-- dump date   	20140620_055251
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
NP_459007.1	multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways
NP_459008.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
NP_459009.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
NP_459012.1	Maintains the balance of metabolites in the pentose-phosphate pathway
NP_459013.1	forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis
NP_459017.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
NP_459018.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
NP_459028.1	bovine colonization factor BcfC
NP_459044.1	exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH
NP_459045.1	Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC
NP_459048.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
NP_459050.1	catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
NP_459051.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
NP_459052.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
NP_459054.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
NP_459056.1	catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides
NP_459059.1	oxaloacetate decarboxylase beta chain (SW:DCOB_SALTY)
NP_459060.1	catalyzes the formation of pyruvate from oxaloacetate
NP_459061.1	catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide
NP_459064.1	acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate
NP_459066.1	citrate-ACP transferase
NP_459068.1	modifier of citrate lyase protein
NP_459069.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
NP_459071.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
NP_459072.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
NP_459073.1	regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons
NP_459074.1	involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities
NP_459075.1	catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA
NP_459077.1	catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine
NP_459078.1	catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA
NP_459079.1	catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism
NP_459080.1	required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase
NP_459081.1	involved in electron transfer during carnitine metabolism
NP_459082.1	FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction
NP_459090.1	Required for full activity of KefC, a potassium-proton antiporter
NP_459091.1	transport system that facilitates potassium-efflux
NP_459092.1	catalyzes the reduction of dihydrofolate to tetrahydrofolate
NP_459093.1	hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP
NP_459094.1	protein associated with Co2+ and Mg2+ efflux
NP_459095.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
NP_459096.1	catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate)
NP_459097.1	peptidyl-prolyl cis-trans isomerase involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB
NP_459098.1	organic solvent tolerance protein; determines N-hexane tolerance and is involved in outer membrane permeability
NP_459099.1	functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system
NP_459100.1	catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs
NP_459101.1	ATP-dependent helicase HepA; transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA
NP_459102.1	Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C
NP_459106.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NP_459107.1	catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism
NP_459108.1	catalyzes the phosphorylation of ribulose to ribulose 5-phosphate
NP_459109.1	positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose
NP_459110.1	DedA family
NP_459111.1	with TbpA and ThiP is part of the thiamine and TPP transport system
NP_459112.1	permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine
NP_459113.1	part of the thiamine and TPP transport system tbpA-thiPQ
NP_459114.1	activates sgrS under glucose-phosphate stress conditions
NP_459115.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
NP_459116.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
NP_459117.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
NP_459118.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
NP_459119.1	involved in attenuation control of the leuABCD operon in leucine biosynthesis
NP_459120.1	activator for leuABCD operon; member of LysR family of transcriptional activators
NP_459121.1	catalytic subunit; catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive
NP_459122.1	regulatory subunit; with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors
NP_459123.1	binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism
NP_459124.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
NP_459126.1	membrane bound cell division protein at septum containing leucine zipper motif
NP_459127.1	penicillin-binding protein 3
NP_459128.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
NP_459130.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NP_459131.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
NP_459132.1	cell division protein FtsW; integral membrane protein involved in stabilizing FstZ ring during cell division
NP_459133.1	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
NP_459134.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
NP_459135.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
NP_459136.1	involved in septum formation
NP_459137.1	ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane
NP_459138.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
NP_459139.1	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis
NP_459140.2	secM translational pause allows for the initiation of secA translation
NP_459141.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
NP_459142.1	prefers dGTP; causes AT-GC transversions
NP_459145.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
NP_459146.1	guanosine 5'-monophosphate oxidoreductase; catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate
NP_459147.1	involved in biogenesis of fimbriae, protein transport, DNA uptake
NP_459150.1	quinolinate phosphoribosyltransferase; catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide
NP_459152.1	involved in regulation of beta-lactamase; signaling protein
NP_459156.1	activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex
NP_459157.1	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC
NP_459158.1	E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains
NP_459159.1	E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
NP_459163.1	catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate
NP_459166.1	transports degraded pectin products into the bacterial cell
NP_459168.1	catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate)
NP_459170.1	S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine
NP_459171.1	catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine
NP_459173.1	laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification
NP_459175.1	Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively
NP_459176.1	catalyzes the interconversion of bicarbonate and carbon dioxide
NP_459178.1	ABC superfamily membrane protein
NP_459185.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
NP_459186.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
NP_459187.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
NP_459188.1	catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP
NP_459189.1	Polymerase that creates the 3' poly(A) tail found in some mRNA's
NP_459190.2	this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu
NP_459191.1	dnaK suppressor protein (SW:DKSA_SALTY); suppresses dnaK deletion
NP_459192.1	Regulatory factor involved in maltose metabolism
NP_459195.1	penicillin-binding protein 1b; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell
NP_459196.1	involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein
NP_459197.1	part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter
NP_459198.1	Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores
NP_459199.1	part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome
NP_459200.1	major fimbrial subunit StfA
NP_459201.1	outer membrane usher protein StfC
NP_459202.1	periplasmic fimbrial chaperone StfD
NP_459203.1	minor fimbrial subunit StfE
NP_459204.1	minor fimbrial subunit StfF
NP_459205.1	minor fimbrial subunit StfG; adhesin
NP_459207.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
NP_459208.1	Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation
NP_459209.2	essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors
NP_459211.1	solute binding component of the vitamin B12 transport system BtuCDF
NP_459212.1	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
NP_459213.1	forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate
NP_459214.1	protease Do; required at high temperature; degrades damaged proteins
NP_459215.1	regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization
NP_459218.1	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway
NP_459219.1	catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein
NP_459220.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
NP_459221.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
NP_459222.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
NP_459223.1	Catalyzes the phosphorylation of UMP to UDP
NP_459224.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
NP_459225.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
NP_459226.1	catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate
NP_459227.1	catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate
NP_459228.1	catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response
NP_459229.1	part of a complex with BamABCDE; involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins
NP_459230.1	outer membrane protein OmpH
NP_459231.1	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis
NP_459232.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
NP_459233.1	UDP-N-acetylglucosamine acyltransferase; catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis
NP_459234.1	catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM
NP_459235.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
NP_459236.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase
NP_459237.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
NP_459241.1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase
NP_459242.1	Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination
NP_459244.1	hypothetical 20.8 kDa protein in mesJ-cutF intergenic region (SW:YAEQ_SALTY)
NP_459245.1	putative-tRNA hydrolase domain
NP_459246.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
NP_459250.1	part of the MetNIQ methionine uptake system
NP_459251.1	part of the metNIQ transport system for methionine
NP_459252.1	Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate
NP_459253.1	catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid
NP_459258.1	catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall
NP_459259.1	catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione
NP_459261.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
NP_459262.1	3'-5' exonuclease of DNA polymerase III
NP_459302.1	SinR protein (SW:SINR_SALTY)
NP_459307.1	functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA
NP_459308.1	catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate
NP_459311.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
NP_459314.1	catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively
NP_459315.1	fermentation/respiration switch protein; forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation
NP_459316.1	involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS
NP_459318.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
NP_459319.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
NP_459324.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
NP_459333.1	export and assembly of type 1 fimbriae
NP_459338.1	diguanylate cyclase/phosphodiesterase domain 1
NP_459352.1	type III restriction-modification system; methyltransferase (SW:T3MO_SALTY); restriction system
NP_459353.2	type III restriction-modification system enzyme (SW:T3RE_SALTY); DNA helicase
NP_459358.1	XylS/AraC transcriptional activator; AraC family
NP_459362.1	propionate catabolism operon regulatory protein (SW:PRPR_SALTY); EBP family
NP_459363.1	catalyzes the formation of pyruvate and succinate from 2-methylisocitrate
NP_459364.1	catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity
NP_459365.1	functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C
NP_459366.1	catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent
NP_459367.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
NP_459371.1	in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope
NP_459375.1	D-alanyl-alanine synthetase A; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
NP_459378.2	aids the stabilization of the sigma factor RpoS
NP_459380.1	catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis
NP_459381.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
NP_459387.1	Required for efficient pilin antigenic variation
NP_459388.1	catalyzes phosphorylation of fructose; cytosolic enzyme
NP_459389.1	member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers
NP_459390.1	with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity
NP_459391.1	with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity
NP_459392.1	two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB
NP_459393.1	membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB
NP_459394.1	branched-chain amino acid transport system II carrier protein (SW:BRNQ_SALTY); LIVCS family; LIV-II
NP_459395.1	cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation
NP_459398.1	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
NP_459399.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
NP_459400.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
NP_459401.1	member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex
NP_459402.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
NP_459403.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
NP_459406.1	hypothetical 12.6 kDa protein in secF-tsx intergenic region (SW:YAJD_SALTY)
NP_459408.1	nucleoside-specific channel-forming protein TSX (SW:TSX_SALTY); receptor of phage T6 and colicin K
NP_459411.1	riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil
NP_459412.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
NP_459413.1	Regulates rRNA biosynthesis by transcriptional antitermination
NP_459414.1	catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP
NP_459415.1	hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate
NP_459417.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
NP_459419.1	catalyzes the bidirectional exonucleolytic cleavage of DNA
NP_459420.1	Thiamine biosynthesis protein ThiI; Required for the synthesis of the thiazole moiety
NP_459421.1	probable membrane component of 2-aminoethylphosphonate transporter PhnV
NP_459422.1	probable membrane component of 2-aminoethylphosphonate transporter PhnU
NP_459423.1	probable ATPase component of 2-aminoethylphosphonate transporter PhnT
NP_459424.1	probable periplasmic binding-protein of the2-aminoethylphosphonate transporter phnS
NP_459425.1	probable repressor protein of GntR family PhnR
NP_459426.1	catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate
NP_459427.1	catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate
NP_459429.1	ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis
NP_459430.2	the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription
NP_459434.1	TPR repeat
NP_459435.1	converts protoheme IX and farnesyl diphosphate to heme O
NP_459440.1	in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein
NP_459442.1	positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress
NP_459443.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
NP_459444.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
NP_459445.1	binds and unfolds substrates as part of the ClpXP protease
NP_459447.1	histone-like DNA-binding protein
NP_459451.1	YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His
NP_459458.1	indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.
NP_459463.1	diguanylate cyclase/phosphodiesterase domain 2
NP_459464.1	RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
NP_459468.1	with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins
NP_459472.1	regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine
NP_459473.1	small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS
NP_459476.1	PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks
NP_459478.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
NP_459479.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
NP_459481.1	involved in a recombinational process of DNA repair, independent of the recBC complex
NP_459482.2	heat shock protein 90
NP_459483.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
NP_459484.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
NP_459487.1	YbaL; member of the CPA-2 family of antiporters; uncharacterized protein
NP_459489.1	cryptic in Salmonella enterica str. LT2 due to the change from a serine to a tyrosine at position 139 which eliminates the 5' nucleosidase activity PMID:11429468
NP_459494.1	activator of copper-responsive regulon genes
NP_459495.1	implicated in regulation of membrane protease activity
NP_459505.1	Maybe involved in iron-transport and virulence in Salmonella enteriditis, PMID:10447888; expression of sfbABC is increased in epithelial cells during infection in Salmonella typhimurium SL1344, PMID:18031307
NP_459506.1	May be involved in virulence, expression of sfbABC is increased in epithelial cells during infection in Salmonella typhimurium SL1344, PMID:18031307
NP_459507.1	May be involved in virulence; expression of sfbABC is increased in epithelial cells during infection in Salmonella typhimurium SL1344, PMID:18031307
NP_459508.1	catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NP_459509.1	activator of the allDC-ylbA operon involved in allantoin utilization
NP_459510.1	catalyzes the formation of glyoxylate from (S)-ureidoglycolate
NP_459511.1	regulates operons involved in the utilization of allantoin
NP_459512.1	catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate
NP_459518.1	Plays a crucial role on both purine and pyrimidine metabolism
NP_459522.1	allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide
NP_459524.1	multicopy suppressor of dominant negative ftsH mutations
NP_459527.1	forms a homodimer; may be used to synthesize carbomyl phosphate from ATP and carbamate
NP_459528.1	catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide
NP_459529.1	catalyzes the interconversion of N5-carboxyaminoimidazole ribonucleotide and 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate
NP_459530.1	catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine
NP_459532.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
NP_459537.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
NP_459538.3	type-1 fimbrial protein; A chain precursor; type-1A pilin (SW:FM1A_SALTY); major type 1 subunit
NP_459541.1	outer membrane usher protein FimD (SW:FIMD_SALTY)
NP_459542.1	in Salmonella typhimurium str. LB5010 FimH is necessary for fimbrial adhesion and involved in the uptake of Salmonella by host cells PMID:9537754, PMID:17379714; In Salmonella typhimurium str.SL1344 this protein is involved in fimbriae assembly PMID:22778099
NP_459543.1	fimbrial-like protein FimF (SW:FIMF_SALTY)
NP_459544.1	activates the production of the major fimbrae protein FimA
NP_459545.1	in Salmonella typhimurium strs. LB5010 and SL1344 FimY is involved in the regulation of the fimbrial structural genes PMID:10816478
NP_459546.1	diguanylate cyclase/phosphodiesterase domain 0
NP_459547.1	in Salmonella typhimurium strs. LB5010 and SL1344 FimY is involved in the regulation of the fimbrial structural genes PMID:11133935
NP_459562.1	outer membrane esterase; N-acetyl phenylalanine beta-naphthyl esterase
NP_459570.1	catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive
NP_459573.1	resistance against oxidative stress protein A
NP_459575.1	ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity
NP_459576.1	EntD; phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex
NP_459577.1	Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space
NP_459580.1	with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin
NP_459581.1	part of the ferric enterobactin transport system; necessary for enetrobactin uptake
NP_459582.1	with FepBDE is involved in the transport of ferric enterobactin
NP_459583.1	with FepBCD is involved in the transport of ferric enterobactin
NP_459584.1	with FepBCG is involved in the transport of ferric enterobactin
NP_459585.1	protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters
NP_459586.1	with FepCDG is involved in the transport of ferric enterobactin
NP_459587.1	synthesizes isochorismate acid from chorismate
NP_459588.1	enterobactin synthase subunit E; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate
NP_459590.1	catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin
NP_459591.1	prevents misacylation of EntB in enterobactin synthesis
NP_459594.1	member of the iron-containing alcohol dehydrogenase family; unknown function
NP_459595.1	catalyzes the transfer of an amino moiety
NP_459597.1	PAPS reductase/FAD synthetase
NP_459599.1	Involved in disulfide bond formation
NP_459600.1	with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate
NP_459601.1	alkyl hydroperoxide reductase F52a subunit; detoxification of hydroperoxides
NP_459608.1	Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation
NP_459609.1	cleaves phosphodiester bond between any two nucleotides
NP_459611.1	catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA
NP_459612.1	2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate
NP_459615.1	acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate
NP_459618.1	regulates the expression of citAB in citrate fermentation
NP_459619.1	responsible for the transport of C4-dicarboxylates during anaerobic growth
NP_459620.1	catalyzes the transfer of palmitate to lipid A
NP_459621.1	member of the CspA family; negative regulator of cspA transcription; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator
NP_459622.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
NP_459624.1	TatE part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes
NP_459625.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
NP_459627.2	lipoate-protein ligase B; lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein
NP_459629.1	penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors
NP_459633.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
NP_459635.1	alpha-ribazole-5'-phosphate phosphatase (SW:COBC_SALTY); cobalamin synthesis
NP_459636.1	cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase
NP_459637.1	transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria
NP_459638.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
NP_459639.1	rare lipoprotein B; involved in the assembly of LPS in the outer membrane
NP_459640.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
NP_459643.1	transports degraded pectin products into the bacterial cell
NP_459646.1	TPR repeat
NP_459650.1	DnaJ family
NP_459653.1	Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific
NP_459658.1	Transfers the fatty acyl group on membrane lipoproteins
NP_459662.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
NP_459663.1	catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q
NP_459665.1	functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP
NP_459668.1	catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate
NP_459669.1	catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate
NP_459670.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
NP_459671.1	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_459672.1	required for uptake of chitin-derived oligosaccharides
NP_459674.1	is involved in the uptake of citrate and the transport of protons into the cell; also involved in the transport of tricarballylate
NP_459675.1	with CitA (TcuA) catalyzes the oxidation of tricarballylate to cis-aconitate; originally thought to be involved in citrate utilization
NP_459676.1	catalyzes the oxidation of tricarballylate to cis-aconitate; FAD-dependent; required for the utilization of tricarballylate as a carbon and energy source by S. enterica
NP_459678.1	negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer
NP_459679.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NP_459680.1	LexA-regulated
NP_459682.1	negative modulator of the initiation of chromosome replication
NP_459683.1	catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate
NP_459685.1	catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system
NP_459687.1	response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport
NP_459688.1	sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein
NP_459689.1	One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex
NP_459690.1	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
NP_459691.1	catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
NP_459692.1	one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
NP_459694.1	UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent
NP_459709.1	cell wall biogenesis
NP_459710.1	cell wall biogenesis
NP_459713.1	5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity
NP_459715.1	type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH
NP_459719.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol
NP_459720.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
NP_459721.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
NP_459722.1	component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA
NP_459723.1	catalyzes the interconversion of succinyl-CoA and succinate
NP_459724.1	Catalyzes the only substrate-level phosphorylation in the TCA cycle
NP_459729.1	catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components
NP_459730.1	membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins
NP_459731.1	membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins
NP_459732.1	inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins
NP_459733.1	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA
NP_459735.1	periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity
NP_459736.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
NP_459737.1	PNUC protein (SW:PNUC_SALTY); NMN family
NP_459738.1	involved in zinc efflux across the cytoplasmic membrane
NP_459740.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
NP_459742.1	Catalyzes the reversible hydration of fumaric acid to yield I-malic acid
NP_459746.1	catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide
NP_459747.1	oxaloacetate decarboxylase beta chain (SW:DCOB_SALTY)
NP_459751.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
NP_459752.1	catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose
NP_459753.1	catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism
NP_459754.1	catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P
NP_459755.1	UDP-glucose 4-epimerase (SW:GALE_SALTY)
NP_459757.1	contains 2 ATP-binding cassettes; involved in the transport of molybdenum
NP_459758.1	represses the modABCD operon and activates the moaABCD and napFDAGHBC operons
NP_459760.1	with ModCB is involved in the high-affinity transport of molybdate
NP_459761.1	part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE
NP_459762.1	Part of the ABC transporter complex modABC involved in molybdenum import
NP_459763.1	YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily
NP_459764.1	catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
NP_459765.1	outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family
NP_459766.1	catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway
NP_459767.1	catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate
NP_459769.1	catalyzes the degradation of histidine to urocanate and ammmonia
NP_459771.1	catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate
NP_459773.1	catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine
NP_459774.1	biotin biosynthesis protein BioC; methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth
NP_459775.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
NP_459776.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
NP_459778.1	leucine-rich repeat protein SlrP; secreted by SPI-1; type III secretion
NP_459780.1	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z
NP_459782.1	MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis
NP_459783.2	with MoaE catalyzes the conversion of molybdopterin precursor Z into molybdopterin
NP_459784.1	with MoaD catalyzes the conversion of molybdopterin precursor Z into molybdopterin
NP_459793.1	ABC superfamily membrane protein
NP_459794.1	ABC superfamily membrane protein
NP_459798.1	this helicase is not essential cell growth
NP_459799.1	helicase involved in DNA repair and perhaps also replication
NP_459808.1	binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage
NP_459809.1	hypothetical protein in dps-ompX intergenic region (SW:YBIF_SALTY)
NP_459810.1	OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains
NP_459812.1	Transcriptional regulator that represses the manganese transporter MntH when manganese is present
NP_459819.1	HAD superfamily
NP_459822.1	ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase
NP_459823.2	is involved in the formation of active molybdenum cofactor and the chelation of molybdenum
NP_459825.1	with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains
NP_459829.1	catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit
NP_459830.1	BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing
NP_459840.1	penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains
NP_459849.1	functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase
NP_459850.1	YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function
NP_459851.1	NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds
NP_459852.1	responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6
NP_459855.1	part of the PotFGHI ATP-dependent putrescine transporter
NP_459859.1	RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA
NP_459860.1	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
NP_459864.1	with ArtPQJI acts to transport arginine across the inner membrane
NP_459865.1	with ArtPMJI transports arginine across the inner membrane
NP_459867.1	With ArtMQJI transports arginine across the inner membrane
NP_459868.1	induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS
NP_459885.1	bacteriophage ES18 gp15 protein
NP_459905.1	neuraminidase
NP_459911.1	low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine
NP_459912.1	catalyzes the formation of acetate from pyruvate
NP_459914.1	catalyzes the reduction of hydroxylamine to ammonia and water
NP_459918.1	confers macrolide resistance via active drug efflux
NP_459919.1	with MacA is involved in the export of macrolide
NP_459921.1	involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA
NP_459922.1	ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates
NP_459923.1	transposase for insertion sequence element IS200 (SW:T200_SALTY)
NP_459929.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
NP_459931.1	leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys
NP_459932.1	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c
NP_459933.1	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c
NP_459934.1	catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding
NP_459935.1	mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system
NP_459936.1	DNA-binding membrane protein required for chromosome resolution and partitioning
NP_459937.1	participates with LolB in the incorporation of lipoprotein into the outer membrane
NP_459939.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_459945.2	activates pyruvate formate-lyase 1 under anaerobic conditions
NP_459952.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
NP_459953.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
NP_459955.1	Catalyzes the formation of (d)CDP from ATP and (d)CMP
NP_459956.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
NP_459957.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
NP_459959.1	involved in the transport of lipid A across the inner membrane
NP_459960.1	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate
NP_459963.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
NP_459967.1	condesin subunit F; acts with MukB and MukE to condense the chromosome and allow for segregation during cell division
NP_459968.1	condesin subunit E; acts with MukB and MukF to condense the chromosome and allow for segregation during cell division
NP_459969.1	SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects
NP_459973.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
NP_459974.1	outer membrane protein F precursor; porin; (SW:OMPF_SALTY)
NP_459975.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_459977.1	catalyzes the formation of pyruvate from 2,3-diaminopropionate
NP_459979.1	catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate
NP_459987.1	probable regulatory protein
NP_459988.1	probable regulatory protein
NP_459989.1	probable replication protein
NP_459990.1	acts to load the DnaB helicase onto the intiation site durning DNA replication
NP_459997.1	DnaJ family
NP_460004.1	bacteriophage ES18 gp15 protein
NP_460019.1	superoxide dismutase CuZn (SW:SODC_SALTY); important virulence function; implicated in defence against macrophage killing
NP_460026.1	required for maintaining a long-term systemic infection; secreted effector I; secreted by SPI-2; colocalizes with host polymerizing actin cytoskeleton
NP_460032.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
NP_460035.1	RimK and RimL; catalyzes the N2-methyl guanosine modification of the G2445 residue and G2079 residue of 23S rRNA
NP_460036.1	Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth
NP_460041.1	catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP
NP_460044.1	OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d
NP_460045.1	suppressor of lon (SW:SULA_SALTY); inhibitor of cell division and FtsZ ring formation upon DNA damage/inhibition; HslVU and Lon involved in its turnover
NP_460047.1	efflux PET family
NP_460049.1	catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand
NP_460050.1	catalyzes the formation of methylglyoxal from glycerone phosphate
NP_460057.1	catalyzes the hydrolysis of acylphosphate
NP_460058.1	transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs
NP_460061.1	secreted effector protein PipB; similar to STM2780; secreted by SPI-2; type III secretion; localizes to Salmonella-containing vacuole and host cell membranes
NP_460064.1	SigD; Salmonella outer protein B; similar to ipgD of Shigella; invasion gene D protein; secreted by SPI-1; type III secretion
NP_460067.1	pathogenicity island-encoded protein D
NP_460069.2	induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced
NP_460083.1	sigma S-regulator; RssC
NP_460084.1	with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA
NP_460085.1	functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock
NP_460086.1	suppressor for copper-sensitivity A; copper binding protein
NP_460087.1	suppressor for copper-sensitivity B; suppression of copper sensitivity
NP_460088.1	suppressor for copper-sensitivity C; suppression of copper sensitivity
NP_460089.1	suppressor for copper-sensitivity D; suppression of copper sensitivity
NP_460097.1	sodium/proline symporter proline permease (SW:PUTP_SALTY); SSS family
NP_460101.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
NP_460109.1	hypothetical protein in phoH-csgG intergenic region (SW:YCDZ_SALTY)
NP_460110.1	curli production assembly/transport component CsgG (SW:CSGG_SALTY)
NP_460111.1	nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex
NP_460112.1	chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex
NP_460113.1	activates the csgBA and csgDEFG operons involved in biofilm formation
NP_460114.1	CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface
NP_460115.1	major curlin subunit precursor; fimbrin SEF17 (SW:CSGA_SALTY); coiled surface structures; cryptic
NP_460116.1	involved in autoagglutination of curliated cells; not involved in production of curli fibers
NP_460117.1	hypothetical protein in csgC-mdoG intergenic region (SW:YMDA_SALTY)
NP_460120.1	required for the transfer of succinyl residues to the glucan backbone
NP_460121.1	involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan
NP_460122.1	necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space
NP_460125.1	Confers resistance to fosfomycin and deoxycholate
NP_460126.1	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA
NP_460131.1	catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids
NP_460132.3	BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing
NP_460134.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
NP_460135.1	hypothetical protein in pyrC 3'region (SW:YCEB_SALTY)
NP_460136.1	cofactor involved in the reduction of disulfides
NP_460137.1	Confers resistance to norfloxacin and enoxacin
NP_460138.1	acetylates N-terminal alanine of 30S ribosomal subunit protein S5
NP_460141.1	involved in murein biosynthesis
NP_460142.1	flagella synthesis protein FlgN (SW:FLGN_SALTY)
NP_460143.1	regulates the flagellar specific sigma28 transcription factor
NP_460144.1	required for the assembly of the flagellar basal body P-ring
NP_460145.1	with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella
NP_460146.1	with FlgF and B makes up the proximal portion of the flagellar basal body rod
NP_460147.1	acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production
NP_460148.1	the hook connects flagellar basal body to the flagellar filament
NP_460149.1	FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod
NP_460150.1	makes up the distal portion of the flagellar basal body rod
NP_460151.1	part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod
NP_460152.1	part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum
NP_460153.1	flagellar rod assembly protein; Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space
NP_460154.1	with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook
NP_460155.1	with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes
NP_460156.1	bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase
NP_460157.1	catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA
NP_460159.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
NP_460160.1	hypothetical protein in rne-rpmF intergenic region (G30K) (SW:YCED_SALTY)
NP_460161.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
NP_460162.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
NP_460163.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
NP_460164.1	malonyl coA-acyl carrier protein transacylase (SW:FABD_SALTY)
NP_460165.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NP_460166.1	carries the fatty acid chain in fatty acid biosynthesis
NP_460167.1	FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
NP_460168.1	catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate
NP_460170.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
NP_460171.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
NP_460173.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
NP_460178.1	catalyzes the phosphorylation of thiamine to thiamine phosphate
NP_460179.1	hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
NP_460183.1	TetR/AcrR family
NP_460187.2	part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane
NP_460188.1	outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone
NP_460189.1	part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane
NP_460190.1	catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine
NP_460191.1	Modulates the activities of several enzymes which are inactive in their acetylated form
NP_460192.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate
NP_460193.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component
NP_460194.1	translocated by the type III secretion system SPI-2; required for the formation of lysosomal glycoprotein structures (Sifs); required for maintenance of membrane in the Salmonella-containing vacuole; a cysteine residue with CAAX motif is modified by isoprenoid addition of protein geranylgeranyl transferase I; also modified by S-acylation
NP_460195.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component
NP_460196.1	functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase
NP_460197.1	catalyzes the release of the N-terminal amino acid from a tripeptide
NP_460200.1	virulence sensor protein PhoQ (SW:PHOQ_SALTY); in two-component regulatory system with PhoP; ligand is Mg+
NP_460201.1	response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress
NP_460202.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
NP_460203.1	HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis
NP_460204.2	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
NP_460208.1	Converts isocitrate to alpha ketoglutarate
NP_460210.1	probable lipoprotein EnvF (SW:ENVF_SALTY)
NP_460211.1	macrophage survival protein; reduced mouse virulence
NP_460212.1	probable lipoprotein EnvE (SW:ENVE_SALTY)
NP_460213.1	cold shock-like protein CspH (SW:CSPH_SALTY)
NP_460214.1	(SW:PAGD_SALTY); PhoP regulated protein
NP_460215.1	(SW:PAGC_SALTY); PhoP regulated; reduced macrophage survival
NP_460216.1	PliC; periplasmic lysozyme inhibitor of c-type lysozyme
NP_460222.1	substrate-binding protein
NP_460223.1	transmembrane protein
NP_460224.1	transmembrane protein
NP_460225.1	ATPase; contain duplicated ATPase domain
NP_460226.1	ATPase; contains duplicated ATPase domain
NP_460230.1	streptomycin 3'-adenyltransferase
NP_460231.1	contains CheY-like receiver domain and HTH DNA-binding domain
NP_460235.1	catalyzes the interconversion of chorismate to prephenate
NP_460249.1	contains diguanylate cyclase/phosphodiesterase domain 1
NP_460252.1	scaffolding protein for murein-synthesizing holoenzyme
NP_460256.1	catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate
NP_460257.1	this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress
NP_460259.1	catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide
NP_460260.1	converts asparagine to aspartate and ammonia
NP_460261.1	SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane
NP_460263.1	catalyzes the formation of selenophosphate from selenide and ATP
NP_460264.1	decatenates replicating daughter chromosomes
NP_460265.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
NP_460268.1	removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction
NP_460269.1	catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate
NP_460271.1	a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH
NP_460272.1	catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation
NP_460273.1	catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism
NP_460274.1	periplasmic protein induced by stress response via Cpx and BaeSR system
NP_460275.1	3' incision activity; acts with UvrC
NP_460276.1	catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
NP_460277.1	osmotically-inducible lipoprotein E; activator of ntr-like gene protein
NP_460278.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
NP_460279.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
NP_460280.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
NP_460281.1	represses the celABCDF-ydjC operon involved in carbon uptake
NP_460284.1	Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide
NP_460285.1	affects inhibition after overreplication of chromosome in dnaAcos mutants
NP_460287.2	LexA-regulated gene
NP_460288.1	YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate
NP_460293.1	salt-inducible
NP_460298.1	O-antigen polymerase (SW:RFC_SALTY)
NP_460299.1	catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_460300.2	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
NP_460302.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
NP_460303.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
NP_460304.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
NP_460305.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
NP_460306.1	with BtuD and BtuF transports vitamin B12 into the cell
NP_460308.1	ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell
NP_460310.1	diguanylate cyclase/phosphodiesterase domain 1
NP_460313.1	tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate
NP_460315.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
NP_460316.1	acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids
NP_460319.1	May play a role in a redox process
NP_460320.1	YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain
NP_460322.1	may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain
NP_460324.1	catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis
NP_460325.1	YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate
NP_460329.1	YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function
NP_460331.1	possibly involved in aromatic compounds catabolism; PaaI
NP_460334.1	functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer
NP_460335.1	with SufCD activates cysteine desulfurase SufS
NP_460336.1	part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE
NP_460337.1	with SufBC activates cysteine desulfurase SufS
NP_460338.1	catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine
NP_460339.1	Acts with SufS to catalyze the formation of L-alanine from L-cysteine
NP_460343.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
NP_460345.1	hydrolase or acyltransferase
NP_460348.1	tetrathionate reductase subunit A; TtrA
NP_460349.1	tetrathionate reductase subunit C; TtrC
NP_460350.1	tetrathionate reductase subunit B; TtrB
NP_460351.1	tetrathionate reductase complex; TtrS; two-component regulatory system
NP_460352.2	tetrathionate reductase complex; TtrR; two-component regulatory system
NP_460353.1	hypothetical 7.9 kDa protein in ssrB-ttRr intergenic region (ORF70) (SW:YDHZ_SALTY)
NP_460357.1	SpiR; type III secretion system regulator; regulated by OmpR-EnvZ
NP_460358.1	SpiC; effects secretion of other SPI-2 proteins; interacts with host cell TassC and Hook3 proteins; type III secretion; prevents fusion of endosome/lysosome with Salmonella-containing vacuoles
NP_460359.1	SpiA; type III secretion system apparatus
NP_460360.1	SpiB; type III secretion system
NP_460361.1	secretory apparatus component
NP_460362.1	Salmonella typhimurium SseA; chaperones SseB/D
NP_460363.1	secreted protein
NP_460364.1	secretion chaperone
NP_460365.1	SseC
NP_460366.1	SseD
NP_460367.1	SseE
NP_460368.1	SscB
NP_460369.1	SseF
NP_460370.1	SseG
NP_460371.1	SsaH
NP_460372.1	SsaH
NP_460373.1	SsaI
NP_460374.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460376.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460377.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460378.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460379.1	with SsaC forms part of a protein export system across the inner and outer cell membranes; member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460380.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460381.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460382.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460383.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460384.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460385.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460386.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460387.1	member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli involved in the infection of eukaryotic cells; gene expression shown in other strains of S. typhimurium PMID:9140973
NP_460388.1	NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones
NP_460389.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
NP_460390.1	catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge
NP_460391.1	uncharacterized member of the major facilitator superfamily (MFS)
NP_460393.1	binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers
NP_460394.1	SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals
NP_460397.1	Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A)
NP_460398.1	Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione
NP_460399.1	FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide
NP_460400.1	TetR/AcrR family
NP_460403.1	SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water
NP_460407.2	Transcription regulator that can both activate or repress expression
NP_460408.1	outer membrane lipoprotein SlyB (SW:SLYB_SALTY)
NP_460409.1	catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling
NP_460410.1	MliC; membrane-bound lysozyme inhibitor of c-type lysozyme
NP_460411.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate
NP_460412.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
NP_460413.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal
NP_460415.1	mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation
NP_460416.1	DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines
NP_460417.1	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase
NP_460418.1	part of membrane-bound complex hought to be involved in electron transport to nitrogen
NP_460419.1	RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents
NP_460420.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
NP_460421.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
NP_460422.1	inner membrane protein
NP_460424.3	YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes
NP_460426.1	catalyzes the formation of inosine from adenosine
NP_460428.1	mannose-6-phosphate isomerase (SW:MANA_SALTY)
NP_460429.1	fumarate hydratase class I aerobic isozyme (SW:FUMA_SALTY)
NP_460430.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
NP_460431.1	binds to DNA replication terminator sequences to prevent passage of replication forks
NP_460435.1	response regulator in two-component regulatory system with RstB
NP_460439.1	forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm
NP_460440.1	catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme
NP_460441.1	transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes
NP_460442.1	with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS
NP_460443.1	with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS
NP_460445.2	required for growth and survival under moderately acid conditions
NP_460449.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
NP_460455.1	binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane
NP_460465.1	tarvation sensing protein RpsA
NP_460470.1	GntR family
NP_460471.1	NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine
NP_460472.1	peptidyl-dipeptidase DCP (SW:DCP_SALTY)
NP_460476.1	YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters
NP_460479.3	transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF
NP_460480.1	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
NP_460481.1	in E.coli K-12 this protein is not involved in antibiotic resistance
NP_460484.1	in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase
NP_460485.1	catalyzes the formation of glutamate from glutamine
NP_460496.1	processing of HyaA and HyaB proteins
NP_460507.1	marR-family
NP_460520.1	outer membrane or secreted
NP_460524.1	protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase
NP_460525.1	malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate
NP_460527.1	nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase
NP_460533.1	methyl viologen resistance protein SmvA (SW:SMVA_SALTY)
NP_460534.1	TetR family
NP_460535.1	MFS superfamily
NP_460541.1	N-hydroxyarylamine O-acetyltransferase (SW:NHOA_SALTY)
NP_460547.1	GntR family
NP_460552.1	SrfA; ssrAB-activated gene
NP_460553.1	SrfB ; ssrAB-activated gene
NP_460554.1	SrfC; contains predicted coiled-coil structure; ssrAB-activated gene
NP_460556.2	catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation
NP_460558.1	D-alanyl-D-alanine dipeptidase for peptidoglycan digestion
NP_460561.1	translocated by the type III secretion system SPI-2; localizes to Sifs in infected cells and specifically to Salmonella-containing vacuoles
NP_460564.1	oxidoreductase
NP_460567.1	with TehA confers resistance to tellurite
NP_460569.1	involved in lipopolysaccharide biosynthesis
NP_460576.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
NP_460581.1	involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans
NP_460590.1	deacylase activity; secreted effector J; Salmonella translocated effector; regulated by SPI-2
NP_460598.1	B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm
NP_460600.3	involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain
NP_460601.1	FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds
NP_460606.1	Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes
NP_460613.1	TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs
NP_460614.1	exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA
NP_460617.1	contains Smr domain
NP_460618.1	O-6-alkylguanine-DNA:cysteine-protein methyltransferase
NP_460619.2	Global transcription factor that controls the expression of over 100 target genes in response to anoxia
NP_460620.1	with UspC and UspD is involved in resistance to UV irradiation
NP_460632.1	AraC family; helix-turn-helix
NP_460640.1	antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein
NP_460641.1	regulates genes involved in the biosynthesis and transport of aromatic amino acids
NP_460644.1	rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide
NP_460646.1	with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock
NP_460647.1	acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding
NP_460648.1	involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF
NP_460649.1	transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor
NP_460650.1	peptide transport periplasmic protein SapA (SW:SAPA_SALTY); ABC superfamily periplasmic protein
NP_460651.1	peptide transport system permease protein SapB (SW:SAPB_SALTY); ABC superfamily membrane protein
NP_460652.1	peptide transport system permease protein SapC (SW:SAPC_SALTY); ABC superfamily membrane protein
NP_460653.1	peptide transport system atp-binding protein SapD (SW:SAPD_SALTY); ABC superfamily ATP-binding protein
NP_460654.1	peptide transport system atp-binding protein SapF (SW:SAPF_SALTY); ABC superfamily ATP-binding protein
NP_460655.1	diguanylate cyclase/phosphodiesterase domain 2
NP_460657.1	e6 protein
NP_460658.1	hypothetical 10.4 kDa protein in fabI/envM 5'region (SW:YCJE_SALTY)
NP_460659.1	Catalyzes a key regulatory step in fatty acid biosynthesis
NP_460661.1	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NP_460662.1	c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP
NP_460665.1	involved in start site selection during the initiation of translation
NP_460666.1	OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
NP_460670.1	catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate
NP_460671.1	Catalyzes the conversion of citrate to isocitrate
NP_460672.1	LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation
NP_460673.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
NP_460675.1	SohB; periplasmic protein; member of the peptidase S49 family
NP_460677.1	catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide
NP_460678.1	catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA
NP_460679.1	translation factor
NP_460680.1	TrpH protein (SW:TRPH_SALTY); TrpR controlled transcriptional unit in the 5' upstream region of the trp operon
NP_460682.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
NP_460683.1	bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis
NP_460684.1	monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate
NP_460685.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
NP_460686.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
NP_460691.1	receptor for colicin S4
NP_460694.1	Involved in cell division; probably involved in intracellular septation
NP_460695.1	YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins
NP_460696.1	membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of iron-siderophore complexes, vitamin B12 and colicins
NP_460697.1	unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity
NP_460698.1	catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol)
NP_460701.1	oligopeptide transport ATP-binding protein; OppF (SW:OPPF_SALTY); ABC superfamily ATP-binding protein
NP_460702.1	oligopeptide transport ATP-binding protein OppD (SW:OPPD_SALTY); ABC superfamily ATP-binding protein
NP_460703.1	oligopeptide transport system permease protein OppC (SW:OPPC_SALTY); ABC superfamily membrane protein
NP_460704.1	oligopeptide transport system permease protein OppB (SW:OPPB_SALTY); ABC superfamily membrane protein
NP_460705.2	periplasmic oligopeptide-binding protein (SW:OPPA_SALTY); ABC superfamily periplasmic protein; contains chaperone properties
NP_460709.1	catalyzes the formation of thymidine 5'-phosphate from thymidine
NP_460710.1	DNA-binding protein H-NS; histone-like protein HLP-II; protein H1; protein B1 (SW:HNS_SALTY); HU; BH2; HD; NS; pleiotropic regulator
NP_460711.1	together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose
NP_460715.1	produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine
NP_460716.1	contains TPR repeats
NP_460723.1	two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase
NP_460726.1	in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions
NP_460728.1	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis
NP_460730.1	regulation of invasion genes
NP_460731.1	HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB
NP_460732.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
NP_460733.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
NP_460734.1	Incorporates lipoproteins in the outer membrane after they are released by the LolA protein
NP_460735.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
NP_460736.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
NP_460737.2	transports mono and dicarboxylates; member of the SulP family of sulfate transporters
NP_460738.1	YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function
NP_460739.2	Enables the recycling of peptidyl-tRNAs produced at termination of translation
NP_460740.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
NP_460743.1	involved in hydrogen cycling during fermentative growth
NP_460745.1	HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1)
NP_460746.1	involved in processing hydrogenase proteins HyaA and HyaB
NP_460750.1	expressed during stationary phase
NP_460752.1	periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell
NP_460754.1	Cyclic di-GMP binding protein
NP_460756.1	catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine
NP_460757.1	the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli
NP_460758.1	catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA
NP_460759.1	catalyzes the oxidative deamination of D-amino acids
NP_460761.1	Multifunctional regulator of fatty acid metabolism
NP_460762.1	involved in regulation of intracellular pH under alkaline conditions
NP_460763.1	disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein
NP_460770.1	blocks the formation of polar Z-ring septums
NP_460771.1	ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums
NP_460772.1	works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell
NP_460774.1	Activates fatty acids by binding to coenzyme A
NP_460779.1	hypothetical protein in fadD-pabB intergenic region (SW:YOAH_SALTY)
NP_460780.1	catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine
NP_460781.1	hypothetical protein in pabB-sdaA intergenic region (SW:YEAB_SALTY)
NP_460788.1	phosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel
NP_460790.1	membrane protein YebN
NP_460791.1	methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth
NP_460793.1	cold shock-like protein CspC (SW:CSPC_SALTY); multicopy suppresses mukB mutants; regulator
NP_460795.1	periplasmic protein
NP_460800.1	metalloprotease
NP_460801.1	Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3
NP_460802.1	affects solute and DNA transport through an unknown mechanism
NP_460806.1	in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA
NP_460809.1	Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins
NP_460811.1	SopE2; invasion-associated protein; secreted by SPI-1; interacts with chaperone InvB; guanine nucleotide exchange factor for Cdc42; activates Cdc42 which results in actin cytoskeleton rearrangements and internalization
NP_460818.1	PagO protein (SW:PAGO_SALTY); PhoPQ-activated gene
NP_460822.1	PhoPQ-activated gene
NP_460823.1	phage tail assembly protein
NP_460830.1	periplasmic protein
NP_460835.1	3'-5' exonuclease activity on single or double-strand DNA
NP_460836.1	PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues
NP_460838.1	secreted protein; unknown function
NP_460839.1	in SOS regulon; dependent on cyclic AMP and H-NS
NP_460840.1	non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis
NP_460841.1	catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate
NP_460842.1	catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate
NP_460843.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
NP_460844.1	Represses the expression of the zwf, eda, glp and gap
NP_460845.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
NP_460846.1	Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA
NP_460848.2	involved in transport of zinc(II) with ZnuA and C
NP_460849.2	involved in transport of zinc(II) with ZnuA and C
NP_460850.1	involved in transport of zinc(II) with ZnuA and C
NP_460851.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
NP_460852.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
NP_460855.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
NP_460857.1	converts dATP to dAMP and pyrophosphate
NP_460858.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
NP_460866.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
NP_460867.1	penicillin-binding protein 2; PBP-2 (SW:PBP2_SALTY)
NP_460869.1	flagellar protein FlhE (SW:FLHE_SALTY)
NP_460870.1	membrane protein involved in the flagellar export apparatus
NP_460871.1	membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export
NP_460872.1	cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation
NP_460873.1	chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble
NP_460874.1	regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins
NP_460875.1	methylates the MCP
NP_460876.1	methyl-accepting chemotaxis protein II; MCP-II (SW:MCP2_SALTY); aspartate sensor-receptor
NP_460877.1	chemotaxis protein CheW (SW:CHEW_SALTY); regulation; couples CheA histidine kinase to transducers
NP_460878.1	chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component
NP_460879.1	with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
NP_460880.1	With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
NP_460881.2	With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems
NP_460882.1	with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems
NP_460884.1	ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress
NP_460886.1	biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature
NP_460891.1	cytoplasmic iron storage protein
NP_460899.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NP_460900.1	in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system
NP_460903.1	regulates genes involved in cell division
NP_460906.1	catalyzes the formation of pyruvate from D-cysteine
NP_460908.1	expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence
NP_460909.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes
NP_460910.2	transposase for insertion sequence element is200 (SW:T200_SALTY)
NP_460911.1	N-methylation of lysine residues in flagellin (SW:FLIB_SALTY)
NP_460912.1	structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes
NP_460913.1	involved in flagellin assembly
NP_460914.1	flagellin specific chaperone
NP_460915.1	binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family
NP_460916.1	converts 1,4-alpha-D-glucans to maltodextrin
NP_460917.1	15.5 kDa protein in amyA-fliE intergenic region (SW:YEDD_SALTY)
NP_460918.2	hypothetical 44.2 kDa protein in amyA-fliE intergenic region (SW:YEDE_SALTY); component of transport system
NP_460919.1	hypothetical 8.6 kDa protein in amyA-fliE intergenic region; ORF 9 (SW:YEDF_ECOLI)
NP_460921.1	forms a junction between the M-ring and FlgB during flagella biosynthesis
NP_460922.1	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
NP_460923.1	One of three proteins involved in switching the direction of the flagellar rotation
NP_460924.1	binds to and inhibits the function of flagella specific ATPase FliI
NP_460925.1	involved in type III protein export during flagellum assembly
NP_460926.1	rod/hook and filament chaperone
NP_460927.1	flagellar hook-length control protein (SW:FLIK_SALTY)
NP_460928.1	interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring
NP_460929.1	with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation
NP_460930.1	One of three proteins involved in switching the direction of the flagellar rotation
NP_460931.2	with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus
NP_460932.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
NP_460933.1	with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus
NP_460934.1	FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus
NP_460935.1	positive transcriptional regulator of capsular/exo-polysaccharide synthesis; LuxR/UhpA family (SW:RCSA_SALTY)
NP_951051.1	downstream region B; regulated by DsrA and HNS, under control of RpoS
NP_460937.1	catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate
NP_460948.1	binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization
NP_460949.1	binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization
NP_460954.1	contains TPR repeats
NP_460956.1	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile
NP_460959.1	MATE family
NP_460961.1	catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole
NP_460962.1	catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole
NP_460963.1	catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP
NP_460964.1	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NP_460965.1	with CbiNQ forms the ABC transporter for cobalt import
NP_460966.1	cobalt transport protein CbiQ (SW:CBIQ_SALTY)
NP_460967.1	periplasmic cobalt binding component of the cobalt transport system
NP_460968.2	catalyzes the ATP-dependent transport of cobalt
NP_460969.1	catalyzes the formation of precorrin-3A from precorrin-2
NP_460970.1	cobalt chelatase (SW:CBIK_SALTY)
NP_460971.1	CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6
NP_460972.1	catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine
NP_460973.1	catalyzes the formation of cobalt-precorrin 5B from cobalt-precorrin 5A; protein characterization on unidentifed S. typhimurium strain PMID:16866557
NP_460975.1	catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W; decarboxylating
NP_460976.1	catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a
NP_460977.1	Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A
NP_460978.1	catalyzes the interconversion of cobalt-precorrin-8X and cobyrinic acid in the anaerobic biosynthesis of cobalamin
NP_460979.1	CobD; CbiB in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NP_460980.1	responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid
NP_460981.1	regulatory protein PocR (SW:POCR_SALTY); propanediol utilization protein; AraC family
NP_460982.1	propanediol diffusion facilitator (SW:PDUF_SALTY); propanediol utilization protein
NP_460983.1	propanediol utilization protein PduA (SW:PDUA_SALTY); propanediol utilization protein
NP_460984.2	propanediol utilization protein PduB (SW:PDUB_SALTY); propanediol utilization protein
NP_460985.1	glycerol dehydratase large subunit (SW:DHAB_SALTY); propanediol utilization protein
NP_460986.1	propanediol utilization protein
NP_460987.1	propanediol utilization protein
NP_460988.1	propanediol utilization protein
NP_460989.1	propanediol utilization protein
NP_460995.1	related to B12-dependent glycerol dehydratase
NP_461000.1	propanediol utilization protein PduU (SW:PDUU_SALTY); propanediol utilization protein
NP_461001.1	propanediol utilization protein PduV (SW:PDUV_SALTY)
NP_461002.1	involved in coenzyme B(12)-dependent 1, 2-propanediol degradation; important for the synthesis of propionyl coenzyme A during growth on 1,2-propanediol
NP_461003.1	Propanediol utilization protein PduX
NP_461007.1	removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains
NP_461008.1	membrane-anchoring protein (SW:PHSC_SALTY); hydrogen sulfide production
NP_461009.1	PhsB (SW:PHSB_SALTY); hydrogen sulfide production; iron-sulfur subunit; electron transfer
NP_461010.1	membrane-anchoring protein (SW:PHSA_SALTY); hydrogen sulfide production
NP_461012.1	Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
NP_461016.1	long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors
NP_461017.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
NP_461018.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
NP_461019.1	catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate
NP_461020.2	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
NP_461021.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
NP_461022.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
NP_461023.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis
NP_461024.1	chain length determinant protein; polysaccharide antigen chainregulator (SW:WZZB_SALTY); regulator of length of O-antigen component of lipopolysaccharide chains
NP_461025.1	UDP-glucose 6-dehydrogenase (SW:UDG_SALTY)
NP_461026.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
NP_461027.1	undecaprenyl-phosphate galactosephosphotransferase (SW:RFBP_SALTY); mutation results in LPS side chain defect
NP_461028.1	phosphomannomutase (SW:RFBK_SALTY); LPS side chain defect
NP_461029.1	mannose-1-phosphate guanylyltransferase GDP (SW:RFBM_SALTY); LPS side chain defect
NP_461030.1	rhamnosyltransferase RfbN (SW:RFBN_SALTY); LPS side chain defect
NP_461031.1	RFBU protein (SW:RFBU_SALTY); LPS side chain defect
NP_461032.1	RFBV protein (SW:RFBV_SALTY); LPS side chain defect
NP_461033.1	O-antigen transporter (SW:RFBX_SALTY); LPS side chain defect
NP_461034.1	CDP-abequose synthase (SW:RFBJ_SALTY); LPS side chain defect
NP_461035.1	lipopolysaccharide biosynthesis protein RfbH (SW:RFBH_SALTY); LPS side chain defect
NP_461036.1	CDP-glucose 4,6-dehydratase (SW:RFBG_SALTY); LPS side chain defect
NP_461037.1	glucose-1-phosphate cytidylyltransferase (SW:RFBF_SALTY); LPS side chain defect
NP_461038.1	catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose
NP_461039.1	DTDP-4-dehydrorhamnose 3,5-epimerase (SW:RFBC_SALTY)
NP_461041.1	with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose
NP_461042.1	NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose
NP_461043.1	together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose
NP_461044.1	WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid
NP_461045.1	in colanic acid biosynthesis gene cluster
NP_461048.1	WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid
NP_461049.1	phosphomannomutase in colanic acid gene cluster (SW:MANB_SALTY)
NP_461050.2	mannose-1-phosphate guanylyltransferase; GDP (SW:MANC_SALTY); in colanic acid gene cluster
NP_461055.1	acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit)
NP_461057.1	essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance
NP_461059.1	acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium
NP_461061.1	Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide)
NP_461062.1	Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis
NP_461065.1	YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs
NP_461066.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
NP_461067.1	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor
NP_461069.1	inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine
NP_461071.1	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate
NP_461072.1	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate
NP_461073.1	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate
NP_461076.1	response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport
NP_461084.1	cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role
NP_461085.1	catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate
NP_461090.1	catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine
NP_461091.1	catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP
NP_461099.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
NP_461101.1	hypothetical 16.9 kDa lipoprotein precursor
NP_461103.1	unknown function; when overproduced it confers drug-resistance
NP_461111.1	periplasmic beta-glucosidase (SW:BGLX_SALTY)
NP_461112.1	component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent
NP_461113.1	specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7
NP_461115.1	DedA family
NP_461117.1	may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
NP_461120.1	catalyzes the formation of catechol from salicylate
NP_461128.1	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
NP_461132.1	catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines
NP_461133.1	ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex
NP_461134.1	with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains
NP_461135.1	D-galactose-binding periplasmic protein precursor; GDP; D-galactose/D-glucose binding protein; GGBP (SW:DGAL_SALTY); ABC superfamily periplasmic protein
NP_461136.1	negative regulator of the mglBAC operon for galactose utilization
NP_461138.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
NP_461144.1	Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein
NP_461148.1	Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues
NP_461149.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
NP_461150.1	converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers
NP_461151.1	phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr
NP_461155.2	Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein
NP_461158.1	by similarity, Spr seems to have peptidase activity; involved in thermoresistance
NP_461159.1	involved in resistance to lambda and N4 phages
NP_461165.1	Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance
NP_461166.1	catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA
NP_461168.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
NP_461170.1	present in spermidine nucleoids
NP_461172.1	hypothetical protein in rplY-proL intergenic region (SW:YEJM_SALTY); alkaline phosphatase superfamily
NP_461175.1	O-antigen five; acetylation of the O-antigen (LPS)
NP_461184.1	induced by the SPI-2 regulator ssrA/B; secreted by SPI-2
NP_461189.1	nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes
NP_461191.1	thiol:disulfide interchange protein DsbE
NP_461193.1	CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane
NP_461197.1	ATP-binding protein; required for proper cytochrome c maturation
NP_461198.1	with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone
NP_461199.1	small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA
NP_461200.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA
NP_461201.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway
NP_461202.1	periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC
NP_461204.1	Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.
NP_461205.1	serine protease inhibitor, inhibits trypsin and other proteases
NP_461206.1	efflux pump for the antibacterial peptide microcin J25
NP_461207.1	alkylated DNA repair protein ALKB; specific for alkylated DNA
NP_461208.1	ADA regulatory protein; regulatory protein of adaptative response; (SW:ADA_SALTY); AraC/Xyl family
NP_461209.1	catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway
NP_461210.1	allows for ions and hydrophilic solutes to cross the outer membrane
NP_461211.1	in two-component regulatory system with RcsBC
NP_461212.1	two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF
NP_461213.1	in two-component regulatory system with RcsB and RscD
NP_461214.1	negatively supercoils closed circular double-stranded DNA
NP_461217.2	GntR family
NP_461218.1	Involved in ubiquinone biosynthesis
NP_461219.1	Catalyzes the rate-limiting step in dNTP synthesis
NP_461220.1	B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA
NP_461221.1	plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases
NP_461223.1	LysR family
NP_461224.1	hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic
NP_461225.1	catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell
NP_461226.1	anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor
NP_461227.1	sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters
NP_461228.1	anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate
NP_461229.2	specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system
NP_461239.2	catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose
NP_461240.1	catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate
NP_461241.1	Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains
NP_461243.1	catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A
NP_461246.1	polymyxin b resistance protein PmrD (SW:PMRD_SALTY)
NP_461247.1	O-succinylbenzoic acid-CoA ligase (SW:MENE_SALTY)
NP_461248.1	catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate
NP_461249.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
NP_461250.1	catalyzes the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate; and can also catalyze the hydrolysis of the thioester bond in palmitoyl-CoA
NP_461251.1	SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis
NP_461252.1	synthesizes isochorismate acid from chorismate
NP_461255.1	member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions
NP_461257.1	von Willebrand factor; contains vWF type A domain
NP_461258.2	Catalyzes the transfer of electrons from NADH to quinone
NP_461259.1	Catalyzes the transfer of electrons from NADH to quinone
NP_461260.1	Catalyzes the transfer of electrons from NADH to ubiquinone
NP_461261.1	Catalyzes the transfer of electrons from NADH to quinone
NP_461262.1	Catalyzes the transfer of electrons from NADH to quinone
NP_461263.1	Catalyzes the transfer of electrons from NADH to quinone
NP_461264.1	Catalyzes the transfer of electrons from NADH to quinone
NP_461265.2	Catalyzes the transfer of electrons from NADH to quinone
NP_461266.1	shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase
NP_461267.1	Catalyzes the transfer of electrons from NADH to quinone
NP_461268.1	NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms
NP_461269.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
NP_461270.1	Catalyzes the transfer of electrons from NADH to quinone
NP_461273.1	broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor
NP_461279.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
NP_461280.1	catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate
NP_461284.2	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
NP_461293.1	histidine transport ATP-binding protein HisP (SW:HISP_SALTY); ABC superfamily ATP-binding protein
NP_461294.1	histidine transport system permease protein HisM (SW:HISM_SALTY); ABC superfamily membrane protein
NP_461295.1	histidine transport system permease protein HisQ (SW:HISQ_SALTY); ABC superfamily membrane protein
NP_461296.1	histidine-binding periplasmic protein precursor; HBP (SW:HISJ_SALTY); ABC superfamily binding protein
NP_461297.1	lysine-arginine-ornithine-binding periplasmic protein precursor; LAO-binding protein (SW:ARGT_SALTY); ABC superfamily binding protein
NP_461298.1	with UbiD acts to catalyze the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate
NP_461304.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
NP_461305.1	membrane protein required for colicin V production
NP_461308.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
NP_461309.1	DedA family
NP_461310.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
NP_461312.1	catalyzes the formation of 3-hydroxy-4-phospho-hydroxy-alpha-ketobutyrate from erythronate-4-phosphate
NP_461313.1	in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein
NP_461320.1	FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
NP_461321.2	catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules
NP_461326.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
NP_461327.1	involved in methylation of ribosomal protein L3
NP_461328.1	contains Smr domain
NP_461331.1	FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth
NP_461336.1	outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA
NP_461337.1	phosphoglycerate transport system transcriptional regulatory protein PgtA (SW:PGTA_SALTY); phosphoglycerate transport
NP_461338.1	protein for signal transmission; PgtB (SW:PGTB_SALTY); phosphoglycerate transport
NP_461339.1	protein for signal transmission; PgtC (SW:PGTC_SALTY); phosphoglycerate transport
NP_461340.1	phosphoglycerate transporter protein (SW:PGTP_SALTY); phosphoglycerate transport
NP_461342.1	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock
NP_461344.1	catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate
NP_461349.1	manganese transport protein MntH (SW:MNTH_SALTY); Nramp family
NP_461351.1	diguanylate cyclase/phosphodiesterase domain 1; diguanylate cyclase/phosphodiesterase domain 2
NP_461354.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
NP_461362.1	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB
NP_461363.1	interacts with cell division protein FitsZ and may be required to anchor septal ring structure
NP_461364.1	role in sulfur assimilation
NP_461365.1	CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis
NP_461366.1	phosphocarrier protein HPR; histidine-containing protein (SW:PTHP_ECOLI); PTS family, Hpr protein
NP_461367.1	Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system
NP_461368.1	functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose
NP_461370.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal
NP_461371.1	transcriptional regulator PtsJ (SW:PTSJ_SALTY); GntR family
NP_461372.1	Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group
NP_461373.1	hypothetical 13.3 kDa protein in pdxK-cysM intergenic region (SW:YFEK_SALTY)
NP_461374.1	hypothetical 20.5 kDa protein in pdxK-cysM intergenic region
NP_461375.1	catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide
NP_461376.1	sulfate transport atp-binding protein CYSA (SW:CYSA_SALTY); ABC superfamily ATP-binding protein; chromate resistance
NP_461377.1	Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import
NP_461379.1	thiosulfate-binding protein (SW:CYSP_SALTY); ABC superfamily binding protein
NP_461385.1	probable N-acetylmuramoyl-L-alanine amidase AMIA (SW:AMIA_SALTY)
NP_461386.1	catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis
NP_461387.1	hypothetical protein in eutR-hemF intergenic region; ORF33 (SW:YPFK_SALTY)
NP_461388.1	hypothetical 30.0 kDa protein in eutR-hemF intergenic region (ORF79) (SW:YPFL_SALTY)
NP_461389.1	activates the transcription of the ethanolamine utilization operon
NP_461390.1	ethanolamine utilization protein EutK (SW:EUTK_SALTY)
NP_461391.1	ethanolamine utilization protein EutL (SW:EUTL_SALTY)
NP_461392.1	catalyzes the formation of acetaldehyde from ethanolamine
NP_461393.1	ethanolamine ammonia-lyase heavy chain (SW:EUTB_SALTY)
NP_461394.1	reactivating factor for ethanolamine ammonia lyase
NP_461395.1	ethanolamine utilization protein EutH (SW:EUTH_SALTY)
NP_461396.1	ethanolamine utilization protein EutG (SW:EUTG_SALTY)
NP_461398.1	invovled in ethanolamine utilization protein EutE (SW:EUTE_SALTY)
NP_461399.2	involved in ethanolamine utilization protein EutN (SW:EUTN_SALTY)
NP_461400.1	involved in ethanolamine utilization protein EutM (SW:EUTM_SALTY)
NP_461401.1	in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta
NP_461402.1	ethanolamine utilization cobalamin adenosyltransferase (SW:EUTT_SALTY)
NP_461403.1	ethanolamine utilization protein EutQ (SW:EUTQ_SALTY)
NP_461404.1	ethanolamine utilization protein EutP (SW:EUTP_SALTY)
NP_461405.1	ethanolamine utilization protein EutS (SW:EUTS_SALTY)
NP_461406.1	transposase for insertion sequence element IS200 (SW:T200_SALTY)
NP_461407.1	NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate
NP_461408.1	Maintains the balance of metabolites in the pentose-phosphate pathway
NP_461409.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
NP_461414.1	unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic)
NP_461418.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
NP_461422.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
NP_461424.1	catalyzes the formation of 4-hydroxy-tetrahydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
NP_461425.2	negative transcriptional regulator of the gcvTHP operon
NP_461426.1	bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine
NP_461429.1	inner membrane or exported protein
NP_461431.1	controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP
NP_461433.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
NP_461434.3	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
NP_461435.1	glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate
NP_461436.1	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate
NP_461445.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; converts ATP and xanthosine 5'-phosphate and L-glutamine and water to AMP and pyrophosphate diphosphate and GMP and L-glutamate
NP_461446.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
NP_461447.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
NP_461449.1	RatB
NP_461450.1	RatA
NP_461451.1	SinI
NP_461454.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
NP_461455.1	with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis
NP_461457.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
NP_461458.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
NP_461460.1	23S rRNA m2A2503 methyltransferase; tRNA m2A37 methyltransferase; methylates the C2 position of the A2530 and A37 nucleotides in 23S rRNA; may be involved in antibiotic resistance
NP_461461.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
NP_461466.1	penicillin-insensitive transglycosylase/transpeptidase
NP_461468.1	catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds
NP_461470.2	enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I
NP_461471.1	catalyzes the removal of an N-terminal amino acid from a peptide or arylamide
NP_461472.1	believed to be involved in assembly of Fe-S clusters
NP_461474.1	involved in the maturation of iron-sulfur cluster-containing proteins
NP_461475.1	J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins
NP_461476.1	iron-sulfur cluster assembly protein; forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein
NP_461478.1	catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis
NP_461479.1	regulates the expression of the iscRSUA operon
NP_461483.1	anaerobic sulfite reductase subunit A (anaerobic sulfite reductaseiron-sulfur subunit) (SW:ASRA_SALTY)
NP_461484.1	with AsrAC catalyzes the reduction of sulfite to hydrogen sulfide
NP_461485.1	anaerobic sulfite reductase subunit C (SW:ASRC_SALTY)
NP_461487.1	periplasmic protein
NP_461489.1	transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters
NP_461490.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
NP_461491.1	flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine
NP_461492.1	regulates the cadBA operon
NP_461493.1	antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein
NP_461494.1	lysine decarboxylase; inducible (SW:DCLY_SALTY)
NP_461496.1	indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA
NP_461500.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
NP_461502.1	member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents
NP_461506.1	catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway
NP_461507.1	ABC superfamily membrane protein
NP_461508.1	catalyzes the formation of 2-dehydropantoate from (R)-pantoate
NP_461512.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
NP_461513.1	involved in the de novo synthesis of pyridoxine (Vitamin B6)
NP_461514.1	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
NP_461515.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
NP_461516.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
NP_461517.1	catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins
NP_461518.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
NP_461519.1	leucine-rich repeat protein
NP_461522.1	phage tail assembly protein
NP_461523.1	phage tail assembly protein
NP_461560.1	acts to load the DnaB helicase onto the intiation site durning DNA replication
NP_461563.1	probable regulatory protein
NP_461572.1	involved in the reduction of the SoxR iron-sulfur cluster
NP_461573.1	periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP
NP_461575.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response
NP_461576.1	catalyzes the formation of oxaloacetate from L-aspartate
NP_461578.1	facilitates an early step in the assembly of the 50S subunit of the ribosome
NP_461581.1	stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit
NP_461582.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NP_461587.1	catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome
NP_461593.1	responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA
NP_461594.1	with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline
NP_461595.1	associated with 30S ribosomal subunit; interferes with translation elongation
NP_461597.1	catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis
NP_461599.1	catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis
NP_461600.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive
NP_461603.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NP_461604.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
NP_461605.1	Essential for efficient processing of 16S rRNA
NP_461606.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
NP_461607.1	with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins
NP_461611.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
NP_461613.1	catalyzes the phosphorylation of NAD to NADP
NP_461617.1	lipid transport protein
NP_461618.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
NP_461656.1	from prophage-like region
NP_461673.1	excinuclease
NP_461694.1	superfamily I
NP_461697.1	repressor of fliC (SW:FLJA_SALTY); flagellar synthesis
NP_461698.1	structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes
NP_461699.1	DNA-invertase hin (SW:HIN_SALTY); regulation of flagellar gene expression by site-specific H inversion of DNA
NP_461700.1	related to UDP-glucuronosyltransferase
NP_461703.1	alpha/beta superfamily
NP_461704.2	Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space
NP_461711.1	transcriptional regulatory protein TctD (SW:TCTD_SALTY); tricarboxylic transport
NP_461715.2	in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution
NP_461716.1	catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate
NP_461717.1	catalyzes the formation of succinate from succinate semialdehyde; NADP dependent
NP_461718.1	catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate
NP_461720.1	regulator of gab gene expression
NP_461721.1	LysM domain
NP_461722.1	YqaE family
NP_461723.1	ArsR family
NP_461725.1	DNA-binding protein STPA (SW:STPA_SALTY); has chaperone activity
NP_461731.1	glutaredoxin-like protein NrdH (SW:NRDH_SALTY); hydrogen donor
NP_461732.1	in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF
NP_461733.1	Catalyzes the rate-limiting step in dNTP synthesis
NP_461734.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
NP_461735.1	with ProWX is involved in the high-affinity uptake of glycine betaine
NP_461736.1	with ProVX is involved in the high-affinity uptake of glycine betaine
NP_461737.1	with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine
NP_461739.1	DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB
NP_461743.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
NP_461744.1	involved in the first step of glutathione biosynthesis
NP_461746.1	YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent
NP_461747.1	affects carbohydrate metabolism; has regulatory role in many processes
NP_461748.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_461749.1	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
NP_461750.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
NP_461752.1	membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan
NP_461755.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
NP_461756.1	catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate
NP_461757.1	regulator for glucitol utilization
NP_461758.1	regulates genes involved in glucitol utilization
NP_461759.2	catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate
NP_461760.1	Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon
NP_461761.1	detoxifies nitric oxide using NADH
NP_461762.1	catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase
NP_461764.1	involved in electron transport from formate to hydrogen
NP_461765.1	periplasmic protein
NP_461766.1	involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE
NP_461769.1	electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate
NP_461772.1	catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3)
NP_461774.1	regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon
NP_461775.1	plays a role in hydrogenase nickel cofactor insertion
NP_461776.1	GTP hydrolase involved in nickel liganding into hydrogenases
NP_461777.1	HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase
NP_461780.1	formate hydrogenlyase transcriptional activator for fdhF, hyc and hyp operons EBP family (SW:FHLA_SALTY)
NP_461782.1	SitA; Salmonella iron transporter; Fur-regulated
NP_461783.1	SitB; Salmonella iron transporter; Fur-regulated
NP_461784.1	SitC; Salmonella iron transporter; Fur-regulated
NP_461785.1	SitD; Salmonella iron transporter; Fur-regulated
NP_461786.1	invasion protein; inhbits activation of key proinflammatory transcription factor NF-kappaB
NP_461787.1	transcriptional regulator SprB
NP_461788.1	SprA; HilC; helix-turn-helix protein; AraC family; activator for invasion genes; derepresses hilA expression
NP_461790.1	oxygen-regulated invasion protein OrgB (SW:ORGB_SALTY); flagellar biosynthesis/type III secretion apparatus
NP_461791.1	oxygen-regulated invasion protein OrgA (SW:ORGA_SALTY); flagellar biosynthesis/type III secretion apparatus
NP_461792.1	needle complex inner membrane lipoprotein; cell invasion protein; interacts with PrgH and forms oligomeric rings; type III secretion apparatus
NP_461793.1	needle complex minor subunit; invasion protein; may cap needle complex; type III secretion apparatus
NP_461794.1	needle complex major subunit; invasion protein; type III secretion apparatus
NP_461795.1	needle complex inner membrane protein; invasion protein; interacts with PrgK; tetarmerizes; with PrgK forms multimeric ring-shaped structures; type III secretion apparatus
NP_461796.1	HilD; helix-turn-helix proteins; AraC family; activator for invasion genes; derepresses hilA expression
NP_461797.1	Activates the expression of invasion genes and activates the expression of prgHIJK which is part of the pathogenicity island 1 type III secretion system
NP_461798.1	invasion associated gene protein IagB (SW:IAGB_SALTY)
NP_461799.1	protein tyrosine phosphatase/GTPase activating protein; translocated protein; type III secretion; antagonizes bacterial-encoded exchange factors SopE and SopE2 by interfering with stimulation of Cdc42 and Rac1; binds Rac1
NP_461800.1	SicP; virulence protein; chaperone for SptP; type III secretion
NP_461802.1	carries the fatty acid chain in fatty acid biosynthesis
NP_461803.1	Salmonella invasion protein SipA; binds actin and promotes polymerization; results in membrane ruffling and internalization due to cytoskeleton rearrangements
NP_461804.1	cell invasion protein SspD protein; involved in translocating secreted proteins to host cells; translocon; type III secretion
NP_461805.1	cell invasion protein SspC; involved in translocating secreted proteins to host cell; translocon; type III secretion; inserted into host cell plasma membrane; interacts with SipC
NP_461806.1	cell invasion protein SspB, SipB; involved in translocating secreted proteins to host cell; translocon; type III secretion; inserted into host cell plasma membrane; interacts with SipC
NP_461807.1	surface presentation of antigens protein SpaT (SW:SPAT_SALTY); surface presentation of antigens; secretory proteins; partitioning factor for SipB/C; prevents premature association of SipB/C; regulates several promoters with InvF
NP_461808.1	Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins
NP_461809.1	needle complex export protein; inner membrane secretory protein; type III secretion apparatus
NP_461810.1	surface presentation of antigens protein SpaQ (SW:SPAQ_SALTY); inner membrane secretory protein; type III secretion apparatus
NP_461811.1	part of a type III secretory system probably involved in invasion into eukaryotic cells
NP_461812.1	involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells
NP_461813.1	surface presentation of antigens protein SpaN (SW:SPAN_SALTY); surface presentation of antigens; secretory proteins
NP_461814.1	surface presentation of antigens protein SpaM (SW:SPAM_SALTY); secretory proteins; type III secretion apparatus
NP_461815.1	Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase
NP_461816.1	surface presentation of antigens protein SpaK (SW:SPAK_SALTY); secretory protein; chaperone for SopE/SopE2; type III secretion
NP_461817.1	needle complex export protein; inner membrane protein; type III secretion apparatus
NP_461818.1	invasion protein InvE (SW:INVE_SALTY); interacts with SecA-SipB/C complex; essential for translocation into host cells
NP_461819.1	InvG protein (SW:INVG_SALTY); forms ring-shaped structure in outer membrane; requires InvH for stability; type III secretion apparatus
NP_461820.1	invasion protein InvF (SW:INVF_SALTY); SPI-1 transcription factor; activated by HilA; requires SicA as a co-factor; controls sigD/sopB, sopE and sicAsipBCDA genes
NP_461821.1	needle complex outer membrane lipoprotein; stabilizes InvG secretin; type III secretion apparatus
NP_461830.1	This protein performs the mismatch recognition step during the DNA repair process
NP_461845.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses
NP_461847.1	catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins
NP_461848.1	stationary phase survival protein SurE; catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
NP_461849.1	catalyzes the modification of U13 in tRNA(Glu)
NP_461850.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
NP_461851.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
NP_461852.1	forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein
NP_461854.1	converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis
NP_461855.1	may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ
NP_461856.1	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
NP_461857.1	catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3
NP_461866.1	hypothetical 36.1 kDa protein in cysH 3'region (ORF4) (SW:YGCC_SALTY); secreted by SPI-1; type III secretion
NP_461867.1	catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite
NP_461868.1	hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide
NP_461869.1	catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity
NP_461871.1	beta-lactamase superfamily II
NP_461872.1	organic radical activating enzymes
NP_461873.1	phosphopyruvate hydratase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
NP_461874.1	CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
NP_461875.1	functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era
NP_461876.2	contains CopG/Arc/MetJ DNA-binding domain and a metal-binding domain
NP_461877.1	(p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP
NP_461878.1	in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]
NP_461879.1	part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system
NP_461884.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NP_461885.1	catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp
NP_461887.1	SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function
NP_461888.1	catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis
NP_461892.2	has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups
NP_461894.1	catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate
NP_461895.1	catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose
NP_461898.1	regulates expression of genes involved in L-fucose utilization
NP_461901.1	Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence
NP_461907.1	membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues
NP_461909.1	catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis
NP_461910.1	helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity
NP_461911.1	helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity
NP_461913.1	catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination
NP_461918.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
NP_461919.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
NP_461920.1	member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr
NP_461921.1	hydrolyzes diadenosine polyphosphate
NP_461922.1	MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair
NP_461924.1	POT family
NP_461925.1	complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH
NP_461927.1	Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1
NP_461928.1	controls transcription of galETKM
NP_461930.1	catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding
NP_461931.1	activates the transcription of the lysA gene encoding diaminopimelate decarboxylase
NP_461934.1	catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate
NP_461935.1	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NP_461936.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis
NP_461941.1	membrane protein conferring nickel and cobalt resistance
NP_461949.1	transposase for insertion sequence element IS200 (SW:T200_SALTY)
NP_461950.1	toxin VapC; stability determinant protein
NP_461955.1	catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate
NP_461956.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
NP_461957.2	peptide chain release factor 2; RF-2 (SW:RF2_SALTY)
NP_461958.1	5'-3' single-stranded-DNA-specific exonuclease
NP_461959.1	DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity
NP_461960.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
NP_461961.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic
NP_461964.1	physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator
NP_461969.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine
NP_461970.1	part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
NP_461971.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
NP_461973.1	Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone
NP_461974.1	exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide
NP_461975.2	the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown
NP_461977.1	ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function
NP_461978.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
NP_461979.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
NP_461980.1	specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport
NP_461982.1	Involved in the export of arginine
NP_461983.1	participates in the regulation of osmotic pressure changes within the cel
NP_461984.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
NP_461985.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
NP_461986.1	NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate
NP_461989.1	CbiQ and related transporter
NP_461992.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
NP_461993.1	contains chaperone function
NP_461994.1	catalyzes the formation of putrescine from agmatine
NP_462002.1	catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis
NP_462006.1	methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
NP_462010.2	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
NP_462011.1	catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
NP_462016.1	enzyme with a TIM-barrel fold
NP_462019.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
NP_462022.1	catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis
NP_462025.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
NP_462028.1	Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues
NP_462036.1	transcriptional regulator; LysR family
NP_462045.1	inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS
NP_462050.1	catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate
NP_462052.1	catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism
NP_462054.1	catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction
NP_462055.1	YghU; B2989; one of eight glutathione transferase proteins from E. coli
NP_462059.1	plays a role in hydrogenase nickel cofactor insertion
NP_462061.1	protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC)
NP_462062.1	involved in hydrogen uptake
NP_462063.1	HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits
NP_462064.1	Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2
NP_462065.1	involved in hydrogen uptake
NP_462073.1	membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell
NP_462074.1	membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell
NP_462076.1	catalyzes the formation of L-homocysteine from cystathionine
NP_462079.1	similar to Escherichia coli oxidoreductase (AAC76047.1)
NP_462080.1	methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate
NP_462082.1	Ap4A
NP_462083.1	FeS oxidoreductase family 2
NP_462087.1	SufI protein (SW:SUFI_SALTY); periplasmic protein
NP_462088.1	1-acyl-SN-glycerol-3-phosphate acyltransferase (SW:PLSC_SALTY)
NP_462089.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
NP_462090.1	AraC family; helix-turn-helix
NP_462092.1	response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes
NP_462096.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
NP_462097.1	Displays esterase activity toward palmitoyl-CoA and pNP-butyrate
NP_462100.1	ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose
NP_462101.2	trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell
NP_462104.1	seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine
NP_462108.1	thiol-disulfide isomerase and thioredoxin
NP_462110.1	DHBP synthase; functions during riboflavin biosynthesis
NP_462112.1	Involved in glycogen synthesis. May be involved in glycogen priming
NP_462115.1	catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose
NP_462116.1	catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme
NP_462118.1	contains SH3 domain protein
NP_462119.1	catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases
NP_462120.2	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
NP_462121.2	catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin
NP_462122.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX
NP_462123.1	catalyzes the formation of a threonylcarbamoyl group at position 37 in tRNAs that read codons beginning with adenine
NP_462124.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
NP_462125.1	synthesizes RNA primers at the replication forks
NP_462126.2	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria
NP_462132.2	catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate
NP_462139.1	involved in the import of serine and threonine coupled with the import of sodium
NP_462140.1	DedA family
NP_462156.1	catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism
NP_462157.1	involved in the import of threonine and serine in combination with the import of a proton
NP_462158.1	catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic
NP_462159.1	regulates the tdcABCDEFG operon which is involved in amino acid degradation
NP_462161.1	catalyzes the reduction of tartronate semialdehyde to glycerate
NP_462162.1	cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate
NP_462166.1	catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
NP_462171.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
NP_462172.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
NP_462174.1	Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate
NP_462179.1	Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein
NP_462185.1	ABC superfamily membrane protein
NP_462192.1	tryptophan transporter of high affinity
NP_462193.2	participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division
NP_462194.1	lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing
NP_462196.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
NP_462197.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
NP_462198.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
NP_462199.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NP_462200.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
NP_462202.2	catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis
NP_462205.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NP_462206.1	catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate
NP_462207.1	inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins
NP_462208.1	Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit
NP_462209.2	RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability
NP_462210.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NP_462211.1	penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains
NP_462212.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
NP_462213.1	involved in the peptidyltransferase reaction during translation
NP_462216.1	activator of maltose metabolism genes
NP_462217.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
NP_462218.1	BolA family
NP_462219.1	STAS domain
NP_462220.1	ABC superfamily
NP_462221.1	ABC superfamily binding protein
NP_462222.1	ABC superfamily membrane protein
NP_462224.1	YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers
NP_462226.1	forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis
NP_462228.1	LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system
NP_462230.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen
NP_462231.1	sigma(54) modulation protein; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing
NP_462233.1	kinase; contains P-loop
NP_462236.1	glycosyltransferase; polymerizes glycan strands in the peptidoglycan
NP_462238.1	sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA
NP_462240.1	catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate
NP_462241.1	glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate
NP_462244.1	Catalyzes the deamination of cytosine to uracil and ammonia
NP_462246.1	catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein
NP_462247.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
NP_462249.1	catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid
NP_462250.1	Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization
NP_462252.1	transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation
NP_462254.1	forms a direct contact with the tRNA during translation
NP_462255.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
NP_462261.1	oxaloacetate decarboxylase beta chain (SW:DCOB_SALTY)
NP_462262.1	catalyzes the formation of pyruvate from oxaloacetate
NP_462263.1	catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide
NP_462264.1	Involved in the tartrate degradation pathway
NP_462265.1	Involved in the tartrate degradation pathway
NP_462267.1	GntR family
NP_462268.1	GntR family
NP_462269.1	oxidizes malate to oxaloacetate
NP_462270.1	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes
NP_462274.1	with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate
NP_462275.1	with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate
NP_462276.1	membrane protein AaeX; the gene is a member of the aaeXAB operon
NP_462278.1	responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA
NP_462280.1	involved in the processing of the 5'end of 16S rRNA
NP_462281.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
NP_462282.1	part of cell wall structural complex MreBCD; transmembrane component
NP_462283.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
NP_462284.1	functions in MreBCD complex in some organisms
NP_462285.1	regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules
NP_462287.1	in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ
NP_462288.1	in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme
NP_462289.1	composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NP_462290.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NP_462292.1	mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase
NP_462293.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
NP_462294.1	TIM-barrel enzyme; hypothetical 35.9 kDa protein in pmrA-fis intergenic region (SW:YHDG_SALTY)
NP_462295.1	Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription
NP_462298.1	membrane domain involved in; diguanylate cyclase/phosphodiesterase domain 1; diguanylate cyclase/phosphodiesterase domain 2
NP_462305.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
NP_462306.1	RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA
NP_462310.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
NP_462311.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
NP_462312.1	catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase
NP_462313.1	involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain
NP_462314.1	forms homopentamer; channel that opens in response to pressure or hypoosmotic shock
NP_462316.1	mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators
NP_462318.1	is a component of the macrolide binding site in the peptidyl transferase center
NP_462319.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
NP_462320.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
NP_462321.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
NP_462322.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
NP_462323.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
NP_462324.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
NP_462325.1	late assembly protein
NP_462326.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
NP_462327.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
NP_462328.1	binds 5S rRNA along with protein L5 and L25
NP_462329.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
NP_462330.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NP_462331.3	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
NP_462332.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
NP_462333.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
NP_462334.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
NP_462335.1	primary binding protein; helps mediate assembly; involved in translation fidelity
NP_462336.1	one of the stabilizing components for the large ribosomal subunit
NP_462337.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
NP_462338.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
NP_462339.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
NP_462340.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NP_462341.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
NP_462342.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
NP_462343.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
NP_462344.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
NP_462345.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
NP_462347.1	iron storage protein
NP_462348.1	regulatory or redox component complexing with Bfr in iron storage and mobility (SW:BFD_SALTY)
NP_462349.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
NP_462350.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
NP_462351.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
NP_462352.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
NP_462353.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
NP_462354.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
NP_462355.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
NP_462357.1	rotamase
NP_462359.1	rotamase
NP_462361.1	involved in potassium efflux
NP_462362.1	required for KefB activity
NP_462365.1	alpha/beta-hydrolase fold
NP_462369.1	complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons
NP_462371.1	DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate
NP_462372.1	aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity
NP_462373.1	cell filamentation protein Fic (SW:FIC_SALTY); stationary phase induced gene; affects cell division
NP_462374.1	hypothetical 6.8 kDa protein in fic-ppiA intergenic region (SW:YHFG_SALTY)
NP_462375.1	peptidyl-prolyl cis-trans isomerase A (SW:PPIA_SALTY); rotamase A
NP_462378.1	involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations
NP_462379.1	member of the FNT family of formate and nitrite transporters
NP_462380.1	multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin
NP_462382.1	transposase for insertion sequence element is200 (SW:T200_SALTY)
NP_462384.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_462385.1	catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate
NP_462386.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
NP_462387.1	DNA adenine methylase (SW:DMA_SALTY)
NP_462389.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
NP_462390.1	type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
NP_462391.1	outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa
NP_462396.2	bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits
NP_462397.2	ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose
NP_462400.1	predicted small RNA-binding protein
NP_462401.2	becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers
NP_462403.1	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
NP_462404.1	membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR
NP_462405.1	part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation
NP_462406.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NP_462409.1	cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake
NP_462412.1	Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis
NP_462416.1	amylomaltase; acts to release glucose from maltodextrins
NP_462418.1	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides
NP_462421.1	catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester
NP_462425.1	represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism
NP_462426.1	protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity
NP_462427.1	belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine
NP_462428.1	in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane
NP_462431.1	forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone
NP_462436.1	catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose
NP_462437.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
NP_462438.1	catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen
NP_462439.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
NP_462440.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
NP_462443.1	thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate
NP_462447.1	YhhY; regulated by the fur regulator; unknown function
NP_462448.2	regulator of sugar metabolism
NP_462452.1	periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides
NP_462454.1	hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate
NP_462455.1	part of the UgpABCE glycerol-3-phosphate uptake system
NP_462456.1	with UgpABC is involved in uptake of glycerol-3-phosphate
NP_462457.1	with UgpEC is involved in the uptake of glycerol-3-phosphate
NP_462458.1	with UgpACE is involved in the uptake of glycerol-3-phosphate
NP_462461.1	with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine
NP_462462.1	Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine
NP_462463.1	Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine
NP_462464.1	LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter
NP_462465.1	leucine-specific binding protein precursor; LS-BP (SW:LIVK_SALTY); ABC superfamily binding protein
NP_462468.1	leu/ile/val/thr-binding protein precursor; LIVT-BP (SW:LIVJ_SALTY); ABC superfamily binding protein
NP_462469.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
NP_462470.1	ABC transporter, membrane protein
NP_462471.1	ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions
NP_462472.1	signal recognition protein receptor; functions in the targeting and insertion of membrane proteins
NP_462473.1	catalyzes the methylation of 16S rRNA at position G966
NP_462477.1	P-type ATPase involved in the export of lead, cadmium, zinc and mercury
NP_462478.1	methyl-accepting chemotaxis citrate transducer (citrate chemoreceptorprotein) (SW:MCPC_SALTY)
NP_462479.1	TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs
NP_462483.1	PerM family
NP_462485.1	Inhibits transcription at high concentrations of nickel
NP_462491.1	ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress
NP_462493.1	member of the POT family of peptide transporters; probable proton-dependent peptide transporter function
NP_462494.1	predicted SAM-dependent methyltransferase
NP_462495.1	oligopeptidase A (SW:OPDA_SALTY)
NP_462498.1	catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense
NP_462504.1	cytoplasmic; catalyzes the hydrolysis of trehalose to glucose
NP_462512.1	in Escherichia coli this protein is involved in flagellar function
NP_462514.1	protein YhjJ (SW:YHJJ_SALTY)
NP_462515.1	involved in the transport of C4-dicarboxylates across the membrane
NP_462516.2	HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli
NP_462517.1	cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA
NP_462518.1	catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans
NP_462519.1	binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP)
NP_462520.1	polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis
NP_462528.1	Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides
NP_462529.1	DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF
NP_462531.1	transports peptides consisting of two or three amino acids
NP_462534.1	contains PQQ enzyme repeat
NP_462536.1	catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide
NP_462538.1	LpfD protein (SW:LPFD_SALTY)
NP_462539.1	outer membrane usher protein LpfC (SW:LPFC_SALTY)
NP_462540.1	chaperone protein LpfB (SW:LPFB_SALTY)
NP_462541.1	long polar fimbrial protein A (SW:LPFA_SALTY)
NP_462543.1	constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine
NP_462547.1	Involved in the metabolism of aromatic amino acids
NP_462550.1	cold shock protein CspA (SW:CSPA_SALTY); 7.4 kDa; transcriptional activator of hns
NP_462555.1	glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
NP_462556.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
NP_462561.1	catalyzes the interconversion of D-xylose to D-xylulose
NP_462564.1	periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds
NP_462565.1	transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis
NP_462568.1	NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate
NP_462571.1	membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO
NP_462575.1	catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate
NP_462576.1	L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate
NP_462577.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NP_462583.1	catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis
NP_462587.1	Acts as a repressor of the mtlAD operon
NP_462593.1	represses the lctPRD operon
NP_462594.1	flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration
NP_462595.1	member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates
NP_462599.1	catalyzes the O-acetylation of serine
NP_462600.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
NP_462601.1	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA
NP_462604.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NP_462608.1	converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism
NP_462609.1	catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine
NP_462610.1	catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose
NP_462611.1	catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core
NP_462612.1	lipopolysaccharide heptosyltransferase-1 (SW:RFAC_SALTY)
NP_462613.1	O-antigen ligase (SW:RFAL_SALTY)
NP_462614.1	lipopolysaccharide 1,2-N-acetylglucosaminetransferase (SW:RFAK_SALTY); lipopolysaccharide core biosynthetic protein
NP_462615.1	lipopolysaccharide core biosynthetic protein RfaZ (SW:RFAZ_SALTY)
NP_462616.1	lipopolysaccharide core biosynthesis protein RfaY (SW:RFAY_SALTY); modification of heptose region of the core
NP_462617.1	UDP-D-glucose/galactosyl; lipopolysaccharide 1,2-glucosyltransferase (SW:RFAJ_SALTY)
NP_462618.1	UDP-D-galactose/glucosyl; lipopolysaccharide 1,3-galactosyltransferase (SW:RFAI_SALTY)
NP_462619.1	UDP-D-galactose/(glucosyl; lipopolysaccharide 1,6-galactosyltransferase (SW:RFAB_SALTY)
NP_462620.1	hypothetical 9.0 kDa protein in rfaB-rfaP intergenic region (SW:YIBR_SALTY)
NP_462621.1	lipopolysaccharide core biosynthetic protein RfaP (SW:RFAP_SALTY); phosphorylation of core heptose
NP_462624.1	catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A
NP_462625.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
NP_462626.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
NP_462627.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
NP_462628.1	required for 70S ribosome assembly
NP_462630.2	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
NP_462631.1	catalyzes the formation of dUMP from dUTP
NP_462632.1	FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly
NP_462633.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
NP_462634.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
NP_462639.1	this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+
NP_462640.1	Essential for recycling GMP and indirectly, cGMP
NP_462641.1	promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NP_462643.1	specifically modifies tRNA at position G18
NP_462644.1	catalyzes branch migration in Holliday junction intermediates
NP_462649.1	catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides
NP_462650.1	may be involved in the transport of galactosides-pentoses-hexuronides
NP_462654.1	RhuM
NP_462655.1	RmbA
NP_462657.1	FidL
NP_462661.1	CigR
NP_462662.1	Mg(2+) transport ATPase, P-type 2 (SW:ATMB_SALTY); cotranscribed with mgtC
NP_462663.1	Mg(2+) transport ATPase protein C (SW:ATMC_SALTY); reqired for intracmacrophage survival and growth in low calcium; cotranscribed with mgtB and transcriptionally controlled by PhoP/PhoQ system
NP_462667.1	L-seryl-tRNA selenium transferase
NP_462675.1	experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS
NP_462677.1	helix-turn-helix
NP_462679.1	class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis
NP_462686.1	cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate
NP_462687.1	membrane protein regulates uhpT expression
NP_462688.1	Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph
NP_462689.1	response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter
NP_462694.1	with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit
NP_462695.1	catalyzes the formation of 2-acetolactate from pyruvate
NP_462699.1	multidrug efflux protein involved in adaptation to low energy shock
NP_462701.1	regulates the synthesis and expression of the dsdXA operon and dadA gene
NP_462702.1	member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function
NP_462703.1	catalyzes the formation of pyruvate from serine
NP_462708.3	16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent
NP_462709.3	with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress
NP_462713.1	Thiol:disulfide interchange protein DsbE
NP_462719.1	ATP-binding protein; required for proper cytochrome c maturation
NP_462721.1	TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor
NP_462724.1	response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes
NP_462725.1	periplasmic sensory protein associated with the TorRS two-component regulatory system
NP_462726.1	Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide
NP_462731.1	YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins
NP_462735.1	negatively supercoils closed circular double-stranded DNA
NP_462736.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
NP_462737.1	binds the polymerase to DNA and acts as a sliding clamp
NP_462738.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
NP_462739.1	in Escherichia coli transcription of this gene is enhanced by polyamines
NP_462740.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
NP_462742.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
NP_462743.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
NP_462745.2	RNA-dependent DNA polymerase
NP_462746.1	Confers resistance to chloramphenicol
NP_462747.1	Involved in anaerobic NO protection
NP_462751.1	YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily
NP_462752.1	regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon
NP_462753.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
NP_462754.1	Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions
NP_462755.1	part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions
NP_462758.1	catalyzes the conversion of shikimate to 3-dehydroshikimate
NP_462760.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NP_462761.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
NP_462763.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
NP_462764.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
NP_462765.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
NP_462766.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
NP_462767.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
NP_462768.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
NP_462769.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
NP_462770.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
NP_462771.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
NP_462772.3	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
NP_462773.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
NP_462774.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NP_462775.1	transcriptional repressor of asnA which codes for aspartate-ammonia ligase
NP_462776.1	catalyzes the formation of asparagine from aspartate and ammonia
NP_462777.2	contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA
NP_462778.1	interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase
NP_462779.1	Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH
NP_462780.1	cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source
NP_462781.1	with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain
NP_462782.1	functions to transport ribose at high affinity; forms a complex with RbsA2C2B
NP_462783.1	periplasmic substrate-binding component of the ATP-dependent ribose transport system
NP_462784.1	catalyzes the formation of D-ribose 5-phosphate from ribose
NP_462785.1	DNA-binding transcriptional repressor of ribose metabolism
NP_462787.1	GntR family
NP_462788.2	Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon
NP_462789.1	LysR type regulator; with pssR
NP_462790.1	among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function
NP_462791.1	ilvGmedA operon leader peptide; attenuator peptide (SW:LPID_ECOLI)
NP_462792.1	catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit
NP_462794.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
NP_462795.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
NP_462796.1	threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway
NP_462799.1	participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate
NP_462800.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
NP_462803.1	single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication
NP_462804.1	catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation
NP_462805.1	enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation
NP_462806.1	thioredoxin 1; TRX1; TRX (SW:THIO_ECOLI); redox factor
NP_462807.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
NP_462809.1	Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein
NP_462811.1	catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid
NP_462815.1	catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis
NP_462817.1	catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis
NP_462818.1	enterobacterial common antigen polymerase
NP_462819.1	probable UDP-N-acetyl-D-mannosaminuronic acid transferase (SW:WECG_SALTY)
NP_462820.1	uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function
NP_462823.1	catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis
NP_462824.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
NP_462825.1	catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP
NP_462829.1	defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly
NP_462832.2	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
NP_462833.1	hypothetical protein in dapF-xerC intergenic region (SW:YIGA_SALTY)
NP_462834.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
NP_462835.1	YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function
NP_462836.1	unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.
NP_462837.1	responsible for the influx of magnesium ions
NP_462838.1	hypothetical 14.6 kDa protein in corA-rarD intergenic region (SW:YIGF_SALTY)
NP_462841.2	hypothetical protein in rarD-pldA intergenic region (SW:YIGI_SALTY); possibly involved in aromatic compounds catabolism; PaaI
NP_462842.1	catalyzes the hydrolysis of phosphatidylcholine
NP_462843.1	functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway
NP_462844.1	RhtB family
NP_462846.1	lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates
NP_462847.1	purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium
NP_462849.1	transcriptional activator protein metR (SW:METR_SALTY); LysR family
NP_462850.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
NP_462853.1	catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway
NP_462854.1	YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner
NP_462855.1	Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; converts 2-octaprenyl-6-methoxy-1,4-benzoquinone to 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone
NP_462857.1	an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions
NP_462858.1	TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes
NP_462859.1	mediates the export of protein precursors bearing twin-arginine signal peptides
NP_462860.1	with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane
NP_462861.3	magnesium dependent; not involved in the Sec-independent protein export system
NP_462863.1	catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol
NP_462864.1	NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin
NP_462867.1	FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids
NP_462868.1	includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids
NP_462869.1	catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters
NP_462872.1	catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX
NP_462873.1	in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway
NP_462874.1	in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis
NP_462876.1	serine/threonine protein kinase; MazF antagonist; catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages
NP_462877.1	thiol-disulfide interchange protein DabA (SW:DSBA_SALTY)
NP_462879.1	has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair
NP_462881.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
NP_462884.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
NP_462885.1	response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54
NP_462886.1	sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation
NP_462887.1	forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme
NP_462890.1	similar to Escherichia coli phosphatase (AAC73853.1)
NP_462892.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
NP_462896.1	porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown
NP_462908.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
NP_462913.2	merR family
NP_462914.1	required for the formation of active formate dehydrogenase
NP_462915.1	cytochrome b556(FDO) component; heme containing
NP_462918.1	involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth
NP_462927.1	catalyzes the formation of L-rhamnulose from L-rhamnose
NP_462928.1	catalyzes the ATP-dependent phosphorylation of rhamnulose
NP_462929.1	activates the expression of the rhaBAD operon and rhaT gene
NP_462930.1	activates the expression of rhaRS in response to L-rhamnose
NP_462931.1	transports L-rhamnose and L-lyxose into the cell
NP_462932.2	hypothetical 15.6 kDa protein in RhaT 5'region (SW:YIIY_SALTY)
NP_462935.1	hypothetical protein in sodA 5'region (SW:YIIZ_SALTY)
NP_462936.1	SodA; manganese binding; only present under aerobic conditions; destroys free radicals
NP_462939.1	part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors
NP_462940.1	response regulator in two-component regulatory system with CpxA; part of the envelope stress response system
NP_462941.1	repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates
NP_462942.1	member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers
NP_462943.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
NP_462944.1	sulfate-binding protein (SW:SUBI_SALTY); ABC superfamily binding protein
NP_462945.1	CDP-diacylglycerol pyrophosphatase (SW:CDH_SALTY)
NP_462947.1	phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least
NP_462961.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
NP_462962.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
NP_462966.1	type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese
NP_462967.1	Converts glycerol and ADP to glycerol-3-phosphate and ADP
NP_462970.1	regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity
NP_462971.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
NP_462972.1	heat shock protein involved in degradation of misfolded proteins
NP_462973.1	heat shock protein involved in degradation of misfolded proteins
NP_462975.1	negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins
NP_462976.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
NP_462977.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
NP_462980.1	when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis
NP_462981.1	catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine
NP_462982.1	multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways
NP_462986.1	MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor
NP_462987.1	peroxidase/catalase HPI (SW:CATA_SALTY)
NP_462989.1	forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone
NP_462992.1	FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site
NP_462993.1	FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS
NP_462994.1	involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein
NP_462996.1	FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog
NP_462999.1	catalyzes the formation of oxaloacetate from phosphoenolpyruvate
NP_463000.1	catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis
NP_463001.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
NP_463002.2	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
NP_463003.1	catalyzes the formation of arginine from (N-L-arginino)succinate
NP_463004.1	Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA
NP_463005.1	catalyzes the conversion of NADPH to NADH
NP_463006.2	negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis
NP_463008.1	catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs
NP_463009.1	involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space
NP_463010.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
NP_463011.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
NP_463012.1	catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon
NP_463013.1	catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis
NP_463015.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
NP_463016.1	forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
NP_463017.1	Modulates Rho-dependent transcription termination
NP_463018.1	binds directly to 23S ribosomal RNA
NP_463019.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
NP_463020.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
NP_463021.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
NP_463022.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
NP_463023.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
NP_463028.1	in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; catalyzes the formation of 2-iminoacetate and 4-cresol from tyrosine; forms a complex with ThiG; contains an iron-sulfur center
NP_463029.1	functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate
NP_463030.1	with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate
NP_463031.1	catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate
NP_463032.1	catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate
NP_463033.1	required for the synthesis of the hydromethylpyrimidine moiety of thiamine
NP_463034.1	binds specifically to the major sigma factor sigma 70; active in stationary phase
NP_463035.1	can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates
NP_463036.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
NP_463037.1	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures
NP_463039.1	histone-like DNA-binding protein
NP_463042.1	sensor protein HydA (SW:HYDH_SALTY); in two component regulatory system with HydG
NP_463043.1	DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein
NP_463044.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
NP_463045.1	involved in de novo purine biosynthesis
NP_463047.1	catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis
NP_463048.1	Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle
NP_463049.1	Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates
NP_463050.1	catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol
NP_463052.1	regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase
NP_463053.2	one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity
NP_463055.1	alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family
NP_463058.1	catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA
NP_463085.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive
NP_463086.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
NP_463092.1	with MalKFE is involved in the transport of maltose into the cell
NP_463093.1	with MalKGE is involved in maltose transport into the cell
NP_463094.2	functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis
NP_463095.1	with malEFG is involved in import of maltose/maltodextrin
NP_463096.1	porin involved in the transport of maltose and maltodextrins
NP_463097.1	maltose operon periplasmic protein (SW:MALM_SALTY); protein of mal regulon
NP_463098.1	catalyzes the formation of 4-hydroxybenzoate from chorismate
NP_463099.1	catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway
NP_463100.1	PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA
NP_463102.1	Represses a number of genes involved in the response to DNA damage
NP_463105.1	unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential
NP_463106.1	Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB
NP_463108.1	TIM-barrel enzyme; possibly dehydrogenases; nifR3 family
NP_463109.1	coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia
NP_463111.1	unwinds double stranded DNA
NP_463112.1	converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer
NP_463113.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
NP_463114.1	Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity
NP_463119.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NP_463121.1	binds to single stranded DNA and PriA helcase facilitate replication restart
NP_463122.1	inner membrane or exported protein spi4_A
NP_463125.1	membrane permease; HlyD secretion protein
NP_463126.1	fusion of two Salmonella typhimurium hypothetical proteins; may contain rearrangements with respect to similar proteins
NP_463130.1	regulates genes involved in response to oxidative stress
NP_463131.1	redox-sensitive transcriptional activator SOXR (SW:SOXR_SALTY); MerR family; contains iron-sulfur center for redox-sensing
NP_463133.1	xanthine/uracil permease family
NP_463134.1	CPA1 family
NP_463138.1	member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake
NP_463140.1	Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA
NP_463142.1	catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552
NP_463143.2	part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia
NP_463148.1	carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system
NP_463149.1	contains TPR repeats
NP_463151.1	dioxygenase for lipid synthesis; LpxO
NP_463152.2	PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role
NP_463154.1	involved in phosphonate metabolism
NP_463156.1	sensor protein BasS/PmrB (SW:BASS_SALTY); in two-component regulatory system with BasR
NP_463157.1	response regulator in two-component regulatory system with BasS
NP_463158.1	involved in resistance to polymixin B by modifying lipid A
NP_463163.1	alpha-galactosidase (SW:AGAL_SALTY)
NP_463164.1	melibiose carrier protein; thiomethylgalactoside permease; melibiose permease; Na+/Li+ melibiose symporter; melibiosetransporter (SW:MELB_SALTY); GPH family
NP_463166.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters
NP_463168.1	response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration
NP_463169.1	C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration
NP_463176.1	transposase for insertion sequence element is200 (SW:T200_SALTY)
NP_463179.2	LuxR family
NP_463180.1	HilD; AraC-type; contains DNA-binding domain
NP_463182.1	CopG family; helix-turn-helix protein
NP_463184.1	nonspecific acid phosphatase (SW:PHON_SALTY)
NP_463187.1	two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm
NP_463188.1	copper binding protein required for copper tolerance; involved in resistance toward heavy metals
NP_463189.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB
NP_463190.1	catalyzes the formation of fumarate from aspartate
NP_463191.2	F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein
NP_463192.1	uncharacterized member of the APC superfamily of amino acid transporters; unknown function
NP_463193.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
NP_463194.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
NP_463198.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
NP_463201.1	LuxR family
NP_463202.1	member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations
NP_463203.1	lipocalin; globomycin-sensitive outer membrane lipoprotein
NP_463204.1	in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane
NP_463205.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
NP_463206.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
NP_463207.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
NP_463208.1	catalyzes the activation of beta-lysine which is then transfered to L34 of EF-P
NP_463209.1	hypothetical protein in poxA-psd intergenic region (SW:YJEM_SALTY); APC family
NP_463212.1	catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine
NP_463213.2	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
NP_463214.1	3'-5' exoribonuclease specific for small oligoribonuclotides
NP_463219.1	N-acetylmuramoyl-L-alanine amidase AMIB (SW:AMIB_SALTY); a murein hydrolase
NP_463220.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NP_463221.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
NP_463222.1	Stimulates the elongation of poly(A) tails
NP_463223.1	involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein
NP_463224.1	with HflC inhibits proteolysis of lambda cII protein by FtsH
NP_463225.1	with HflK inhibits proteolysis of lambda cII protein by FtsH
NP_463227.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
NP_463228.1	negatively regulates the transcription of genes upregulated by nitrosative stress
NP_463229.1	3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs
NP_463230.1	Specifically methylates the ribose of guanosine 2251 in 23S rRNA
NP_463240.1	in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility
NP_463241.1	YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo
NP_463242.1	negative regulator of ulaG and ulaABCDEF
NP_463243.1	contains beta-lactamase fold
NP_463244.2	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
NP_463245.1	involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
NP_463246.1	involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
NP_463247.1	catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization
NP_463248.1	UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway
NP_463249.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NP_463252.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
NP_463253.1	binds single-stranded DNA at the primosome assembly site
NP_463254.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
NP_463255.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
NP_463258.2	FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NP_463259.1	involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine
NP_463260.1	Involved in anaerobic NO protection and iron metabolism
NP_463264.1	periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate
NP_463265.1	catalyzes the formation of AMP from adenosine-3',5'-bisphosphate
NP_463269.1	this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
NP_463274.1	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides
NP_463275.1	catalyzes the hydrolysis of pyrophosphate to phosphate
NP_463276.1	catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate
NP_463299.1	protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD
NP_463301.1	nitrogen regulation protein NR(ii) (SW:NTRB_SALTY)
NP_463306.1	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides
NP_463307.1	L-seryl-tRNA selenium transferase
NP_463309.1	Ntr-type
NP_463310.1	Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor
NP_463312.1	activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions
NP_463313.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
NP_463315.1	regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon
NP_463316.1	P-type ATPase involved in magnesium influx
NP_463319.1	involved in the allosteric regulation of aspartate carbamoyltransferase
NP_463320.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
NP_463321.1	pyrBI operon leader peptide (attenuator) (SW:LPPY_SALTY); contains a frameshift and premature stop as compared to Escherichia coli pyrBI operon leader peptide
NP_463325.1	catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway
NP_463326.1	reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
NP_463327.1	catalyzes the degradation of arginine to citruline and ammonia
NP_463329.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.
NP_463330.1	hypothetical 15.7 dda protein in argI-miaE intergenic region (ORF15.6) (SW:YJGD_SALTY)
NP_463331.1	tRNA-hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA (SW:MIAE_SALTY)
NP_463332.1	hypothetical 17.8 kKa protein in miaE 3'region (ORF 17.8) (SW:YTGA_SALTY)
NP_463333.1	hypothetical 18.3 kDa protein in miaE 3'region (ORF 18.3) (SW:YJGM_SALTY)
NP_463334.1	hypothetical protein in miaE 3'region (ORF x) (SW:YJGN_SALTY)
NP_463335.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
NP_463336.2	binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
NP_463337.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
NP_463343.1	Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate
NP_463344.1	NAD-binding
NP_463349.1	Mrr
NP_463363.1	IicA
NP_463364.1	inner membrane or exported
NP_463366.1	regulates the expression of uxuBA
NP_463367.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_463382.1	involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response
NP_463383.1	S protein; STYSJI specificity protein (SW:T1S_SALTY); specificity determinant for hsdM and hsdR
NP_463384.1	type I restriction enzyme STYSJI Mm protein (SW:T1M_SALTY); host modification
NP_463385.1	restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities
NP_463400.2	catalyzes the transfer of phosphoglycerol to the glucan backbone
NP_463402.1	acts to load the DnaB helicase onto the initiation site during DNA replication
NP_463403.1	This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'
NP_463407.2	regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin
NP_463409.1	involved in reduction of ferric iron in cytoplasmic ferrioxamine B
NP_463410.1	contains diguanylate cyclase/phosphodiesterase domain 1
NP_463412.1	16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit
NP_463413.1	with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
NP_463414.1	alanine acetyltransferase that specifically acetylates ribosomal protein S18
NP_463415.2	manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily
NP_463416.1	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein
NP_463423.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
NP_463424.1	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NP_463425.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
NP_463426.1	catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate
NP_463429.1	member of the periplasmic pilus chaperone family of proteins
NP_463432.1	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins
NP_463433.1	membrane protein; transcribed divergently from serB
NP_463434.1	catalyzes the formation of serine from O-phosphoserine
NP_463435.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
NP_463436.4	catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; also has a regulatory function
NP_463437.1	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence
NP_463438.2	catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan
NP_463439.1	When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription
NP_463440.1	pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog
NP_463441.1	catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate
NP_463444.1	response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation
NP_463445.1	part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation
NP_463456.1	member of the SPOUT superfamily of methyltransferases
NP_490497.1	acts to regulate the expression of the plasmid replication protein RepA in the IncFII plasmid group
NP_490498.2	RepA
NP_490500.1	sdiA-regulated gene; putative bacterial helix-turn-helix proteins; member of araC family; rcK
NP_490501.1	srgB
NP_490502.1	sdiA-regulated gene; srgA
NP_490503.1	sdiA-regulated gene; orf7
NP_490504.1	luxR family; pefI
NP_490505.1	plasmid-encoded fimbriae; orf6
NP_490506.1	orf5
NP_490507.1	pefD
NP_490508.1	plasmid-encoded fimbriae; pefC
NP_490509.1	plasmid-encoded fimbriae; pefA
NP_490510.1	plasmid-encoded fimbriae; pefB
NP_490511.1	plasmid-encoded fimbriae
NP_490517.1	toxin addiction system
NP_490518.1	controlled cell death protein; post-segregation toxin; toxin addiction system
NP_861530.1	similar to orf from Salmonella enteritidis virulence plasmid
NP_490526.1	IS200-like
NP_490527.1	Salmonella typhimurium plasmid virulence protein
NP_490528.1	Salmonella typhimurium plasmid virulence protein
NP_490529.1	Salmonella typhimurium plasmid virulence protein
NP_490530.1	Salmonella typhimurium plasmid virulence protein; spvR
NP_490531.1	Salmonella typhimurium plasmid virulence protein; lysR family
NP_490533.1	similar to ExeA protein
NP_861531.1	similar to orf40 from Salmonella enteritidis virulence plasmid
NP_490544.1	binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization
NP_490545.1	protection from mutagenesis by UV and mutagens; similar to umuDC operon
NP_490553.1	similar to DNA polymerase III theta subunit
NP_490557.1	plasmid SOS inhibition
NP_490558.1	PsiA
NP_490560.1	conjugative transfer; DNA-binding protein
NP_490561.1	conjugative transfer; positively regulates transfer operon transcription; negatively regulated by finP; positively regulated by Lrp
NP_490562.1	conjugative transfer; promotes nicking at oriT and transfer operon transcription
NP_490563.1	conjugative transfer; pilin
NP_490564.1	conjugative transfer
NP_490565.1	conjugative transfer
NP_490566.1	conjugative transfer
NP_490567.1	conjugative transfer
NP_490570.1	conjugative transfer; putative outer membrane lipoprotein
NP_490572.1	conjugative transfer
NP_490573.1	similar to VirB4
NP_490574.1	conjugative transfer
NP_490575.1	conjugative transfer
NP_490576.1	conjugative transfer
NP_490577.1	conjugative transfer
NP_490578.1	conjugative transfer
NP_490579.1	TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell
NP_490581.1	type IV secretion system pilus assembly protein; similar to F plasmid TraF
NP_490582.1	conjugative transfer
NP_490584.1	conjugative transfer
NP_490585.1	conjugative transfer
NP_490586.1	conjugative transfer
NP_490587.1	conjugative transfer
NP_490588.1	type IV secretion system coupling protein; similar to F plasmid TraD
NP_490590.1	stability determinant protein
NP_490592.1	cleaves origin of transfer and unwinds; oriT relaxase
NP_490593.1	conjugative transfer
NP_490594.1	conjugative transfer; srgC