamer interface [polypeptide binding]; other site
568709006092	putative hexagonal pore; other site
568709006093	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
568709006094	putative hexamer interface [polypeptide binding]; other site
568709006095	putative hexagonal pore; other site
568709006096	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
568709006097	putative hexamer interface [polypeptide binding]; other site
568709006098	putative hexagonal pore; other site
568709006099	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
568709006100	G3 box; other site
568709006101	Switch II region; other site
568709006102	GTP/Mg2+ binding site [chemical binding]; other site
568709006103	G4 box; other site
568709006104	G5 box; other site
568709006105	propionate kinase; Reviewed; Region: PRK12397
568709006106	propionate/acetate kinase; Provisional; Region: PRK12379
568709006107	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
568709006108	hypothetical protein; Provisional; Region: PRK05423
568709006109	Predicted membrane protein [Function unknown]; Region: COG1289
568709006110	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
568709006111	DNA gyrase inhibitor; Provisional; Region: PRK10016
568709006112	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
568709006113	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
568709006114	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
568709006115	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
568709006116	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
568709006117	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
568709006118	4Fe-4S binding domain; Region: Fer4; cl02805
568709006119	thiosulfate reductase PhsA; Provisional; Region: PRK15488
568709006120	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
568709006121	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
568709006122	putative [Fe4-S4] binding site [ion binding]; other site
568709006123	putative molybdopterin cofactor binding site [chemical binding]; other site
568709006124	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709006125	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
568709006126	putative molybdopterin cofactor binding site; other site
568709006127	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
568709006128	E3 ubiquitin-protein ligase SopA; Provisional; Region: PRK15377
568709006129	SopA-like central domain; Region: SopA; pfam13981
568709006130	SopA-like catalytic domain; Region: SopA_C; pfam13979
568709006131	exonuclease I; Provisional; Region: sbcB; PRK11779
568709006132	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
568709006133	active site
568709006134	catalytic site [active]
568709006135	substrate binding site [chemical binding]; other site
568709006136	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
568709006137	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
568709006138	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709006139	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
568709006140	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709006141	dimerization interface [polypeptide binding]; other site
568709006142	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
568709006143	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
568709006144	putative NAD(P) binding site [chemical binding]; other site
568709006145	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
568709006146	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
568709006147	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
568709006148	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
568709006149	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
568709006150	NAD binding site [chemical binding]; other site
568709006151	dimerization interface [polypeptide binding]; other site
568709006152	product binding site; other site
568709006153	substrate binding site [chemical binding]; other site
568709006154	zinc binding site [ion binding]; other site
568709006155	catalytic residues [active]
568709006156	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
568709006157	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709006158	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709006159	homodimer interface [polypeptide binding]; other site
568709006160	catalytic residue [active]
568709006161	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
568709006162	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709006163	active site
568709006164	motif I; other site
568709006165	motif II; other site
568709006166	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
568709006167	putative active site pocket [active]
568709006168	4-fold oligomerization interface [polypeptide binding]; other site
568709006169	metal binding residues [ion binding]; metal-binding site
568709006170	3-fold/trimer interface [polypeptide binding]; other site
568709006171	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
568709006172	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
568709006173	putative active site [active]
568709006174	oxyanion strand; other site
568709006175	catalytic triad [active]
568709006176	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
568709006177	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
568709006178	catalytic residues [active]
568709006179	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
568709006180	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
568709006181	substrate binding site [chemical binding]; other site
568709006182	glutamase interaction surface [polypeptide binding]; other site
568709006183	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
568709006184	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
568709006185	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
568709006186	metal binding site [ion binding]; metal-binding site
568709006187	chain length determinant protein WzzB; Provisional; Region: PRK15471
568709006188	Chain length determinant protein; Region: Wzz; pfam02706
568709006189	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
568709006190	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
568709006191	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
568709006192	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
568709006193	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
568709006194	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
568709006195	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
568709006196	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
568709006197	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
568709006198	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
568709006199	Bacterial sugar transferase; Region: Bac_transf; pfam02397
568709006200	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
568709006201	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
568709006202	active site
568709006203	substrate binding site [chemical binding]; other site
568709006204	metal binding site [ion binding]; metal-binding site
568709006205	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
568709006206	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
568709006207	Substrate binding site; other site
568709006208	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
568709006209	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
568709006210	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
568709006211	active site
568709006212	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568709006213	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568709006214	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
568709006215	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
568709006216	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
568709006217	active site
568709006218	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
568709006219	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
568709006220	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
568709006221	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
568709006222	NAD(P) binding site [chemical binding]; other site
568709006223	active site
568709006224	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
568709006225	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
568709006226	inhibitor-cofactor binding pocket; inhibition site
568709006227	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709006228	catalytic residue [active]
568709006229	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
568709006230	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
568709006231	NAD binding site [chemical binding]; other site
568709006232	homotetramer interface [polypeptide binding]; other site
568709006233	homodimer interface [polypeptide binding]; other site
568709006234	substrate binding site [chemical binding]; other site
568709006235	active site
568709006236	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
568709006237	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
568709006238	substrate binding site; other site
568709006239	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
568709006240	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
568709006241	catalytic loop [active]
568709006242	iron binding site [ion binding]; other site
568709006243	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
568709006244	FAD binding pocket [chemical binding]; other site
568709006245	FAD binding motif [chemical binding]; other site
568709006246	phosphate binding motif [ion binding]; other site
568709006247	beta-alpha-beta structure motif; other site
568709006248	NAD binding pocket [chemical binding]; other site
568709006249	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
568709006250	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
568709006251	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
568709006252	substrate binding site; other site
568709006253	tetramer interface; other site
568709006254	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
568709006255	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
568709006256	NADP binding site [chemical binding]; other site
568709006257	active site
568709006258	putative substrate binding site [chemical binding]; other site
568709006259	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
568709006260	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
568709006261	NAD binding site [chemical binding]; other site
568709006262	substrate binding site [chemical binding]; other site
568709006263	homodimer interface [polypeptide binding]; other site
568709006264	active site
568709006265	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
568709006266	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
568709006267	active site
568709006268	tetramer interface; other site
568709006269	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
568709006270	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
568709006271	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
568709006272	putative ADP-binding pocket [chemical binding]; other site
568709006273	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
568709006274	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
568709006275	colanic acid exporter; Provisional; Region: PRK10459
568709006276	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
568709006277	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
568709006278	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
568709006279	phosphomannomutase CpsG; Provisional; Region: PRK15414
568709006280	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
568709006281	active site
568709006282	substrate binding site [chemical binding]; other site
568709006283	metal binding site [ion binding]; metal-binding site
568709006284	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
568709006285	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
568709006286	Substrate binding site; other site
568709006287	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
568709006288	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
568709006289	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
568709006290	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
568709006291	active site
568709006292	GDP-Mannose binding site [chemical binding]; other site
568709006293	dimer interface [polypeptide binding]; other site
568709006294	modified nudix motif
568709006295	metal binding site [ion binding]; metal-binding site
568709006296	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
568709006297	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
568709006298	NADP binding site [chemical binding]; other site
568709006299	active site
568709006300	putative substrate binding site [chemical binding]; other site
568709006301	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
568709006302	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
568709006303	NADP-binding site; other site
568709006304	homotetramer interface [polypeptide binding]; other site
568709006305	substrate binding site [chemical binding]; other site
568709006306	homodimer interface [polypeptide binding]; other site
568709006307	active site
568709006308	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
568709006309	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
568709006310	putative trimer interface [polypeptide binding]; other site
568709006311	putative active site [active]
568709006312	putative substrate binding site [chemical binding]; other site
568709006313	putative CoA binding site [chemical binding]; other site
568709006314	putative glycosyl transferase; Provisional; Region: PRK10063
568709006315	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
568709006316	metal-binding site
568709006317	putative colanic acid biosynthesis protein; Provisional; Region: wcaD; cl08075
568709006318	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
568709006319	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
568709006320	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
568709006321	putative acyl transferase; Provisional; Region: PRK10191
568709006322	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
568709006323	trimer interface [polypeptide binding]; other site
568709006324	active site
568709006325	substrate binding site [chemical binding]; other site
568709006326	CoA binding site [chemical binding]; other site
568709006327	putative glycosyl transferase; Provisional; Region: PRK10018
568709006328	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
568709006329	active site
568709006330	tyrosine kinase; Provisional; Region: PRK11519
568709006331	Chain length determinant protein; Region: Wzz; pfam02706
568709006332	Chain length determinant protein; Region: Wzz; cl15801
568709006333	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
568709006334	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
568709006335	Low molecular weight phosphatase family; Region: LMWPc; cd00115
568709006336	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
568709006337	active site
568709006338	polysaccharide export protein Wza; Provisional; Region: PRK15078
568709006339	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
568709006340	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
568709006341	FOG: CBS domain [General function prediction only]; Region: COG0517
568709006342	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
568709006343	Transporter associated domain; Region: CorC_HlyC; smart01091
568709006344	putative assembly protein; Provisional; Region: PRK10833
568709006345	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
568709006346	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
568709006347	trimer interface [polypeptide binding]; other site
568709006348	active site
568709006349	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
568709006350	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
568709006351	ATP-binding site [chemical binding]; other site
568709006352	Sugar specificity; other site
568709006353	Pyrimidine base specificity; other site
568709006354	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
568709006355	PAS domain S-box; Region: sensory_box; TIGR00229
568709006356	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
568709006357	putative active site [active]
568709006358	heme pocket [chemical binding]; other site
568709006359	PAS domain S-box; Region: sensory_box; TIGR00229
568709006360	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
568709006361	putative active site [active]
568709006362	heme pocket [chemical binding]; other site
568709006363	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
568709006364	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568709006365	metal binding site [ion binding]; metal-binding site
568709006366	active site
568709006367	I-site; other site
568709006368	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709006369	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
568709006370	AlkA N-terminal domain; Region: AlkA_N; pfam06029
568709006371	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
568709006372	minor groove reading motif; other site
568709006373	helix-hairpin-helix signature motif; other site
568709006374	substrate binding pocket [chemical binding]; other site
568709006375	active site
568709006376	putative chaperone; Provisional; Region: PRK11678
568709006377	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
568709006378	nucleotide binding site [chemical binding]; other site
568709006379	putative NEF/HSP70 interaction site [polypeptide binding]; other site
568709006380	SBD interface [polypeptide binding]; other site
568709006381	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
568709006382	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
568709006383	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709006384	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
568709006385	Protein export membrane protein; Region: SecD_SecF; cl14618
568709006386	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
568709006387	putative transporter; Provisional; Region: PRK10504
568709006388	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709006389	putative substrate translocation pore; other site
568709006390	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
568709006391	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709006392	dimerization interface [polypeptide binding]; other site
568709006393	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709006394	dimer interface [polypeptide binding]; other site
568709006395	phosphorylation site [posttranslational modification]
568709006396	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709006397	ATP binding site [chemical binding]; other site
568709006398	Mg2+ binding site [ion binding]; other site
568709006399	G-X-G motif; other site
568709006400	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
568709006401	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709006402	active site
568709006403	phosphorylation site [posttranslational modification]
568709006404	intermolecular recognition site; other site
568709006405	dimerization interface [polypeptide binding]; other site
568709006406	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709006407	DNA binding site [nucleotide binding]
568709006408	PcfJ-like protein; Region: PcfJ; pfam14284
568709006410	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
568709006411	putative protease; Provisional; Region: PRK15452
568709006412	Peptidase family U32; Region: Peptidase_U32; pfam01136
568709006413	type III secretion system protein; Provisional; Region: PRK15383
568709006414	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
568709006415	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
568709006416	lipid kinase; Reviewed; Region: PRK13054
568709006417	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
568709006418	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
568709006419	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
568709006420	putative active site; other site
568709006421	catalytic residue [active]
568709006422	nucleoside transporter; Region: 2A0110; TIGR00889
568709006423	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709006424	putative substrate translocation pore; other site
568709006425	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
568709006426	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709006427	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
568709006428	substrate binding site [chemical binding]; other site
568709006429	ATP binding site [chemical binding]; other site
568709006430	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
568709006431	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709006432	DNA-binding site [nucleotide binding]; DNA binding site
568709006433	UTRA domain; Region: UTRA; pfam07702
568709006434	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
568709006435	dimer interface [polypeptide binding]; other site
568709006436	substrate binding site [chemical binding]; other site
568709006437	ATP binding site [chemical binding]; other site
568709006438	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
568709006439	substrate binding site [chemical binding]; other site
568709006440	multimerization interface [polypeptide binding]; other site
568709006441	ATP binding site [chemical binding]; other site
568709006442	Predicted integral membrane protein [Function unknown]; Region: COG5455
568709006443	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
568709006444	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
568709006445	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
568709006446	PapC N-terminal domain; Region: PapC_N; pfam13954
568709006447	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709006448	PapC C-terminal domain; Region: PapC_C; pfam13953
568709006449	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
568709006450	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709006451	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709006452	fimbrial chaperone protein; Provisional; Region: PRK15220
568709006453	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
568709006454	antiporter inner membrane protein; Provisional; Region: PRK11670
568709006455	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
568709006456	Walker A motif; other site
568709006457	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
568709006458	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
568709006459	active site
568709006460	HIGH motif; other site
568709006461	KMSKS motif; other site
568709006462	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
568709006463	tRNA binding surface [nucleotide binding]; other site
568709006464	anticodon binding site; other site
568709006465	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
568709006466	dimer interface [polypeptide binding]; other site
568709006467	putative tRNA-binding site [nucleotide binding]; other site
568709006468	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
568709006469	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
568709006470	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
568709006471	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
568709006472	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
568709006473	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
568709006474	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709006475	active site
568709006476	phosphorylation site [posttranslational modification]
568709006477	intermolecular recognition site; other site
568709006478	dimerization interface [polypeptide binding]; other site
568709006479	LytTr DNA-binding domain; Region: LytTR; pfam04397
568709006480	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
568709006481	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
568709006482	GAF domain; Region: GAF; pfam01590
568709006483	Histidine kinase; Region: His_kinase; pfam06580
568709006484	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709006485	ATP binding site [chemical binding]; other site
568709006486	Mg2+ binding site [ion binding]; other site
568709006487	G-X-G motif; other site
568709006488	transcriptional regulator MirA; Provisional; Region: PRK15043
568709006489	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
568709006490	DNA binding residues [nucleotide binding]
568709006491	hypothetical protein; Provisional; Region: PRK13681
568709006492	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
568709006493	putative PBP binding loops; other site
568709006494	ABC-ATPase subunit interface; other site
568709006495	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
568709006496	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
568709006497	Walker A/P-loop; other site
568709006498	ATP binding site [chemical binding]; other site
568709006499	Q-loop/lid; other site
568709006500	ABC transporter signature motif; other site
568709006501	Walker B; other site
568709006502	D-loop; other site
568709006503	H-loop/switch region; other site
568709006504	CBS domain; Region: CBS; pfam00571
568709006505	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709006506	dimer interface [polypeptide binding]; other site
568709006507	conserved gate region; other site
568709006508	ABC-ATPase subunit interface; other site
568709006509	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
568709006510	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
568709006511	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
568709006512	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
568709006513	D-lactate dehydrogenase; Provisional; Region: PRK11183
568709006514	FAD binding domain; Region: FAD_binding_4; pfam01565
568709006515	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
568709006517	region highly similar to CT18 ST46 P4-family prophage
568709006518	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
568709006519	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
568709006520	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
568709006521	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
568709006522	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
568709006523	oxidoreductase; Provisional; Region: PRK12743
568709006524	classical (c) SDRs; Region: SDR_c; cd05233
568709006525	NAD(P) binding site [chemical binding]; other site
568709006526	active site
568709006527	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
568709006528	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
568709006529	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
568709006530	FMN binding site [chemical binding]; other site
568709006531	active site
568709006532	catalytic residues [active]
568709006533	substrate binding site [chemical binding]; other site
568709006534	salicylate hydroxylase; Provisional; Region: PRK08163
568709006535	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
568709006536	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
568709006537	maleylacetoacetate isomerase; Region: maiA; TIGR01262
568709006538	C-terminal domain interface [polypeptide binding]; other site
568709006539	GSH binding site (G-site) [chemical binding]; other site
568709006540	putative dimer interface [polypeptide binding]; other site
568709006541	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
568709006542	dimer interface [polypeptide binding]; other site
568709006543	N-terminal domain interface [polypeptide binding]; other site
568709006544	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
568709006545	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
568709006546	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
568709006547	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
568709006548	Cupin domain; Region: Cupin_2; pfam07883
568709006549	Cupin domain; Region: Cupin_2; pfam07883
568709006550	benzoate transport; Region: 2A0115; TIGR00895
568709006551	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709006552	putative substrate translocation pore; other site
568709006553	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
568709006554	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709006555	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709006556	dimerization interface [polypeptide binding]; other site
568709006557	hypothetical protein; Provisional; Region: PRK01821
568709006558	hypothetical protein; Provisional; Region: PRK10711
568709006559	cytidine deaminase; Provisional; Region: PRK09027
568709006560	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
568709006561	active site
568709006562	catalytic motif [active]
568709006563	Zn binding site [ion binding]; other site
568709006564	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
568709006565	active site
568709006566	catalytic motif [active]
568709006567	Zn binding site [ion binding]; other site
568709006568	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
568709006569	putative active site [active]
568709006570	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
568709006571	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
568709006572	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568709006573	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709006574	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
568709006575	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
568709006576	homodimer interface [polypeptide binding]; other site
568709006577	active site
568709006578	FMN binding site [chemical binding]; other site
568709006579	substrate binding site [chemical binding]; other site
568709006580	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
568709006581	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
568709006582	TM-ABC transporter signature motif; other site
568709006583	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
568709006584	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
568709006585	Walker A/P-loop; other site
568709006586	ATP binding site [chemical binding]; other site
568709006587	Q-loop/lid; other site
568709006588	ABC transporter signature motif; other site
568709006589	Walker B; other site
568709006590	D-loop; other site
568709006591	H-loop/switch region; other site
568709006592	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
568709006593	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
568709006594	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
568709006595	ligand binding site [chemical binding]; other site
568709006596	calcium binding site [ion binding]; other site
568709006597	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
568709006598	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709006599	DNA binding site [nucleotide binding]
568709006600	domain linker motif; other site
568709006601	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
568709006602	dimerization interface (closed form) [polypeptide binding]; other site
568709006603	ligand binding site [chemical binding]; other site
568709006604	Predicted membrane protein [Function unknown]; Region: COG2311
568709006605	hypothetical protein; Provisional; Region: PRK10835
568709006606	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
568709006607	GTP cyclohydrolase I; Provisional; Region: PLN03044
568709006608	active site
568709006609	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
568709006610	S-formylglutathione hydrolase; Region: PLN02442
568709006611	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709006612	non-specific DNA binding site [nucleotide binding]; other site
568709006613	salt bridge; other site
568709006614	sequence-specific DNA binding site [nucleotide binding]; other site
568709006615	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
568709006616	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
568709006617	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
568709006618	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
568709006619	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
568709006620	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709006621	motif II; other site
568709006622	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
568709006623	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709006624	putative substrate translocation pore; other site
568709006625	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
568709006626	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
568709006627	N-terminal plug; other site
568709006628	ligand-binding site [chemical binding]; other site
568709006629	lysine transporter; Provisional; Region: PRK10836
568709006630	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
568709006631	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709006632	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
568709006633	putative dimerization interface [polypeptide binding]; other site
568709006634	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
568709006635	endonuclease IV; Provisional; Region: PRK01060
568709006636	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
568709006637	AP (apurinic/apyrimidinic) site pocket; other site
568709006638	DNA interaction; other site
568709006639	Metal-binding active site; metal-binding site
568709006640	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
568709006641	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
568709006642	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568709006643	active site
568709006644	P-loop; other site
568709006645	phosphorylation site [posttranslational modification]
568709006646	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
568709006647	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
568709006648	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
568709006649	putative substrate binding site [chemical binding]; other site
568709006650	putative ATP binding site [chemical binding]; other site
568709006651	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
568709006652	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709006653	active site
568709006654	phosphorylation site [posttranslational modification]
568709006655	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
568709006656	dimerization domain swap beta strand [polypeptide binding]; other site
568709006657	regulatory protein interface [polypeptide binding]; other site
568709006658	active site
568709006659	regulatory phosphorylation site [posttranslational modification]; other site
568709006660	sugar efflux transporter B; Provisional; Region: PRK15011
568709006661	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709006662	putative substrate translocation pore; other site
568709006663	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
568709006664	Flagellin N-methylase; Region: FliB; cl00497
568709006665	elongation factor P; Provisional; Region: PRK04542
568709006666	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
568709006667	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
568709006668	RNA binding site [nucleotide binding]; other site
568709006669	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
568709006670	RNA binding site [nucleotide binding]; other site
568709006671	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
568709006672	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
568709006673	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
568709006674	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
568709006675	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
568709006676	active site
568709006677	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
568709006678	NlpC/P60 family; Region: NLPC_P60; pfam00877
568709006679	phage resistance protein; Provisional; Region: PRK10551
568709006680	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
568709006681	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709006682	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
568709006683	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
568709006684	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
568709006685	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709006686	dimer interface [polypeptide binding]; other site
568709006687	conserved gate region; other site
568709006688	putative PBP binding loops; other site
568709006689	ABC-ATPase subunit interface; other site
568709006690	microcin C ABC transporter permease; Provisional; Region: PRK15021
568709006691	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709006692	dimer interface [polypeptide binding]; other site
568709006693	conserved gate region; other site
568709006694	ABC-ATPase subunit interface; other site
568709006695	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
568709006696	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709006697	Walker A/P-loop; other site
568709006698	ATP binding site [chemical binding]; other site
568709006699	Q-loop/lid; other site
568709006700	ABC transporter signature motif; other site
568709006701	Walker B; other site
568709006702	D-loop; other site
568709006703	H-loop/switch region; other site
568709006704	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
568709006705	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709006706	Walker A/P-loop; other site
568709006707	ATP binding site [chemical binding]; other site
568709006708	Q-loop/lid; other site
568709006709	ABC transporter signature motif; other site
568709006710	Walker B; other site
568709006711	D-loop; other site
568709006712	H-loop/switch region; other site
568709006713	hypothetical protein; Provisional; Region: PRK11835
568709006714	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709006715	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
568709006716	putative substrate translocation pore; other site
568709006717	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
568709006718	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568709006719	RNA binding surface [nucleotide binding]; other site
568709006720	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
568709006721	active site
568709006722	uracil binding [chemical binding]; other site
568709006723	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
568709006724	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568709006725	ATP binding site [chemical binding]; other site
568709006726	putative Mg++ binding site [ion binding]; other site
568709006727	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709006728	nucleotide binding region [chemical binding]; other site
568709006729	ATP-binding site [chemical binding]; other site
568709006730	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
568709006731	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
568709006732	5S rRNA interface [nucleotide binding]; other site
568709006733	CTC domain interface [polypeptide binding]; other site
568709006734	L16 interface [polypeptide binding]; other site
568709006735	Nucleoid-associated protein [General function prediction only]; Region: COG3081
568709006736	nucleoid-associated protein NdpA; Validated; Region: PRK00378
568709006737	hypothetical protein; Provisional; Region: PRK13689
568709006738	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
568709006739	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
568709006740	Sulfatase; Region: Sulfatase; cl17466
568709006741	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
568709006742	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
568709006743	Catalytic site [active]
568709006744	DinI-like family; Region: DinI; cl11630
568709006746	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
568709006747	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
568709006748	Phage T4 tail fibre; Region: Phage_T4_gp36; pfam03903
568709006749	Phage head maturation protease [General function prediction only]; Region: COG3740
568709006750	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
568709006751	Phage-related protein [Function unknown]; Region: COG4695; cl01923
568709006752	Predicted P-loop ATPase [General function prediction only]; Region: COG4928
568709006753	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
568709006754	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
568709006755	Protein of unknown function (DUF968); Region: DUF968; pfam06147
568709006756	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
568709006757	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
568709006758	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
568709006759	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
568709006760	Leucine-rich repeats; other site
568709006761	Substrate binding site [chemical binding]; other site
568709006762	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
568709006763	DinI-like family; Region: DinI; cl11630
568709006764	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
568709006765	transcriptional regulator NarP; Provisional; Region: PRK10403
568709006766	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709006767	active site
568709006768	phosphorylation site [posttranslational modification]
568709006769	intermolecular recognition site; other site
568709006770	dimerization interface [polypeptide binding]; other site
568709006771	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709006772	DNA binding residues [nucleotide binding]
568709006773	dimerization interface [polypeptide binding]; other site
568709006774	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
568709006775	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
568709006776	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
568709006777	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709006778	Walker A/P-loop; other site
568709006779	ATP binding site [chemical binding]; other site
568709006780	Q-loop/lid; other site
568709006781	ABC transporter signature motif; other site
568709006782	Walker B; other site
568709006783	D-loop; other site
568709006784	H-loop/switch region; other site
568709006785	cytochrome c-type protein NapC; Provisional; Region: PRK10617
568709006786	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
568709006787	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
568709006788	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
568709006789	4Fe-4S binding domain; Region: Fer4_5; pfam12801
568709006790	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
568709006791	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
568709006792	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
568709006793	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
568709006794	[4Fe-4S] binding site [ion binding]; other site
568709006795	molybdopterin cofactor binding site; other site
568709006796	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
568709006797	molybdopterin cofactor binding site; other site
568709006798	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
568709006799	ferredoxin-type protein; Provisional; Region: PRK10194
568709006800	4Fe-4S binding domain; Region: Fer4; cl02805
568709006801	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
568709006802	secondary substrate binding site; other site
568709006803	primary substrate binding site; other site
568709006804	inhibition loop; other site
568709006805	dimerization interface [polypeptide binding]; other site
568709006806	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
568709006807	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
568709006808	Walker A/P-loop; other site
568709006809	ATP binding site [chemical binding]; other site
568709006810	Q-loop/lid; other site
568709006811	ABC transporter signature motif; other site
568709006812	Walker B; other site
568709006813	D-loop; other site
568709006814	H-loop/switch region; other site
568709006815	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
568709006816	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
568709006817	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
568709006818	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709006819	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
568709006820	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
568709006821	DNA binding site [nucleotide binding]
568709006822	active site
568709006823	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
568709006824	ApbE family; Region: ApbE; pfam02424
568709006825	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
568709006826	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
568709006827	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
568709006828	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709006829	ATP binding site [chemical binding]; other site
568709006830	G-X-G motif; other site
568709006831	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
568709006832	putative binding surface; other site
568709006833	active site
568709006834	transcriptional regulator RcsB; Provisional; Region: PRK10840
568709006835	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709006836	active site
568709006837	phosphorylation site [posttranslational modification]
568709006838	intermolecular recognition site; other site
568709006839	dimerization interface [polypeptide binding]; other site
568709006840	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709006841	DNA binding residues [nucleotide binding]
568709006842	dimerization interface [polypeptide binding]; other site
568709006843	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
568709006844	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709006845	dimer interface [polypeptide binding]; other site
568709006846	phosphorylation site [posttranslational modification]
568709006847	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709006848	ATP binding site [chemical binding]; other site
568709006849	Mg2+ binding site [ion binding]; other site
568709006850	G-X-G motif; other site
568709006851	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
568709006852	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709006853	active site
568709006854	phosphorylation site [posttranslational modification]
568709006855	intermolecular recognition site; other site
568709006856	dimerization interface [polypeptide binding]; other site
568709006857	DNA gyrase subunit A; Validated; Region: PRK05560
568709006858	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
568709006859	CAP-like domain; other site
568709006860	active site
568709006861	primary dimer interface [polypeptide binding]; other site
568709006862	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568709006863	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568709006864	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568709006865	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568709006866	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568709006867	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568709006868	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
568709006869	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
568709006870	active site pocket [active]
568709006871	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
568709006872	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709006873	putative substrate translocation pore; other site
568709006874	Transcriptional regulators [Transcription]; Region: GntR; COG1802
568709006875	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709006876	DNA-binding site [nucleotide binding]; DNA binding site
568709006877	FCD domain; Region: FCD; pfam07729
568709006878	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
568709006879	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709006880	S-adenosylmethionine binding site [chemical binding]; other site
568709006881	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
568709006882	ATP cone domain; Region: ATP-cone; pfam03477
568709006883	Class I ribonucleotide reductase; Region: RNR_I; cd01679
568709006884	active site
568709006885	dimer interface [polypeptide binding]; other site
568709006886	catalytic residues [active]
568709006887	effector binding site; other site
568709006888	R2 peptide binding site; other site
568709006889	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
568709006890	dimer interface [polypeptide binding]; other site
568709006891	putative radical transfer pathway; other site
568709006892	diiron center [ion binding]; other site
568709006893	tyrosyl radical; other site
568709006894	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
568709006895	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
568709006896	catalytic loop [active]
568709006897	iron binding site [ion binding]; other site
568709006898	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568709006899	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709006900	putative substrate translocation pore; other site
568709006901	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
568709006902	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709006903	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568709006904	dimerization interface [polypeptide binding]; other site
568709006905	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
568709006906	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
568709006907	active site
568709006908	catalytic site [active]
568709006909	metal binding site [ion binding]; metal-binding site
568709006910	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
568709006911	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709006912	putative substrate translocation pore; other site
568709006913	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
568709006914	hydroxyglutarate oxidase; Provisional; Region: PRK11728
568709006915	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
568709006916	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
568709006917	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
568709006918	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
568709006919	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
568709006920	Cysteine-rich domain; Region: CCG; pfam02754
568709006921	Cysteine-rich domain; Region: CCG; pfam02754
568709006922	deubiquitinase SseL; Provisional; Region: PRK14848
568709006923	hypothetical protein; Provisional; Region: PRK03673
568709006924	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
568709006925	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709006926	D-galactonate transporter; Region: 2A0114; TIGR00893
568709006927	putative substrate translocation pore; other site
568709006928	L-rhamnonate dehydratase; Provisional; Region: PRK15440
568709006929	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
568709006930	putative active site pocket [active]
568709006931	putative metal binding site [ion binding]; other site
568709006932	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
568709006933	Transcriptional regulator [Transcription]; Region: IclR; COG1414
568709006934	Bacterial transcriptional regulator; Region: IclR; pfam01614
568709006935	hypothetical protein; Provisional; Region: PRK03673
568709006936	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
568709006937	putative MPT binding site; other site
568709006938	Competence-damaged protein; Region: CinA; cl00666
568709006939	YfaZ precursor; Region: YfaZ; pfam07437
568709006940	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
568709006941	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
568709006942	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
568709006943	catalytic core [active]
568709006944	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
568709006945	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
568709006946	inhibitor-cofactor binding pocket; inhibition site
568709006947	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709006948	catalytic residue [active]
568709006949	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
568709006950	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
568709006951	Ligand binding site; other site
568709006952	Putative Catalytic site; other site
568709006953	DXD motif; other site
568709006954	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
568709006955	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
568709006956	active site
568709006957	substrate binding site [chemical binding]; other site
568709006958	cosubstrate binding site; other site
568709006959	catalytic site [active]
568709006960	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
568709006961	active site
568709006962	hexamer interface [polypeptide binding]; other site
568709006963	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
568709006964	NAD binding site [chemical binding]; other site
568709006965	substrate binding site [chemical binding]; other site
568709006966	active site
568709006967	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
568709006968	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
568709006969	putative active site [active]
568709006970	putative catalytic site [active]
568709006971	putative Zn binding site [ion binding]; other site
568709006972	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
568709006973	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
568709006974	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
568709006975	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
568709006976	signal transduction protein PmrD; Provisional; Region: PRK15450
568709006977	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
568709006978	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
568709006979	acyl-activating enzyme (AAE) consensus motif; other site
568709006980	putative AMP binding site [chemical binding]; other site
568709006981	putative active site [active]
568709006982	putative CoA binding site [chemical binding]; other site
568709006983	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
568709006984	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
568709006985	active site
568709006986	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
568709006987	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
568709006988	substrate binding site [chemical binding]; other site
568709006989	oxyanion hole (OAH) forming residues; other site
568709006990	trimer interface [polypeptide binding]; other site
568709006991	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
568709006992	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
568709006993	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
568709006994	dimer interface [polypeptide binding]; other site
568709006995	tetramer interface [polypeptide binding]; other site
568709006996	PYR/PP interface [polypeptide binding]; other site
568709006997	TPP binding site [chemical binding]; other site
568709006998	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
568709006999	TPP-binding site; other site
568709007000	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
568709007001	isochorismate synthases; Region: isochor_syn; TIGR00543
568709007002	hypothetical protein; Provisional; Region: PRK10404
568709007003	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709007004	Coenzyme A binding pocket [chemical binding]; other site
568709007005	ribonuclease BN; Region: true_RNase_BN; TIGR02649
568709007006	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
568709007007	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
568709007008	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709007009	active site
568709007010	phosphorylation site [posttranslational modification]
568709007011	intermolecular recognition site; other site
568709007012	dimerization interface [polypeptide binding]; other site
568709007013	von Willebrand factor; Region: vWF_A; pfam12450
568709007014	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
568709007015	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
568709007016	metal ion-dependent adhesion site (MIDAS); other site
568709007017	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
568709007018	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
568709007019	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
568709007020	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
568709007021	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
568709007022	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
568709007023	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
568709007024	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
568709007025	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
568709007026	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
568709007027	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
568709007028	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
568709007029	4Fe-4S binding domain; Region: Fer4; pfam00037
568709007030	4Fe-4S binding domain; Region: Fer4; pfam00037
568709007031	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
568709007032	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
568709007033	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
568709007034	catalytic loop [active]
568709007035	iron binding site [ion binding]; other site
568709007036	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
568709007037	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
568709007038	[4Fe-4S] binding site [ion binding]; other site
568709007039	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
568709007040	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
568709007041	SLBB domain; Region: SLBB; pfam10531
568709007042	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
568709007043	NADH dehydrogenase subunit E; Validated; Region: PRK07539
568709007044	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
568709007045	putative dimer interface [polypeptide binding]; other site
568709007046	[2Fe-2S] cluster binding site [ion binding]; other site
568709007047	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
568709007048	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
568709007049	NADH dehydrogenase subunit D; Validated; Region: PRK06075
568709007050	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
568709007051	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
568709007052	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
568709007053	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709007054	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
568709007055	putative dimerization interface [polypeptide binding]; other site
568709007056	aminotransferase AlaT; Validated; Region: PRK09265
568709007057	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709007058	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709007059	homodimer interface [polypeptide binding]; other site
568709007060	catalytic residue [active]
568709007061	5'-nucleotidase; Provisional; Region: PRK03826
568709007062	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
568709007063	transmembrane helices; other site
568709007064	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
568709007065	TrkA-C domain; Region: TrkA_C; pfam02080
568709007066	TrkA-C domain; Region: TrkA_C; pfam02080
568709007067	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
568709007068	putative phosphatase; Provisional; Region: PRK11587
568709007069	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709007070	motif II; other site
568709007071	hypothetical protein; Validated; Region: PRK05445
568709007072	hypothetical protein; Provisional; Region: PRK01816
568709007073	propionate/acetate kinase; Provisional; Region: PRK12379
568709007074	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
568709007075	phosphate acetyltransferase; Reviewed; Region: PRK05632
568709007076	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
568709007077	DRTGG domain; Region: DRTGG; pfam07085
568709007078	phosphate acetyltransferase; Region: pta; TIGR00651
568709007079	hypothetical protein; Provisional; Region: PRK11588
568709007080	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
568709007081	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
568709007082	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
568709007083	PYR/PP interface [polypeptide binding]; other site
568709007084	dimer interface [polypeptide binding]; other site
568709007085	TPP binding site [chemical binding]; other site
568709007086	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
568709007087	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
568709007088	TPP-binding site [chemical binding]; other site
568709007089	dimer interface [polypeptide binding]; other site
568709007090	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
568709007091	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
568709007092	active site
568709007093	P-loop; other site
568709007094	phosphorylation site [posttranslational modification]
568709007095	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709007096	active site
568709007097	phosphorylation site [posttranslational modification]
568709007098	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568709007099	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709007100	DNA binding site [nucleotide binding]
568709007101	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
568709007102	putative dimerization interface [polypeptide binding]; other site
568709007103	putative ligand binding site [chemical binding]; other site
568709007104	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
568709007105	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
568709007106	nudix motif; other site
568709007107	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
568709007108	active site
568709007109	metal binding site [ion binding]; metal-binding site
568709007110	homotetramer interface [polypeptide binding]; other site
568709007111	glutathione S-transferase; Provisional; Region: PRK15113
568709007112	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
568709007113	C-terminal domain interface [polypeptide binding]; other site
568709007114	GSH binding site (G-site) [chemical binding]; other site
568709007115	dimer interface [polypeptide binding]; other site
568709007116	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
568709007117	N-terminal domain interface [polypeptide binding]; other site
568709007118	putative dimer interface [polypeptide binding]; other site
568709007119	putative substrate binding pocket (H-site) [chemical binding]; other site
568709007120	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
568709007121	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
568709007122	C-terminal domain interface [polypeptide binding]; other site
568709007123	GSH binding site (G-site) [chemical binding]; other site
568709007124	dimer interface [polypeptide binding]; other site
568709007125	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
568709007126	N-terminal domain interface [polypeptide binding]; other site
568709007127	putative dimer interface [polypeptide binding]; other site
568709007128	active site
568709007129	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
568709007130	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
568709007131	putative NAD(P) binding site [chemical binding]; other site
568709007132	putative active site [active]
568709007133	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
568709007134	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
568709007135	Walker A/P-loop; other site
568709007136	ATP binding site [chemical binding]; other site
568709007137	Q-loop/lid; other site
568709007138	ABC transporter signature motif; other site
568709007139	Walker B; other site
568709007140	D-loop; other site
568709007141	H-loop/switch region; other site
568709007142	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568709007143	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709007144	dimer interface [polypeptide binding]; other site
568709007145	conserved gate region; other site
568709007146	putative PBP binding loops; other site
568709007147	ABC-ATPase subunit interface; other site
568709007148	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
568709007149	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709007150	dimer interface [polypeptide binding]; other site
568709007151	conserved gate region; other site
568709007152	putative PBP binding loops; other site
568709007153	ABC-ATPase subunit interface; other site
568709007154	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
568709007155	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709007156	substrate binding pocket [chemical binding]; other site
568709007157	membrane-bound complex binding site; other site
568709007158	hinge residues; other site
568709007159	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
568709007160	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709007161	substrate binding pocket [chemical binding]; other site
568709007162	membrane-bound complex binding site; other site
568709007163	hinge residues; other site
568709007164	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
568709007165	Flavoprotein; Region: Flavoprotein; pfam02441
568709007166	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
568709007167	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
568709007168	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
568709007169	dimer interface [polypeptide binding]; other site
568709007170	active site
568709007171	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
568709007172	substrate binding site [chemical binding]; other site
568709007173	catalytic residue [active]
568709007174	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
568709007175	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
568709007176	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
568709007177	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
568709007178	catalytic residue [active]
568709007179	PAS fold; Region: PAS_4; pfam08448
568709007180	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
568709007181	putative active site [active]
568709007182	heme pocket [chemical binding]; other site
568709007183	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
568709007184	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709007185	Walker A motif; other site
568709007186	ATP binding site [chemical binding]; other site
568709007187	Walker B motif; other site
568709007188	arginine finger; other site
568709007189	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
568709007190	amidophosphoribosyltransferase; Provisional; Region: PRK09246
568709007191	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
568709007192	active site
568709007193	tetramer interface [polypeptide binding]; other site
568709007194	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568709007195	active site
568709007196	colicin V production protein; Provisional; Region: PRK10845
568709007197	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
568709007198	cell division protein DedD; Provisional; Region: PRK11633
568709007199	Sporulation related domain; Region: SPOR; pfam05036
568709007200	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
568709007201	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568709007202	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568709007203	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
568709007204	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
568709007205	hypothetical protein; Provisional; Region: PRK10847
568709007206	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
568709007207	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
568709007208	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
568709007209	dimerization interface 3.5A [polypeptide binding]; other site
568709007210	active site
568709007211	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
568709007212	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
568709007213	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
568709007214	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
568709007215	ligand binding site [chemical binding]; other site
568709007216	NAD binding site [chemical binding]; other site
568709007217	catalytic site [active]
568709007218	homodimer interface [polypeptide binding]; other site
568709007219	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
568709007220	putative transporter; Provisional; Region: PRK12382
568709007221	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709007222	putative substrate translocation pore; other site
568709007223	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709007224	non-specific DNA binding site [nucleotide binding]; other site
568709007225	salt bridge; other site
568709007226	sequence-specific DNA binding site [nucleotide binding]; other site
568709007227	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
568709007228	CAAX protease self-immunity; Region: Abi; pfam02517
568709007229	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
568709007230	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
568709007231	dimer interface [polypeptide binding]; other site
568709007232	active site
568709007233	Uncharacterized conserved protein [Function unknown]; Region: COG4121
568709007234	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
568709007235	YfcL protein; Region: YfcL; pfam08891
568709007236	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
568709007237	hypothetical protein; Provisional; Region: PRK10621
568709007238	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
568709007239	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
568709007240	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
568709007241	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
568709007242	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
568709007243	Tetramer interface [polypeptide binding]; other site
568709007244	active site
568709007245	FMN-binding site [chemical binding]; other site
568709007246	HemK family putative methylases; Region: hemK_fam; TIGR00536
568709007247	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709007248	S-adenosylmethionine binding site [chemical binding]; other site
568709007249	hypothetical protein; Provisional; Region: PRK04946
568709007250	Smr domain; Region: Smr; pfam01713
568709007251	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568709007252	catalytic core [active]
568709007253	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
568709007254	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
568709007255	substrate binding site [chemical binding]; other site
568709007256	oxyanion hole (OAH) forming residues; other site
568709007257	trimer interface [polypeptide binding]; other site
568709007258	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
568709007259	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
568709007260	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
568709007261	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
568709007262	dimer interface [polypeptide binding]; other site
568709007263	active site
568709007264	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
568709007265	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
568709007266	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
568709007267	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
568709007268	outer membrane protease; Reviewed; Region: PRK10993
568709007269	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
568709007270	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709007271	active site
568709007272	phosphorylation site [posttranslational modification]
568709007273	intermolecular recognition site; other site
568709007274	dimerization interface [polypeptide binding]; other site
568709007275	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
568709007276	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
568709007277	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
568709007278	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
568709007279	dimerization interface [polypeptide binding]; other site
568709007280	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709007281	dimer interface [polypeptide binding]; other site
568709007282	phosphorylation site [posttranslational modification]
568709007283	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709007284	ATP binding site [chemical binding]; other site
568709007285	Mg2+ binding site [ion binding]; other site
568709007286	G-X-G motif; other site
568709007287	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
568709007288	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
568709007289	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
568709007290	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709007291	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709007292	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
568709007293	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
568709007294	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
568709007295	putative acyl-acceptor binding pocket; other site
568709007296	aminotransferase; Validated; Region: PRK08175
568709007297	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709007298	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709007299	homodimer interface [polypeptide binding]; other site
568709007300	catalytic residue [active]
568709007301	glucokinase; Provisional; Region: glk; PRK00292
568709007302	glucokinase, proteobacterial type; Region: glk; TIGR00749
568709007303	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
568709007304	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
568709007305	Cl- selectivity filter; other site
568709007306	Cl- binding residues [ion binding]; other site
568709007307	pore gating glutamate residue; other site
568709007308	dimer interface [polypeptide binding]; other site
568709007309	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
568709007310	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
568709007311	dimer interface [polypeptide binding]; other site
568709007312	PYR/PP interface [polypeptide binding]; other site
568709007313	TPP binding site [chemical binding]; other site
568709007314	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568709007315	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
568709007316	TPP-binding site [chemical binding]; other site
568709007317	dimer interface [polypeptide binding]; other site
568709007318	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568709007319	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568709007320	active site
568709007321	catalytic tetrad [active]
568709007322	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
568709007323	manganese transport protein MntH; Reviewed; Region: PRK00701
568709007324	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
568709007325	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
568709007326	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
568709007327	Nucleoside recognition; Region: Gate; pfam07670
568709007328	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
568709007329	MASE1; Region: MASE1; pfam05231
568709007330	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
568709007331	diguanylate cyclase; Region: GGDEF; smart00267
568709007332	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709007333	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
568709007334	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
568709007335	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
568709007336	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
568709007337	active site
568709007338	HIGH motif; other site
568709007339	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
568709007340	active site
568709007341	KMSKS motif; other site
568709007342	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
568709007343	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709007344	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
568709007345	putative dimerization interface [polypeptide binding]; other site
568709007346	putative substrate binding pocket [chemical binding]; other site
568709007347	XapX domain; Region: XapX; TIGR03510
568709007348	nucleoside transporter; Region: 2A0110; TIGR00889
568709007349	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709007350	putative substrate translocation pore; other site
568709007351	purine nucleoside phosphorylase; Provisional; Region: PRK08202
568709007352	hypothetical protein; Provisional; Region: PRK11528
568709007353	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709007354	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709007355	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
568709007356	putative dimerization interface [polypeptide binding]; other site
568709007357	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
568709007358	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
568709007359	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
568709007360	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
568709007361	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
568709007362	nucleotide binding pocket [chemical binding]; other site
568709007363	K-X-D-G motif; other site
568709007364	catalytic site [active]
568709007365	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
568709007366	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
568709007367	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
568709007368	Dimer interface [polypeptide binding]; other site
568709007369	BRCT sequence motif; other site
568709007370	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
568709007371	cell division protein ZipA; Provisional; Region: PRK03427
568709007372	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
568709007373	FtsZ protein binding site [polypeptide binding]; other site
568709007374	putative sulfate transport protein CysZ; Validated; Region: PRK04949
568709007375	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
568709007376	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
568709007377	dimer interface [polypeptide binding]; other site
568709007378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709007379	catalytic residue [active]
568709007380	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
568709007381	dimerization domain swap beta strand [polypeptide binding]; other site
568709007382	regulatory protein interface [polypeptide binding]; other site
568709007383	active site
568709007384	regulatory phosphorylation site [posttranslational modification]; other site
568709007385	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
568709007386	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
568709007387	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
568709007388	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
568709007389	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
568709007390	HPr interaction site; other site
568709007391	glycerol kinase (GK) interaction site [polypeptide binding]; other site
568709007392	active site
568709007393	phosphorylation site [posttranslational modification]
568709007394	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
568709007395	dimer interface [polypeptide binding]; other site
568709007396	pyridoxamine kinase; Validated; Region: PRK05756
568709007397	pyridoxal binding site [chemical binding]; other site
568709007398	ATP binding site [chemical binding]; other site
568709007399	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
568709007400	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709007401	DNA-binding site [nucleotide binding]; DNA binding site
568709007402	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709007403	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709007404	homodimer interface [polypeptide binding]; other site
568709007405	catalytic residue [active]
568709007406	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
568709007407	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
568709007408	catalytic triad [active]
568709007409	hypothetical protein; Provisional; Region: PRK10318
568709007410	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
568709007411	Transglycosylase; Region: Transgly; cl17702
568709007412	cysteine synthase B; Region: cysM; TIGR01138
568709007413	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
568709007414	dimer interface [polypeptide binding]; other site
568709007415	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709007416	catalytic residue [active]
568709007417	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
568709007418	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
568709007419	Walker A/P-loop; other site
568709007420	ATP binding site [chemical binding]; other site
568709007421	Q-loop/lid; other site
568709007422	ABC transporter signature motif; other site
568709007423	Walker B; other site
568709007424	D-loop; other site
568709007425	H-loop/switch region; other site
568709007426	TOBE-like domain; Region: TOBE_3; pfam12857
568709007427	sulfate transport protein; Provisional; Region: cysT; CHL00187
568709007428	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709007429	dimer interface [polypeptide binding]; other site
568709007430	conserved gate region; other site
568709007431	putative PBP binding loops; other site
568709007432	ABC-ATPase subunit interface; other site
568709007433	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
568709007434	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709007435	dimer interface [polypeptide binding]; other site
568709007436	conserved gate region; other site
568709007437	putative PBP binding loops; other site
568709007438	ABC-ATPase subunit interface; other site
568709007439	thiosulfate transporter subunit; Provisional; Region: PRK10852
568709007440	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
568709007441	short chain dehydrogenase; Provisional; Region: PRK08226
568709007442	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
568709007443	NAD binding site [chemical binding]; other site
568709007444	homotetramer interface [polypeptide binding]; other site
568709007445	homodimer interface [polypeptide binding]; other site
568709007446	active site
568709007447	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
568709007448	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
568709007449	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
568709007450	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
568709007451	putative acetyltransferase; Provisional; Region: PRK03624
568709007452	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709007453	Coenzyme A binding pocket [chemical binding]; other site
568709007454	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
568709007455	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
568709007456	active site
568709007457	metal binding site [ion binding]; metal-binding site
568709007458	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
568709007459	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
568709007460	transcriptional regulator EutR; Provisional; Region: PRK10130
568709007461	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709007462	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709007463	carboxysome structural protein EutK; Provisional; Region: PRK15466
568709007464	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
568709007465	Hexamer interface [polypeptide binding]; other site
568709007466	Hexagonal pore residue; other site
568709007467	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
568709007468	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
568709007469	putative hexamer interface [polypeptide binding]; other site
568709007470	putative hexagonal pore; other site
568709007471	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
568709007472	putative hexamer interface [polypeptide binding]; other site
568709007473	putative hexagonal pore; other site
568709007474	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
568709007475	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
568709007476	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
568709007477	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
568709007478	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
568709007479	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
568709007480	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
568709007481	active site
568709007482	metal binding site [ion binding]; metal-binding site
568709007483	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
568709007484	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568709007485	nucleotide binding site [chemical binding]; other site
568709007486	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
568709007487	putative catalytic cysteine [active]
568709007488	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
568709007489	Hexamer/Pentamer interface [polypeptide binding]; other site
568709007490	central pore; other site
568709007491	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
568709007492	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
568709007493	Hexamer interface [polypeptide binding]; other site
568709007494	Putative hexagonal pore residue; other site
568709007495	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
568709007496	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
568709007497	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
568709007498	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
568709007499	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
568709007500	G1 box; other site
568709007501	GTP/Mg2+ binding site [chemical binding]; other site
568709007502	G2 box; other site
568709007503	Switch I region; other site
568709007504	G3 box; other site
568709007505	Switch II region; other site
568709007506	G4 box; other site
568709007507	G5 box; other site
568709007508	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
568709007509	putative hexamer interface [polypeptide binding]; other site
568709007510	putative hexagonal pore; other site
568709007511	Transposase IS200 like; Region: Y1_Tnp; pfam01797
568709007512	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
568709007513	Malic enzyme, N-terminal domain; Region: malic; pfam00390
568709007514	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
568709007515	putative NAD(P) binding site [chemical binding]; other site
568709007516	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
568709007517	transaldolase-like protein; Provisional; Region: PTZ00411
568709007518	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
568709007519	active site
568709007520	dimer interface [polypeptide binding]; other site
568709007521	catalytic residue [active]
568709007522	transketolase; Reviewed; Region: PRK12753
568709007523	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
568709007524	TPP-binding site [chemical binding]; other site
568709007525	dimer interface [polypeptide binding]; other site
568709007526	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
568709007527	PYR/PP interface [polypeptide binding]; other site
568709007528	dimer interface [polypeptide binding]; other site
568709007529	TPP binding site [chemical binding]; other site
568709007530	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
568709007531	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
568709007532	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
568709007533	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
568709007534	dimer interface [polypeptide binding]; other site
568709007535	ADP-ribose binding site [chemical binding]; other site
568709007536	active site
568709007537	nudix motif; other site
568709007538	metal binding site [ion binding]; metal-binding site
568709007539	putative periplasmic esterase; Provisional; Region: PRK03642
568709007540	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
568709007541	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
568709007542	4Fe-4S binding domain; Region: Fer4; pfam00037
568709007543	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
568709007544	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709007545	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
568709007546	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
568709007547	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709007548	dimerization interface [polypeptide binding]; other site
568709007549	Histidine kinase; Region: HisKA_3; pfam07730
568709007550	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709007551	ATP binding site [chemical binding]; other site
568709007552	Mg2+ binding site [ion binding]; other site
568709007553	G-X-G motif; other site
568709007554	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
568709007555	Protein export membrane protein; Region: SecD_SecF; cl14618
568709007556	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
568709007557	ArsC family; Region: ArsC; pfam03960
568709007558	putative catalytic residues [active]
568709007559	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
568709007560	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
568709007561	metal binding site [ion binding]; metal-binding site
568709007562	dimer interface [polypeptide binding]; other site
568709007563	hypothetical protein; Provisional; Region: PRK13664
568709007564	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
568709007565	Helicase; Region: Helicase_RecD; pfam05127
568709007566	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
568709007567	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
568709007568	Predicted metalloprotease [General function prediction only]; Region: COG2321
568709007569	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
568709007570	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
568709007571	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
568709007572	ATP binding site [chemical binding]; other site
568709007573	active site
568709007574	substrate binding site [chemical binding]; other site
568709007575	lipoprotein; Provisional; Region: PRK11679
568709007576	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
568709007577	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
568709007578	dihydrodipicolinate synthase; Region: dapA; TIGR00674
568709007579	dimer interface [polypeptide binding]; other site
568709007580	active site
568709007581	catalytic residue [active]
568709007582	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
568709007583	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
568709007584	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
568709007585	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
568709007586	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
568709007587	catalytic triad [active]
568709007588	Glycerate kinase family; Region: Gly_kinase; cl00841
568709007589	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
568709007590	Domain of unknown function DUF20; Region: UPF0118; pfam01594
568709007591	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
568709007592	Peptidase family M48; Region: Peptidase_M48; cl12018
568709007593	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
568709007594	ArsC family; Region: ArsC; pfam03960
568709007595	catalytic residues [active]
568709007596	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
568709007597	DNA replication initiation factor; Provisional; Region: PRK08084
568709007598	uracil transporter; Provisional; Region: PRK10720
568709007599	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568709007600	active site
568709007601	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
568709007602	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
568709007603	dimerization interface [polypeptide binding]; other site
568709007604	putative ATP binding site [chemical binding]; other site
568709007605	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
568709007606	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
568709007607	active site
568709007608	substrate binding site [chemical binding]; other site
568709007609	cosubstrate binding site; other site
568709007610	catalytic site [active]
568709007611	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
568709007612	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
568709007613	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
568709007614	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
568709007615	putative active site [active]
568709007616	catalytic site [active]
568709007617	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
568709007618	domain interface [polypeptide binding]; other site
568709007619	active site
568709007620	catalytic site [active]
568709007621	exopolyphosphatase; Provisional; Region: PRK10854
568709007622	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568709007623	nucleotide binding site [chemical binding]; other site
568709007624	MASE1; Region: MASE1; pfam05231
568709007625	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
568709007626	diguanylate cyclase; Region: GGDEF; smart00267
568709007627	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709007628	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
568709007629	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
568709007630	Integrase core domain; Region: rve; pfam00665
568709007631	GMP synthase; Reviewed; Region: guaA; PRK00074
568709007632	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
568709007633	AMP/PPi binding site [chemical binding]; other site
568709007634	candidate oxyanion hole; other site
568709007635	catalytic triad [active]
568709007636	potential glutamine specificity residues [chemical binding]; other site
568709007637	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
568709007638	ATP Binding subdomain [chemical binding]; other site
568709007639	Ligand Binding sites [chemical binding]; other site
568709007640	Dimerization subdomain; other site
568709007641	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
568709007642	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
568709007643	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
568709007644	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
568709007645	active site
568709007646	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
568709007647	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
568709007648	generic binding surface II; other site
568709007649	generic binding surface I; other site
568709007650	AIDA autotransporter-like protein ShdA; Provisional; Region: PRK15319
568709007651	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
568709007652	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
568709007653	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
568709007654	Autotransporter beta-domain; Region: Autotransporter; smart00869
568709007655	outer membrane protein RatB; Provisional; Region: PRK15314
568709007656	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007657	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007658	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007659	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007660	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007661	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007662	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007663	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007664	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007665	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007666	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007667	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007668	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007669	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007670	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007671	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007672	outer membrane protein RatA; Provisional; Region: PRK15315
568709007673	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007674	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007675	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007676	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007677	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007678	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007679	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007680	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007681	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007682	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
568709007683	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
568709007684	intimin-like protein SinH; Provisional; Region: PRK15318
568709007685	intimin-like protein SinH; Provisional; Region: PRK15318
568709007686	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
568709007687	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
568709007688	GTP-binding protein Der; Reviewed; Region: PRK00093
568709007689	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
568709007690	G1 box; other site
568709007691	GTP/Mg2+ binding site [chemical binding]; other site
568709007692	Switch I region; other site
568709007693	G2 box; other site
568709007694	Switch II region; other site
568709007695	G3 box; other site
568709007696	G4 box; other site
568709007697	G5 box; other site
568709007698	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
568709007699	G1 box; other site
568709007700	GTP/Mg2+ binding site [chemical binding]; other site
568709007701	Switch I region; other site
568709007702	G2 box; other site
568709007703	G3 box; other site
568709007704	Switch II region; other site
568709007705	G4 box; other site
568709007706	G5 box; other site
568709007707	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
568709007708	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
568709007709	Trp docking motif [polypeptide binding]; other site
568709007710	active site
568709007711	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
568709007712	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
568709007713	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
568709007714	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
568709007715	dimer interface [polypeptide binding]; other site
568709007716	motif 1; other site
568709007717	active site
568709007718	motif 2; other site
568709007719	motif 3; other site
568709007720	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
568709007721	anticodon binding site; other site
568709007722	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
568709007723	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
568709007724	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
568709007725	cytoskeletal protein RodZ; Provisional; Region: PRK10856
568709007726	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709007727	non-specific DNA binding site [nucleotide binding]; other site
568709007728	salt bridge; other site
568709007729	sequence-specific DNA binding site [nucleotide binding]; other site
568709007730	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
568709007731	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
568709007732	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709007733	FeS/SAM binding site; other site
568709007734	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
568709007735	active site
568709007736	multimer interface [polypeptide binding]; other site
568709007737	4Fe-4S binding domain; Region: Fer4; pfam00037
568709007738	hydrogenase 4 subunit H; Validated; Region: PRK08222
568709007739	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
568709007740	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
568709007741	4Fe-4S binding domain; Region: Fer4; pfam00037
568709007743	penicillin-binding protein 1C; Provisional; Region: PRK11240
568709007744	Transglycosylase; Region: Transgly; pfam00912
568709007745	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
568709007746	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
568709007747	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
568709007748	MG2 domain; Region: A2M_N; pfam01835
568709007749	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
568709007750	surface patch; other site
568709007751	thioester region; other site
568709007752	specificity defining residues; other site
568709007753	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
568709007754	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
568709007755	active site residue [active]
568709007756	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
568709007757	active site residue [active]
568709007758	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
568709007759	aminopeptidase B; Provisional; Region: PRK05015
568709007760	Peptidase; Region: DUF3663; pfam12404
568709007761	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
568709007762	interface (dimer of trimers) [polypeptide binding]; other site
568709007763	Substrate-binding/catalytic site; other site
568709007764	Zn-binding sites [ion binding]; other site
568709007765	hypothetical protein; Provisional; Region: PRK10721
568709007766	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
568709007767	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
568709007768	catalytic loop [active]
568709007769	iron binding site [ion binding]; other site
568709007770	chaperone protein HscA; Provisional; Region: hscA; PRK05183
568709007771	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
568709007772	nucleotide binding site [chemical binding]; other site
568709007773	putative NEF/HSP70 interaction site [polypeptide binding]; other site
568709007774	SBD interface [polypeptide binding]; other site
568709007775	co-chaperone HscB; Provisional; Region: hscB; PRK05014
568709007776	DnaJ domain; Region: DnaJ; pfam00226
568709007777	HSP70 interaction site [polypeptide binding]; other site
568709007778	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
568709007779	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
568709007780	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
568709007781	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
568709007782	trimerization site [polypeptide binding]; other site
568709007783	active site
568709007784	cysteine desulfurase; Provisional; Region: PRK14012
568709007785	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
568709007786	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568709007787	catalytic residue [active]
568709007788	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
568709007789	Rrf2 family protein; Region: rrf2_super; TIGR00738
568709007790	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
568709007791	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
568709007792	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
568709007793	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
568709007794	active site
568709007795	dimerization interface [polypeptide binding]; other site
568709007796	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
568709007797	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
568709007798	sulfite reductase, subunit A; Region: sulfite_red_A; TIGR02910
568709007799	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
568709007800	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
568709007801	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
568709007802	FAD binding pocket [chemical binding]; other site
568709007803	FAD binding motif [chemical binding]; other site
568709007804	phosphate binding motif [ion binding]; other site
568709007805	beta-alpha-beta structure motif; other site
568709007806	NAD binding pocket [chemical binding]; other site
568709007807	Iron coordination center [ion binding]; other site
568709007808	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
568709007809	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
568709007810	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
568709007811	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
568709007812	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
568709007813	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
568709007814	PRD domain; Region: PRD; pfam00874
568709007815	PRD domain; Region: PRD; pfam00874
568709007816	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
568709007817	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709007818	putative substrate translocation pore; other site
568709007819	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
568709007820	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
568709007821	dimer interface [polypeptide binding]; other site
568709007822	active site
568709007823	glycine-pyridoxal phosphate binding site [chemical binding]; other site
568709007824	folate binding site [chemical binding]; other site
568709007825	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
568709007826	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
568709007827	heme-binding site [chemical binding]; other site
568709007828	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
568709007829	FAD binding pocket [chemical binding]; other site
568709007830	FAD binding motif [chemical binding]; other site
568709007831	phosphate binding motif [ion binding]; other site
568709007832	beta-alpha-beta structure motif; other site
568709007833	NAD binding pocket [chemical binding]; other site
568709007834	Heme binding  pocket [chemical binding]; other site
568709007835	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
568709007836	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709007837	DNA binding site [nucleotide binding]
568709007838	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
568709007839	lysine decarboxylase CadA; Provisional; Region: PRK15400
568709007840	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
568709007841	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
568709007842	homodimer interface [polypeptide binding]; other site
568709007843	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709007844	catalytic residue [active]
568709007845	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
568709007846	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
568709007847	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709007848	putative substrate translocation pore; other site
568709007849	POT family; Region: PTR2; pfam00854
568709007850	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
568709007851	Nitrogen regulatory protein P-II; Region: P-II; smart00938
568709007852	response regulator GlrR; Provisional; Region: PRK15115
568709007853	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709007854	active site
568709007855	phosphorylation site [posttranslational modification]
568709007856	intermolecular recognition site; other site
568709007857	dimerization interface [polypeptide binding]; other site
568709007858	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709007859	Walker A motif; other site
568709007860	ATP binding site [chemical binding]; other site
568709007861	Walker B motif; other site
568709007862	arginine finger; other site
568709007863	hypothetical protein; Provisional; Region: PRK10722
568709007864	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568709007865	HAMP domain; Region: HAMP; pfam00672
568709007866	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709007867	dimer interface [polypeptide binding]; other site
568709007868	phosphorylation site [posttranslational modification]
568709007869	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709007870	ATP binding site [chemical binding]; other site
568709007871	Mg2+ binding site [ion binding]; other site
568709007872	G-X-G motif; other site
568709007873	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
568709007874	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
568709007875	dimerization interface [polypeptide binding]; other site
568709007876	ATP binding site [chemical binding]; other site
568709007877	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
568709007878	dimerization interface [polypeptide binding]; other site
568709007879	ATP binding site [chemical binding]; other site
568709007880	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
568709007881	putative active site [active]
568709007882	catalytic triad [active]
568709007883	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
568709007884	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709007885	substrate binding pocket [chemical binding]; other site
568709007886	membrane-bound complex binding site; other site
568709007887	hinge residues; other site
568709007888	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
568709007889	N-acetyl-D-glucosamine binding site [chemical binding]; other site
568709007890	catalytic residue [active]
568709007891	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
568709007892	nucleoside/Zn binding site; other site
568709007893	dimer interface [polypeptide binding]; other site
568709007894	catalytic motif [active]
568709007895	hypothetical protein; Provisional; Region: PRK11590
568709007896	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
568709007897	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
568709007898	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568709007899	active site turn [active]
568709007900	phosphorylation site [posttranslational modification]
568709007901	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568709007902	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
568709007903	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
568709007904	putative active site [active]
568709007905	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568709007906	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
568709007907	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568709007908	putative active site [active]
568709007909	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
568709007910	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
568709007911	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
568709007912	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
568709007913	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709007914	putative substrate translocation pore; other site
568709007915	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709007916	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709007917	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568709007918	dimerization interface [polypeptide binding]; other site
568709007919	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
568709007920	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
568709007921	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
568709007922	active site
568709007923	hydrophilic channel; other site
568709007924	dimerization interface [polypeptide binding]; other site
568709007925	catalytic residues [active]
568709007926	active site lid [active]
568709007927	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
568709007928	Recombination protein O N terminal; Region: RecO_N; pfam11967
568709007929	Recombination protein O C terminal; Region: RecO_C; pfam02565
568709007930	GTPase Era; Reviewed; Region: era; PRK00089
568709007931	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
568709007932	G1 box; other site
568709007933	GTP/Mg2+ binding site [chemical binding]; other site
568709007934	Switch I region; other site
568709007935	G2 box; other site
568709007936	Switch II region; other site
568709007937	G3 box; other site
568709007938	G4 box; other site
568709007939	G5 box; other site
568709007940	KH domain; Region: KH_2; pfam07650
568709007941	ribonuclease III; Reviewed; Region: rnc; PRK00102
568709007942	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
568709007943	dimerization interface [polypeptide binding]; other site
568709007944	active site
568709007945	metal binding site [ion binding]; metal-binding site
568709007946	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
568709007947	dsRNA binding site [nucleotide binding]; other site
568709007948	signal peptidase I; Provisional; Region: PRK10861
568709007949	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
568709007950	Catalytic site [active]
568709007951	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
568709007952	GTP-binding protein LepA; Provisional; Region: PRK05433
568709007953	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
568709007954	G1 box; other site
568709007955	putative GEF interaction site [polypeptide binding]; other site
568709007956	GTP/Mg2+ binding site [chemical binding]; other site
568709007957	Switch I region; other site
568709007958	G2 box; other site
568709007959	G3 box; other site
568709007960	Switch II region; other site
568709007961	G4 box; other site
568709007962	G5 box; other site
568709007963	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
568709007964	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
568709007965	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
568709007966	type III secretion protein GogB; Provisional; Region: PRK15386
568709007967	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
568709007968	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
568709007969	Macro domain, Appr-1"-pase family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Appr_pase; cd02900
568709007970	ADP-ribose binding site [chemical binding]; other site
568709007971	putative active site [active]
568709007972	dimer interface [polypeptide binding]; other site
568709007973	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
568709007974	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
568709007975	Phage Tail Collar Domain; Region: Collar; pfam07484
568709007976	Phage-related protein, tail component [Function unknown]; Region: COG4733
568709007977	Putative phage tail protein; Region: Phage-tail_3; pfam13550
568709007978	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
568709007979	Interdomain contacts; other site
568709007980	Cytokine receptor motif; other site
568709007981	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
568709007982	Fibronectin type III protein; Region: DUF3672; pfam12421
568709007983	Phage-related protein, tail component [Function unknown]; Region: COG4723
568709007985	Phage-related protein [Function unknown]; Region: gp18; COG4672
568709007986	Phage-related protein [Function unknown]; Region: COG4718
568709007987	Phage-related minor tail protein [Function unknown]; Region: COG5281
568709007988	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
568709007989	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
568709007990	Minor tail protein T; Region: Phage_tail_T; pfam06223
568709007991	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
568709007992	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
568709007993	Phage tail protein; Region: Phage_tail_3; pfam08813
568709007994	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
568709007995	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
568709007996	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
568709007997	Probable transposase; Region: OrfB_IS605; pfam01385
568709007998	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
568709007999	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
568709008000	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; cl05094
568709008001	DNA packaging protein FI; Region: Packaging_FI; pfam14000
568709008002	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
568709008003	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
568709008004	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
568709008005	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
568709008006	tandem repeat interface [polypeptide binding]; other site
568709008007	oligomer interface [polypeptide binding]; other site
568709008008	active site residues [active]
568709008009	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
568709008010	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
568709008011	gpW; Region: gpW; pfam02831
568709008012	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
568709008013	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
568709008014	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
568709008015	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
568709008016	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
568709008017	catalytic residues [active]
568709008018	PipA protein; Region: PipA; pfam07108
568709008019	ORF6N domain; Region: ORF6N; pfam10543
568709008020	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
568709008021	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
568709008022	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
568709008024	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
568709008025	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
568709008026	integrase; Provisional; Region: PRK09692
568709008027	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
568709008028	active site
568709008029	Int/Topo IB signature motif; other site
568709008030	SoxR reducing system protein RseC; Provisional; Region: PRK10862
568709008031	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
568709008032	anti-sigma E factor; Provisional; Region: rseB; PRK09455
568709008033	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
568709008034	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
568709008035	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
568709008036	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
568709008037	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
568709008038	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
568709008039	DNA binding residues [nucleotide binding]
568709008040	L-aspartate oxidase; Provisional; Region: PRK09077
568709008041	L-aspartate oxidase; Provisional; Region: PRK06175
568709008042	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
568709008043	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
568709008044	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709008045	S-adenosylmethionine binding site [chemical binding]; other site
568709008046	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
568709008047	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
568709008048	ATP binding site [chemical binding]; other site
568709008049	Mg++ binding site [ion binding]; other site
568709008050	motif III; other site
568709008051	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709008052	nucleotide binding region [chemical binding]; other site
568709008053	ATP-binding site [chemical binding]; other site
568709008054	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709008055	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709008056	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568709008057	dimerization interface [polypeptide binding]; other site
568709008058	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
568709008059	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
568709008060	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
568709008061	ligand binding site [chemical binding]; other site
568709008062	active site
568709008063	UGI interface [polypeptide binding]; other site
568709008064	catalytic site [active]
568709008065	putative methyltransferase; Provisional; Region: PRK10864
568709008066	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
568709008067	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
568709008068	thioredoxin 2; Provisional; Region: PRK10996
568709008069	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
568709008070	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
568709008071	catalytic residues [active]
568709008072	Uncharacterized conserved protein [Function unknown]; Region: COG3148
568709008073	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
568709008074	CoA binding domain; Region: CoA_binding_2; pfam13380
568709008075	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
568709008076	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
568709008077	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
568709008078	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709008079	Coenzyme A binding pocket [chemical binding]; other site
568709008080	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
568709008081	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
568709008082	domain interface [polypeptide binding]; other site
568709008083	putative active site [active]
568709008084	catalytic site [active]
568709008085	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
568709008086	domain interface [polypeptide binding]; other site
568709008087	putative active site [active]
568709008088	catalytic site [active]
568709008089	lipoprotein; Provisional; Region: PRK10759
568709008090	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
568709008091	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709008092	putative substrate translocation pore; other site
568709008093	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
568709008094	protein disaggregation chaperone; Provisional; Region: PRK10865
568709008095	Clp amino terminal domain; Region: Clp_N; pfam02861
568709008096	Clp amino terminal domain; Region: Clp_N; pfam02861
568709008097	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709008098	Walker A motif; other site
568709008099	ATP binding site [chemical binding]; other site
568709008100	Walker B motif; other site
568709008101	arginine finger; other site
568709008102	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709008103	Walker A motif; other site
568709008104	ATP binding site [chemical binding]; other site
568709008105	Walker B motif; other site
568709008106	arginine finger; other site
568709008107	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
568709008108	hypothetical protein; Provisional; Region: PRK10723
568709008109	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
568709008110	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
568709008111	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568709008112	RNA binding surface [nucleotide binding]; other site
568709008113	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
568709008114	active site
568709008115	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
568709008116	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
568709008117	30S subunit binding site; other site
568709008118	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
568709008119	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
568709008120	Prephenate dehydratase; Region: PDT; pfam00800
568709008121	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
568709008122	putative L-Phe binding site [chemical binding]; other site
568709008123	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
568709008124	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
568709008125	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
568709008126	prephenate dehydrogenase; Validated; Region: PRK08507
568709008127	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
568709008128	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
568709008129	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
568709008130	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
568709008131	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568709008132	metal binding site [ion binding]; metal-binding site
568709008133	active site
568709008134	I-site; other site
568709008137	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
568709008138	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
568709008139	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
568709008140	RimM N-terminal domain; Region: RimM; pfam01782
568709008141	PRC-barrel domain; Region: PRC; pfam05239
568709008142	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
568709008143	signal recognition particle protein; Provisional; Region: PRK10867
568709008144	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
568709008145	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
568709008146	P loop; other site
568709008147	GTP binding site [chemical binding]; other site
568709008148	Signal peptide binding domain; Region: SRP_SPB; pfam02978
568709008149	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
568709008150	hypothetical protein; Provisional; Region: PRK11573
568709008151	Domain of unknown function DUF21; Region: DUF21; pfam01595
568709008152	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
568709008153	Transporter associated domain; Region: CorC_HlyC; smart01091
568709008154	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
568709008155	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
568709008156	dimer interface [polypeptide binding]; other site
568709008157	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
568709008158	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
568709008159	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
568709008160	recombination and repair protein; Provisional; Region: PRK10869
568709008161	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
568709008162	Walker A/P-loop; other site
568709008163	ATP binding site [chemical binding]; other site
568709008164	Q-loop/lid; other site
568709008165	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
568709008166	ABC transporter signature motif; other site
568709008167	Walker B; other site
568709008168	D-loop; other site
568709008169	H-loop/switch region; other site
568709008170	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
568709008171	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
568709008172	hypothetical protein; Validated; Region: PRK01777
568709008173	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
568709008174	putative coenzyme Q binding site [chemical binding]; other site
568709008175	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
568709008176	SmpB-tmRNA interface; other site
568709008177	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008178	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008179	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008180	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008181	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008182	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008183	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008184	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008185	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008186	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008187	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008188	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
568709008189	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008190	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008191	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
568709008192	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008193	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709008194	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
568709008195	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
568709008197	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
568709008198	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709008203	integrase; Provisional; Region: PRK09692
568709008204	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
568709008205	active site
568709008206	Int/Topo IB signature motif; other site
568709008207	SEC-C motif; Region: SEC-C; pfam02810
568709008208	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
568709008209	Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG5519
568709008210	Predicted ATP-binding protein involved in virulence [General function prediction only]; Region: COG3950
568709008211	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568709008212	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709008213	non-specific DNA binding site [nucleotide binding]; other site
568709008214	salt bridge; other site
568709008215	sequence-specific DNA binding site [nucleotide binding]; other site
568709008216	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
568709008217	Phosphotransferase system sorbitol-specific component IIC [Carbohydrate transport and metabolism]; Region: SrlA; COG3730
568709008218	Phosphotransferase system sorbitol-specific component IIA [Carbohydrate transport and metabolism]; Region: SrlB; COG3731
568709008219	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
568709008220	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
568709008221	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
568709008222	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568709008223	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568709008224	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
568709008225	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
568709008226	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
568709008227	active site
568709008228	dimer interface [polypeptide binding]; other site
568709008229	magnesium binding site [ion binding]; other site
568709008230	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
568709008231	tetramer interface [polypeptide binding]; other site
568709008232	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568709008233	active site
568709008234	Thermophilic glucose-6-phosphate isomerase and related metalloenzymes [Carbohydrate transport and metabolism / General function prediction only]; Region: COG2140
568709008235	Glucose-6-phosphate isomerase (GPI); Region: GPI; pfam06560
568709008237	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
568709008238	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
568709008239	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
568709008240	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
568709008241	Integrase; Region: Integrase_1; pfam12835
568709008244	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
568709008245	DNA-binding interface [nucleotide binding]; DNA binding site
568709008246	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3972
568709008247	Family description; Region: UvrD_C_2; pfam13538
568709008248	Transposase; Region: HTH_Tnp_1; cl17663
568709008249	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
568709008250	putative transposase OrfB; Reviewed; Region: PHA02517
568709008251	HTH-like domain; Region: HTH_21; pfam13276
568709008252	Integrase core domain; Region: rve; pfam00665
568709008253	Integrase core domain; Region: rve_2; pfam13333
568709008254	Repressor of phase-1 flagellin; Region: Flag1_repress; pfam03614
568709008255	flagellin; Validated; Region: PRK08026
568709008256	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
568709008257	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
568709008258	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
568709008259	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
568709008260	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
568709008261	catalytic residues [active]
568709008262	catalytic nucleophile [active]
568709008263	Presynaptic Site I dimer interface [polypeptide binding]; other site
568709008264	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
568709008265	Synaptic Flat tetramer interface [polypeptide binding]; other site
568709008266	Synaptic Site I dimer interface [polypeptide binding]; other site
568709008267	DNA binding site [nucleotide binding]
568709008268	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
568709008269	DNA-binding interface [nucleotide binding]; DNA binding site
568709008270	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
568709008271	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
568709008272	homodimer interface [polypeptide binding]; other site
568709008273	active site
568709008274	TDP-binding site; other site
568709008275	acceptor substrate-binding pocket; other site
568709008276	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568709008277	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709008278	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
568709008279	Walker A/P-loop; other site
568709008280	ATP binding site [chemical binding]; other site
568709008281	Q-loop/lid; other site
568709008282	ABC transporter signature motif; other site
568709008283	Walker B; other site
568709008284	D-loop; other site
568709008285	H-loop/switch region; other site
568709008286	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
568709008287	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
568709008288	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709008289	Walker A/P-loop; other site
568709008290	ATP binding site [chemical binding]; other site
568709008291	Q-loop/lid; other site
568709008292	ABC transporter signature motif; other site
568709008293	Walker B; other site
568709008294	D-loop; other site
568709008295	H-loop/switch region; other site
568709008296	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
568709008297	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
568709008298	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
568709008299	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
568709008300	outer membrane receptor FepA; Provisional; Region: PRK13528
568709008301	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
568709008302	N-terminal plug; other site
568709008303	ligand-binding site [chemical binding]; other site
568709008304	secreted effector protein PipB2; Provisional; Region: PRK15196
568709008305	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
568709008306	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
568709008307	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
568709008308	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
568709008309	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
568709008310	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
568709008311	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
568709008312	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
568709008313	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
568709008314	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
568709008315	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
568709008316	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
568709008317	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709008318	dimer interface [polypeptide binding]; other site
568709008319	phosphorylation site [posttranslational modification]
568709008320	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709008321	ATP binding site [chemical binding]; other site
568709008322	Mg2+ binding site [ion binding]; other site
568709008323	G-X-G motif; other site
568709008324	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
568709008325	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709008326	active site
568709008327	phosphorylation site [posttranslational modification]
568709008328	intermolecular recognition site; other site
568709008329	dimerization interface [polypeptide binding]; other site
568709008330	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709008331	DNA binding site [nucleotide binding]
568709008332	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
568709008333	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
568709008334	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
568709008335	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
568709008336	substrate binding pocket [chemical binding]; other site
568709008337	active site
568709008338	iron coordination sites [ion binding]; other site
568709008339	Predicted dehydrogenase [General function prediction only]; Region: COG0579
568709008340	hydroxyglutarate oxidase; Provisional; Region: PRK11728
568709008341	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
568709008342	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
568709008343	tetramerization interface [polypeptide binding]; other site
568709008344	NAD(P) binding site [chemical binding]; other site
568709008345	catalytic residues [active]
568709008346	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
568709008347	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
568709008348	inhibitor-cofactor binding pocket; inhibition site
568709008349	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709008350	catalytic residue [active]
568709008351	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
568709008352	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
568709008353	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709008354	DNA-binding site [nucleotide binding]; DNA binding site
568709008355	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
568709008356	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
568709008357	bacterial OsmY and nodulation domain; Region: BON; smart00749
568709008358	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568709008359	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
568709008360	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568709008361	dimerization interface [polypeptide binding]; other site
568709008362	putative DNA binding site [nucleotide binding]; other site
568709008363	Transcriptional regulators [Transcription]; Region: MarR; COG1846
568709008364	putative Zn2+ binding site [ion binding]; other site
568709008365	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
568709008366	active site residue [active]
568709008367	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
568709008368	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
568709008369	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
568709008370	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
568709008371	hypothetical protein; Provisional; Region: PRK10556
568709008372	hypothetical protein; Provisional; Region: PRK10132
568709008373	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
568709008374	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709008375	DNA-binding site [nucleotide binding]; DNA binding site
568709008376	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709008377	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709008378	homodimer interface [polypeptide binding]; other site
568709008379	catalytic residue [active]
568709008380	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
568709008381	Uncharacterized conserved protein [Function unknown]; Region: COG2128
568709008382	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
568709008383	catalytic residues [active]
568709008384	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
568709008385	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
568709008386	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
568709008387	Class I ribonucleotide reductase; Region: RNR_I; cd01679
568709008388	active site
568709008389	dimer interface [polypeptide binding]; other site
568709008390	catalytic residues [active]
568709008391	effector binding site; other site
568709008392	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
568709008393	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
568709008394	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
568709008395	dimer interface [polypeptide binding]; other site
568709008396	putative radical transfer pathway; other site
568709008397	diiron center [ion binding]; other site
568709008398	tyrosyl radical; other site
568709008399	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
568709008400	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
568709008401	Walker A/P-loop; other site
568709008402	ATP binding site [chemical binding]; other site
568709008403	Q-loop/lid; other site
568709008404	ABC transporter signature motif; other site
568709008405	Walker B; other site
568709008406	D-loop; other site
568709008407	H-loop/switch region; other site
568709008408	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
568709008409	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
568709008410	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709008411	dimer interface [polypeptide binding]; other site
568709008412	conserved gate region; other site
568709008413	putative PBP binding loops; other site
568709008414	ABC-ATPase subunit interface; other site
568709008415	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
568709008416	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
568709008417	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
568709008418	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709008419	transcriptional repressor MprA; Provisional; Region: PRK10870
568709008420	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
568709008421	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
568709008422	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
568709008423	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709008424	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
568709008425	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709008426	putative substrate translocation pore; other site
568709008427	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709008428	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
568709008429	S-ribosylhomocysteinase; Provisional; Region: PRK02260
568709008430	glutamate--cysteine ligase; Provisional; Region: PRK02107
568709008431	Predicted membrane protein [Function unknown]; Region: COG1238
568709008432	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
568709008433	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709008434	motif II; other site
568709008435	carbon storage regulator; Provisional; Region: PRK01712
568709008436	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
568709008437	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
568709008438	motif 1; other site
568709008439	active site
568709008440	motif 2; other site
568709008441	motif 3; other site
568709008442	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
568709008443	DHHA1 domain; Region: DHHA1; pfam02272
568709008444	recombination regulator RecX; Reviewed; Region: recX; PRK00117
568709008445	recombinase A; Provisional; Region: recA; PRK09354
568709008446	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
568709008447	hexamer interface [polypeptide binding]; other site
568709008448	Walker A motif; other site
568709008449	ATP binding site [chemical binding]; other site
568709008450	Walker B motif; other site
568709008451	hypothetical protein; Validated; Region: PRK03661
568709008452	Transglycosylase SLT domain; Region: SLT_2; pfam13406
568709008453	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
568709008454	N-acetyl-D-glucosamine binding site [chemical binding]; other site
568709008455	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
568709008456	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
568709008457	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
568709008458	Nucleoside recognition; Region: Gate; pfam07670
568709008459	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
568709008460	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
568709008461	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
568709008462	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
568709008463	putative NAD(P) binding site [chemical binding]; other site
568709008464	active site
568709008465	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
568709008466	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
568709008467	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
568709008468	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709008469	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
568709008470	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
568709008471	putative active site [active]
568709008472	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
568709008473	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
568709008474	GAF domain; Region: GAF; pfam01590
568709008475	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709008476	Walker A motif; other site
568709008477	ATP binding site [chemical binding]; other site
568709008478	Walker B motif; other site
568709008479	arginine finger; other site
568709008480	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
568709008481	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
568709008482	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
568709008483	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
568709008484	iron binding site [ion binding]; other site
568709008485	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
568709008486	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568709008487	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709008488	Acylphosphatase; Region: Acylphosphatase; pfam00708
568709008489	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
568709008490	HypF finger; Region: zf-HYPF; pfam07503
568709008491	HypF finger; Region: zf-HYPF; pfam07503
568709008492	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
568709008493	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
568709008494	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
568709008495	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
568709008496	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
568709008497	nickel binding site [ion binding]; other site
568709008498	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
568709008499	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
568709008500	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
568709008501	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
568709008502	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
568709008503	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
568709008504	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
568709008505	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
568709008506	NADH dehydrogenase; Region: NADHdh; cl00469
568709008507	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
568709008508	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
568709008509	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
568709008510	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
568709008511	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
568709008512	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
568709008513	hydrogenase assembly chaperone; Provisional; Region: PRK10409
568709008514	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
568709008515	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
568709008516	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
568709008517	dimerization interface [polypeptide binding]; other site
568709008518	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
568709008519	ATP binding site [chemical binding]; other site
568709008520	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
568709008521	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
568709008522	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
568709008523	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709008524	Walker A motif; other site
568709008525	ATP binding site [chemical binding]; other site
568709008526	Walker B motif; other site
568709008527	arginine finger; other site
568709008528	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
568709008529	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
568709008530	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
568709008531	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
568709008532	metal binding site [ion binding]; metal-binding site
568709008533	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
568709008534	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
568709008535	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
568709008536	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
568709008537	ABC-ATPase subunit  interface; other site
568709008538	dimer interface [polypeptide binding]; other site
568709008539	putative PBP binding regions; other site
568709008540	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
568709008541	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
568709008542	ABC-ATPase subunit  interface; other site
568709008543	dimer interface [polypeptide binding]; other site
568709008544	putative PBP binding regions; other site
568709008545	effector protein YopJ; Provisional; Region: PRK15371
568709008546	transcriptional activator SprB; Provisional; Region: PRK15320
568709008547	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
568709008548	transcriptional regulator SirC; Provisional; Region: PRK15044
568709008549	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709008550	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
568709008551	invasion protein OrgB; Provisional; Region: PRK15322
568709008552	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
568709008553	invasion protein OrgA; Provisional; Region: PRK15323
568709008554	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
568709008555	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
568709008556	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
568709008557	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
568709008558	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
568709008559	transcriptional regulator HilD; Provisional; Region: PRK15185
568709008560	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709008561	invasion protein regulator; Provisional; Region: PRK12370
568709008562	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709008563	DNA binding site [nucleotide binding]
568709008564	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
568709008565	binding surface
568709008566	TPR motif; other site
568709008567	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
568709008568	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
568709008569	N-acetyl-D-glucosamine binding site [chemical binding]; other site
568709008570	catalytic residue [active]
568709008571	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
568709008572	SicP binding; Region: SicP-binding; pfam09119
568709008573	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
568709008574	switch II binding region; other site
568709008575	Rac1 P-loop interaction site [polypeptide binding]; other site
568709008576	GTP binding residues [chemical binding]; other site
568709008577	switch I binding region; other site
568709008578	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
568709008579	active site
568709008580	chaperone protein SicP; Provisional; Region: PRK15329
568709008581	putative acyl carrier protein IacP; Validated; Region: PRK08172
568709008582	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
568709008583	cell invasion protein SipD; Provisional; Region: PRK15330
568709008584	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
568709008585	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
568709008586	chaperone protein SicA; Provisional; Region: PRK15331
568709008587	Tetratricopeptide repeat; Region: TPR_3; pfam07720
568709008588	Tetratricopeptide repeat; Region: TPR_3; pfam07720
568709008589	type III secretion system protein SpaS; Validated; Region: PRK08156
568709008590	type III secretion system protein SpaR; Provisional; Region: PRK15332
568709008591	type III secretion system protein SpaQ; Provisional; Region: PRK15333
568709008592	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
568709008593	type III secretion system protein SpaO; Validated; Region: PRK08158
568709008594	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
568709008595	antigen presentation protein SpaN; Provisional; Region: PRK15334
568709008596	Surface presentation of antigens protein; Region: SPAN; pfam02510
568709008597	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
568709008598	ATP synthase SpaL; Validated; Region: PRK08149
568709008599	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
568709008600	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
568709008601	Walker A motif; other site
568709008602	ATP binding site [chemical binding]; other site
568709008603	Walker B motif; other site
568709008604	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
568709008605	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
568709008606	type III secretion system protein InvA; Provisional; Region: PRK15337
568709008607	type III secretion system regulator InvE; Provisional; Region: PRK15338
568709008608	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
568709008609	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
568709008610	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
568709008611	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
568709008612	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
568709008613	transcriptional regulator InvF; Provisional; Region: PRK15340
568709008614	InvH outer membrane lipoprotein; Region: InvH; pfam04741
568709008615	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
568709008616	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
568709008618	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
568709008619	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
568709008620	active site
568709008621	metal binding site [ion binding]; metal-binding site
568709008622	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
568709008623	MutS domain I; Region: MutS_I; pfam01624
568709008624	MutS domain II; Region: MutS_II; pfam05188
568709008625	MutS domain III; Region: MutS_III; pfam05192
568709008626	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
568709008627	Walker A/P-loop; other site
568709008628	ATP binding site [chemical binding]; other site
568709008629	Q-loop/lid; other site
568709008630	ABC transporter signature motif; other site
568709008631	Walker B; other site
568709008632	D-loop; other site
568709008633	H-loop/switch region; other site
568709008634	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
568709008635	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709008636	Major Facilitator Superfamily; Region: MFS_1; pfam07690
568709008637	putative substrate translocation pore; other site
568709008638	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709008639	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709008640	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
568709008641	putative effector binding pocket; other site
568709008642	dimerization interface [polypeptide binding]; other site
568709008643	GntP family permease; Region: GntP_permease; pfam02447
568709008644	fructuronate transporter; Provisional; Region: PRK10034; cl15264
568709008645	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
568709008646	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
568709008647	putative NAD(P) binding site [chemical binding]; other site
568709008648	active site
568709008649	putative substrate binding site [chemical binding]; other site
568709008650	hypothetical protein; Provisional; Region: PRK09989
568709008651	putative aldolase; Validated; Region: PRK08130
568709008652	intersubunit interface [polypeptide binding]; other site
568709008653	active site
568709008654	Zn2+ binding site [ion binding]; other site
568709008655	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
568709008656	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
568709008657	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
568709008658	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568709008659	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
568709008660	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709008661	MarR family; Region: MarR_2; cl17246
568709008662	Transcriptional regulators [Transcription]; Region: MarR; COG1846
568709008663	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
568709008664	Flavoprotein; Region: Flavoprotein; pfam02441
568709008665	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
568709008667	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
568709008668	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568709008669	Peptidase family M23; Region: Peptidase_M23; pfam01551
568709008670	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
568709008671	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709008672	S-adenosylmethionine binding site [chemical binding]; other site
568709008673	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
568709008674	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
568709008675	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
568709008676	Permutation of conserved domain; other site
568709008677	active site
568709008678	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
568709008679	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
568709008680	homotrimer interaction site [polypeptide binding]; other site
568709008681	zinc binding site [ion binding]; other site
568709008682	CDP-binding sites; other site
568709008683	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
568709008684	substrate binding site; other site
568709008685	dimer interface; other site
568709008686	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
568709008687	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
568709008689	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
568709008690	ligand-binding site [chemical binding]; other site
568709008691	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
568709008692	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
568709008693	CysD dimerization site [polypeptide binding]; other site
568709008694	G1 box; other site
568709008695	putative GEF interaction site [polypeptide binding]; other site
568709008696	GTP/Mg2+ binding site [chemical binding]; other site
568709008697	Switch I region; other site
568709008698	G2 box; other site
568709008699	G3 box; other site
568709008700	Switch II region; other site
568709008701	G4 box; other site
568709008702	G5 box; other site
568709008703	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
568709008704	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
568709008705	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
568709008706	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
568709008707	Active Sites [active]
568709008708	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
568709008709	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
568709008710	metal binding site [ion binding]; metal-binding site
568709008711	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
568709008712	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
568709008713	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
568709008714	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
568709008715	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
568709008716	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
568709008717	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09731
568709008718	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
568709008719	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
568709008720	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
568709008721	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
568709008722	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
568709008723	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
568709008724	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
568709008725	Active Sites [active]
568709008726	sulfite reductase subunit beta; Provisional; Region: PRK13504
568709008727	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
568709008728	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
568709008729	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
568709008730	Flavodoxin; Region: Flavodoxin_1; pfam00258
568709008731	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
568709008732	FAD binding pocket [chemical binding]; other site
568709008733	FAD binding motif [chemical binding]; other site
568709008734	catalytic residues [active]
568709008735	NAD binding pocket [chemical binding]; other site
568709008736	phosphate binding motif [ion binding]; other site
568709008737	beta-alpha-beta structure motif; other site
568709008738	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
568709008739	active site
568709008740	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
568709008741	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
568709008742	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
568709008743	enolase; Provisional; Region: eno; PRK00077
568709008744	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
568709008745	dimer interface [polypeptide binding]; other site
568709008746	metal binding site [ion binding]; metal-binding site
568709008747	substrate binding pocket [chemical binding]; other site
568709008748	CTP synthetase; Validated; Region: pyrG; PRK05380
568709008749	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
568709008750	Catalytic site [active]
568709008751	active site
568709008752	UTP binding site [chemical binding]; other site
568709008753	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
568709008754	active site
568709008755	putative oxyanion hole; other site
568709008756	catalytic triad [active]
568709008757	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
568709008758	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
568709008759	homodimer interface [polypeptide binding]; other site
568709008760	metal binding site [ion binding]; metal-binding site
568709008761	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
568709008762	homodimer interface [polypeptide binding]; other site
568709008763	active site
568709008764	putative chemical substrate binding site [chemical binding]; other site
568709008765	metal binding site [ion binding]; metal-binding site
568709008766	Fimbrial protein; Region: Fimbrial; cl01416
568709008767	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
568709008768	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
568709008769	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
568709008770	HD domain; Region: HD_4; pfam13328
568709008771	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
568709008772	synthetase active site [active]
568709008773	NTP binding site [chemical binding]; other site
568709008774	metal binding site [ion binding]; metal-binding site
568709008775	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
568709008776	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
568709008777	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
568709008778	TRAM domain; Region: TRAM; pfam01938
568709008779	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709008780	S-adenosylmethionine binding site [chemical binding]; other site
568709008781	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
568709008782	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
568709008783	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709008784	dimerization interface [polypeptide binding]; other site
568709008785	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709008786	dimer interface [polypeptide binding]; other site
568709008787	phosphorylation site [posttranslational modification]
568709008788	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709008789	ATP binding site [chemical binding]; other site
568709008790	Mg2+ binding site [ion binding]; other site
568709008791	G-X-G motif; other site
568709008792	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
568709008793	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709008794	active site
568709008795	phosphorylation site [posttranslational modification]
568709008796	intermolecular recognition site; other site
568709008797	dimerization interface [polypeptide binding]; other site
568709008798	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
568709008799	putative binding surface; other site
568709008800	active site
568709008801	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
568709008802	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
568709008803	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
568709008804	active site
568709008805	tetramer interface [polypeptide binding]; other site
568709008806	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
568709008807	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
568709008808	active site
568709008809	tetramer interface [polypeptide binding]; other site
568709008810	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709008811	D-galactonate transporter; Region: 2A0114; TIGR00893
568709008812	putative substrate translocation pore; other site
568709008813	flavodoxin; Provisional; Region: PRK08105
568709008814	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
568709008815	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
568709008816	probable active site [active]
568709008817	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
568709008818	SecY interacting protein Syd; Provisional; Region: PRK04968
568709008819	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
568709008820	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
568709008821	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
568709008822	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
568709008823	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
568709008825	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
568709008826	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
568709008827	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
568709008828	flap endonuclease-like protein; Provisional; Region: PRK09482
568709008829	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
568709008830	active site
568709008831	metal binding site 1 [ion binding]; metal-binding site
568709008832	putative 5' ssDNA interaction site; other site
568709008833	metal binding site 3; metal-binding site
568709008834	metal binding site 2 [ion binding]; metal-binding site
568709008835	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
568709008836	putative DNA binding site [nucleotide binding]; other site
568709008837	putative metal binding site [ion binding]; other site
568709008838	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
568709008839	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
568709008840	dimer interface [polypeptide binding]; other site
568709008841	active site
568709008842	metal binding site [ion binding]; metal-binding site
568709008843	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
568709008844	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
568709008845	intersubunit interface [polypeptide binding]; other site
568709008846	active site
568709008847	Zn2+ binding site [ion binding]; other site
568709008848	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
568709008849	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709008850	putative substrate translocation pore; other site
568709008851	L-fucose isomerase; Provisional; Region: fucI; PRK10991
568709008852	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
568709008853	hexamer (dimer of trimers) interface [polypeptide binding]; other site
568709008854	trimer interface [polypeptide binding]; other site
568709008855	substrate binding site [chemical binding]; other site
568709008856	Mn binding site [ion binding]; other site
568709008857	L-fuculokinase; Provisional; Region: PRK10331
568709008858	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
568709008859	nucleotide binding site [chemical binding]; other site
568709008860	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
568709008861	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
568709008862	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
568709008863	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709008864	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
568709008865	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
568709008866	hypothetical protein; Provisional; Region: PRK10873
568709008867	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
568709008868	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709008869	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
568709008870	dimerization interface [polypeptide binding]; other site
568709008871	substrate binding pocket [chemical binding]; other site
568709008872	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
568709008873	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
568709008874	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
568709008875	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568709008876	catalytic residue [active]
568709008877	CsdA-binding activator; Provisional; Region: PRK15019
568709008878	Predicted permeases [General function prediction only]; Region: RarD; COG2962
568709008879	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
568709008880	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
568709008881	putative ATP binding site [chemical binding]; other site
568709008882	putative substrate interface [chemical binding]; other site
568709008883	murein transglycosylase A; Provisional; Region: mltA; PRK11162
568709008884	murein hydrolase B; Provisional; Region: PRK10760; cl17906
568709008885	MltA specific insert domain; Region: MltA; pfam03562
568709008886	3D domain; Region: 3D; pfam06725
568709008887	AMIN domain; Region: AMIN; pfam11741
568709008888	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
568709008889	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
568709008890	active site
568709008891	metal binding site [ion binding]; metal-binding site
568709008892	N-acetylglutamate synthase; Validated; Region: PRK05279
568709008893	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
568709008894	putative feedback inhibition sensing region; other site
568709008895	putative nucleotide binding site [chemical binding]; other site
568709008896	putative substrate binding site [chemical binding]; other site
568709008897	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709008898	Coenzyme A binding pocket [chemical binding]; other site
568709008899	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
568709008900	AAA domain; Region: AAA_30; pfam13604
568709008901	Family description; Region: UvrD_C_2; pfam13538
568709008902	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
568709008903	protease3; Provisional; Region: PRK15101
568709008904	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
568709008905	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
568709008906	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
568709008907	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
568709008908	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
568709008909	hypothetical protein; Provisional; Region: PRK10332
568709008910	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
568709008911	hypothetical protein; Provisional; Region: PRK11521
568709008912	hypothetical protein; Provisional; Region: PRK10557
568709008913	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
568709008914	hypothetical protein; Provisional; Region: PRK10506
568709008915	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
568709008916	thymidylate synthase; Reviewed; Region: thyA; PRK01827
568709008917	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
568709008918	dimerization interface [polypeptide binding]; other site
568709008919	active site
568709008920	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
568709008921	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
568709008922	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
568709008923	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
568709008924	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
568709008925	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
568709008926	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
568709008927	putative active site [active]
568709008928	Ap4A binding site [chemical binding]; other site
568709008929	nudix motif; other site
568709008930	putative metal binding site [ion binding]; other site
568709008931	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
568709008932	putative DNA-binding cleft [nucleotide binding]; other site
568709008933	putative DNA clevage site; other site
568709008934	molecular lever; other site
568709008935	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
568709008936	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
568709008937	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568709008938	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568709008939	active site
568709008940	catalytic tetrad [active]
568709008941	lysophospholipid transporter LplT; Provisional; Region: PRK11195
568709008942	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709008943	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
568709008944	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
568709008945	putative acyl-acceptor binding pocket; other site
568709008946	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
568709008947	acyl-activating enzyme (AAE) consensus motif; other site
568709008948	putative AMP binding site [chemical binding]; other site
568709008949	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
568709008950	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709008951	DNA binding site [nucleotide binding]
568709008952	domain linker motif; other site
568709008953	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
568709008954	dimerization interface (closed form) [polypeptide binding]; other site
568709008955	ligand binding site [chemical binding]; other site
568709008956	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568709008957	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709008958	DNA binding site [nucleotide binding]
568709008959	domain linker motif; other site
568709008960	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
568709008961	dimerization interface (closed form) [polypeptide binding]; other site
568709008962	ligand binding site [chemical binding]; other site
568709008963	diaminopimelate decarboxylase; Provisional; Region: PRK11165
568709008964	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
568709008965	active site
568709008966	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
568709008967	substrate binding site [chemical binding]; other site
568709008968	catalytic residues [active]
568709008969	dimer interface [polypeptide binding]; other site
568709008970	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
568709008971	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709008972	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709008973	dimerization interface [polypeptide binding]; other site
568709008974	putative racemase; Provisional; Region: PRK10200
568709008975	aspartate racemase; Region: asp_race; TIGR00035
568709008976	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
568709008977	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709008978	putative substrate translocation pore; other site
568709008979	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709008980	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
568709008981	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
568709008982	NADP binding site [chemical binding]; other site
568709008983	homodimer interface [polypeptide binding]; other site
568709008984	active site
568709008985	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
568709008986	putative acyltransferase; Provisional; Region: PRK05790
568709008987	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
568709008988	dimer interface [polypeptide binding]; other site
568709008989	active site
568709008990	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709008991	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709008992	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568709008993	dimerization interface [polypeptide binding]; other site
568709008994	Predicted membrane protein [Function unknown]; Region: COG4125
568709008995	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
568709008996	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
568709008997	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
568709008998	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
568709008999	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
568709009000	putative metal binding site [ion binding]; other site
568709009001	putative homodimer interface [polypeptide binding]; other site
568709009002	putative homotetramer interface [polypeptide binding]; other site
568709009003	putative homodimer-homodimer interface [polypeptide binding]; other site
568709009004	putative allosteric switch controlling residues; other site
568709009005	transcriptional activator SprB; Provisional; Region: PRK15320
568709009006	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14600
568709009007	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
568709009008	Fimbrial protein; Region: Fimbrial; pfam00419
568709009009	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
568709009010	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709009011	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709009012	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
568709009013	PapC N-terminal domain; Region: PapC_N; pfam13954
568709009014	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709009015	PapC C-terminal domain; Region: PapC_C; pfam13953
568709009016	fimbrial protein StdA; Provisional; Region: PRK15210
568709009017	hypothetical protein; Provisional; Region: PRK10316
568709009018	YfdX protein; Region: YfdX; pfam10938
568709009019	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
568709009020	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
568709009021	oligomeric interface; other site
568709009022	putative active site [active]
568709009023	homodimer interface [polypeptide binding]; other site
568709009024	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
568709009025	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
568709009026	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
568709009027	Peptidase family M23; Region: Peptidase_M23; pfam01551
568709009028	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
568709009029	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
568709009030	active site
568709009031	metal binding site [ion binding]; metal-binding site
568709009032	nudix motif; other site
568709009033	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
568709009034	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
568709009035	dimer interface [polypeptide binding]; other site
568709009036	putative anticodon binding site; other site
568709009037	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
568709009038	motif 1; other site
568709009039	active site
568709009040	motif 2; other site
568709009041	motif 3; other site
568709009042	This domain is found in peptide chain release factors; Region: PCRF; smart00937
568709009043	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
568709009044	RF-1 domain; Region: RF-1; pfam00472
568709009045	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
568709009046	DHH family; Region: DHH; pfam01368
568709009047	DHHA1 domain; Region: DHHA1; pfam02272
568709009048	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
568709009049	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
568709009050	dimerization domain [polypeptide binding]; other site
568709009051	dimer interface [polypeptide binding]; other site
568709009052	catalytic residues [active]
568709009053	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
568709009054	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
568709009055	active site
568709009056	Int/Topo IB signature motif; other site
568709009057	flavodoxin FldB; Provisional; Region: PRK12359
568709009058	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
568709009059	hypothetical protein; Provisional; Region: PRK10878
568709009060	putative global regulator; Reviewed; Region: PRK09559
568709009061	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
568709009062	hemolysin; Provisional; Region: PRK15087
568709009063	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
568709009064	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
568709009065	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
568709009066	beta-galactosidase; Region: BGL; TIGR03356
568709009067	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
568709009068	glycine dehydrogenase; Provisional; Region: PRK05367
568709009069	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
568709009070	tetramer interface [polypeptide binding]; other site
568709009071	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709009072	catalytic residue [active]
568709009073	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
568709009074	tetramer interface [polypeptide binding]; other site
568709009075	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709009076	catalytic residue [active]
568709009077	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
568709009078	lipoyl attachment site [posttranslational modification]; other site
568709009079	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
568709009080	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
568709009081	oxidoreductase; Provisional; Region: PRK08013
568709009082	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
568709009083	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
568709009084	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
568709009085	proline aminopeptidase P II; Provisional; Region: PRK10879
568709009086	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
568709009087	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
568709009088	active site
568709009089	hypothetical protein; Reviewed; Region: PRK01736
568709009090	Z-ring-associated protein; Provisional; Region: PRK10972
568709009091	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
568709009092	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
568709009093	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
568709009094	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
568709009095	ligand binding site [chemical binding]; other site
568709009096	NAD binding site [chemical binding]; other site
568709009097	tetramer interface [polypeptide binding]; other site
568709009098	catalytic site [active]
568709009099	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
568709009100	L-serine binding site [chemical binding]; other site
568709009101	ACT domain interface; other site
568709009102	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
568709009103	tetramer (dimer of dimers) interface [polypeptide binding]; other site
568709009104	active site
568709009105	dimer interface [polypeptide binding]; other site
568709009106	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
568709009107	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709009108	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
568709009109	putative dimerization interface [polypeptide binding]; other site
568709009110	Uncharacterized conserved protein [Function unknown]; Region: COG2968
568709009111	oxidative stress defense protein; Provisional; Region: PRK11087
568709009112	arginine exporter protein; Provisional; Region: PRK09304
568709009113	mechanosensitive channel MscS; Provisional; Region: PRK10334
568709009114	Mechanosensitive ion channel; Region: MS_channel; pfam00924
568709009115	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
568709009116	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
568709009117	active site
568709009118	intersubunit interface [polypeptide binding]; other site
568709009119	zinc binding site [ion binding]; other site
568709009120	Na+ binding site [ion binding]; other site
568709009121	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
568709009122	Phosphoglycerate kinase; Region: PGK; pfam00162
568709009123	substrate binding site [chemical binding]; other site
568709009124	hinge regions; other site
568709009125	ADP binding site [chemical binding]; other site
568709009126	catalytic site [active]
568709009127	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
568709009128	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
568709009129	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
568709009130	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
568709009131	trimer interface [polypeptide binding]; other site
568709009132	putative Zn binding site [ion binding]; other site
568709009133	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
568709009134	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
568709009135	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
568709009136	Walker A/P-loop; other site
568709009137	ATP binding site [chemical binding]; other site
568709009138	Q-loop/lid; other site
568709009139	ABC transporter signature motif; other site
568709009140	Walker B; other site
568709009141	D-loop; other site
568709009142	H-loop/switch region; other site
568709009143	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
568709009144	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
568709009145	Walker A/P-loop; other site
568709009146	ATP binding site [chemical binding]; other site
568709009147	Q-loop/lid; other site
568709009148	ABC transporter signature motif; other site
568709009149	Walker B; other site
568709009150	D-loop; other site
568709009151	H-loop/switch region; other site
568709009152	transketolase; Reviewed; Region: PRK12753
568709009153	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
568709009154	TPP-binding site [chemical binding]; other site
568709009155	dimer interface [polypeptide binding]; other site
568709009156	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
568709009157	PYR/PP interface [polypeptide binding]; other site
568709009158	dimer interface [polypeptide binding]; other site
568709009159	TPP binding site [chemical binding]; other site
568709009160	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
568709009161	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
568709009162	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
568709009163	agmatinase; Region: agmatinase; TIGR01230
568709009164	oligomer interface [polypeptide binding]; other site
568709009165	putative active site [active]
568709009166	Mn binding site [ion binding]; other site
568709009167	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
568709009168	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
568709009169	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
568709009170	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
568709009171	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
568709009172	putative NAD(P) binding site [chemical binding]; other site
568709009173	catalytic Zn binding site [ion binding]; other site
568709009174	structural Zn binding site [ion binding]; other site
568709009175	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
568709009176	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
568709009177	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
568709009178	Transcriptional regulators [Transcription]; Region: FadR; COG2186
568709009179	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709009180	DNA-binding site [nucleotide binding]; DNA binding site
568709009181	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
568709009182	DNA phosphorothioation-dependent restriction protein DptH; Region: dnd_assoc_2; TIGR03237
568709009183	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
568709009184	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
568709009185	dimer interface [polypeptide binding]; other site
568709009186	active site
568709009187	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
568709009188	catalytic residues [active]
568709009189	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
568709009190	Virulence promoting factor; Region: YqgB; pfam11036
568709009191	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
568709009192	S-adenosylmethionine synthetase; Validated; Region: PRK05250
568709009193	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
568709009194	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
568709009195	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
568709009196	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
568709009197	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709009198	putative substrate translocation pore; other site
568709009199	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709009200	hypothetical protein; Provisional; Region: PRK04860
568709009201	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
568709009202	DNA-specific endonuclease I; Provisional; Region: PRK15137
568709009203	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
568709009204	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
568709009205	RNA methyltransferase, RsmE family; Region: TIGR00046
568709009206	glutathione synthetase; Provisional; Region: PRK05246
568709009207	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
568709009208	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
568709009209	hypothetical protein; Validated; Region: PRK00228
568709009210	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
568709009211	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
568709009212	Transcriptional regulator [Transcription]; Region: IclR; COG1414
568709009213	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
568709009214	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
568709009215	Walker A motif; other site
568709009216	ATP binding site [chemical binding]; other site
568709009217	Walker B motif; other site
568709009218	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
568709009219	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
568709009220	catalytic residue [active]
568709009221	YGGT family; Region: YGGT; pfam02325
568709009222	YGGT family; Region: YGGT; pfam02325
568709009223	hypothetical protein; Validated; Region: PRK05090
568709009224	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
568709009225	active site
568709009226	dimerization interface [polypeptide binding]; other site
568709009227	HemN family oxidoreductase; Provisional; Region: PRK05660
568709009228	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709009229	FeS/SAM binding site; other site
568709009230	HemN C-terminal domain; Region: HemN_C; pfam06969
568709009231	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
568709009232	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
568709009233	homodimer interface [polypeptide binding]; other site
568709009234	active site
568709009235	hypothetical protein; Provisional; Region: PRK10626
568709009236	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
568709009237	hypothetical protein; Provisional; Region: PRK11702
568709009238	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
568709009239	adenine DNA glycosylase; Provisional; Region: PRK10880
568709009240	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
568709009241	minor groove reading motif; other site
568709009242	helix-hairpin-helix signature motif; other site
568709009243	substrate binding pocket [chemical binding]; other site
568709009244	active site
568709009245	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
568709009246	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
568709009247	DNA binding and oxoG recognition site [nucleotide binding]
568709009248	oxidative damage protection protein; Provisional; Region: PRK05408
568709009249	murein transglycosylase C; Provisional; Region: mltC; PRK11671
568709009250	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
568709009251	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
568709009252	N-acetyl-D-glucosamine binding site [chemical binding]; other site
568709009253	catalytic residue [active]
568709009254	nucleoside transporter; Region: 2A0110; TIGR00889
568709009255	ornithine decarboxylase; Provisional; Region: PRK13578
568709009256	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
568709009257	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
568709009258	homodimer interface [polypeptide binding]; other site
568709009259	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709009260	catalytic residue [active]
568709009261	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
568709009262	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
568709009263	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
568709009264	dimer interface [polypeptide binding]; other site
568709009265	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
568709009266	metal binding site [ion binding]; metal-binding site
568709009267	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
568709009268	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
568709009269	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
568709009270	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
568709009271	putative active site [active]
568709009272	putative catalytic site [active]
568709009273	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
568709009274	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
568709009275	putative dimerization interface [polypeptide binding]; other site
568709009276	putative substrate binding pocket [chemical binding]; other site
568709009277	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
568709009278	Sulfatase; Region: Sulfatase; pfam00884
568709009279	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
568709009280	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709009281	FeS/SAM binding site; other site
568709009282	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
568709009283	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
568709009284	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709009285	DNA binding residues [nucleotide binding]
568709009286	dimerization interface [polypeptide binding]; other site
568709009287	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
568709009288	Amino acid permease; Region: AA_permease_2; pfam13520
568709009289	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
568709009290	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
568709009291	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
568709009292	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
568709009293	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
568709009294	NAD(P) binding site [chemical binding]; other site
568709009295	catalytic residues [active]
568709009296	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
568709009297	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
568709009298	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
568709009299	active site
568709009300	catalytic site [active]
568709009301	Zn binding site [ion binding]; other site
568709009302	tetramer interface [polypeptide binding]; other site
568709009303	Predicted amidohydrolase [General function prediction only]; Region: COG0388
568709009304	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
568709009305	putative active site [active]
568709009306	catalytic triad [active]
568709009307	putative dimer interface [polypeptide binding]; other site
568709009308	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709009309	D-galactonate transporter; Region: 2A0114; TIGR00893
568709009310	putative substrate translocation pore; other site
568709009311	mannonate dehydratase; Provisional; Region: PRK03906
568709009312	mannonate dehydratase; Region: uxuA; TIGR00695
568709009313	D-mannonate oxidoreductase; Provisional; Region: PRK15037
568709009314	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
568709009315	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
568709009316	Glucuronate isomerase; Region: UxaC; pfam02614
568709009317	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
568709009318	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
568709009319	dimer interface [polypeptide binding]; other site
568709009320	putative CheW interface [polypeptide binding]; other site
568709009321	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
568709009322	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
568709009323	CHAP domain; Region: CHAP; pfam05257
568709009324	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
568709009325	putative S-transferase; Provisional; Region: PRK11752
568709009326	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
568709009327	C-terminal domain interface [polypeptide binding]; other site
568709009328	GSH binding site (G-site) [chemical binding]; other site
568709009329	dimer interface [polypeptide binding]; other site
568709009330	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
568709009331	dimer interface [polypeptide binding]; other site
568709009332	N-terminal domain interface [polypeptide binding]; other site
568709009333	active site
568709009334	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
568709009335	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
568709009336	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
568709009337	putative ligand binding residues [chemical binding]; other site
568709009338	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
568709009339	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
568709009340	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
568709009341	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
568709009342	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
568709009343	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
568709009344	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
568709009345	putative substrate-binding site; other site
568709009346	nickel binding site [ion binding]; other site
568709009347	hydrogenase 2 large subunit; Provisional; Region: PRK10467
568709009348	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
568709009349	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
568709009350	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
568709009351	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
568709009352	4Fe-4S binding domain; Region: Fer4_6; pfam12837
568709009353	hydrogenase 2 small subunit; Provisional; Region: PRK10468
568709009354	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
568709009355	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
568709009356	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
568709009357	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
568709009358	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709009359	dimerization interface [polypeptide binding]; other site
568709009360	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
568709009361	dimer interface [polypeptide binding]; other site
568709009362	putative CheW interface [polypeptide binding]; other site
568709009363	hypothetical protein; Provisional; Region: PRK05208
568709009364	oxidoreductase; Provisional; Region: PRK07985
568709009365	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
568709009366	NAD binding site [chemical binding]; other site
568709009367	metal binding site [ion binding]; metal-binding site
568709009368	active site
568709009369	biopolymer transport protein ExbD; Provisional; Region: PRK11267
568709009370	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
568709009371	biopolymer transport protein ExbB; Provisional; Region: PRK10414
568709009372	cystathionine beta-lyase; Provisional; Region: PRK08114
568709009373	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
568709009374	homodimer interface [polypeptide binding]; other site
568709009375	substrate-cofactor binding pocket; other site
568709009376	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709009377	catalytic residue [active]
568709009378	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
568709009379	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
568709009380	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
568709009381	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
568709009382	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709009383	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709009384	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
568709009385	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
568709009386	dimer interface [polypeptide binding]; other site
568709009387	active site
568709009388	metal binding site [ion binding]; metal-binding site
568709009389	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
568709009390	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
568709009391	active site
568709009392	catalytic tetrad [active]
568709009393	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
568709009394	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
568709009395	transmembrane helices; other site
568709009396	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
568709009397	nucleotide binding site/active site [active]
568709009398	catalytic residue [active]
568709009399	hypothetical protein; Provisional; Region: PRK01254
568709009400	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
568709009401	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
568709009402	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
568709009403	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
568709009404	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
568709009405	DctM-like transporters; Region: DctM; pfam06808
568709009406	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
568709009407	FtsI repressor; Provisional; Region: PRK10883
568709009408	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
568709009409	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
568709009410	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
568709009411	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
568709009412	putative acyl-acceptor binding pocket; other site
568709009413	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
568709009414	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
568709009415	CAP-like domain; other site
568709009416	active site
568709009417	primary dimer interface [polypeptide binding]; other site
568709009418	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
568709009419	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568709009420	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709009421	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
568709009422	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
568709009423	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
568709009424	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709009425	active site
568709009426	phosphorylation site [posttranslational modification]
568709009427	intermolecular recognition site; other site
568709009428	dimerization interface [polypeptide binding]; other site
568709009429	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709009430	DNA binding site [nucleotide binding]
568709009431	sensor protein QseC; Provisional; Region: PRK10337
568709009432	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
568709009433	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709009434	dimer interface [polypeptide binding]; other site
568709009435	phosphorylation site [posttranslational modification]
568709009436	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709009437	ATP binding site [chemical binding]; other site
568709009438	Mg2+ binding site [ion binding]; other site
568709009439	G-X-G motif; other site
568709009440	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
568709009441	Uncharacterized conserved protein [Function unknown]; Region: COG1359
568709009442	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
568709009443	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709009444	ATP binding site [chemical binding]; other site
568709009445	Mg2+ binding site [ion binding]; other site
568709009446	G-X-G motif; other site
568709009447	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
568709009448	anchoring element; other site
568709009449	dimer interface [polypeptide binding]; other site
568709009450	ATP binding site [chemical binding]; other site
568709009451	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
568709009452	active site
568709009453	metal binding site [ion binding]; metal-binding site
568709009454	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
568709009455	esterase YqiA; Provisional; Region: PRK11071
568709009456	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
568709009457	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
568709009458	active site
568709009459	metal binding site [ion binding]; metal-binding site
568709009460	hexamer interface [polypeptide binding]; other site
568709009461	putative dehydrogenase; Provisional; Region: PRK11039
568709009462	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
568709009463	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
568709009464	dimer interface [polypeptide binding]; other site
568709009465	ADP-ribose binding site [chemical binding]; other site
568709009466	active site
568709009467	nudix motif; other site
568709009468	metal binding site [ion binding]; metal-binding site
568709009469	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
568709009470	hypothetical protein; Provisional; Region: PRK11653
568709009471	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
568709009472	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
568709009473	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
568709009474	putative active site [active]
568709009475	metal binding site [ion binding]; metal-binding site
568709009476	zinc transporter ZupT; Provisional; Region: PRK04201
568709009477	ZIP Zinc transporter; Region: Zip; pfam02535
568709009478	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
568709009479	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
568709009480	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
568709009481	catalytic residues [active]
568709009482	hinge region; other site
568709009483	alpha helical domain; other site
568709009484	putative disulfide oxidoreductase; Provisional; Region: PRK04307
568709009485	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
568709009486	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
568709009487	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
568709009488	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
568709009489	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
568709009490	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
568709009491	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
568709009492	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
568709009493	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
568709009494	putative ribose interaction site [chemical binding]; other site
568709009495	putative ADP binding site [chemical binding]; other site
568709009496	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
568709009497	active site
568709009498	nucleotide binding site [chemical binding]; other site
568709009499	HIGH motif; other site
568709009500	KMSKS motif; other site
568709009501	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
568709009502	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
568709009503	metal binding triad; other site
568709009504	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
568709009505	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
568709009506	metal binding triad; other site
568709009507	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
568709009508	Uncharacterized conserved protein [Function unknown]; Region: COG3025
568709009509	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
568709009510	putative active site [active]
568709009511	putative metal binding residues [ion binding]; other site
568709009512	signature motif; other site
568709009513	putative triphosphate binding site [ion binding]; other site
568709009514	CHAD domain; Region: CHAD; pfam05235
568709009515	SH3 domain-containing protein; Provisional; Region: PRK10884
568709009516	Bacterial SH3 domain homologues; Region: SH3b; smart00287
568709009517	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
568709009518	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
568709009519	active site
568709009520	NTP binding site [chemical binding]; other site
568709009521	metal binding triad [ion binding]; metal-binding site
568709009522	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
568709009523	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568709009524	Zn2+ binding site [ion binding]; other site
568709009525	Mg2+ binding site [ion binding]; other site
568709009526	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
568709009527	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
568709009528	homooctamer interface [polypeptide binding]; other site
568709009529	active site
568709009530	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
568709009531	Fumarate hydratase (Fumerase); Region: Fumerase; cl00851
568709009532	UGMP family protein; Validated; Region: PRK09604
568709009533	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
568709009534	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
568709009535	DNA primase; Validated; Region: dnaG; PRK05667
568709009536	CHC2 zinc finger; Region: zf-CHC2; pfam01807
568709009537	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
568709009538	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
568709009539	active site
568709009540	metal binding site [ion binding]; metal-binding site
568709009541	interdomain interaction site; other site
568709009542	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
568709009543	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
568709009544	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
568709009545	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
568709009546	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
568709009547	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
568709009548	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
568709009549	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
568709009550	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
568709009551	DNA binding residues [nucleotide binding]
568709009552	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
568709009553	active site
568709009554	SUMO-1 interface [polypeptide binding]; other site
568709009555	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
568709009556	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
568709009557	FAD binding pocket [chemical binding]; other site
568709009558	FAD binding motif [chemical binding]; other site
568709009559	phosphate binding motif [ion binding]; other site
568709009560	NAD binding pocket [chemical binding]; other site
568709009561	Predicted transcriptional regulators [Transcription]; Region: COG1695
568709009562	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
568709009563	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
568709009564	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709009565	dimerization interface [polypeptide binding]; other site
568709009566	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
568709009567	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
568709009568	dimer interface [polypeptide binding]; other site
568709009569	putative CheW interface [polypeptide binding]; other site
568709009570	PAS fold; Region: PAS_3; pfam08447
568709009571	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
568709009572	putative active site [active]
568709009573	heme pocket [chemical binding]; other site
568709009574	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
568709009575	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
568709009576	dimer interface [polypeptide binding]; other site
568709009577	putative CheW interface [polypeptide binding]; other site
568709009578	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
568709009579	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
568709009580	inhibitor-cofactor binding pocket; inhibition site
568709009581	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709009582	catalytic residue [active]
568709009583	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
568709009584	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
568709009585	active site
568709009586	FMN binding site [chemical binding]; other site
568709009587	2,4-decadienoyl-CoA binding site; other site
568709009588	catalytic residue [active]
568709009589	4Fe-4S cluster binding site [ion binding]; other site
568709009590	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
568709009591	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568709009592	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
568709009593	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709009594	S-adenosylmethionine binding site [chemical binding]; other site
568709009595	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
568709009596	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
568709009597	putative active site [active]
568709009598	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568709009599	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568709009600	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
568709009602	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
568709009603	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
568709009604	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
568709009605	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
568709009606	Predicted membrane protein [Function unknown]; Region: COG5393
568709009607	YqjK-like protein; Region: YqjK; pfam13997
568709009608	Predicted membrane protein [Function unknown]; Region: COG2259
568709009609	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
568709009610	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
568709009611	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
568709009612	putative dimer interface [polypeptide binding]; other site
568709009613	N-terminal domain interface [polypeptide binding]; other site
568709009614	putative substrate binding pocket (H-site) [chemical binding]; other site
568709009615	Predicted membrane protein [Function unknown]; Region: COG3152
568709009616	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709009617	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
568709009618	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709009619	dimerization interface [polypeptide binding]; other site
568709009620	Pirin-related protein [General function prediction only]; Region: COG1741
568709009621	Pirin; Region: Pirin; pfam02678
568709009622	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
568709009623	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
568709009624	serine transporter; Region: stp; TIGR00814
568709009625	L-serine dehydratase TdcG; Provisional; Region: PRK15040
568709009626	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
568709009627	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
568709009628	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
568709009629	Pyruvate formate lyase 1; Region: PFL1; cd01678
568709009630	coenzyme A binding site [chemical binding]; other site
568709009631	active site
568709009632	catalytic residues [active]
568709009633	glycine loop; other site
568709009634	propionate/acetate kinase; Provisional; Region: PRK12379
568709009635	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
568709009636	threonine/serine transporter TdcC; Provisional; Region: PRK13629
568709009637	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
568709009638	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
568709009639	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
568709009640	tetramer interface [polypeptide binding]; other site
568709009641	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709009642	catalytic residue [active]
568709009643	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
568709009644	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709009645	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
568709009646	putative substrate binding pocket [chemical binding]; other site
568709009647	putative dimerization interface [polypeptide binding]; other site
568709009648	glycerate kinase I; Provisional; Region: PRK10342
568709009649	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
568709009650	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
568709009651	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
568709009652	galactarate dehydratase; Region: galactar-dH20; TIGR03248
568709009653	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
568709009654	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
568709009655	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709009656	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
568709009657	substrate binding site [chemical binding]; other site
568709009658	ATP binding site [chemical binding]; other site
568709009659	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568709009660	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
568709009661	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709009662	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
568709009663	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
568709009664	intersubunit interface [polypeptide binding]; other site
568709009665	active site
568709009666	zinc binding site [ion binding]; other site
568709009667	Na+ binding site [ion binding]; other site
568709009668	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
568709009669	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
568709009670	putative substrate binding site [chemical binding]; other site
568709009671	putative ATP binding site [chemical binding]; other site
568709009672	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
568709009673	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568709009674	active site
568709009675	P-loop; other site
568709009676	phosphorylation site [posttranslational modification]
568709009677	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
568709009678	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709009679	active site
568709009680	phosphorylation site [posttranslational modification]
568709009681	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
568709009682	dimerization domain swap beta strand [polypeptide binding]; other site
568709009683	regulatory protein interface [polypeptide binding]; other site
568709009684	active site
568709009685	regulatory phosphorylation site [posttranslational modification]; other site
568709009686	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
568709009687	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709009688	active site
568709009689	phosphorylation site [posttranslational modification]
568709009690	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
568709009691	active site
568709009692	P-loop; other site
568709009693	phosphorylation site [posttranslational modification]
568709009694	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
568709009695	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
568709009696	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
568709009697	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
568709009698	putative NAD(P) binding site [chemical binding]; other site
568709009699	catalytic Zn binding site [ion binding]; other site
568709009700	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568709009701	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
568709009702	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709009703	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
568709009704	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
568709009705	putative SAM binding site [chemical binding]; other site
568709009706	putative homodimer interface [polypeptide binding]; other site
568709009707	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
568709009708	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
568709009709	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
568709009710	putative ligand binding site [chemical binding]; other site
568709009711	TIGR00252 family protein; Region: TIGR00252
568709009712	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
568709009713	dimer interface [polypeptide binding]; other site
568709009714	active site
568709009715	outer membrane lipoprotein; Provisional; Region: PRK11023
568709009716	BON domain; Region: BON; pfam04972
568709009717	BON domain; Region: BON; pfam04972
568709009718	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
568709009719	NADH(P)-binding; Region: NAD_binding_10; pfam13460
568709009720	NAD binding site [chemical binding]; other site
568709009721	active site
568709009722	intracellular protease, PfpI family; Region: PfpI; TIGR01382
568709009723	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
568709009724	proposed catalytic triad [active]
568709009725	conserved cys residue [active]
568709009726	hypothetical protein; Provisional; Region: PRK03467
568709009727	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
568709009728	GIY-YIG motif/motif A; other site
568709009729	putative active site [active]
568709009730	putative metal binding site [ion binding]; other site
568709009731	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
568709009732	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709009733	Coenzyme A binding pocket [chemical binding]; other site
568709009734	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
568709009735	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
568709009736	Peptidase family U32; Region: Peptidase_U32; pfam01136
568709009737	putative protease; Provisional; Region: PRK15447
568709009738	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
568709009739	hypothetical protein; Provisional; Region: PRK10508
568709009740	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
568709009741	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
568709009742	tryptophan permease; Provisional; Region: PRK10483
568709009743	aromatic amino acid transport protein; Region: araaP; TIGR00837
568709009744	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
568709009745	DEAD-like helicases superfamily; Region: DEXDc; smart00487
568709009746	ATP binding site [chemical binding]; other site
568709009747	Mg++ binding site [ion binding]; other site
568709009748	motif III; other site
568709009749	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709009750	nucleotide binding region [chemical binding]; other site
568709009751	ATP-binding site [chemical binding]; other site
568709009752	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
568709009753	putative RNA binding site [nucleotide binding]; other site
568709009754	lipoprotein NlpI; Provisional; Region: PRK11189
568709009755	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
568709009756	binding surface
568709009757	TPR motif; other site
568709009758	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
568709009759	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
568709009760	RNase E interface [polypeptide binding]; other site
568709009761	trimer interface [polypeptide binding]; other site
568709009762	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
568709009763	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
568709009764	RNase E interface [polypeptide binding]; other site
568709009765	trimer interface [polypeptide binding]; other site
568709009766	active site
568709009767	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
568709009768	putative nucleic acid binding region [nucleotide binding]; other site
568709009769	G-X-X-G motif; other site
568709009770	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
568709009771	RNA binding site [nucleotide binding]; other site
568709009772	domain interface; other site
568709009773	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
568709009774	16S/18S rRNA binding site [nucleotide binding]; other site
568709009775	S13e-L30e interaction site [polypeptide binding]; other site
568709009776	25S rRNA binding site [nucleotide binding]; other site
568709009777	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
568709009778	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
568709009779	RNA binding site [nucleotide binding]; other site
568709009780	active site
568709009781	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
568709009782	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
568709009783	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
568709009784	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
568709009785	translation initiation factor IF-2; Region: IF-2; TIGR00487
568709009786	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
568709009787	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
568709009788	G1 box; other site
568709009789	putative GEF interaction site [polypeptide binding]; other site
568709009790	GTP/Mg2+ binding site [chemical binding]; other site
568709009791	Switch I region; other site
568709009792	G2 box; other site
568709009793	G3 box; other site
568709009794	Switch II region; other site
568709009795	G4 box; other site
568709009796	G5 box; other site
568709009797	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
568709009798	Translation-initiation factor 2; Region: IF-2; pfam11987
568709009799	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
568709009800	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
568709009801	NusA N-terminal domain; Region: NusA_N; pfam08529
568709009802	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
568709009803	RNA binding site [nucleotide binding]; other site
568709009804	homodimer interface [polypeptide binding]; other site
568709009805	NusA-like KH domain; Region: KH_5; pfam13184
568709009806	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
568709009807	G-X-X-G motif; other site
568709009808	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
568709009809	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
568709009810	ribosome maturation protein RimP; Reviewed; Region: PRK00092
568709009811	hypothetical protein; Provisional; Region: PRK14641
568709009812	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
568709009813	putative oligomer interface [polypeptide binding]; other site
568709009814	putative RNA binding site [nucleotide binding]; other site
568709009815	argininosuccinate synthase; Validated; Region: PRK05370
568709009816	argininosuccinate synthase; Provisional; Region: PRK13820
568709009817	Domain of unknown function (DUF1963); Region: DUF1963; cl01600
568709009818	Preprotein translocase SecG subunit; Region: SecG; pfam03840
568709009819	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
568709009820	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
568709009821	active site
568709009822	substrate binding site [chemical binding]; other site
568709009823	metal binding site [ion binding]; metal-binding site
568709009824	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
568709009825	dihydropteroate synthase; Region: DHPS; TIGR01496
568709009826	substrate binding pocket [chemical binding]; other site
568709009827	dimer interface [polypeptide binding]; other site
568709009828	inhibitor binding site; inhibition site
568709009829	Transposase IS200 like; Region: Y1_Tnp; pfam01797
568709009830	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
568709009831	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709009832	Walker A motif; other site
568709009833	ATP binding site [chemical binding]; other site
568709009834	Walker B motif; other site
568709009835	arginine finger; other site
568709009836	Peptidase family M41; Region: Peptidase_M41; pfam01434
568709009837	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
568709009838	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709009839	S-adenosylmethionine binding site [chemical binding]; other site
568709009840	RNA-binding protein YhbY; Provisional; Region: PRK10343
568709009841	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
568709009842	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
568709009843	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
568709009844	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
568709009845	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
568709009846	GTPase CgtA; Reviewed; Region: obgE; PRK12298
568709009847	GTP1/OBG; Region: GTP1_OBG; pfam01018
568709009848	Obg GTPase; Region: Obg; cd01898
568709009849	G1 box; other site
568709009850	GTP/Mg2+ binding site [chemical binding]; other site
568709009851	Switch I region; other site
568709009852	G2 box; other site
568709009853	G3 box; other site
568709009854	Switch II region; other site
568709009855	G4 box; other site
568709009856	G5 box; other site
568709009857	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
568709009858	EamA-like transporter family; Region: EamA; pfam00892
568709009859	EamA-like transporter family; Region: EamA; pfam00892
568709009860	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
568709009861	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
568709009862	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
568709009863	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
568709009864	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
568709009865	substrate binding pocket [chemical binding]; other site
568709009866	chain length determination region; other site
568709009867	substrate-Mg2+ binding site; other site
568709009868	catalytic residues [active]
568709009869	aspartate-rich region 1; other site
568709009870	active site lid residues [active]
568709009871	aspartate-rich region 2; other site
568709009872	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
568709009873	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
568709009874	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
568709009875	hinge; other site
568709009876	active site
568709009877	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
568709009878	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
568709009879	anti sigma factor interaction site; other site
568709009880	regulatory phosphorylation site [posttranslational modification]; other site
568709009881	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
568709009882	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
568709009883	mce related protein; Region: MCE; pfam02470
568709009884	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
568709009885	conserved hypothetical integral membrane protein; Region: TIGR00056
568709009886	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
568709009887	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
568709009888	Walker A/P-loop; other site
568709009889	ATP binding site [chemical binding]; other site
568709009890	Q-loop/lid; other site
568709009891	ABC transporter signature motif; other site
568709009892	Walker B; other site
568709009893	D-loop; other site
568709009894	H-loop/switch region; other site
568709009895	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
568709009896	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
568709009897	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
568709009898	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
568709009899	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
568709009900	putative active site [active]
568709009901	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
568709009902	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
568709009903	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
568709009904	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
568709009905	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
568709009906	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
568709009907	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
568709009908	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
568709009909	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
568709009910	Walker A/P-loop; other site
568709009911	ATP binding site [chemical binding]; other site
568709009912	Q-loop/lid; other site
568709009913	ABC transporter signature motif; other site
568709009914	Walker B; other site
568709009915	D-loop; other site
568709009916	H-loop/switch region; other site
568709009917	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
568709009918	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
568709009919	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
568709009920	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
568709009921	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
568709009922	30S subunit binding site; other site
568709009923	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709009924	active site
568709009925	phosphorylation site [posttranslational modification]
568709009926	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
568709009927	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
568709009928	dimerization domain swap beta strand [polypeptide binding]; other site
568709009929	regulatory protein interface [polypeptide binding]; other site
568709009930	active site
568709009931	regulatory phosphorylation site [posttranslational modification]; other site
568709009932	hypothetical protein; Provisional; Region: PRK10345
568709009933	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
568709009934	Transglycosylase; Region: Transgly; cl17702
568709009935	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
568709009936	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
568709009937	conserved cys residue [active]
568709009938	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
568709009939	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
568709009940	putative active site [active]
568709009941	heme pocket [chemical binding]; other site
568709009942	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709009943	dimer interface [polypeptide binding]; other site
568709009944	phosphorylation site [posttranslational modification]
568709009945	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709009946	ATP binding site [chemical binding]; other site
568709009947	Mg2+ binding site [ion binding]; other site
568709009948	G-X-G motif; other site
568709009949	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709009950	active site
568709009951	phosphorylation site [posttranslational modification]
568709009952	intermolecular recognition site; other site
568709009953	dimerization interface [polypeptide binding]; other site
568709009954	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
568709009955	putative binding surface; other site
568709009956	active site
568709009957	radical SAM protein, TIGR01212 family; Region: TIGR01212
568709009958	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709009959	FeS/SAM binding site; other site
568709009960	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
568709009961	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
568709009962	active site
568709009963	dimer interface [polypeptide binding]; other site
568709009964	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
568709009965	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
568709009966	active site
568709009967	FMN binding site [chemical binding]; other site
568709009968	substrate binding site [chemical binding]; other site
568709009969	3Fe-4S cluster binding site [ion binding]; other site
568709009970	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
568709009971	domain interface; other site
568709009972	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
568709009973	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568709009974	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709009975	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
568709009976	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
568709009977	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
568709009978	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
568709009979	Na binding site [ion binding]; other site
568709009980	putative substrate binding site [chemical binding]; other site
568709009981	cytosine deaminase; Provisional; Region: PRK09230
568709009982	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
568709009983	active site
568709009984	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
568709009985	N-acetylmannosamine kinase; Provisional; Region: PRK05082
568709009986	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568709009987	nucleotide binding site [chemical binding]; other site
568709009988	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
568709009989	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
568709009990	putative active site cavity [active]
568709009991	putative sialic acid transporter; Provisional; Region: PRK03893
568709009992	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709009993	putative substrate translocation pore; other site
568709009994	N-acetylneuraminate lyase; Provisional; Region: PRK04147
568709009995	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
568709009996	inhibitor site; inhibition site
568709009997	active site
568709009998	dimer interface [polypeptide binding]; other site
568709009999	catalytic residue [active]
568709010000	transcriptional regulator NanR; Provisional; Region: PRK03837
568709010001	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709010002	DNA-binding site [nucleotide binding]; DNA binding site
568709010003	FCD domain; Region: FCD; pfam07729
568709010004	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
568709010005	stringent starvation protein A; Provisional; Region: sspA; PRK09481
568709010006	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
568709010007	C-terminal domain interface [polypeptide binding]; other site
568709010008	putative GSH binding site (G-site) [chemical binding]; other site
568709010009	dimer interface [polypeptide binding]; other site
568709010010	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
568709010011	dimer interface [polypeptide binding]; other site
568709010012	N-terminal domain interface [polypeptide binding]; other site
568709010013	Family of unknown function (DUF695); Region: DUF695; pfam05117
568709010014	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
568709010015	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
568709010016	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
568709010017	23S rRNA interface [nucleotide binding]; other site
568709010018	L3 interface [polypeptide binding]; other site
568709010019	Predicted ATPase [General function prediction only]; Region: COG1485
568709010020	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
568709010021	hypothetical protein; Provisional; Region: PRK11677
568709010022	serine endoprotease; Provisional; Region: PRK10139
568709010023	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
568709010024	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
568709010025	protein binding site [polypeptide binding]; other site
568709010026	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
568709010027	serine endoprotease; Provisional; Region: PRK10898
568709010028	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
568709010029	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
568709010030	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
568709010031	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
568709010032	oxaloacetate decarboxylase; Provisional; Region: PRK14040
568709010033	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
568709010034	active site
568709010035	catalytic residues [active]
568709010036	metal binding site [ion binding]; metal-binding site
568709010037	homodimer binding site [polypeptide binding]; other site
568709010038	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
568709010039	carboxyltransferase (CT) interaction site; other site
568709010040	biotinylation site [posttranslational modification]; other site
568709010041	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
568709010042	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
568709010043	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
568709010044	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
568709010045	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
568709010046	transmembrane helices; other site
568709010047	Transcriptional regulators [Transcription]; Region: GntR; COG1802
568709010048	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709010049	DNA-binding site [nucleotide binding]; DNA binding site
568709010050	FCD domain; Region: FCD; pfam07729
568709010051	Transcriptional regulators [Transcription]; Region: GntR; COG1802
568709010052	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709010053	DNA-binding site [nucleotide binding]; DNA binding site
568709010054	malate dehydrogenase; Provisional; Region: PRK05086
568709010055	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
568709010056	NAD binding site [chemical binding]; other site
568709010057	dimerization interface [polypeptide binding]; other site
568709010058	Substrate binding site [chemical binding]; other site
568709010059	arginine repressor; Provisional; Region: PRK05066
568709010060	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
568709010061	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
568709010062	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
568709010063	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
568709010064	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
568709010065	RNAase interaction site [polypeptide binding]; other site
568709010066	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
568709010067	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
568709010068	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
568709010069	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
568709010070	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709010071	efflux system membrane protein; Provisional; Region: PRK11594
568709010072	transcriptional regulator; Provisional; Region: PRK10632
568709010073	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709010074	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
568709010075	putative effector binding pocket; other site
568709010076	dimerization interface [polypeptide binding]; other site
568709010077	protease TldD; Provisional; Region: tldD; PRK10735
568709010078	hypothetical protein; Provisional; Region: PRK10899
568709010079	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
568709010080	ribonuclease G; Provisional; Region: PRK11712
568709010081	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
568709010082	homodimer interface [polypeptide binding]; other site
568709010083	oligonucleotide binding site [chemical binding]; other site
568709010084	Maf-like protein; Region: Maf; pfam02545
568709010085	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
568709010086	active site
568709010087	dimer interface [polypeptide binding]; other site
568709010088	rod shape-determining protein MreD; Provisional; Region: PRK11060
568709010089	rod shape-determining protein MreC; Region: mreC; TIGR00219
568709010090	rod shape-determining protein MreC; Region: MreC; pfam04085
568709010091	rod shape-determining protein MreB; Provisional; Region: PRK13927
568709010092	MreB and similar proteins; Region: MreB_like; cd10225
568709010093	nucleotide binding site [chemical binding]; other site
568709010094	Mg binding site [ion binding]; other site
568709010095	putative protofilament interaction site [polypeptide binding]; other site
568709010096	RodZ interaction site [polypeptide binding]; other site
568709010097	regulatory protein CsrD; Provisional; Region: PRK11059
568709010098	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568709010099	metal binding site [ion binding]; metal-binding site
568709010100	active site
568709010101	I-site; other site
568709010102	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709010103	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
568709010104	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
568709010105	NADP binding site [chemical binding]; other site
568709010106	dimer interface [polypeptide binding]; other site
568709010107	TMAO/DMSO reductase; Reviewed; Region: PRK05363
568709010108	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
568709010109	Moco binding site; other site
568709010110	metal coordination site [ion binding]; other site
568709010111	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
568709010112	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
568709010113	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
568709010114	carboxyltransferase (CT) interaction site; other site
568709010115	biotinylation site [posttranslational modification]; other site
568709010116	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
568709010117	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
568709010118	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
568709010119	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
568709010120	hypothetical protein; Provisional; Region: PRK10633
568709010121	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
568709010122	Na binding site [ion binding]; other site
568709010123	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
568709010124	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
568709010125	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
568709010126	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
568709010127	FMN binding site [chemical binding]; other site
568709010128	active site
568709010129	catalytic residues [active]
568709010130	substrate binding site [chemical binding]; other site
568709010131	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
568709010132	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
568709010133	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
568709010134	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709010135	DNA methylase; Region: N6_N4_Mtase; pfam01555
568709010136	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
568709010137	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
568709010138	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
568709010139	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
568709010140	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568709010141	metal binding site [ion binding]; metal-binding site
568709010142	active site
568709010143	I-site; other site
568709010144	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709010145	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
568709010146	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709010147	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
568709010148	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
568709010149	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
568709010150	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709010151	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
568709010152	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
568709010153	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
568709010154	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
568709010155	trimer interface [polypeptide binding]; other site
568709010156	putative metal binding site [ion binding]; other site
568709010157	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
568709010158	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
568709010159	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
568709010160	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
568709010161	shikimate binding site; other site
568709010162	NAD(P) binding site [chemical binding]; other site
568709010163	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
568709010164	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
568709010165	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
568709010166	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
568709010167	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
568709010168	hypothetical protein; Validated; Region: PRK03430
568709010169	hypothetical protein; Provisional; Region: PRK10736
568709010170	DNA protecting protein DprA; Region: dprA; TIGR00732
568709010171	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
568709010172	active site
568709010173	catalytic residues [active]
568709010174	metal binding site [ion binding]; metal-binding site
568709010175	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
568709010176	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
568709010177	putative active site [active]
568709010178	substrate binding site [chemical binding]; other site
568709010179	putative cosubstrate binding site; other site
568709010180	catalytic site [active]
568709010181	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
568709010182	substrate binding site [chemical binding]; other site
568709010183	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
568709010184	putative RNA binding site [nucleotide binding]; other site
568709010185	16S rRNA methyltransferase B; Provisional; Region: PRK10901
568709010186	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709010187	S-adenosylmethionine binding site [chemical binding]; other site
568709010188	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
568709010189	TrkA-N domain; Region: TrkA_N; pfam02254
568709010190	TrkA-C domain; Region: TrkA_C; pfam02080
568709010191	TrkA-N domain; Region: TrkA_N; pfam02254
568709010192	TrkA-C domain; Region: TrkA_C; pfam02080
568709010193	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
568709010194	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
568709010195	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
568709010196	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
568709010197	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
568709010198	DNA binding residues [nucleotide binding]
568709010199	dimer interface [polypeptide binding]; other site
568709010200	metal binding site [ion binding]; metal-binding site
568709010201	hypothetical protein; Provisional; Region: PRK10203
568709010202	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
568709010203	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
568709010204	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
568709010205	alphaNTD homodimer interface [polypeptide binding]; other site
568709010206	alphaNTD - beta interaction site [polypeptide binding]; other site
568709010207	alphaNTD - beta' interaction site [polypeptide binding]; other site
568709010208	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
568709010209	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
568709010210	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
568709010211	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568709010212	RNA binding surface [nucleotide binding]; other site
568709010213	30S ribosomal protein S11; Validated; Region: PRK05309
568709010214	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
568709010215	30S ribosomal protein S13; Region: bact_S13; TIGR03631
568709010216	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
568709010217	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
568709010218	SecY translocase; Region: SecY; pfam00344
568709010219	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
568709010220	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
568709010221	23S rRNA binding site [nucleotide binding]; other site
568709010222	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
568709010223	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
568709010224	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
568709010225	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
568709010226	5S rRNA interface [nucleotide binding]; other site
568709010227	23S rRNA interface [nucleotide binding]; other site
568709010228	L5 interface [polypeptide binding]; other site
568709010229	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
568709010230	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
568709010231	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
568709010232	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
568709010233	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
568709010234	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
568709010235	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
568709010236	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
568709010237	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
568709010238	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
568709010239	RNA binding site [nucleotide binding]; other site
568709010240	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
568709010241	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
568709010242	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
568709010243	23S rRNA interface [nucleotide binding]; other site
568709010244	putative translocon interaction site; other site
568709010245	signal recognition particle (SRP54) interaction site; other site
568709010246	L23 interface [polypeptide binding]; other site
568709010247	trigger factor interaction site; other site
568709010248	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
568709010249	23S rRNA interface [nucleotide binding]; other site
568709010250	5S rRNA interface [nucleotide binding]; other site
568709010251	putative antibiotic binding site [chemical binding]; other site
568709010252	L25 interface [polypeptide binding]; other site
568709010253	L27 interface [polypeptide binding]; other site
568709010254	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
568709010255	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
568709010256	G-X-X-G motif; other site
568709010257	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
568709010258	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
568709010259	protein-rRNA interface [nucleotide binding]; other site
568709010260	putative translocon binding site; other site
568709010261	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
568709010262	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
568709010263	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
568709010264	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
568709010265	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
568709010266	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
568709010267	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
568709010268	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
568709010269	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
568709010270	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
568709010271	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
568709010272	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
568709010273	heme binding site [chemical binding]; other site
568709010274	ferroxidase pore; other site
568709010275	ferroxidase diiron center [ion binding]; other site
568709010276	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
568709010277	elongation factor Tu; Reviewed; Region: PRK00049
568709010278	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
568709010279	G1 box; other site
568709010280	GEF interaction site [polypeptide binding]; other site
568709010281	GTP/Mg2+ binding site [chemical binding]; other site
568709010282	Switch I region; other site
568709010283	G2 box; other site
568709010284	G3 box; other site
568709010285	Switch II region; other site
568709010286	G4 box; other site
568709010287	G5 box; other site
568709010288	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
568709010289	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
568709010290	Antibiotic Binding Site [chemical binding]; other site
568709010291	elongation factor G; Reviewed; Region: PRK00007
568709010292	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
568709010293	G1 box; other site
568709010294	putative GEF interaction site [polypeptide binding]; other site
568709010295	GTP/Mg2+ binding site [chemical binding]; other site
568709010296	Switch I region; other site
568709010297	G2 box; other site
568709010298	G3 box; other site
568709010299	Switch II region; other site
568709010300	G4 box; other site
568709010301	G5 box; other site
568709010302	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
568709010303	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
568709010304	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
568709010305	30S ribosomal protein S7; Validated; Region: PRK05302
568709010306	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
568709010307	S17 interaction site [polypeptide binding]; other site
568709010308	S8 interaction site; other site
568709010309	16S rRNA interaction site [nucleotide binding]; other site
568709010310	streptomycin interaction site [chemical binding]; other site
568709010311	23S rRNA interaction site [nucleotide binding]; other site
568709010312	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
568709010313	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
568709010314	sulfur relay protein TusC; Validated; Region: PRK00211
568709010315	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
568709010316	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
568709010317	YheO-like PAS domain; Region: PAS_6; pfam08348
568709010318	HTH domain; Region: HTH_22; pfam13309
568709010319	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
568709010320	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
568709010321	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
568709010322	phi X174 lysis protein; Provisional; Region: PRK02793
568709010323	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
568709010324	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
568709010325	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
568709010326	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
568709010327	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
568709010328	TrkA-N domain; Region: TrkA_N; pfam02254
568709010329	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
568709010330	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
568709010331	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709010332	Walker A/P-loop; other site
568709010333	ATP binding site [chemical binding]; other site
568709010334	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568709010335	ABC transporter signature motif; other site
568709010336	Walker B; other site
568709010337	D-loop; other site
568709010338	ABC transporter; Region: ABC_tran_2; pfam12848
568709010339	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568709010340	putative monooxygenase; Provisional; Region: PRK11118
568709010341	putative hydrolase; Provisional; Region: PRK10985
568709010342	SAM (Sterile alpha motif ); Region: SAM_superfamily; cl15755
568709010343	hypothetical protein; Provisional; Region: PRK04966
568709010344	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
568709010345	active site
568709010346	hypothetical protein; Provisional; Region: PRK10738
568709010347	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
568709010348	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
568709010349	ligand binding site [chemical binding]; other site
568709010350	flexible hinge region; other site
568709010351	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
568709010352	putative switch regulator; other site
568709010353	non-specific DNA interactions [nucleotide binding]; other site
568709010354	DNA binding site [nucleotide binding]
568709010355	sequence specific DNA binding site [nucleotide binding]; other site
568709010356	putative cAMP binding site [chemical binding]; other site
568709010357	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
568709010358	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
568709010359	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
568709010360	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
568709010361	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
568709010362	inhibitor-cofactor binding pocket; inhibition site
568709010363	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709010364	catalytic residue [active]
568709010365	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
568709010366	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
568709010367	glutamine binding [chemical binding]; other site
568709010368	catalytic triad [active]
568709010369	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
568709010370	cell filamentation protein Fic; Provisional; Region: PRK10347
568709010371	hypothetical protein; Provisional; Region: PRK10204
568709010372	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
568709010373	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
568709010374	substrate binding site [chemical binding]; other site
568709010375	putative transporter; Provisional; Region: PRK03699
568709010376	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709010377	putative substrate translocation pore; other site
568709010378	nitrite reductase subunit NirD; Provisional; Region: PRK14989
568709010379	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709010380	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
568709010381	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
568709010382	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
568709010383	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
568709010384	nitrite transporter NirC; Provisional; Region: PRK11562
568709010385	siroheme synthase; Provisional; Region: cysG; PRK10637
568709010386	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
568709010387	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
568709010388	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
568709010389	active site
568709010390	SAM binding site [chemical binding]; other site
568709010391	homodimer interface [polypeptide binding]; other site
568709010392	Autotransporter beta-domain; Region: Autotransporter; pfam03797
568709010393	Transposase IS200 like; Region: Y1_Tnp; pfam01797
568709010395	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
568709010396	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
568709010397	active site
568709010398	HIGH motif; other site
568709010399	dimer interface [polypeptide binding]; other site
568709010400	KMSKS motif; other site
568709010401	phosphoglycolate phosphatase; Provisional; Region: PRK13222
568709010402	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709010403	motif II; other site
568709010404	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
568709010405	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
568709010406	substrate binding site [chemical binding]; other site
568709010407	hexamer interface [polypeptide binding]; other site
568709010408	metal binding site [ion binding]; metal-binding site
568709010409	DNA adenine methylase; Provisional; Region: PRK10904
568709010410	cell division protein DamX; Validated; Region: PRK10905
568709010411	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
568709010412	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
568709010413	active site
568709010414	dimer interface [polypeptide binding]; other site
568709010415	metal binding site [ion binding]; metal-binding site
568709010416	shikimate kinase; Reviewed; Region: aroK; PRK00131
568709010417	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
568709010418	ADP binding site [chemical binding]; other site
568709010419	magnesium binding site [ion binding]; other site
568709010420	putative shikimate binding site; other site
568709010421	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
568709010422	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
568709010423	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
568709010424	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
568709010425	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
568709010426	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
568709010427	Transglycosylase; Region: Transgly; pfam00912
568709010428	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
568709010429	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
568709010430	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
568709010431	ADP-ribose binding site [chemical binding]; other site
568709010432	dimer interface [polypeptide binding]; other site
568709010433	active site
568709010434	nudix motif; other site
568709010435	metal binding site [ion binding]; metal-binding site
568709010436	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
568709010437	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
568709010438	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709010439	motif II; other site
568709010440	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568709010441	RNA binding surface [nucleotide binding]; other site
568709010442	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
568709010443	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
568709010444	dimerization interface [polypeptide binding]; other site
568709010445	domain crossover interface; other site
568709010446	redox-dependent activation switch; other site
568709010447	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
568709010448	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
568709010449	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
568709010450	active site
568709010451	substrate-binding site [chemical binding]; other site
568709010452	metal-binding site [ion binding]
568709010453	ATP binding site [chemical binding]; other site
568709010454	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
568709010455	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709010456	dimerization interface [polypeptide binding]; other site
568709010457	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709010458	dimer interface [polypeptide binding]; other site
568709010459	phosphorylation site [posttranslational modification]
568709010460	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709010461	ATP binding site [chemical binding]; other site
568709010462	G-X-G motif; other site
568709010463	osmolarity response regulator; Provisional; Region: ompR; PRK09468
568709010464	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709010465	active site
568709010466	phosphorylation site [posttranslational modification]
568709010467	intermolecular recognition site; other site
568709010468	dimerization interface [polypeptide binding]; other site
568709010469	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709010470	DNA binding site [nucleotide binding]
568709010471	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
568709010472	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
568709010473	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
568709010474	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
568709010475	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
568709010476	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
568709010477	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
568709010478	RNA binding site [nucleotide binding]; other site
568709010479	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
568709010480	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
568709010481	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
568709010482	G1 box; other site
568709010483	GTP/Mg2+ binding site [chemical binding]; other site
568709010484	Switch I region; other site
568709010485	G2 box; other site
568709010486	G3 box; other site
568709010487	Switch II region; other site
568709010488	G4 box; other site
568709010489	G5 box; other site
568709010490	Nucleoside recognition; Region: Gate; pfam07670
568709010491	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
568709010492	Nucleoside recognition; Region: Gate; pfam07670
568709010493	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
568709010494	hypothetical protein; Provisional; Region: PRK09956
568709010495	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
568709010496	carboxylesterase BioH; Provisional; Region: PRK10349
568709010497	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
568709010498	DNA utilization protein GntX; Provisional; Region: PRK11595
568709010499	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568709010500	active site
568709010501	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
568709010502	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
568709010503	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
568709010504	high-affinity gluconate transporter; Provisional; Region: PRK14984
568709010505	gluconate transporter; Region: gntP; TIGR00791
568709010506	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
568709010507	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
568709010508	maltodextrin phosphorylase; Provisional; Region: PRK14985
568709010509	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
568709010510	homodimer interface [polypeptide binding]; other site
568709010511	active site pocket [active]
568709010512	transcriptional regulator MalT; Provisional; Region: PRK04841
568709010513	AAA ATPase domain; Region: AAA_16; pfam13191
568709010514	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709010515	DNA binding residues [nucleotide binding]
568709010516	dimerization interface [polypeptide binding]; other site
568709010517	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
568709010518	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
568709010519	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
568709010520	RNA 3' phosphate cyclase domain (class II). These proteins function as RNA cyclase to catalyze the ATP-dependent conversion of 3'-phosphate to a 2'.3'-cyclic phosphodiester at the end of RNA molecule. A conserved catalytic histidine...; Region: RNA_Cyclase_Class_II; cd00874
568709010521	putative active site [active]
568709010522	adenylation catalytic residue [active]
568709010523	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
568709010524	hypothetical protein; Reviewed; Region: PRK09588
568709010525	TROVE domain; Region: TROVE; pfam05731
568709010526	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
568709010527	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
568709010528	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709010529	Walker A motif; other site
568709010530	ATP binding site [chemical binding]; other site
568709010531	Walker B motif; other site
568709010532	arginine finger; other site
568709010533	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709010534	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
568709010535	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709010536	intramembrane serine protease GlpG; Provisional; Region: PRK10907
568709010537	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
568709010538	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
568709010539	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
568709010540	active site residue [active]
568709010541	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
568709010542	hypothetical protein; Provisional; Region: PRK09781
568709010543	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
568709010544	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
568709010545	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
568709010546	dimer interface [polypeptide binding]; other site
568709010547	active site
568709010548	metal binding site [ion binding]; metal-binding site
568709010549	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709010550	D-galactonate transporter; Region: 2A0114; TIGR00893
568709010551	putative substrate translocation pore; other site
568709010552	Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism / Carbohydrate transport and metabolism]; Region: IlvD; COG0129
568709010553	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
568709010554	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
568709010555	inhibitor site; inhibition site
568709010556	active site
568709010557	dimer interface [polypeptide binding]; other site
568709010558	catalytic residue [active]
568709010559	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
568709010560	Transcriptional regulator [Transcription]; Region: IclR; COG1414
568709010561	Bacterial transcriptional regulator; Region: IclR; pfam01614
568709010562	glycogen phosphorylase; Provisional; Region: PRK14986
568709010563	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
568709010564	homodimer interface [polypeptide binding]; other site
568709010565	active site pocket [active]
568709010566	glycogen synthase; Provisional; Region: glgA; PRK00654
568709010567	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
568709010568	ADP-binding pocket [chemical binding]; other site
568709010569	homodimer interface [polypeptide binding]; other site
568709010570	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
568709010571	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
568709010572	ligand binding site; other site
568709010573	oligomer interface; other site
568709010574	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
568709010575	dimer interface [polypeptide binding]; other site
568709010576	N-terminal domain interface [polypeptide binding]; other site
568709010577	sulfate 1 binding site; other site
568709010578	glycogen debranching enzyme; Provisional; Region: PRK03705
568709010579	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
568709010580	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
568709010581	active site
568709010582	catalytic site [active]
568709010583	glycogen branching enzyme; Provisional; Region: PRK05402
568709010584	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
568709010585	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
568709010586	active site
568709010587	catalytic site [active]
568709010588	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
568709010589	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
568709010590	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
568709010591	low affinity gluconate transporter; Provisional; Region: PRK10472
568709010592	gluconate transporter; Region: gntP; TIGR00791
568709010593	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
568709010594	ATP-binding site [chemical binding]; other site
568709010595	Gluconate-6-phosphate binding site [chemical binding]; other site
568709010596	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
568709010597	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709010598	DNA binding site [nucleotide binding]
568709010599	domain linker motif; other site
568709010600	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
568709010601	putative ligand binding site [chemical binding]; other site
568709010602	putative dimerization interface [polypeptide binding]; other site
568709010603	Pirin-related protein [General function prediction only]; Region: COG1741
568709010604	Pirin; Region: Pirin; pfam02678
568709010605	putative oxidoreductase; Provisional; Region: PRK10206
568709010606	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568709010607	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
568709010608	putative acetyltransferase YhhY; Provisional; Region: PRK10140
568709010609	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709010610	Coenzyme A binding pocket [chemical binding]; other site
568709010611	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709010612	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
568709010613	substrate binding site [chemical binding]; other site
568709010614	dimer interface [polypeptide binding]; other site
568709010615	ATP binding site [chemical binding]; other site
568709010616	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
568709010617	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
568709010618	Protein of unknown function, DUF606; Region: DUF606; pfam04657
568709010619	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
568709010620	active site
568709010621	substrate binding pocket [chemical binding]; other site
568709010622	homodimer interaction site [polypeptide binding]; other site
568709010623	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
568709010624	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
568709010625	hypothetical protein; Provisional; Region: PRK10350
568709010626	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
568709010627	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
568709010628	putative active site [active]
568709010629	catalytic site [active]
568709010630	putative metal binding site [ion binding]; other site
568709010631	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
568709010632	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
568709010633	Walker A/P-loop; other site
568709010634	ATP binding site [chemical binding]; other site
568709010635	Q-loop/lid; other site
568709010636	ABC transporter signature motif; other site
568709010637	Walker B; other site
568709010638	D-loop; other site
568709010639	H-loop/switch region; other site
568709010640	TOBE domain; Region: TOBE_2; pfam08402
568709010641	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
568709010642	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709010643	dimer interface [polypeptide binding]; other site
568709010644	conserved gate region; other site
568709010645	ABC-ATPase subunit interface; other site
568709010646	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
568709010647	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709010648	dimer interface [polypeptide binding]; other site
568709010649	conserved gate region; other site
568709010650	putative PBP binding loops; other site
568709010651	ABC-ATPase subunit interface; other site
568709010652	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
568709010653	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
568709010654	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
568709010655	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
568709010656	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
568709010657	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
568709010658	Walker A/P-loop; other site
568709010659	ATP binding site [chemical binding]; other site
568709010660	Q-loop/lid; other site
568709010661	ABC transporter signature motif; other site
568709010662	Walker B; other site
568709010663	D-loop; other site
568709010664	H-loop/switch region; other site
568709010665	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
568709010666	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
568709010667	Walker A/P-loop; other site
568709010668	ATP binding site [chemical binding]; other site
568709010669	Q-loop/lid; other site
568709010670	ABC transporter signature motif; other site
568709010671	Walker B; other site
568709010672	D-loop; other site
568709010673	H-loop/switch region; other site
568709010674	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
568709010675	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
568709010676	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
568709010677	TM-ABC transporter signature motif; other site
568709010678	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
568709010679	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
568709010680	TM-ABC transporter signature motif; other site
568709010681	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
568709010682	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
568709010683	dimerization interface [polypeptide binding]; other site
568709010684	ligand binding site [chemical binding]; other site
568709010685	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
568709010686	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
568709010687	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
568709010688	dimerization interface [polypeptide binding]; other site
568709010689	ligand binding site [chemical binding]; other site
568709010690	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
568709010691	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
568709010692	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
568709010693	DNA binding residues [nucleotide binding]
568709010694	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
568709010695	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
568709010696	cell division protein FtsE; Provisional; Region: PRK10908
568709010697	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709010698	Walker A/P-loop; other site
568709010699	ATP binding site [chemical binding]; other site
568709010700	Q-loop/lid; other site
568709010701	ABC transporter signature motif; other site
568709010702	Walker B; other site
568709010703	D-loop; other site
568709010704	H-loop/switch region; other site
568709010705	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
568709010706	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
568709010707	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
568709010708	P loop; other site
568709010709	GTP binding site [chemical binding]; other site
568709010710	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
568709010711	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709010712	S-adenosylmethionine binding site [chemical binding]; other site
568709010713	hypothetical protein; Provisional; Region: PRK10910
568709010714	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
568709010715	Predicted membrane protein [Function unknown]; Region: COG3714
568709010716	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
568709010717	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
568709010718	metal-binding site [ion binding]
568709010719	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568709010720	Soluble P-type ATPase [General function prediction only]; Region: COG4087
568709010721	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
568709010722	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
568709010723	dimer interface [polypeptide binding]; other site
568709010724	ligand binding site [chemical binding]; other site
568709010725	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709010726	dimerization interface [polypeptide binding]; other site
568709010727	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
568709010728	dimer interface [polypeptide binding]; other site
568709010729	putative CheW interface [polypeptide binding]; other site
568709010730	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
568709010731	CPxP  motif; other site
568709010732	hypothetical protein; Provisional; Region: PRK11212
568709010733	hypothetical protein; Provisional; Region: PRK11615
568709010734	major facilitator superfamily transporter; Provisional; Region: PRK05122
568709010735	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709010736	putative substrate translocation pore; other site
568709010737	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
568709010738	Domain of unknown function DUF20; Region: UPF0118; pfam01594
568709010739	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
568709010740	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
568709010741	nickel responsive regulator; Provisional; Region: PRK02967
568709010742	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
568709010743	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
568709010744	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
568709010745	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568709010746	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
568709010747	Walker A/P-loop; other site
568709010748	ATP binding site [chemical binding]; other site
568709010749	Q-loop/lid; other site
568709010750	ABC transporter signature motif; other site
568709010751	Walker B; other site
568709010752	D-loop; other site
568709010753	H-loop/switch region; other site
568709010754	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
568709010755	Walker A/P-loop; other site
568709010756	ATP binding site [chemical binding]; other site
568709010757	Q-loop/lid; other site
568709010758	ABC transporter signature motif; other site
568709010759	Walker B; other site
568709010760	D-loop; other site
568709010761	H-loop/switch region; other site
568709010762	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
568709010763	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
568709010764	HlyD family secretion protein; Region: HlyD; pfam00529
568709010765	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
568709010766	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709010767	Predicted flavoproteins [General function prediction only]; Region: COG2081
568709010768	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568709010769	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
568709010770	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
568709010771	universal stress protein UspB; Provisional; Region: PRK04960
568709010772	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
568709010773	Ligand Binding Site [chemical binding]; other site
568709010774	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
568709010775	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709010776	putative substrate translocation pore; other site
568709010777	POT family; Region: PTR2; pfam00854
568709010778	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709010779	S-adenosylmethionine binding site [chemical binding]; other site
568709010780	oligopeptidase A; Provisional; Region: PRK10911
568709010781	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
568709010782	active site
568709010783	Zn binding site [ion binding]; other site
568709010784	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
568709010785	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
568709010786	active site
568709010787	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
568709010788	glutathione reductase; Validated; Region: PRK06116
568709010789	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
568709010790	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709010791	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
568709010792	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
568709010793	active site
568709010794	homodimer interface [polypeptide binding]; other site
568709010795	homotetramer interface [polypeptide binding]; other site
568709010796	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
568709010797	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
568709010798	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
568709010799	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709010800	substrate binding site [chemical binding]; other site
568709010801	ATP binding site [chemical binding]; other site
568709010802	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
568709010803	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
568709010804	putative active site [active]
568709010805	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
568709010806	dimer interface [polypeptide binding]; other site
568709010807	active site
568709010808	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
568709010809	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709010810	DNA-binding site [nucleotide binding]; DNA binding site
568709010811	UTRA domain; Region: UTRA; pfam07702
568709010812	trehalase; Provisional; Region: treF; PRK13270
568709010813	Trehalase; Region: Trehalase; pfam01204
568709010814	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
568709010815	catalytic residue [active]
568709010816	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
568709010817	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709010818	DNA binding residues [nucleotide binding]
568709010819	dimerization interface [polypeptide binding]; other site
568709010820	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709010821	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709010822	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
568709010823	putative effector binding pocket; other site
568709010824	putative dimerization interface [polypeptide binding]; other site
568709010825	inner membrane protein YhjD; Region: TIGR00766
568709010826	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709010827	metabolite-proton symporter; Region: 2A0106; TIGR00883
568709010828	putative substrate translocation pore; other site
568709010829	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
568709010830	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
568709010831	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709010832	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709010833	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
568709010834	substrate binding site [chemical binding]; other site
568709010835	ATP binding site [chemical binding]; other site
568709010836	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
568709010837	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
568709010838	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
568709010839	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
568709010840	putative diguanylate cyclase; Provisional; Region: PRK13561
568709010841	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568709010842	metal binding site [ion binding]; metal-binding site
568709010843	active site
568709010844	I-site; other site
568709010845	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709010846	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
568709010847	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
568709010848	TPR motif; other site
568709010849	binding surface
568709010850	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
568709010851	TPR motif; other site
568709010852	binding surface
568709010853	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
568709010854	binding surface
568709010855	TPR motif; other site
568709010856	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
568709010857	endo-1,4-D-glucanase; Provisional; Region: PRK11097
568709010858	cellulose synthase regulator protein; Provisional; Region: PRK11114
568709010859	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
568709010860	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568709010861	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
568709010862	DXD motif; other site
568709010863	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568709010864	PilZ domain; Region: PilZ; pfam07238
568709010865	cell division protein; Provisional; Region: PRK10037
568709010866	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
568709010867	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
568709010868	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
568709010869	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
568709010870	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
568709010871	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
568709010872	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
568709010873	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
568709010874	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
568709010875	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709010876	Walker A/P-loop; other site
568709010877	ATP binding site [chemical binding]; other site
568709010878	Q-loop/lid; other site
568709010879	ABC transporter signature motif; other site
568709010880	Walker B; other site
568709010881	D-loop; other site
568709010882	H-loop/switch region; other site
568709010883	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
568709010884	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
568709010885	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
568709010886	Walker A/P-loop; other site
568709010887	ATP binding site [chemical binding]; other site
568709010888	Q-loop/lid; other site
568709010889	ABC transporter signature motif; other site
568709010890	Walker B; other site
568709010891	D-loop; other site
568709010892	H-loop/switch region; other site
568709010893	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
568709010894	dipeptide transporter; Provisional; Region: PRK10913
568709010895	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
568709010896	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709010897	dimer interface [polypeptide binding]; other site
568709010898	conserved gate region; other site
568709010899	putative PBP binding loops; other site
568709010900	ABC-ATPase subunit interface; other site
568709010901	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
568709010902	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709010903	dimer interface [polypeptide binding]; other site
568709010904	conserved gate region; other site
568709010905	putative PBP binding loops; other site
568709010906	ABC-ATPase subunit interface; other site
568709010907	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
568709010908	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
568709010909	peptide binding site [polypeptide binding]; other site
568709010910	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
568709010911	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
568709010912	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568709010913	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709010914	DNA binding site [nucleotide binding]
568709010915	domain linker motif; other site
568709010916	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
568709010917	putative dimerization interface [polypeptide binding]; other site
568709010918	putative ligand binding site [chemical binding]; other site
568709010919	phosphoethanolamine transferase; Provisional; Region: PRK11560
568709010920	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
568709010921	Sulfatase; Region: Sulfatase; pfam00884
568709010922	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
568709010923	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
568709010924	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
568709010925	PapC N-terminal domain; Region: PapC_N; pfam13954
568709010926	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709010927	PapC C-terminal domain; Region: PapC_C; pfam13953
568709010928	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
568709010929	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709010930	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709010931	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
568709010932	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
568709010933	Methyladenine glycosylase; Region: Adenine_glyco; cl01059
568709010934	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709010935	Coenzyme A binding pocket [chemical binding]; other site
568709010936	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
568709010937	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
568709010938	molybdopterin cofactor binding site [chemical binding]; other site
568709010939	substrate binding site [chemical binding]; other site
568709010940	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
568709010941	molybdopterin cofactor binding site; other site
568709010942	putative outer membrane lipoprotein; Provisional; Region: PRK10510
568709010943	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
568709010944	ligand binding site [chemical binding]; other site
568709010945	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
568709010946	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
568709010947	dimerization interface [polypeptide binding]; other site
568709010948	ligand binding site [chemical binding]; other site
568709010949	NADP binding site [chemical binding]; other site
568709010950	catalytic site [active]
568709010951	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
568709010952	Predicted transcriptional regulator [Transcription]; Region: COG2944
568709010953	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709010954	salt bridge; other site
568709010955	non-specific DNA binding site [nucleotide binding]; other site
568709010956	sequence-specific DNA binding site [nucleotide binding]; other site
568709010957	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
568709010958	DNA-binding site [nucleotide binding]; DNA binding site
568709010959	RNA-binding motif; other site
568709010960	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
568709010961	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
568709010962	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
568709010963	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709010964	Coenzyme A binding pocket [chemical binding]; other site
568709010965	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
568709010966	DALR anticodon binding domain; Region: DALR_1; pfam05746
568709010967	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
568709010968	dimer interface [polypeptide binding]; other site
568709010969	motif 1; other site
568709010970	active site
568709010971	motif 2; other site
568709010972	motif 3; other site
568709010973	YsaB-like lipoprotein; Region: YsaB; pfam13983
568709010974	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
568709010975	Acyltransferase family; Region: Acyl_transf_3; pfam01757
568709010976	Predicted membrane protein [Function unknown]; Region: COG4682
568709010977	yiaA/B two helix domain; Region: YiaAB; cl01759
568709010978	yiaA/B two helix domain; Region: YiaAB; cl01759
568709010979	xylulokinase; Provisional; Region: PRK15027
568709010980	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
568709010981	N- and C-terminal domain interface [polypeptide binding]; other site
568709010982	active site
568709010983	MgATP binding site [chemical binding]; other site
568709010984	catalytic site [active]
568709010985	metal binding site [ion binding]; metal-binding site
568709010986	xylulose binding site [chemical binding]; other site
568709010987	homodimer interface [polypeptide binding]; other site
568709010988	xylose isomerase; Provisional; Region: PRK05474
568709010989	xylose isomerase; Region: xylose_isom_A; TIGR02630
568709010990	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
568709010991	putative dimerization interface [polypeptide binding]; other site
568709010992	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568709010993	putative ligand binding site [chemical binding]; other site
568709010994	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709010995	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568709010996	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709010997	hypothetical protein; Provisional; Region: PRK10356
568709010998	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
568709010999	alpha-amylase; Reviewed; Region: malS; PRK09505
568709011000	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
568709011001	active site
568709011002	catalytic site [active]
568709011003	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
568709011004	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709011005	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709011006	homodimer interface [polypeptide binding]; other site
568709011007	catalytic residue [active]
568709011008	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
568709011009	Transcriptional regulator [Transcription]; Region: IclR; COG1414
568709011010	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
568709011011	Bacterial transcriptional regulator; Region: IclR; pfam01614
568709011012	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
568709011013	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
568709011014	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
568709011015	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
568709011016	DctM-like transporters; Region: DctM; pfam06808
568709011017	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
568709011018	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
568709011019	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
568709011020	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
568709011021	putative N- and C-terminal domain interface [polypeptide binding]; other site
568709011022	putative active site [active]
568709011023	MgATP binding site [chemical binding]; other site
568709011024	catalytic site [active]
568709011025	metal binding site [ion binding]; metal-binding site
568709011026	putative xylulose binding site [chemical binding]; other site
568709011027	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
568709011028	active site
568709011029	dimer interface [polypeptide binding]; other site
568709011030	magnesium binding site [ion binding]; other site
568709011031	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
568709011032	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
568709011033	AP (apurinic/apyrimidinic) site pocket; other site
568709011034	DNA interaction; other site
568709011035	Metal-binding active site; metal-binding site
568709011036	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
568709011037	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
568709011038	intersubunit interface [polypeptide binding]; other site
568709011039	active site
568709011040	Zn2+ binding site [ion binding]; other site
568709011041	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
568709011042	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
568709011043	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709011044	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
568709011045	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
568709011046	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
568709011047	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
568709011048	NAD(P) binding site [chemical binding]; other site
568709011049	catalytic residues [active]
568709011050	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
568709011051	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
568709011052	nucleotide binding site [chemical binding]; other site
568709011053	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
568709011054	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
568709011055	G1 box; other site
568709011056	putative GEF interaction site [polypeptide binding]; other site
568709011057	GTP/Mg2+ binding site [chemical binding]; other site
568709011058	Switch I region; other site
568709011059	G2 box; other site
568709011060	G3 box; other site
568709011061	Switch II region; other site
568709011062	G4 box; other site
568709011063	G5 box; other site
568709011064	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
568709011065	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
568709011066	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
568709011067	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
568709011068	selenocysteine synthase; Provisional; Region: PRK04311
568709011069	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
568709011070	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
568709011071	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568709011072	catalytic residue [active]
568709011073	putative glutathione S-transferase; Provisional; Region: PRK10357
568709011074	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
568709011075	putative C-terminal domain interface [polypeptide binding]; other site
568709011076	putative GSH binding site (G-site) [chemical binding]; other site
568709011077	putative dimer interface [polypeptide binding]; other site
568709011078	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
568709011079	dimer interface [polypeptide binding]; other site
568709011080	N-terminal domain interface [polypeptide binding]; other site
568709011081	putative substrate binding pocket (H-site) [chemical binding]; other site
568709011082	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
568709011083	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
568709011084	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
568709011085	active site
568709011086	P-loop; other site
568709011087	phosphorylation site [posttranslational modification]
568709011088	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709011089	active site
568709011090	phosphorylation site [posttranslational modification]
568709011091	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
568709011092	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
568709011093	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
568709011094	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
568709011095	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
568709011096	hypothetical protein; Provisional; Region: PRK11020
568709011097	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
568709011098	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
568709011099	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
568709011100	trimer interface [polypeptide binding]; other site
568709011101	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
568709011102	Haemagglutinin; Region: HIM; pfam05662
568709011103	Haemagglutinin; Region: HIM; pfam05662
568709011104	YadA-like C-terminal region; Region: YadA; pfam03895
568709011105	L-lactate permease; Provisional; Region: PRK10420
568709011106	glycolate transporter; Provisional; Region: PRK09695
568709011107	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
568709011108	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709011109	DNA-binding site [nucleotide binding]; DNA binding site
568709011110	FCD domain; Region: FCD; pfam07729
568709011111	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
568709011112	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
568709011113	active site
568709011114	substrate binding site [chemical binding]; other site
568709011115	FMN binding site [chemical binding]; other site
568709011116	putative catalytic residues [active]
568709011117	putative rRNA methylase; Provisional; Region: PRK10358
568709011118	Transcriptional regulators [Transcription]; Region: PurR; COG1609
568709011119	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709011120	DNA binding site [nucleotide binding]
568709011121	domain linker motif; other site
568709011122	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
568709011123	putative dimerization interface [polypeptide binding]; other site
568709011124	putative ligand binding site [chemical binding]; other site
568709011125	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
568709011126	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
568709011127	active site pocket [active]
568709011128	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011129	D-galactonate transporter; Region: 2A0114; TIGR00893
568709011130	putative substrate translocation pore; other site
568709011131	serine acetyltransferase; Provisional; Region: cysE; PRK11132
568709011132	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
568709011133	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
568709011134	trimer interface [polypeptide binding]; other site
568709011135	active site
568709011136	substrate binding site [chemical binding]; other site
568709011137	CoA binding site [chemical binding]; other site
568709011138	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
568709011139	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
568709011140	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
568709011141	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
568709011142	SecA binding site; other site
568709011143	Preprotein binding site; other site
568709011144	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
568709011145	GSH binding site [chemical binding]; other site
568709011146	catalytic residues [active]
568709011147	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
568709011148	active site residue [active]
568709011149	phosphoglyceromutase; Provisional; Region: PRK05434
568709011150	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
568709011151	AmiB activator; Provisional; Region: PRK11637
568709011152	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
568709011153	Peptidase family M23; Region: Peptidase_M23; pfam01551
568709011154	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
568709011155	NodB motif; other site
568709011156	putative active site [active]
568709011157	putative catalytic site [active]
568709011158	Zn binding site [ion binding]; other site
568709011159	putative glycosyl transferase; Provisional; Region: PRK10073
568709011160	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
568709011161	active site
568709011162	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
568709011163	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
568709011164	NAD(P) binding site [chemical binding]; other site
568709011165	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
568709011166	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
568709011167	substrate-cofactor binding pocket; other site
568709011168	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709011169	catalytic residue [active]
568709011170	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
568709011171	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
568709011172	NADP binding site [chemical binding]; other site
568709011173	homopentamer interface [polypeptide binding]; other site
568709011174	substrate binding site [chemical binding]; other site
568709011175	active site
568709011176	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
568709011177	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
568709011178	putative active site [active]
568709011179	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
568709011180	Glycosyltransferase family 9 (heptosyltransferase); Region: Glyco_transf_9; pfam01075
568709011181	putative active site [active]
568709011182	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
568709011183	O-antigen ligase RfaL; Provisional; Region: PRK15487
568709011184	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
568709011185	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
568709011186	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; cl17526
568709011187	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
568709011188	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
568709011189	Ligand binding site; other site
568709011190	metal-binding site
568709011191	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
568709011192	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
568709011193	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
568709011194	Ligand binding site; other site
568709011195	metal-binding site
568709011196	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
568709011197	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
568709011198	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
568709011199	putative ADP-binding pocket [chemical binding]; other site
568709011200	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
568709011201	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568709011202	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
568709011203	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
568709011204	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
568709011205	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
568709011206	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
568709011207	putative active site [active]
568709011208	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
568709011209	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
568709011210	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
568709011211	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
568709011212	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
568709011213	active site
568709011214	(T/H)XGH motif; other site
568709011215	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
568709011216	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
568709011217	DNA binding site [nucleotide binding]
568709011218	catalytic residue [active]
568709011219	H2TH interface [polypeptide binding]; other site
568709011220	putative catalytic residues [active]
568709011221	turnover-facilitating residue; other site
568709011222	intercalation triad [nucleotide binding]; other site
568709011223	8OG recognition residue [nucleotide binding]; other site
568709011224	putative reading head residues; other site
568709011225	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
568709011226	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
568709011227	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
568709011228	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
568709011229	hypothetical protein; Reviewed; Region: PRK00024
568709011230	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
568709011231	MPN+ (JAMM) motif; other site
568709011232	Zinc-binding site [ion binding]; other site
568709011233	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
568709011234	Flavoprotein; Region: Flavoprotein; pfam02441
568709011235	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
568709011236	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
568709011237	trimer interface [polypeptide binding]; other site
568709011238	active site
568709011239	division inhibitor protein; Provisional; Region: slmA; PRK09480
568709011240	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709011241	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
568709011242	active site
568709011243	ribonuclease PH; Reviewed; Region: rph; PRK00173
568709011244	Ribonuclease PH; Region: RNase_PH_bact; cd11362
568709011245	hexamer interface [polypeptide binding]; other site
568709011246	active site
568709011247	hypothetical protein; Provisional; Region: PRK11820
568709011248	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
568709011249	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
568709011250	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709011251	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709011252	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
568709011253	dimerization interface [polypeptide binding]; other site
568709011254	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
568709011255	Predicted membrane protein [Function unknown]; Region: COG2860
568709011256	UPF0126 domain; Region: UPF0126; pfam03458
568709011257	UPF0126 domain; Region: UPF0126; pfam03458
568709011258	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
568709011259	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
568709011260	nucleotide binding pocket [chemical binding]; other site
568709011261	K-X-D-G motif; other site
568709011262	catalytic site [active]
568709011263	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
568709011264	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
568709011265	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
568709011266	catalytic site [active]
568709011267	G-X2-G-X-G-K; other site
568709011268	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
568709011269	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
568709011270	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
568709011271	Zn2+ binding site [ion binding]; other site
568709011272	Mg2+ binding site [ion binding]; other site
568709011273	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
568709011274	synthetase active site [active]
568709011275	NTP binding site [chemical binding]; other site
568709011276	metal binding site [ion binding]; metal-binding site
568709011277	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
568709011278	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
568709011279	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
568709011280	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
568709011281	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
568709011282	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
568709011283	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
568709011284	generic binding surface II; other site
568709011285	ssDNA binding site; other site
568709011286	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568709011287	ATP binding site [chemical binding]; other site
568709011288	putative Mg++ binding site [ion binding]; other site
568709011289	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709011290	nucleotide binding region [chemical binding]; other site
568709011291	ATP-binding site [chemical binding]; other site
568709011292	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
568709011293	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
568709011294	AsmA family; Region: AsmA; pfam05170
568709011295	putative alpha-glucosidase; Provisional; Region: PRK10658
568709011296	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
568709011297	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
568709011298	active site
568709011299	homotrimer interface [polypeptide binding]; other site
568709011300	catalytic site [active]
568709011301	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
568709011302	putative transporter; Provisional; Region: PRK11462
568709011303	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
568709011305	Virulence protein [General function prediction only]; Region: COG3943
568709011306	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
568709011307	autotransport protein MisL; Provisional; Region: PRK15313
568709011308	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
568709011309	Autotransporter beta-domain; Region: Autotransporter; pfam03797
568709011310	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
568709011311	DNA binding site [nucleotide binding]
568709011312	Isochorismatase family; Region: Isochorismatase; pfam00857
568709011313	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
568709011314	catalytic triad [active]
568709011315	dimer interface [polypeptide binding]; other site
568709011316	conserved cis-peptide bond; other site
568709011318	magnesium-transporting ATPase; Provisional; Region: PRK15122
568709011319	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
568709011320	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
568709011321	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
568709011322	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709011323	motif II; other site
568709011324	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
568709011325	magnesium transport protein MgtC; Provisional; Region: PRK15385
568709011326	MgtC family; Region: MgtC; pfam02308
568709011327	EamA-like transporter family; Region: EamA; pfam00892
568709011328	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
568709011329	EamA-like transporter family; Region: EamA; pfam00892
568709011330	hypothetical protein; Provisional; Region: PRK09956
568709011331	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
568709011332	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
568709011333	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
568709011334	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
568709011335	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
568709011336	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
568709011337	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
568709011338	active site
568709011339	phosphorylation site [posttranslational modification]
568709011340	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
568709011341	active pocket/dimerization site; other site
568709011342	active site
568709011343	phosphorylation site [posttranslational modification]
568709011344	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
568709011345	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709011346	Walker A motif; other site
568709011347	ATP binding site [chemical binding]; other site
568709011348	Walker B motif; other site
568709011349	arginine finger; other site
568709011350	Transcriptional antiterminator [Transcription]; Region: COG3933
568709011351	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
568709011352	active site
568709011353	active pocket/dimerization site; other site
568709011354	phosphorylation site [posttranslational modification]
568709011355	PRD domain; Region: PRD; pfam00874
568709011356	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
568709011357	beta-galactosidase; Region: BGL; TIGR03356
568709011358	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
568709011359	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
568709011360	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011361	putative substrate translocation pore; other site
568709011362	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
568709011363	Predicted transcriptional regulator [Transcription]; Region: COG2944
568709011364	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709011365	non-specific DNA binding site [nucleotide binding]; other site
568709011366	salt bridge; other site
568709011367	sequence-specific DNA binding site [nucleotide binding]; other site
568709011368	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
568709011369	dimerization domain swap beta strand [polypeptide binding]; other site
568709011370	regulatory protein interface [polypeptide binding]; other site
568709011371	active site
568709011372	regulatory phosphorylation site [posttranslational modification]; other site
568709011373	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
568709011374	intersubunit interface [polypeptide binding]; other site
568709011375	active site
568709011376	zinc binding site [ion binding]; other site
568709011377	Na+ binding site [ion binding]; other site
568709011378	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
568709011379	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
568709011380	putative N- and C-terminal domain interface [polypeptide binding]; other site
568709011381	putative active site [active]
568709011382	putative MgATP binding site [chemical binding]; other site
568709011383	catalytic site [active]
568709011384	metal binding site [ion binding]; metal-binding site
568709011385	putative carbohydrate binding site [chemical binding]; other site
568709011386	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
568709011387	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
568709011388	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
568709011389	active site
568709011390	P-loop; other site
568709011391	phosphorylation site [posttranslational modification]
568709011392	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709011393	active site
568709011394	phosphorylation site [posttranslational modification]
568709011395	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
568709011396	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709011397	DNA-binding site [nucleotide binding]; DNA binding site
568709011398	UTRA domain; Region: UTRA; pfam07702
568709011399	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
568709011400	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
568709011401	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011402	putative substrate translocation pore; other site
568709011403	regulatory protein UhpC; Provisional; Region: PRK11663
568709011404	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011405	putative substrate translocation pore; other site
568709011406	sensory histidine kinase UhpB; Provisional; Region: PRK11644
568709011407	MASE1; Region: MASE1; pfam05231
568709011408	Histidine kinase; Region: HisKA_3; pfam07730
568709011409	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709011410	ATP binding site [chemical binding]; other site
568709011411	Mg2+ binding site [ion binding]; other site
568709011412	G-X-G motif; other site
568709011413	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
568709011414	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709011415	active site
568709011416	phosphorylation site [posttranslational modification]
568709011417	intermolecular recognition site; other site
568709011418	dimerization interface [polypeptide binding]; other site
568709011419	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709011420	DNA binding residues [nucleotide binding]
568709011421	dimerization interface [polypeptide binding]; other site
568709011422	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
568709011423	active site
568709011424	catalytic residues [active]
568709011425	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
568709011426	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011427	putative substrate translocation pore; other site
568709011428	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709011429	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
568709011430	substrate binding site [chemical binding]; other site
568709011431	dimer interface [polypeptide binding]; other site
568709011432	ATP binding site [chemical binding]; other site
568709011433	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
568709011434	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
568709011435	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709011436	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
568709011437	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
568709011438	putative valine binding site [chemical binding]; other site
568709011439	dimer interface [polypeptide binding]; other site
568709011440	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
568709011441	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
568709011442	PYR/PP interface [polypeptide binding]; other site
568709011443	dimer interface [polypeptide binding]; other site
568709011444	TPP binding site [chemical binding]; other site
568709011445	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568709011446	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
568709011447	TPP-binding site [chemical binding]; other site
568709011448	dimer interface [polypeptide binding]; other site
568709011450	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
568709011451	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
568709011452	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
568709011453	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011454	putative substrate translocation pore; other site
568709011455	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
568709011456	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
568709011457	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709011458	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
568709011459	dimerization interface [polypeptide binding]; other site
568709011460	substrate binding pocket [chemical binding]; other site
568709011461	permease DsdX; Provisional; Region: PRK09921
568709011462	gluconate transporter; Region: gntP; TIGR00791
568709011463	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
568709011464	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
568709011465	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
568709011466	catalytic residue [active]
568709011467	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
568709011468	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
568709011469	Domain of unknown function (DUF202); Region: DUF202; pfam02656
568709011470	Predicted membrane protein [Function unknown]; Region: COG2149
568709011471	putative transporter; Validated; Region: PRK03818
568709011472	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
568709011473	TrkA-C domain; Region: TrkA_C; pfam02080
568709011474	TrkA-C domain; Region: TrkA_C; pfam02080
568709011475	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
568709011476	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
568709011477	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
568709011478	putative dimer interface [polypeptide binding]; other site
568709011479	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
568709011480	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
568709011481	putative dimer interface [polypeptide binding]; other site
568709011482	hypothetical protein; Provisional; Region: PRK11616
568709011483	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
568709011484	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
568709011485	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
568709011486	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
568709011487	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709011488	Walker A/P-loop; other site
568709011489	ATP binding site [chemical binding]; other site
568709011490	Q-loop/lid; other site
568709011491	ABC transporter signature motif; other site
568709011492	Walker B; other site
568709011493	D-loop; other site
568709011494	H-loop/switch region; other site
568709011495	Haem-binding domain; Region: Haem_bd; pfam14376
568709011496	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
568709011497	chaperone protein TorD; Validated; Region: torD; PRK04976
568709011498	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
568709011499	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
568709011500	molybdopterin cofactor binding site [chemical binding]; other site
568709011501	substrate binding site [chemical binding]; other site
568709011502	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
568709011503	molybdopterin cofactor binding site; other site
568709011504	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
568709011505	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
568709011506	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
568709011507	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709011508	active site
568709011509	phosphorylation site [posttranslational modification]
568709011510	intermolecular recognition site; other site
568709011511	dimerization interface [polypeptide binding]; other site
568709011512	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709011513	DNA binding site [nucleotide binding]
568709011514	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
568709011515	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
568709011516	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
568709011517	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709011518	dimer interface [polypeptide binding]; other site
568709011519	phosphorylation site [posttranslational modification]
568709011520	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709011521	ATP binding site [chemical binding]; other site
568709011522	Mg2+ binding site [ion binding]; other site
568709011523	G-X-G motif; other site
568709011524	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709011525	active site
568709011526	phosphorylation site [posttranslational modification]
568709011527	intermolecular recognition site; other site
568709011528	dimerization interface [polypeptide binding]; other site
568709011529	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
568709011530	putative binding surface; other site
568709011531	active site
568709011532	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011533	D-galactonate transporter; Region: 2A0114; TIGR00893
568709011534	putative substrate translocation pore; other site
568709011535	galactonate dehydratase; Provisional; Region: PRK14017
568709011536	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
568709011537	putative active site pocket [active]
568709011538	putative metal binding site [ion binding]; other site
568709011539	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
568709011540	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
568709011541	active site
568709011542	intersubunit interface [polypeptide binding]; other site
568709011543	catalytic residue [active]
568709011544	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
568709011545	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
568709011546	Transcriptional regulators [Transcription]; Region: FadR; COG2186
568709011547	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709011548	DNA-binding site [nucleotide binding]; DNA binding site
568709011549	FCD domain; Region: FCD; pfam07729
568709011550	sugar phosphate phosphatase; Provisional; Region: PRK10513
568709011551	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709011552	active site
568709011553	motif I; other site
568709011554	motif II; other site
568709011555	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709011556	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011557	D-galactonate transporter; Region: 2A0114; TIGR00893
568709011558	putative substrate translocation pore; other site
568709011559	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011560	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
568709011561	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
568709011562	active site pocket [active]
568709011563	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709011564	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709011565	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
568709011566	putative dimerization interface [polypeptide binding]; other site
568709011567	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
568709011568	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709011569	Mg2+ binding site [ion binding]; other site
568709011570	G-X-G motif; other site
568709011571	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
568709011572	anchoring element; other site
568709011573	dimer interface [polypeptide binding]; other site
568709011574	ATP binding site [chemical binding]; other site
568709011575	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
568709011576	active site
568709011577	putative metal-binding site [ion binding]; other site
568709011578	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
568709011579	recF protein; Region: recf; TIGR00611
568709011580	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709011581	Walker A/P-loop; other site
568709011582	ATP binding site [chemical binding]; other site
568709011583	Q-loop/lid; other site
568709011584	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709011585	ABC transporter signature motif; other site
568709011586	Walker B; other site
568709011587	D-loop; other site
568709011588	H-loop/switch region; other site
568709011589	DNA polymerase III subunit beta; Validated; Region: PRK05643
568709011590	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
568709011591	putative DNA binding surface [nucleotide binding]; other site
568709011592	dimer interface [polypeptide binding]; other site
568709011593	beta-clamp/clamp loader binding surface; other site
568709011594	beta-clamp/translesion DNA polymerase binding surface; other site
568709011595	DnaA N-terminal domain; Region: DnaA_N; pfam11638
568709011596	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
568709011597	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709011598	Walker A motif; other site
568709011599	ATP binding site [chemical binding]; other site
568709011600	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
568709011601	Walker B motif; other site
568709011602	arginine finger; other site
568709011603	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
568709011604	DnaA box-binding interface [nucleotide binding]; other site
568709011605	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
568709011606	ribonuclease P; Reviewed; Region: rnpA; PRK01732
568709011607	hypothetical protein; Validated; Region: PRK00041
568709011608	membrane protein insertase; Provisional; Region: PRK01318
568709011609	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
568709011610	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
568709011611	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
568709011612	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
568709011613	trmE is a tRNA modification GTPase; Region: trmE; cd04164
568709011614	G1 box; other site
568709011615	GTP/Mg2+ binding site [chemical binding]; other site
568709011616	Switch I region; other site
568709011617	G2 box; other site
568709011618	Switch II region; other site
568709011619	G3 box; other site
568709011620	G4 box; other site
568709011621	G5 box; other site
568709011622	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
568709011623	integrase; Provisional; Region: PRK09692
568709011624	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
568709011625	active site
568709011626	Int/Topo IB signature motif; other site
568709011627	putative transferase, LIC12162 family; Region: o_ant_LIC12162; TIGR04331
568709011628	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
568709011629	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
568709011630	putative active site [active]
568709011631	putative NTP binding site [chemical binding]; other site
568709011632	putative nucleic acid binding site [nucleotide binding]; other site
568709011633	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
568709011634	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011635	putative substrate translocation pore; other site
568709011636	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
568709011637	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709011638	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
568709011639	substrate binding pocket [chemical binding]; other site
568709011640	dimerization interface [polypeptide binding]; other site
568709011641	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
568709011642	Predicted flavoprotein [General function prediction only]; Region: COG0431
568709011643	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
568709011644	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
568709011645	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
568709011646	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709011647	active site
568709011648	motif I; other site
568709011649	motif II; other site
568709011650	transcriptional regulator PhoU; Provisional; Region: PRK11115
568709011651	PhoU domain; Region: PhoU; pfam01895
568709011652	PhoU domain; Region: PhoU; pfam01895
568709011653	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
568709011654	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
568709011655	Walker A/P-loop; other site
568709011656	ATP binding site [chemical binding]; other site
568709011657	Q-loop/lid; other site
568709011658	ABC transporter signature motif; other site
568709011659	Walker B; other site
568709011660	D-loop; other site
568709011661	H-loop/switch region; other site
568709011662	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
568709011663	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709011664	dimer interface [polypeptide binding]; other site
568709011665	conserved gate region; other site
568709011666	putative PBP binding loops; other site
568709011667	ABC-ATPase subunit interface; other site
568709011668	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
568709011669	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709011670	dimer interface [polypeptide binding]; other site
568709011671	conserved gate region; other site
568709011672	putative PBP binding loops; other site
568709011673	ABC-ATPase subunit interface; other site
568709011674	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709011675	substrate binding pocket [chemical binding]; other site
568709011676	membrane-bound complex binding site; other site
568709011677	hinge residues; other site
568709011678	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568709011679	active site
568709011680	P-loop; other site
568709011681	phosphorylation site [posttranslational modification]
568709011682	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
568709011683	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
568709011684	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
568709011685	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
568709011686	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
568709011687	shikimate binding site; other site
568709011688	NAD(P) binding site [chemical binding]; other site
568709011689	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
568709011690	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
568709011691	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
568709011692	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
568709011693	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
568709011694	glutaminase active site [active]
568709011695	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
568709011696	dimer interface [polypeptide binding]; other site
568709011697	active site
568709011698	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
568709011699	dimer interface [polypeptide binding]; other site
568709011700	active site
568709011701	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
568709011702	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
568709011703	Substrate binding site; other site
568709011704	Mg++ binding site; other site
568709011705	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
568709011706	active site
568709011707	substrate binding site [chemical binding]; other site
568709011708	CoA binding site [chemical binding]; other site
568709011709	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
568709011710	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
568709011711	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
568709011712	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
568709011713	gamma subunit interface [polypeptide binding]; other site
568709011714	epsilon subunit interface [polypeptide binding]; other site
568709011715	LBP interface [polypeptide binding]; other site
568709011716	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
568709011717	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
568709011718	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
568709011719	alpha subunit interaction interface [polypeptide binding]; other site
568709011720	Walker A motif; other site
568709011721	ATP binding site [chemical binding]; other site
568709011722	Walker B motif; other site
568709011723	inhibitor binding site; inhibition site
568709011724	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
568709011725	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
568709011726	core domain interface [polypeptide binding]; other site
568709011727	delta subunit interface [polypeptide binding]; other site
568709011728	epsilon subunit interface [polypeptide binding]; other site
568709011729	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
568709011730	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
568709011731	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
568709011732	beta subunit interaction interface [polypeptide binding]; other site
568709011733	Walker A motif; other site
568709011734	ATP binding site [chemical binding]; other site
568709011735	Walker B motif; other site
568709011736	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
568709011737	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
568709011738	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
568709011739	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
568709011740	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
568709011741	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
568709011742	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
568709011743	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
568709011744	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
568709011745	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
568709011746	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709011747	S-adenosylmethionine binding site [chemical binding]; other site
568709011748	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
568709011749	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
568709011750	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
568709011751	FMN-binding protein MioC; Provisional; Region: PRK09004
568709011752	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
568709011753	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568709011754	putative DNA binding site [nucleotide binding]; other site
568709011755	putative Zn2+ binding site [ion binding]; other site
568709011756	AsnC family; Region: AsnC_trans_reg; pfam01037
568709011757	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
568709011758	dimer interface [polypeptide binding]; other site
568709011759	active site
568709011760	hypothetical protein; Provisional; Region: yieM; PRK10997
568709011761	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
568709011762	metal ion-dependent adhesion site (MIDAS); other site
568709011763	regulatory ATPase RavA; Provisional; Region: PRK13531
568709011764	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709011765	Walker A motif; other site
568709011766	ATP binding site [chemical binding]; other site
568709011767	Walker B motif; other site
568709011768	arginine finger; other site
568709011769	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
568709011770	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
568709011771	potassium uptake protein; Region: kup; TIGR00794
568709011772	D-ribose pyranase; Provisional; Region: PRK11797
568709011773	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
568709011774	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
568709011775	Walker A/P-loop; other site
568709011776	ATP binding site [chemical binding]; other site
568709011777	Q-loop/lid; other site
568709011778	ABC transporter signature motif; other site
568709011779	Walker B; other site
568709011780	D-loop; other site
568709011781	H-loop/switch region; other site
568709011782	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
568709011783	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
568709011784	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
568709011785	TM-ABC transporter signature motif; other site
568709011786	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
568709011787	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
568709011788	ligand binding site [chemical binding]; other site
568709011789	dimerization interface [polypeptide binding]; other site
568709011790	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709011791	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
568709011792	substrate binding site [chemical binding]; other site
568709011793	dimer interface [polypeptide binding]; other site
568709011794	ATP binding site [chemical binding]; other site
568709011795	transcriptional repressor RbsR; Provisional; Region: PRK10423
568709011796	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709011797	DNA binding site [nucleotide binding]
568709011798	domain linker motif; other site
568709011799	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
568709011800	dimerization interface [polypeptide binding]; other site
568709011801	ligand binding site [chemical binding]; other site
568709011802	putative transporter; Provisional; Region: PRK10504
568709011803	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011804	putative substrate translocation pore; other site
568709011805	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709011806	Transcriptional regulators [Transcription]; Region: FadR; COG2186
568709011807	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709011808	DNA-binding site [nucleotide binding]; DNA binding site
568709011809	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
568709011810	transcriptional regulator HdfR; Provisional; Region: PRK03601
568709011811	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709011812	LysR substrate binding domain; Region: LysR_substrate; pfam03466
568709011813	dimerization interface [polypeptide binding]; other site
568709011814	hypothetical protein; Provisional; Region: PRK11027
568709011815	putative ATP-dependent protease; Provisional; Region: PRK09862
568709011816	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
568709011817	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709011818	Walker A motif; other site
568709011819	ATP binding site [chemical binding]; other site
568709011820	Walker B motif; other site
568709011821	arginine finger; other site
568709011822	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
568709011823	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
568709011824	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
568709011825	PYR/PP interface [polypeptide binding]; other site
568709011826	dimer interface [polypeptide binding]; other site
568709011827	TPP binding site [chemical binding]; other site
568709011828	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568709011829	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
568709011830	TPP-binding site [chemical binding]; other site
568709011831	dimer interface [polypeptide binding]; other site
568709011832	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
568709011833	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
568709011834	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
568709011835	homodimer interface [polypeptide binding]; other site
568709011836	substrate-cofactor binding pocket; other site
568709011837	catalytic residue [active]
568709011838	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
568709011839	threonine dehydratase; Reviewed; Region: PRK09224
568709011840	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
568709011841	tetramer interface [polypeptide binding]; other site
568709011842	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709011843	catalytic residue [active]
568709011844	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
568709011845	putative Ile/Val binding site [chemical binding]; other site
568709011846	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
568709011847	putative Ile/Val binding site [chemical binding]; other site
568709011848	Phage-related protein [Function unknown]; Region: COG4679
568709011849	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
568709011850	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709011851	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
568709011852	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
568709011853	putative dimerization interface [polypeptide binding]; other site
568709011854	ketol-acid reductoisomerase; Validated; Region: PRK05225
568709011855	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
568709011856	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
568709011857	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
568709011858	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
568709011859	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
568709011860	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
568709011861	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
568709011862	Part of AAA domain; Region: AAA_19; pfam13245
568709011863	Family description; Region: UvrD_C_2; pfam13538
568709011864	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
568709011865	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
568709011866	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
568709011867	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
568709011868	ATP binding site [chemical binding]; other site
568709011869	Mg++ binding site [ion binding]; other site
568709011870	motif III; other site
568709011871	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709011872	nucleotide binding region [chemical binding]; other site
568709011873	ATP-binding site [chemical binding]; other site
568709011874	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
568709011875	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
568709011876	catalytic residues [active]
568709011877	transcription termination factor Rho; Provisional; Region: rho; PRK09376
568709011878	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
568709011879	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
568709011880	RNA binding site [nucleotide binding]; other site
568709011881	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
568709011882	multimer interface [polypeptide binding]; other site
568709011883	Walker A motif; other site
568709011884	ATP binding site [chemical binding]; other site
568709011885	Walker B motif; other site
568709011886	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
568709011887	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
568709011888	Mg++ binding site [ion binding]; other site
568709011889	putative catalytic motif [active]
568709011890	substrate binding site [chemical binding]; other site
568709011891	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
568709011892	Chain length determinant protein; Region: Wzz; pfam02706
568709011893	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
568709011894	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
568709011895	active site
568709011896	homodimer interface [polypeptide binding]; other site
568709011897	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
568709011898	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
568709011899	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
568709011900	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
568709011901	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
568709011902	NAD binding site [chemical binding]; other site
568709011903	substrate binding site [chemical binding]; other site
568709011904	homodimer interface [polypeptide binding]; other site
568709011905	active site
568709011906	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
568709011907	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
568709011908	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
568709011909	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
568709011910	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
568709011911	inhibitor-cofactor binding pocket; inhibition site
568709011912	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709011913	catalytic residue [active]
568709011914	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
568709011915	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
568709011916	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
568709011917	putative common antigen polymerase; Provisional; Region: PRK02975
568709011918	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
568709011919	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
568709011920	putative transport protein YifK; Provisional; Region: PRK10746
568709011921	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
568709011922	HemY protein N-terminus; Region: HemY_N; pfam07219
568709011923	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
568709011924	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
568709011925	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
568709011926	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
568709011927	active site
568709011928	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
568709011929	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
568709011930	domain interfaces; other site
568709011931	active site
568709011932	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
568709011933	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
568709011934	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
568709011935	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
568709011936	putative iron binding site [ion binding]; other site
568709011937	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
568709011938	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
568709011939	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
568709011940	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
568709011941	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
568709011942	hypothetical protein; Provisional; Region: PRK10963
568709011943	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
568709011944	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
568709011945	active site
568709011946	Int/Topo IB signature motif; other site
568709011947	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
568709011948	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709011949	motif II; other site
568709011950	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
568709011951	Part of AAA domain; Region: AAA_19; pfam13245
568709011952	Family description; Region: UvrD_C_2; pfam13538
568709011953	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
568709011954	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
568709011955	Cl binding site [ion binding]; other site
568709011956	oligomer interface [polypeptide binding]; other site
568709011957	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
568709011958	hypothetical protein; Provisional; Region: PRK11371
568709011959	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
568709011960	EamA-like transporter family; Region: EamA; cl17759
568709011961	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
568709011962	CoenzymeA binding site [chemical binding]; other site
568709011963	subunit interaction site [polypeptide binding]; other site
568709011964	PHB binding site; other site
568709011965	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
568709011966	dimerization interface [polypeptide binding]; other site
568709011967	substrate binding site [chemical binding]; other site
568709011968	active site
568709011969	calcium binding site [ion binding]; other site
568709011970	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
568709011971	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568709011972	ATP binding site [chemical binding]; other site
568709011973	putative Mg++ binding site [ion binding]; other site
568709011974	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
568709011975	nucleotide binding region [chemical binding]; other site
568709011976	ATP-binding site [chemical binding]; other site
568709011977	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
568709011978	Helicase and RNase D C-terminal; Region: HRDC; smart00341
568709011979	threonine efflux system; Provisional; Region: PRK10229
568709011980	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
568709011981	lysophospholipase L2; Provisional; Region: PRK10749
568709011982	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
568709011983	putative hydrolase; Provisional; Region: PRK10976
568709011984	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709011985	active site
568709011986	motif I; other site
568709011987	motif II; other site
568709011988	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709011989	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
568709011990	EamA-like transporter family; Region: EamA; pfam00892
568709011991	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
568709011992	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709011993	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
568709011994	putative dimerization interface [polypeptide binding]; other site
568709011995	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
568709011996	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
568709011997	THF binding site; other site
568709011998	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
568709011999	substrate binding site [chemical binding]; other site
568709012000	THF binding site; other site
568709012001	zinc-binding site [ion binding]; other site
568709012002	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
568709012003	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709012004	FeS/SAM binding site; other site
568709012005	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
568709012006	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
568709012007	uridine phosphorylase; Provisional; Region: PRK11178
568709012008	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
568709012009	DNA recombination protein RmuC; Provisional; Region: PRK10361
568709012010	RmuC family; Region: RmuC; pfam02646
568709012011	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
568709012012	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709012013	S-adenosylmethionine binding site [chemical binding]; other site
568709012014	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
568709012015	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
568709012016	SCP-2 sterol transfer family; Region: SCP2; pfam02036
568709012017	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
568709012018	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
568709012019	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
568709012020	sec-independent translocase; Provisional; Region: PRK01770
568709012021	sec-independent translocase; Provisional; Region: tatB; PRK00404
568709012022	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
568709012023	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
568709012024	active site
568709012025	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
568709012026	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
568709012027	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
568709012028	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
568709012029	FMN reductase; Validated; Region: fre; PRK08051
568709012030	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
568709012031	FAD binding pocket [chemical binding]; other site
568709012032	FAD binding motif [chemical binding]; other site
568709012033	phosphate binding motif [ion binding]; other site
568709012034	beta-alpha-beta structure motif; other site
568709012035	NAD binding pocket [chemical binding]; other site
568709012036	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
568709012037	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
568709012038	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
568709012039	dimer interface [polypeptide binding]; other site
568709012040	active site
568709012041	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
568709012042	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
568709012043	substrate binding site [chemical binding]; other site
568709012044	oxyanion hole (OAH) forming residues; other site
568709012045	trimer interface [polypeptide binding]; other site
568709012046	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
568709012047	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
568709012048	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
568709012049	proline dipeptidase; Provisional; Region: PRK13607
568709012050	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
568709012051	active site
568709012052	hypothetical protein; Provisional; Region: PRK11568
568709012053	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
568709012054	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
568709012055	potassium transporter; Provisional; Region: PRK10750
568709012056	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
568709012057	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
568709012058	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
568709012059	Walker A motif; other site
568709012060	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
568709012061	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
568709012062	GTP binding site; other site
568709012063	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
568709012064	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
568709012065	serine/threonine protein kinase; Provisional; Region: PRK11768
568709012066	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
568709012067	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
568709012068	catalytic residues [active]
568709012069	hinge region; other site
568709012070	alpha helical domain; other site
568709012071	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
568709012072	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
568709012073	putative acyl-acceptor binding pocket; other site
568709012074	DNA polymerase I; Provisional; Region: PRK05755
568709012075	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
568709012076	active site
568709012077	metal binding site 1 [ion binding]; metal-binding site
568709012078	putative 5' ssDNA interaction site; other site
568709012079	metal binding site 3; metal-binding site
568709012080	metal binding site 2 [ion binding]; metal-binding site
568709012081	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
568709012082	putative DNA binding site [nucleotide binding]; other site
568709012083	putative metal binding site [ion binding]; other site
568709012084	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
568709012085	active site
568709012086	catalytic site [active]
568709012087	substrate binding site [chemical binding]; other site
568709012088	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
568709012089	active site
568709012090	DNA binding site [nucleotide binding]
568709012091	catalytic site [active]
568709012092	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
568709012093	G1 box; other site
568709012094	GTP/Mg2+ binding site [chemical binding]; other site
568709012095	Switch I region; other site
568709012096	G2 box; other site
568709012097	G3 box; other site
568709012098	Switch II region; other site
568709012099	G4 box; other site
568709012100	G5 box; other site
568709012101	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
568709012102	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
568709012103	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709012104	FeS/SAM binding site; other site
568709012105	HemN C-terminal domain; Region: HemN_C; pfam06969
568709012106	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
568709012107	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709012108	active site
568709012109	phosphorylation site [posttranslational modification]
568709012110	intermolecular recognition site; other site
568709012111	dimerization interface [polypeptide binding]; other site
568709012112	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709012113	Walker A motif; other site
568709012114	ATP binding site [chemical binding]; other site
568709012115	Walker B motif; other site
568709012116	arginine finger; other site
568709012117	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
568709012118	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
568709012119	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
568709012120	putative active site [active]
568709012121	heme pocket [chemical binding]; other site
568709012122	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709012123	dimer interface [polypeptide binding]; other site
568709012124	phosphorylation site [posttranslational modification]
568709012125	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709012126	ATP binding site [chemical binding]; other site
568709012127	Mg2+ binding site [ion binding]; other site
568709012128	G-X-G motif; other site
568709012129	glutamine synthetase; Provisional; Region: glnA; PRK09469
568709012130	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
568709012131	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
568709012132	GTP-binding protein; Provisional; Region: PRK10218
568709012133	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
568709012134	G1 box; other site
568709012135	putative GEF interaction site [polypeptide binding]; other site
568709012136	GTP/Mg2+ binding site [chemical binding]; other site
568709012137	Switch I region; other site
568709012138	G2 box; other site
568709012139	G3 box; other site
568709012140	Switch II region; other site
568709012141	G4 box; other site
568709012142	G5 box; other site
568709012143	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
568709012144	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
568709012145	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709012146	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
568709012147	active site
568709012148	motif I; other site
568709012149	motif II; other site
568709012150	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709012151	coproporphyrinogen III oxidase; Validated; Region: PRK08208
568709012152	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709012153	FeS/SAM binding site; other site
568709012154	HemN C-terminal domain; Region: HemN_C; pfam06969
568709012155	Sulfatase; Region: Sulfatase; cl17466
568709012156	outer membrane porin L; Provisional; Region: ompL; PRK09980
568709012157	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
568709012158	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709012159	putative substrate translocation pore; other site
568709012160	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
568709012161	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
568709012162	alpha-glucosidase; Provisional; Region: PRK10426
568709012163	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
568709012164	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
568709012165	putative active site [active]
568709012166	putative catalytic site [active]
568709012167	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
568709012168	active site
568709012169	catalytic residues [active]
568709012170	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
568709012171	dimerization interface [polypeptide binding]; other site
568709012172	putative active cleft [active]
568709012173	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
568709012174	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
568709012175	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
568709012176	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709012177	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
568709012178	substrate binding site [chemical binding]; other site
568709012179	ATP binding site [chemical binding]; other site
568709012180	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
568709012181	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
568709012182	putative DNA binding site [nucleotide binding]; other site
568709012183	putative Zn2+ binding site [ion binding]; other site
568709012184	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709012185	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
568709012186	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709012187	motif II; other site
568709012188	hypothetical protein; Reviewed; Region: PRK01637
568709012189	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
568709012190	putative active site [active]
568709012191	dimerization interface [polypeptide binding]; other site
568709012192	putative tRNAtyr binding site [nucleotide binding]; other site
568709012193	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709012194	Coenzyme A binding pocket [chemical binding]; other site
568709012195	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
568709012196	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709012197	non-specific DNA binding site [nucleotide binding]; other site
568709012198	salt bridge; other site
568709012199	sequence-specific DNA binding site [nucleotide binding]; other site
568709012200	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
568709012201	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
568709012202	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
568709012203	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
568709012204	Predicted transcriptional regulator [Transcription]; Region: COG2944
568709012205	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709012206	non-specific DNA binding site [nucleotide binding]; other site
568709012207	salt bridge; other site
568709012208	sequence-specific DNA binding site [nucleotide binding]; other site
568709012209	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
568709012210	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
568709012211	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
568709012212	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
568709012213	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
568709012214	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
568709012215	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709012216	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
568709012217	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
568709012218	molybdopterin cofactor binding site; other site
568709012219	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709012220	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
568709012221	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
568709012222	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
568709012223	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
568709012224	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
568709012225	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
568709012226	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709012227	non-specific DNA binding site [nucleotide binding]; other site
568709012228	salt bridge; other site
568709012229	sequence-specific DNA binding site [nucleotide binding]; other site
568709012230	Cupin domain; Region: Cupin_2; cl17218
568709012231	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
568709012232	lactaldehyde reductase; Region: lactal_redase; TIGR02638
568709012233	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
568709012234	dimer interface [polypeptide binding]; other site
568709012235	active site
568709012236	metal binding site [ion binding]; metal-binding site
568709012237	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
568709012238	intersubunit interface [polypeptide binding]; other site
568709012239	active site
568709012240	Zn2+ binding site [ion binding]; other site
568709012241	L-rhamnose isomerase; Provisional; Region: PRK01076
568709012242	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
568709012243	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
568709012244	N- and C-terminal domain interface [polypeptide binding]; other site
568709012245	active site
568709012246	putative catalytic site [active]
568709012247	metal binding site [ion binding]; metal-binding site
568709012248	ATP binding site [chemical binding]; other site
568709012249	rhamnulokinase; Provisional; Region: rhaB; PRK10640
568709012250	carbohydrate binding site [chemical binding]; other site
568709012251	transcriptional activator RhaS; Provisional; Region: PRK13503
568709012252	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
568709012253	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709012254	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709012255	transcriptional activator RhaR; Provisional; Region: PRK13502
568709012256	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
568709012257	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709012258	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
568709012259	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
568709012260	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
568709012261	DctM-like transporters; Region: DctM; pfam06808
568709012262	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
568709012263	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
568709012264	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
568709012265	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
568709012266	superoxide dismutase; Provisional; Region: PRK10925
568709012267	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
568709012268	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
568709012269	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
568709012270	MOSC domain; Region: MOSC; pfam03473
568709012271	3-alpha domain; Region: 3-alpha; pfam03475
568709012272	SnoaL-like domain; Region: SnoaL_2; pfam12680
568709012273	two-component sensor protein; Provisional; Region: cpxA; PRK09470
568709012274	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709012275	dimerization interface [polypeptide binding]; other site
568709012276	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709012277	dimer interface [polypeptide binding]; other site
568709012278	phosphorylation site [posttranslational modification]
568709012279	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709012280	ATP binding site [chemical binding]; other site
568709012281	Mg2+ binding site [ion binding]; other site
568709012282	G-X-G motif; other site
568709012283	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
568709012284	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709012285	active site
568709012286	intermolecular recognition site; other site
568709012287	dimerization interface [polypeptide binding]; other site
568709012288	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709012289	DNA binding site [nucleotide binding]
568709012290	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
568709012291	dimer interface [polypeptide binding]; other site
568709012292	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
568709012293	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
568709012294	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
568709012295	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
568709012296	active site
568709012297	ADP/pyrophosphate binding site [chemical binding]; other site
568709012298	dimerization interface [polypeptide binding]; other site
568709012299	allosteric effector site; other site
568709012300	fructose-1,6-bisphosphate binding site; other site
568709012301	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
568709012302	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709012303	substrate binding pocket [chemical binding]; other site
568709012304	membrane-bound complex binding site; other site
568709012305	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
568709012306	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
568709012307	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
568709012308	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709012309	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
568709012310	putative substrate binding site [chemical binding]; other site
568709012311	putative ATP binding site [chemical binding]; other site
568709012312	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
568709012313	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
568709012314	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709012315	DNA-binding site [nucleotide binding]; DNA binding site
568709012316	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
568709012317	UTRA domain; Region: UTRA; pfam07702
568709012318	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
568709012319	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
568709012320	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
568709012321	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
568709012322	putative N- and C-terminal domain interface [polypeptide binding]; other site
568709012323	putative active site [active]
568709012324	putative MgATP binding site [chemical binding]; other site
568709012325	catalytic site [active]
568709012326	metal binding site [ion binding]; metal-binding site
568709012327	putative carbohydrate binding site [chemical binding]; other site
568709012328	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
568709012329	transcriptional regulator LsrR; Provisional; Region: PRK15418
568709012330	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
568709012331	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
568709012332	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
568709012333	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
568709012334	Walker A/P-loop; other site
568709012335	ATP binding site [chemical binding]; other site
568709012336	Q-loop/lid; other site
568709012337	ABC transporter signature motif; other site
568709012338	Walker B; other site
568709012339	D-loop; other site
568709012340	H-loop/switch region; other site
568709012341	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
568709012342	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
568709012343	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
568709012344	TM-ABC transporter signature motif; other site
568709012345	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
568709012346	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
568709012347	TM-ABC transporter signature motif; other site
568709012348	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
568709012349	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
568709012350	ligand binding site [chemical binding]; other site
568709012351	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
568709012352	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
568709012353	putative active site; other site
568709012354	catalytic residue [active]
568709012355	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
568709012356	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
568709012357	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
568709012358	substrate binding site [chemical binding]; other site
568709012359	hexamer interface [polypeptide binding]; other site
568709012360	metal binding site [ion binding]; metal-binding site
568709012361	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
568709012362	triosephosphate isomerase; Provisional; Region: PRK14567
568709012363	substrate binding site [chemical binding]; other site
568709012364	dimer interface [polypeptide binding]; other site
568709012365	catalytic triad [active]
568709012366	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
568709012367	Predicted membrane protein [Function unknown]; Region: COG3152
568709012368	ferredoxin-NADP reductase; Provisional; Region: PRK10926
568709012369	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
568709012370	FAD binding pocket [chemical binding]; other site
568709012371	FAD binding motif [chemical binding]; other site
568709012372	phosphate binding motif [ion binding]; other site
568709012373	beta-alpha-beta structure motif; other site
568709012374	NAD binding pocket [chemical binding]; other site
568709012375	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
568709012376	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
568709012377	putative active site [active]
568709012378	glycerol kinase; Provisional; Region: glpK; PRK00047
568709012379	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
568709012380	N- and C-terminal domain interface [polypeptide binding]; other site
568709012381	active site
568709012382	MgATP binding site [chemical binding]; other site
568709012383	catalytic site [active]
568709012384	metal binding site [ion binding]; metal-binding site
568709012385	glycerol binding site [chemical binding]; other site
568709012386	homotetramer interface [polypeptide binding]; other site
568709012387	homodimer interface [polypeptide binding]; other site
568709012388	FBP binding site [chemical binding]; other site
568709012389	protein IIAGlc interface [polypeptide binding]; other site
568709012390	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
568709012391	amphipathic channel; other site
568709012392	Asn-Pro-Ala signature motifs; other site
568709012393	septal ring assembly protein ZapB; Provisional; Region: PRK15422
568709012394	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
568709012395	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
568709012396	UbiA prenyltransferase family; Region: UbiA; pfam01040
568709012397	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
568709012398	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709012399	Walker A motif; other site
568709012400	ATP binding site [chemical binding]; other site
568709012401	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
568709012402	Walker B motif; other site
568709012403	arginine finger; other site
568709012404	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
568709012405	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
568709012406	active site
568709012407	HslU subunit interaction site [polypeptide binding]; other site
568709012408	essential cell division protein FtsN; Provisional; Region: PRK10927
568709012409	cell division protein FtsN; Provisional; Region: PRK12757
568709012410	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709012411	DNA binding site [nucleotide binding]
568709012412	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
568709012413	domain linker motif; other site
568709012414	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
568709012415	dimerization interface [polypeptide binding]; other site
568709012416	ligand binding site [chemical binding]; other site
568709012417	primosome assembly protein PriA; Validated; Region: PRK05580
568709012418	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568709012419	ATP binding site [chemical binding]; other site
568709012420	putative Mg++ binding site [ion binding]; other site
568709012421	helicase superfamily c-terminal domain; Region: HELICc; smart00490
568709012422	ATP-binding site [chemical binding]; other site
568709012423	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
568709012424	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
568709012425	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
568709012426	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
568709012427	dimerization interface [polypeptide binding]; other site
568709012428	DNA binding site [nucleotide binding]
568709012429	corepressor binding sites; other site
568709012430	cystathionine gamma-synthase; Provisional; Region: PRK08045
568709012431	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
568709012432	homodimer interface [polypeptide binding]; other site
568709012433	substrate-cofactor binding pocket; other site
568709012434	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709012435	catalytic residue [active]
568709012436	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
568709012437	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
568709012438	putative catalytic residues [active]
568709012439	putative nucleotide binding site [chemical binding]; other site
568709012440	putative aspartate binding site [chemical binding]; other site
568709012441	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
568709012442	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
568709012443	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
568709012444	Conserved TM helix; Region: TM_helix; pfam05552
568709012445	Mechanosensitive ion channel; Region: MS_channel; pfam00924
568709012446	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
568709012447	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
568709012448	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
568709012449	active site
568709012450	metal binding site [ion binding]; metal-binding site
568709012451	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
568709012452	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
568709012453	FAD binding site [chemical binding]; other site
568709012454	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
568709012455	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
568709012456	heme binding site [chemical binding]; other site
568709012457	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
568709012458	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
568709012459	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
568709012460	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
568709012461	dimer interface [polypeptide binding]; other site
568709012462	active site
568709012463	metal binding site [ion binding]; metal-binding site
568709012464	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
568709012465	active site
568709012466	intersubunit interactions; other site
568709012467	catalytic residue [active]
568709012468	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
568709012469	dimerization domain swap beta strand [polypeptide binding]; other site
568709012470	regulatory protein interface [polypeptide binding]; other site
568709012471	active site
568709012472	regulatory phosphorylation site [posttranslational modification]; other site
568709012473	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
568709012474	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
568709012475	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
568709012476	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
568709012477	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709012478	active site
568709012479	phosphorylation site [posttranslational modification]
568709012480	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
568709012481	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
568709012482	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568709012483	active site
568709012484	P-loop; other site
568709012485	phosphorylation site [posttranslational modification]
568709012486	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
568709012487	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
568709012488	dimer interface [polypeptide binding]; other site
568709012489	active site
568709012490	glycine loop; other site
568709012491	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709012492	FeS/SAM binding site; other site
568709012493	pyruvate formate lyase II activase; Provisional; Region: PRK10076
568709012494	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
568709012495	active site
568709012496	P-loop; other site
568709012497	phosphorylation site [posttranslational modification]
568709012498	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568709012499	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709012500	hypothetical protein; Provisional; Region: PRK10649
568709012501	Sulfatase; Region: Sulfatase; pfam00884
568709012502	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
568709012503	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
568709012504	acetylornithine deacetylase; Provisional; Region: PRK05111
568709012505	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
568709012506	metal binding site [ion binding]; metal-binding site
568709012507	putative dimer interface [polypeptide binding]; other site
568709012508	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
568709012509	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
568709012510	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
568709012511	nucleotide binding site [chemical binding]; other site
568709012512	N-acetyl-L-glutamate binding site [chemical binding]; other site
568709012513	argininosuccinate lyase; Provisional; Region: PRK04833
568709012514	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
568709012515	active sites [active]
568709012516	tetramer interface [polypeptide binding]; other site
568709012517	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
568709012518	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709012519	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
568709012520	dimerization interface [polypeptide binding]; other site
568709012521	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
568709012522	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
568709012523	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
568709012524	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
568709012525	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709012526	hypothetical protein; Provisional; Region: PRK11056
568709012527	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
568709012528	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
568709012529	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709012530	S-adenosylmethionine binding site [chemical binding]; other site
568709012531	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
568709012532	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
568709012533	N-terminal plug; other site
568709012534	ligand-binding site [chemical binding]; other site
568709012535	glutamate racemase; Provisional; Region: PRK00865
568709012536	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
568709012537	FAD binding domain; Region: FAD_binding_4; pfam01565
568709012538	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
568709012539	Biotin operon repressor [Transcription]; Region: BirA; COG1654
568709012540	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
568709012541	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
568709012542	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
568709012543	pantothenate kinase; Provisional; Region: PRK05439
568709012544	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
568709012545	ATP-binding site [chemical binding]; other site
568709012546	CoA-binding site [chemical binding]; other site
568709012547	Mg2+-binding site [ion binding]; other site
568709012548	elongation factor Tu; Reviewed; Region: PRK00049
568709012549	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
568709012550	G1 box; other site
568709012551	GEF interaction site [polypeptide binding]; other site
568709012552	GTP/Mg2+ binding site [chemical binding]; other site
568709012553	Switch I region; other site
568709012554	G2 box; other site
568709012555	G3 box; other site
568709012556	Switch II region; other site
568709012557	G4 box; other site
568709012558	G5 box; other site
568709012559	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
568709012560	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
568709012561	Antibiotic Binding Site [chemical binding]; other site
568709012562	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
568709012563	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
568709012564	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
568709012565	putative homodimer interface [polypeptide binding]; other site
568709012566	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
568709012567	heterodimer interface [polypeptide binding]; other site
568709012568	homodimer interface [polypeptide binding]; other site
568709012569	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
568709012570	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
568709012571	23S rRNA interface [nucleotide binding]; other site
568709012572	L7/L12 interface [polypeptide binding]; other site
568709012573	putative thiostrepton binding site; other site
568709012574	L25 interface [polypeptide binding]; other site
568709012575	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
568709012576	mRNA/rRNA interface [nucleotide binding]; other site
568709012577	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
568709012578	23S rRNA interface [nucleotide binding]; other site
568709012579	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
568709012580	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
568709012581	core dimer interface [polypeptide binding]; other site
568709012582	peripheral dimer interface [polypeptide binding]; other site
568709012583	L10 interface [polypeptide binding]; other site
568709012584	L11 interface [polypeptide binding]; other site
568709012585	putative EF-Tu interaction site [polypeptide binding]; other site
568709012586	putative EF-G interaction site [polypeptide binding]; other site
568709012587	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
568709012588	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
568709012589	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
568709012590	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
568709012591	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
568709012592	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
568709012593	RPB3 interaction site [polypeptide binding]; other site
568709012594	RPB1 interaction site [polypeptide binding]; other site
568709012595	RPB11 interaction site [polypeptide binding]; other site
568709012596	RPB10 interaction site [polypeptide binding]; other site
568709012597	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
568709012598	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
568709012599	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
568709012600	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
568709012601	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
568709012602	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
568709012603	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
568709012604	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
568709012605	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
568709012606	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
568709012607	DNA binding site [nucleotide binding]
568709012608	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
568709012609	type III secretion system protein; Provisional; Region: PRK15384
568709012610	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
568709012611	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
568709012612	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709012613	FeS/SAM binding site; other site
568709012614	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
568709012615	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
568709012616	ThiS interaction site; other site
568709012617	putative active site [active]
568709012618	tetramer interface [polypeptide binding]; other site
568709012619	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
568709012620	thiS-thiF/thiG interaction site; other site
568709012621	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
568709012622	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
568709012623	ATP binding site [chemical binding]; other site
568709012624	substrate interface [chemical binding]; other site
568709012625	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
568709012626	thiamine phosphate binding site [chemical binding]; other site
568709012627	active site
568709012628	pyrophosphate binding site [ion binding]; other site
568709012629	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
568709012630	ThiC-associated domain; Region: ThiC-associated; pfam13667
568709012631	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
568709012632	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
568709012633	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
568709012634	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
568709012635	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
568709012636	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
568709012637	putative NADH binding site [chemical binding]; other site
568709012638	putative active site [active]
568709012639	nudix motif; other site
568709012640	putative metal binding site [ion binding]; other site
568709012641	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
568709012642	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
568709012643	substrate binding site [chemical binding]; other site
568709012644	active site
568709012645	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
568709012646	Active_site [active]
568709012647	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
568709012648	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
568709012649	IHF dimer interface [polypeptide binding]; other site
568709012650	IHF - DNA interface [nucleotide binding]; other site
568709012651	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
568709012652	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
568709012653	dimer interface [polypeptide binding]; other site
568709012654	sensor protein ZraS; Provisional; Region: PRK10364
568709012655	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709012656	dimer interface [polypeptide binding]; other site
568709012657	phosphorylation site [posttranslational modification]
568709012658	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709012659	ATP binding site [chemical binding]; other site
568709012660	Mg2+ binding site [ion binding]; other site
568709012661	G-X-G motif; other site
568709012662	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
568709012663	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709012664	active site
568709012665	phosphorylation site [posttranslational modification]
568709012666	intermolecular recognition site; other site
568709012667	dimerization interface [polypeptide binding]; other site
568709012668	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709012669	Walker A motif; other site
568709012670	ATP binding site [chemical binding]; other site
568709012671	Walker B motif; other site
568709012672	arginine finger; other site
568709012673	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
568709012674	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
568709012675	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
568709012676	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
568709012677	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
568709012678	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
568709012679	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
568709012680	purine monophosphate binding site [chemical binding]; other site
568709012681	dimer interface [polypeptide binding]; other site
568709012682	putative catalytic residues [active]
568709012683	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
568709012684	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
568709012685	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709012686	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
568709012687	Coenzyme A binding pocket [chemical binding]; other site
568709012688	homoserine O-succinyltransferase; Provisional; Region: PRK05368
568709012689	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
568709012690	proposed active site lysine [active]
568709012691	conserved cys residue [active]
568709012692	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
568709012693	malate synthase A; Region: malate_syn_A; TIGR01344
568709012694	active site
568709012695	isocitrate lyase; Provisional; Region: PRK15063
568709012696	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
568709012697	tetramer interface [polypeptide binding]; other site
568709012698	active site
568709012699	Mg2+/Mn2+ binding site [ion binding]; other site
568709012700	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
568709012701	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
568709012702	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
568709012703	transcriptional repressor IclR; Provisional; Region: PRK11569
568709012704	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
568709012705	Bacterial transcriptional regulator; Region: IclR; pfam01614
568709012706	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
568709012707	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
568709012708	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
568709012709	substrate binding pocket [chemical binding]; other site
568709012710	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
568709012711	B12 binding site [chemical binding]; other site
568709012712	cobalt ligand [ion binding]; other site
568709012713	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
568709012714	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
568709012715	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
568709012716	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
568709012717	active site pocket [active]
568709012718	oxyanion hole [active]
568709012719	catalytic triad [active]
568709012720	active site nucleophile [active]
568709012721	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
568709012722	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
568709012723	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
568709012724	RNA binding surface [nucleotide binding]; other site
568709012725	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
568709012726	probable active site [active]
568709012727	hypothetical protein; Provisional; Region: PRK10515
568709012728	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
568709012729	Sodium Bile acid symporter family; Region: SBF; pfam01758
568709012730	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
568709012731	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
568709012732	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
568709012733	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
568709012734	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
568709012735	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
568709012736	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
568709012737	Phage-related baseplate assembly protein [General function prediction only]; Region: COG3948
568709012738	Phage baseplate assembly protein W [General function prediction only]; Region: COG3628
568709012739	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
568709012740	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
568709012741	Ligand binding site; other site
568709012742	Putative Catalytic site; other site
568709012743	DXD motif; other site
568709012744	Predicted membrane protein [Function unknown]; Region: COG2246
568709012745	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
568709012746	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
568709012747	Phage protein D [General function prediction only]; Region: COG3500
568709012748	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
568709012749	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
568709012750	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
568709012751	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
568709012752	Phage tail tube protein FII [General function prediction only]; Region: COG3498
568709012753	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
568709012754	Gp37 protein; Region: Gp37; pfam09646
568709012755	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
568709012756	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
568709012757	N-acetyl-D-glucosamine binding site [chemical binding]; other site
568709012758	catalytic residue [active]
568709012759	Protein of unknown function (DUF4063); Region: DUF4063; pfam13272
568709012760	Mor transcription activator family; Region: Mor; pfam08765
568709012761	aspartate kinase III; Validated; Region: PRK09084
568709012762	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
568709012763	nucleotide binding site [chemical binding]; other site
568709012764	substrate binding site [chemical binding]; other site
568709012765	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
568709012766	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
568709012767	dimer interface [polypeptide binding]; other site
568709012768	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
568709012769	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
568709012770	active site
568709012771	dimer interface [polypeptide binding]; other site
568709012772	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
568709012773	dimer interface [polypeptide binding]; other site
568709012774	active site
568709012775	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
568709012776	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
568709012777	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
568709012778	Predicted membrane protein [Function unknown]; Region: COG3223
568709012779	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
568709012780	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709012781	dimer interface [polypeptide binding]; other site
568709012782	conserved gate region; other site
568709012783	putative PBP binding loops; other site
568709012784	ABC-ATPase subunit interface; other site
568709012785	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
568709012786	dimer interface [polypeptide binding]; other site
568709012787	conserved gate region; other site
568709012788	putative PBP binding loops; other site
568709012789	ABC-ATPase subunit interface; other site
568709012790	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
568709012791	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
568709012792	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
568709012793	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
568709012794	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
568709012795	Walker A/P-loop; other site
568709012796	ATP binding site [chemical binding]; other site
568709012797	Q-loop/lid; other site
568709012798	ABC transporter signature motif; other site
568709012799	Walker B; other site
568709012800	D-loop; other site
568709012801	H-loop/switch region; other site
568709012802	TOBE domain; Region: TOBE_2; pfam08402
568709012803	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
568709012804	trimer interface; other site
568709012805	sugar binding site [chemical binding]; other site
568709012806	maltose regulon periplasmic protein; Provisional; Region: PRK10564
568709012807	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
568709012808	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
568709012809	UbiA prenyltransferase family; Region: UbiA; pfam01040
568709012810	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
568709012811	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
568709012812	putative acyl-acceptor binding pocket; other site
568709012813	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
568709012814	LexA repressor; Validated; Region: PRK00215
568709012815	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
568709012816	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
568709012817	Catalytic site [active]
568709012818	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
568709012819	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
568709012820	hypothetical protein; Provisional; Region: PRK10428
568709012821	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
568709012822	metal binding site 2 [ion binding]; metal-binding site
568709012823	putative DNA binding helix; other site
568709012824	metal binding site 1 [ion binding]; metal-binding site
568709012825	dimer interface [polypeptide binding]; other site
568709012826	structural Zn2+ binding site [ion binding]; other site
568709012827	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
568709012828	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
568709012829	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
568709012830	FMN binding site [chemical binding]; other site
568709012831	active site
568709012832	catalytic residues [active]
568709012833	substrate binding site [chemical binding]; other site
568709012834	phage shock protein G; Reviewed; Region: pspG; PRK09459
568709012835	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
568709012836	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
568709012837	NADP binding site [chemical binding]; other site
568709012838	dimer interface [polypeptide binding]; other site
568709012839	replicative DNA helicase; Provisional; Region: PRK08006
568709012840	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
568709012841	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
568709012842	Walker A motif; other site
568709012843	ATP binding site [chemical binding]; other site
568709012844	Walker B motif; other site
568709012845	DNA binding loops [nucleotide binding]
568709012846	alanine racemase; Reviewed; Region: alr; PRK00053
568709012847	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
568709012848	active site
568709012849	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
568709012850	substrate binding site [chemical binding]; other site
568709012851	catalytic residues [active]
568709012852	dimer interface [polypeptide binding]; other site
568709012853	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
568709012854	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
568709012855	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709012856	homodimer interface [polypeptide binding]; other site
568709012857	catalytic residue [active]
568709012859	Uncharacterized conserved protein [Function unknown]; Region: COG0432
568709012860	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
568709012861	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
568709012862	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
568709012863	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
568709012864	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
568709012865	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
568709012866	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
568709012867	dimer interface [polypeptide binding]; other site
568709012868	ssDNA binding site [nucleotide binding]; other site
568709012869	tetramer (dimer of dimers) interface [polypeptide binding]; other site
568709012870	hypothetical protein; Validated; Region: PRK09039
568709012871	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
568709012872	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
568709012873	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
568709012874	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
568709012875	HlyD family secretion protein; Region: HlyD_3; pfam13437
568709012876	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
568709012877	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012878	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012879	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012880	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012881	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012882	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
568709012883	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
568709012884	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012885	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
568709012886	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
568709012887	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012888	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
568709012889	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012890	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
568709012891	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
568709012892	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012893	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
568709012894	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012895	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
568709012896	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
568709012897	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012898	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
568709012899	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
568709012900	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012901	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
568709012902	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012903	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012904	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
568709012905	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012906	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012907	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012908	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012909	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012910	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
568709012911	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012912	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
568709012913	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012914	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
568709012915	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012916	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
568709012917	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
568709012918	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709012919	Walker A/P-loop; other site
568709012920	ATP binding site [chemical binding]; other site
568709012921	Q-loop/lid; other site
568709012922	ABC transporter signature motif; other site
568709012923	Walker B; other site
568709012924	D-loop; other site
568709012925	H-loop/switch region; other site
568709012926	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
568709012927	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
568709012928	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
568709012929	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
568709012930	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709012931	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
568709012932	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
568709012933	DNA binding residues [nucleotide binding]
568709012934	dimer interface [polypeptide binding]; other site
568709012935	[2Fe-2S] cluster binding site [ion binding]; other site
568709012936	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
568709012937	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
568709012938	putative C-terminal domain interface [polypeptide binding]; other site
568709012939	putative GSH binding site (G-site) [chemical binding]; other site
568709012940	putative dimer interface [polypeptide binding]; other site
568709012941	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
568709012942	putative N-terminal domain interface [polypeptide binding]; other site
568709012943	putative dimer interface [polypeptide binding]; other site
568709012944	putative substrate binding pocket (H-site) [chemical binding]; other site
568709012945	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
568709012946	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
568709012947	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
568709012948	Transcriptional regulator [Transcription]; Region: LysR; COG0583
568709012949	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709012950	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
568709012951	putative dimerization interface [polypeptide binding]; other site
568709012952	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
568709012953	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
568709012954	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
568709012955	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
568709012956	Na binding site [ion binding]; other site
568709012957	Predicted membrane protein [Function unknown]; Region: COG3162
568709012958	acetyl-CoA synthetase; Provisional; Region: PRK00174
568709012959	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
568709012960	active site
568709012961	CoA binding site [chemical binding]; other site
568709012962	acyl-activating enzyme (AAE) consensus motif; other site
568709012963	AMP binding site [chemical binding]; other site
568709012964	acetate binding site [chemical binding]; other site
568709012965	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
568709012966	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
568709012967	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
568709012968	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
568709012969	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
568709012970	heme lyase subunit NrfE; Provisional; Region: PRK10369
568709012971	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
568709012972	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
568709012973	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
568709012974	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
568709012975	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
568709012976	Sel1-like repeats; Region: SEL1; smart00671
568709012977	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709012978	molybdopterin cofactor binding site; other site
568709012979	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
568709012980	molybdopterin cofactor binding site; other site
568709012981	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
568709012982	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
568709012983	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709012984	Coenzyme A binding pocket [chemical binding]; other site
568709012985	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
568709012986	dimer interface [polypeptide binding]; other site
568709012987	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
568709012988	hypothetical protein; Provisional; Region: PRK10220
568709012989	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
568709012990	PhnA protein; Region: PhnA; pfam03831
568709012991	proline/glycine betaine transporter; Provisional; Region: PRK10642
568709012992	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709012993	putative substrate translocation pore; other site
568709012994	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
568709012995	sensor protein BasS/PmrB; Provisional; Region: PRK10755
568709012996	HAMP domain; Region: HAMP; pfam00672
568709012997	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709012998	dimer interface [polypeptide binding]; other site
568709012999	phosphorylation site [posttranslational modification]
568709013000	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709013001	ATP binding site [chemical binding]; other site
568709013002	Mg2+ binding site [ion binding]; other site
568709013003	G-X-G motif; other site
568709013004	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
568709013005	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709013006	active site
568709013007	phosphorylation site [posttranslational modification]
568709013008	intermolecular recognition site; other site
568709013009	dimerization interface [polypeptide binding]; other site
568709013010	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709013011	DNA binding site [nucleotide binding]
568709013012	putative metal dependent hydrolase; Provisional; Region: PRK11598
568709013013	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
568709013014	Sulfatase; Region: Sulfatase; pfam00884
568709013015	arginine:agmatin antiporter; Provisional; Region: PRK10644
568709013016	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
568709013017	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709013018	arginine decarboxylase; Provisional; Region: PRK15029
568709013019	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
568709013020	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
568709013021	homodimer interface [polypeptide binding]; other site
568709013022	pyridoxal 5'-phosphate binding site [chemical binding]; other site
568709013023	catalytic residue [active]
568709013024	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
568709013025	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
568709013026	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709013027	alpha-galactosidase; Provisional; Region: PRK15076
568709013028	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
568709013029	NAD binding site [chemical binding]; other site
568709013030	sugar binding site [chemical binding]; other site
568709013031	divalent metal binding site [ion binding]; other site
568709013032	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
568709013033	dimer interface [polypeptide binding]; other site
568709013034	melibiose:sodium symporter; Provisional; Region: PRK10429
568709013035	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
568709013036	fumarate hydratase; Provisional; Region: PRK15389
568709013037	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
568709013038	Fumarase C-terminus; Region: Fumerase_C; pfam05683
568709013039	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
568709013040	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
568709013041	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
568709013042	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709013043	active site
568709013044	phosphorylation site [posttranslational modification]
568709013045	intermolecular recognition site; other site
568709013046	dimerization interface [polypeptide binding]; other site
568709013047	sensory histidine kinase DcuS; Provisional; Region: PRK11086
568709013048	PAS domain; Region: PAS; smart00091
568709013049	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709013050	ATP binding site [chemical binding]; other site
568709013051	Mg2+ binding site [ion binding]; other site
568709013052	G-X-G motif; other site
568709013053	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
568709013054	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
568709013055	putative [Fe4-S4] binding site [ion binding]; other site
568709013056	putative molybdopterin cofactor binding site [chemical binding]; other site
568709013057	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
568709013058	putative molybdopterin cofactor binding site; other site
568709013059	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
568709013060	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
568709013061	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
568709013062	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
568709013063	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
568709013064	SdiA-regulated; Region: SdiA-regulated; cd09971
568709013065	putative active site [active]
568709013066	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
568709013067	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709013068	DNA binding residues [nucleotide binding]
568709013069	dimerization interface [polypeptide binding]; other site
568709013070	AraC family transcriptional regulator; Provisional; Region: PRK15186
568709013071	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709013072	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
568709013073	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709013074	Coenzyme A binding pocket [chemical binding]; other site
568709013075	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
568709013076	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
568709013077	active site
568709013078	EthD domain; Region: EthD; pfam07110
568709013079	Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg3; cd01282
568709013080	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
568709013081	DNA binding residues [nucleotide binding]
568709013082	putative dimer interface [polypeptide binding]; other site
568709013083	putative transcriptional regulator; Provisional; Region: PRK11640
568709013084	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
568709013085	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
568709013086	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
568709013087	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
568709013088	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
568709013089	DsbD alpha interface [polypeptide binding]; other site
568709013090	catalytic residues [active]
568709013091	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
568709013092	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
568709013093	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
568709013094	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
568709013095	Aspartase; Region: Aspartase; cd01357
568709013096	active sites [active]
568709013097	tetramer interface [polypeptide binding]; other site
568709013098	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
568709013099	putative transporter; Provisional; Region: PRK11021
568709013100	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
568709013101	oligomerisation interface [polypeptide binding]; other site
568709013102	mobile loop; other site
568709013103	roof hairpin; other site
568709013104	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
568709013105	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
568709013106	ring oligomerisation interface [polypeptide binding]; other site
568709013107	ATP/Mg binding site [chemical binding]; other site
568709013108	stacking interactions; other site
568709013109	hinge regions; other site
568709013110	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
568709013111	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
568709013112	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709013113	FeS/SAM binding site; other site
568709013114	elongation factor P; Validated; Region: PRK00529
568709013115	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
568709013116	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
568709013117	RNA binding site [nucleotide binding]; other site
568709013118	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
568709013119	RNA binding site [nucleotide binding]; other site
568709013120	Predicted small secreted protein [Function unknown]; Region: COG5510
568709013121	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
568709013122	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
568709013123	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709013124	DNA binding residues [nucleotide binding]
568709013125	dimerization interface [polypeptide binding]; other site
568709013126	multidrug efflux system protein; Provisional; Region: PRK11431
568709013127	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
568709013128	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
568709013129	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
568709013130	Iron-sulfur protein interface; other site
568709013131	proximal quinone binding site [chemical binding]; other site
568709013132	C-subunit interface; other site
568709013133	distal quinone binding site; other site
568709013134	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
568709013135	D-subunit interface [polypeptide binding]; other site
568709013136	Iron-sulfur protein interface; other site
568709013137	proximal quinone binding site [chemical binding]; other site
568709013138	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
568709013139	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
568709013140	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
568709013141	L-aspartate oxidase; Provisional; Region: PRK06175
568709013142	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
568709013143	poxB regulator PoxA; Provisional; Region: PRK09350
568709013144	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
568709013145	motif 1; other site
568709013146	dimer interface [polypeptide binding]; other site
568709013147	active site
568709013148	motif 2; other site
568709013149	motif 3; other site
568709013150	inner membrane transporter YjeM; Provisional; Region: PRK15238
568709013151	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
568709013152	putative mechanosensitive channel protein; Provisional; Region: PRK10929
568709013153	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
568709013154	Mechanosensitive ion channel; Region: MS_channel; pfam00924
568709013155	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
568709013156	GTPase RsgA; Reviewed; Region: PRK12288
568709013157	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
568709013158	RNA binding site [nucleotide binding]; other site
568709013159	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
568709013160	GTPase/Zn-binding domain interface [polypeptide binding]; other site
568709013161	GTP/Mg2+ binding site [chemical binding]; other site
568709013162	G4 box; other site
568709013163	G5 box; other site
568709013164	G1 box; other site
568709013165	Switch I region; other site
568709013166	G2 box; other site
568709013167	G3 box; other site
568709013168	Switch II region; other site
568709013169	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
568709013170	catalytic site [active]
568709013171	putative active site [active]
568709013172	putative substrate binding site [chemical binding]; other site
568709013173	dimer interface [polypeptide binding]; other site
568709013174	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
568709013175	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
568709013176	substrate binding pocket [chemical binding]; other site
568709013177	membrane-bound complex binding site; other site
568709013178	hinge residues; other site
568709013179	epoxyqueuosine reductase; Region: TIGR00276
568709013180	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
568709013181	putative carbohydrate kinase; Provisional; Region: PRK10565
568709013182	Uncharacterized conserved protein [Function unknown]; Region: COG0062
568709013183	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
568709013184	putative substrate binding site [chemical binding]; other site
568709013185	putative ATP binding site [chemical binding]; other site
568709013186	ADP-binding protein; Provisional; Region: PRK10646
568709013187	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
568709013188	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
568709013189	active site
568709013190	metal binding site [ion binding]; metal-binding site
568709013191	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
568709013192	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709013193	ATP binding site [chemical binding]; other site
568709013194	Mg2+ binding site [ion binding]; other site
568709013195	G-X-G motif; other site
568709013196	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
568709013197	ATP binding site [chemical binding]; other site
568709013198	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
568709013199	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
568709013200	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
568709013201	bacterial Hfq-like; Region: Hfq; cd01716
568709013202	hexamer interface [polypeptide binding]; other site
568709013203	Sm1 motif; other site
568709013204	RNA binding site [nucleotide binding]; other site
568709013205	Sm2 motif; other site
568709013206	GTPase HflX; Provisional; Region: PRK11058
568709013207	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
568709013208	HflX GTPase family; Region: HflX; cd01878
568709013209	G1 box; other site
568709013210	GTP/Mg2+ binding site [chemical binding]; other site
568709013211	Switch I region; other site
568709013212	G2 box; other site
568709013213	G3 box; other site
568709013214	Switch II region; other site
568709013215	G4 box; other site
568709013216	G5 box; other site
568709013217	FtsH protease regulator HflK; Provisional; Region: PRK10930
568709013218	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
568709013219	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
568709013220	FtsH protease regulator HflC; Provisional; Region: PRK11029
568709013221	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
568709013222	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
568709013223	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
568709013224	GDP-binding site [chemical binding]; other site
568709013225	ACT binding site; other site
568709013226	IMP binding site; other site
568709013227	Predicted transcriptional regulator [Transcription]; Region: COG1959
568709013228	transcriptional repressor NsrR; Provisional; Region: PRK11014
568709013229	exoribonuclease R; Provisional; Region: PRK11642
568709013230	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
568709013231	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
568709013232	RNB domain; Region: RNB; pfam00773
568709013233	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
568709013234	RNA binding site [nucleotide binding]; other site
568709013235	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
568709013236	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
568709013237	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
568709013238	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3789
568709013239	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
568709013240	Ion channel; Region: Ion_trans_2; pfam07885
568709013241	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
568709013242	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
568709013243	Predicted membrane protein [Function unknown]; Region: COG3766
568709013244	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
568709013245	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
568709013246	Predicted integral membrane protein [Function unknown]; Region: COG5463
568709013247	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
568709013248	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
568709013249	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
568709013250	FAD binding site [chemical binding]; other site
568709013251	substrate binding site [chemical binding]; other site
568709013252	catalytic residues [active]
568709013253	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
568709013254	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
568709013255	esterase; Provisional; Region: PRK10566
568709013256	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
568709013257	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
568709013258	transcriptional repressor UlaR; Provisional; Region: PRK13509
568709013259	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
568709013260	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
568709013261	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
568709013262	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
568709013263	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
568709013264	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
568709013265	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
568709013266	active site
568709013267	P-loop; other site
568709013268	phosphorylation site [posttranslational modification]
568709013269	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709013270	active site
568709013271	phosphorylation site [posttranslational modification]
568709013272	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
568709013273	active site
568709013274	dimer interface [polypeptide binding]; other site
568709013275	magnesium binding site [ion binding]; other site
568709013276	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
568709013277	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
568709013278	AP (apurinic/apyrimidinic) site pocket; other site
568709013279	DNA interaction; other site
568709013280	Metal-binding active site; metal-binding site
568709013281	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
568709013282	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
568709013283	intersubunit interface [polypeptide binding]; other site
568709013284	active site
568709013285	Zn2+ binding site [ion binding]; other site
568709013286	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
568709013287	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
568709013288	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
568709013289	dimer interface [polypeptide binding]; other site
568709013290	ssDNA binding site [nucleotide binding]; other site
568709013291	tetramer (dimer of dimers) interface [polypeptide binding]; other site
568709013292	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
568709013293	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
568709013294	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
568709013295	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
568709013296	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
568709013297	EamA-like transporter family; Region: EamA; pfam00892
568709013298	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
568709013299	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
568709013300	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
568709013301	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
568709013302	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
568709013303	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
568709013304	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
568709013305	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
568709013306	Hemerythrin-like domain; Region: Hr-like; cd12108
568709013307	Fe binding site [ion binding]; other site
568709013308	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
568709013309	EamA-like transporter family; Region: EamA; pfam00892
568709013310	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
568709013311	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
568709013312	NADP binding site [chemical binding]; other site
568709013313	Predicted transcriptional regulators [Transcription]; Region: COG1733
568709013314	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
568709013315	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
568709013316	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
568709013317	active site
568709013318	metal binding site [ion binding]; metal-binding site
568709013319	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
568709013320	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
568709013321	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
568709013322	active site
568709013323	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
568709013324	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
568709013325	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
568709013326	Domain of unknown function DUF21; Region: DUF21; pfam01595
568709013327	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
568709013328	Transporter associated domain; Region: CorC_HlyC; smart01091
568709013329	methionine sulfoxide reductase A; Provisional; Region: PRK00058
568709013330	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
568709013331	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
568709013332	Surface antigen; Region: Bac_surface_Ag; pfam01103
568709013333	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
568709013334	Family of unknown function (DUF490); Region: DUF490; pfam04357
568709013335	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
568709013336	putative active site pocket [active]
568709013337	dimerization interface [polypeptide binding]; other site
568709013338	putative catalytic residue [active]
568709013339	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709013340	D-galactonate transporter; Region: 2A0114; TIGR00893
568709013341	putative substrate translocation pore; other site
568709013342	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
568709013343	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
568709013344	active site
568709013345	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
568709013346	dimer interface [polypeptide binding]; other site
568709013347	substrate binding site [chemical binding]; other site
568709013348	metal binding sites [ion binding]; metal-binding site
568709013349	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
568709013350	AMP binding site [chemical binding]; other site
568709013351	metal binding site [ion binding]; metal-binding site
568709013352	active site
568709013353	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
568709013354	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
568709013355	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
568709013356	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
568709013357	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
568709013358	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
568709013359	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
568709013360	putative active site [active]
568709013361	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
568709013362	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709013363	putative substrate translocation pore; other site
568709013364	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709013365	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
568709013366	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709013367	putative substrate translocation pore; other site
568709013368	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709013369	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
568709013370	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
568709013371	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
568709013372	tetrameric interface [polypeptide binding]; other site
568709013373	NAD binding site [chemical binding]; other site
568709013374	catalytic residues [active]
568709013375	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
568709013376	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
568709013377	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709013378	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
568709013379	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568709013380	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568709013381	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
568709013382	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
568709013383	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
568709013384	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
568709013385	major facilitator superfamily transporter; Provisional; Region: PRK05122
568709013386	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709013387	putative substrate translocation pore; other site
568709013388	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
568709013389	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
568709013390	substrate binding site [chemical binding]; other site
568709013391	ATP binding site [chemical binding]; other site
568709013392	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
568709013393	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
568709013394	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
568709013395	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
568709013396	PYR/PP interface [polypeptide binding]; other site
568709013397	dimer interface [polypeptide binding]; other site
568709013398	TPP binding site [chemical binding]; other site
568709013399	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
568709013400	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
568709013401	TPP-binding site; other site
568709013402	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
568709013403	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
568709013404	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
568709013405	polyol permease family; Region: 2A0118; TIGR00897
568709013406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709013407	putative substrate translocation pore; other site
568709013408	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
568709013409	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
568709013410	DNA interaction; other site
568709013411	Metal-binding active site; metal-binding site
568709013412	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
568709013413	hypothetical protein; Provisional; Region: PRK05255
568709013414	peptidase PmbA; Provisional; Region: PRK11040
568709013415	cytochrome b562; Provisional; Region: PRK15058
568709013416	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
568709013417	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
568709013418	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
568709013419	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
568709013420	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
568709013421	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
568709013422	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
568709013423	active site
568709013424	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
568709013425	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
568709013426	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
568709013427	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
568709013428	HTH domain; Region: HTH_11; pfam08279
568709013429	Mga helix-turn-helix domain; Region: Mga; pfam05043
568709013430	PRD domain; Region: PRD; pfam00874
568709013431	PRD domain; Region: PRD; pfam00874
568709013432	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
568709013433	active site
568709013434	P-loop; other site
568709013435	phosphorylation site [posttranslational modification]
568709013436	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
568709013437	active site
568709013438	phosphorylation site [posttranslational modification]
568709013439	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
568709013440	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
568709013441	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
568709013442	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709013443	FeS/SAM binding site; other site
568709013444	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
568709013445	ATP cone domain; Region: ATP-cone; pfam03477
568709013446	Class III ribonucleotide reductase; Region: RNR_III; cd01675
568709013447	effector binding site; other site
568709013448	active site
568709013449	Zn binding site [ion binding]; other site
568709013450	glycine loop; other site
568709013451	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
568709013452	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
568709013453	Ca binding site [ion binding]; other site
568709013454	active site
568709013455	catalytic site [active]
568709013456	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
568709013457	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
568709013458	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
568709013459	active site turn [active]
568709013460	phosphorylation site [posttranslational modification]
568709013461	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
568709013462	trehalose repressor; Provisional; Region: treR; PRK09492
568709013463	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709013464	DNA binding site [nucleotide binding]
568709013465	domain linker motif; other site
568709013466	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
568709013467	dimerization interface [polypeptide binding]; other site
568709013468	ligand binding site [chemical binding]; other site
568709013470	Transposase; Region: HTH_Tnp_1; cl17663
568709013471	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
568709013472	homotrimer interaction site [polypeptide binding]; other site
568709013473	putative active site [active]
568709013474	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
568709013475	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
568709013476	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
568709013477	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
568709013478	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
568709013479	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
568709013480	pyrBI operon leader peptide; Provisional; Region: PRK10224
568709013481	Arginine repressor [Transcription]; Region: ArgR; COG1438
568709013482	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
568709013483	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
568709013484	Predicted membrane protein [Function unknown]; Region: COG1288
568709013485	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
568709013486	ornithine carbamoyltransferase; Validated; Region: PRK02102
568709013487	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
568709013488	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
568709013489	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
568709013490	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
568709013491	putative substrate binding site [chemical binding]; other site
568709013492	nucleotide binding site [chemical binding]; other site
568709013493	nucleotide binding site [chemical binding]; other site
568709013494	homodimer interface [polypeptide binding]; other site
568709013495	arginine deiminase; Provisional; Region: PRK01388
568709013496	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
568709013497	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
568709013498	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
568709013499	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
568709013500	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
568709013501	RNase E inhibitor protein; Provisional; Region: PRK11191
568709013502	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
568709013503	active site
568709013504	dinuclear metal binding site [ion binding]; other site
568709013505	dimerization interface [polypeptide binding]; other site
568709013506	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
568709013507	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
568709013508	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709013509	Coenzyme A binding pocket [chemical binding]; other site
568709013510	Predicted membrane protein [Function unknown]; Region: COG4269
568709013511	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
568709013512	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
568709013513	HIGH motif; other site
568709013514	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
568709013515	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
568709013516	active site
568709013517	KMSKS motif; other site
568709013518	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
568709013519	tRNA binding surface [nucleotide binding]; other site
568709013520	anticodon binding site; other site
568709013521	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
568709013522	DNA polymerase III subunit chi; Validated; Region: PRK05728
568709013523	multifunctional aminopeptidase A; Provisional; Region: PRK00913
568709013524	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
568709013525	interface (dimer of trimers) [polypeptide binding]; other site
568709013526	Substrate-binding/catalytic site; other site
568709013527	Zn-binding sites [ion binding]; other site
568709013528	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
568709013529	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
568709013530	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
568709013531	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
568709013532	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
568709013533	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
568709013534	DNA binding site [nucleotide binding]
568709013535	domain linker motif; other site
568709013536	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
568709013537	putative dimerization interface [polypeptide binding]; other site
568709013538	putative ligand binding site [chemical binding]; other site
568709013539	gluconate transporter; Region: gntP; TIGR00791
568709013540	fructuronate transporter; Provisional; Region: PRK10034; cl15264
568709013541	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
568709013542	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
568709013543	NADP binding site [chemical binding]; other site
568709013544	homodimer interface [polypeptide binding]; other site
568709013545	active site
568709013546	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
568709013547	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
568709013548	putative NAD(P) binding site [chemical binding]; other site
568709013549	catalytic Zn binding site [ion binding]; other site
568709013550	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
568709013551	ATP-binding site [chemical binding]; other site
568709013552	Gluconate-6-phosphate binding site [chemical binding]; other site
568709013553	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
568709013554	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
568709013555	putative NAD(P) binding site [chemical binding]; other site
568709013556	putative substrate binding site [chemical binding]; other site
568709013557	catalytic Zn binding site [ion binding]; other site
568709013558	structural Zn binding site [ion binding]; other site
568709013559	dimer interface [polypeptide binding]; other site
568709013560	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
568709013561	Part of AAA domain; Region: AAA_19; pfam13245
568709013562	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
568709013563	AAA domain; Region: AAA_12; pfam13087
568709013564	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
568709013565	putative active site [active]
568709013566	catalytic site [active]
568709013567	Uncharacterized conserved protein [Function unknown]; Region: COG4127
568709013568	Restriction endonuclease; Region: Mrr_cat; pfam04471
568709013569	conserved hypothetical protein; Region: Lon_rel_chp; TIGR02653
568709013570	Putative ATP-dependent Lon protease; Region: Lon_2; pfam13337
568709013571	TIGR02687 family protein; Region: TIGR02687
568709013572	PglZ domain; Region: PglZ; pfam08665
568709013573	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709013574	AAA domain; Region: AAA_21; pfam13304
568709013575	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
568709013576	Walker A/P-loop; other site
568709013577	Walker A/P-loop; other site
568709013578	ATP binding site [chemical binding]; other site
568709013579	ATP binding site [chemical binding]; other site
568709013580	Q-loop/lid; other site
568709013581	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
568709013582	Methyltransferase domain; Region: Methyltransf_26; pfam13659
568709013583	TIGR02680 family protein; Region: TIGR02680
568709013584	Domain of unknown function (DUF1788); Region: DUF1788; pfam08747
568709013585	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
568709013587	hypothetical protein; Provisional; Region: PRK12378
568709013588	Methyltransferase domain; Region: Methyltransf_23; pfam13489
568709013589	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709013590	S-adenosylmethionine binding site [chemical binding]; other site
568709013591	Methyltransferase domain; Region: Methyltransf_31; pfam13847
568709013592	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709013593	S-adenosylmethionine binding site [chemical binding]; other site
568709013594	hypothetical protein; Provisional; Region: PRK13687
568709013595	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4332
568709013596	Uncharacterized conserved protein [Function unknown]; Region: COG3439
568709013597	Dienelactone hydrolase family; Region: DLH; pfam01738
568709013598	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
568709013599	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
568709013600	DNA-binding site [nucleotide binding]; DNA binding site
568709013601	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
568709013602	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
568709013603	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
568709013604	active site
568709013605	HIGH motif; other site
568709013606	dimer interface [polypeptide binding]; other site
568709013607	KMSKS motif; other site
568709013608	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
568709013609	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
568709013610	aspartate racemase; Region: asp_race; TIGR00035
568709013611	cell density-dependent motility repressor; Provisional; Region: PRK10082
568709013612	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
568709013613	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
568709013614	dimerization interface [polypeptide binding]; other site
568709013615	isoaspartyl dipeptidase; Provisional; Region: PRK10657
568709013616	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
568709013617	active site
568709013618	hypothetical protein; Provisional; Region: PRK10519
568709013619	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
568709013620	Nucleoside recognition; Region: Gate; pfam07670
568709013621	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
568709013622	Predicted membrane protein [Function unknown]; Region: COG2733
568709013623	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
568709013624	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
568709013625	putative substrate translocation pore; other site
568709013626	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
568709013627	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
568709013628	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
568709013629	NAD(P) binding site [chemical binding]; other site
568709013630	catalytic residues [active]
568709013631	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
568709013632	endoribonuclease SymE; Provisional; Region: PRK13605
568709013633	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
568709013634	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
568709013635	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
568709013636	HsdM N-terminal domain; Region: HsdM_N; pfam12161
568709013637	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
568709013638	Methyltransferase domain; Region: Methyltransf_26; pfam13659
568709013639	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
568709013640	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
568709013641	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
568709013642	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
568709013643	ATP binding site [chemical binding]; other site
568709013644	putative Mg++ binding site [ion binding]; other site
568709013645	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
568709013646	Mrr N-terminal domain; Region: Mrr_N; pfam14338
568709013647	Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; Region: CH; cl00030
568709013648	Restriction endonuclease; Region: Mrr_cat; pfam04471
568709013649	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
568709013650	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
568709013651	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
568709013652	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
568709013653	P-loop, Walker A motif; other site
568709013654	Base recognition motif; other site
568709013655	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
568709013656	Uncharacterized small protein [Function unknown]; Region: COG2879
568709013657	carbon starvation protein A; Provisional; Region: PRK15015
568709013658	Carbon starvation protein CstA; Region: CstA; pfam02554
568709013659	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
568709013660	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
568709013661	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
568709013662	dimer interface [polypeptide binding]; other site
568709013663	ligand binding site [chemical binding]; other site
568709013664	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
568709013665	dimerization interface [polypeptide binding]; other site
568709013666	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
568709013667	dimer interface [polypeptide binding]; other site
568709013668	putative CheW interface [polypeptide binding]; other site
568709013669	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
568709013670	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709013671	Walker A motif; other site
568709013672	ATP binding site [chemical binding]; other site
568709013673	Walker B motif; other site
568709013674	arginine finger; other site
568709013675	Transcriptional antiterminator [Transcription]; Region: COG3933
568709013676	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
568709013677	active pocket/dimerization site; other site
568709013678	active site
568709013679	phosphorylation site [posttranslational modification]
568709013680	PRD domain; Region: PRD; pfam00874
568709013681	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
568709013682	active pocket/dimerization site; other site
568709013683	active site
568709013684	phosphorylation site [posttranslational modification]
568709013685	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
568709013686	active site
568709013687	phosphorylation site [posttranslational modification]
568709013688	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
568709013689	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
568709013690	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
568709013691	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
568709013692	dimer interface [polypeptide binding]; other site
568709013693	active site
568709013694	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
568709013695	dimer interface [polypeptide binding]; other site
568709013696	active site
568709013697	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
568709013698	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
568709013699	putative active site [active]
568709013700	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
568709013701	phosphoglycerol transferase I; Provisional; Region: PRK03776
568709013702	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
568709013703	hypothetical protein; Provisional; Region: PRK11667
568709013704	DNA replication protein DnaC; Validated; Region: PRK07952
568709013705	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
568709013706	Walker A motif; other site
568709013707	ATP binding site [chemical binding]; other site
568709013708	Walker B motif; other site
568709013709	primosomal protein DnaI; Provisional; Region: PRK02854
568709013710	hypothetical protein; Provisional; Region: PRK09917
568709013711	Uncharacterized conserved protein [Function unknown]; Region: COG2966
568709013712	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
568709013713	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
568709013714	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709013715	DNA binding residues [nucleotide binding]
568709013716	dimerization interface [polypeptide binding]; other site
568709013717	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
568709013718	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
568709013719	DNA binding residues [nucleotide binding]
568709013720	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
568709013721	putative deacylase active site [active]
568709013722	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
568709013723	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
568709013724	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
568709013725	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
568709013726	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
568709013727	metal binding site [ion binding]; metal-binding site
568709013728	active site
568709013729	I-site; other site
568709013730	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
568709013731	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
568709013732	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
568709013733	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
568709013734	S-adenosylmethionine binding site [chemical binding]; other site
568709013735	DNA polymerase III subunit psi; Validated; Region: PRK06856
568709013736	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
568709013737	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
568709013738	Coenzyme A binding pocket [chemical binding]; other site
568709013739	dUMP phosphatase; Provisional; Region: PRK09449
568709013740	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709013741	motif II; other site
568709013742	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
568709013743	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
568709013744	G1 box; other site
568709013745	putative GEF interaction site [polypeptide binding]; other site
568709013746	GTP/Mg2+ binding site [chemical binding]; other site
568709013747	Switch I region; other site
568709013748	G2 box; other site
568709013749	G3 box; other site
568709013750	Switch II region; other site
568709013751	G4 box; other site
568709013752	G5 box; other site
568709013753	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
568709013754	periplasmic protein; Provisional; Region: PRK10568
568709013755	BON domain; Region: BON; pfam04972
568709013756	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
568709013757	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
568709013758	active site
568709013759	nucleophile elbow; other site
568709013760	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
568709013761	active site
568709013762	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
568709013763	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
568709013764	FeS/SAM binding site; other site
568709013765	hypothetical protein; Provisional; Region: PRK10977
568709013766	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
568709013767	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
568709013768	intersubunit interface [polypeptide binding]; other site
568709013769	active site
568709013770	catalytic residue [active]
568709013771	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
568709013772	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
568709013773	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
568709013774	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
568709013775	phosphopentomutase; Provisional; Region: PRK05362
568709013776	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
568709013777	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
568709013778	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
568709013779	hypothetical protein; Provisional; Region: PRK15301
568709013780	putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304
568709013781	PapC N-terminal domain; Region: PapC_N; pfam13954
568709013782	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709013783	PapC C-terminal domain; Region: PapC_C; pfam13953
568709013784	putative fimbrial chaperone protein; Provisional; Region: PRK09918
568709013785	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709013786	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709013787	hypothetical protein; Provisional; Region: PRK15302
568709013788	hypothetical protein; Provisional; Region: PRK15303
568709013789	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
568709013790	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
568709013791	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
568709013792	hypothetical protein; Provisional; Region: PRK11246
568709013793	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
568709013794	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
568709013795	motif II; other site
568709013796	DNA repair protein RadA; Region: sms; TIGR00416
568709013797	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
568709013798	Walker A motif/ATP binding site; other site
568709013799	ATP binding site [chemical binding]; other site
568709013800	Walker B motif; other site
568709013801	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
568709013802	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
568709013803	non-specific DNA binding site [nucleotide binding]; other site
568709013804	salt bridge; other site
568709013805	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
568709013806	sequence-specific DNA binding site [nucleotide binding]; other site
568709013807	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
568709013808	active site
568709013809	(T/H)XGH motif; other site
568709013810	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
568709013811	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
568709013812	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568709013813	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568709013814	ABC transporter; Region: ABC_tran_2; pfam12848
568709013815	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
568709013816	lytic murein transglycosylase; Provisional; Region: PRK11619
568709013817	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
568709013818	N-acetyl-D-glucosamine binding site [chemical binding]; other site
568709013819	catalytic residue [active]
568709013820	Trp operon repressor; Provisional; Region: PRK01381
568709013821	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
568709013822	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
568709013823	catalytic core [active]
568709013824	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
568709013825	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
568709013826	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
568709013827	hypothetical protein; Provisional; Region: PRK10756
568709013828	CreA protein; Region: CreA; pfam05981
568709013829	DNA-binding response regulator CreB; Provisional; Region: PRK11083
568709013830	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709013831	active site
568709013832	phosphorylation site [posttranslational modification]
568709013833	intermolecular recognition site; other site
568709013834	dimerization interface [polypeptide binding]; other site
568709013835	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709013836	DNA binding site [nucleotide binding]
568709013837	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
568709013838	dimerization interface [polypeptide binding]; other site
568709013839	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
568709013840	dimer interface [polypeptide binding]; other site
568709013841	phosphorylation site [posttranslational modification]
568709013842	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
568709013843	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
568709013844	ATP binding site [chemical binding]; other site
568709013845	Mg2+ binding site [ion binding]; other site
568709013846	G-X-G motif; other site
568709013847	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
568709013848	putative major fimbrial protein SthE; Provisional; Region: PRK15292
568709013849	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
568709013850	putative fimbrial protein SthD; Provisional; Region: PRK15293
568709013851	putative fimbrial outer membrane usher protein SthC; Provisional; Region: PRK15294
568709013852	PapC N-terminal domain; Region: PapC_N; pfam13954
568709013853	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
568709013854	PapC C-terminal domain; Region: PapC_C; pfam13953
568709013855	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
568709013856	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
568709013857	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
568709013858	putative fimbrial protein SthA; Provisional; Region: PRK15296
568709013859	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
568709013860	Helix-turn-helix domain; Region: HTH_36; pfam13730
568709013861	two-component response regulator; Provisional; Region: PRK11173
568709013862	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
568709013863	active site
568709013864	phosphorylation site [posttranslational modification]
568709013865	intermolecular recognition site; other site
568709013866	dimerization interface [polypeptide binding]; other site
568709013867	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
568709013868	DNA binding site [nucleotide binding]
568709013869	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
568709013870	putative RNA methyltransferase; Provisional; Region: PRK10433