-- dump date   	20140620_055600
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1171376000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1171376000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1171376000003	putative catalytic residues [active]
1171376000004	putative nucleotide binding site [chemical binding]; other site
1171376000005	putative aspartate binding site [chemical binding]; other site
1171376000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1171376000007	dimer interface [polypeptide binding]; other site
1171376000008	putative threonine allosteric regulatory site; other site
1171376000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1171376000010	putative threonine allosteric regulatory site; other site
1171376000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1171376000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1171376000013	homoserine kinase; Provisional; Region: PRK01212
1171376000014	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1171376000015	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1171376000016	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1171376000017	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376000018	catalytic residue [active]
1171376000019	hypothetical protein; Validated; Region: PRK02101
1171376000020	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1171376000021	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1171376000022	transaldolase-like protein; Provisional; Region: PTZ00411
1171376000023	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1171376000024	active site
1171376000025	dimer interface [polypeptide binding]; other site
1171376000026	catalytic residue [active]
1171376000027	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1171376000028	MPT binding site; other site
1171376000029	trimer interface [polypeptide binding]; other site
1171376000030	hypothetical protein; Provisional; Region: PRK10659
1171376000031	hypothetical protein; Provisional; Region: PRK10236
1171376000032	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1171376000033	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1171376000034	Protein of unknown function (DUF2541); Region: DUF2541; pfam10807
1171376000035	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1171376000036	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1171376000037	nucleotide binding site [chemical binding]; other site
1171376000038	chaperone protein DnaJ; Provisional; Region: PRK10767
1171376000039	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1171376000040	HSP70 interaction site [polypeptide binding]; other site
1171376000041	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1171376000042	substrate binding site [polypeptide binding]; other site
1171376000043	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1171376000044	Zn binding sites [ion binding]; other site
1171376000045	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1171376000046	dimer interface [polypeptide binding]; other site
1171376000047	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376000048	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376000049	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376000050	dimerization interface [polypeptide binding]; other site
1171376000051	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1171376000052	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1171376000053	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1171376000054	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1171376000055	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
1171376000056	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1171376000057	active site
1171376000058	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1171376000059	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1171376000060	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1171376000061	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1171376000062	Helix-turn-helix domain; Region: HTH_36; pfam13730
1171376000063	fimbrial protein BcfA; Provisional; Region: PRK15187
1171376000064	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
1171376000065	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376000066	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376000067	outer membrane usher protein; Provisional; Region: PRK15193
1171376000068	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376000069	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376000070	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376000071	fimbrial protein BcfD; Provisional; Region: PRK15189
1171376000072	fimbrial protein BcfE; Provisional; Region: PRK15190
1171376000073	fimbrial protein BcfF; Provisional; Region: PRK15191
1171376000074	fimbrial chaperone BcfG; Provisional; Region: PRK15192
1171376000075	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376000076	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376000077	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1171376000078	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1171376000079	catalytic residues [active]
1171376000080	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1171376000081	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376000082	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376000083	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376000084	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1171376000085	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1171376000086	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1171376000087	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1171376000088	active site
1171376000089	metal binding site [ion binding]; metal-binding site
1171376000090	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1171376000091	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
1171376000092	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1171376000093	Sulfatase; Region: Sulfatase; pfam00884
1171376000094	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1171376000095	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376000096	FeS/SAM binding site; other site
1171376000097	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1171376000098	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1171376000099	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1171376000100	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1171376000101	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1171376000102	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376000103	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1171376000104	putative dimerization interface [polypeptide binding]; other site
1171376000105	putative alpha-glucosidase; Provisional; Region: PRK10658
1171376000106	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1171376000107	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
1171376000108	putative active site [active]
1171376000109	putative catalytic site [active]
1171376000110	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1171376000111	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1171376000112	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1171376000113	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
1171376000114	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1171376000115	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1171376000116	active site
1171376000117	Riboflavin kinase; Region: Flavokinase; smart00904
1171376000118	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1171376000119	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1171376000120	active site
1171376000121	HIGH motif; other site
1171376000122	nucleotide binding site [chemical binding]; other site
1171376000123	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1171376000124	active site
1171376000125	KMSKS motif; other site
1171376000126	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1171376000127	tRNA binding surface [nucleotide binding]; other site
1171376000128	anticodon binding site; other site
1171376000129	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1171376000130	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1171376000131	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1171376000132	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1171376000133	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1171376000134	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1171376000135	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1171376000136	active site
1171376000137	tetramer interface [polypeptide binding]; other site
1171376000138	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1171376000139	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376000140	active site
1171376000141	phosphorylation site [posttranslational modification]
1171376000142	intermolecular recognition site; other site
1171376000143	dimerization interface [polypeptide binding]; other site
1171376000144	Transcriptional regulator; Region: CitT; pfam12431
1171376000145	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1171376000146	PAS domain; Region: PAS; smart00091
1171376000147	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376000148	ATP binding site [chemical binding]; other site
1171376000149	Mg2+ binding site [ion binding]; other site
1171376000150	G-X-G motif; other site
1171376000151	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1171376000152	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1171376000153	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1171376000154	active site
1171376000155	catalytic residues [active]
1171376000156	metal binding site [ion binding]; metal-binding site
1171376000157	homodimer binding site [polypeptide binding]; other site
1171376000158	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1171376000159	carboxyltransferase (CT) interaction site; other site
1171376000160	biotinylation site [posttranslational modification]; other site
1171376000161	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1171376000162	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
1171376000163	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1171376000164	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1171376000165	putative active site [active]
1171376000166	(T/H)XGH motif; other site
1171376000167	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1171376000168	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1171376000169	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1171376000170	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1171376000171	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1171376000172	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
1171376000173	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1171376000174	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1171376000175	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1171376000176	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1171376000177	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1171376000178	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1171376000179	catalytic site [active]
1171376000180	subunit interface [polypeptide binding]; other site
1171376000181	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1171376000182	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1171376000183	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1171376000184	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1171376000185	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1171376000186	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1171376000187	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1171376000188	IMP binding site; other site
1171376000189	dimer interface [polypeptide binding]; other site
1171376000190	interdomain contacts; other site
1171376000191	partial ornithine binding site; other site
1171376000192	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
1171376000193	carnitine operon protein CaiE; Provisional; Region: PRK13627
1171376000194	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1171376000195	putative trimer interface [polypeptide binding]; other site
1171376000196	putative metal binding site [ion binding]; other site
1171376000197	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
1171376000198	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1171376000199	substrate binding site [chemical binding]; other site
1171376000200	oxyanion hole (OAH) forming residues; other site
1171376000201	trimer interface [polypeptide binding]; other site
1171376000202	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
1171376000203	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
1171376000204	acyl-activating enzyme (AAE) consensus motif; other site
1171376000205	putative AMP binding site [chemical binding]; other site
1171376000206	putative active site [active]
1171376000207	putative CoA binding site [chemical binding]; other site
1171376000208	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
1171376000209	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1171376000210	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
1171376000211	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1171376000212	active site
1171376000213	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
1171376000214	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1171376000215	Ligand binding site [chemical binding]; other site
1171376000216	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1171376000217	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
1171376000218	Electron transfer flavoprotein domain; Region: ETF; smart00893
1171376000219	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1171376000220	putative oxidoreductase FixC; Provisional; Region: PRK10157
1171376000221	ferredoxin-like protein FixX; Provisional; Region: PRK15449
1171376000222	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376000223	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1171376000224	putative substrate translocation pore; other site
1171376000225	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1171376000226	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1171376000227	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1171376000228	Sulfatase; Region: Sulfatase; cl17466
1171376000229	Sulfatase; Region: Sulfatase; cl17466
1171376000230	Sulfatase; Region: Sulfatase; cl17466
1171376000231	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1171376000232	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1171376000233	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1171376000234	TrkA-N domain; Region: TrkA_N; pfam02254
1171376000235	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1171376000236	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1171376000237	folate binding site [chemical binding]; other site
1171376000238	NADP+ binding site [chemical binding]; other site
1171376000239	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1171376000240	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1171376000241	active site
1171376000242	metal binding site [ion binding]; metal-binding site
1171376000243	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1171376000244	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1171376000245	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1171376000246	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1171376000247	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1171376000248	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1171376000249	SurA N-terminal domain; Region: SurA_N; pfam09312
1171376000250	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1171376000251	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1171376000252	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1171376000253	OstA-like protein; Region: OstA; pfam03968
1171376000254	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1171376000255	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1171376000256	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1171376000257	putative metal binding site [ion binding]; other site
1171376000258	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1171376000259	HSP70 interaction site [polypeptide binding]; other site
1171376000260	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1171376000261	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1171376000262	active site
1171376000263	ATP-dependent helicase HepA; Validated; Region: PRK04914
1171376000264	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1171376000265	ATP binding site [chemical binding]; other site
1171376000266	putative Mg++ binding site [ion binding]; other site
1171376000267	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376000268	nucleotide binding region [chemical binding]; other site
1171376000269	ATP-binding site [chemical binding]; other site
1171376000270	DNA polymerase II; Reviewed; Region: PRK05762
1171376000271	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1171376000272	active site
1171376000273	catalytic site [active]
1171376000274	substrate binding site [chemical binding]; other site
1171376000275	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1171376000276	active site
1171376000277	metal-binding site
1171376000278	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1171376000279	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1171376000280	putative active site [active]
1171376000281	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1171376000282	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1171376000283	intersubunit interface [polypeptide binding]; other site
1171376000284	active site
1171376000285	Zn2+ binding site [ion binding]; other site
1171376000286	L-arabinose isomerase; Provisional; Region: PRK02929
1171376000287	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1171376000288	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1171376000289	trimer interface [polypeptide binding]; other site
1171376000290	putative substrate binding site [chemical binding]; other site
1171376000291	putative metal binding site [ion binding]; other site
1171376000292	ribulokinase; Provisional; Region: PRK04123
1171376000293	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1171376000294	N- and C-terminal domain interface [polypeptide binding]; other site
1171376000295	active site
1171376000296	MgATP binding site [chemical binding]; other site
1171376000297	catalytic site [active]
1171376000298	metal binding site [ion binding]; metal-binding site
1171376000299	carbohydrate binding site [chemical binding]; other site
1171376000300	homodimer interface [polypeptide binding]; other site
1171376000301	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1171376000302	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1171376000303	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376000304	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376000305	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1171376000306	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1171376000307	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1171376000308	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1171376000309	Walker A/P-loop; other site
1171376000310	ATP binding site [chemical binding]; other site
1171376000311	Q-loop/lid; other site
1171376000312	ABC transporter signature motif; other site
1171376000313	Walker B; other site
1171376000314	D-loop; other site
1171376000315	H-loop/switch region; other site
1171376000316	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1171376000317	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376000318	dimer interface [polypeptide binding]; other site
1171376000319	conserved gate region; other site
1171376000320	putative PBP binding loops; other site
1171376000321	ABC-ATPase subunit interface; other site
1171376000322	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376000323	dimer interface [polypeptide binding]; other site
1171376000324	conserved gate region; other site
1171376000325	putative PBP binding loops; other site
1171376000326	ABC-ATPase subunit interface; other site
1171376000327	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1171376000328	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1171376000329	transcriptional regulator SgrR; Provisional; Region: PRK13626
1171376000330	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1171376000331	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1171376000332	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1171376000333	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1171376000334	substrate binding site [chemical binding]; other site
1171376000335	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1171376000336	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1171376000337	substrate binding site [chemical binding]; other site
1171376000338	ligand binding site [chemical binding]; other site
1171376000339	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1171376000340	tartrate dehydrogenase; Region: TTC; TIGR02089
1171376000341	2-isopropylmalate synthase; Validated; Region: PRK00915
1171376000342	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1171376000343	active site
1171376000344	catalytic residues [active]
1171376000345	metal binding site [ion binding]; metal-binding site
1171376000346	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1171376000347	leu operon leader peptide; Provisional; Region: PRK14744
1171376000348	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1171376000349	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376000350	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1171376000351	putative substrate binding pocket [chemical binding]; other site
1171376000352	putative dimerization interface [polypeptide binding]; other site
1171376000353	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1171376000354	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1171376000355	dimer interface [polypeptide binding]; other site
1171376000356	PYR/PP interface [polypeptide binding]; other site
1171376000357	TPP binding site [chemical binding]; other site
1171376000358	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1171376000359	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1171376000360	TPP-binding site [chemical binding]; other site
1171376000361	dimer interface [polypeptide binding]; other site
1171376000362	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1171376000363	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1171376000364	putative valine binding site [chemical binding]; other site
1171376000365	dimer interface [polypeptide binding]; other site
1171376000366	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1171376000367	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1171376000368	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376000369	DNA binding site [nucleotide binding]
1171376000370	domain linker motif; other site
1171376000371	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1171376000372	dimerization interface [polypeptide binding]; other site
1171376000373	ligand binding site [chemical binding]; other site
1171376000374	mraZ protein; Region: TIGR00242
1171376000375	MraZ protein; Region: MraZ; pfam02381
1171376000376	MraZ protein; Region: MraZ; pfam02381
1171376000377	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1171376000378	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1171376000379	cell division protein FtsL; Provisional; Region: PRK10772
1171376000380	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1171376000381	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1171376000382	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1171376000383	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1171376000384	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1171376000385	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1171376000386	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1171376000387	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1171376000388	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1171376000389	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1171376000390	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1171376000391	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1171376000392	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1171376000393	Mg++ binding site [ion binding]; other site
1171376000394	putative catalytic motif [active]
1171376000395	putative substrate binding site [chemical binding]; other site
1171376000396	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1171376000397	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1171376000398	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1171376000399	cell division protein FtsW; Provisional; Region: PRK10774
1171376000400	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1171376000401	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1171376000402	active site
1171376000403	homodimer interface [polypeptide binding]; other site
1171376000404	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1171376000405	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1171376000406	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1171376000407	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1171376000408	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1171376000409	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1171376000410	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1171376000411	cell division protein FtsQ; Provisional; Region: PRK10775
1171376000412	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1171376000413	Cell division protein FtsQ; Region: FtsQ; pfam03799
1171376000414	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1171376000415	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1171376000416	Cell division protein FtsA; Region: FtsA; pfam14450
1171376000417	cell division protein FtsZ; Validated; Region: PRK09330
1171376000418	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1171376000419	nucleotide binding site [chemical binding]; other site
1171376000420	SulA interaction site; other site
1171376000421	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
1171376000422	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1171376000423	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1171376000424	SecA regulator SecM; Provisional; Region: PRK02943
1171376000425	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1171376000426	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1171376000427	SEC-C motif; Region: SEC-C; pfam02810
1171376000428	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1171376000429	active site
1171376000430	8-oxo-dGMP binding site [chemical binding]; other site
1171376000431	nudix motif; other site
1171376000432	metal binding site [ion binding]; metal-binding site
1171376000433	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cl00470
1171376000434	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376000435	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1171376000436	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
1171376000437	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1171376000438	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1171376000439	CoA-binding site [chemical binding]; other site
1171376000440	ATP-binding [chemical binding]; other site
1171376000441	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1171376000442	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1171376000443	active site
1171376000444	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1171376000445	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1171376000446	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1171376000447	hypothetical protein; Provisional; Region: PRK10436
1171376000448	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1171376000449	Walker A motif; other site
1171376000450	ATP binding site [chemical binding]; other site
1171376000451	Walker B motif; other site
1171376000452	putative major pilin subunit; Provisional; Region: PRK10574
1171376000453	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1171376000454	Pilin (bacterial filament); Region: Pilin; pfam00114
1171376000455	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1171376000456	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1171376000457	dimerization interface [polypeptide binding]; other site
1171376000458	active site
1171376000459	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1171376000460	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1171376000461	amidase catalytic site [active]
1171376000462	Zn binding residues [ion binding]; other site
1171376000463	substrate binding site [chemical binding]; other site
1171376000464	regulatory protein AmpE; Provisional; Region: PRK10987
1171376000465	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1171376000466	active site
1171376000467	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1171376000468	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376000469	putative substrate translocation pore; other site
1171376000470	aromatic amino acid transporter; Provisional; Region: PRK10238
1171376000471	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1171376000472	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376000473	DNA-binding site [nucleotide binding]; DNA binding site
1171376000474	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1171376000475	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1171376000476	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1171376000477	dimer interface [polypeptide binding]; other site
1171376000478	TPP-binding site [chemical binding]; other site
1171376000479	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1171376000480	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1171376000481	E3 interaction surface; other site
1171376000482	lipoyl attachment site [posttranslational modification]; other site
1171376000483	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1171376000484	E3 interaction surface; other site
1171376000485	lipoyl attachment site [posttranslational modification]; other site
1171376000486	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1171376000487	E3 interaction surface; other site
1171376000488	lipoyl attachment site [posttranslational modification]; other site
1171376000489	e3 binding domain; Region: E3_binding; pfam02817
1171376000490	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1171376000491	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1171376000492	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1171376000493	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376000494	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1171376000495	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1171376000496	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
1171376000497	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1171376000498	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1171376000499	substrate binding site [chemical binding]; other site
1171376000500	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1171376000501	substrate binding site [chemical binding]; other site
1171376000502	ligand binding site [chemical binding]; other site
1171376000503	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183
1171376000504	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
1171376000505	hypothetical protein; Provisional; Region: PRK05248
1171376000506	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
1171376000507	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1171376000508	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1171376000509	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
1171376000510	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1171376000511	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1171376000512	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376000513	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1171376000514	spermidine synthase; Provisional; Region: PRK00811
1171376000515	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376000516	S-adenosylmethionine binding site [chemical binding]; other site
1171376000517	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1171376000518	multicopper oxidase; Provisional; Region: PRK10965
1171376000519	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1171376000520	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1171376000521	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1171376000522	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1171376000523	Trp docking motif [polypeptide binding]; other site
1171376000524	putative active site [active]
1171376000525	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1171376000526	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1171376000527	active site
1171376000528	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1171376000529	active site clefts [active]
1171376000530	zinc binding site [ion binding]; other site
1171376000531	dimer interface [polypeptide binding]; other site
1171376000532	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1171376000533	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1171376000534	Walker A/P-loop; other site
1171376000535	ATP binding site [chemical binding]; other site
1171376000536	Q-loop/lid; other site
1171376000537	ABC transporter signature motif; other site
1171376000538	Walker B; other site
1171376000539	D-loop; other site
1171376000540	H-loop/switch region; other site
1171376000541	inner membrane transport permease; Provisional; Region: PRK15066
1171376000542	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1171376000543	putative fimbrial protein StiH; Provisional; Region: PRK15297
1171376000544	fimbrial outer membrane usher protein StiC; Provisional; Region: PRK15298
1171376000545	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376000546	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376000547	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376000548	fimbrial chaperone protein StiB; Provisional; Region: PRK15299
1171376000549	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376000550	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376000551	fimbrial protein StiA; Provisional; Region: PRK15300
1171376000552	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1171376000553	active pocket/dimerization site; other site
1171376000554	active site
1171376000555	phosphorylation site [posttranslational modification]
1171376000556	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1171376000557	putative active site [active]
1171376000558	putative metal binding site [ion binding]; other site
1171376000559	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1171376000560	tetramerization interface [polypeptide binding]; other site
1171376000561	active site
1171376000562	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1171376000563	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1171376000564	active site
1171376000565	ATP-binding site [chemical binding]; other site
1171376000566	pantoate-binding site; other site
1171376000567	HXXH motif; other site
1171376000568	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1171376000569	oligomerization interface [polypeptide binding]; other site
1171376000570	active site
1171376000571	metal binding site [ion binding]; metal-binding site
1171376000572	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1171376000573	catalytic center binding site [active]
1171376000574	ATP binding site [chemical binding]; other site
1171376000575	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
1171376000576	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1171376000577	active site
1171376000578	NTP binding site [chemical binding]; other site
1171376000579	metal binding triad [ion binding]; metal-binding site
1171376000580	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1171376000581	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1171376000582	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1171376000583	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1171376000584	active site
1171376000585	nucleotide binding site [chemical binding]; other site
1171376000586	HIGH motif; other site
1171376000587	KMSKS motif; other site
1171376000588	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1171376000589	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1171376000590	2'-5' RNA ligase; Provisional; Region: PRK15124
1171376000591	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1171376000592	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1171376000593	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1171376000594	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1171376000595	ATP binding site [chemical binding]; other site
1171376000596	putative Mg++ binding site [ion binding]; other site
1171376000597	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376000598	nucleotide binding region [chemical binding]; other site
1171376000599	ATP-binding site [chemical binding]; other site
1171376000600	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1171376000601	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1171376000602	Transglycosylase; Region: Transgly; pfam00912
1171376000603	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1171376000604	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1171376000605	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1171376000606	N-terminal plug; other site
1171376000607	ligand-binding site [chemical binding]; other site
1171376000608	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1171376000609	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1171376000610	Walker A/P-loop; other site
1171376000611	ATP binding site [chemical binding]; other site
1171376000612	Q-loop/lid; other site
1171376000613	ABC transporter signature motif; other site
1171376000614	Walker B; other site
1171376000615	D-loop; other site
1171376000616	H-loop/switch region; other site
1171376000617	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1171376000618	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1171376000619	siderophore binding site; other site
1171376000620	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1171376000621	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1171376000622	ABC-ATPase subunit  interface; other site
1171376000623	dimer interface [polypeptide binding]; other site
1171376000624	putative PBP binding regions; other site
1171376000625	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1171376000626	ABC-ATPase subunit  interface; other site
1171376000627	dimer interface [polypeptide binding]; other site
1171376000628	putative PBP binding regions; other site
1171376000629	putative fimbrial subunit StfA; Provisional; Region: PRK15283
1171376000630	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1171376000631	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376000632	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376000633	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376000634	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
1171376000635	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376000636	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376000637	putative minor fimbrial subunit StfE; Provisional; Region: PRK15286
1171376000638	putative minor fimbrial subunit StfF; Provisional; Region: PRK15287
1171376000639	putative minor fimbrial subunit StfG; Provisional; Region: PRK15288
1171376000640	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
1171376000641	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1171376000642	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1171376000643	inhibitor-cofactor binding pocket; inhibition site
1171376000644	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376000645	catalytic residue [active]
1171376000646	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1171376000647	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1171376000648	Cl- selectivity filter; other site
1171376000649	Cl- binding residues [ion binding]; other site
1171376000650	pore gating glutamate residue; other site
1171376000651	dimer interface [polypeptide binding]; other site
1171376000652	H+/Cl- coupling transport residue; other site
1171376000653	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1171376000654	hypothetical protein; Provisional; Region: PRK10578
1171376000655	UPF0126 domain; Region: UPF0126; pfam03458
1171376000656	UPF0126 domain; Region: UPF0126; pfam03458
1171376000657	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1171376000658	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1171376000659	cobalamin binding residues [chemical binding]; other site
1171376000660	putative BtuC binding residues; other site
1171376000661	dimer interface [polypeptide binding]; other site
1171376000662	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1171376000663	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1171376000664	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1171376000665	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1171376000666	Zn2+ binding site [ion binding]; other site
1171376000667	Mg2+ binding site [ion binding]; other site
1171376000668	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1171376000669	serine endoprotease; Provisional; Region: PRK10942
1171376000670	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1171376000671	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1171376000672	protein binding site [polypeptide binding]; other site
1171376000673	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1171376000674	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1171376000675	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1171376000676	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1171376000677	hypothetical protein; Provisional; Region: PRK13677
1171376000678	shikimate transporter; Provisional; Region: PRK09952
1171376000679	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376000680	putative substrate translocation pore; other site
1171376000681	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1171376000682	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1171376000683	trimer interface [polypeptide binding]; other site
1171376000684	active site
1171376000685	substrate binding site [chemical binding]; other site
1171376000686	CoA binding site [chemical binding]; other site
1171376000687	PII uridylyl-transferase; Provisional; Region: PRK05007
1171376000688	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1171376000689	metal binding triad; other site
1171376000690	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1171376000691	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1171376000692	Zn2+ binding site [ion binding]; other site
1171376000693	Mg2+ binding site [ion binding]; other site
1171376000694	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1171376000695	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1171376000696	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1171376000697	active site
1171376000698	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1171376000699	rRNA interaction site [nucleotide binding]; other site
1171376000700	S8 interaction site; other site
1171376000701	putative laminin-1 binding site; other site
1171376000702	elongation factor Ts; Provisional; Region: tsf; PRK09377
1171376000703	UBA/TS-N domain; Region: UBA; pfam00627
1171376000704	Elongation factor TS; Region: EF_TS; pfam00889
1171376000705	Elongation factor TS; Region: EF_TS; pfam00889
1171376000706	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1171376000707	putative nucleotide binding site [chemical binding]; other site
1171376000708	uridine monophosphate binding site [chemical binding]; other site
1171376000709	homohexameric interface [polypeptide binding]; other site
1171376000710	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1171376000711	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1171376000712	hinge region; other site
1171376000713	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1171376000714	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1171376000715	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1171376000716	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1171376000717	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1171376000718	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1171376000719	catalytic residue [active]
1171376000720	putative FPP diphosphate  binding site; other site
1171376000721	putative FPP binding hydrophobic cleft; other site
1171376000722	dimer interface [polypeptide binding]; other site
1171376000723	putative IPP diphosphate binding site; other site
1171376000724	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1171376000725	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1171376000726	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1171376000727	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1171376000728	active site
1171376000729	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1171376000730	protein binding site [polypeptide binding]; other site
1171376000731	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1171376000732	protein binding site [polypeptide binding]; other site
1171376000733	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1171376000734	putative substrate binding region [chemical binding]; other site
1171376000735	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1171376000736	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1171376000737	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1171376000738	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1171376000739	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1171376000740	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1171376000741	Surface antigen; Region: Bac_surface_Ag; pfam01103
1171376000742	periplasmic chaperone; Provisional; Region: PRK10780
1171376000743	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1171376000744	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1171376000745	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1171376000746	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1171376000747	trimer interface [polypeptide binding]; other site
1171376000748	active site
1171376000749	UDP-GlcNAc binding site [chemical binding]; other site
1171376000750	lipid binding site [chemical binding]; lipid-binding site
1171376000751	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1171376000752	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1171376000753	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1171376000754	active site
1171376000755	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1171376000756	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1171376000757	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1171376000758	RNA/DNA hybrid binding site [nucleotide binding]; other site
1171376000759	active site
1171376000760	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1171376000761	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1171376000762	putative active site [active]
1171376000763	putative PHP Thumb interface [polypeptide binding]; other site
1171376000764	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1171376000765	generic binding surface II; other site
1171376000766	generic binding surface I; other site
1171376000767	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1171376000768	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1171376000769	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1171376000770	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
1171376000771	putative sugar binding site [chemical binding]; other site
1171376000772	catalytic residues [active]
1171376000773	PKD domain; Region: PKD; pfam00801
1171376000774	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1171376000775	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1171376000776	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1171376000777	homodimer interface [polypeptide binding]; other site
1171376000778	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376000779	catalytic residue [active]
1171376000780	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1171376000781	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1171376000782	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1171376000783	putative metal binding site [ion binding]; other site
1171376000784	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1171376000785	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1171376000786	Ligand Binding Site [chemical binding]; other site
1171376000787	TilS substrate binding domain; Region: TilS; pfam09179
1171376000788	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1171376000789	Rho-binding antiterminator; Provisional; Region: PRK11625
1171376000790	hypothetical protein; Provisional; Region: PRK04964
1171376000791	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1171376000792	hypothetical protein; Provisional; Region: PRK09256
1171376000793	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1171376000794	potential frameshift: common BLAST hit: gi|194446048|ref|YP_002039481.1| lipoprotein involved with copper homeostasis and adhesion
1171376000795	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1171376000796	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1171376000797	dimer interface [polypeptide binding]; other site
1171376000798	motif 1; other site
1171376000799	active site
1171376000800	motif 2; other site
1171376000801	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1171376000802	putative deacylase active site [active]
1171376000803	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1171376000804	active site
1171376000805	motif 3; other site
1171376000806	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1171376000807	anticodon binding site; other site
1171376000808	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1171376000809	homodimer interaction site [polypeptide binding]; other site
1171376000810	cofactor binding site; other site
1171376000811	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1171376000812	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1171376000813	lipoprotein, YaeC family; Region: TIGR00363
1171376000814	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376000815	dimer interface [polypeptide binding]; other site
1171376000816	conserved gate region; other site
1171376000817	ABC-ATPase subunit interface; other site
1171376000818	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1171376000819	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1171376000820	Walker A/P-loop; other site
1171376000821	ATP binding site [chemical binding]; other site
1171376000822	Q-loop/lid; other site
1171376000823	ABC transporter signature motif; other site
1171376000824	Walker B; other site
1171376000825	D-loop; other site
1171376000826	H-loop/switch region; other site
1171376000827	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1171376000828	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1171376000829	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376000830	active site
1171376000831	motif I; other site
1171376000832	motif II; other site
1171376000833	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1171376000834	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1171376000835	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376000836	putative substrate translocation pore; other site
1171376000837	lipoprotein; Provisional; Region: PRK10759
1171376000838	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1171376000839	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1171376000840	domain interface [polypeptide binding]; other site
1171376000841	putative active site [active]
1171376000842	catalytic site [active]
1171376000843	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1171376000844	domain interface [polypeptide binding]; other site
1171376000845	putative active site [active]
1171376000846	catalytic site [active]
1171376000847	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1171376000848	CoA binding domain; Region: CoA_binding_2; pfam13380
1171376000849	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1171376000850	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1171376000851	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1171376000852	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376000853	Coenzyme A binding pocket [chemical binding]; other site
1171376000854	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1171376000855	thioredoxin 2; Provisional; Region: PRK10996
1171376000856	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1171376000857	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1171376000858	catalytic residues [active]
1171376000859	putative methyltransferase; Provisional; Region: PRK10864
1171376000860	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1171376000861	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1171376000862	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1171376000863	ligand binding site [chemical binding]; other site
1171376000864	active site
1171376000865	UGI interface [polypeptide binding]; other site
1171376000866	catalytic site [active]
1171376000867	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1171376000868	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
1171376000869	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376000870	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376000871	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1171376000872	dimerization interface [polypeptide binding]; other site
1171376000873	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1171376000874	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1171376000875	ATP binding site [chemical binding]; other site
1171376000876	Mg++ binding site [ion binding]; other site
1171376000877	motif III; other site
1171376000878	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376000879	nucleotide binding region [chemical binding]; other site
1171376000880	ATP-binding site [chemical binding]; other site
1171376000881	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1171376000882	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376000883	S-adenosylmethionine binding site [chemical binding]; other site
1171376000884	L-aspartate oxidase; Provisional; Region: PRK09077
1171376000885	L-aspartate oxidase; Provisional; Region: PRK06175
1171376000886	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1171376000887	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1171376000888	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1171376000889	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1171376000890	DNA binding residues [nucleotide binding]
1171376000891	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1171376000892	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1171376000893	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1171376000894	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1171376000895	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1171376000896	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1171376000897	integrase; Provisional; Region: PRK09692
1171376000898	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1171376000899	active site
1171376000900	Int/Topo IB signature motif; other site
1171376000901	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
1171376000902	potential frameshift: common BLAST hit: gi|378985199|ref|YP_005248355.1| Gifsy-1 prophage protein
1171376000903	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1171376000904	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
1171376000905	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376000906	non-specific DNA binding site [nucleotide binding]; other site
1171376000907	salt bridge; other site
1171376000908	sequence-specific DNA binding site [nucleotide binding]; other site
1171376000909	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1171376000910	DNA binding residues [nucleotide binding]
1171376000911	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1171376000912	primosomal protein DnaI; Provisional; Region: PRK02854
1171376000913	putative replication protein; Provisional; Region: PRK12377
1171376000914	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376000915	Walker A motif; other site
1171376000916	ATP binding site [chemical binding]; other site
1171376000917	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1171376000918	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1171376000919	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1171376000920	DinI-like family; Region: DinI; pfam06183
1171376000921	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1171376000922	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1171376000923	Antitermination protein; Region: Antiterm; pfam03589
1171376000924	Antitermination protein; Region: Antiterm; pfam03589
1171376000925	PipA protein; Region: PipA; pfam07108
1171376000926	phage holin, lambda family; Region: holin_lambda; TIGR01594
1171376000927	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1171376000928	catalytic residues [active]
1171376000929	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1171376000930	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1171376000931	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1171376000932	Domain of unknown function (DUF1859); Region: DUF1859; pfam08948
1171376000933	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1171376000934	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1171376000935	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1171376000936	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1171376000937	oligomer interface [polypeptide binding]; other site
1171376000938	active site residues [active]
1171376000939	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
1171376000940	Uncharacterized conserved protein [Function unknown]; Region: COG5471
1171376000941	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
1171376000942	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1171376000943	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1171376000944	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1171376000945	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
1171376000946	Minor tail protein T; Region: Phage_tail_T; cl05636
1171376000947	Phage-related minor tail protein [Function unknown]; Region: COG5281
1171376000948	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1171376000949	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1171376000950	Phage-related protein [Function unknown]; Region: COG4718
1171376000951	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1171376000952	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1171376000953	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1171376000954	E-class dimer interface [polypeptide binding]; other site
1171376000955	P-class dimer interface [polypeptide binding]; other site
1171376000956	active site
1171376000957	Cu2+ binding site [ion binding]; other site
1171376000958	Zn2+ binding site [ion binding]; other site
1171376000959	Phage-related protein [Function unknown]; Region: gp18; COG4672
1171376000960	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1171376000961	MPN+ (JAMM) motif; other site
1171376000962	Zinc-binding site [ion binding]; other site
1171376000963	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1171376000964	NlpC/P60 family; Region: NLPC_P60; cl17555
1171376000965	Phage-related protein, tail component [Function unknown]; Region: COG4723
1171376000966	Phage-related protein, tail component [Function unknown]; Region: COG4733
1171376000967	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1171376000968	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1171376000969	Interdomain contacts; other site
1171376000970	Cytokine receptor motif; other site
1171376000971	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1171376000972	Fibronectin type III protein; Region: DUF3672; pfam12421
1171376000973	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1171376000974	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1171376000975	Phage Tail Collar Domain; Region: Collar; pfam07484
1171376000976	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1171376000977	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
1171376000978	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1171376000979	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1171376000980	hypothetical protein; Provisional; Region: PRK09951
1171376000981	DinI-like family; Region: DinI; cl11630
1171376000982	aminopeptidase N; Provisional; Region: pepN; PRK14015
1171376000983	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1171376000984	active site
1171376000985	Zn binding site [ion binding]; other site
1171376000986	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1171376000987	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1171376000988	quinone interaction residues [chemical binding]; other site
1171376000989	active site
1171376000990	catalytic residues [active]
1171376000991	FMN binding site [chemical binding]; other site
1171376000992	substrate binding site [chemical binding]; other site
1171376000993	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1171376000994	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1171376000995	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1171376000996	MOSC domain; Region: MOSC; pfam03473
1171376000997	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1171376000998	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1171376000999	catalytic loop [active]
1171376001000	iron binding site [ion binding]; other site
1171376001001	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1171376001002	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1171376001003	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1171376001004	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376001005	S-adenosylmethionine binding site [chemical binding]; other site
1171376001006	ABC transporter ATPase component; Reviewed; Region: PRK11147
1171376001007	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376001008	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376001009	Walker A/P-loop; other site
1171376001010	Walker A/P-loop; other site
1171376001011	ATP binding site [chemical binding]; other site
1171376001012	ATP binding site [chemical binding]; other site
1171376001013	Q-loop/lid; other site
1171376001014	Q-loop/lid; other site
1171376001015	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1171376001016	ABC transporter signature motif; other site
1171376001017	Walker B; other site
1171376001018	D-loop; other site
1171376001019	ABC transporter; Region: ABC_tran_2; pfam12848
1171376001020	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1171376001021	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1171376001022	Paraquat-inducible protein A; Region: PqiA; pfam04403
1171376001023	Paraquat-inducible protein A; Region: PqiA; pfam04403
1171376001024	paraquat-inducible protein B; Provisional; Region: PRK10807
1171376001025	mce related protein; Region: MCE; pfam02470
1171376001026	mce related protein; Region: MCE; pfam02470
1171376001027	mce related protein; Region: MCE; pfam02470
1171376001028	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1171376001029	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1171376001030	ribosome modulation factor; Provisional; Region: PRK14563
1171376001031	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1171376001032	active site 1 [active]
1171376001033	dimer interface [polypeptide binding]; other site
1171376001034	active site 2 [active]
1171376001035	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1171376001036	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1171376001037	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1171376001038	outer membrane protein A; Reviewed; Region: PRK10808
1171376001039	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1171376001040	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1171376001041	ligand binding site [chemical binding]; other site
1171376001042	cell division inhibitor SulA; Region: sula; TIGR00623
1171376001043	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
1171376001044	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1171376001045	TIGR01666 family membrane protein; Region: YCCS
1171376001046	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1171376001047	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1171376001048	Predicted membrane protein [Function unknown]; Region: COG3304
1171376001049	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1171376001050	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1171376001051	DNA helicase IV; Provisional; Region: helD; PRK11054
1171376001052	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1171376001053	Part of AAA domain; Region: AAA_19; pfam13245
1171376001054	Family description; Region: UvrD_C_2; pfam13538
1171376001055	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1171376001056	active site
1171376001057	dimer interfaces [polypeptide binding]; other site
1171376001058	catalytic residues [active]
1171376001059	hypothetical protein; Provisional; Region: PRK03641
1171376001060	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
1171376001061	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1171376001062	heat shock protein HspQ; Provisional; Region: PRK14129
1171376001063	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1171376001064	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1171376001065	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1171376001066	putative RNA binding site [nucleotide binding]; other site
1171376001067	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376001068	S-adenosylmethionine binding site [chemical binding]; other site
1171376001069	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1171376001070	substrate binding site [chemical binding]; other site
1171376001071	Cupin domain; Region: Cupin_2; cl17218
1171376001072	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1171376001073	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376001074	acylphosphatase; Provisional; Region: PRK14426
1171376001075	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1171376001076	sulfur transfer protein TusE; Provisional; Region: PRK11508
1171376001077	YccA-like proteins; Region: YccA_like; cd10433
1171376001078	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1171376001079	PipA protein; Region: PipA; pfam07108
1171376001080	secreted effector protein PipB; Provisional; Region: PRK15197
1171376001081	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1171376001082	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1171376001083	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1171376001084	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
1171376001085	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
1171376001086	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
1171376001087	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
1171376001088	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
1171376001089	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1171376001090	HAMP domain; Region: HAMP; pfam00672
1171376001091	dimerization interface [polypeptide binding]; other site
1171376001092	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376001093	dimer interface [polypeptide binding]; other site
1171376001094	phosphorylation site [posttranslational modification]
1171376001095	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376001096	ATP binding site [chemical binding]; other site
1171376001097	Mg2+ binding site [ion binding]; other site
1171376001098	G-X-G motif; other site
1171376001099	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
1171376001100	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376001101	active site
1171376001102	phosphorylation site [posttranslational modification]
1171376001103	intermolecular recognition site; other site
1171376001104	dimerization interface [polypeptide binding]; other site
1171376001105	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376001106	DNA binding site [nucleotide binding]
1171376001107	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1171376001108	active site
1171376001109	homotetramer interface [polypeptide binding]; other site
1171376001110	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
1171376001111	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
1171376001112	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1171376001113	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1171376001114	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1171376001115	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
1171376001116	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1171376001117	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1171376001118	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
1171376001119	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
1171376001120	NAD binding site [chemical binding]; other site
1171376001121	catalytic residues [active]
1171376001122	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
1171376001123	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1171376001124	putative active site [active]
1171376001125	putative metal binding site [ion binding]; other site
1171376001126	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
1171376001127	putative substrate binding pocket [chemical binding]; other site
1171376001128	trimer interface [polypeptide binding]; other site
1171376001129	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
1171376001130	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1171376001131	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376001132	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1171376001133	putative substrate translocation pore; other site
1171376001134	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
1171376001135	Cupin domain; Region: Cupin_2; pfam07883
1171376001136	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376001137	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
1171376001138	anti-adapter protein IraM; Provisional; Region: PRK09919
1171376001139	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
1171376001140	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
1171376001141	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
1171376001142	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1171376001143	HSP70 interaction site [polypeptide binding]; other site
1171376001144	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1171376001145	substrate binding site [polypeptide binding]; other site
1171376001146	dimer interface [polypeptide binding]; other site
1171376001147	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
1171376001148	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1171376001149	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1171376001150	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1171376001151	DsbD alpha interface [polypeptide binding]; other site
1171376001152	catalytic residues [active]
1171376001153	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
1171376001154	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1171376001155	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1171376001156	catalytic residues [active]
1171376001157	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1171376001158	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1171376001159	catalytic residues [active]
1171376001160	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1171376001161	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1171376001162	catalytic core [active]
1171376001163	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1171376001164	hypothetical protein; Provisional; Region: PRK10174
1171376001165	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1171376001166	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1171376001167	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1171376001168	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376001169	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1171376001170	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1171376001171	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1171376001172	Predicted transcriptional regulator [Transcription]; Region: COG3905
1171376001173	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1171376001174	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1171376001175	Glutamate binding site [chemical binding]; other site
1171376001176	NAD binding site [chemical binding]; other site
1171376001177	catalytic residues [active]
1171376001178	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1171376001179	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1171376001180	Na binding site [ion binding]; other site
1171376001181	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
1171376001182	hypothetical protein; Provisional; Region: PRK10536
1171376001183	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1171376001184	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1171376001185	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1171376001186	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1171376001187	putative active site [active]
1171376001188	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
1171376001189	Na binding site [ion binding]; other site
1171376001190	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1171376001191	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1171376001192	putative active site cavity [active]
1171376001193	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
1171376001194	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
1171376001195	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1171376001196	putative sialic acid transporter; Provisional; Region: PRK12307
1171376001197	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376001198	putative substrate translocation pore; other site
1171376001199	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1171376001200	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1171376001201	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1171376001202	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1171376001203	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1171376001204	putative ligand binding site [chemical binding]; other site
1171376001205	NAD binding site [chemical binding]; other site
1171376001206	dimerization interface [polypeptide binding]; other site
1171376001207	catalytic site [active]
1171376001208	putative hydrolase; Validated; Region: PRK09248
1171376001209	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1171376001210	active site
1171376001211	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1171376001212	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1171376001213	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
1171376001214	curli assembly protein CsgF; Provisional; Region: PRK10050
1171376001215	curli assembly protein CsgE; Provisional; Region: PRK10386
1171376001216	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1171376001217	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376001218	DNA binding residues [nucleotide binding]
1171376001219	dimerization interface [polypeptide binding]; other site
1171376001220	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1171376001221	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1171376001222	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1171376001223	major curlin subunit; Provisional; Region: csgA; PRK10051
1171376001224	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1171376001225	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
1171376001226	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1171376001227	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1171376001228	putative ADP-ribose binding site [chemical binding]; other site
1171376001229	putative active site [active]
1171376001230	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
1171376001231	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1171376001232	putative active site [active]
1171376001233	catalytic site [active]
1171376001234	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1171376001235	putative active site [active]
1171376001236	catalytic site [active]
1171376001237	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1171376001238	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1171376001239	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1171376001240	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
1171376001241	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1171376001242	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1171376001243	Ligand binding site; other site
1171376001244	DXD motif; other site
1171376001245	lipoprotein; Provisional; Region: PRK10175
1171376001246	secY/secA suppressor protein; Provisional; Region: PRK11467
1171376001247	drug efflux system protein MdtG; Provisional; Region: PRK09874
1171376001248	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376001249	putative substrate translocation pore; other site
1171376001250	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1171376001251	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1171376001252	putative acyl-acceptor binding pocket; other site
1171376001253	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1171376001254	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1171376001255	active site residue [active]
1171376001256	hypothetical protein; Provisional; Region: PRK03757
1171376001257	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1171376001258	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
1171376001259	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1171376001260	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1171376001261	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1171376001262	DNA damage-inducible protein I; Provisional; Region: PRK10597
1171376001263	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1171376001264	active site
1171376001265	substrate binding pocket [chemical binding]; other site
1171376001266	dimer interface [polypeptide binding]; other site
1171376001267	lipoprotein; Provisional; Region: PRK10598
1171376001268	glutaredoxin 2; Provisional; Region: PRK10387
1171376001269	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1171376001270	C-terminal domain interface [polypeptide binding]; other site
1171376001271	GSH binding site (G-site) [chemical binding]; other site
1171376001272	catalytic residues [active]
1171376001273	putative dimer interface [polypeptide binding]; other site
1171376001274	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1171376001275	N-terminal domain interface [polypeptide binding]; other site
1171376001276	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1171376001277	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376001278	putative substrate translocation pore; other site
1171376001279	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1171376001280	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1171376001281	hypothetical protein; Provisional; Region: PRK11239
1171376001282	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1171376001283	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1171376001284	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1171376001285	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1171376001286	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1171376001287	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1171376001288	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
1171376001289	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
1171376001290	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
1171376001291	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1171376001292	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1171376001293	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1171376001294	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1171376001295	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1171376001296	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1171376001297	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1171376001298	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
1171376001299	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1171376001300	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1171376001301	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1171376001302	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1171376001303	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1171376001304	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1171376001305	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1171376001306	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1171376001307	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1171376001308	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1171376001309	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1171376001310	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1171376001311	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1171376001312	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1171376001313	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1171376001314	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1171376001315	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1171376001316	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1171376001317	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1171376001318	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1171376001319	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1171376001320	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1171376001321	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1171376001322	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1171376001323	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1171376001324	homodimer interface [polypeptide binding]; other site
1171376001325	oligonucleotide binding site [chemical binding]; other site
1171376001326	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1171376001327	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1171376001328	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1171376001329	RNA binding surface [nucleotide binding]; other site
1171376001330	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1171376001331	active site
1171376001332	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1171376001333	Maf-like protein; Region: Maf; pfam02545
1171376001334	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1171376001335	active site
1171376001336	dimer interface [polypeptide binding]; other site
1171376001337	hypothetical protein; Provisional; Region: PRK11193
1171376001338	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1171376001339	putative phosphate acyltransferase; Provisional; Region: PRK05331
1171376001340	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1171376001341	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1171376001342	dimer interface [polypeptide binding]; other site
1171376001343	active site
1171376001344	CoA binding pocket [chemical binding]; other site
1171376001345	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1171376001346	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1171376001347	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1171376001348	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1171376001349	NAD(P) binding site [chemical binding]; other site
1171376001350	homotetramer interface [polypeptide binding]; other site
1171376001351	homodimer interface [polypeptide binding]; other site
1171376001352	active site
1171376001353	acyl carrier protein; Provisional; Region: acpP; PRK00982
1171376001354	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1171376001355	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1171376001356	dimer interface [polypeptide binding]; other site
1171376001357	active site
1171376001358	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1171376001359	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1171376001360	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376001361	catalytic residue [active]
1171376001362	conserved hypothetical protein, YceG family; Region: TIGR00247
1171376001363	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1171376001364	dimerization interface [polypeptide binding]; other site
1171376001365	thymidylate kinase; Validated; Region: tmk; PRK00698
1171376001366	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1171376001367	TMP-binding site; other site
1171376001368	ATP-binding site [chemical binding]; other site
1171376001369	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1171376001370	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1171376001371	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1171376001372	active site
1171376001373	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1171376001374	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1171376001375	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1171376001376	active site turn [active]
1171376001377	phosphorylation site [posttranslational modification]
1171376001378	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1171376001379	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1171376001380	N-terminal plug; other site
1171376001381	ligand-binding site [chemical binding]; other site
1171376001382	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1171376001383	nucleotide binding site/active site [active]
1171376001384	HIT family signature motif; other site
1171376001385	catalytic residue [active]
1171376001386	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1171376001387	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1171376001388	putative dimer interface [polypeptide binding]; other site
1171376001389	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1171376001390	thiamine kinase; Region: ycfN_thiK; TIGR02721
1171376001391	thiamine kinase; Provisional; Region: thiK; PRK10271
1171376001392	substrate binding site [chemical binding]; other site
1171376001393	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1171376001394	beta-hexosaminidase; Provisional; Region: PRK05337
1171376001395	hypothetical protein; Provisional; Region: PRK04940
1171376001396	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1171376001397	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376001398	hypothetical protein; Provisional; Region: PRK11280
1171376001399	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1171376001400	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376001401	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1171376001402	L,D-transpeptidase; Provisional; Region: PRK10190
1171376001403	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1171376001404	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1171376001405	transcription-repair coupling factor; Provisional; Region: PRK10689
1171376001406	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1171376001407	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1171376001408	ATP binding site [chemical binding]; other site
1171376001409	putative Mg++ binding site [ion binding]; other site
1171376001410	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376001411	nucleotide binding region [chemical binding]; other site
1171376001412	ATP-binding site [chemical binding]; other site
1171376001413	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1171376001414	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1171376001415	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1171376001416	FtsX-like permease family; Region: FtsX; pfam02687
1171376001417	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1171376001418	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1171376001419	Walker A/P-loop; other site
1171376001420	ATP binding site [chemical binding]; other site
1171376001421	Q-loop/lid; other site
1171376001422	ABC transporter signature motif; other site
1171376001423	Walker B; other site
1171376001424	D-loop; other site
1171376001425	H-loop/switch region; other site
1171376001426	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1171376001427	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1171376001428	FtsX-like permease family; Region: FtsX; pfam02687
1171376001429	fructokinase; Reviewed; Region: PRK09557
1171376001430	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1171376001431	nucleotide binding site [chemical binding]; other site
1171376001432	NAD-dependent deacetylase; Provisional; Region: PRK00481
1171376001433	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1171376001434	NAD+ binding site [chemical binding]; other site
1171376001435	substrate binding site [chemical binding]; other site
1171376001436	Zn binding site [ion binding]; other site
1171376001437	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1171376001438	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1171376001439	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1171376001440	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376001441	dimer interface [polypeptide binding]; other site
1171376001442	conserved gate region; other site
1171376001443	putative PBP binding loops; other site
1171376001444	ABC-ATPase subunit interface; other site
1171376001445	Sif protein; Region: Sif; pfam06767
1171376001446	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1171376001447	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376001448	dimer interface [polypeptide binding]; other site
1171376001449	conserved gate region; other site
1171376001450	putative PBP binding loops; other site
1171376001451	ABC-ATPase subunit interface; other site
1171376001452	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1171376001453	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376001454	Walker A/P-loop; other site
1171376001455	ATP binding site [chemical binding]; other site
1171376001456	Q-loop/lid; other site
1171376001457	ABC transporter signature motif; other site
1171376001458	Walker B; other site
1171376001459	D-loop; other site
1171376001460	H-loop/switch region; other site
1171376001461	TOBE domain; Region: TOBE_2; pfam08402
1171376001462	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1171376001463	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1171376001464	metal binding site [ion binding]; metal-binding site
1171376001465	dimer interface [polypeptide binding]; other site
1171376001466	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1171376001467	Cupin-like domain; Region: Cupin_8; pfam13621
1171376001468	sensor protein PhoQ; Provisional; Region: PRK10815
1171376001469	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1171376001470	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1171376001471	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376001472	ATP binding site [chemical binding]; other site
1171376001473	Mg2+ binding site [ion binding]; other site
1171376001474	G-X-G motif; other site
1171376001475	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1171376001476	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376001477	active site
1171376001478	phosphorylation site [posttranslational modification]
1171376001479	intermolecular recognition site; other site
1171376001480	dimerization interface [polypeptide binding]; other site
1171376001481	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376001482	DNA binding site [nucleotide binding]
1171376001483	adenylosuccinate lyase; Provisional; Region: PRK09285
1171376001484	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1171376001485	tetramer interface [polypeptide binding]; other site
1171376001486	active site
1171376001487	putative lysogenization regulator; Reviewed; Region: PRK00218
1171376001488	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1171376001489	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1171376001490	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1171376001491	nudix motif; other site
1171376001492	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
1171376001493	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1171376001494	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1171376001495	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1171376001496	probable active site [active]
1171376001497	isocitrate dehydrogenase; Validated; Region: PRK07362
1171376001498	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1171376001499	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
1171376001500	DinI-like family; Region: DinI; pfam06183
1171376001501	Ricin-type beta-trefoil; Region: RICIN; smart00458
1171376001502	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1171376001503	putative sugar binding sites [chemical binding]; other site
1171376001504	Q-X-W motif; other site
1171376001505	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1171376001506	DNA-binding site [nucleotide binding]; DNA binding site
1171376001507	RNA-binding motif; other site
1171376001508	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1171376001509	lysozyme inhibitor; Provisional; Region: PRK13791
1171376001510	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1171376001511	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1171376001512	putative dimer interface [polypeptide binding]; other site
1171376001513	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
1171376001514	BNR repeat-like domain; Region: BNR_2; pfam13088
1171376001515	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1171376001516	TRL-like protein family; Region: TRL; pfam13146
1171376001517	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
1171376001518	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1171376001519	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1171376001520	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376001521	dimer interface [polypeptide binding]; other site
1171376001522	conserved gate region; other site
1171376001523	ABC-ATPase subunit interface; other site
1171376001524	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1171376001525	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376001526	dimer interface [polypeptide binding]; other site
1171376001527	conserved gate region; other site
1171376001528	putative PBP binding loops; other site
1171376001529	ABC-ATPase subunit interface; other site
1171376001530	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1171376001531	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
1171376001532	Walker A/P-loop; other site
1171376001533	ATP binding site [chemical binding]; other site
1171376001534	Q-loop/lid; other site
1171376001535	ABC transporter signature motif; other site
1171376001536	Walker B; other site
1171376001537	D-loop; other site
1171376001538	H-loop/switch region; other site
1171376001539	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376001540	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1171376001541	Walker A/P-loop; other site
1171376001542	ATP binding site [chemical binding]; other site
1171376001543	Q-loop/lid; other site
1171376001544	ABC transporter signature motif; other site
1171376001545	Walker B; other site
1171376001546	D-loop; other site
1171376001547	H-loop/switch region; other site
1171376001548	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1171376001549	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1171376001550	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
1171376001551	dimerization interface [polypeptide binding]; other site
1171376001552	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1171376001553	aminoglycoside resistance protein; Provisional; Region: PRK13746
1171376001554	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1171376001555	active site
1171376001556	NTP binding site [chemical binding]; other site
1171376001557	metal binding triad [ion binding]; metal-binding site
1171376001558	antibiotic binding site [chemical binding]; other site
1171376001559	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1171376001560	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376001561	DNA binding residues [nucleotide binding]
1171376001562	transcriptional regulator MirA; Provisional; Region: PRK15043
1171376001563	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
1171376001564	DNA binding residues [nucleotide binding]
1171376001565	dimer interface [polypeptide binding]; other site
1171376001566	Pleckstrin homology-like domain; Region: PH-like; cl17171
1171376001567	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1171376001568	chorismate mutase; Provisional; Region: PRK08055
1171376001569	leucine export protein LeuE; Provisional; Region: PRK10958
1171376001570	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1171376001571	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1171376001572	hypothetical protein; Provisional; Region: PRK10457
1171376001573	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1171376001574	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1171376001575	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1171376001576	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1171376001577	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1171376001578	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376001579	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1171376001580	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376001581	Predicted membrane protein [Function unknown]; Region: COG2707
1171376001582	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1171376001583	putative deacylase active site [active]
1171376001584	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1171376001585	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376001586	metal binding site [ion binding]; metal-binding site
1171376001587	active site
1171376001588	I-site; other site
1171376001589	hypothetical protein; Provisional; Region: PRK05325
1171376001590	PrkA family serine protein kinase; Provisional; Region: PRK15455
1171376001591	AAA ATPase domain; Region: AAA_16; pfam13191
1171376001592	Walker A motif; other site
1171376001593	ATP binding site [chemical binding]; other site
1171376001594	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1171376001595	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1171376001596	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1171376001597	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376001598	FeS/SAM binding site; other site
1171376001599	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1171376001600	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1171376001601	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1171376001602	active site
1171376001603	catalytic tetrad [active]
1171376001604	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1171376001605	active site
1171376001606	phosphate binding residues; other site
1171376001607	catalytic residues [active]
1171376001608	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1171376001609	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1171376001610	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1171376001611	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1171376001612	SelR domain; Region: SelR; pfam01641
1171376001613	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1171376001614	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1171376001615	metal binding site [ion binding]; metal-binding site
1171376001616	Isochorismatase family; Region: Isochorismatase; pfam00857
1171376001617	catalytic triad [active]
1171376001618	conserved cis-peptide bond; other site
1171376001619	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1171376001620	active site
1171376001621	homodimer interface [polypeptide binding]; other site
1171376001622	protease 4; Provisional; Region: PRK10949
1171376001623	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1171376001624	tandem repeat interface [polypeptide binding]; other site
1171376001625	oligomer interface [polypeptide binding]; other site
1171376001626	active site residues [active]
1171376001627	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1171376001628	tandem repeat interface [polypeptide binding]; other site
1171376001629	oligomer interface [polypeptide binding]; other site
1171376001630	active site residues [active]
1171376001631	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1171376001632	putative FMN binding site [chemical binding]; other site
1171376001633	selenophosphate synthetase; Provisional; Region: PRK00943
1171376001634	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1171376001635	dimerization interface [polypeptide binding]; other site
1171376001636	putative ATP binding site [chemical binding]; other site
1171376001637	DNA topoisomerase III; Provisional; Region: PRK07726
1171376001638	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1171376001639	active site
1171376001640	putative interdomain interaction site [polypeptide binding]; other site
1171376001641	putative metal-binding site [ion binding]; other site
1171376001642	putative nucleotide binding site [chemical binding]; other site
1171376001643	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1171376001644	domain I; other site
1171376001645	DNA binding groove [nucleotide binding]
1171376001646	phosphate binding site [ion binding]; other site
1171376001647	domain II; other site
1171376001648	domain III; other site
1171376001649	nucleotide binding site [chemical binding]; other site
1171376001650	catalytic site [active]
1171376001651	domain IV; other site
1171376001652	glutamate dehydrogenase; Provisional; Region: PRK09414
1171376001653	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1171376001654	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1171376001655	NAD(P) binding site [chemical binding]; other site
1171376001656	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1171376001657	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1171376001658	active site
1171376001659	8-oxo-dGMP binding site [chemical binding]; other site
1171376001660	nudix motif; other site
1171376001661	metal binding site [ion binding]; metal-binding site
1171376001662	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1171376001663	putative catalytic site [active]
1171376001664	putative phosphate binding site [ion binding]; other site
1171376001665	active site
1171376001666	metal binding site A [ion binding]; metal-binding site
1171376001667	DNA binding site [nucleotide binding]
1171376001668	putative AP binding site [nucleotide binding]; other site
1171376001669	putative metal binding site B [ion binding]; other site
1171376001670	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1171376001671	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1171376001672	inhibitor-cofactor binding pocket; inhibition site
1171376001673	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376001674	catalytic residue [active]
1171376001675	arginine succinyltransferase; Provisional; Region: PRK10456
1171376001676	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
1171376001677	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1171376001678	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1171376001679	NAD(P) binding site [chemical binding]; other site
1171376001680	catalytic residues [active]
1171376001681	succinylarginine dihydrolase; Provisional; Region: PRK13281
1171376001682	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1171376001683	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1171376001684	putative active site [active]
1171376001685	Zn binding site [ion binding]; other site
1171376001686	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1171376001687	dimer interface [polypeptide binding]; other site
1171376001688	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1171376001689	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1171376001690	GIY-YIG motif/motif A; other site
1171376001691	active site
1171376001692	catalytic site [active]
1171376001693	putative DNA binding site [nucleotide binding]; other site
1171376001694	metal binding site [ion binding]; metal-binding site
1171376001695	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1171376001696	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1171376001697	homodimer interface [polypeptide binding]; other site
1171376001698	NAD binding pocket [chemical binding]; other site
1171376001699	ATP binding pocket [chemical binding]; other site
1171376001700	Mg binding site [ion binding]; other site
1171376001701	active-site loop [active]
1171376001702	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1171376001703	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1171376001704	active site
1171376001705	P-loop; other site
1171376001706	phosphorylation site [posttranslational modification]
1171376001707	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1171376001708	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1171376001709	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1171376001710	methionine cluster; other site
1171376001711	active site
1171376001712	phosphorylation site [posttranslational modification]
1171376001713	metal binding site [ion binding]; metal-binding site
1171376001714	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1171376001715	Cupin domain; Region: Cupin_2; pfam07883
1171376001716	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376001717	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1171376001718	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1171376001719	NAD binding site [chemical binding]; other site
1171376001720	sugar binding site [chemical binding]; other site
1171376001721	divalent metal binding site [ion binding]; other site
1171376001722	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1171376001723	dimer interface [polypeptide binding]; other site
1171376001724	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1171376001725	putative active site [active]
1171376001726	YdjC motif; other site
1171376001727	Mg binding site [ion binding]; other site
1171376001728	putative homodimer interface [polypeptide binding]; other site
1171376001729	hydroperoxidase II; Provisional; Region: katE; PRK11249
1171376001730	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1171376001731	tetramer interface [polypeptide binding]; other site
1171376001732	heme binding pocket [chemical binding]; other site
1171376001733	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1171376001734	domain interactions; other site
1171376001735	cell division modulator; Provisional; Region: PRK10113
1171376001736	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1171376001737	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1171376001738	inner membrane protein; Provisional; Region: PRK11648
1171376001739	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1171376001740	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1171376001741	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376001742	motif II; other site
1171376001743	YniB-like protein; Region: YniB; pfam14002
1171376001744	Phosphotransferase enzyme family; Region: APH; pfam01636
1171376001745	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1171376001746	active site
1171376001747	ATP binding site [chemical binding]; other site
1171376001748	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1171376001749	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1171376001750	6-phosphofructokinase 2; Provisional; Region: PRK10294
1171376001751	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1171376001752	putative substrate binding site [chemical binding]; other site
1171376001753	putative ATP binding site [chemical binding]; other site
1171376001754	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1171376001755	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
1171376001756	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
1171376001757	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1171376001758	active site
1171376001759	substrate binding site [chemical binding]; other site
1171376001760	Mg2+ binding site [ion binding]; other site
1171376001761	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1171376001762	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1171376001763	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1171376001764	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1171376001765	active site
1171376001766	dimer interface [polypeptide binding]; other site
1171376001767	motif 1; other site
1171376001768	motif 2; other site
1171376001769	motif 3; other site
1171376001770	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1171376001771	anticodon binding site; other site
1171376001772	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1171376001773	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1171376001774	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1171376001775	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1171376001776	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1171376001777	23S rRNA binding site [nucleotide binding]; other site
1171376001778	L21 binding site [polypeptide binding]; other site
1171376001779	L13 binding site [polypeptide binding]; other site
1171376001780	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1171376001781	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1171376001782	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1171376001783	dimer interface [polypeptide binding]; other site
1171376001784	motif 1; other site
1171376001785	active site
1171376001786	motif 2; other site
1171376001787	motif 3; other site
1171376001788	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1171376001789	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1171376001790	putative tRNA-binding site [nucleotide binding]; other site
1171376001791	B3/4 domain; Region: B3_4; pfam03483
1171376001792	tRNA synthetase B5 domain; Region: B5; smart00874
1171376001793	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1171376001794	dimer interface [polypeptide binding]; other site
1171376001795	motif 1; other site
1171376001796	motif 3; other site
1171376001797	motif 2; other site
1171376001798	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1171376001799	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1171376001800	IHF dimer interface [polypeptide binding]; other site
1171376001801	IHF - DNA interface [nucleotide binding]; other site
1171376001802	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1171376001803	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1171376001804	ABC-ATPase subunit  interface; other site
1171376001805	dimer interface [polypeptide binding]; other site
1171376001806	putative PBP binding regions; other site
1171376001807	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1171376001808	catalytic residues [active]
1171376001809	dimer interface [polypeptide binding]; other site
1171376001810	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
1171376001811	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1171376001812	Walker A/P-loop; other site
1171376001813	ATP binding site [chemical binding]; other site
1171376001814	Q-loop/lid; other site
1171376001815	ABC transporter signature motif; other site
1171376001816	Walker B; other site
1171376001817	D-loop; other site
1171376001818	H-loop/switch region; other site
1171376001819	NlpC/P60 family; Region: NLPC_P60; pfam00877
1171376001820	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
1171376001821	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1171376001822	hypothetical protein; Validated; Region: PRK00029
1171376001823	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
1171376001824	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1171376001825	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1171376001826	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1171376001827	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1171376001828	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1171376001829	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1171376001830	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1171376001831	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
1171376001832	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
1171376001833	acyl-activating enzyme (AAE) consensus motif; other site
1171376001834	putative AMP binding site [chemical binding]; other site
1171376001835	putative active site [active]
1171376001836	putative CoA binding site [chemical binding]; other site
1171376001837	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1171376001838	oxidoreductase; Provisional; Region: PRK10015
1171376001839	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
1171376001840	Electron transfer flavoprotein domain; Region: ETF; smart00893
1171376001841	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1171376001842	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1171376001843	Ligand binding site [chemical binding]; other site
1171376001844	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1171376001845	Cupin domain; Region: Cupin_2; pfam07883
1171376001846	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1171376001847	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376001848	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
1171376001849	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1171376001850	active site
1171376001851	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1171376001852	Coenzyme A transferase; Region: CoA_trans; smart00882
1171376001853	Coenzyme A transferase; Region: CoA_trans; cl17247
1171376001854	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1171376001855	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1171376001856	active site
1171376001857	catalytic residue [active]
1171376001858	dimer interface [polypeptide binding]; other site
1171376001859	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
1171376001860	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1171376001861	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1171376001862	shikimate binding site; other site
1171376001863	NAD(P) binding site [chemical binding]; other site
1171376001864	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376001865	putative transporter; Provisional; Region: PRK03699
1171376001866	putative substrate translocation pore; other site
1171376001867	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376001868	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1171376001869	putative substrate translocation pore; other site
1171376001870	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
1171376001871	putative inner membrane protein; Provisional; Region: PRK10983
1171376001872	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1171376001873	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1171376001874	FAD binding domain; Region: FAD_binding_4; pfam01565
1171376001875	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1171376001876	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1171376001877	CoenzymeA binding site [chemical binding]; other site
1171376001878	subunit interaction site [polypeptide binding]; other site
1171376001879	PHB binding site; other site
1171376001880	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1171376001881	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1171376001882	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1171376001883	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1171376001884	putative ABC transporter; Region: ycf24; CHL00085
1171376001885	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1171376001886	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1171376001887	Walker A/P-loop; other site
1171376001888	ATP binding site [chemical binding]; other site
1171376001889	Q-loop/lid; other site
1171376001890	ABC transporter signature motif; other site
1171376001891	Walker B; other site
1171376001892	D-loop; other site
1171376001893	H-loop/switch region; other site
1171376001894	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1171376001895	FeS assembly protein SufD; Region: sufD; TIGR01981
1171376001896	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1171376001897	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1171376001898	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1171376001899	catalytic residue [active]
1171376001900	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1171376001901	L,D-transpeptidase; Provisional; Region: PRK10190
1171376001902	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1171376001903	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1171376001904	murein lipoprotein; Provisional; Region: PRK15396
1171376001905	murein lipoprotein; Provisional; Region: PRK15396
1171376001906	pyruvate kinase; Provisional; Region: PRK09206
1171376001907	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1171376001908	domain interfaces; other site
1171376001909	active site
1171376001910	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1171376001911	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1171376001912	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1171376001913	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1171376001914	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1171376001915	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376001916	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1171376001917	substrate binding site [chemical binding]; other site
1171376001918	dimer interface [polypeptide binding]; other site
1171376001919	ATP binding site [chemical binding]; other site
1171376001920	tetrathionate reductase subunit A; Provisional; Region: PRK14991
1171376001921	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
1171376001922	putative [Fe4-S4] binding site [ion binding]; other site
1171376001923	putative molybdopterin cofactor binding site [chemical binding]; other site
1171376001924	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
1171376001925	putative molybdopterin cofactor binding site; other site
1171376001926	tetrathionate reductase subunit C; Provisional; Region: PRK14992
1171376001927	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1171376001928	tetrathionate reductase subunit B; Provisional; Region: PRK14993
1171376001929	4Fe-4S binding domain; Region: Fer4; pfam00037
1171376001930	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1171376001931	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1171376001932	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1171376001933	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376001934	dimer interface [polypeptide binding]; other site
1171376001935	phosphorylation site [posttranslational modification]
1171376001936	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376001937	ATP binding site [chemical binding]; other site
1171376001938	Mg2+ binding site [ion binding]; other site
1171376001939	G-X-G motif; other site
1171376001940	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1171376001941	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376001942	active site
1171376001943	phosphorylation site [posttranslational modification]
1171376001944	intermolecular recognition site; other site
1171376001945	dimerization interface [polypeptide binding]; other site
1171376001946	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376001947	DNA binding residues [nucleotide binding]
1171376001948	dimerization interface [polypeptide binding]; other site
1171376001949	hypothetical protein; Provisional; Region: PRK10292
1171376001950	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1171376001951	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1171376001952	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
1171376001953	transcriptional regulator MirA; Provisional; Region: PRK15043
1171376001954	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1171376001955	DNA binding residues [nucleotide binding]
1171376001956	two component system sensor kinase SsrB; Provisional; Region: PRK15369
1171376001957	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376001958	active site
1171376001959	phosphorylation site [posttranslational modification]
1171376001960	intermolecular recognition site; other site
1171376001961	dimerization interface [polypeptide binding]; other site
1171376001962	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376001963	DNA binding residues [nucleotide binding]
1171376001964	dimerization interface [polypeptide binding]; other site
1171376001965	two component system sensor kinase SsrA; Provisional; Region: PRK15347
1171376001966	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376001967	dimerization interface [polypeptide binding]; other site
1171376001968	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376001969	dimer interface [polypeptide binding]; other site
1171376001970	phosphorylation site [posttranslational modification]
1171376001971	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376001972	ATP binding site [chemical binding]; other site
1171376001973	Mg2+ binding site [ion binding]; other site
1171376001974	G-X-G motif; other site
1171376001975	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376001976	active site
1171376001977	phosphorylation site [posttranslational modification]
1171376001978	intermolecular recognition site; other site
1171376001979	dimerization interface [polypeptide binding]; other site
1171376001980	pathogenicity island chaperone protein SpiC; Provisional; Region: PRK15368
1171376001981	outer membrane secretin SsaC; Provisional; Region: PRK15346
1171376001982	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1171376001983	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1171376001984	type III secretion system protein SsaD; Provisional; Region: PRK15367
1171376001985	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
1171376001986	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
1171376001987	type III secretion system chaperone SseA; Provisional; Region: PRK15365
1171376001988	pathogenicity island 2 effector protein SseB; Provisional; Region: PRK15364
1171376001989	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
1171376001990	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
1171376001991	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
1171376001992	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
1171376001993	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
1171376001994	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1171376001995	TPR motif; other site
1171376001996	binding surface
1171376001997	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
1171376001998	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
1171376001999	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
1171376002000	type III secretion system protein SsaH; Provisional; Region: PRK15356
1171376002001	type III secretion system protein SsaI; Provisional; Region: PRK15355
1171376002002	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
1171376002003	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
1171376002004	type III secretion system protein SsaK; Provisional; Region: PRK15354
1171376002005	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
1171376002006	type III secretion system protein SsaL; Provisional; Region: PRK15345
1171376002007	HrpJ-like domain; Region: HrpJ; pfam07201
1171376002008	TyeA; Region: TyeA; cl07611
1171376002009	type III secretion system protein SsaM; Provisional; Region: PRK15353
1171376002010	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
1171376002011	FHIPEP family; Region: FHIPEP; pfam00771
1171376002012	type III secretion system ATPase SsaN; Validated; Region: PRK07594
1171376002013	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1171376002014	Walker A motif; other site
1171376002015	ATP binding site [chemical binding]; other site
1171376002016	Walker B motif; other site
1171376002017	type III secretion system protein SsaO; Provisional; Region: PRK15352
1171376002018	type III secretion system protein SsaP; Provisional; Region: PRK15351
1171376002019	type III secretion system protein SsaQ; Validated; Region: PRK08035
1171376002020	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437
1171376002021	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1171376002022	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
1171376002023	type III secretion system protein SsaS; Provisional; Region: PRK15350
1171376002024	type III secretion system protein SsaT; Provisional; Region: PRK15349
1171376002025	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
1171376002026	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1171376002027	multidrug efflux protein; Reviewed; Region: PRK01766
1171376002028	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1171376002029	cation binding site [ion binding]; other site
1171376002030	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1171376002031	Lumazine binding domain; Region: Lum_binding; pfam00677
1171376002032	Lumazine binding domain; Region: Lum_binding; pfam00677
1171376002033	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1171376002034	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376002035	S-adenosylmethionine binding site [chemical binding]; other site
1171376002036	putative transporter; Provisional; Region: PRK11043
1171376002037	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376002038	putative substrate translocation pore; other site
1171376002039	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1171376002040	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376002041	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376002042	dimerization interface [polypeptide binding]; other site
1171376002043	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1171376002044	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376002045	DNA binding site [nucleotide binding]
1171376002046	domain linker motif; other site
1171376002047	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1171376002048	dimerization interface [polypeptide binding]; other site
1171376002049	ligand binding site [chemical binding]; other site
1171376002050	superoxide dismutase; Provisional; Region: PRK10543
1171376002051	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1171376002052	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1171376002053	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1171376002054	NlpC/P60 family; Region: NLPC_P60; pfam00877
1171376002055	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1171376002056	putative GSH binding site [chemical binding]; other site
1171376002057	catalytic residues [active]
1171376002058	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1171376002059	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1171376002060	dimer interface [polypeptide binding]; other site
1171376002061	catalytic site [active]
1171376002062	putative active site [active]
1171376002063	putative substrate binding site [chemical binding]; other site
1171376002064	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1171376002065	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1171376002066	dimer interface [polypeptide binding]; other site
1171376002067	active site
1171376002068	metal binding site [ion binding]; metal-binding site
1171376002069	glutathione binding site [chemical binding]; other site
1171376002070	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1171376002071	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1171376002072	FMN binding site [chemical binding]; other site
1171376002073	active site
1171376002074	substrate binding site [chemical binding]; other site
1171376002075	catalytic residue [active]
1171376002076	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1171376002077	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376002078	Predicted Fe-S protein [General function prediction only]; Region: COG3313
1171376002079	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1171376002080	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1171376002081	active site
1171376002082	catalytic tetrad [active]
1171376002083	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1171376002084	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1171376002085	E-class dimer interface [polypeptide binding]; other site
1171376002086	P-class dimer interface [polypeptide binding]; other site
1171376002087	active site
1171376002088	Cu2+ binding site [ion binding]; other site
1171376002089	Zn2+ binding site [ion binding]; other site
1171376002090	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1171376002091	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1171376002092	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1171376002093	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1171376002094	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376002095	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1171376002096	transcriptional regulator SlyA; Provisional; Region: PRK03573
1171376002097	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1171376002098	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1171376002099	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
1171376002100	lysozyme inhibitor; Provisional; Region: PRK11372
1171376002101	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1171376002102	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1171376002103	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1171376002104	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1171376002105	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1171376002106	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1171376002107	active site
1171376002108	HIGH motif; other site
1171376002109	dimer interface [polypeptide binding]; other site
1171376002110	KMSKS motif; other site
1171376002111	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1171376002112	RNA binding surface [nucleotide binding]; other site
1171376002113	pyridoxamine kinase; Validated; Region: PRK05756
1171376002114	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1171376002115	dimer interface [polypeptide binding]; other site
1171376002116	pyridoxal binding site [chemical binding]; other site
1171376002117	ATP binding site [chemical binding]; other site
1171376002118	glutathionine S-transferase; Provisional; Region: PRK10542
1171376002119	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1171376002120	C-terminal domain interface [polypeptide binding]; other site
1171376002121	GSH binding site (G-site) [chemical binding]; other site
1171376002122	dimer interface [polypeptide binding]; other site
1171376002123	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1171376002124	dimer interface [polypeptide binding]; other site
1171376002125	N-terminal domain interface [polypeptide binding]; other site
1171376002126	substrate binding pocket (H-site) [chemical binding]; other site
1171376002127	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1171376002128	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376002129	putative substrate translocation pore; other site
1171376002130	POT family; Region: PTR2; pfam00854
1171376002131	endonuclease III; Provisional; Region: PRK10702
1171376002132	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1171376002133	minor groove reading motif; other site
1171376002134	helix-hairpin-helix signature motif; other site
1171376002135	substrate binding pocket [chemical binding]; other site
1171376002136	active site
1171376002137	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1171376002138	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1171376002139	electron transport complex protein RnfG; Validated; Region: PRK01908
1171376002140	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1171376002141	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1171376002142	SLBB domain; Region: SLBB; pfam10531
1171376002143	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1171376002144	electron transport complex protein RnfB; Provisional; Region: PRK05113
1171376002145	Putative Fe-S cluster; Region: FeS; cl17515
1171376002146	4Fe-4S binding domain; Region: Fer4; pfam00037
1171376002147	electron transport complex protein RsxA; Provisional; Region: PRK05151
1171376002148	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1171376002149	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1171376002150	putative oxidoreductase; Provisional; Region: PRK11579
1171376002151	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1171376002152	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1171376002153	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1171376002154	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1171376002155	active site
1171376002156	purine riboside binding site [chemical binding]; other site
1171376002157	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
1171376002158	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1171376002159	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1171376002160	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1171376002161	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1171376002162	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1171376002163	fumarate hydratase; Provisional; Region: PRK15389
1171376002164	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1171376002165	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1171376002166	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1171376002167	Class II fumarases; Region: Fumarase_classII; cd01362
1171376002168	active site
1171376002169	tetramer interface [polypeptide binding]; other site
1171376002170	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1171376002171	sensor protein RstB; Provisional; Region: PRK10604
1171376002172	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376002173	dimerization interface [polypeptide binding]; other site
1171376002174	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376002175	dimer interface [polypeptide binding]; other site
1171376002176	phosphorylation site [posttranslational modification]
1171376002177	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376002178	ATP binding site [chemical binding]; other site
1171376002179	Mg2+ binding site [ion binding]; other site
1171376002180	G-X-G motif; other site
1171376002181	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1171376002182	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1171376002183	active site
1171376002184	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1171376002185	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1171376002186	trimer interface [polypeptide binding]; other site
1171376002187	eyelet of channel; other site
1171376002188	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1171376002189	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376002190	active site
1171376002191	phosphorylation site [posttranslational modification]
1171376002192	intermolecular recognition site; other site
1171376002193	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376002194	DNA binding site [nucleotide binding]
1171376002195	GlpM protein; Region: GlpM; pfam06942
1171376002196	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1171376002197	Spore germination protein; Region: Spore_permease; cl17796
1171376002198	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1171376002199	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1171376002200	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1171376002201	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1171376002202	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1171376002203	ligand binding site [chemical binding]; other site
1171376002204	homodimer interface [polypeptide binding]; other site
1171376002205	NAD(P) binding site [chemical binding]; other site
1171376002206	trimer interface B [polypeptide binding]; other site
1171376002207	trimer interface A [polypeptide binding]; other site
1171376002208	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1171376002209	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1171376002210	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1171376002211	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1171376002212	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1171376002213	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1171376002214	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1171376002215	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1171376002216	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1171376002217	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376002218	putative substrate translocation pore; other site
1171376002219	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1171376002220	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376002221	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1171376002222	dimerization interface [polypeptide binding]; other site
1171376002223	substrate binding pocket [chemical binding]; other site
1171376002224	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1171376002225	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1171376002226	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1171376002227	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1171376002228	AAA domain; Region: AAA_26; pfam13500
1171376002229	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1171376002230	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1171376002231	Cl- selectivity filter; other site
1171376002232	Cl- binding residues [ion binding]; other site
1171376002233	pore gating glutamate residue; other site
1171376002234	dimer interface [polypeptide binding]; other site
1171376002235	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1171376002236	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1171376002237	Walker A/P-loop; other site
1171376002238	ATP binding site [chemical binding]; other site
1171376002239	Q-loop/lid; other site
1171376002240	ABC transporter signature motif; other site
1171376002241	Walker B; other site
1171376002242	D-loop; other site
1171376002243	H-loop/switch region; other site
1171376002244	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
1171376002245	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376002246	dimer interface [polypeptide binding]; other site
1171376002247	conserved gate region; other site
1171376002248	ABC-ATPase subunit interface; other site
1171376002249	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1171376002250	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376002251	dimer interface [polypeptide binding]; other site
1171376002252	conserved gate region; other site
1171376002253	putative PBP binding loops; other site
1171376002254	ABC-ATPase subunit interface; other site
1171376002255	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1171376002256	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1171376002257	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1171376002258	4Fe-4S binding domain; Region: Fer4; pfam00037
1171376002259	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1171376002260	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1171376002261	putative [Fe4-S4] binding site [ion binding]; other site
1171376002262	putative molybdopterin cofactor binding site [chemical binding]; other site
1171376002263	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1171376002264	putative molybdopterin cofactor binding site; other site
1171376002265	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1171376002266	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1171376002267	putative [Fe4-S4] binding site [ion binding]; other site
1171376002268	putative molybdopterin cofactor binding site [chemical binding]; other site
1171376002269	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1171376002270	putative molybdopterin cofactor binding site; other site
1171376002271	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1171376002272	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
1171376002273	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1171376002274	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376002275	Coenzyme A binding pocket [chemical binding]; other site
1171376002276	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1171376002277	hypothetical protein; Provisional; Region: PRK13659
1171376002278	hypothetical protein; Provisional; Region: PRK02237
1171376002279	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1171376002280	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1171376002281	putative active site pocket [active]
1171376002282	putative metal binding site [ion binding]; other site
1171376002283	putative oxidoreductase; Provisional; Region: PRK10083
1171376002284	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1171376002285	putative NAD(P) binding site [chemical binding]; other site
1171376002286	catalytic Zn binding site [ion binding]; other site
1171376002287	structural Zn binding site [ion binding]; other site
1171376002288	potential frameshift: common BLAST hit: gi|409250183|ref|YP_006885994.1| putative inner membrane metabolite transport protein ydfJ
1171376002289	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1171376002290	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1171376002291	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1171376002292	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
1171376002293	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1171376002294	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376002295	DNA-binding site [nucleotide binding]; DNA binding site
1171376002296	FCD domain; Region: FCD; pfam07729
1171376002297	malonic semialdehyde reductase; Provisional; Region: PRK10538
1171376002298	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1171376002299	putative NAD(P) binding site [chemical binding]; other site
1171376002300	homodimer interface [polypeptide binding]; other site
1171376002301	homotetramer interface [polypeptide binding]; other site
1171376002302	active site
1171376002303	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1171376002304	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1171376002305	active site
1171376002306	Zn binding site [ion binding]; other site
1171376002307	hypothetical protein; Validated; Region: PRK03657
1171376002308	hypothetical protein; Provisional; Region: PRK10053
1171376002309	putative transporter; Provisional; Region: PRK10054
1171376002310	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376002311	putative substrate translocation pore; other site
1171376002312	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1171376002313	EamA-like transporter family; Region: EamA; pfam00892
1171376002314	MarB protein; Region: MarB; pfam13999
1171376002315	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
1171376002316	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376002317	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376002318	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
1171376002319	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1171376002320	inner membrane protein; Provisional; Region: PRK10995
1171376002321	putative arabinose transporter; Provisional; Region: PRK03545
1171376002322	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376002323	putative substrate translocation pore; other site
1171376002324	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376002325	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376002326	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1171376002327	putative dimerization interface [polypeptide binding]; other site
1171376002328	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
1171376002329	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1171376002330	NAD(P) binding site [chemical binding]; other site
1171376002331	catalytic residues [active]
1171376002332	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1171376002333	glutaminase; Provisional; Region: PRK00971
1171376002334	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1171376002335	Predicted membrane protein [Function unknown]; Region: COG3781
1171376002336	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1171376002337	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1171376002338	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1171376002339	trimer interface [polypeptide binding]; other site
1171376002340	eyelet of channel; other site
1171376002341	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1171376002342	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1171376002343	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
1171376002344	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1171376002345	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1171376002346	Rubredoxin [Energy production and conversion]; Region: COG1773
1171376002347	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1171376002348	iron binding site [ion binding]; other site
1171376002349	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1171376002350	HupF/HypC family; Region: HupF_HypC; cl00394
1171376002351	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1171376002352	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1171376002353	putative substrate-binding site; other site
1171376002354	nickel binding site [ion binding]; other site
1171376002355	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
1171376002356	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1171376002357	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1171376002358	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
1171376002359	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1171376002360	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1171376002361	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
1171376002362	active site
1171376002363	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1171376002364	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376002365	DNA-binding site [nucleotide binding]; DNA binding site
1171376002366	FCD domain; Region: FCD; pfam07729
1171376002367	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1171376002368	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1171376002369	putative NAD(P) binding site [chemical binding]; other site
1171376002370	catalytic Zn binding site [ion binding]; other site
1171376002371	structural Zn binding site [ion binding]; other site
1171376002372	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376002373	D-galactonate transporter; Region: 2A0114; TIGR00893
1171376002374	putative substrate translocation pore; other site
1171376002375	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
1171376002376	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376002377	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1171376002378	putative substrate translocation pore; other site
1171376002379	hypothetical protein; Provisional; Region: PRK06184
1171376002380	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1171376002381	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1171376002382	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1171376002383	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1171376002384	putative DNA binding site [nucleotide binding]; other site
1171376002385	putative Zn2+ binding site [ion binding]; other site
1171376002386	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
1171376002387	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1171376002388	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
1171376002389	homotrimer interaction site [polypeptide binding]; other site
1171376002390	putative active site [active]
1171376002391	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1171376002392	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
1171376002393	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1171376002394	Winged helix-turn helix; Region: HTH_29; pfam13551
1171376002395	Helix-turn-helix domain; Region: HTH_28; pfam13518
1171376002396	Homeodomain-like domain; Region: HTH_32; pfam13565
1171376002397	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1171376002398	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376002399	DNA binding site [nucleotide binding]
1171376002400	domain linker motif; other site
1171376002401	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1171376002402	dimerization interface (closed form) [polypeptide binding]; other site
1171376002403	ligand binding site [chemical binding]; other site
1171376002404	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
1171376002405	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1171376002406	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376002407	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376002408	homodimer interface [polypeptide binding]; other site
1171376002409	catalytic residue [active]
1171376002410	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1171376002411	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1171376002412	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1171376002413	active site
1171376002414	catalytic site [active]
1171376002415	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
1171376002416	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1171376002417	active site
1171376002418	catalytic site [active]
1171376002419	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
1171376002420	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
1171376002421	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
1171376002422	catalytic site [active]
1171376002423	active site
1171376002424	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1171376002425	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
1171376002426	acid-resistance protein; Provisional; Region: hdeB; PRK11566
1171376002427	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1171376002428	biofilm-dependent modulation protein; Provisional; Region: PRK11436
1171376002429	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
1171376002430	malate dehydrogenase; Provisional; Region: PRK13529
1171376002431	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1171376002432	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1171376002433	NAD(P) binding site [chemical binding]; other site
1171376002434	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1171376002435	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1171376002436	NAD binding site [chemical binding]; other site
1171376002437	substrate binding site [chemical binding]; other site
1171376002438	catalytic Zn binding site [ion binding]; other site
1171376002439	tetramer interface [polypeptide binding]; other site
1171376002440	structural Zn binding site [ion binding]; other site
1171376002441	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
1171376002442	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1171376002443	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1171376002444	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1171376002445	potential frameshift: common BLAST hit: gi|379700741|ref|YP_005242469.1| formate dehydrogenase-N subunit alpha
1171376002446	aromatic amino acid exporter; Provisional; Region: PRK11689
1171376002447	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1171376002448	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1171376002449	trimer interface [polypeptide binding]; other site
1171376002450	eyelet of channel; other site
1171376002451	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1171376002452	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1171376002453	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376002454	putative substrate translocation pore; other site
1171376002455	TetR family transcriptional regulator; Provisional; Region: PRK14996
1171376002456	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376002457	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1171376002458	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1171376002459	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1171376002460	[4Fe-4S] binding site [ion binding]; other site
1171376002461	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1171376002462	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1171376002463	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1171376002464	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1171376002465	molybdopterin cofactor binding site; other site
1171376002466	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1171376002467	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
1171376002468	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1171376002469	hypothetical protein; Provisional; Region: PRK10281
1171376002470	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
1171376002471	L-asparagine permease; Provisional; Region: PRK15049
1171376002472	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1171376002473	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1171376002474	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1171376002475	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1171376002476	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1171376002477	N-terminal plug; other site
1171376002478	ligand-binding site [chemical binding]; other site
1171376002479	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
1171376002480	DNA-binding site [nucleotide binding]; DNA binding site
1171376002481	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1171376002482	FCD domain; Region: FCD; pfam07729
1171376002483	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1171376002484	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1171376002485	NAD(P) binding site [chemical binding]; other site
1171376002486	substrate binding site [chemical binding]; other site
1171376002487	dimer interface [polypeptide binding]; other site
1171376002488	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1171376002489	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1171376002490	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1171376002491	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1171376002492	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
1171376002493	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
1171376002494	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1171376002495	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
1171376002496	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
1171376002497	tetrameric interface [polypeptide binding]; other site
1171376002498	NAD binding site [chemical binding]; other site
1171376002499	catalytic residues [active]
1171376002500	substrate binding site [chemical binding]; other site
1171376002501	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1171376002502	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376002503	DNA-binding site [nucleotide binding]; DNA binding site
1171376002504	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376002505	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376002506	homodimer interface [polypeptide binding]; other site
1171376002507	catalytic residue [active]
1171376002508	D-alanyl-D-alanine dipeptidase [Cell envelope biogenesis, outer membrane]; Region: DdpX; COG2173
1171376002509	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
1171376002510	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
1171376002511	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1171376002512	Peptidase family U32; Region: Peptidase_U32; pfam01136
1171376002513	Collagenase; Region: DUF3656; pfam12392
1171376002514	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1171376002515	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376002516	non-specific DNA binding site [nucleotide binding]; other site
1171376002517	salt bridge; other site
1171376002518	sequence-specific DNA binding site [nucleotide binding]; other site
1171376002519	Cupin domain; Region: Cupin_2; pfam07883
1171376002520	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
1171376002521	benzoate transporter; Region: benE; TIGR00843
1171376002522	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1171376002523	tellurite resistance protein TehB; Provisional; Region: PRK11207
1171376002524	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376002525	S-adenosylmethionine binding site [chemical binding]; other site
1171376002526	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1171376002527	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1171376002528	gating phenylalanine in ion channel; other site
1171376002529	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1171376002530	putative trimer interface [polypeptide binding]; other site
1171376002531	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1171376002532	putative trimer interface [polypeptide binding]; other site
1171376002533	putative CoA binding site [chemical binding]; other site
1171376002534	putative CoA binding site [chemical binding]; other site
1171376002535	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1171376002536	putative trimer interface [polypeptide binding]; other site
1171376002537	putative CoA binding site [chemical binding]; other site
1171376002538	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1171376002539	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376002540	Coenzyme A binding pocket [chemical binding]; other site
1171376002541	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1171376002542	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1171376002543	oligomer interface [polypeptide binding]; other site
1171376002544	active site
1171376002545	metal binding site [ion binding]; metal-binding site
1171376002546	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1171376002547	active site
1171376002548	P-loop; other site
1171376002549	phosphorylation site [posttranslational modification]
1171376002550	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1171376002551	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
1171376002552	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
1171376002553	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376002554	active site
1171376002555	phosphorylation site [posttranslational modification]
1171376002556	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1171376002557	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1171376002558	substrate binding site [chemical binding]; other site
1171376002559	hexamer interface [polypeptide binding]; other site
1171376002560	metal binding site [ion binding]; metal-binding site
1171376002561	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1171376002562	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1171376002563	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376002564	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1171376002565	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376002566	Coenzyme A binding pocket [chemical binding]; other site
1171376002567	L-lactate oxidase; Region: L_lactate_ox; TIGR02708
1171376002568	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
1171376002569	teramer interface [polypeptide binding]; other site
1171376002570	active site
1171376002571	FMN binding site [chemical binding]; other site
1171376002572	catalytic residues [active]
1171376002573	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1171376002574	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1171376002575	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1171376002576	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1171376002577	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1171376002578	substrate binding pocket [chemical binding]; other site
1171376002579	catalytic triad [active]
1171376002580	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1171376002581	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1171376002582	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1171376002583	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376002584	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376002585	dimerization interface [polypeptide binding]; other site
1171376002586	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1171376002587	dimer interface [polypeptide binding]; other site
1171376002588	ligand binding site [chemical binding]; other site
1171376002589	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1171376002590	HAMP domain; Region: HAMP; pfam00672
1171376002591	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1171376002592	dimer interface [polypeptide binding]; other site
1171376002593	putative CheW interface [polypeptide binding]; other site
1171376002594	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1171376002595	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1171376002596	substrate binding site [chemical binding]; other site
1171376002597	catalytic Zn binding site [ion binding]; other site
1171376002598	NAD binding site [chemical binding]; other site
1171376002599	structural Zn binding site [ion binding]; other site
1171376002600	dimer interface [polypeptide binding]; other site
1171376002601	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1171376002602	putative metal binding site [ion binding]; other site
1171376002603	putative homodimer interface [polypeptide binding]; other site
1171376002604	putative homotetramer interface [polypeptide binding]; other site
1171376002605	putative homodimer-homodimer interface [polypeptide binding]; other site
1171376002606	putative allosteric switch controlling residues; other site
1171376002607	Sif protein; Region: Sif; cl11505
1171376002608	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1171376002609	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
1171376002610	active site
1171376002611	catalytic triad [active]
1171376002612	oxyanion hole [active]
1171376002613	Predicted membrane protein [Function unknown]; Region: COG3326
1171376002614	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376002615	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1171376002616	substrate binding pocket [chemical binding]; other site
1171376002617	membrane-bound complex binding site; other site
1171376002618	hinge residues; other site
1171376002619	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1171376002620	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376002621	dimer interface [polypeptide binding]; other site
1171376002622	conserved gate region; other site
1171376002623	putative PBP binding loops; other site
1171376002624	ABC-ATPase subunit interface; other site
1171376002625	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1171376002626	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376002627	Walker A/P-loop; other site
1171376002628	ATP binding site [chemical binding]; other site
1171376002629	Q-loop/lid; other site
1171376002630	ABC transporter signature motif; other site
1171376002631	Walker B; other site
1171376002632	D-loop; other site
1171376002633	H-loop/switch region; other site
1171376002634	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1171376002635	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376002636	dimer interface [polypeptide binding]; other site
1171376002637	conserved gate region; other site
1171376002638	putative PBP binding loops; other site
1171376002639	ABC-ATPase subunit interface; other site
1171376002640	Predicted membrane protein [Function unknown]; Region: COG5305
1171376002641	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1171376002642	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376002643	S-adenosylmethionine binding site [chemical binding]; other site
1171376002644	cytochrome b561; Provisional; Region: PRK11513
1171376002645	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1171376002646	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1171376002647	putative active site [active]
1171376002648	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1171376002649	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1171376002650	ATP binding site [chemical binding]; other site
1171376002651	putative Mg++ binding site [ion binding]; other site
1171376002652	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376002653	nucleotide binding region [chemical binding]; other site
1171376002654	ATP-binding site [chemical binding]; other site
1171376002655	Helicase associated domain (HA2); Region: HA2; pfam04408
1171376002656	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1171376002657	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1171376002658	azoreductase; Reviewed; Region: PRK00170
1171376002659	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1171376002660	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1171376002661	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1171376002662	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1171376002663	hypothetical protein; Provisional; Region: PRK10695
1171376002664	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1171376002665	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1171376002666	putative ligand binding site [chemical binding]; other site
1171376002667	putative NAD binding site [chemical binding]; other site
1171376002668	catalytic site [active]
1171376002669	heat-inducible protein; Provisional; Region: PRK10449
1171376002670	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1171376002671	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1171376002672	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1171376002673	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1171376002674	dimer interface [polypeptide binding]; other site
1171376002675	PYR/PP interface [polypeptide binding]; other site
1171376002676	TPP binding site [chemical binding]; other site
1171376002677	substrate binding site [chemical binding]; other site
1171376002678	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1171376002679	Domain of unknown function; Region: EKR; smart00890
1171376002680	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1171376002681	4Fe-4S binding domain; Region: Fer4; pfam00037
1171376002682	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1171376002683	TPP-binding site [chemical binding]; other site
1171376002684	dimer interface [polypeptide binding]; other site
1171376002685	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1171376002686	Ligand Binding Site [chemical binding]; other site
1171376002687	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1171376002688	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1171376002689	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1171376002690	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1171376002691	Ligand Binding Site [chemical binding]; other site
1171376002692	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1171376002693	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1171376002694	ATP binding site [chemical binding]; other site
1171376002695	Mg++ binding site [ion binding]; other site
1171376002696	motif III; other site
1171376002697	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376002698	nucleotide binding region [chemical binding]; other site
1171376002699	ATP-binding site [chemical binding]; other site
1171376002700	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1171376002701	putative RNA binding site [nucleotide binding]; other site
1171376002702	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1171376002703	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1171376002704	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1171376002705	Cl binding site [ion binding]; other site
1171376002706	oligomer interface [polypeptide binding]; other site
1171376002707	HAMP domain; Region: HAMP; pfam00672
1171376002708	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1171376002709	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1171376002710	dimer interface [polypeptide binding]; other site
1171376002711	putative CheW interface [polypeptide binding]; other site
1171376002712	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1171376002713	Smr domain; Region: Smr; pfam01713
1171376002714	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1171376002715	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1171376002716	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1171376002717	DNA binding site [nucleotide binding]
1171376002718	active site
1171376002719	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1171376002720	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1171376002721	ligand binding site [chemical binding]; other site
1171376002722	flexible hinge region; other site
1171376002723	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1171376002724	putative switch regulator; other site
1171376002725	non-specific DNA interactions [nucleotide binding]; other site
1171376002726	DNA binding site [nucleotide binding]
1171376002727	sequence specific DNA binding site [nucleotide binding]; other site
1171376002728	putative cAMP binding site [chemical binding]; other site
1171376002729	universal stress protein UspE; Provisional; Region: PRK11175
1171376002730	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1171376002731	Ligand Binding Site [chemical binding]; other site
1171376002732	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1171376002733	Ligand Binding Site [chemical binding]; other site
1171376002734	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1171376002735	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1171376002736	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1171376002737	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1171376002738	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376002739	non-specific DNA binding site [nucleotide binding]; other site
1171376002740	salt bridge; other site
1171376002741	sequence-specific DNA binding site [nucleotide binding]; other site
1171376002742	Cupin domain; Region: Cupin_2; pfam07883
1171376002743	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1171376002744	B3/4 domain; Region: B3_4; pfam03483
1171376002745	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: Tpx; COG2077
1171376002746	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1171376002747	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1171376002748	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376002749	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1171376002750	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1171376002751	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1171376002752	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376002753	oxidoreductase; Provisional; Region: PRK12742
1171376002754	classical (c) SDRs; Region: SDR_c; cd05233
1171376002755	NAD(P) binding site [chemical binding]; other site
1171376002756	active site
1171376002757	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1171376002758	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1171376002759	active site
1171376002760	catalytic tetrad [active]
1171376002761	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376002762	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376002763	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1171376002764	putative effector binding pocket; other site
1171376002765	putative dimerization interface [polypeptide binding]; other site
1171376002766	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
1171376002767	NmrA-like family; Region: NmrA; pfam05368
1171376002768	NAD(P) binding site [chemical binding]; other site
1171376002769	active site lysine
1171376002770	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1171376002771	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1171376002772	peptide binding site [polypeptide binding]; other site
1171376002773	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
1171376002774	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
1171376002775	putative active site [active]
1171376002776	Zn binding site [ion binding]; other site
1171376002777	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1171376002778	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1171376002779	active site
1171376002780	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1171376002781	dimer interface [polypeptide binding]; other site
1171376002782	catalytic triad [active]
1171376002783	peroxidatic and resolving cysteines [active]
1171376002784	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1171376002785	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1171376002786	putative aromatic amino acid binding site; other site
1171376002787	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376002788	Walker A motif; other site
1171376002789	ATP binding site [chemical binding]; other site
1171376002790	Walker B motif; other site
1171376002791	arginine finger; other site
1171376002792	hypothetical protein; Provisional; Region: PRK05415
1171376002793	TIGR01620 family protein; Region: hyp_HI0043
1171376002794	Predicted ATPase [General function prediction only]; Region: COG3106
1171376002795	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1171376002796	active site residue [active]
1171376002797	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1171376002798	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1171376002799	phage shock protein C; Region: phageshock_pspC; TIGR02978
1171376002800	phage shock protein B; Provisional; Region: pspB; PRK09458
1171376002801	phage shock protein PspA; Provisional; Region: PRK10698
1171376002802	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1171376002803	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376002804	Walker A motif; other site
1171376002805	ATP binding site [chemical binding]; other site
1171376002806	Walker B motif; other site
1171376002807	arginine finger; other site
1171376002808	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1171376002809	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1171376002810	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1171376002811	peptide binding site [polypeptide binding]; other site
1171376002812	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1171376002813	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376002814	dimer interface [polypeptide binding]; other site
1171376002815	conserved gate region; other site
1171376002816	putative PBP binding loops; other site
1171376002817	ABC-ATPase subunit interface; other site
1171376002818	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1171376002819	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1171376002820	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376002821	dimer interface [polypeptide binding]; other site
1171376002822	conserved gate region; other site
1171376002823	putative PBP binding loops; other site
1171376002824	ABC-ATPase subunit interface; other site
1171376002825	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1171376002826	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1171376002827	Walker A/P-loop; other site
1171376002828	ATP binding site [chemical binding]; other site
1171376002829	Q-loop/lid; other site
1171376002830	ABC transporter signature motif; other site
1171376002831	Walker B; other site
1171376002832	D-loop; other site
1171376002833	H-loop/switch region; other site
1171376002834	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1171376002835	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1171376002836	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1171376002837	Walker A/P-loop; other site
1171376002838	ATP binding site [chemical binding]; other site
1171376002839	Q-loop/lid; other site
1171376002840	ABC transporter signature motif; other site
1171376002841	Walker B; other site
1171376002842	D-loop; other site
1171376002843	H-loop/switch region; other site
1171376002844	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1171376002845	Protein kinase domain; Region: Pkinase; pfam00069
1171376002846	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1171376002847	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1171376002848	NAD binding site [chemical binding]; other site
1171376002849	homotetramer interface [polypeptide binding]; other site
1171376002850	homodimer interface [polypeptide binding]; other site
1171376002851	substrate binding site [chemical binding]; other site
1171376002852	active site
1171376002853	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
1171376002854	exoribonuclease II; Provisional; Region: PRK05054
1171376002855	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1171376002856	RNB domain; Region: RNB; pfam00773
1171376002857	S1 RNA binding domain; Region: S1; pfam00575
1171376002858	RNase II stability modulator; Provisional; Region: PRK10060
1171376002859	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1171376002860	putative active site [active]
1171376002861	heme pocket [chemical binding]; other site
1171376002862	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376002863	metal binding site [ion binding]; metal-binding site
1171376002864	active site
1171376002865	I-site; other site
1171376002866	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376002867	hypothetical protein; Provisional; Region: PRK13658
1171376002868	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1171376002869	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1171376002870	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376002871	lipoprotein; Provisional; Region: PRK10540
1171376002872	translation initiation factor Sui1; Validated; Region: PRK06824
1171376002873	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1171376002874	putative rRNA binding site [nucleotide binding]; other site
1171376002875	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1171376002876	active site
1171376002877	dimer interface [polypeptide binding]; other site
1171376002878	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1171376002879	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1171376002880	binding surface
1171376002881	TPR motif; other site
1171376002882	Predicted membrane protein [Function unknown]; Region: COG3771
1171376002883	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1171376002884	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1171376002885	active site
1171376002886	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1171376002887	dimerization interface [polypeptide binding]; other site
1171376002888	active site
1171376002889	aconitate hydratase; Validated; Region: PRK09277
1171376002890	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1171376002891	substrate binding site [chemical binding]; other site
1171376002892	ligand binding site [chemical binding]; other site
1171376002893	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1171376002894	substrate binding site [chemical binding]; other site
1171376002895	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1171376002896	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376002897	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1171376002898	substrate binding site [chemical binding]; other site
1171376002899	putative dimerization interface [polypeptide binding]; other site
1171376002900	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1171376002901	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1171376002902	active site
1171376002903	interdomain interaction site; other site
1171376002904	putative metal-binding site [ion binding]; other site
1171376002905	nucleotide binding site [chemical binding]; other site
1171376002906	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1171376002907	domain I; other site
1171376002908	DNA binding groove [nucleotide binding]
1171376002909	phosphate binding site [ion binding]; other site
1171376002910	domain II; other site
1171376002911	domain III; other site
1171376002912	nucleotide binding site [chemical binding]; other site
1171376002913	catalytic site [active]
1171376002914	domain IV; other site
1171376002915	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1171376002916	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1171376002917	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1171376002918	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1171376002919	hypothetical protein; Provisional; Region: PRK11037
1171376002920	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1171376002921	putative inner membrane peptidase; Provisional; Region: PRK11778
1171376002922	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1171376002923	tandem repeat interface [polypeptide binding]; other site
1171376002924	oligomer interface [polypeptide binding]; other site
1171376002925	active site residues [active]
1171376002926	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1171376002927	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1171376002928	NADP binding site [chemical binding]; other site
1171376002929	homodimer interface [polypeptide binding]; other site
1171376002930	active site
1171376002931	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1171376002932	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
1171376002933	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1171376002934	homodimer interface [polypeptide binding]; other site
1171376002935	Walker A motif; other site
1171376002936	ATP binding site [chemical binding]; other site
1171376002937	hydroxycobalamin binding site [chemical binding]; other site
1171376002938	Walker B motif; other site
1171376002939	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1171376002940	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1171376002941	RNA binding surface [nucleotide binding]; other site
1171376002942	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1171376002943	probable active site [active]
1171376002944	hypothetical protein; Provisional; Region: PRK11630
1171376002945	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1171376002946	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1171376002947	active site
1171376002948	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1171376002949	anthranilate synthase component I; Provisional; Region: PRK13564
1171376002950	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1171376002951	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1171376002952	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
1171376002953	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1171376002954	glutamine binding [chemical binding]; other site
1171376002955	catalytic triad [active]
1171376002956	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1171376002957	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1171376002958	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1171376002959	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1171376002960	active site
1171376002961	ribulose/triose binding site [chemical binding]; other site
1171376002962	phosphate binding site [ion binding]; other site
1171376002963	substrate (anthranilate) binding pocket [chemical binding]; other site
1171376002964	product (indole) binding pocket [chemical binding]; other site
1171376002965	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1171376002966	active site
1171376002967	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1171376002968	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1171376002969	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376002970	catalytic residue [active]
1171376002971	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1171376002972	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1171376002973	substrate binding site [chemical binding]; other site
1171376002974	active site
1171376002975	catalytic residues [active]
1171376002976	heterodimer interface [polypeptide binding]; other site
1171376002977	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
1171376002978	dimerization interface [polypeptide binding]; other site
1171376002979	metal binding site [ion binding]; metal-binding site
1171376002980	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1171376002981	dinuclear metal binding motif [ion binding]; other site
1171376002982	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1171376002983	dimanganese center [ion binding]; other site
1171376002984	outer membrane protein W; Provisional; Region: PRK10959
1171376002985	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1171376002986	hypothetical protein; Provisional; Region: PRK02868
1171376002987	intracellular septation protein A; Reviewed; Region: PRK00259
1171376002988	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1171376002989	transport protein TonB; Provisional; Region: PRK10819
1171376002990	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1171376002991	YciI-like protein; Reviewed; Region: PRK11370
1171376002992	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1171376002993	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1171376002994	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1171376002995	putative active site [active]
1171376002996	catalytic site [active]
1171376002997	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1171376002998	putative active site [active]
1171376002999	catalytic site [active]
1171376003000	dsDNA-mimic protein; Reviewed; Region: PRK05094
1171376003001	Ion transport protein; Region: Ion_trans; pfam00520
1171376003002	Ion channel; Region: Ion_trans_2; pfam07885
1171376003003	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1171376003004	Double zinc ribbon; Region: DZR; pfam12773
1171376003005	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1171376003006	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1171376003007	Walker A/P-loop; other site
1171376003008	ATP binding site [chemical binding]; other site
1171376003009	Q-loop/lid; other site
1171376003010	ABC transporter signature motif; other site
1171376003011	Walker B; other site
1171376003012	D-loop; other site
1171376003013	H-loop/switch region; other site
1171376003014	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1171376003015	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1171376003016	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1171376003017	Walker A/P-loop; other site
1171376003018	ATP binding site [chemical binding]; other site
1171376003019	Q-loop/lid; other site
1171376003020	ABC transporter signature motif; other site
1171376003021	Walker B; other site
1171376003022	D-loop; other site
1171376003023	H-loop/switch region; other site
1171376003024	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1171376003025	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1171376003026	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1171376003027	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376003028	dimer interface [polypeptide binding]; other site
1171376003029	conserved gate region; other site
1171376003030	ABC-ATPase subunit interface; other site
1171376003031	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1171376003032	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376003033	dimer interface [polypeptide binding]; other site
1171376003034	conserved gate region; other site
1171376003035	putative PBP binding loops; other site
1171376003036	ABC-ATPase subunit interface; other site
1171376003037	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1171376003038	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1171376003039	peptide binding site [polypeptide binding]; other site
1171376003040	hypothetical protein; Provisional; Region: PRK11111
1171376003041	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1171376003042	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1171376003043	putative catalytic cysteine [active]
1171376003044	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1171376003045	putative active site [active]
1171376003046	metal binding site [ion binding]; metal-binding site
1171376003047	thymidine kinase; Provisional; Region: PRK04296
1171376003048	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1171376003049	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1171376003050	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1171376003051	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1171376003052	active site
1171376003053	tetramer interface; other site
1171376003054	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376003055	active site
1171376003056	response regulator of RpoS; Provisional; Region: PRK10693
1171376003057	phosphorylation site [posttranslational modification]
1171376003058	intermolecular recognition site; other site
1171376003059	dimerization interface [polypeptide binding]; other site
1171376003060	hypothetical protein; Provisional; Region: PRK10279
1171376003061	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1171376003062	active site
1171376003063	nucleophile elbow; other site
1171376003064	SEC-C motif; Region: SEC-C; pfam02810
1171376003065	hypothetical protein; Provisional; Region: PRK04233
1171376003066	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1171376003067	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1171376003068	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1171376003069	putative active site [active]
1171376003070	putative substrate binding site [chemical binding]; other site
1171376003071	putative cosubstrate binding site; other site
1171376003072	catalytic site [active]
1171376003073	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1171376003074	Sel1-like repeats; Region: SEL1; smart00671
1171376003075	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1171376003076	Sel1-like repeats; Region: SEL1; smart00671
1171376003077	Sel1-like repeats; Region: SEL1; smart00671
1171376003078	Sel1-like repeats; Region: SEL1; smart00671
1171376003079	Sel1-like repeats; Region: SEL1; smart00671
1171376003080	Sel1-like repeats; Region: SEL1; smart00671
1171376003081	Sel1-like repeats; Region: SEL1; smart00671
1171376003082	Sel1-like repeats; Region: SEL1; smart00671
1171376003083	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1171376003084	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1171376003085	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1171376003086	4Fe-4S binding domain; Region: Fer4; cl02805
1171376003087	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1171376003088	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1171376003089	[4Fe-4S] binding site [ion binding]; other site
1171376003090	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1171376003091	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1171376003092	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1171376003093	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1171376003094	molybdopterin cofactor binding site; other site
1171376003095	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1171376003096	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1171376003097	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1171376003098	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376003099	dimerization interface [polypeptide binding]; other site
1171376003100	Histidine kinase; Region: HisKA_3; pfam07730
1171376003101	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376003102	ATP binding site [chemical binding]; other site
1171376003103	Mg2+ binding site [ion binding]; other site
1171376003104	G-X-G motif; other site
1171376003105	transcriptional regulator NarL; Provisional; Region: PRK10651
1171376003106	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376003107	active site
1171376003108	phosphorylation site [posttranslational modification]
1171376003109	intermolecular recognition site; other site
1171376003110	dimerization interface [polypeptide binding]; other site
1171376003111	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376003112	DNA binding residues [nucleotide binding]
1171376003113	dimerization interface [polypeptide binding]; other site
1171376003114	putative invasin; Provisional; Region: PRK10177
1171376003115	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1171376003116	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1171376003117	cation transport regulator; Reviewed; Region: chaB; PRK09582
1171376003118	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1171376003119	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1171376003120	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
1171376003121	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1171376003122	hypothetical protein; Provisional; Region: PRK10941
1171376003123	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1171376003124	hypothetical protein; Provisional; Region: PRK10278
1171376003125	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1171376003126	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376003127	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1171376003128	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1171376003129	RF-1 domain; Region: RF-1; pfam00472
1171376003130	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1171376003131	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1171376003132	tRNA; other site
1171376003133	putative tRNA binding site [nucleotide binding]; other site
1171376003134	putative NADP binding site [chemical binding]; other site
1171376003135	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1171376003136	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
1171376003137	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1171376003138	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1171376003139	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1171376003140	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1171376003141	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1171376003142	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1171376003143	active site
1171376003144	putative transporter; Provisional; Region: PRK11660
1171376003145	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1171376003146	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1171376003147	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1171376003148	hypothetical protein; Provisional; Region: PRK10692
1171376003149	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1171376003150	putative active site [active]
1171376003151	catalytic residue [active]
1171376003152	GTP-binding protein YchF; Reviewed; Region: PRK09601
1171376003153	YchF GTPase; Region: YchF; cd01900
1171376003154	G1 box; other site
1171376003155	GTP/Mg2+ binding site [chemical binding]; other site
1171376003156	Switch I region; other site
1171376003157	G2 box; other site
1171376003158	Switch II region; other site
1171376003159	G3 box; other site
1171376003160	G4 box; other site
1171376003161	G5 box; other site
1171376003162	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1171376003163	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
1171376003164	Protein of unknown function (DUF4427); Region: DUF4427; pfam14468
1171376003165	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1171376003166	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1171376003167	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1171376003168	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1171376003169	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1171376003170	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
1171376003171	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1171376003172	putative substrate-binding site; other site
1171376003173	nickel binding site [ion binding]; other site
1171376003174	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1171376003175	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1171376003176	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1171376003177	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
1171376003178	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1171376003179	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
1171376003180	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1171376003181	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
1171376003182	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1171376003183	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1171376003184	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1171376003185	NAD(P) binding site [chemical binding]; other site
1171376003186	trehalase; Provisional; Region: treA; PRK13271
1171376003187	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1171376003188	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
1171376003189	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1171376003190	Flagellar regulator YcgR; Region: YcgR; pfam07317
1171376003191	PilZ domain; Region: PilZ; pfam07238
1171376003192	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1171376003193	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1171376003194	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1171376003195	catalytic residue [active]
1171376003196	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1171376003197	dimer interface [polypeptide binding]; other site
1171376003198	catalytic triad [active]
1171376003199	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1171376003200	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1171376003201	TrkA-C domain; Region: TrkA_C; pfam02080
1171376003202	Transporter associated domain; Region: CorC_HlyC; smart01091
1171376003203	alanine racemase; Reviewed; Region: dadX; PRK03646
1171376003204	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1171376003205	active site
1171376003206	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1171376003207	substrate binding site [chemical binding]; other site
1171376003208	catalytic residues [active]
1171376003209	dimer interface [polypeptide binding]; other site
1171376003210	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1171376003211	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1171376003212	SpoVR family protein; Provisional; Region: PRK11767
1171376003213	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1171376003214	fatty acid metabolism regulator; Provisional; Region: PRK04984
1171376003215	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376003216	DNA-binding site [nucleotide binding]; DNA binding site
1171376003217	FadR C-terminal domain; Region: FadR_C; pfam07840
1171376003218	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1171376003219	transmembrane helices; other site
1171376003220	disulfide bond formation protein B; Provisional; Region: PRK01749
1171376003221	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1171376003222	GnsA/GnsB family; Region: GnsAB; pfam08178
1171376003223	hypothetical protein; Provisional; Region: PRK05170
1171376003224	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1171376003225	hypothetical protein; Provisional; Region: PRK10691
1171376003226	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
1171376003227	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1171376003228	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1171376003229	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1171376003230	cell division inhibitor MinD; Provisional; Region: PRK10818
1171376003231	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1171376003232	Switch I; other site
1171376003233	Switch II; other site
1171376003234	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1171376003235	ribonuclease D; Provisional; Region: PRK10829
1171376003236	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1171376003237	catalytic site [active]
1171376003238	putative active site [active]
1171376003239	putative substrate binding site [chemical binding]; other site
1171376003240	HRDC domain; Region: HRDC; cl02578
1171376003241	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1171376003242	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1171376003243	acyl-activating enzyme (AAE) consensus motif; other site
1171376003244	putative AMP binding site [chemical binding]; other site
1171376003245	putative active site [active]
1171376003246	putative CoA binding site [chemical binding]; other site
1171376003247	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
1171376003248	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1171376003249	Glycoprotease family; Region: Peptidase_M22; pfam00814
1171376003250	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1171376003251	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1171376003252	DEAD_2; Region: DEAD_2; pfam06733
1171376003253	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1171376003254	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1171376003255	homotrimer interaction site [polypeptide binding]; other site
1171376003256	putative active site [active]
1171376003257	hypothetical protein; Provisional; Region: PRK05114
1171376003258	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1171376003259	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1171376003260	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
1171376003261	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1171376003262	putative active site [active]
1171376003263	putative CoA binding site [chemical binding]; other site
1171376003264	nudix motif; other site
1171376003265	metal binding site [ion binding]; metal-binding site
1171376003266	L-serine deaminase; Provisional; Region: PRK15023
1171376003267	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1171376003268	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1171376003269	phage resistance protein; Provisional; Region: PRK10551
1171376003270	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1171376003271	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376003272	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1171376003273	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1171376003274	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1171376003275	Transporter associated domain; Region: CorC_HlyC; smart01091
1171376003276	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1171376003277	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1171376003278	active pocket/dimerization site; other site
1171376003279	active site
1171376003280	phosphorylation site [posttranslational modification]
1171376003281	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1171376003282	active site
1171376003283	phosphorylation site [posttranslational modification]
1171376003284	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1171376003285	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1171376003286	hypothetical protein; Provisional; Region: PRK02913
1171376003287	hypothetical protein; Provisional; Region: PRK11469
1171376003288	Domain of unknown function DUF; Region: DUF204; pfam02659
1171376003289	Domain of unknown function DUF; Region: DUF204; pfam02659
1171376003290	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1171376003291	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376003292	S-adenosylmethionine binding site [chemical binding]; other site
1171376003293	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1171376003294	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1171376003295	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1171376003296	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1171376003297	DNA-binding site [nucleotide binding]; DNA binding site
1171376003298	RNA-binding motif; other site
1171376003299	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
1171376003300	YebO-like protein; Region: YebO; pfam13974
1171376003301	PhoPQ regulatory protein; Provisional; Region: PRK10299
1171376003302	YobH-like protein; Region: YobH; pfam13996
1171376003303	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1171376003304	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1171376003305	dimerization interface [polypeptide binding]; other site
1171376003306	putative Zn2+ binding site [ion binding]; other site
1171376003307	putative DNA binding site [nucleotide binding]; other site
1171376003308	Bacterial transcriptional regulator; Region: IclR; pfam01614
1171376003309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376003310	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1171376003311	putative substrate translocation pore; other site
1171376003312	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376003313	heat shock protein HtpX; Provisional; Region: PRK05457
1171376003314	carboxy-terminal protease; Provisional; Region: PRK11186
1171376003315	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1171376003316	protein binding site [polypeptide binding]; other site
1171376003317	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1171376003318	Catalytic dyad [active]
1171376003319	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1171376003320	ProP expression regulator; Provisional; Region: PRK04950
1171376003321	ProQ/FINO family; Region: ProQ; pfam04352
1171376003322	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1171376003323	GAF domain; Region: GAF_2; pfam13185
1171376003324	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1171376003325	Paraquat-inducible protein A; Region: PqiA; pfam04403
1171376003326	Paraquat-inducible protein A; Region: PqiA; pfam04403
1171376003327	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1171376003328	mce related protein; Region: MCE; pfam02470
1171376003329	mce related protein; Region: MCE; pfam02470
1171376003330	mce related protein; Region: MCE; pfam02470
1171376003331	mce related protein; Region: MCE; pfam02470
1171376003332	mce related protein; Region: MCE; pfam02470
1171376003333	mce related protein; Region: MCE; pfam02470
1171376003334	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1171376003335	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
1171376003336	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1171376003337	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1171376003338	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1171376003339	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
1171376003340	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1171376003341	type III secretion protein SopE2; Provisional; Region: PRK15280
1171376003342	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
1171376003343	SopE GEF domain; Region: SopE_GEF; pfam07487
1171376003344	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
1171376003345	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376003346	Coenzyme A binding pocket [chemical binding]; other site
1171376003347	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1171376003348	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1171376003349	MULE transposase domain; Region: MULE; pfam10551
1171376003350	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1171376003351	DNA binding site [nucleotide binding]
1171376003352	active site
1171376003353	Int/Topo IB signature motif; other site
1171376003354	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1171376003355	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1171376003356	EamA-like transporter family; Region: EamA; pfam00892
1171376003357	EamA-like transporter family; Region: EamA; pfam00892
1171376003358	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
1171376003359	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1171376003360	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1171376003361	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
1171376003362	ADP-ribose binding site [chemical binding]; other site
1171376003363	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1171376003364	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1171376003365	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
1171376003366	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1171376003367	exonuclease VIII; Reviewed; Region: PRK09709
1171376003368	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1171376003369	DNA binding site [nucleotide binding]
1171376003370	active site
1171376003371	Int/Topo IB signature motif; other site
1171376003372	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1171376003373	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1171376003374	hypothetical protein; Provisional; Region: PRK10301
1171376003375	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1171376003376	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1171376003377	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
1171376003378	exodeoxyribonuclease X; Provisional; Region: PRK07983
1171376003379	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1171376003380	active site
1171376003381	catalytic site [active]
1171376003382	substrate binding site [chemical binding]; other site
1171376003383	protease 2; Provisional; Region: PRK10115
1171376003384	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1171376003385	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1171376003386	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1171376003387	putative metal binding site [ion binding]; other site
1171376003388	hypothetical protein; Provisional; Region: PRK13680
1171376003389	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
1171376003390	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1171376003391	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1171376003392	ATP-grasp domain; Region: ATP-grasp; pfam02222
1171376003393	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1171376003394	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1171376003395	active site
1171376003396	intersubunit interface [polypeptide binding]; other site
1171376003397	catalytic residue [active]
1171376003398	phosphogluconate dehydratase; Validated; Region: PRK09054
1171376003399	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1171376003400	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1171376003401	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1171376003402	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1171376003403	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1171376003404	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1171376003405	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1171376003406	putative active site [active]
1171376003407	pyruvate kinase; Provisional; Region: PRK05826
1171376003408	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1171376003409	domain interfaces; other site
1171376003410	active site
1171376003411	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1171376003412	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1171376003413	putative acyl-acceptor binding pocket; other site
1171376003414	putative peptidase; Provisional; Region: PRK11649
1171376003415	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1171376003416	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1171376003417	Peptidase family M23; Region: Peptidase_M23; pfam01551
1171376003418	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1171376003419	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1171376003420	metal binding site [ion binding]; metal-binding site
1171376003421	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1171376003422	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1171376003423	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1171376003424	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1171376003425	ABC-ATPase subunit  interface; other site
1171376003426	dimer interface [polypeptide binding]; other site
1171376003427	putative PBP binding regions; other site
1171376003428	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1171376003429	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376003430	Walker A motif; other site
1171376003431	ATP binding site [chemical binding]; other site
1171376003432	Walker B motif; other site
1171376003433	arginine finger; other site
1171376003434	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1171376003435	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1171376003436	RuvA N terminal domain; Region: RuvA_N; pfam01330
1171376003437	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1171376003438	hypothetical protein; Provisional; Region: PRK11470
1171376003439	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1171376003440	active site
1171376003441	putative DNA-binding cleft [nucleotide binding]; other site
1171376003442	dimer interface [polypeptide binding]; other site
1171376003443	hypothetical protein; Validated; Region: PRK00110
1171376003444	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1171376003445	nudix motif; other site
1171376003446	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1171376003447	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1171376003448	dimer interface [polypeptide binding]; other site
1171376003449	anticodon binding site; other site
1171376003450	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1171376003451	homodimer interface [polypeptide binding]; other site
1171376003452	motif 1; other site
1171376003453	active site
1171376003454	motif 2; other site
1171376003455	GAD domain; Region: GAD; pfam02938
1171376003456	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1171376003457	active site
1171376003458	motif 3; other site
1171376003459	Isochorismatase family; Region: Isochorismatase; pfam00857
1171376003460	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1171376003461	catalytic triad [active]
1171376003462	conserved cis-peptide bond; other site
1171376003463	hypothetical protein; Provisional; Region: PRK10302
1171376003464	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1171376003465	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376003466	S-adenosylmethionine binding site [chemical binding]; other site
1171376003467	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376003468	S-adenosylmethionine binding site [chemical binding]; other site
1171376003469	copper homeostasis protein CutC; Provisional; Region: PRK11572
1171376003470	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1171376003471	putative metal binding site [ion binding]; other site
1171376003472	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1171376003473	arginyl-tRNA synthetase; Region: argS; TIGR00456
1171376003474	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1171376003475	active site
1171376003476	HIGH motif; other site
1171376003477	KMSK motif region; other site
1171376003478	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1171376003479	tRNA binding surface [nucleotide binding]; other site
1171376003480	anticodon binding site; other site
1171376003481	penicillin-binding protein 2; Provisional; Region: PRK10795
1171376003482	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1171376003483	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1171376003484	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1171376003485	Flagellar protein FlhE; Region: FlhE; pfam06366
1171376003486	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1171376003487	FHIPEP family; Region: FHIPEP; pfam00771
1171376003488	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1171376003489	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1171376003490	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1171376003491	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1171376003492	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376003493	active site
1171376003494	phosphorylation site [posttranslational modification]
1171376003495	intermolecular recognition site; other site
1171376003496	dimerization interface [polypeptide binding]; other site
1171376003497	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1171376003498	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376003499	active site
1171376003500	phosphorylation site [posttranslational modification]
1171376003501	intermolecular recognition site; other site
1171376003502	dimerization interface [polypeptide binding]; other site
1171376003503	CheB methylesterase; Region: CheB_methylest; pfam01339
1171376003504	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1171376003505	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1171376003506	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376003507	S-adenosylmethionine binding site [chemical binding]; other site
1171376003508	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1171376003509	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1171376003510	dimer interface [polypeptide binding]; other site
1171376003511	ligand binding site [chemical binding]; other site
1171376003512	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376003513	dimerization interface [polypeptide binding]; other site
1171376003514	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1171376003515	dimer interface [polypeptide binding]; other site
1171376003516	putative CheW interface [polypeptide binding]; other site
1171376003517	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1171376003518	putative CheA interaction surface; other site
1171376003519	chemotaxis protein CheA; Provisional; Region: PRK10547
1171376003520	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1171376003521	putative binding surface; other site
1171376003522	active site
1171376003523	CheY binding; Region: CheY-binding; pfam09078
1171376003524	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1171376003525	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376003526	ATP binding site [chemical binding]; other site
1171376003527	Mg2+ binding site [ion binding]; other site
1171376003528	G-X-G motif; other site
1171376003529	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1171376003530	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1171376003531	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1171376003532	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1171376003533	ligand binding site [chemical binding]; other site
1171376003534	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1171376003535	flagellar motor protein MotA; Validated; Region: PRK09110
1171376003536	transcriptional activator FlhC; Provisional; Region: PRK12722
1171376003537	transcriptional activator FlhD; Provisional; Region: PRK02909
1171376003538	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1171376003539	Ligand Binding Site [chemical binding]; other site
1171376003540	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1171376003541	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1171376003542	active site
1171376003543	homotetramer interface [polypeptide binding]; other site
1171376003544	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
1171376003545	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1171376003546	DJ-1 family protein; Region: not_thiJ; TIGR01383
1171376003547	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1171376003548	conserved cys residue [active]
1171376003549	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1171376003550	Ferritin-like domain; Region: Ferritin; pfam00210
1171376003551	ferroxidase diiron center [ion binding]; other site
1171376003552	hypothetical protein; Provisional; Region: PRK09273
1171376003553	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
1171376003554	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
1171376003555	YecR-like lipoprotein; Region: YecR; pfam13992
1171376003556	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1171376003557	Ferritin-like domain; Region: Ferritin; pfam00210
1171376003558	ferroxidase diiron center [ion binding]; other site
1171376003559	probable metal-binding protein; Region: matur_matur; TIGR03853
1171376003560	tyrosine transporter TyrP; Provisional; Region: PRK15132
1171376003561	aromatic amino acid transport protein; Region: araaP; TIGR00837
1171376003562	hypothetical protein; Provisional; Region: PRK10396
1171376003563	yecA family protein; Region: ygfB_yecA; TIGR02292
1171376003564	SEC-C motif; Region: SEC-C; pfam02810
1171376003565	glucose-6-phosphate 1-dehydrogenase; Region: PLN02640
1171376003566	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
1171376003567	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
1171376003568	NlpC/P60 family; Region: NLPC_P60; cl17555
1171376003569	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1171376003570	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1171376003571	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1171376003572	GIY-YIG motif/motif A; other site
1171376003573	active site
1171376003574	catalytic site [active]
1171376003575	putative DNA binding site [nucleotide binding]; other site
1171376003576	metal binding site [ion binding]; metal-binding site
1171376003577	UvrB/uvrC motif; Region: UVR; pfam02151
1171376003578	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1171376003579	Helix-hairpin-helix motif; Region: HHH; pfam00633
1171376003580	response regulator; Provisional; Region: PRK09483
1171376003581	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376003582	active site
1171376003583	phosphorylation site [posttranslational modification]
1171376003584	intermolecular recognition site; other site
1171376003585	dimerization interface [polypeptide binding]; other site
1171376003586	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376003587	DNA binding residues [nucleotide binding]
1171376003588	dimerization interface [polypeptide binding]; other site
1171376003589	hypothetical protein; Provisional; Region: PRK10613
1171376003590	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1171376003591	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1171376003592	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376003593	DNA binding residues [nucleotide binding]
1171376003594	dimerization interface [polypeptide binding]; other site
1171376003595	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1171376003596	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1171376003597	Walker A/P-loop; other site
1171376003598	ATP binding site [chemical binding]; other site
1171376003599	Q-loop/lid; other site
1171376003600	ABC transporter signature motif; other site
1171376003601	Walker B; other site
1171376003602	D-loop; other site
1171376003603	H-loop/switch region; other site
1171376003604	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1171376003605	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1171376003606	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376003607	dimer interface [polypeptide binding]; other site
1171376003608	conserved gate region; other site
1171376003609	putative PBP binding loops; other site
1171376003610	ABC-ATPase subunit interface; other site
1171376003611	D-cysteine desulfhydrase; Validated; Region: PRK03910
1171376003612	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1171376003613	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376003614	catalytic residue [active]
1171376003615	cystine transporter subunit; Provisional; Region: PRK11260
1171376003616	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376003617	substrate binding pocket [chemical binding]; other site
1171376003618	membrane-bound complex binding site; other site
1171376003619	hinge residues; other site
1171376003620	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1171376003621	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1171376003622	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1171376003623	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1171376003624	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1171376003625	DNA binding residues [nucleotide binding]
1171376003626	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1171376003627	flagellin; Validated; Region: PRK08026
1171376003628	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1171376003629	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
1171376003630	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1171376003631	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1171376003632	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1171376003633	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1171376003634	flagellar protein FliS; Validated; Region: fliS; PRK05685
1171376003635	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
1171376003636	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1171376003637	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1171376003638	active site
1171376003639	Na/Ca binding site [ion binding]; other site
1171376003640	catalytic site [active]
1171376003641	lipoprotein; Provisional; Region: PRK10397
1171376003642	putative inner membrane protein; Provisional; Region: PRK11099
1171376003643	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1171376003644	CPxP  motif; other site
1171376003645	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1171376003646	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1171376003647	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1171376003648	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1171376003649	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1171376003650	FliG C-terminal domain; Region: FliG_C; pfam01706
1171376003651	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1171376003652	Flagellar assembly protein FliH; Region: FliH; pfam02108
1171376003653	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1171376003654	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1171376003655	Walker A motif/ATP binding site; other site
1171376003656	Walker B motif; other site
1171376003657	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1171376003658	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1171376003659	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
1171376003660	flagellar hook-length control protein; Provisional; Region: PRK10118
1171376003661	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1171376003662	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1171376003663	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1171376003664	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1171376003665	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1171376003666	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1171376003667	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1171376003668	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1171376003669	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1171376003670	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1171376003671	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376003672	DNA binding residues [nucleotide binding]
1171376003673	dimerization interface [polypeptide binding]; other site
1171376003674	hypothetical protein; Provisional; Region: PRK10708
1171376003675	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1171376003676	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1171376003677	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376003678	active site
1171376003679	motif I; other site
1171376003680	motif II; other site
1171376003681	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1171376003682	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376003683	metal binding site [ion binding]; metal-binding site
1171376003684	active site
1171376003685	I-site; other site
1171376003686	Uncharacterized small protein [Function unknown]; Region: COG5475
1171376003687	hypothetical protein; Provisional; Region: PRK10062
1171376003688	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1171376003689	EamA-like transporter family; Region: EamA; pfam00892
1171376003690	EamA-like transporter family; Region: EamA; pfam00892
1171376003691	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1171376003692	additional DNA contacts [nucleotide binding]; other site
1171376003693	mismatch recognition site; other site
1171376003694	active site
1171376003695	zinc binding site [ion binding]; other site
1171376003696	DNA intercalation site [nucleotide binding]; other site
1171376003697	DNA cytosine methylase; Provisional; Region: PRK10458
1171376003698	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1171376003699	cofactor binding site; other site
1171376003700	DNA binding site [nucleotide binding]
1171376003701	substrate interaction site [chemical binding]; other site
1171376003702	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1171376003703	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1171376003704	Zn2+ binding site [ion binding]; other site
1171376003705	Mg2+ binding site [ion binding]; other site
1171376003706	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1171376003707	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1171376003708	trimer interface [polypeptide binding]; other site
1171376003709	eyelet of channel; other site
1171376003710	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1171376003711	DNA-binding site [nucleotide binding]; DNA binding site
1171376003712	RNA-binding motif; other site
1171376003713	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1171376003714	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1171376003715	active site
1171376003716	DNA binding site [nucleotide binding]
1171376003717	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1171376003718	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1171376003719	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1171376003720	Catalytic site [active]
1171376003721	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1171376003722	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1171376003723	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1171376003724	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1171376003725	putative protease; Region: PHA00666
1171376003726	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
1171376003727	Integrase; Region: Integrase_1; pfam12835
1171376003728	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
1171376003729	DDE superfamily endonuclease; Region: DDE_3; pfam13358
1171376003730	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1171376003731	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1171376003732	Sel1 repeat; Region: Sel1; pfam08238
1171376003733	Sel1-like repeats; Region: SEL1; smart00671
1171376003734	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
1171376003735	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cl00723
1171376003736	AMP nucleosidase; Provisional; Region: PRK08292
1171376003737	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1171376003738	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1171376003739	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1171376003740	MATE family multidrug exporter; Provisional; Region: PRK10189
1171376003741	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1171376003742	L,D-transpeptidase; Provisional; Region: PRK10190
1171376003743	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1171376003744	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1171376003745	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1171376003746	putative dimer interface [polypeptide binding]; other site
1171376003747	active site pocket [active]
1171376003748	putative cataytic base [active]
1171376003749	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1171376003750	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1171376003751	homotrimer interface [polypeptide binding]; other site
1171376003752	Walker A motif; other site
1171376003753	GTP binding site [chemical binding]; other site
1171376003754	Walker B motif; other site
1171376003755	cobyric acid synthase; Provisional; Region: PRK00784
1171376003756	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1171376003757	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1171376003758	catalytic triad [active]
1171376003759	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
1171376003760	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1171376003761	Walker A/P-loop; other site
1171376003762	ATP binding site [chemical binding]; other site
1171376003763	Q-loop/lid; other site
1171376003764	ABC transporter signature motif; other site
1171376003765	Walker B; other site
1171376003766	D-loop; other site
1171376003767	H-loop/switch region; other site
1171376003768	cobalt transport protein CbiQ; Provisional; Region: PRK15485
1171376003769	cobalt transport protein CbiN; Provisional; Region: PRK02898
1171376003770	cobalt transport protein CbiM; Validated; Region: PRK08319
1171376003771	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
1171376003772	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1171376003773	active site
1171376003774	SAM binding site [chemical binding]; other site
1171376003775	homodimer interface [polypeptide binding]; other site
1171376003776	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
1171376003777	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
1171376003778	active site
1171376003779	C-terminal domain interface [polypeptide binding]; other site
1171376003780	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
1171376003781	active site
1171376003782	N-terminal domain interface [polypeptide binding]; other site
1171376003783	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1171376003784	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
1171376003785	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1171376003786	active site
1171376003787	SAM binding site [chemical binding]; other site
1171376003788	homodimer interface [polypeptide binding]; other site
1171376003789	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1171376003790	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1171376003791	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1171376003792	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1171376003793	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1171376003794	active site
1171376003795	SAM binding site [chemical binding]; other site
1171376003796	homodimer interface [polypeptide binding]; other site
1171376003797	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
1171376003798	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376003799	S-adenosylmethionine binding site [chemical binding]; other site
1171376003800	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1171376003801	active site
1171376003802	putative homodimer interface [polypeptide binding]; other site
1171376003803	SAM binding site [chemical binding]; other site
1171376003804	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1171376003805	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
1171376003806	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1171376003807	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
1171376003808	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1171376003809	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1171376003810	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1171376003811	catalytic triad [active]
1171376003812	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
1171376003813	Sensory domain found in PocR; Region: PocR; pfam10114
1171376003814	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376003815	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1171376003816	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376003817	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1171376003818	amphipathic channel; other site
1171376003819	Asn-Pro-Ala signature motifs; other site
1171376003820	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1171376003821	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1171376003822	Hexamer interface [polypeptide binding]; other site
1171376003823	Putative hexagonal pore residue; other site
1171376003824	propanediol utilization protein PduB; Provisional; Region: PRK15415
1171376003825	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
1171376003826	putative hexamer interface [polypeptide binding]; other site
1171376003827	putative hexagonal pore; other site
1171376003828	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
1171376003829	putative hexamer interface [polypeptide binding]; other site
1171376003830	putative hexagonal pore; other site
1171376003831	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
1171376003832	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
1171376003833	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
1171376003834	alpha-beta subunit interface [polypeptide binding]; other site
1171376003835	alpha-gamma subunit interface [polypeptide binding]; other site
1171376003836	active site
1171376003837	substrate and K+ binding site; other site
1171376003838	K+ binding site [ion binding]; other site
1171376003839	cobalamin binding site [chemical binding]; other site
1171376003840	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
1171376003841	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
1171376003842	Cell division protein FtsA; Region: FtsA; cl17206
1171376003843	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
1171376003844	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
1171376003845	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1171376003846	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1171376003847	Hexamer interface [polypeptide binding]; other site
1171376003848	Putative hexagonal pore residue; other site
1171376003849	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1171376003850	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
1171376003851	putative hexamer interface [polypeptide binding]; other site
1171376003852	putative hexagonal pore; other site
1171376003853	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
1171376003854	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1171376003855	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1171376003856	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
1171376003857	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1171376003858	Hexamer/Pentamer interface [polypeptide binding]; other site
1171376003859	central pore; other site
1171376003860	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
1171376003861	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
1171376003862	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1171376003863	putative catalytic cysteine [active]
1171376003864	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1171376003865	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
1171376003866	putative active site [active]
1171376003867	metal binding site [ion binding]; metal-binding site
1171376003868	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1171376003869	SLBB domain; Region: SLBB; pfam10531
1171376003870	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1171376003871	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
1171376003872	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
1171376003873	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1171376003874	putative hexamer interface [polypeptide binding]; other site
1171376003875	putative hexagonal pore; other site
1171376003876	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1171376003877	putative hexamer interface [polypeptide binding]; other site
1171376003878	putative hexagonal pore; other site
1171376003879	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1171376003880	putative hexamer interface [polypeptide binding]; other site
1171376003881	putative hexagonal pore; other site
1171376003882	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
1171376003883	G3 box; other site
1171376003884	Switch II region; other site
1171376003885	GTP/Mg2+ binding site [chemical binding]; other site
1171376003886	G4 box; other site
1171376003887	G5 box; other site
1171376003888	propionate kinase; Reviewed; Region: PRK12397
1171376003889	propionate/acetate kinase; Provisional; Region: PRK12379
1171376003890	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
1171376003891	hypothetical protein; Provisional; Region: PRK05423
1171376003892	Predicted membrane protein [Function unknown]; Region: COG1289
1171376003893	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1171376003894	DNA gyrase inhibitor; Provisional; Region: PRK10016
1171376003895	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1171376003896	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1171376003897	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1171376003898	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
1171376003899	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
1171376003900	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1171376003901	4Fe-4S binding domain; Region: Fer4; cl02805
1171376003902	thiosulfate reductase PhsA; Provisional; Region: PRK15488
1171376003903	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1171376003904	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
1171376003905	putative [Fe4-S4] binding site [ion binding]; other site
1171376003906	putative molybdopterin cofactor binding site [chemical binding]; other site
1171376003907	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1171376003908	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
1171376003909	putative molybdopterin cofactor binding site; other site
1171376003910	E3 ubiquitin-protein ligase SopA; Provisional; Region: PRK15377
1171376003911	SopA-like central domain; Region: SopA; pfam13981
1171376003912	SopA-like catalytic domain; Region: SopA_C; pfam13979
1171376003913	exonuclease I; Provisional; Region: sbcB; PRK11779
1171376003914	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1171376003915	active site
1171376003916	catalytic site [active]
1171376003917	substrate binding site [chemical binding]; other site
1171376003918	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1171376003919	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1171376003920	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376003921	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1171376003922	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376003923	dimerization interface [polypeptide binding]; other site
1171376003924	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1171376003925	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1171376003926	putative NAD(P) binding site [chemical binding]; other site
1171376003927	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1171376003928	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1171376003929	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1171376003930	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
1171376003931	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376003932	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376003933	homodimer interface [polypeptide binding]; other site
1171376003934	catalytic residue [active]
1171376003935	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1171376003936	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376003937	active site
1171376003938	motif I; other site
1171376003939	motif II; other site
1171376003940	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1171376003941	putative active site pocket [active]
1171376003942	4-fold oligomerization interface [polypeptide binding]; other site
1171376003943	metal binding residues [ion binding]; metal-binding site
1171376003944	3-fold/trimer interface [polypeptide binding]; other site
1171376003945	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1171376003946	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1171376003947	putative active site [active]
1171376003948	oxyanion strand; other site
1171376003949	catalytic triad [active]
1171376003950	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1171376003951	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1171376003952	catalytic residues [active]
1171376003953	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1171376003954	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1171376003955	substrate binding site [chemical binding]; other site
1171376003956	glutamase interaction surface [polypeptide binding]; other site
1171376003957	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1171376003958	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1171376003959	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1171376003960	metal binding site [ion binding]; metal-binding site
1171376003961	chain length determinant protein WzzB; Provisional; Region: PRK15471
1171376003962	Chain length determinant protein; Region: Wzz; pfam02706
1171376003963	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1171376003964	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1171376003965	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1171376003966	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1171376003967	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1171376003968	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1171376003969	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1171376003970	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1171376003971	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
1171376003972	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1171376003973	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1171376003974	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1171376003975	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
1171376003976	active site
1171376003977	substrate binding site [chemical binding]; other site
1171376003978	metal binding site [ion binding]; metal-binding site
1171376003979	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1171376003980	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1171376003981	Substrate binding site; other site
1171376003982	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1171376003983	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1171376003984	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1171376003985	active site
1171376003986	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1171376003987	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1171376003988	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1171376003989	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1171376003990	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1171376003991	active site
1171376003992	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1171376003993	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
1171376003994	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1171376003995	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1171376003996	NAD(P) binding site [chemical binding]; other site
1171376003997	active site
1171376003998	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1171376003999	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1171376004000	inhibitor-cofactor binding pocket; inhibition site
1171376004001	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376004002	catalytic residue [active]
1171376004003	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
1171376004004	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
1171376004005	NAD binding site [chemical binding]; other site
1171376004006	homotetramer interface [polypeptide binding]; other site
1171376004007	homodimer interface [polypeptide binding]; other site
1171376004008	substrate binding site [chemical binding]; other site
1171376004009	active site
1171376004010	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1171376004011	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1171376004012	substrate binding site; other site
1171376004013	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
1171376004014	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1171376004015	catalytic loop [active]
1171376004016	iron binding site [ion binding]; other site
1171376004017	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1171376004018	FAD binding pocket [chemical binding]; other site
1171376004019	FAD binding motif [chemical binding]; other site
1171376004020	phosphate binding motif [ion binding]; other site
1171376004021	beta-alpha-beta structure motif; other site
1171376004022	NAD binding pocket [chemical binding]; other site
1171376004023	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1171376004024	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
1171376004025	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1171376004026	substrate binding site; other site
1171376004027	tetramer interface; other site
1171376004028	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
1171376004029	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1171376004030	NADP binding site [chemical binding]; other site
1171376004031	active site
1171376004032	putative substrate binding site [chemical binding]; other site
1171376004033	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
1171376004034	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1171376004035	NAD binding site [chemical binding]; other site
1171376004036	substrate binding site [chemical binding]; other site
1171376004037	homodimer interface [polypeptide binding]; other site
1171376004038	active site
1171376004039	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1171376004040	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1171376004041	active site
1171376004042	tetramer interface; other site
1171376004043	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
1171376004044	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
1171376004045	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1171376004046	putative ADP-binding pocket [chemical binding]; other site
1171376004047	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
1171376004048	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
1171376004049	colanic acid exporter; Provisional; Region: PRK10459
1171376004050	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1171376004051	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
1171376004052	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
1171376004053	phosphomannomutase CpsG; Provisional; Region: PRK15414
1171376004054	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1171376004055	active site
1171376004056	substrate binding site [chemical binding]; other site
1171376004057	metal binding site [ion binding]; metal-binding site
1171376004058	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
1171376004059	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1171376004060	Substrate binding site; other site
1171376004061	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1171376004062	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
1171376004063	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1171376004064	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1171376004065	active site
1171376004066	GDP-Mannose binding site [chemical binding]; other site
1171376004067	dimer interface [polypeptide binding]; other site
1171376004068	modified nudix motif
1171376004069	metal binding site [ion binding]; metal-binding site
1171376004070	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1171376004071	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1171376004072	NADP binding site [chemical binding]; other site
1171376004073	active site
1171376004074	putative substrate binding site [chemical binding]; other site
1171376004075	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1171376004076	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1171376004077	NADP-binding site; other site
1171376004078	homotetramer interface [polypeptide binding]; other site
1171376004079	substrate binding site [chemical binding]; other site
1171376004080	homodimer interface [polypeptide binding]; other site
1171376004081	active site
1171376004082	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
1171376004083	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1171376004084	putative trimer interface [polypeptide binding]; other site
1171376004085	putative active site [active]
1171376004086	putative substrate binding site [chemical binding]; other site
1171376004087	putative CoA binding site [chemical binding]; other site
1171376004088	putative glycosyl transferase; Provisional; Region: PRK10063
1171376004089	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1171376004090	metal-binding site
1171376004091	putative colanic acid biosynthesis protein; Provisional; Region: wcaD; cl08075
1171376004092	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
1171376004093	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1171376004094	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1171376004095	putative acyl transferase; Provisional; Region: PRK10191
1171376004096	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1171376004097	trimer interface [polypeptide binding]; other site
1171376004098	active site
1171376004099	substrate binding site [chemical binding]; other site
1171376004100	CoA binding site [chemical binding]; other site
1171376004101	putative glycosyl transferase; Provisional; Region: PRK10018
1171376004102	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1171376004103	active site
1171376004104	tyrosine kinase; Provisional; Region: PRK11519
1171376004105	Chain length determinant protein; Region: Wzz; pfam02706
1171376004106	Chain length determinant protein; Region: Wzz; cl15801
1171376004107	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1171376004108	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1171376004109	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1171376004110	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1171376004111	active site
1171376004112	polysaccharide export protein Wza; Provisional; Region: PRK15078
1171376004113	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1171376004114	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1171376004115	FOG: CBS domain [General function prediction only]; Region: COG0517
1171376004116	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1171376004117	Transporter associated domain; Region: CorC_HlyC; smart01091
1171376004118	putative assembly protein; Provisional; Region: PRK10833
1171376004119	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1171376004120	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1171376004121	trimer interface [polypeptide binding]; other site
1171376004122	active site
1171376004123	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1171376004124	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1171376004125	ATP-binding site [chemical binding]; other site
1171376004126	Sugar specificity; other site
1171376004127	Pyrimidine base specificity; other site
1171376004128	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
1171376004129	PAS domain S-box; Region: sensory_box; TIGR00229
1171376004130	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1171376004131	putative active site [active]
1171376004132	heme pocket [chemical binding]; other site
1171376004133	PAS domain S-box; Region: sensory_box; TIGR00229
1171376004134	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1171376004135	putative active site [active]
1171376004136	heme pocket [chemical binding]; other site
1171376004137	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1171376004138	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376004139	metal binding site [ion binding]; metal-binding site
1171376004140	active site
1171376004141	I-site; other site
1171376004142	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376004143	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1171376004144	AlkA N-terminal domain; Region: AlkA_N; pfam06029
1171376004145	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1171376004146	minor groove reading motif; other site
1171376004147	helix-hairpin-helix signature motif; other site
1171376004148	substrate binding pocket [chemical binding]; other site
1171376004149	active site
1171376004150	putative chaperone; Provisional; Region: PRK11678
1171376004151	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1171376004152	nucleotide binding site [chemical binding]; other site
1171376004153	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1171376004154	SBD interface [polypeptide binding]; other site
1171376004155	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1171376004156	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1171376004157	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376004158	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1171376004159	Protein export membrane protein; Region: SecD_SecF; cl14618
1171376004160	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1171376004161	putative transporter; Provisional; Region: PRK10504
1171376004162	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376004163	putative substrate translocation pore; other site
1171376004164	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1171376004165	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376004166	dimerization interface [polypeptide binding]; other site
1171376004167	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376004168	dimer interface [polypeptide binding]; other site
1171376004169	phosphorylation site [posttranslational modification]
1171376004170	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376004171	ATP binding site [chemical binding]; other site
1171376004172	Mg2+ binding site [ion binding]; other site
1171376004173	G-X-G motif; other site
1171376004174	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1171376004175	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376004176	active site
1171376004177	phosphorylation site [posttranslational modification]
1171376004178	intermolecular recognition site; other site
1171376004179	dimerization interface [polypeptide binding]; other site
1171376004180	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376004181	DNA binding site [nucleotide binding]
1171376004182	PcfJ-like protein; Region: PcfJ; pfam14284
1171376004183	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1171376004184	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
1171376004185	putative protease; Provisional; Region: PRK15452
1171376004186	Peptidase family U32; Region: Peptidase_U32; pfam01136
1171376004187	type III secretion system protein; Provisional; Region: PRK15384; cl14665
1171376004188	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
1171376004189	lipid kinase; Reviewed; Region: PRK13054
1171376004190	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1171376004191	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1171376004192	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1171376004193	putative active site; other site
1171376004194	catalytic residue [active]
1171376004195	nucleoside transporter; Region: 2A0110; TIGR00889
1171376004196	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376004197	putative substrate translocation pore; other site
1171376004198	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1171376004199	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376004200	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1171376004201	substrate binding site [chemical binding]; other site
1171376004202	ATP binding site [chemical binding]; other site
1171376004203	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1171376004204	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376004205	DNA-binding site [nucleotide binding]; DNA binding site
1171376004206	UTRA domain; Region: UTRA; pfam07702
1171376004207	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1171376004208	dimer interface [polypeptide binding]; other site
1171376004209	substrate binding site [chemical binding]; other site
1171376004210	ATP binding site [chemical binding]; other site
1171376004211	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1171376004212	substrate binding site [chemical binding]; other site
1171376004213	multimerization interface [polypeptide binding]; other site
1171376004214	ATP binding site [chemical binding]; other site
1171376004215	Predicted integral membrane protein [Function unknown]; Region: COG5455
1171376004216	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
1171376004217	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
1171376004218	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
1171376004219	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376004220	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376004221	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376004222	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
1171376004223	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376004224	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376004225	fimbrial chaperone protein; Provisional; Region: PRK15220
1171376004226	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
1171376004227	antiporter inner membrane protein; Provisional; Region: PRK11670
1171376004228	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1171376004229	Walker A motif; other site
1171376004230	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1171376004231	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1171376004232	active site
1171376004233	HIGH motif; other site
1171376004234	KMSKS motif; other site
1171376004235	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1171376004236	tRNA binding surface [nucleotide binding]; other site
1171376004237	anticodon binding site; other site
1171376004238	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1171376004239	dimer interface [polypeptide binding]; other site
1171376004240	putative tRNA-binding site [nucleotide binding]; other site
1171376004241	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1171376004242	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1171376004243	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1171376004244	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1171376004245	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1171376004246	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1171376004247	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376004248	active site
1171376004249	phosphorylation site [posttranslational modification]
1171376004250	intermolecular recognition site; other site
1171376004251	dimerization interface [polypeptide binding]; other site
1171376004252	LytTr DNA-binding domain; Region: LytTR; pfam04397
1171376004253	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1171376004254	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1171376004255	GAF domain; Region: GAF; pfam01590
1171376004256	Histidine kinase; Region: His_kinase; pfam06580
1171376004257	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376004258	ATP binding site [chemical binding]; other site
1171376004259	Mg2+ binding site [ion binding]; other site
1171376004260	G-X-G motif; other site
1171376004261	transcriptional regulator MirA; Provisional; Region: PRK15043
1171376004262	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
1171376004263	DNA binding residues [nucleotide binding]
1171376004264	hypothetical protein; Provisional; Region: PRK13681
1171376004265	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
1171376004266	putative PBP binding loops; other site
1171376004267	ABC-ATPase subunit interface; other site
1171376004268	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1171376004269	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1171376004270	Walker A/P-loop; other site
1171376004271	ATP binding site [chemical binding]; other site
1171376004272	Q-loop/lid; other site
1171376004273	ABC transporter signature motif; other site
1171376004274	Walker B; other site
1171376004275	D-loop; other site
1171376004276	H-loop/switch region; other site
1171376004277	CBS domain; Region: CBS; pfam00571
1171376004278	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376004279	dimer interface [polypeptide binding]; other site
1171376004280	conserved gate region; other site
1171376004281	ABC-ATPase subunit interface; other site
1171376004282	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1171376004283	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1171376004284	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1171376004285	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1171376004286	D-lactate dehydrogenase; Provisional; Region: PRK11183
1171376004287	FAD binding domain; Region: FAD_binding_4; pfam01565
1171376004288	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1171376004289	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1171376004290	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1171376004291	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1171376004292	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1171376004293	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1171376004294	oxidoreductase; Provisional; Region: PRK12743
1171376004295	classical (c) SDRs; Region: SDR_c; cd05233
1171376004296	NAD(P) binding site [chemical binding]; other site
1171376004297	active site
1171376004298	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
1171376004299	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1171376004300	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1171376004301	FMN binding site [chemical binding]; other site
1171376004302	active site
1171376004303	catalytic residues [active]
1171376004304	substrate binding site [chemical binding]; other site
1171376004305	salicylate hydroxylase; Provisional; Region: PRK08163
1171376004306	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1171376004307	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
1171376004308	maleylacetoacetate isomerase; Region: maiA; TIGR01262
1171376004309	C-terminal domain interface [polypeptide binding]; other site
1171376004310	GSH binding site (G-site) [chemical binding]; other site
1171376004311	putative dimer interface [polypeptide binding]; other site
1171376004312	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
1171376004313	dimer interface [polypeptide binding]; other site
1171376004314	N-terminal domain interface [polypeptide binding]; other site
1171376004315	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
1171376004316	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1171376004317	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1171376004318	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
1171376004319	Cupin domain; Region: Cupin_2; pfam07883
1171376004320	Cupin domain; Region: Cupin_2; pfam07883
1171376004321	benzoate transport; Region: 2A0115; TIGR00895
1171376004322	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376004323	putative substrate translocation pore; other site
1171376004324	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1171376004325	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376004326	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376004327	dimerization interface [polypeptide binding]; other site
1171376004328	hypothetical protein; Provisional; Region: PRK01821
1171376004329	hypothetical protein; Provisional; Region: PRK10711
1171376004330	cytidine deaminase; Provisional; Region: PRK09027
1171376004331	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1171376004332	active site
1171376004333	catalytic motif [active]
1171376004334	Zn binding site [ion binding]; other site
1171376004335	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1171376004336	active site
1171376004337	catalytic motif [active]
1171376004338	Zn binding site [ion binding]; other site
1171376004339	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1171376004340	putative active site [active]
1171376004341	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
1171376004342	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1171376004343	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1171376004344	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376004345	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
1171376004346	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
1171376004347	homodimer interface [polypeptide binding]; other site
1171376004348	active site
1171376004349	FMN binding site [chemical binding]; other site
1171376004350	substrate binding site [chemical binding]; other site
1171376004351	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1171376004352	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1171376004353	TM-ABC transporter signature motif; other site
1171376004354	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1171376004355	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1171376004356	Walker A/P-loop; other site
1171376004357	ATP binding site [chemical binding]; other site
1171376004358	Q-loop/lid; other site
1171376004359	ABC transporter signature motif; other site
1171376004360	Walker B; other site
1171376004361	D-loop; other site
1171376004362	H-loop/switch region; other site
1171376004363	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1171376004364	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1171376004365	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1171376004366	ligand binding site [chemical binding]; other site
1171376004367	calcium binding site [ion binding]; other site
1171376004368	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1171376004369	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376004370	DNA binding site [nucleotide binding]
1171376004371	domain linker motif; other site
1171376004372	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1171376004373	dimerization interface (closed form) [polypeptide binding]; other site
1171376004374	ligand binding site [chemical binding]; other site
1171376004375	Predicted membrane protein [Function unknown]; Region: COG2311
1171376004376	hypothetical protein; Provisional; Region: PRK10835
1171376004377	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1171376004378	GTP cyclohydrolase I; Provisional; Region: PLN03044
1171376004379	active site
1171376004380	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1171376004381	S-formylglutathione hydrolase; Region: PLN02442
1171376004382	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376004383	non-specific DNA binding site [nucleotide binding]; other site
1171376004384	salt bridge; other site
1171376004385	sequence-specific DNA binding site [nucleotide binding]; other site
1171376004386	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1171376004387	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1171376004388	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1171376004389	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1171376004390	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1171376004391	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376004392	motif II; other site
1171376004393	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1171376004394	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376004395	putative substrate translocation pore; other site
1171376004396	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
1171376004397	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1171376004398	N-terminal plug; other site
1171376004399	ligand-binding site [chemical binding]; other site
1171376004400	lysine transporter; Provisional; Region: PRK10836
1171376004401	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1171376004402	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376004403	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1171376004404	putative dimerization interface [polypeptide binding]; other site
1171376004405	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1171376004406	endonuclease IV; Provisional; Region: PRK01060
1171376004407	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1171376004408	AP (apurinic/apyrimidinic) site pocket; other site
1171376004409	DNA interaction; other site
1171376004410	Metal-binding active site; metal-binding site
1171376004411	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1171376004412	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1171376004413	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1171376004414	active site
1171376004415	P-loop; other site
1171376004416	phosphorylation site [posttranslational modification]
1171376004417	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1171376004418	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1171376004419	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1171376004420	putative substrate binding site [chemical binding]; other site
1171376004421	putative ATP binding site [chemical binding]; other site
1171376004422	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1171376004423	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376004424	active site
1171376004425	phosphorylation site [posttranslational modification]
1171376004426	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1171376004427	dimerization domain swap beta strand [polypeptide binding]; other site
1171376004428	regulatory protein interface [polypeptide binding]; other site
1171376004429	active site
1171376004430	regulatory phosphorylation site [posttranslational modification]; other site
1171376004431	sugar efflux transporter B; Provisional; Region: PRK15011
1171376004432	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376004433	putative substrate translocation pore; other site
1171376004434	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1171376004435	Flagellin N-methylase; Region: FliB; cl00497
1171376004436	elongation factor P; Provisional; Region: PRK04542
1171376004437	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1171376004438	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1171376004439	RNA binding site [nucleotide binding]; other site
1171376004440	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1171376004441	RNA binding site [nucleotide binding]; other site
1171376004442	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1171376004443	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1171376004444	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1171376004445	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1171376004446	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1171376004447	active site
1171376004448	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1171376004449	NlpC/P60 family; Region: NLPC_P60; pfam00877
1171376004450	phage resistance protein; Provisional; Region: PRK10551
1171376004451	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1171376004452	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376004453	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1171376004454	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1171376004455	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1171376004456	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376004457	dimer interface [polypeptide binding]; other site
1171376004458	conserved gate region; other site
1171376004459	putative PBP binding loops; other site
1171376004460	ABC-ATPase subunit interface; other site
1171376004461	microcin C ABC transporter permease; Provisional; Region: PRK15021
1171376004462	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376004463	dimer interface [polypeptide binding]; other site
1171376004464	conserved gate region; other site
1171376004465	ABC-ATPase subunit interface; other site
1171376004466	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1171376004467	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1171376004468	Walker A/P-loop; other site
1171376004469	ATP binding site [chemical binding]; other site
1171376004470	Q-loop/lid; other site
1171376004471	ABC transporter signature motif; other site
1171376004472	Walker B; other site
1171376004473	D-loop; other site
1171376004474	H-loop/switch region; other site
1171376004475	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1171376004476	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1171376004477	Walker A/P-loop; other site
1171376004478	ATP binding site [chemical binding]; other site
1171376004479	Q-loop/lid; other site
1171376004480	ABC transporter signature motif; other site
1171376004481	Walker B; other site
1171376004482	D-loop; other site
1171376004483	H-loop/switch region; other site
1171376004484	hypothetical protein; Provisional; Region: PRK11835
1171376004485	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376004486	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1171376004487	putative substrate translocation pore; other site
1171376004488	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1171376004489	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1171376004490	RNA binding surface [nucleotide binding]; other site
1171376004491	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1171376004492	active site
1171376004493	uracil binding [chemical binding]; other site
1171376004494	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1171376004495	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1171376004496	ATP binding site [chemical binding]; other site
1171376004497	putative Mg++ binding site [ion binding]; other site
1171376004498	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376004499	nucleotide binding region [chemical binding]; other site
1171376004500	ATP-binding site [chemical binding]; other site
1171376004501	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1171376004502	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1171376004503	5S rRNA interface [nucleotide binding]; other site
1171376004504	CTC domain interface [polypeptide binding]; other site
1171376004505	L16 interface [polypeptide binding]; other site
1171376004506	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1171376004507	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1171376004508	hypothetical protein; Provisional; Region: PRK13689
1171376004509	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1171376004510	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1171376004511	Sulfatase; Region: Sulfatase; cl17466
1171376004512	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1171376004513	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1171376004514	Catalytic site [active]
1171376004515	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1171376004516	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1171376004517	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1171376004518	Phage T4 tail fibre; Region: Phage_T4_gp36; pfam03903
1171376004519	Phage head maturation protease [General function prediction only]; Region: COG3740
1171376004520	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1171376004521	Phage-related protein [Function unknown]; Region: COG4695; cl01923
1171376004522	Predicted P-loop ATPase [General function prediction only]; Region: COG4928
1171376004523	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
1171376004524	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1171376004525	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1171376004526	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
1171376004527	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
1171376004528	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
1171376004529	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1171376004530	Leucine-rich repeats; other site
1171376004531	Substrate binding site [chemical binding]; other site
1171376004532	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1171376004533	DinI-like family; Region: DinI; cl11630
1171376004534	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
1171376004535	transcriptional regulator NarP; Provisional; Region: PRK10403
1171376004536	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376004537	active site
1171376004538	phosphorylation site [posttranslational modification]
1171376004539	intermolecular recognition site; other site
1171376004540	dimerization interface [polypeptide binding]; other site
1171376004541	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376004542	DNA binding residues [nucleotide binding]
1171376004543	dimerization interface [polypeptide binding]; other site
1171376004544	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1171376004545	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1171376004546	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1171376004547	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1171376004548	catalytic residues [active]
1171376004549	central insert; other site
1171376004550	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1171376004551	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1171376004552	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1171376004553	heme exporter protein CcmC; Region: ccmC; TIGR01191
1171376004554	heme exporter protein CcmB; Region: ccmB; TIGR01190
1171376004555	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1171376004556	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376004557	Walker A/P-loop; other site
1171376004558	ATP binding site [chemical binding]; other site
1171376004559	Q-loop/lid; other site
1171376004560	ABC transporter signature motif; other site
1171376004561	Walker B; other site
1171376004562	D-loop; other site
1171376004563	H-loop/switch region; other site
1171376004564	cytochrome c-type protein NapC; Provisional; Region: PRK10617
1171376004565	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1171376004566	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
1171376004567	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1171376004568	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1171376004569	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1171376004570	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1171376004571	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1171376004572	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1171376004573	[4Fe-4S] binding site [ion binding]; other site
1171376004574	molybdopterin cofactor binding site; other site
1171376004575	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1171376004576	molybdopterin cofactor binding site; other site
1171376004577	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
1171376004578	ferredoxin-type protein; Provisional; Region: PRK10194
1171376004579	4Fe-4S binding domain; Region: Fer4; cl02805
1171376004580	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1171376004581	secondary substrate binding site; other site
1171376004582	primary substrate binding site; other site
1171376004583	inhibition loop; other site
1171376004584	dimerization interface [polypeptide binding]; other site
1171376004585	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1171376004586	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1171376004587	Walker A/P-loop; other site
1171376004588	ATP binding site [chemical binding]; other site
1171376004589	Q-loop/lid; other site
1171376004590	ABC transporter signature motif; other site
1171376004591	Walker B; other site
1171376004592	D-loop; other site
1171376004593	H-loop/switch region; other site
1171376004594	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1171376004595	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1171376004596	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1171376004597	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376004598	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1171376004599	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1171376004600	DNA binding site [nucleotide binding]
1171376004601	active site
1171376004602	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1171376004603	ApbE family; Region: ApbE; pfam02424
1171376004604	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1171376004605	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1171376004606	trimer interface [polypeptide binding]; other site
1171376004607	eyelet of channel; other site
1171376004608	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1171376004609	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376004610	ATP binding site [chemical binding]; other site
1171376004611	G-X-G motif; other site
1171376004612	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1171376004613	putative binding surface; other site
1171376004614	active site
1171376004615	transcriptional regulator RcsB; Provisional; Region: PRK10840
1171376004616	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376004617	active site
1171376004618	phosphorylation site [posttranslational modification]
1171376004619	intermolecular recognition site; other site
1171376004620	dimerization interface [polypeptide binding]; other site
1171376004621	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376004622	DNA binding residues [nucleotide binding]
1171376004623	dimerization interface [polypeptide binding]; other site
1171376004624	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1171376004625	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376004626	dimer interface [polypeptide binding]; other site
1171376004627	phosphorylation site [posttranslational modification]
1171376004628	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376004629	ATP binding site [chemical binding]; other site
1171376004630	Mg2+ binding site [ion binding]; other site
1171376004631	G-X-G motif; other site
1171376004632	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1171376004633	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376004634	active site
1171376004635	phosphorylation site [posttranslational modification]
1171376004636	intermolecular recognition site; other site
1171376004637	dimerization interface [polypeptide binding]; other site
1171376004638	DNA gyrase subunit A; Validated; Region: PRK05560
1171376004639	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1171376004640	CAP-like domain; other site
1171376004641	active site
1171376004642	primary dimer interface [polypeptide binding]; other site
1171376004643	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1171376004644	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1171376004645	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1171376004646	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1171376004647	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1171376004648	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1171376004649	phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396
1171376004650	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1171376004651	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1171376004652	active site pocket [active]
1171376004653	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1171376004654	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376004655	putative substrate translocation pore; other site
1171376004656	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1171376004657	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376004658	DNA-binding site [nucleotide binding]; DNA binding site
1171376004659	FCD domain; Region: FCD; pfam07729
1171376004660	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1171376004661	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376004662	S-adenosylmethionine binding site [chemical binding]; other site
1171376004663	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1171376004664	ATP cone domain; Region: ATP-cone; pfam03477
1171376004665	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1171376004666	active site
1171376004667	dimer interface [polypeptide binding]; other site
1171376004668	catalytic residues [active]
1171376004669	effector binding site; other site
1171376004670	R2 peptide binding site; other site
1171376004671	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1171376004672	dimer interface [polypeptide binding]; other site
1171376004673	putative radical transfer pathway; other site
1171376004674	diiron center [ion binding]; other site
1171376004675	tyrosyl radical; other site
1171376004676	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1171376004677	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1171376004678	catalytic loop [active]
1171376004679	iron binding site [ion binding]; other site
1171376004680	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1171376004681	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376004682	putative substrate translocation pore; other site
1171376004683	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
1171376004684	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376004685	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1171376004686	dimerization interface [polypeptide binding]; other site
1171376004687	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1171376004688	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1171376004689	active site
1171376004690	catalytic site [active]
1171376004691	metal binding site [ion binding]; metal-binding site
1171376004692	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1171376004693	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376004694	putative substrate translocation pore; other site
1171376004695	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1171376004696	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1171376004697	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1171376004698	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1171376004699	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1171376004700	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1171376004701	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1171376004702	Cysteine-rich domain; Region: CCG; pfam02754
1171376004703	Cysteine-rich domain; Region: CCG; pfam02754
1171376004704	deubiquitinase SseL; Provisional; Region: PRK14848
1171376004705	hypothetical protein; Provisional; Region: PRK03673
1171376004706	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
1171376004707	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376004708	D-galactonate transporter; Region: 2A0114; TIGR00893
1171376004709	putative substrate translocation pore; other site
1171376004710	L-rhamnonate dehydratase; Provisional; Region: PRK15440
1171376004711	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
1171376004712	putative active site pocket [active]
1171376004713	putative metal binding site [ion binding]; other site
1171376004714	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1171376004715	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1171376004716	Bacterial transcriptional regulator; Region: IclR; pfam01614
1171376004717	hypothetical protein; Provisional; Region: PRK03673
1171376004718	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1171376004719	putative MPT binding site; other site
1171376004720	Competence-damaged protein; Region: CinA; cl00666
1171376004721	YfaZ precursor; Region: YfaZ; pfam07437
1171376004722	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1171376004723	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1171376004724	catalytic core [active]
1171376004725	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1171376004726	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1171376004727	inhibitor-cofactor binding pocket; inhibition site
1171376004728	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376004729	catalytic residue [active]
1171376004730	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1171376004731	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1171376004732	Ligand binding site; other site
1171376004733	Putative Catalytic site; other site
1171376004734	DXD motif; other site
1171376004735	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1171376004736	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1171376004737	active site
1171376004738	substrate binding site [chemical binding]; other site
1171376004739	cosubstrate binding site; other site
1171376004740	catalytic site [active]
1171376004741	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1171376004742	active site
1171376004743	hexamer interface [polypeptide binding]; other site
1171376004744	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1171376004745	NAD binding site [chemical binding]; other site
1171376004746	substrate binding site [chemical binding]; other site
1171376004747	active site
1171376004748	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1171376004749	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1171376004750	putative active site [active]
1171376004751	putative catalytic site [active]
1171376004752	putative Zn binding site [ion binding]; other site
1171376004753	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1171376004754	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1171376004755	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1171376004756	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1171376004757	signal transduction protein PmrD; Provisional; Region: PRK15450
1171376004758	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1171376004759	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1171376004760	acyl-activating enzyme (AAE) consensus motif; other site
1171376004761	putative AMP binding site [chemical binding]; other site
1171376004762	putative active site [active]
1171376004763	putative CoA binding site [chemical binding]; other site
1171376004764	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
1171376004765	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1171376004766	active site
1171376004767	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1171376004768	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1171376004769	substrate binding site [chemical binding]; other site
1171376004770	oxyanion hole (OAH) forming residues; other site
1171376004771	trimer interface [polypeptide binding]; other site
1171376004772	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1171376004773	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1171376004774	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1171376004775	dimer interface [polypeptide binding]; other site
1171376004776	tetramer interface [polypeptide binding]; other site
1171376004777	PYR/PP interface [polypeptide binding]; other site
1171376004778	TPP binding site [chemical binding]; other site
1171376004779	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1171376004780	TPP-binding site; other site
1171376004781	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1171376004782	isochorismate synthases; Region: isochor_syn; TIGR00543
1171376004783	hypothetical protein; Provisional; Region: PRK10404
1171376004784	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376004785	Coenzyme A binding pocket [chemical binding]; other site
1171376004786	ribonuclease BN; Region: true_RNase_BN; TIGR02649
1171376004787	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1171376004788	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1171376004789	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376004790	active site
1171376004791	phosphorylation site [posttranslational modification]
1171376004792	intermolecular recognition site; other site
1171376004793	dimerization interface [polypeptide binding]; other site
1171376004794	von Willebrand factor; Region: vWF_A; pfam12450
1171376004795	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
1171376004796	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
1171376004797	metal ion-dependent adhesion site (MIDAS); other site
1171376004798	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
1171376004799	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
1171376004800	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1171376004801	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1171376004802	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1171376004803	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1171376004804	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1171376004805	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1171376004806	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1171376004807	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1171376004808	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1171376004809	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1171376004810	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1171376004811	4Fe-4S binding domain; Region: Fer4; pfam00037
1171376004812	4Fe-4S binding domain; Region: Fer4; pfam00037
1171376004813	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1171376004814	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1171376004815	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1171376004816	catalytic loop [active]
1171376004817	iron binding site [ion binding]; other site
1171376004818	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1171376004819	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1171376004820	[4Fe-4S] binding site [ion binding]; other site
1171376004821	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1171376004822	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1171376004823	SLBB domain; Region: SLBB; pfam10531
1171376004824	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1171376004825	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1171376004826	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1171376004827	putative dimer interface [polypeptide binding]; other site
1171376004828	[2Fe-2S] cluster binding site [ion binding]; other site
1171376004829	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1171376004830	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1171376004831	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1171376004832	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1171376004833	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1171376004834	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1171376004835	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376004836	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1171376004837	putative dimerization interface [polypeptide binding]; other site
1171376004838	aminotransferase AlaT; Validated; Region: PRK09265
1171376004839	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376004840	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376004841	homodimer interface [polypeptide binding]; other site
1171376004842	catalytic residue [active]
1171376004843	5'-nucleotidase; Provisional; Region: PRK03826
1171376004844	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1171376004845	transmembrane helices; other site
1171376004846	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1171376004847	TrkA-C domain; Region: TrkA_C; pfam02080
1171376004848	TrkA-C domain; Region: TrkA_C; pfam02080
1171376004849	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1171376004850	putative phosphatase; Provisional; Region: PRK11587
1171376004851	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376004852	motif II; other site
1171376004853	hypothetical protein; Validated; Region: PRK05445
1171376004854	hypothetical protein; Provisional; Region: PRK01816
1171376004855	propionate/acetate kinase; Provisional; Region: PRK12379
1171376004856	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1171376004857	phosphate acetyltransferase; Reviewed; Region: PRK05632
1171376004858	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1171376004859	DRTGG domain; Region: DRTGG; pfam07085
1171376004860	phosphate acetyltransferase; Region: pta; TIGR00651
1171376004861	hypothetical protein; Provisional; Region: PRK11588
1171376004862	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1171376004863	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1171376004864	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1171376004865	PYR/PP interface [polypeptide binding]; other site
1171376004866	dimer interface [polypeptide binding]; other site
1171376004867	TPP binding site [chemical binding]; other site
1171376004868	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1171376004869	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1171376004870	TPP-binding site [chemical binding]; other site
1171376004871	dimer interface [polypeptide binding]; other site
1171376004872	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
1171376004873	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1171376004874	active site
1171376004875	P-loop; other site
1171376004876	phosphorylation site [posttranslational modification]
1171376004877	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376004878	active site
1171376004879	phosphorylation site [posttranslational modification]
1171376004880	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1171376004881	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376004882	DNA binding site [nucleotide binding]
1171376004883	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1171376004884	putative dimerization interface [polypeptide binding]; other site
1171376004885	putative ligand binding site [chemical binding]; other site
1171376004886	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1171376004887	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1171376004888	nudix motif; other site
1171376004889	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1171376004890	active site
1171376004891	metal binding site [ion binding]; metal-binding site
1171376004892	homotetramer interface [polypeptide binding]; other site
1171376004893	glutathione S-transferase; Provisional; Region: PRK15113
1171376004894	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1171376004895	C-terminal domain interface [polypeptide binding]; other site
1171376004896	GSH binding site (G-site) [chemical binding]; other site
1171376004897	dimer interface [polypeptide binding]; other site
1171376004898	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1171376004899	N-terminal domain interface [polypeptide binding]; other site
1171376004900	putative dimer interface [polypeptide binding]; other site
1171376004901	putative substrate binding pocket (H-site) [chemical binding]; other site
1171376004902	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1171376004903	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1171376004904	C-terminal domain interface [polypeptide binding]; other site
1171376004905	GSH binding site (G-site) [chemical binding]; other site
1171376004906	dimer interface [polypeptide binding]; other site
1171376004907	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1171376004908	N-terminal domain interface [polypeptide binding]; other site
1171376004909	putative dimer interface [polypeptide binding]; other site
1171376004910	active site
1171376004911	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1171376004912	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1171376004913	putative NAD(P) binding site [chemical binding]; other site
1171376004914	putative active site [active]
1171376004915	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1171376004916	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1171376004917	Walker A/P-loop; other site
1171376004918	ATP binding site [chemical binding]; other site
1171376004919	Q-loop/lid; other site
1171376004920	ABC transporter signature motif; other site
1171376004921	Walker B; other site
1171376004922	D-loop; other site
1171376004923	H-loop/switch region; other site
1171376004924	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1171376004925	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376004926	dimer interface [polypeptide binding]; other site
1171376004927	conserved gate region; other site
1171376004928	putative PBP binding loops; other site
1171376004929	ABC-ATPase subunit interface; other site
1171376004930	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1171376004931	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376004932	dimer interface [polypeptide binding]; other site
1171376004933	conserved gate region; other site
1171376004934	putative PBP binding loops; other site
1171376004935	ABC-ATPase subunit interface; other site
1171376004936	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1171376004937	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376004938	substrate binding pocket [chemical binding]; other site
1171376004939	membrane-bound complex binding site; other site
1171376004940	hinge residues; other site
1171376004941	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1171376004942	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376004943	substrate binding pocket [chemical binding]; other site
1171376004944	membrane-bound complex binding site; other site
1171376004945	hinge residues; other site
1171376004946	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1171376004947	Flavoprotein; Region: Flavoprotein; pfam02441
1171376004948	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1171376004949	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
1171376004950	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
1171376004951	dimer interface [polypeptide binding]; other site
1171376004952	active site
1171376004953	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1171376004954	substrate binding site [chemical binding]; other site
1171376004955	catalytic residue [active]
1171376004956	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
1171376004957	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1171376004958	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1171376004959	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1171376004960	catalytic residue [active]
1171376004961	PAS fold; Region: PAS_4; pfam08448
1171376004962	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1171376004963	putative active site [active]
1171376004964	heme pocket [chemical binding]; other site
1171376004965	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1171376004966	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376004967	Walker A motif; other site
1171376004968	ATP binding site [chemical binding]; other site
1171376004969	Walker B motif; other site
1171376004970	arginine finger; other site
1171376004971	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1171376004972	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1171376004973	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1171376004974	active site
1171376004975	tetramer interface [polypeptide binding]; other site
1171376004976	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1171376004977	active site
1171376004978	colicin V production protein; Provisional; Region: PRK10845
1171376004979	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1171376004980	cell division protein DedD; Provisional; Region: PRK11633
1171376004981	Sporulation related domain; Region: SPOR; pfam05036
1171376004982	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1171376004983	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1171376004984	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1171376004985	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1171376004986	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1171376004987	hypothetical protein; Provisional; Region: PRK10847
1171376004988	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1171376004989	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
1171376004990	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1171376004991	dimerization interface 3.5A [polypeptide binding]; other site
1171376004992	active site
1171376004993	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1171376004994	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1171376004995	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1171376004996	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1171376004997	ligand binding site [chemical binding]; other site
1171376004998	NAD binding site [chemical binding]; other site
1171376004999	catalytic site [active]
1171376005000	homodimer interface [polypeptide binding]; other site
1171376005001	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1171376005002	putative transporter; Provisional; Region: PRK12382
1171376005003	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376005004	putative substrate translocation pore; other site
1171376005005	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376005006	non-specific DNA binding site [nucleotide binding]; other site
1171376005007	salt bridge; other site
1171376005008	sequence-specific DNA binding site [nucleotide binding]; other site
1171376005009	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1171376005010	CAAX protease self-immunity; Region: Abi; pfam02517
1171376005011	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1171376005012	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1171376005013	dimer interface [polypeptide binding]; other site
1171376005014	active site
1171376005015	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1171376005016	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1171376005017	YfcL protein; Region: YfcL; pfam08891
1171376005018	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
1171376005019	hypothetical protein; Provisional; Region: PRK10621
1171376005020	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1171376005021	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1171376005022	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1171376005023	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1171376005024	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1171376005025	Tetramer interface [polypeptide binding]; other site
1171376005026	active site
1171376005027	FMN-binding site [chemical binding]; other site
1171376005028	HemK family putative methylases; Region: hemK_fam; TIGR00536
1171376005029	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376005030	S-adenosylmethionine binding site [chemical binding]; other site
1171376005031	hypothetical protein; Provisional; Region: PRK04946
1171376005032	Smr domain; Region: Smr; pfam01713
1171376005033	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1171376005034	catalytic core [active]
1171376005035	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1171376005036	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1171376005037	substrate binding site [chemical binding]; other site
1171376005038	oxyanion hole (OAH) forming residues; other site
1171376005039	trimer interface [polypeptide binding]; other site
1171376005040	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1171376005041	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1171376005042	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1171376005043	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1171376005044	dimer interface [polypeptide binding]; other site
1171376005045	active site
1171376005046	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1171376005047	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1171376005048	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1171376005049	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1171376005050	outer membrane protease; Reviewed; Region: PRK10993
1171376005051	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1171376005052	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376005053	active site
1171376005054	phosphorylation site [posttranslational modification]
1171376005055	intermolecular recognition site; other site
1171376005056	dimerization interface [polypeptide binding]; other site
1171376005057	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1171376005058	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1171376005059	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
1171376005060	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1171376005061	dimerization interface [polypeptide binding]; other site
1171376005062	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376005063	dimer interface [polypeptide binding]; other site
1171376005064	phosphorylation site [posttranslational modification]
1171376005065	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376005066	ATP binding site [chemical binding]; other site
1171376005067	Mg2+ binding site [ion binding]; other site
1171376005068	G-X-G motif; other site
1171376005069	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1171376005070	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1171376005071	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1171376005072	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376005073	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376005074	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
1171376005075	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1171376005076	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1171376005077	putative acyl-acceptor binding pocket; other site
1171376005078	aminotransferase; Validated; Region: PRK08175
1171376005079	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376005080	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376005081	homodimer interface [polypeptide binding]; other site
1171376005082	catalytic residue [active]
1171376005083	glucokinase; Provisional; Region: glk; PRK00292
1171376005084	glucokinase, proteobacterial type; Region: glk; TIGR00749
1171376005085	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1171376005086	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1171376005087	Cl- selectivity filter; other site
1171376005088	Cl- binding residues [ion binding]; other site
1171376005089	pore gating glutamate residue; other site
1171376005090	dimer interface [polypeptide binding]; other site
1171376005091	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
1171376005092	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1171376005093	dimer interface [polypeptide binding]; other site
1171376005094	PYR/PP interface [polypeptide binding]; other site
1171376005095	TPP binding site [chemical binding]; other site
1171376005096	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1171376005097	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1171376005098	TPP-binding site [chemical binding]; other site
1171376005099	dimer interface [polypeptide binding]; other site
1171376005100	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1171376005101	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1171376005102	active site
1171376005103	catalytic tetrad [active]
1171376005104	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1171376005105	manganese transport protein MntH; Reviewed; Region: PRK00701
1171376005106	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1171376005107	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1171376005108	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1171376005109	Nucleoside recognition; Region: Gate; pfam07670
1171376005110	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1171376005111	MASE1; Region: MASE1; pfam05231
1171376005112	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1171376005113	diguanylate cyclase; Region: GGDEF; smart00267
1171376005114	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376005115	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1171376005116	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1171376005117	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1171376005118	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1171376005119	active site
1171376005120	HIGH motif; other site
1171376005121	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1171376005122	active site
1171376005123	KMSKS motif; other site
1171376005124	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1171376005125	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376005126	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
1171376005127	putative dimerization interface [polypeptide binding]; other site
1171376005128	putative substrate binding pocket [chemical binding]; other site
1171376005129	XapX domain; Region: XapX; TIGR03510
1171376005130	nucleoside transporter; Region: 2A0110; TIGR00889
1171376005131	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376005132	putative substrate translocation pore; other site
1171376005133	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1171376005134	hypothetical protein; Provisional; Region: PRK11528
1171376005135	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376005136	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376005137	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1171376005138	putative dimerization interface [polypeptide binding]; other site
1171376005139	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1171376005140	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1171376005141	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1171376005142	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1171376005143	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1171376005144	nucleotide binding pocket [chemical binding]; other site
1171376005145	K-X-D-G motif; other site
1171376005146	catalytic site [active]
1171376005147	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1171376005148	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1171376005149	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1171376005150	Dimer interface [polypeptide binding]; other site
1171376005151	BRCT sequence motif; other site
1171376005152	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
1171376005153	cell division protein ZipA; Provisional; Region: PRK03427
1171376005154	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1171376005155	FtsZ protein binding site [polypeptide binding]; other site
1171376005156	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1171376005157	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1171376005158	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1171376005159	dimer interface [polypeptide binding]; other site
1171376005160	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376005161	catalytic residue [active]
1171376005162	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1171376005163	dimerization domain swap beta strand [polypeptide binding]; other site
1171376005164	regulatory protein interface [polypeptide binding]; other site
1171376005165	active site
1171376005166	regulatory phosphorylation site [posttranslational modification]; other site
1171376005167	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1171376005168	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1171376005169	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1171376005170	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1171376005171	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1171376005172	HPr interaction site; other site
1171376005173	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1171376005174	active site
1171376005175	phosphorylation site [posttranslational modification]
1171376005176	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1171376005177	dimer interface [polypeptide binding]; other site
1171376005178	pyridoxamine kinase; Validated; Region: PRK05756
1171376005179	pyridoxal binding site [chemical binding]; other site
1171376005180	ATP binding site [chemical binding]; other site
1171376005181	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
1171376005182	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376005183	DNA-binding site [nucleotide binding]; DNA binding site
1171376005184	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376005185	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376005186	homodimer interface [polypeptide binding]; other site
1171376005187	catalytic residue [active]
1171376005188	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1171376005189	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1171376005190	catalytic triad [active]
1171376005191	hypothetical protein; Provisional; Region: PRK10318
1171376005192	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
1171376005193	Transglycosylase; Region: Transgly; cl17702
1171376005194	cysteine synthase B; Region: cysM; TIGR01138
1171376005195	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1171376005196	dimer interface [polypeptide binding]; other site
1171376005197	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376005198	catalytic residue [active]
1171376005199	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1171376005200	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1171376005201	Walker A/P-loop; other site
1171376005202	ATP binding site [chemical binding]; other site
1171376005203	Q-loop/lid; other site
1171376005204	ABC transporter signature motif; other site
1171376005205	Walker B; other site
1171376005206	D-loop; other site
1171376005207	H-loop/switch region; other site
1171376005208	TOBE-like domain; Region: TOBE_3; pfam12857
1171376005209	sulfate transport protein; Provisional; Region: cysT; CHL00187
1171376005210	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376005211	dimer interface [polypeptide binding]; other site
1171376005212	conserved gate region; other site
1171376005213	putative PBP binding loops; other site
1171376005214	ABC-ATPase subunit interface; other site
1171376005215	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1171376005216	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376005217	dimer interface [polypeptide binding]; other site
1171376005218	conserved gate region; other site
1171376005219	putative PBP binding loops; other site
1171376005220	ABC-ATPase subunit interface; other site
1171376005221	thiosulfate transporter subunit; Provisional; Region: PRK10852
1171376005222	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1171376005223	short chain dehydrogenase; Provisional; Region: PRK08226
1171376005224	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
1171376005225	NAD binding site [chemical binding]; other site
1171376005226	homotetramer interface [polypeptide binding]; other site
1171376005227	homodimer interface [polypeptide binding]; other site
1171376005228	active site
1171376005229	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1171376005230	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1171376005231	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1171376005232	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1171376005233	putative acetyltransferase; Provisional; Region: PRK03624
1171376005234	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376005235	Coenzyme A binding pocket [chemical binding]; other site
1171376005236	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1171376005237	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1171376005238	active site
1171376005239	metal binding site [ion binding]; metal-binding site
1171376005240	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1171376005241	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1171376005242	transcriptional regulator EutR; Provisional; Region: PRK10130
1171376005243	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376005244	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376005245	carboxysome structural protein EutK; Provisional; Region: PRK15466
1171376005246	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1171376005247	Hexamer interface [polypeptide binding]; other site
1171376005248	Hexagonal pore residue; other site
1171376005249	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1171376005250	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
1171376005251	putative hexamer interface [polypeptide binding]; other site
1171376005252	putative hexagonal pore; other site
1171376005253	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1171376005254	putative hexamer interface [polypeptide binding]; other site
1171376005255	putative hexagonal pore; other site
1171376005256	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1171376005257	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1171376005258	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1171376005259	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
1171376005260	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
1171376005261	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
1171376005262	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1171376005263	active site
1171376005264	metal binding site [ion binding]; metal-binding site
1171376005265	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
1171376005266	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1171376005267	nucleotide binding site [chemical binding]; other site
1171376005268	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1171376005269	putative catalytic cysteine [active]
1171376005270	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1171376005271	Hexamer/Pentamer interface [polypeptide binding]; other site
1171376005272	central pore; other site
1171376005273	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1171376005274	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1171376005275	Hexamer interface [polypeptide binding]; other site
1171376005276	Putative hexagonal pore residue; other site
1171376005277	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1171376005278	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
1171376005279	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1171376005280	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
1171376005281	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1171376005282	G1 box; other site
1171376005283	GTP/Mg2+ binding site [chemical binding]; other site
1171376005284	G2 box; other site
1171376005285	Switch I region; other site
1171376005286	G3 box; other site
1171376005287	Switch II region; other site
1171376005288	G4 box; other site
1171376005289	G5 box; other site
1171376005290	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1171376005291	putative hexamer interface [polypeptide binding]; other site
1171376005292	putative hexagonal pore; other site
1171376005293	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1171376005294	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1171376005295	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1171376005296	putative NAD(P) binding site [chemical binding]; other site
1171376005297	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1171376005298	transaldolase-like protein; Provisional; Region: PTZ00411
1171376005299	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1171376005300	active site
1171376005301	dimer interface [polypeptide binding]; other site
1171376005302	catalytic residue [active]
1171376005303	transketolase; Reviewed; Region: PRK12753
1171376005304	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1171376005305	TPP-binding site [chemical binding]; other site
1171376005306	dimer interface [polypeptide binding]; other site
1171376005307	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1171376005308	PYR/PP interface [polypeptide binding]; other site
1171376005309	dimer interface [polypeptide binding]; other site
1171376005310	TPP binding site [chemical binding]; other site
1171376005311	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1171376005312	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1171376005313	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1171376005314	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1171376005315	dimer interface [polypeptide binding]; other site
1171376005316	ADP-ribose binding site [chemical binding]; other site
1171376005317	active site
1171376005318	nudix motif; other site
1171376005319	metal binding site [ion binding]; metal-binding site
1171376005320	putative periplasmic esterase; Provisional; Region: PRK03642
1171376005321	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1171376005322	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1171376005323	4Fe-4S binding domain; Region: Fer4; pfam00037
1171376005324	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1171376005325	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376005326	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1171376005327	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1171376005328	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376005329	dimerization interface [polypeptide binding]; other site
1171376005330	Histidine kinase; Region: HisKA_3; pfam07730
1171376005331	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376005332	ATP binding site [chemical binding]; other site
1171376005333	Mg2+ binding site [ion binding]; other site
1171376005334	G-X-G motif; other site
1171376005335	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1171376005336	Protein export membrane protein; Region: SecD_SecF; cl14618
1171376005337	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1171376005338	ArsC family; Region: ArsC; pfam03960
1171376005339	putative catalytic residues [active]
1171376005340	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1171376005341	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1171376005342	metal binding site [ion binding]; metal-binding site
1171376005343	dimer interface [polypeptide binding]; other site
1171376005344	hypothetical protein; Provisional; Region: PRK13664
1171376005345	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1171376005346	Helicase; Region: Helicase_RecD; pfam05127
1171376005347	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1171376005348	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1171376005349	Predicted metalloprotease [General function prediction only]; Region: COG2321
1171376005350	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1171376005351	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1171376005352	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1171376005353	ATP binding site [chemical binding]; other site
1171376005354	active site
1171376005355	substrate binding site [chemical binding]; other site
1171376005356	lipoprotein; Provisional; Region: PRK11679
1171376005357	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1171376005358	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1171376005359	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1171376005360	dimer interface [polypeptide binding]; other site
1171376005361	active site
1171376005362	catalytic residue [active]
1171376005363	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1171376005364	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1171376005365	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1171376005366	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1171376005367	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1171376005368	catalytic triad [active]
1171376005369	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1171376005370	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1171376005371	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1171376005372	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1171376005373	Peptidase family M48; Region: Peptidase_M48; cl12018
1171376005374	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1171376005375	ArsC family; Region: ArsC; pfam03960
1171376005376	catalytic residues [active]
1171376005377	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1171376005378	DNA replication initiation factor; Provisional; Region: PRK08084
1171376005379	uracil transporter; Provisional; Region: PRK10720
1171376005380	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1171376005381	active site
1171376005382	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1171376005383	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1171376005384	dimerization interface [polypeptide binding]; other site
1171376005385	putative ATP binding site [chemical binding]; other site
1171376005386	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1171376005387	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1171376005388	active site
1171376005389	substrate binding site [chemical binding]; other site
1171376005390	cosubstrate binding site; other site
1171376005391	catalytic site [active]
1171376005392	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1171376005393	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1171376005394	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1171376005395	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1171376005396	putative active site [active]
1171376005397	catalytic site [active]
1171376005398	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1171376005399	domain interface [polypeptide binding]; other site
1171376005400	active site
1171376005401	catalytic site [active]
1171376005402	exopolyphosphatase; Provisional; Region: PRK10854
1171376005403	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1171376005404	nucleotide binding site [chemical binding]; other site
1171376005405	MASE1; Region: MASE1; pfam05231
1171376005406	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1171376005407	diguanylate cyclase; Region: GGDEF; smart00267
1171376005408	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376005409	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1171376005410	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1171376005411	Integrase core domain; Region: rve; pfam00665
1171376005412	GMP synthase; Reviewed; Region: guaA; PRK00074
1171376005413	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1171376005414	AMP/PPi binding site [chemical binding]; other site
1171376005415	candidate oxyanion hole; other site
1171376005416	catalytic triad [active]
1171376005417	potential glutamine specificity residues [chemical binding]; other site
1171376005418	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1171376005419	ATP Binding subdomain [chemical binding]; other site
1171376005420	Ligand Binding sites [chemical binding]; other site
1171376005421	Dimerization subdomain; other site
1171376005422	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1171376005423	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1171376005424	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1171376005425	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1171376005426	active site
1171376005427	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1171376005428	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1171376005429	generic binding surface II; other site
1171376005430	generic binding surface I; other site
1171376005431	AIDA autotransporter-like protein ShdA; Provisional; Region: PRK15319
1171376005432	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1171376005433	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1171376005434	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1171376005435	Autotransporter beta-domain; Region: Autotransporter; smart00869
1171376005436	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1171376005437	outer membrane protein RatB; Provisional; Region: PRK15314
1171376005438	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005439	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005440	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005441	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005442	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005443	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005444	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005445	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005446	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005447	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005448	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005449	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005450	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005451	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005452	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005453	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005454	outer membrane protein RatA; Provisional; Region: PRK15315
1171376005455	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005456	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005457	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005458	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005459	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005460	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005461	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005462	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005463	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005464	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1171376005465	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1171376005466	intimin-like protein SinH; Provisional; Region: PRK15318
1171376005467	intimin-like protein SinH; Provisional; Region: PRK15318
1171376005468	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1171376005469	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1171376005470	GTP-binding protein Der; Reviewed; Region: PRK00093
1171376005471	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1171376005472	G1 box; other site
1171376005473	GTP/Mg2+ binding site [chemical binding]; other site
1171376005474	Switch I region; other site
1171376005475	G2 box; other site
1171376005476	Switch II region; other site
1171376005477	G3 box; other site
1171376005478	G4 box; other site
1171376005479	G5 box; other site
1171376005480	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1171376005481	G1 box; other site
1171376005482	GTP/Mg2+ binding site [chemical binding]; other site
1171376005483	Switch I region; other site
1171376005484	G2 box; other site
1171376005485	G3 box; other site
1171376005486	Switch II region; other site
1171376005487	G4 box; other site
1171376005488	G5 box; other site
1171376005489	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1171376005490	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
1171376005491	Trp docking motif [polypeptide binding]; other site
1171376005492	active site
1171376005493	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1171376005494	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1171376005495	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1171376005496	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1171376005497	dimer interface [polypeptide binding]; other site
1171376005498	motif 1; other site
1171376005499	active site
1171376005500	motif 2; other site
1171376005501	motif 3; other site
1171376005502	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1171376005503	anticodon binding site; other site
1171376005504	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1171376005505	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1171376005506	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1171376005507	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1171376005508	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376005509	non-specific DNA binding site [nucleotide binding]; other site
1171376005510	salt bridge; other site
1171376005511	sequence-specific DNA binding site [nucleotide binding]; other site
1171376005512	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1171376005513	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1171376005514	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376005515	FeS/SAM binding site; other site
1171376005516	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1171376005517	active site
1171376005518	multimer interface [polypeptide binding]; other site
1171376005519	4Fe-4S binding domain; Region: Fer4; pfam00037
1171376005520	hydrogenase 4 subunit H; Validated; Region: PRK08222
1171376005521	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1171376005522	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1171376005523	4Fe-4S binding domain; Region: Fer4; pfam00037
1171376005524	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1171376005525	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1171376005526	putative [Fe4-S4] binding site [ion binding]; other site
1171376005527	putative molybdopterin cofactor binding site [chemical binding]; other site
1171376005528	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1171376005529	putative molybdopterin cofactor binding site; other site
1171376005530	penicillin-binding protein 1C; Provisional; Region: PRK11240
1171376005531	Transglycosylase; Region: Transgly; pfam00912
1171376005532	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1171376005533	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1171376005534	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1171376005535	MG2 domain; Region: A2M_N; pfam01835
1171376005536	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1171376005537	surface patch; other site
1171376005538	thioester region; other site
1171376005539	specificity defining residues; other site
1171376005540	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1171376005541	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1171376005542	active site residue [active]
1171376005543	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1171376005544	active site residue [active]
1171376005545	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1171376005546	aminopeptidase B; Provisional; Region: PRK05015
1171376005547	Peptidase; Region: DUF3663; pfam12404
1171376005548	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1171376005549	interface (dimer of trimers) [polypeptide binding]; other site
1171376005550	Substrate-binding/catalytic site; other site
1171376005551	Zn-binding sites [ion binding]; other site
1171376005552	hypothetical protein; Provisional; Region: PRK10721
1171376005553	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1171376005554	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1171376005555	catalytic loop [active]
1171376005556	iron binding site [ion binding]; other site
1171376005557	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1171376005558	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1171376005559	nucleotide binding site [chemical binding]; other site
1171376005560	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1171376005561	SBD interface [polypeptide binding]; other site
1171376005562	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1171376005563	DnaJ domain; Region: DnaJ; pfam00226
1171376005564	HSP70 interaction site [polypeptide binding]; other site
1171376005565	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1171376005566	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1171376005567	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1171376005568	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1171376005569	trimerization site [polypeptide binding]; other site
1171376005570	active site
1171376005571	cysteine desulfurase; Provisional; Region: PRK14012
1171376005572	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1171376005573	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1171376005574	catalytic residue [active]
1171376005575	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1171376005576	Rrf2 family protein; Region: rrf2_super; TIGR00738
1171376005577	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1171376005578	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1171376005579	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1171376005580	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1171376005581	active site
1171376005582	dimerization interface [polypeptide binding]; other site
1171376005583	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1171376005584	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1171376005585	sulfite reductase, subunit A; Region: sulfite_red_A; TIGR02910
1171376005586	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1171376005587	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
1171376005588	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
1171376005589	FAD binding pocket [chemical binding]; other site
1171376005590	FAD binding motif [chemical binding]; other site
1171376005591	phosphate binding motif [ion binding]; other site
1171376005592	beta-alpha-beta structure motif; other site
1171376005593	NAD binding pocket [chemical binding]; other site
1171376005594	Iron coordination center [ion binding]; other site
1171376005595	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
1171376005596	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1171376005597	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1171376005598	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1171376005599	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
1171376005600	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1171376005601	PRD domain; Region: PRD; pfam00874
1171376005602	PRD domain; Region: PRD; pfam00874
1171376005603	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1171376005604	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376005605	putative substrate translocation pore; other site
1171376005606	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1171376005607	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1171376005608	dimer interface [polypeptide binding]; other site
1171376005609	active site
1171376005610	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1171376005611	folate binding site [chemical binding]; other site
1171376005612	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1171376005613	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1171376005614	heme-binding site [chemical binding]; other site
1171376005615	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1171376005616	FAD binding pocket [chemical binding]; other site
1171376005617	FAD binding motif [chemical binding]; other site
1171376005618	phosphate binding motif [ion binding]; other site
1171376005619	beta-alpha-beta structure motif; other site
1171376005620	NAD binding pocket [chemical binding]; other site
1171376005621	Heme binding  pocket [chemical binding]; other site
1171376005622	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
1171376005623	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376005624	DNA binding site [nucleotide binding]
1171376005625	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
1171376005626	lysine decarboxylase CadA; Provisional; Region: PRK15400
1171376005627	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1171376005628	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1171376005629	homodimer interface [polypeptide binding]; other site
1171376005630	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376005631	catalytic residue [active]
1171376005632	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1171376005633	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1171376005634	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376005635	putative substrate translocation pore; other site
1171376005636	POT family; Region: PTR2; pfam00854
1171376005637	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1171376005638	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1171376005639	response regulator GlrR; Provisional; Region: PRK15115
1171376005640	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376005641	active site
1171376005642	phosphorylation site [posttranslational modification]
1171376005643	intermolecular recognition site; other site
1171376005644	dimerization interface [polypeptide binding]; other site
1171376005645	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376005646	Walker A motif; other site
1171376005647	ATP binding site [chemical binding]; other site
1171376005648	Walker B motif; other site
1171376005649	arginine finger; other site
1171376005650	hypothetical protein; Provisional; Region: PRK10722
1171376005651	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1171376005652	HAMP domain; Region: HAMP; pfam00672
1171376005653	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376005654	dimer interface [polypeptide binding]; other site
1171376005655	phosphorylation site [posttranslational modification]
1171376005656	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376005657	ATP binding site [chemical binding]; other site
1171376005658	Mg2+ binding site [ion binding]; other site
1171376005659	G-X-G motif; other site
1171376005660	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1171376005661	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1171376005662	dimerization interface [polypeptide binding]; other site
1171376005663	ATP binding site [chemical binding]; other site
1171376005664	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
1171376005665	dimerization interface [polypeptide binding]; other site
1171376005666	ATP binding site [chemical binding]; other site
1171376005667	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1171376005668	putative active site [active]
1171376005669	catalytic triad [active]
1171376005670	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1171376005671	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376005672	substrate binding pocket [chemical binding]; other site
1171376005673	membrane-bound complex binding site; other site
1171376005674	hinge residues; other site
1171376005675	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1171376005676	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1171376005677	catalytic residue [active]
1171376005678	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1171376005679	nucleoside/Zn binding site; other site
1171376005680	dimer interface [polypeptide binding]; other site
1171376005681	catalytic motif [active]
1171376005682	hypothetical protein; Provisional; Region: PRK11590
1171376005683	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1171376005684	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1171376005685	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1171376005686	active site turn [active]
1171376005687	phosphorylation site [posttranslational modification]
1171376005688	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1171376005689	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1171376005690	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1171376005691	putative active site [active]
1171376005692	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1171376005693	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1171376005694	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1171376005695	putative active site [active]
1171376005696	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1171376005697	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1171376005698	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1171376005699	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1171376005700	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376005701	putative substrate translocation pore; other site
1171376005702	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376005703	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376005704	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1171376005705	dimerization interface [polypeptide binding]; other site
1171376005706	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1171376005707	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1171376005708	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1171376005709	active site
1171376005710	hydrophilic channel; other site
1171376005711	dimerization interface [polypeptide binding]; other site
1171376005712	catalytic residues [active]
1171376005713	active site lid [active]
1171376005714	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1171376005715	Recombination protein O N terminal; Region: RecO_N; pfam11967
1171376005716	Recombination protein O C terminal; Region: RecO_C; pfam02565
1171376005717	GTPase Era; Reviewed; Region: era; PRK00089
1171376005718	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1171376005719	G1 box; other site
1171376005720	GTP/Mg2+ binding site [chemical binding]; other site
1171376005721	Switch I region; other site
1171376005722	G2 box; other site
1171376005723	Switch II region; other site
1171376005724	G3 box; other site
1171376005725	G4 box; other site
1171376005726	G5 box; other site
1171376005727	KH domain; Region: KH_2; pfam07650
1171376005728	ribonuclease III; Reviewed; Region: rnc; PRK00102
1171376005729	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1171376005730	dimerization interface [polypeptide binding]; other site
1171376005731	active site
1171376005732	metal binding site [ion binding]; metal-binding site
1171376005733	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1171376005734	dsRNA binding site [nucleotide binding]; other site
1171376005735	signal peptidase I; Provisional; Region: PRK10861
1171376005736	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1171376005737	Catalytic site [active]
1171376005738	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1171376005739	GTP-binding protein LepA; Provisional; Region: PRK05433
1171376005740	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1171376005741	G1 box; other site
1171376005742	putative GEF interaction site [polypeptide binding]; other site
1171376005743	GTP/Mg2+ binding site [chemical binding]; other site
1171376005744	Switch I region; other site
1171376005745	G2 box; other site
1171376005746	G3 box; other site
1171376005747	Switch II region; other site
1171376005748	G4 box; other site
1171376005749	G5 box; other site
1171376005750	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1171376005751	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1171376005752	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1171376005753	type III secretion protein GogB; Provisional; Region: PRK15386
1171376005754	Integrase core domain; Region: rve_3; cl15866
1171376005755	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
1171376005756	DNA-binding interface [nucleotide binding]; DNA binding site
1171376005757	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1171376005758	Macro domain, Appr-1"-pase family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Appr_pase; cd02900
1171376005759	ADP-ribose binding site [chemical binding]; other site
1171376005760	putative active site [active]
1171376005761	dimer interface [polypeptide binding]; other site
1171376005762	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1171376005763	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1171376005764	Phage Tail Collar Domain; Region: Collar; pfam07484
1171376005765	Phage-related protein, tail component [Function unknown]; Region: COG4733
1171376005766	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1171376005767	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1171376005768	Interdomain contacts; other site
1171376005769	Cytokine receptor motif; other site
1171376005770	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1171376005771	Fibronectin type III protein; Region: DUF3672; pfam12421
1171376005772	Phage-related protein, tail component [Function unknown]; Region: COG4723
1171376005773	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1171376005774	MPN+ (JAMM) motif; other site
1171376005775	Zinc-binding site [ion binding]; other site
1171376005776	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1171376005777	NlpC/P60 family; Region: NLPC_P60; cl17555
1171376005778	Phage-related protein [Function unknown]; Region: gp18; COG4672
1171376005779	Phage-related protein [Function unknown]; Region: COG4718
1171376005780	Phage-related minor tail protein [Function unknown]; Region: COG5281
1171376005781	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1171376005782	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1171376005783	Minor tail protein T; Region: Phage_tail_T; pfam06223
1171376005784	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
1171376005785	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1171376005786	Phage tail protein; Region: Phage_tail_3; pfam08813
1171376005787	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1171376005788	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1171376005789	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1171376005790	Probable transposase; Region: OrfB_IS605; pfam01385
1171376005791	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1171376005792	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1171376005793	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; cl05094
1171376005794	DNA packaging protein FI; Region: Packaging_FI; pfam14000
1171376005795	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1171376005796	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
1171376005797	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1171376005798	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1171376005799	tandem repeat interface [polypeptide binding]; other site
1171376005800	oligomer interface [polypeptide binding]; other site
1171376005801	active site residues [active]
1171376005802	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1171376005803	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1171376005804	gpW; Region: gpW; pfam02831
1171376005805	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1171376005806	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
1171376005807	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
1171376005808	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1171376005809	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1171376005810	catalytic residues [active]
1171376005811	phage holin, lambda family; Region: holin_lambda; TIGR01594
1171376005812	PipA protein; Region: PipA; pfam07108
1171376005813	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1171376005814	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1171376005815	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1171376005816	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1171376005817	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1171376005818	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1171376005819	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1171376005820	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1171376005821	Transposase; Region: HTH_Tnp_1; pfam01527
1171376005822	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1171376005823	ORF6N domain; Region: ORF6N; pfam10543
1171376005824	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
1171376005825	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1171376005826	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1171376005827	DinI-like family; Region: DinI; pfam06183
1171376005828	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1171376005829	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1171376005830	putative replication protein; Provisional; Region: PRK12377
1171376005831	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376005832	Walker A motif; other site
1171376005833	ATP binding site [chemical binding]; other site
1171376005834	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1171376005835	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1171376005836	primosomal protein DnaI; Provisional; Region: PRK02854
1171376005837	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1171376005838	DNA binding residues [nucleotide binding]
1171376005839	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376005840	non-specific DNA binding site [nucleotide binding]; other site
1171376005841	salt bridge; other site
1171376005842	sequence-specific DNA binding site [nucleotide binding]; other site
1171376005843	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1171376005844	exonuclease VIII; Reviewed; Region: PRK09709
1171376005845	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
1171376005846	RecT family; Region: RecT; pfam03837
1171376005847	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
1171376005848	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1171376005849	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1171376005850	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1171376005851	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
1171376005852	Int/Topo IB signature motif; other site
1171376005853	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1171376005854	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1171376005855	active site
1171376005856	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1171376005857	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1171376005858	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1171376005859	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
1171376005860	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1171376005861	catalytic residue [active]
1171376005862	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1171376005863	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1171376005864	putative DNA binding site [nucleotide binding]; other site
1171376005865	putative Zn2+ binding site [ion binding]; other site
1171376005866	AsnC family; Region: AsnC_trans_reg; pfam01037
1171376005867	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1171376005868	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1171376005869	putative dimer interface [polypeptide binding]; other site
1171376005870	putative anticodon binding site; other site
1171376005871	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1171376005872	homodimer interface [polypeptide binding]; other site
1171376005873	motif 1; other site
1171376005874	motif 2; other site
1171376005875	active site
1171376005876	motif 3; other site
1171376005877	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1171376005878	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1171376005879	trimer interface [polypeptide binding]; other site
1171376005880	eyelet of channel; other site
1171376005881	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1171376005882	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376005883	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376005884	homodimer interface [polypeptide binding]; other site
1171376005885	catalytic residue [active]
1171376005886	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1171376005887	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1171376005888	Peptidase M15; Region: Peptidase_M15_3; cl01194
1171376005889	murein L,D-transpeptidase; Provisional; Region: PRK10594
1171376005890	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1171376005891	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1171376005892	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1171376005893	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
1171376005894	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1171376005895	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1171376005896	condesin subunit E; Provisional; Region: PRK05256
1171376005897	condesin subunit F; Provisional; Region: PRK05260
1171376005898	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1171376005899	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376005900	S-adenosylmethionine binding site [chemical binding]; other site
1171376005901	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1171376005902	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1171376005903	putative active site [active]
1171376005904	hypothetical protein; Provisional; Region: PRK10593
1171376005905	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1171376005906	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1171376005907	Ligand binding site; other site
1171376005908	oligomer interface; other site
1171376005909	hypothetical protein; Provisional; Region: PRK11827
1171376005910	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
1171376005911	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1171376005912	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1171376005913	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1171376005914	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1171376005915	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1171376005916	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1171376005917	Walker A/P-loop; other site
1171376005918	ATP binding site [chemical binding]; other site
1171376005919	Q-loop/lid; other site
1171376005920	ABC transporter signature motif; other site
1171376005921	Walker B; other site
1171376005922	D-loop; other site
1171376005923	H-loop/switch region; other site
1171376005924	ComEC family competence protein; Provisional; Region: PRK11539
1171376005925	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1171376005926	Competence protein; Region: Competence; pfam03772
1171376005927	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1171376005928	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1171376005929	IHF dimer interface [polypeptide binding]; other site
1171376005930	IHF - DNA interface [nucleotide binding]; other site
1171376005931	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1171376005932	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1171376005933	RNA binding site [nucleotide binding]; other site
1171376005934	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1171376005935	RNA binding site [nucleotide binding]; other site
1171376005936	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1171376005937	RNA binding site [nucleotide binding]; other site
1171376005938	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1171376005939	RNA binding site [nucleotide binding]; other site
1171376005940	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1171376005941	RNA binding site [nucleotide binding]; other site
1171376005942	cytidylate kinase; Provisional; Region: cmk; PRK00023
1171376005943	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1171376005944	CMP-binding site; other site
1171376005945	The sites determining sugar specificity; other site
1171376005946	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1171376005947	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1171376005948	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
1171376005949	hinge; other site
1171376005950	active site
1171376005951	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1171376005952	homodimer interface [polypeptide binding]; other site
1171376005953	substrate-cofactor binding pocket; other site
1171376005954	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376005955	catalytic residue [active]
1171376005956	Predicted membrane protein [Function unknown]; Region: COG2323
1171376005957	uncharacterized domain; Region: TIGR00702
1171376005958	YcaO-like family; Region: YcaO; pfam02624
1171376005959	formate transporter; Provisional; Region: PRK10805
1171376005960	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1171376005961	Pyruvate formate lyase 1; Region: PFL1; cd01678
1171376005962	coenzyme A binding site [chemical binding]; other site
1171376005963	active site
1171376005964	catalytic residues [active]
1171376005965	glycine loop; other site
1171376005966	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
1171376005967	integrase; Provisional; Region: int; PHA02601
1171376005968	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1171376005969	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376005970	FeS/SAM binding site; other site
1171376005971	inner membrane transporter YjeM; Provisional; Region: PRK15238
1171376005972	putative MFS family transporter protein; Provisional; Region: PRK03633
1171376005973	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376005974	putative substrate translocation pore; other site
1171376005975	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1171376005976	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1171376005977	4Fe-4S binding domain; Region: Fer4; pfam00037
1171376005978	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1171376005979	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1171376005980	putative [Fe4-S4] binding site [ion binding]; other site
1171376005981	putative molybdopterin cofactor binding site [chemical binding]; other site
1171376005982	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1171376005983	putative molybdopterin cofactor binding site; other site
1171376005984	seryl-tRNA synthetase; Provisional; Region: PRK05431
1171376005985	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1171376005986	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1171376005987	dimer interface [polypeptide binding]; other site
1171376005988	active site
1171376005989	motif 1; other site
1171376005990	motif 2; other site
1171376005991	motif 3; other site
1171376005992	recombination factor protein RarA; Reviewed; Region: PRK13342
1171376005993	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376005994	Walker A motif; other site
1171376005995	ATP binding site [chemical binding]; other site
1171376005996	Walker B motif; other site
1171376005997	arginine finger; other site
1171376005998	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1171376005999	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1171376006000	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1171376006001	DNA translocase FtsK; Provisional; Region: PRK10263
1171376006002	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1171376006003	DNA translocase FtsK; Provisional; Region: PRK10263
1171376006004	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1171376006005	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1171376006006	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1171376006007	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1171376006008	putative DNA binding site [nucleotide binding]; other site
1171376006009	putative Zn2+ binding site [ion binding]; other site
1171376006010	AsnC family; Region: AsnC_trans_reg; pfam01037
1171376006011	thioredoxin reductase; Provisional; Region: PRK10262
1171376006012	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1171376006013	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376006014	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1171376006015	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1171376006016	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376006017	Walker A/P-loop; other site
1171376006018	ATP binding site [chemical binding]; other site
1171376006019	Q-loop/lid; other site
1171376006020	ABC transporter signature motif; other site
1171376006021	Walker B; other site
1171376006022	D-loop; other site
1171376006023	H-loop/switch region; other site
1171376006024	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1171376006025	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1171376006026	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376006027	Walker A/P-loop; other site
1171376006028	ATP binding site [chemical binding]; other site
1171376006029	Q-loop/lid; other site
1171376006030	ABC transporter signature motif; other site
1171376006031	Walker B; other site
1171376006032	D-loop; other site
1171376006033	H-loop/switch region; other site
1171376006034	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1171376006035	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1171376006036	rRNA binding site [nucleotide binding]; other site
1171376006037	predicted 30S ribosome binding site; other site
1171376006038	LysR family transcriptional regulator; Provisional; Region: PRK14997
1171376006039	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376006040	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
1171376006041	putative effector binding pocket; other site
1171376006042	putative dimerization interface [polypeptide binding]; other site
1171376006043	Pirin-related protein [General function prediction only]; Region: COG1741
1171376006044	Pirin; Region: Pirin; pfam02678
1171376006045	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1171376006046	Isochorismatase family; Region: Isochorismatase; pfam00857
1171376006047	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1171376006048	catalytic triad [active]
1171376006049	dimer interface [polypeptide binding]; other site
1171376006050	conserved cis-peptide bond; other site
1171376006051	Helix-turn-helix domain; Region: HTH_28; pfam13518
1171376006052	Integrase core domain; Region: rve; pfam00665
1171376006053	Integrase core domain; Region: rve_3; pfam13683
1171376006054	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1171376006055	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1171376006056	Clp amino terminal domain; Region: Clp_N; pfam02861
1171376006057	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376006058	Walker A motif; other site
1171376006059	ATP binding site [chemical binding]; other site
1171376006060	Walker B motif; other site
1171376006061	arginine finger; other site
1171376006062	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376006063	Walker A motif; other site
1171376006064	ATP binding site [chemical binding]; other site
1171376006065	Walker B motif; other site
1171376006066	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1171376006067	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1171376006068	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1171376006069	DNA-binding site [nucleotide binding]; DNA binding site
1171376006070	RNA-binding motif; other site
1171376006071	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1171376006072	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1171376006073	Walker A/P-loop; other site
1171376006074	ATP binding site [chemical binding]; other site
1171376006075	Q-loop/lid; other site
1171376006076	ABC transporter signature motif; other site
1171376006077	Walker B; other site
1171376006078	D-loop; other site
1171376006079	H-loop/switch region; other site
1171376006080	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1171376006081	FtsX-like permease family; Region: FtsX; pfam02687
1171376006082	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1171376006083	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1171376006084	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376006085	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
1171376006086	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1171376006087	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1171376006088	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1171376006089	putative active site [active]
1171376006090	putative metal-binding site [ion binding]; other site
1171376006091	Predicted membrane protein [Function unknown]; Region: COG2431
1171376006092	hybrid cluster protein; Provisional; Region: PRK05290
1171376006093	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1171376006094	ACS interaction site; other site
1171376006095	CODH interaction site; other site
1171376006096	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1171376006097	hybrid metal cluster; other site
1171376006098	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1171376006099	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1171376006100	FAD binding pocket [chemical binding]; other site
1171376006101	FAD binding motif [chemical binding]; other site
1171376006102	phosphate binding motif [ion binding]; other site
1171376006103	beta-alpha-beta structure motif; other site
1171376006104	NAD binding pocket [chemical binding]; other site
1171376006105	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1171376006106	catalytic loop [active]
1171376006107	iron binding site [ion binding]; other site
1171376006108	pyruvate dehydrogenase; Provisional; Region: PRK09124
1171376006109	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1171376006110	PYR/PP interface [polypeptide binding]; other site
1171376006111	dimer interface [polypeptide binding]; other site
1171376006112	tetramer interface [polypeptide binding]; other site
1171376006113	TPP binding site [chemical binding]; other site
1171376006114	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1171376006115	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1171376006116	TPP-binding site [chemical binding]; other site
1171376006117	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1171376006118	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1171376006119	tetramer interface [polypeptide binding]; other site
1171376006120	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376006121	catalytic residue [active]
1171376006122	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1171376006123	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1171376006124	putative NAD(P) binding site [chemical binding]; other site
1171376006125	putative active site [active]
1171376006126	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1171376006127	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1171376006128	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1171376006129	NAD(P) binding site [chemical binding]; other site
1171376006130	active site
1171376006131	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1171376006132	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1171376006133	amidase catalytic site [active]
1171376006134	Zn binding residues [ion binding]; other site
1171376006135	substrate binding site [chemical binding]; other site
1171376006136	hypothetical protein; Provisional; Region: PRK02877
1171376006137	putative lipoprotein; Provisional; Region: PRK10533
1171376006138	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1171376006139	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376006140	Walker A/P-loop; other site
1171376006141	ATP binding site [chemical binding]; other site
1171376006142	Q-loop/lid; other site
1171376006143	ABC transporter signature motif; other site
1171376006144	Walker B; other site
1171376006145	D-loop; other site
1171376006146	H-loop/switch region; other site
1171376006147	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1171376006148	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376006149	substrate binding pocket [chemical binding]; other site
1171376006150	membrane-bound complex binding site; other site
1171376006151	hinge residues; other site
1171376006152	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1171376006153	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376006154	dimer interface [polypeptide binding]; other site
1171376006155	conserved gate region; other site
1171376006156	putative PBP binding loops; other site
1171376006157	ABC-ATPase subunit interface; other site
1171376006158	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376006159	dimer interface [polypeptide binding]; other site
1171376006160	conserved gate region; other site
1171376006161	putative PBP binding loops; other site
1171376006162	ABC-ATPase subunit interface; other site
1171376006163	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1171376006164	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376006165	substrate binding pocket [chemical binding]; other site
1171376006166	membrane-bound complex binding site; other site
1171376006167	hinge residues; other site
1171376006168	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1171376006169	Sulfatase; Region: Sulfatase; cl17466
1171376006170	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1171376006171	active site
1171376006172	P-loop; other site
1171376006173	phosphorylation site [posttranslational modification]
1171376006174	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1171376006175	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1171376006176	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376006177	S-adenosylmethionine binding site [chemical binding]; other site
1171376006178	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1171376006179	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1171376006180	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376006181	dimer interface [polypeptide binding]; other site
1171376006182	conserved gate region; other site
1171376006183	putative PBP binding loops; other site
1171376006184	ABC-ATPase subunit interface; other site
1171376006185	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1171376006186	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376006187	dimer interface [polypeptide binding]; other site
1171376006188	conserved gate region; other site
1171376006189	putative PBP binding loops; other site
1171376006190	ABC-ATPase subunit interface; other site
1171376006191	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1171376006192	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376006193	Walker A/P-loop; other site
1171376006194	ATP binding site [chemical binding]; other site
1171376006195	Q-loop/lid; other site
1171376006196	ABC transporter signature motif; other site
1171376006197	Walker B; other site
1171376006198	D-loop; other site
1171376006199	H-loop/switch region; other site
1171376006200	TOBE domain; Region: TOBE_2; pfam08402
1171376006201	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1171376006202	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1171376006203	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1171376006204	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1171376006205	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1171376006206	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1171376006207	dimer interface [polypeptide binding]; other site
1171376006208	FMN binding site [chemical binding]; other site
1171376006209	NADPH bind site [chemical binding]; other site
1171376006210	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
1171376006211	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1171376006212	GSH binding site [chemical binding]; other site
1171376006213	catalytic residues [active]
1171376006214	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1171376006215	putative transporter; Provisional; Region: PRK04972
1171376006216	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1171376006217	TrkA-C domain; Region: TrkA_C; pfam02080
1171376006218	TrkA-C domain; Region: TrkA_C; pfam02080
1171376006219	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1171376006220	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
1171376006221	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376006222	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1171376006223	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376006224	putative substrate translocation pore; other site
1171376006225	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1171376006226	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1171376006227	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376006228	active site
1171376006229	motif I; other site
1171376006230	motif II; other site
1171376006231	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376006232	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1171376006233	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376006234	putative substrate translocation pore; other site
1171376006235	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1171376006236	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1171376006237	active site
1171376006238	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1171376006239	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1171376006240	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376006241	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1171376006242	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1171376006243	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1171376006244	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1171376006245	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1171376006246	putative C-terminal domain interface [polypeptide binding]; other site
1171376006247	putative GSH binding site (G-site) [chemical binding]; other site
1171376006248	putative dimer interface [polypeptide binding]; other site
1171376006249	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1171376006250	putative N-terminal domain interface [polypeptide binding]; other site
1171376006251	putative dimer interface [polypeptide binding]; other site
1171376006252	putative substrate binding pocket (H-site) [chemical binding]; other site
1171376006253	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1171376006254	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1171376006255	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1171376006256	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1171376006257	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1171376006258	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1171376006259	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376006260	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376006261	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421
1171376006262	putative dimerization interface [polypeptide binding]; other site
1171376006263	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
1171376006264	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1171376006265	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
1171376006266	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1171376006267	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1171376006268	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1171376006269	active site
1171376006270	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1171376006271	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1171376006272	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1171376006273	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1171376006274	Ligand binding site [chemical binding]; other site
1171376006275	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1171376006276	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1171376006277	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1171376006278	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1171376006279	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1171376006280	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376006281	FeS/SAM binding site; other site
1171376006282	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1171376006283	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1171376006284	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376006285	dimer interface [polypeptide binding]; other site
1171376006286	conserved gate region; other site
1171376006287	putative PBP binding loops; other site
1171376006288	ABC-ATPase subunit interface; other site
1171376006289	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1171376006290	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376006291	dimer interface [polypeptide binding]; other site
1171376006292	conserved gate region; other site
1171376006293	putative PBP binding loops; other site
1171376006294	ABC-ATPase subunit interface; other site
1171376006295	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1171376006296	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1171376006297	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1171376006298	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1171376006299	Walker A/P-loop; other site
1171376006300	ATP binding site [chemical binding]; other site
1171376006301	Q-loop/lid; other site
1171376006302	ABC transporter signature motif; other site
1171376006303	Walker B; other site
1171376006304	D-loop; other site
1171376006305	H-loop/switch region; other site
1171376006306	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1171376006307	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1171376006308	Walker A/P-loop; other site
1171376006309	ATP binding site [chemical binding]; other site
1171376006310	Q-loop/lid; other site
1171376006311	ABC transporter signature motif; other site
1171376006312	Walker B; other site
1171376006313	D-loop; other site
1171376006314	H-loop/switch region; other site
1171376006315	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1171376006316	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1171376006317	catalytic nucleophile [active]
1171376006318	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1171376006319	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1171376006320	dimer interface [polypeptide binding]; other site
1171376006321	putative functional site; other site
1171376006322	putative MPT binding site; other site
1171376006323	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1171376006324	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1171376006325	ATP binding site [chemical binding]; other site
1171376006326	substrate interface [chemical binding]; other site
1171376006327	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1171376006328	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376006329	FeS/SAM binding site; other site
1171376006330	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1171376006331	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1171376006332	dimer interface [polypeptide binding]; other site
1171376006333	active site
1171376006334	glycine loop; other site
1171376006335	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1171376006336	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376006337	active site
1171376006338	motif I; other site
1171376006339	motif II; other site
1171376006340	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376006341	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1171376006342	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1171376006343	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376006344	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
1171376006345	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1171376006346	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1171376006347	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376006348	Walker A/P-loop; other site
1171376006349	ATP binding site [chemical binding]; other site
1171376006350	ABC transporter signature motif; other site
1171376006351	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1171376006352	Walker B; other site
1171376006353	ABC transporter; Region: ABC_tran_2; pfam12848
1171376006354	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1171376006355	L,D-transpeptidase; Provisional; Region: PRK10260
1171376006356	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1171376006357	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1171376006358	transmembrane helices; other site
1171376006359	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1171376006360	manganese transport regulator MntR; Provisional; Region: PRK11050
1171376006361	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1171376006362	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1171376006363	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1171376006364	Sulfatase; Region: Sulfatase; pfam00884
1171376006365	outer membrane protein X; Provisional; Region: ompX; PRK09408
1171376006366	threonine and homoserine efflux system; Provisional; Region: PRK10532
1171376006367	EamA-like transporter family; Region: EamA; pfam00892
1171376006368	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1171376006369	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1171376006370	dimerization interface [polypeptide binding]; other site
1171376006371	DPS ferroxidase diiron center [ion binding]; other site
1171376006372	ion pore; other site
1171376006373	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1171376006374	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376006375	substrate binding pocket [chemical binding]; other site
1171376006376	membrane-bound complex binding site; other site
1171376006377	hinge residues; other site
1171376006378	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1171376006379	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376006380	dimer interface [polypeptide binding]; other site
1171376006381	conserved gate region; other site
1171376006382	putative PBP binding loops; other site
1171376006383	ABC-ATPase subunit interface; other site
1171376006384	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1171376006385	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1171376006386	Walker A/P-loop; other site
1171376006387	ATP binding site [chemical binding]; other site
1171376006388	Q-loop/lid; other site
1171376006389	ABC transporter signature motif; other site
1171376006390	Walker B; other site
1171376006391	D-loop; other site
1171376006392	H-loop/switch region; other site
1171376006393	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1171376006394	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1171376006395	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
1171376006396	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1171376006397	hypothetical protein; Provisional; Region: PRK11019
1171376006398	hypothetical protein; Provisional; Region: PRK10259
1171376006399	glycosyl transferase family protein; Provisional; Region: PRK08136
1171376006400	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1171376006401	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1171376006402	DEAD_2; Region: DEAD_2; pfam06733
1171376006403	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1171376006404	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1171376006405	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1171376006406	ATP binding site [chemical binding]; other site
1171376006407	Mg++ binding site [ion binding]; other site
1171376006408	motif III; other site
1171376006409	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376006410	nucleotide binding region [chemical binding]; other site
1171376006411	ATP-binding site [chemical binding]; other site
1171376006412	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1171376006413	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376006414	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1171376006415	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1171376006416	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1171376006417	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376006418	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1171376006419	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1171376006420	Walker A/P-loop; other site
1171376006421	ATP binding site [chemical binding]; other site
1171376006422	Q-loop/lid; other site
1171376006423	ABC transporter signature motif; other site
1171376006424	Walker B; other site
1171376006425	D-loop; other site
1171376006426	H-loop/switch region; other site
1171376006427	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1171376006428	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1171376006429	Walker A/P-loop; other site
1171376006430	ATP binding site [chemical binding]; other site
1171376006431	Q-loop/lid; other site
1171376006432	ABC transporter signature motif; other site
1171376006433	Walker B; other site
1171376006434	D-loop; other site
1171376006435	H-loop/switch region; other site
1171376006436	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1171376006437	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1171376006438	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1171376006439	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1171376006440	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1171376006441	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1171376006442	putative catalytic site [active]
1171376006443	putative metal binding site [ion binding]; other site
1171376006444	putative phosphate binding site [ion binding]; other site
1171376006445	cardiolipin synthase 2; Provisional; Region: PRK11263
1171376006446	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1171376006447	putative active site [active]
1171376006448	catalytic site [active]
1171376006449	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1171376006450	putative active site [active]
1171376006451	catalytic site [active]
1171376006452	Predicted integral membrane protein [Function unknown]; Region: COG0392
1171376006453	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1171376006454	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1171376006455	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1171376006456	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1171376006457	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1171376006458	MoaE homodimer interface [polypeptide binding]; other site
1171376006459	MoaD interaction [polypeptide binding]; other site
1171376006460	active site residues [active]
1171376006461	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1171376006462	MoaE interaction surface [polypeptide binding]; other site
1171376006463	MoeB interaction surface [polypeptide binding]; other site
1171376006464	thiocarboxylated glycine; other site
1171376006465	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1171376006466	trimer interface [polypeptide binding]; other site
1171376006467	dimer interface [polypeptide binding]; other site
1171376006468	putative active site [active]
1171376006469	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1171376006470	MPT binding site; other site
1171376006471	trimer interface [polypeptide binding]; other site
1171376006472	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1171376006473	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376006474	FeS/SAM binding site; other site
1171376006475	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1171376006476	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1171376006477	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1171376006478	putative substrate binding pocket [chemical binding]; other site
1171376006479	dimer interface [polypeptide binding]; other site
1171376006480	phosphate binding site [ion binding]; other site
1171376006481	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
1171376006482	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
1171376006483	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
1171376006484	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1171376006485	Leucine-rich repeats; other site
1171376006486	Substrate binding site [chemical binding]; other site
1171376006487	excinuclease ABC subunit B; Provisional; Region: PRK05298
1171376006488	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1171376006489	ATP binding site [chemical binding]; other site
1171376006490	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376006491	nucleotide binding region [chemical binding]; other site
1171376006492	ATP-binding site [chemical binding]; other site
1171376006493	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1171376006494	UvrB/uvrC motif; Region: UVR; pfam02151
1171376006495	AAA domain; Region: AAA_26; pfam13500
1171376006496	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1171376006497	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1171376006498	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376006499	S-adenosylmethionine binding site [chemical binding]; other site
1171376006500	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1171376006501	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1171376006502	substrate-cofactor binding pocket; other site
1171376006503	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376006504	catalytic residue [active]
1171376006505	biotin synthase; Provisional; Region: PRK15108
1171376006506	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376006507	FeS/SAM binding site; other site
1171376006508	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1171376006509	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1171376006510	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1171376006511	inhibitor-cofactor binding pocket; inhibition site
1171376006512	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376006513	catalytic residue [active]
1171376006514	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1171376006515	substrate binding site [chemical binding]; other site
1171376006516	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1171376006517	active sites [active]
1171376006518	tetramer interface [polypeptide binding]; other site
1171376006519	histidine utilization repressor; Provisional; Region: PRK14999
1171376006520	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376006521	DNA-binding site [nucleotide binding]; DNA binding site
1171376006522	UTRA domain; Region: UTRA; pfam07702
1171376006523	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
1171376006524	putative active site [active]
1171376006525	putative metal binding site [ion binding]; other site
1171376006526	imidazolonepropionase; Validated; Region: PRK09356
1171376006527	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1171376006528	active site
1171376006529	acyl-CoA thioesterase; Provisional; Region: PRK10531
1171376006530	putative pectinesterase; Region: PLN02432; cl01911
1171376006531	6-phosphogluconolactonase; Provisional; Region: PRK11028
1171376006532	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1171376006533	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376006534	active site
1171376006535	motif I; other site
1171376006536	motif II; other site
1171376006537	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376006538	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1171376006539	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376006540	Walker A/P-loop; other site
1171376006541	ATP binding site [chemical binding]; other site
1171376006542	Q-loop/lid; other site
1171376006543	ABC transporter signature motif; other site
1171376006544	Walker B; other site
1171376006545	D-loop; other site
1171376006546	H-loop/switch region; other site
1171376006547	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1171376006548	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1171376006549	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376006550	dimer interface [polypeptide binding]; other site
1171376006551	conserved gate region; other site
1171376006552	putative PBP binding loops; other site
1171376006553	ABC-ATPase subunit interface; other site
1171376006554	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1171376006555	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376006556	substrate binding pocket [chemical binding]; other site
1171376006557	membrane-bound complex binding site; other site
1171376006558	hinge residues; other site
1171376006559	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1171376006560	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1171376006561	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1171376006562	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1171376006563	TOBE domain; Region: TOBE; pfam03459
1171376006564	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1171376006565	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376006566	Walker A/P-loop; other site
1171376006567	ATP binding site [chemical binding]; other site
1171376006568	Q-loop/lid; other site
1171376006569	ABC transporter signature motif; other site
1171376006570	Walker B; other site
1171376006571	D-loop; other site
1171376006572	H-loop/switch region; other site
1171376006573	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376006574	Walker A/P-loop; other site
1171376006575	ATP binding site [chemical binding]; other site
1171376006576	Q-loop/lid; other site
1171376006577	ABC transporter signature motif; other site
1171376006578	Walker B; other site
1171376006579	D-loop; other site
1171376006580	H-loop/switch region; other site
1171376006581	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
1171376006582	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1171376006583	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1171376006584	NAD binding site [chemical binding]; other site
1171376006585	homodimer interface [polypeptide binding]; other site
1171376006586	active site
1171376006587	substrate binding site [chemical binding]; other site
1171376006588	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1171376006589	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1171376006590	dimer interface [polypeptide binding]; other site
1171376006591	active site
1171376006592	galactokinase; Provisional; Region: PRK05101
1171376006593	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1171376006594	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1171376006595	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1171376006596	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1171376006597	active site
1171376006598	catalytic residues [active]
1171376006599	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1171376006600	catalytic core [active]
1171376006601	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1171376006602	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1171376006603	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1171376006604	Walker A/P-loop; other site
1171376006605	ATP binding site [chemical binding]; other site
1171376006606	Q-loop/lid; other site
1171376006607	ABC transporter signature motif; other site
1171376006608	Walker B; other site
1171376006609	D-loop; other site
1171376006610	H-loop/switch region; other site
1171376006611	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1171376006612	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1171376006613	dimer interface [polypeptide binding]; other site
1171376006614	putative PBP binding regions; other site
1171376006615	ABC-ATPase subunit  interface; other site
1171376006616	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1171376006617	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1171376006618	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1171376006619	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1171376006620	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1171376006621	transmembrane helices; other site
1171376006622	cell density-dependent motility repressor; Provisional; Region: PRK10082
1171376006623	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376006624	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1171376006625	dimerization interface [polypeptide binding]; other site
1171376006626	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376006627	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376006628	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1171376006629	dimerization interface [polypeptide binding]; other site
1171376006630	fumarate hydratase; Provisional; Region: PRK06246
1171376006631	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain [Energy production and conversion]; Region: FumA; COG1838
1171376006632	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1171376006633	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1171376006634	YbgS-like protein; Region: YbgS; pfam13985
1171376006635	zinc transporter ZitB; Provisional; Region: PRK03557
1171376006636	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1171376006637	quinolinate synthetase; Provisional; Region: PRK09375
1171376006638	tol-pal system protein YbgF; Provisional; Region: PRK10803
1171376006639	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1171376006640	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1171376006641	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1171376006642	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1171376006643	ligand binding site [chemical binding]; other site
1171376006644	translocation protein TolB; Provisional; Region: tolB; PRK03629
1171376006645	TolB amino-terminal domain; Region: TolB_N; pfam04052
1171376006646	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1171376006647	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1171376006648	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1171376006649	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1171376006650	TolA C-terminal; Region: TolA; pfam06519
1171376006651	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1171376006652	colicin uptake protein TolR; Provisional; Region: PRK11024
1171376006653	colicin uptake protein TolQ; Provisional; Region: PRK10801
1171376006654	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1171376006655	active site
1171376006656	hypothetical protein; Provisional; Region: PRK10588
1171376006657	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
1171376006658	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1171376006659	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1171376006660	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1171376006661	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1171376006662	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1171376006663	CoA binding domain; Region: CoA_binding; smart00881
1171376006664	CoA-ligase; Region: Ligase_CoA; pfam00549
1171376006665	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1171376006666	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1171376006667	CoA-ligase; Region: Ligase_CoA; pfam00549
1171376006668	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1171376006669	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1171376006670	E3 interaction surface; other site
1171376006671	lipoyl attachment site [posttranslational modification]; other site
1171376006672	e3 binding domain; Region: E3_binding; pfam02817
1171376006673	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1171376006674	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1171376006675	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1171376006676	TPP-binding site [chemical binding]; other site
1171376006677	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1171376006678	dimer interface [polypeptide binding]; other site
1171376006679	PYR/PP interface [polypeptide binding]; other site
1171376006680	TPP binding site [chemical binding]; other site
1171376006681	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1171376006682	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1171376006683	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1171376006684	L-aspartate oxidase; Provisional; Region: PRK06175
1171376006685	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1171376006686	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1171376006687	SdhC subunit interface [polypeptide binding]; other site
1171376006688	proximal heme binding site [chemical binding]; other site
1171376006689	cardiolipin binding site; other site
1171376006690	Iron-sulfur protein interface; other site
1171376006691	proximal quinone binding site [chemical binding]; other site
1171376006692	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1171376006693	Iron-sulfur protein interface; other site
1171376006694	proximal quinone binding site [chemical binding]; other site
1171376006695	SdhD (CybS) interface [polypeptide binding]; other site
1171376006696	proximal heme binding site [chemical binding]; other site
1171376006697	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1171376006698	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1171376006699	dimer interface [polypeptide binding]; other site
1171376006700	active site
1171376006701	citrylCoA binding site [chemical binding]; other site
1171376006702	NADH binding [chemical binding]; other site
1171376006703	cationic pore residues; other site
1171376006704	oxalacetate/citrate binding site [chemical binding]; other site
1171376006705	coenzyme A binding site [chemical binding]; other site
1171376006706	catalytic triad [active]
1171376006707	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1171376006708	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1171376006709	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1171376006710	endonuclease VIII; Provisional; Region: PRK10445
1171376006711	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
1171376006712	DNA binding site [nucleotide binding]
1171376006713	catalytic residue [active]
1171376006714	putative catalytic residues [active]
1171376006715	H2TH interface [polypeptide binding]; other site
1171376006716	intercalation triad [nucleotide binding]; other site
1171376006717	substrate specificity determining residue; other site
1171376006718	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1171376006719	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1171376006720	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1171376006721	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
1171376006722	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1171376006723	active site
1171376006724	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1171376006725	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1171376006726	active site
1171376006727	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1171376006728	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1171376006729	Walker A/P-loop; other site
1171376006730	ATP binding site [chemical binding]; other site
1171376006731	Q-loop/lid; other site
1171376006732	ABC transporter signature motif; other site
1171376006733	Walker B; other site
1171376006734	D-loop; other site
1171376006735	H-loop/switch region; other site
1171376006736	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1171376006737	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1171376006738	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1171376006739	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1171376006740	putative ADP-binding pocket [chemical binding]; other site
1171376006741	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1171376006742	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1171376006743	active site
1171376006744	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
1171376006745	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1171376006746	UDP-galactopyranose mutase; Region: GLF; pfam03275
1171376006747	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1171376006748	active site
1171376006749	DNA binding site [nucleotide binding]
1171376006750	Int/Topo IB signature motif; other site
1171376006751	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
1171376006752	putative active site [active]
1171376006753	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1171376006754	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1171376006755	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1171376006756	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1171376006757	metal-binding protein; Provisional; Region: PRK10799
1171376006758	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1171376006759	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376006760	putative substrate translocation pore; other site
1171376006761	POT family; Region: PTR2; pfam00854
1171376006762	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1171376006763	DNA photolyase; Region: DNA_photolyase; pfam00875
1171376006764	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1171376006765	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1171376006766	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1171376006767	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1171376006768	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1171376006769	sensor protein KdpD; Provisional; Region: PRK10490
1171376006770	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1171376006771	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1171376006772	Ligand Binding Site [chemical binding]; other site
1171376006773	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1171376006774	GAF domain; Region: GAF_3; pfam13492
1171376006775	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376006776	dimer interface [polypeptide binding]; other site
1171376006777	phosphorylation site [posttranslational modification]
1171376006778	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376006779	ATP binding site [chemical binding]; other site
1171376006780	Mg2+ binding site [ion binding]; other site
1171376006781	G-X-G motif; other site
1171376006782	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1171376006783	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376006784	active site
1171376006785	phosphorylation site [posttranslational modification]
1171376006786	intermolecular recognition site; other site
1171376006787	dimerization interface [polypeptide binding]; other site
1171376006788	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376006789	DNA binding site [nucleotide binding]
1171376006790	ornithine decarboxylase; Provisional; Region: PRK13578
1171376006791	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1171376006792	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1171376006793	homodimer interface [polypeptide binding]; other site
1171376006794	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376006795	catalytic residue [active]
1171376006796	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1171376006797	putrescine transporter; Provisional; Region: potE; PRK10655
1171376006798	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
1171376006799	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
1171376006800	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1171376006801	active site
1171376006802	substrate binding site [chemical binding]; other site
1171376006803	metal binding site [ion binding]; metal-binding site
1171376006804	replication initiation regulator SeqA; Provisional; Region: PRK11187
1171376006805	acyl-CoA esterase; Provisional; Region: PRK10673
1171376006806	PGAP1-like protein; Region: PGAP1; pfam07819
1171376006807	LexA regulated protein; Provisional; Region: PRK11675
1171376006808	flavodoxin FldA; Validated; Region: PRK09267
1171376006809	ferric uptake regulator; Provisional; Region: fur; PRK09462
1171376006810	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1171376006811	metal binding site 2 [ion binding]; metal-binding site
1171376006812	putative DNA binding helix; other site
1171376006813	metal binding site 1 [ion binding]; metal-binding site
1171376006814	dimer interface [polypeptide binding]; other site
1171376006815	structural Zn2+ binding site [ion binding]; other site
1171376006816	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376006817	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376006818	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1171376006819	putative dimerization interface [polypeptide binding]; other site
1171376006820	tricarballylate dehydrogenase; Validated; Region: PRK08274
1171376006821	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1171376006822	tricarballylate utilization protein B; Provisional; Region: PRK15033
1171376006823	citrate-proton symporter; Provisional; Region: PRK15075
1171376006824	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376006825	putative substrate translocation pore; other site
1171376006826	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1171376006827	YbfN-like lipoprotein; Region: YbfN; pfam13982
1171376006828	outer membrane porin, OprD family; Region: OprD; pfam03573
1171376006829	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1171376006830	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1171376006831	active site
1171376006832	HIGH motif; other site
1171376006833	nucleotide binding site [chemical binding]; other site
1171376006834	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1171376006835	KMSKS motif; other site
1171376006836	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1171376006837	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1171376006838	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1171376006839	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1171376006840	active site turn [active]
1171376006841	phosphorylation site [posttranslational modification]
1171376006842	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1171376006843	HPr interaction site; other site
1171376006844	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1171376006845	active site
1171376006846	phosphorylation site [posttranslational modification]
1171376006847	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1171376006848	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1171376006849	active site
1171376006850	trimer interface [polypeptide binding]; other site
1171376006851	allosteric site; other site
1171376006852	active site lid [active]
1171376006853	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1171376006854	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1171376006855	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1171376006856	active site
1171376006857	dimer interface [polypeptide binding]; other site
1171376006858	MarR family; Region: MarR; pfam01047
1171376006859	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1171376006860	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1171376006861	nucleotide binding site [chemical binding]; other site
1171376006862	UMP phosphatase; Provisional; Region: PRK10444
1171376006863	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376006864	active site
1171376006865	motif I; other site
1171376006866	motif II; other site
1171376006867	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376006868	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1171376006869	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1171376006870	active site
1171376006871	dimer interface [polypeptide binding]; other site
1171376006872	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1171376006873	Ligand Binding Site [chemical binding]; other site
1171376006874	Molecular Tunnel; other site
1171376006875	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1171376006876	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1171376006877	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1171376006878	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1171376006879	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376006880	FeS/SAM binding site; other site
1171376006881	TRAM domain; Region: TRAM; pfam01938
1171376006882	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1171376006883	PhoH-like protein; Region: PhoH; pfam02562
1171376006884	metal-binding heat shock protein; Provisional; Region: PRK00016
1171376006885	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1171376006886	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1171376006887	Transporter associated domain; Region: CorC_HlyC; smart01091
1171376006888	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1171376006889	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1171376006890	putative active site [active]
1171376006891	catalytic triad [active]
1171376006892	putative dimer interface [polypeptide binding]; other site
1171376006893	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1171376006894	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376006895	substrate binding pocket [chemical binding]; other site
1171376006896	membrane-bound complex binding site; other site
1171376006897	hinge residues; other site
1171376006898	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1171376006899	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376006900	dimer interface [polypeptide binding]; other site
1171376006901	conserved gate region; other site
1171376006902	putative PBP binding loops; other site
1171376006903	ABC-ATPase subunit interface; other site
1171376006904	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1171376006905	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376006906	dimer interface [polypeptide binding]; other site
1171376006907	conserved gate region; other site
1171376006908	putative PBP binding loops; other site
1171376006909	ABC-ATPase subunit interface; other site
1171376006910	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1171376006911	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1171376006912	Walker A/P-loop; other site
1171376006913	ATP binding site [chemical binding]; other site
1171376006914	Q-loop/lid; other site
1171376006915	ABC transporter signature motif; other site
1171376006916	Walker B; other site
1171376006917	D-loop; other site
1171376006918	H-loop/switch region; other site
1171376006919	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1171376006920	active site
1171376006921	tetramer interface [polypeptide binding]; other site
1171376006922	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
1171376006923	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
1171376006924	nucleotide binding site [chemical binding]; other site
1171376006925	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1171376006926	SBD interface [polypeptide binding]; other site
1171376006927	DnaJ domain; Region: DnaJ; pfam00226
1171376006928	HSP70 interaction site [polypeptide binding]; other site
1171376006929	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1171376006930	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
1171376006931	HSP70 interaction site [polypeptide binding]; other site
1171376006932	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1171376006933	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1171376006934	Sel1-like repeats; Region: SEL1; smart00671
1171376006935	Sel1-like repeats; Region: SEL1; smart00671
1171376006936	Sel1-like repeats; Region: SEL1; smart00671
1171376006937	Sel1-like repeats; Region: SEL1; smart00671
1171376006938	Sel1-like repeats; Region: SEL1; smart00671
1171376006939	hypothetical protein; Provisional; Region: PRK11032
1171376006940	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1171376006941	Propionate catabolism activator; Region: PrpR_N; pfam06506
1171376006942	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1171376006943	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376006944	Walker A motif; other site
1171376006945	ATP binding site [chemical binding]; other site
1171376006946	Walker B motif; other site
1171376006947	arginine finger; other site
1171376006948	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
1171376006949	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1171376006950	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1171376006951	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1171376006952	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1171376006953	HIGH motif; other site
1171376006954	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1171376006955	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1171376006956	active site
1171376006957	KMSKS motif; other site
1171376006958	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1171376006959	tRNA binding surface [nucleotide binding]; other site
1171376006960	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1171376006961	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1171376006962	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1171376006963	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1171376006964	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1171376006965	active site
1171376006966	(T/H)XGH motif; other site
1171376006967	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
1171376006968	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376006969	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376006970	homodimer interface [polypeptide binding]; other site
1171376006971	catalytic residue [active]
1171376006972	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1171376006973	catalytic core [active]
1171376006974	ribosome-associated protein; Provisional; Region: PRK11538
1171376006975	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1171376006976	penicillin-binding protein 2; Provisional; Region: PRK10795
1171376006977	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1171376006978	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1171376006979	cell wall shape-determining protein; Provisional; Region: PRK10794
1171376006980	rare lipoprotein A; Provisional; Region: PRK10672
1171376006981	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1171376006982	Sporulation related domain; Region: SPOR; pfam05036
1171376006983	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1171376006984	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1171376006985	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1171376006986	hypothetical protein; Provisional; Region: PRK04998
1171376006987	lipoate-protein ligase B; Provisional; Region: PRK14342
1171376006988	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1171376006989	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376006990	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1171376006991	substrate binding pocket [chemical binding]; other site
1171376006992	dimerization interface [polypeptide binding]; other site
1171376006993	lipoyl synthase; Provisional; Region: PRK05481
1171376006994	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376006995	FeS/SAM binding site; other site
1171376006996	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1171376006997	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1171376006998	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1171376006999	putative active site [active]
1171376007000	catalytic triad [active]
1171376007001	putative dimer interface [polypeptide binding]; other site
1171376007002	chromosome condensation membrane protein; Provisional; Region: PRK14196
1171376007003	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1171376007004	DNA-binding site [nucleotide binding]; DNA binding site
1171376007005	RNA-binding motif; other site
1171376007006	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1171376007007	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1171376007008	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1171376007009	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
1171376007010	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376007011	active site
1171376007012	phosphorylation site [posttranslational modification]
1171376007013	intermolecular recognition site; other site
1171376007014	dimerization interface [polypeptide binding]; other site
1171376007015	Transcriptional regulator; Region: CitT; pfam12431
1171376007016	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
1171376007017	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1171376007018	putative active site [active]
1171376007019	heme pocket [chemical binding]; other site
1171376007020	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376007021	ATP binding site [chemical binding]; other site
1171376007022	Mg2+ binding site [ion binding]; other site
1171376007023	G-X-G motif; other site
1171376007024	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1171376007025	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1171376007026	putative active site [active]
1171376007027	(T/H)XGH motif; other site
1171376007028	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1171376007029	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1171376007030	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1171376007031	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1171376007032	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1171376007033	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
1171376007034	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1171376007035	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1171376007036	transmembrane helices; other site
1171376007037	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1171376007038	B1 nucleotide binding pocket [chemical binding]; other site
1171376007039	B2 nucleotide binding pocket [chemical binding]; other site
1171376007040	CAS motifs; other site
1171376007041	active site
1171376007042	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1171376007043	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1171376007044	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1171376007045	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1171376007046	NAD binding site [chemical binding]; other site
1171376007047	catalytic Zn binding site [ion binding]; other site
1171376007048	structural Zn binding site [ion binding]; other site
1171376007049	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1171376007050	Ligand Binding Site [chemical binding]; other site
1171376007051	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1171376007052	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1171376007053	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1171376007054	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1171376007055	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
1171376007056	putative [4Fe-4S] binding site [ion binding]; other site
1171376007057	putative molybdopterin cofactor binding site [chemical binding]; other site
1171376007058	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
1171376007059	molybdopterin cofactor binding site; other site
1171376007060	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1171376007061	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1171376007062	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1171376007063	catalytic residue [active]
1171376007064	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1171376007065	catalytic residues [active]
1171376007066	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1171376007067	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376007068	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1171376007069	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1171376007070	dimer interface [polypeptide binding]; other site
1171376007071	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1171376007072	catalytic triad [active]
1171376007073	peroxidatic and resolving cysteines [active]
1171376007074	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1171376007075	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1171376007076	dimerization domain [polypeptide binding]; other site
1171376007077	dimer interface [polypeptide binding]; other site
1171376007078	catalytic residues [active]
1171376007079	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1171376007080	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376007081	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376007082	dimerization interface [polypeptide binding]; other site
1171376007083	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1171376007084	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1171376007085	Active Sites [active]
1171376007086	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1171376007087	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1171376007088	ParB-like nuclease domain; Region: ParBc; pfam02195
1171376007089	methionine aminotransferase; Validated; Region: PRK09082
1171376007090	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376007091	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376007092	homodimer interface [polypeptide binding]; other site
1171376007093	catalytic residue [active]
1171376007094	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1171376007095	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1171376007096	putative active site [active]
1171376007097	metal binding site [ion binding]; metal-binding site
1171376007098	Uncharacterized small protein [Function unknown]; Region: COG2879
1171376007099	carbon starvation protein A; Provisional; Region: PRK15015
1171376007100	Carbon starvation protein CstA; Region: CstA; pfam02554
1171376007101	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1171376007102	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1171376007103	CoenzymeA binding site [chemical binding]; other site
1171376007104	subunit interaction site [polypeptide binding]; other site
1171376007105	PHB binding site; other site
1171376007106	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1171376007107	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1171376007108	putative NAD(P) binding site [chemical binding]; other site
1171376007109	active site
1171376007110	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1171376007111	hydrophobic substrate binding pocket; other site
1171376007112	Isochorismatase family; Region: Isochorismatase; pfam00857
1171376007113	active site
1171376007114	conserved cis-peptide bond; other site
1171376007115	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1171376007116	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
1171376007117	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1171376007118	acyl-activating enzyme (AAE) consensus motif; other site
1171376007119	active site
1171376007120	AMP binding site [chemical binding]; other site
1171376007121	substrate binding site [chemical binding]; other site
1171376007122	isochorismate synthase EntC; Provisional; Region: PRK15016
1171376007123	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1171376007124	ABC-type Fe2+-enterobactin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG4592
1171376007125	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1171376007126	siderophore binding site; other site
1171376007127	enterobactin exporter EntS; Provisional; Region: PRK10489
1171376007128	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376007129	putative substrate translocation pore; other site
1171376007130	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1171376007131	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1171376007132	ABC-ATPase subunit  interface; other site
1171376007133	dimer interface [polypeptide binding]; other site
1171376007134	putative PBP binding regions; other site
1171376007135	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1171376007136	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1171376007137	ABC-ATPase subunit  interface; other site
1171376007138	dimer interface [polypeptide binding]; other site
1171376007139	putative PBP binding regions; other site
1171376007140	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1171376007141	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1171376007142	Walker A/P-loop; other site
1171376007143	ATP binding site [chemical binding]; other site
1171376007144	Q-loop/lid; other site
1171376007145	ABC transporter signature motif; other site
1171376007146	Walker B; other site
1171376007147	D-loop; other site
1171376007148	H-loop/switch region; other site
1171376007149	LPS O-antigen length regulator; Provisional; Region: PRK10381
1171376007150	Chain length determinant protein; Region: Wzz; pfam02706
1171376007151	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1171376007152	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1171376007153	acyl-activating enzyme (AAE) consensus motif; other site
1171376007154	AMP binding site [chemical binding]; other site
1171376007155	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1171376007156	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
1171376007157	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1171376007158	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1171376007159	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1171376007160	outer membrane receptor FepA; Provisional; Region: PRK13524
1171376007161	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1171376007162	N-terminal plug; other site
1171376007163	ligand-binding site [chemical binding]; other site
1171376007164	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
1171376007165	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1171376007166	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
1171376007167	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
1171376007168	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1171376007169	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1171376007170	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376007171	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1171376007172	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376007173	hypothetical protein; Provisional; Region: PRK10250
1171376007174	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1171376007175	dimer interface [polypeptide binding]; other site
1171376007176	FMN binding site [chemical binding]; other site
1171376007177	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1171376007178	active pocket/dimerization site; other site
1171376007179	active site
1171376007180	phosphorylation site [posttranslational modification]
1171376007181	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1171376007182	active site
1171376007183	phosphorylation site [posttranslational modification]
1171376007184	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1171376007185	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1171376007186	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1171376007187	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1171376007188	dimer interface [polypeptide binding]; other site
1171376007189	active site
1171376007190	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1171376007191	dimer interface [polypeptide binding]; other site
1171376007192	active site
1171376007193	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1171376007194	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1171376007195	putative active site [active]
1171376007196	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1171376007197	dimer interface [polypeptide binding]; other site
1171376007198	active site
1171376007199	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1171376007200	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376007201	ATP binding site [chemical binding]; other site
1171376007202	Walker B motif; other site
1171376007203	arginine finger; other site
1171376007204	Transcriptional antiterminator [Transcription]; Region: COG3933
1171376007205	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1171376007206	active pocket/dimerization site; other site
1171376007207	active site
1171376007208	phosphorylation site [posttranslational modification]
1171376007209	PRD domain; Region: PRD; pfam00874
1171376007210	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1171376007211	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1171376007212	active site
1171376007213	oxyanion hole [active]
1171376007214	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1171376007215	catalytic triad [active]
1171376007216	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1171376007217	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1171376007218	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1171376007219	phenylalanine transporter; Provisional; Region: PRK10249
1171376007220	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
1171376007221	Predicted membrane protein [Function unknown]; Region: COG3059
1171376007222	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1171376007223	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
1171376007224	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376007225	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1171376007226	Cupin; Region: Cupin_6; pfam12852
1171376007227	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1171376007228	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376007229	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376007230	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
1171376007231	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376007232	ATP binding site [chemical binding]; other site
1171376007233	Mg2+ binding site [ion binding]; other site
1171376007234	G-X-G motif; other site
1171376007235	Predicted membrane protein [Function unknown]; Region: COG2246
1171376007236	GtrA-like protein; Region: GtrA; pfam04138
1171376007237	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1171376007238	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1171376007239	Ligand binding site; other site
1171376007240	Putative Catalytic site; other site
1171376007241	DXD motif; other site
1171376007242	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1171376007243	Transposase; Region: HTH_Tnp_1; pfam01527
1171376007244	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1171376007245	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
1171376007246	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376007247	DNA binding residues [nucleotide binding]
1171376007248	dimerization interface [polypeptide binding]; other site
1171376007249	transcriptional regulator FimZ; Provisional; Region: PRK09935
1171376007250	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376007251	active site
1171376007252	phosphorylation site [posttranslational modification]
1171376007253	intermolecular recognition site; other site
1171376007254	dimerization interface [polypeptide binding]; other site
1171376007255	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376007256	DNA binding residues [nucleotide binding]
1171376007257	dimerization interface [polypeptide binding]; other site
1171376007258	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
1171376007259	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
1171376007260	outer membrane usher protein FimD; Provisional; Region: PRK15198
1171376007261	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376007262	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376007263	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376007264	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1171376007265	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376007266	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376007267	fimbrial protein FimI; Provisional; Region: PRK15200
1171376007268	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
1171376007269	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1171376007270	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1171376007271	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1171376007272	homodimer interface [polypeptide binding]; other site
1171376007273	NADP binding site [chemical binding]; other site
1171376007274	substrate binding site [chemical binding]; other site
1171376007275	ribosome-associated protein; Provisional; Region: PRK11507
1171376007276	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1171376007277	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4727
1171376007278	Uncharacterized protein conserved in bacteria (DUF2145); Region: DUF2145; pfam09916
1171376007279	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1171376007280	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1171376007281	active site
1171376007282	HIGH motif; other site
1171376007283	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1171376007284	KMSKS motif; other site
1171376007285	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1171376007286	tRNA binding surface [nucleotide binding]; other site
1171376007287	anticodon binding site; other site
1171376007288	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1171376007289	substrate binding site [chemical binding]; other site
1171376007290	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1171376007291	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1171376007292	putative active site [active]
1171376007293	putative metal binding site [ion binding]; other site
1171376007294	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1171376007295	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1171376007296	ATP-grasp domain; Region: ATP-grasp; pfam02222
1171376007297	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1171376007298	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1171376007299	putative substrate binding site [chemical binding]; other site
1171376007300	nucleotide binding site [chemical binding]; other site
1171376007301	nucleotide binding site [chemical binding]; other site
1171376007302	homodimer interface [polypeptide binding]; other site
1171376007303	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1171376007304	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1171376007305	membrane protein FdrA; Validated; Region: PRK06091
1171376007306	CoA binding domain; Region: CoA_binding; pfam02629
1171376007307	CoA-ligase; Region: Ligase_CoA; pfam00549
1171376007308	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
1171376007309	allantoate amidohydrolase; Region: AllC; TIGR03176
1171376007310	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1171376007311	active site
1171376007312	metal binding site [ion binding]; metal-binding site
1171376007313	dimer interface [polypeptide binding]; other site
1171376007314	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
1171376007315	Mif2/CENP-C like; Region: Mif2; pfam11699
1171376007316	Cupin domain; Region: Cupin_2; pfam07883
1171376007317	glycerate kinase II; Provisional; Region: PRK09932
1171376007318	putative uracil/xanthine transporter; Provisional; Region: PRK11412
1171376007319	allantoinase; Provisional; Region: PRK08044
1171376007320	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
1171376007321	active site
1171376007322	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily, YbbW-like; solute-binding domain; Region: SLC-NCS1sbd_YbbW-like; cd11485
1171376007323	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1171376007324	Na binding site [ion binding]; other site
1171376007325	putative substrate binding site [chemical binding]; other site
1171376007326	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376007327	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1171376007328	putative substrate translocation pore; other site
1171376007329	tartronate semialdehyde reductase; Provisional; Region: PRK15059
1171376007330	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1171376007331	hydroxypyruvate isomerase; Provisional; Region: PRK09997
1171376007332	glyoxylate carboligase; Provisional; Region: PRK11269
1171376007333	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1171376007334	PYR/PP interface [polypeptide binding]; other site
1171376007335	dimer interface [polypeptide binding]; other site
1171376007336	TPP binding site [chemical binding]; other site
1171376007337	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1171376007338	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
1171376007339	TPP-binding site [chemical binding]; other site
1171376007340	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
1171376007341	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1171376007342	Bacterial transcriptional regulator; Region: IclR; pfam01614
1171376007343	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
1171376007344	ureidoglycolate hydrolase; Provisional; Region: PRK03606
1171376007345	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1171376007346	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376007347	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376007348	dimerization interface [polypeptide binding]; other site
1171376007349	Predicted ATPase [General function prediction only]; Region: COG2603
1171376007350	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1171376007351	active site residue [active]
1171376007352	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376007353	dimer interface [polypeptide binding]; other site
1171376007354	conserved gate region; other site
1171376007355	ABC-ATPase subunit interface; other site
1171376007356	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
1171376007357	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1171376007358	Walker A/P-loop; other site
1171376007359	ATP binding site [chemical binding]; other site
1171376007360	Q-loop/lid; other site
1171376007361	ABC transporter signature motif; other site
1171376007362	Walker B; other site
1171376007363	D-loop; other site
1171376007364	H-loop/switch region; other site
1171376007365	NIL domain; Region: NIL; pfam09383
1171376007366	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1171376007367	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1171376007368	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1171376007369	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1171376007370	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1171376007371	FtsX-like permease family; Region: FtsX; pfam02687
1171376007372	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1171376007373	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1171376007374	Walker A/P-loop; other site
1171376007375	ATP binding site [chemical binding]; other site
1171376007376	Q-loop/lid; other site
1171376007377	ABC transporter signature motif; other site
1171376007378	Walker B; other site
1171376007379	D-loop; other site
1171376007380	H-loop/switch region; other site
1171376007381	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1171376007382	active site
1171376007383	catalytic triad [active]
1171376007384	oxyanion hole [active]
1171376007385	switch loop; other site
1171376007386	oxidoreductase; Provisional; Region: PRK08017
1171376007387	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1171376007388	NADP binding site [chemical binding]; other site
1171376007389	active site
1171376007390	steroid binding site; other site
1171376007391	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1171376007392	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1171376007393	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1171376007394	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1171376007395	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1171376007396	Walker A/P-loop; other site
1171376007397	ATP binding site [chemical binding]; other site
1171376007398	Q-loop/lid; other site
1171376007399	ABC transporter signature motif; other site
1171376007400	Walker B; other site
1171376007401	D-loop; other site
1171376007402	H-loop/switch region; other site
1171376007403	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1171376007404	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1171376007405	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1171376007406	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1171376007407	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1171376007408	DNA binding residues [nucleotide binding]
1171376007409	dimer interface [polypeptide binding]; other site
1171376007410	copper binding site [ion binding]; other site
1171376007411	copper exporting ATPase; Provisional; Region: copA; PRK10671
1171376007412	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1171376007413	metal-binding site [ion binding]
1171376007414	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1171376007415	metal-binding site [ion binding]
1171376007416	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1171376007417	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376007418	motif II; other site
1171376007419	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1171376007420	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
1171376007421	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1171376007422	putative deacylase active site [active]
1171376007423	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1171376007424	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1171376007425	active site
1171376007426	metal binding site [ion binding]; metal-binding site
1171376007427	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1171376007428	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376007429	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1171376007430	putative substrate translocation pore; other site
1171376007431	putative cation:proton antiport protein; Provisional; Region: PRK10669
1171376007432	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1171376007433	TrkA-N domain; Region: TrkA_N; pfam02254
1171376007434	inosine/guanosine kinase; Provisional; Region: PRK15074
1171376007435	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376007436	acetyl esterase; Provisional; Region: PRK10162
1171376007437	ferrochelatase; Reviewed; Region: hemH; PRK00035
1171376007438	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1171376007439	C-terminal domain interface [polypeptide binding]; other site
1171376007440	active site
1171376007441	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1171376007442	active site
1171376007443	N-terminal domain interface [polypeptide binding]; other site
1171376007444	adenylate kinase; Reviewed; Region: adk; PRK00279
1171376007445	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1171376007446	AMP-binding site [chemical binding]; other site
1171376007447	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1171376007448	heat shock protein 90; Provisional; Region: PRK05218
1171376007449	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376007450	ATP binding site [chemical binding]; other site
1171376007451	Mg2+ binding site [ion binding]; other site
1171376007452	G-X-G motif; other site
1171376007453	recombination protein RecR; Reviewed; Region: recR; PRK00076
1171376007454	RecR protein; Region: RecR; pfam02132
1171376007455	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1171376007456	putative active site [active]
1171376007457	putative metal-binding site [ion binding]; other site
1171376007458	tetramer interface [polypeptide binding]; other site
1171376007459	hypothetical protein; Validated; Region: PRK00153
1171376007460	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1171376007461	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376007462	Walker A motif; other site
1171376007463	ATP binding site [chemical binding]; other site
1171376007464	Walker B motif; other site
1171376007465	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1171376007466	arginine finger; other site
1171376007467	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1171376007468	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1171376007469	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1171376007470	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1171376007471	active site
1171376007472	hypothetical protein; Provisional; Region: PRK10527
1171376007473	primosomal replication protein N''; Provisional; Region: PRK10093
1171376007474	hypothetical protein; Provisional; Region: PRK11038
1171376007475	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1171376007476	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1171376007477	hypothetical protein; Provisional; Region: PRK11281
1171376007478	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1171376007479	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
1171376007480	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1171376007481	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1171376007482	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376007483	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1171376007484	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1171376007485	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376007486	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1171376007487	Protein export membrane protein; Region: SecD_SecF; cl14618
1171376007488	Protein export membrane protein; Region: SecD_SecF; cl14618
1171376007489	Hha toxicity attenuator; Provisional; Region: PRK10667
1171376007490	gene expression modulator; Provisional; Region: PRK10945
1171376007491	maltose O-acetyltransferase; Provisional; Region: PRK10092
1171376007492	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1171376007493	active site
1171376007494	substrate binding site [chemical binding]; other site
1171376007495	trimer interface [polypeptide binding]; other site
1171376007496	CoA binding site [chemical binding]; other site
1171376007497	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1171376007498	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1171376007499	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1171376007500	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1171376007501	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1171376007502	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376007503	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1171376007504	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1171376007505	DNA binding site [nucleotide binding]
1171376007506	active site
1171376007507	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1171376007508	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1171376007509	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1171376007510	active site
1171376007511	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1171376007512	catalytic triad [active]
1171376007513	dimer interface [polypeptide binding]; other site
1171376007514	ammonium transporter; Provisional; Region: PRK10666
1171376007515	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1171376007516	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1171376007517	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1171376007518	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1171376007519	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376007520	Walker A/P-loop; other site
1171376007521	ATP binding site [chemical binding]; other site
1171376007522	Q-loop/lid; other site
1171376007523	ABC transporter signature motif; other site
1171376007524	Walker B; other site
1171376007525	D-loop; other site
1171376007526	H-loop/switch region; other site
1171376007527	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1171376007528	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1171376007529	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376007530	Walker A/P-loop; other site
1171376007531	ATP binding site [chemical binding]; other site
1171376007532	Q-loop/lid; other site
1171376007533	ABC transporter signature motif; other site
1171376007534	Walker B; other site
1171376007535	D-loop; other site
1171376007536	H-loop/switch region; other site
1171376007537	potential frameshift: common BLAST hit: gi|205351769|ref|YP_002225570.1| transcriptional regulator
1171376007538	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1171376007539	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1171376007540	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1171376007541	catalytic residue [active]
1171376007542	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1171376007543	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376007544	active site
1171376007545	motif I; other site
1171376007546	motif II; other site
1171376007547	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1171376007548	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1171376007549	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1171376007550	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1171376007551	Ligand Binding Site [chemical binding]; other site
1171376007552	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1171376007553	active site
1171376007554	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1171376007555	periplasmic folding chaperone; Provisional; Region: PRK10788
1171376007556	SurA N-terminal domain; Region: SurA_N_3; cl07813
1171376007557	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1171376007558	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1171376007559	IHF dimer interface [polypeptide binding]; other site
1171376007560	IHF - DNA interface [nucleotide binding]; other site
1171376007561	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1171376007562	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1171376007563	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1171376007564	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376007565	Walker A motif; other site
1171376007566	ATP binding site [chemical binding]; other site
1171376007567	Walker B motif; other site
1171376007568	arginine finger; other site
1171376007569	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1171376007570	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1171376007571	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1171376007572	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376007573	Walker A motif; other site
1171376007574	ATP binding site [chemical binding]; other site
1171376007575	Walker B motif; other site
1171376007576	Iron permease FTR1 family; Region: FTR1; cl00475
1171376007577	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1171376007578	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1171376007579	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1171376007580	oligomer interface [polypeptide binding]; other site
1171376007581	active site residues [active]
1171376007582	trigger factor; Provisional; Region: tig; PRK01490
1171376007583	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1171376007584	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1171376007585	transcriptional regulator BolA; Provisional; Region: PRK11628
1171376007586	hypothetical protein; Provisional; Region: PRK11627
1171376007587	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1171376007588	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1171376007589	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376007590	putative substrate translocation pore; other site
1171376007591	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1171376007592	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1171376007593	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1171376007594	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1171376007595	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1171376007596	D-pathway; other site
1171376007597	Putative ubiquinol binding site [chemical binding]; other site
1171376007598	Low-spin heme (heme b) binding site [chemical binding]; other site
1171376007599	Putative water exit pathway; other site
1171376007600	Binuclear center (heme o3/CuB) [ion binding]; other site
1171376007601	K-pathway; other site
1171376007602	Putative proton exit pathway; other site
1171376007603	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1171376007604	Subunit I/III interface [polypeptide binding]; other site
1171376007605	Subunit III/IV interface [polypeptide binding]; other site
1171376007606	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1171376007607	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1171376007608	UbiA prenyltransferase family; Region: UbiA; pfam01040
1171376007609	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1171376007610	Sel1-like repeats; Region: SEL1; smart00671
1171376007611	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1171376007612	Sel1-like repeats; Region: SEL1; smart00671
1171376007613	Sel1-like repeats; Region: SEL1; smart00671
1171376007614	Sel1-like repeats; Region: SEL1; smart00671
1171376007615	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1171376007616	Sel1 repeat; Region: Sel1; pfam08238
1171376007617	Sel1-like repeats; Region: SEL1; smart00671
1171376007618	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376007619	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1171376007620	putative substrate translocation pore; other site
1171376007621	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1171376007622	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1171376007623	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1171376007624	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1171376007625	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1171376007626	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1171376007627	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1171376007628	conserved cys residue [active]
1171376007629	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
1171376007630	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376007631	motif II; other site
1171376007632	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
1171376007633	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1171376007634	catalytic residue [active]
1171376007635	transcriptional regulator protein; Region: phnR; TIGR03337
1171376007636	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376007637	DNA-binding site [nucleotide binding]; DNA binding site
1171376007638	UTRA domain; Region: UTRA; pfam07702
1171376007639	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
1171376007640	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1171376007641	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
1171376007642	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376007643	Walker A/P-loop; other site
1171376007644	ATP binding site [chemical binding]; other site
1171376007645	Q-loop/lid; other site
1171376007646	ABC transporter signature motif; other site
1171376007647	Walker B; other site
1171376007648	D-loop; other site
1171376007649	H-loop/switch region; other site
1171376007650	TOBE domain; Region: TOBE_2; pfam08402
1171376007651	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
1171376007652	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376007653	dimer interface [polypeptide binding]; other site
1171376007654	conserved gate region; other site
1171376007655	putative PBP binding loops; other site
1171376007656	ABC-ATPase subunit interface; other site
1171376007657	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1171376007658	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376007659	dimer interface [polypeptide binding]; other site
1171376007660	conserved gate region; other site
1171376007661	ABC-ATPase subunit interface; other site
1171376007662	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1171376007663	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1171376007664	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1171376007665	Ligand Binding Site [chemical binding]; other site
1171376007666	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1171376007667	active site residue [active]
1171376007668	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1171376007669	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1171376007670	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1171376007671	substrate binding pocket [chemical binding]; other site
1171376007672	chain length determination region; other site
1171376007673	substrate-Mg2+ binding site; other site
1171376007674	catalytic residues [active]
1171376007675	aspartate-rich region 1; other site
1171376007676	active site lid residues [active]
1171376007677	aspartate-rich region 2; other site
1171376007678	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1171376007679	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1171376007680	TPP-binding site; other site
1171376007681	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1171376007682	PYR/PP interface [polypeptide binding]; other site
1171376007683	dimer interface [polypeptide binding]; other site
1171376007684	TPP binding site [chemical binding]; other site
1171376007685	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1171376007686	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1171376007687	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1171376007688	active site
1171376007689	catalytic tetrad [active]
1171376007690	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1171376007691	tetramer interfaces [polypeptide binding]; other site
1171376007692	binuclear metal-binding site [ion binding]; other site
1171376007693	thiamine monophosphate kinase; Provisional; Region: PRK05731
1171376007694	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1171376007695	ATP binding site [chemical binding]; other site
1171376007696	dimerization interface [polypeptide binding]; other site
1171376007697	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1171376007698	putative RNA binding site [nucleotide binding]; other site
1171376007699	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1171376007700	homopentamer interface [polypeptide binding]; other site
1171376007701	active site
1171376007702	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1171376007703	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1171376007704	catalytic motif [active]
1171376007705	Zn binding site [ion binding]; other site
1171376007706	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1171376007707	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1171376007708	ATP cone domain; Region: ATP-cone; pfam03477
1171376007709	hypothetical protein; Provisional; Region: PRK11530
1171376007710	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1171376007711	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1171376007712	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1171376007713	active site
1171376007714	Predicted transcriptional regulator [Transcription]; Region: COG2378
1171376007715	HTH domain; Region: HTH_11; pfam08279
1171376007716	WYL domain; Region: WYL; pfam13280
1171376007717	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
1171376007718	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1171376007719	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1171376007720	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1171376007721	Protein export membrane protein; Region: SecD_SecF; pfam02355
1171376007722	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1171376007723	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1171376007724	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1171376007725	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1171376007726	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1171376007727	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1171376007728	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1171376007729	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1171376007730	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1171376007731	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1171376007732	peroxidase; Provisional; Region: PRK15000
1171376007733	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1171376007734	dimer interface [polypeptide binding]; other site
1171376007735	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1171376007736	catalytic triad [active]
1171376007737	peroxidatic and resolving cysteines [active]
1171376007738	maltodextrin glucosidase; Provisional; Region: PRK10785
1171376007739	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1171376007740	homodimer interface [polypeptide binding]; other site
1171376007741	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1171376007742	active site
1171376007743	homodimer interface [polypeptide binding]; other site
1171376007744	catalytic site [active]
1171376007745	putative proline-specific permease; Provisional; Region: proY; PRK10580
1171376007746	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1171376007747	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1171376007748	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1171376007749	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1171376007750	putative active site [active]
1171376007751	heme pocket [chemical binding]; other site
1171376007752	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376007753	dimer interface [polypeptide binding]; other site
1171376007754	phosphorylation site [posttranslational modification]
1171376007755	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376007756	ATP binding site [chemical binding]; other site
1171376007757	Mg2+ binding site [ion binding]; other site
1171376007758	G-X-G motif; other site
1171376007759	transcriptional regulator PhoB; Provisional; Region: PRK10161
1171376007760	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376007761	active site
1171376007762	phosphorylation site [posttranslational modification]
1171376007763	intermolecular recognition site; other site
1171376007764	dimerization interface [polypeptide binding]; other site
1171376007765	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376007766	DNA binding site [nucleotide binding]
1171376007767	exonuclease subunit SbcD; Provisional; Region: PRK10966
1171376007768	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1171376007769	active site
1171376007770	metal binding site [ion binding]; metal-binding site
1171376007771	DNA binding site [nucleotide binding]
1171376007772	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1171376007773	exonuclease subunit SbcC; Provisional; Region: PRK10246
1171376007774	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376007775	Walker A/P-loop; other site
1171376007776	ATP binding site [chemical binding]; other site
1171376007777	Q-loop/lid; other site
1171376007778	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376007779	ABC transporter signature motif; other site
1171376007780	Walker B; other site
1171376007781	D-loop; other site
1171376007782	H-loop/switch region; other site
1171376007783	MFS transport protein AraJ; Provisional; Region: PRK10091
1171376007784	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376007785	putative substrate translocation pore; other site
1171376007786	fructokinase; Reviewed; Region: PRK09557
1171376007787	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1171376007788	nucleotide binding site [chemical binding]; other site
1171376007789	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
1171376007790	hypothetical protein; Provisional; Region: PRK10579
1171376007791	hypothetical protein; Provisional; Region: PRK10481
1171376007792	hypothetical protein; Provisional; Region: PRK10380
1171376007793	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1171376007794	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1171376007795	ADP binding site [chemical binding]; other site
1171376007796	magnesium binding site [ion binding]; other site
1171376007797	putative shikimate binding site; other site
1171376007798	hypothetical protein; Validated; Region: PRK00124
1171376007799	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1171376007800	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1171376007801	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
1171376007802	MASE2 domain; Region: MASE2; pfam05230
1171376007803	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376007804	metal binding site [ion binding]; metal-binding site
1171376007805	active site
1171376007806	I-site; other site
1171376007807	hypothetical protein; Provisional; Region: PRK11505
1171376007808	psiF repeat; Region: PsiF_repeat; pfam07769
1171376007809	psiF repeat; Region: PsiF_repeat; pfam07769
1171376007810	anti-RssB factor; Provisional; Region: PRK10244
1171376007811	drug efflux system protein MdtG; Provisional; Region: PRK09874
1171376007812	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376007813	putative substrate translocation pore; other site
1171376007814	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
1171376007815	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
1171376007816	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1171376007817	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1171376007818	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1171376007819	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
1171376007820	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
1171376007821	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1171376007822	microcin B17 transporter; Reviewed; Region: PRK11098
1171376007823	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1171376007824	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1171376007825	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1171376007826	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1171376007827	ligand binding site [chemical binding]; other site
1171376007828	flexible hinge region; other site
1171376007829	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
1171376007830	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1171376007831	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1171376007832	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1171376007833	dimer interface [polypeptide binding]; other site
1171376007834	active site
1171376007835	Schiff base residues; other site
1171376007836	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
1171376007837	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1171376007838	acyl-activating enzyme (AAE) consensus motif; other site
1171376007839	AMP binding site [chemical binding]; other site
1171376007840	active site
1171376007841	CoA binding site [chemical binding]; other site
1171376007842	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1171376007843	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1171376007844	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1171376007845	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
1171376007846	dimer interface [polypeptide binding]; other site
1171376007847	active site
1171376007848	citrylCoA binding site [chemical binding]; other site
1171376007849	oxalacetate/citrate binding site [chemical binding]; other site
1171376007850	coenzyme A binding site [chemical binding]; other site
1171376007851	catalytic triad [active]
1171376007852	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1171376007853	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1171376007854	tetramer interface [polypeptide binding]; other site
1171376007855	active site
1171376007856	Mg2+/Mn2+ binding site [ion binding]; other site
1171376007857	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1171376007858	Propionate catabolism activator; Region: PrpR_N; pfam06506
1171376007859	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376007860	Walker A motif; other site
1171376007861	ATP binding site [chemical binding]; other site
1171376007862	Walker B motif; other site
1171376007863	arginine finger; other site
1171376007864	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1171376007865	hypothetical protein; Provisional; Region: PRK09929
1171376007866	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
1171376007867	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1171376007868	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1171376007869	N-terminal plug; other site
1171376007870	ligand-binding site [chemical binding]; other site
1171376007871	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1171376007872	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1171376007873	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1171376007874	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1171376007875	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1171376007876	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
1171376007877	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1171376007878	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1171376007879	VRR-NUC domain; Region: VRR_NUC; pfam08774
1171376007880	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1171376007881	DNA methylase; Region: N6_N4_Mtase; cl17433
1171376007882	DNA methylase; Region: N6_N4_Mtase; pfam01555
1171376007883	putative sialic acid transporter; Region: 2A0112; TIGR00891
1171376007884	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376007885	putative substrate translocation pore; other site
1171376007886	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1171376007887	metal-binding site [ion binding]
1171376007888	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
1171376007889	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1171376007890	DNA binding residues [nucleotide binding]
1171376007891	dimer interface [polypeptide binding]; other site
1171376007892	copper binding site [ion binding]; other site
1171376007893	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1171376007894	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1171376007895	metal-binding site [ion binding]
1171376007896	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1171376007897	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376007898	motif II; other site
1171376007899	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1171376007900	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1171376007901	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376007902	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1171376007903	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1171376007904	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1171376007905	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1171376007906	DNA binding residues [nucleotide binding]
1171376007907	dimerization interface [polypeptide binding]; other site
1171376007908	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1171376007909	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1171376007910	DNA binding site [nucleotide binding]
1171376007911	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1171376007912	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376007913	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1171376007914	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1171376007915	fimbrial chaperone protein StbB; Provisional; Region: PRK15249
1171376007916	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376007917	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376007918	fimbrial outer membrane usher protein StbC; Provisional; Region: PRK15248
1171376007919	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376007920	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376007921	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376007922	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
1171376007923	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
1171376007924	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376007925	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376007926	YjzC-like protein; Region: YjzC; pfam14168
1171376007927	transcriptional activator TtdR; Provisional; Region: PRK09801
1171376007928	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376007929	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1171376007930	putative effector binding pocket; other site
1171376007931	putative dimerization interface [polypeptide binding]; other site
1171376007932	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1171376007933	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1171376007934	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1171376007935	3-isopropylmalate dehydratase small subunit [Amino acid transport and metabolism]; Region: LeuD; COG0066
1171376007936	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1171376007937	hypothetical protein; Provisional; Region: PRK14812
1171376007938	substrate binding site [chemical binding]; other site
1171376007939	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1171376007940	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1171376007941	substrate binding site [chemical binding]; other site
1171376007942	ligand binding site [chemical binding]; other site
1171376007943	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1171376007944	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376007945	putative substrate translocation pore; other site
1171376007946	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
1171376007947	potential frameshift: common BLAST hit: gi|197247887|ref|YP_002145307.1| glycerol dehydratase reactivation factor large subunit
1171376007948	HTH-like domain; Region: HTH_21; pfam13276
1171376007949	Integrase core domain; Region: rve; pfam00665
1171376007950	Integrase core domain; Region: rve_2; pfam13333
1171376007951	Predicted membrane protein [Function unknown]; Region: COG2246
1171376007952	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1171376007953	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1171376007954	Ligand binding site; other site
1171376007955	Putative Catalytic site; other site
1171376007956	DXD motif; other site
1171376007957	O-antigen conversion protein C; Region: PHA01514
1171376007958	Head binding; Region: Head_binding; pfam09008
1171376007959	Salmonella phage P22 tail-spike; Region: PhageP22-tail; pfam09251
1171376007960	Mnt; Region: mnt; PHA01513
1171376007961	Arc-like DNA binding domain; Region: Arc; pfam03869
1171376007962	Regulatory protein Mnt; Region: Repressor_Mnt; pfam11423
1171376007963	Protein of unknown function (DUF2824); Region: DUF2824; pfam11039
1171376007964	Phage stabilisation protein; Region: Phage_stabilise; pfam11134
1171376007965	P22 tail accessory factor; Region: P22_Tail-4; pfam11650
1171376007966	coat protein; Region: PHA01511
1171376007967	P22 coat protein - gene protein 5; Region: P22_CoatProtein; pfam11651
1171376007968	Bacteriophage, scaffolding protein; Region: Phage-scaffold; pfam09306
1171376007969	Terminase-like family; Region: Terminase_6; pfam03237
1171376007970	Bacteriophage terminase large (ATPase) subunit and inactivated derivatives [General function prediction only]; Region: COG5565
1171376007971	hypothetical protein; Region: PHA00527
1171376007972	hypothetical protein; Region: PHA00780
1171376007973	KilA-N domain; Region: KilA-N; pfam04383
1171376007974	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1171376007975	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1171376007976	catalytic residues [active]
1171376007977	Antitermination protein; Region: Antiterm; pfam03589
1171376007978	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1171376007979	Antitermination protein; Region: Antiterm; pfam03589
1171376007980	Phage NinH protein; Region: Phage_NinH; pfam06322
1171376007981	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1171376007982	NinF protein; Region: NinF; pfam05810
1171376007983	Protein of unknown function (DUF2591); Region: DUF2591; cl11584
1171376007984	NINE Protein; Region: NinE; pfam05322
1171376007985	NinB protein; Region: NinB; pfam05772
1171376007986	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1171376007987	DnaB-like helicase C terminal domain; Region: DnaB_C; pfam03796
1171376007988	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1171376007989	Walker A motif; other site
1171376007990	ATP binding site [chemical binding]; other site
1171376007991	Walker B motif; other site
1171376007992	DNA binding loops [nucleotide binding]
1171376007993	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1171376007994	Bacteriophage CII protein; Region: Phage_CII; pfam05269
1171376007995	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
1171376007996	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376007997	non-specific DNA binding site [nucleotide binding]; other site
1171376007998	Predicted transcriptional regulator [Transcription]; Region: COG2932
1171376007999	salt bridge; other site
1171376008000	sequence-specific DNA binding site [nucleotide binding]; other site
1171376008001	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1171376008002	Catalytic site [active]
1171376008003	P63C domain; Region: P63C; pfam10546
1171376008004	Superinfection exclusion protein B; Region: SieB; pfam14163
1171376008005	Antirestriction protein Ral; Region: Ral; pfam11058
1171376008006	hypothetical protein; Region: PHA01516
1171376008007	Lambda Phage CIII; Region: Lambda_CIII; pfam02061
1171376008008	Rad52/22 family double-strand break repair protein; Region: Rad52_Rad22; cl01936
1171376008009	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1171376008010	Protein of unknown function (DUF2856); Region: DUF2856; pfam11043
1171376008011	Protein of unknown function (DUF2737); Region: DUF2737; pfam10930
1171376008012	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1171376008013	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1171376008014	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
1171376008015	Helix-turn-helix domain; Region: HTH_17; pfam12728
1171376008016	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1171376008017	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
1171376008018	Int/Topo IB signature motif; other site
1171376008019	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1171376008020	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1171376008021	putative catalytic cysteine [active]
1171376008022	gamma-glutamyl kinase; Provisional; Region: PRK05429
1171376008023	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1171376008024	nucleotide binding site [chemical binding]; other site
1171376008025	homotetrameric interface [polypeptide binding]; other site
1171376008026	putative phosphate binding site [ion binding]; other site
1171376008027	putative allosteric binding site; other site
1171376008028	PUA domain; Region: PUA; pfam01472
1171376008029	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1171376008030	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1171376008031	trimer interface [polypeptide binding]; other site
1171376008032	eyelet of channel; other site
1171376008033	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1171376008034	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1171376008035	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1171376008036	active site
1171376008037	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1171376008038	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1171376008039	metal binding site [ion binding]; metal-binding site
1171376008040	dimer interface [polypeptide binding]; other site
1171376008041	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1171376008042	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1171376008043	Uncharacterized protein family UPF0027; Region: UPF0027; cl17455
1171376008044	hypothetical protein; Reviewed; Region: PRK09588
1171376008045	Uncharacterized protein family UPF0027; Region: UPF0027; cl17455
1171376008046	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1171376008047	active site
1171376008048	DNA polymerase IV; Validated; Region: PRK02406
1171376008049	DNA binding site [nucleotide binding]
1171376008050	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1171376008051	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1171376008052	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1171376008053	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1171376008054	putative active site [active]
1171376008055	putative dimer interface [polypeptide binding]; other site
1171376008056	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1171376008057	dimer interface [polypeptide binding]; other site
1171376008058	active site
1171376008059	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1171376008060	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1171376008061	active site
1171376008062	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1171376008063	C-N hydrolase family amidase; Provisional; Region: PRK10438
1171376008064	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1171376008065	putative active site [active]
1171376008066	catalytic triad [active]
1171376008067	dimer interface [polypeptide binding]; other site
1171376008068	multimer interface [polypeptide binding]; other site
1171376008069	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1171376008070	dimer interface [polypeptide binding]; other site
1171376008071	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1171376008072	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376008073	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376008074	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376008075	dimerization interface [polypeptide binding]; other site
1171376008076	PerC transcriptional activator; Region: PerC; pfam06069
1171376008077	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1171376008078	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
1171376008079	putative active site [active]
1171376008080	putative metal binding site [ion binding]; other site
1171376008081	putative pilin structural protein SafD; Provisional; Region: PRK15222
1171376008082	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
1171376008083	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376008084	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376008085	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376008086	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
1171376008087	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376008088	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376008089	Saf-pilin pilus formation protein SafA; Provisional; Region: PRK15221
1171376008090	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1171376008091	Integrase core domain; Region: rve_3; pfam13683
1171376008092	Transposase; Region: HTH_Tnp_1; cl17663
1171376008093	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
1171376008094	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
1171376008095	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1171376008096	RHS protein; Region: RHS; pfam03527
1171376008097	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1171376008098	PAAR motif; Region: PAAR_motif; pfam05488
1171376008099	RHS Repeat; Region: RHS_repeat; pfam05593
1171376008100	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1171376008101	RHS Repeat; Region: RHS_repeat; pfam05593
1171376008102	RHS Repeat; Region: RHS_repeat; pfam05593
1171376008103	RHS protein; Region: RHS; pfam03527
1171376008104	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1171376008105	Uncharacterized conserved protein [Function unknown]; Region: COG5435
1171376008106	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501
1171376008107	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1171376008108	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1171376008109	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4893
1171376008110	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; cl01611
1171376008111	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1171376008112	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1171376008113	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1171376008114	hypothetical protein; Provisional; Region: PRK08126
1171376008115	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
1171376008116	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1171376008117	ligand binding site [chemical binding]; other site
1171376008118	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
1171376008119	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1171376008120	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
1171376008121	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1171376008122	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
1171376008123	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1171376008124	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1171376008125	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1171376008126	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
1171376008127	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1171376008128	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376008129	Walker A motif; other site
1171376008130	ATP binding site [chemical binding]; other site
1171376008131	Walker B motif; other site
1171376008132	arginine finger; other site
1171376008133	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376008134	Walker A motif; other site
1171376008135	ATP binding site [chemical binding]; other site
1171376008136	Walker B motif; other site
1171376008137	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1171376008138	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
1171376008139	ImpE protein; Region: ImpE; pfam07024
1171376008140	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
1171376008141	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1171376008142	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1171376008143	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
1171376008144	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1171376008145	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1171376008146	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1171376008147	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1171376008148	active site
1171376008149	catalytic site [active]
1171376008150	substrate binding site [chemical binding]; other site
1171376008151	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1171376008152	RNA/DNA hybrid binding site [nucleotide binding]; other site
1171376008153	active site
1171376008154	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376008155	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1171376008156	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
1171376008157	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1171376008158	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1171376008159	catalytic residue [active]
1171376008160	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1171376008161	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1171376008162	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1171376008163	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376008164	S-adenosylmethionine binding site [chemical binding]; other site
1171376008165	hypothetical protein; Provisional; Region: PRK05421
1171376008166	putative catalytic site [active]
1171376008167	putative metal binding site [ion binding]; other site
1171376008168	putative phosphate binding site [ion binding]; other site
1171376008169	putative catalytic site [active]
1171376008170	putative phosphate binding site [ion binding]; other site
1171376008171	putative metal binding site [ion binding]; other site
1171376008172	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1171376008173	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376008174	putative substrate translocation pore; other site
1171376008175	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376008176	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376008177	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
1171376008178	putative effector binding pocket; other site
1171376008179	dimerization interface [polypeptide binding]; other site
1171376008180	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1171376008181	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1171376008182	active site
1171376008183	catalytic tetrad [active]
1171376008184	protein disaggregation chaperone; Provisional; Region: PRK10865
1171376008185	Clp amino terminal domain; Region: Clp_N; pfam02861
1171376008186	Clp amino terminal domain; Region: Clp_N; pfam02861
1171376008187	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376008188	Walker A motif; other site
1171376008189	ATP binding site [chemical binding]; other site
1171376008190	Walker B motif; other site
1171376008191	arginine finger; other site
1171376008192	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376008193	Walker A motif; other site
1171376008194	ATP binding site [chemical binding]; other site
1171376008195	Walker B motif; other site
1171376008196	arginine finger; other site
1171376008197	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1171376008198	hypothetical protein; Provisional; Region: PRK10723
1171376008199	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1171376008200	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1171376008201	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1171376008202	RNA binding surface [nucleotide binding]; other site
1171376008203	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1171376008204	active site
1171376008205	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1171376008206	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1171376008207	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1171376008208	30S subunit binding site; other site
1171376008209	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1171376008210	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1171376008211	Prephenate dehydratase; Region: PDT; pfam00800
1171376008212	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1171376008213	putative L-Phe binding site [chemical binding]; other site
1171376008214	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1171376008215	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1171376008216	Chorismate mutase type II; Region: CM_2; cl00693
1171376008217	prephenate dehydrogenase; Validated; Region: PRK08507
1171376008218	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1171376008219	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1171376008220	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1171376008221	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1171376008222	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376008223	metal binding site [ion binding]; metal-binding site
1171376008224	active site
1171376008225	I-site; other site
1171376008226	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1171376008227	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1171376008228	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1171376008229	RimM N-terminal domain; Region: RimM; pfam01782
1171376008230	PRC-barrel domain; Region: PRC; pfam05239
1171376008231	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1171376008232	signal recognition particle protein; Provisional; Region: PRK10867
1171376008233	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1171376008234	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1171376008235	P loop; other site
1171376008236	GTP binding site [chemical binding]; other site
1171376008237	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1171376008238	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1171376008239	hypothetical protein; Provisional; Region: PRK11573
1171376008240	Domain of unknown function DUF21; Region: DUF21; pfam01595
1171376008241	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1171376008242	Transporter associated domain; Region: CorC_HlyC; smart01091
1171376008243	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1171376008244	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1171376008245	dimer interface [polypeptide binding]; other site
1171376008246	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1171376008247	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1171376008248	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1171376008249	recombination and repair protein; Provisional; Region: PRK10869
1171376008250	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1171376008251	Walker A/P-loop; other site
1171376008252	ATP binding site [chemical binding]; other site
1171376008253	Q-loop/lid; other site
1171376008254	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1171376008255	ABC transporter signature motif; other site
1171376008256	Walker B; other site
1171376008257	D-loop; other site
1171376008258	H-loop/switch region; other site
1171376008259	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1171376008260	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1171376008261	hypothetical protein; Validated; Region: PRK01777
1171376008262	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1171376008263	putative coenzyme Q binding site [chemical binding]; other site
1171376008264	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1171376008265	SmpB-tmRNA interface; other site
1171376008266	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008267	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008268	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008269	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008270	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008271	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008272	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008273	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008274	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008275	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008276	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008277	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1171376008278	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008279	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008280	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1171376008281	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008282	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376008283	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
1171376008284	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1171376008285	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1171376008286	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1171376008287	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376008288	Walker A/P-loop; other site
1171376008289	ATP binding site [chemical binding]; other site
1171376008290	Q-loop/lid; other site
1171376008291	ABC transporter signature motif; other site
1171376008292	Walker B; other site
1171376008293	D-loop; other site
1171376008294	H-loop/switch region; other site
1171376008295	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1171376008296	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376008297	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1171376008298	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1171376008299	tail protein; Provisional; Region: D; PHA02561
1171376008300	Phage protein U [General function prediction only]; Region: COG3499
1171376008301	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1171376008302	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1171376008303	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1171376008304	major tail tube protein; Provisional; Region: FII; PHA02600
1171376008305	major tail sheath protein; Provisional; Region: FI; PHA02560
1171376008306	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1171376008307	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1171376008308	catalytic residues [active]
1171376008309	catalytic nucleophile [active]
1171376008310	Presynaptic Site I dimer interface [polypeptide binding]; other site
1171376008311	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1171376008312	Synaptic Flat tetramer interface [polypeptide binding]; other site
1171376008313	Synaptic Site I dimer interface [polypeptide binding]; other site
1171376008314	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1171376008315	DNA-binding interface [nucleotide binding]; DNA binding site
1171376008316	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1171376008317	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1171376008318	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1171376008319	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1171376008320	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1171376008321	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1171376008322	baseplate assembly protein; Provisional; Region: J; PHA02568
1171376008323	baseplate wedge subunit; Provisional; Region: W; PHA02516
1171376008324	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1171376008325	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1171376008326	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1171376008327	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1171376008328	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1171376008329	potential frameshift: common BLAST hit: gi|383497395|ref|YP_005398084.1| bacteriophage protein
1171376008330	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1171376008331	catalytic residues [active]
1171376008332	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
1171376008333	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1171376008334	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1171376008335	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1171376008336	capsid protein; Provisional; Region: N; PHA02538
1171376008337	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
1171376008338	terminase ATPase subunit; Provisional; Region: P; PHA02535
1171376008339	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1171376008340	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
1171376008341	portal vertex protein; Provisional; Region: Q; PHA02536
1171376008342	Phage portal protein; Region: Phage_portal; pfam04860
1171376008343	AIPR protein; Region: AIPR; pfam10592
1171376008344	DinI-like family; Region: DinI; pfam06183
1171376008345	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1171376008346	DNA adenine methylase (dam); Region: dam; TIGR00571
1171376008347	DksA-like zinc finger domain containing protein; Region: PHA00080
1171376008348	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1171376008349	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
1171376008350	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
1171376008351	Predicted transcriptional regulator [Transcription]; Region: COG2932
1171376008352	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
1171376008353	integrase; Provisional; Region: int; PHA02601
1171376008354	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1171376008355	dimer interface [polypeptide binding]; other site
1171376008356	active site
1171376008357	catalytic residues [active]
1171376008358	Int/Topo IB signature motif; other site
1171376008359	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1171376008360	active site
1171376008361	Int/Topo IB signature motif; other site
1171376008362	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1171376008363	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1171376008364	Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG5519
1171376008365	Predicted ATP-binding protein involved in virulence [General function prediction only]; Region: COG3950
1171376008366	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1171376008367	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376008368	non-specific DNA binding site [nucleotide binding]; other site
1171376008369	salt bridge; other site
1171376008370	sequence-specific DNA binding site [nucleotide binding]; other site
1171376008371	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
1171376008372	Phosphotransferase system sorbitol-specific component IIC [Carbohydrate transport and metabolism]; Region: SrlA; COG3730
1171376008373	Phosphotransferase system sorbitol-specific component IIA [Carbohydrate transport and metabolism]; Region: SrlB; COG3731
1171376008374	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1171376008375	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1171376008376	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1171376008377	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1171376008378	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1171376008379	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1171376008380	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
1171376008381	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1171376008382	active site
1171376008383	dimer interface [polypeptide binding]; other site
1171376008384	magnesium binding site [ion binding]; other site
1171376008385	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
1171376008386	tetramer interface [polypeptide binding]; other site
1171376008387	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1171376008388	active site
1171376008389	Thermophilic glucose-6-phosphate isomerase and related metalloenzymes [Carbohydrate transport and metabolism / General function prediction only]; Region: COG2140
1171376008390	Glucose-6-phosphate isomerase (GPI); Region: GPI; pfam06560
1171376008391	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1171376008392	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1171376008393	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1171376008394	active site turn [active]
1171376008395	phosphorylation site [posttranslational modification]
1171376008396	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1171376008397	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1171376008398	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1171376008399	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
1171376008400	Integrase; Region: Integrase_1; pfam12835
1171376008401	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1171376008402	Integrase core domain; Region: rve; pfam00665
1171376008403	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1171376008404	DNA-binding interface [nucleotide binding]; DNA binding site
1171376008405	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3972
1171376008406	Family description; Region: UvrD_C_2; pfam13538
1171376008407	Transposase; Region: HTH_Tnp_1; cl17663
1171376008408	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1171376008409	putative transposase OrfB; Reviewed; Region: PHA02517
1171376008410	HTH-like domain; Region: HTH_21; pfam13276
1171376008411	Integrase core domain; Region: rve; pfam00665
1171376008412	Integrase core domain; Region: rve_2; pfam13333
1171376008413	Repressor of phase-1 flagellin; Region: Flag1_repress; pfam03614
1171376008414	flagellin; Validated; Region: PRK08026
1171376008415	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1171376008416	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
1171376008417	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1171376008418	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1171376008419	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1171376008420	catalytic residues [active]
1171376008421	catalytic nucleophile [active]
1171376008422	Presynaptic Site I dimer interface [polypeptide binding]; other site
1171376008423	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1171376008424	Synaptic Flat tetramer interface [polypeptide binding]; other site
1171376008425	Synaptic Site I dimer interface [polypeptide binding]; other site
1171376008426	DNA binding site [nucleotide binding]
1171376008427	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1171376008428	DNA-binding interface [nucleotide binding]; DNA binding site
1171376008429	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
1171376008430	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1171376008431	homodimer interface [polypeptide binding]; other site
1171376008432	active site
1171376008433	TDP-binding site; other site
1171376008434	acceptor substrate-binding pocket; other site
1171376008435	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1171376008436	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376008437	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1171376008438	Walker A/P-loop; other site
1171376008439	ATP binding site [chemical binding]; other site
1171376008440	Q-loop/lid; other site
1171376008441	ABC transporter signature motif; other site
1171376008442	Walker B; other site
1171376008443	D-loop; other site
1171376008444	H-loop/switch region; other site
1171376008445	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1171376008446	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1171376008447	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376008448	Walker A/P-loop; other site
1171376008449	ATP binding site [chemical binding]; other site
1171376008450	Q-loop/lid; other site
1171376008451	ABC transporter signature motif; other site
1171376008452	Walker B; other site
1171376008453	D-loop; other site
1171376008454	H-loop/switch region; other site
1171376008455	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1171376008456	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1171376008457	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1171376008458	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1171376008459	outer membrane receptor FepA; Provisional; Region: PRK13528
1171376008460	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1171376008461	N-terminal plug; other site
1171376008462	ligand-binding site [chemical binding]; other site
1171376008463	secreted effector protein PipB2; Provisional; Region: PRK15196
1171376008464	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1171376008465	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1171376008466	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1171376008467	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1171376008468	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1171376008469	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
1171376008470	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
1171376008471	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1171376008472	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1171376008473	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
1171376008474	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1171376008475	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1171376008476	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376008477	dimer interface [polypeptide binding]; other site
1171376008478	phosphorylation site [posttranslational modification]
1171376008479	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376008480	ATP binding site [chemical binding]; other site
1171376008481	Mg2+ binding site [ion binding]; other site
1171376008482	G-X-G motif; other site
1171376008483	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
1171376008484	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376008485	active site
1171376008486	phosphorylation site [posttranslational modification]
1171376008487	intermolecular recognition site; other site
1171376008488	dimerization interface [polypeptide binding]; other site
1171376008489	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376008490	DNA binding site [nucleotide binding]
1171376008491	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1171376008492	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
1171376008493	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
1171376008494	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
1171376008495	substrate binding pocket [chemical binding]; other site
1171376008496	active site
1171376008497	iron coordination sites [ion binding]; other site
1171376008498	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1171376008499	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1171376008500	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
1171376008501	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1171376008502	tetramerization interface [polypeptide binding]; other site
1171376008503	NAD(P) binding site [chemical binding]; other site
1171376008504	catalytic residues [active]
1171376008505	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
1171376008506	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1171376008507	inhibitor-cofactor binding pocket; inhibition site
1171376008508	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376008509	catalytic residue [active]
1171376008510	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
1171376008511	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
1171376008512	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376008513	DNA-binding site [nucleotide binding]; DNA binding site
1171376008514	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1171376008515	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1171376008516	bacterial OsmY and nodulation domain; Region: BON; smart00749
1171376008517	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1171376008518	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1171376008519	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1171376008520	dimerization interface [polypeptide binding]; other site
1171376008521	putative DNA binding site [nucleotide binding]; other site
1171376008522	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1171376008523	putative Zn2+ binding site [ion binding]; other site
1171376008524	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1171376008525	active site residue [active]
1171376008526	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1171376008527	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1171376008528	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1171376008529	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1171376008530	hypothetical protein; Provisional; Region: PRK10556
1171376008531	hypothetical protein; Provisional; Region: PRK10132
1171376008532	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1171376008533	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376008534	DNA-binding site [nucleotide binding]; DNA binding site
1171376008535	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376008536	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376008537	homodimer interface [polypeptide binding]; other site
1171376008538	catalytic residue [active]
1171376008539	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1171376008540	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1171376008541	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1171376008542	catalytic residues [active]
1171376008543	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1171376008544	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1171376008545	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1171376008546	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1171376008547	active site
1171376008548	dimer interface [polypeptide binding]; other site
1171376008549	catalytic residues [active]
1171376008550	effector binding site; other site
1171376008551	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1171376008552	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1171376008553	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1171376008554	dimer interface [polypeptide binding]; other site
1171376008555	putative radical transfer pathway; other site
1171376008556	diiron center [ion binding]; other site
1171376008557	tyrosyl radical; other site
1171376008558	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1171376008559	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1171376008560	Walker A/P-loop; other site
1171376008561	ATP binding site [chemical binding]; other site
1171376008562	Q-loop/lid; other site
1171376008563	ABC transporter signature motif; other site
1171376008564	Walker B; other site
1171376008565	D-loop; other site
1171376008566	H-loop/switch region; other site
1171376008567	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1171376008568	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1171376008569	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376008570	dimer interface [polypeptide binding]; other site
1171376008571	conserved gate region; other site
1171376008572	putative PBP binding loops; other site
1171376008573	ABC-ATPase subunit interface; other site
1171376008574	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1171376008575	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1171376008576	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1171376008577	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376008578	transcriptional repressor MprA; Provisional; Region: PRK10870
1171376008579	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1171376008580	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1171376008581	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1171376008582	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376008583	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1171376008584	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376008585	putative substrate translocation pore; other site
1171376008586	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376008587	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1171376008588	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1171376008589	glutamate--cysteine ligase; Provisional; Region: PRK02107
1171376008590	Predicted membrane protein [Function unknown]; Region: COG1238
1171376008591	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1171376008592	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376008593	motif II; other site
1171376008594	carbon storage regulator; Provisional; Region: PRK01712
1171376008595	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1171376008596	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1171376008597	motif 1; other site
1171376008598	active site
1171376008599	motif 2; other site
1171376008600	motif 3; other site
1171376008601	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1171376008602	DHHA1 domain; Region: DHHA1; pfam02272
1171376008603	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1171376008604	recombinase A; Provisional; Region: recA; PRK09354
1171376008605	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1171376008606	hexamer interface [polypeptide binding]; other site
1171376008607	Walker A motif; other site
1171376008608	ATP binding site [chemical binding]; other site
1171376008609	Walker B motif; other site
1171376008610	hypothetical protein; Validated; Region: PRK03661
1171376008611	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1171376008612	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1171376008613	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1171376008614	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
1171376008615	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1171376008616	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1171376008617	Nucleoside recognition; Region: Gate; pfam07670
1171376008618	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1171376008619	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1171376008620	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1171376008621	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1171376008622	putative NAD(P) binding site [chemical binding]; other site
1171376008623	active site
1171376008624	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1171376008625	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1171376008626	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1171376008627	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376008628	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1171376008629	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1171376008630	putative active site [active]
1171376008631	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1171376008632	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1171376008633	GAF domain; Region: GAF; pfam01590
1171376008634	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376008635	Walker A motif; other site
1171376008636	ATP binding site [chemical binding]; other site
1171376008637	Walker B motif; other site
1171376008638	arginine finger; other site
1171376008639	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1171376008640	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1171376008641	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1171376008642	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1171376008643	iron binding site [ion binding]; other site
1171376008644	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1171376008645	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1171376008646	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376008647	Acylphosphatase; Region: Acylphosphatase; pfam00708
1171376008648	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1171376008649	HypF finger; Region: zf-HYPF; pfam07503
1171376008650	HypF finger; Region: zf-HYPF; pfam07503
1171376008651	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1171376008652	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1171376008653	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1171376008654	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1171376008655	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1171376008656	nickel binding site [ion binding]; other site
1171376008657	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1171376008658	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1171376008659	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1171376008660	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1171376008661	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1171376008662	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1171376008663	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1171376008664	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1171376008665	NADH dehydrogenase; Region: NADHdh; cl00469
1171376008666	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1171376008667	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1171376008668	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1171376008669	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
1171376008670	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1171376008671	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1171376008672	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1171376008673	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1171376008674	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1171376008675	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1171376008676	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1171376008677	dimerization interface [polypeptide binding]; other site
1171376008678	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1171376008679	ATP binding site [chemical binding]; other site
1171376008680	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1171376008681	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1171376008682	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1171376008683	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376008684	Walker A motif; other site
1171376008685	ATP binding site [chemical binding]; other site
1171376008686	Walker B motif; other site
1171376008687	arginine finger; other site
1171376008688	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1171376008689	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1171376008690	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1171376008691	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1171376008692	metal binding site [ion binding]; metal-binding site
1171376008693	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1171376008694	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1171376008695	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1171376008696	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1171376008697	ABC-ATPase subunit  interface; other site
1171376008698	dimer interface [polypeptide binding]; other site
1171376008699	putative PBP binding regions; other site
1171376008700	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1171376008701	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1171376008702	ABC-ATPase subunit  interface; other site
1171376008703	dimer interface [polypeptide binding]; other site
1171376008704	putative PBP binding regions; other site
1171376008705	effector protein YopJ; Provisional; Region: PRK15371
1171376008706	transcriptional activator SprB; Provisional; Region: PRK15320
1171376008707	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1171376008708	transcriptional regulator SirC; Provisional; Region: PRK15044
1171376008709	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376008710	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
1171376008711	invasion protein OrgB; Provisional; Region: PRK15322
1171376008712	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
1171376008713	invasion protein OrgA; Provisional; Region: PRK15323
1171376008714	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
1171376008715	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
1171376008716	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
1171376008717	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
1171376008718	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
1171376008719	transcriptional regulator HilD; Provisional; Region: PRK15185
1171376008720	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376008721	invasion protein regulator; Provisional; Region: PRK12370
1171376008722	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376008723	DNA binding site [nucleotide binding]
1171376008724	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1171376008725	binding surface
1171376008726	TPR motif; other site
1171376008727	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1171376008728	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1171376008729	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1171376008730	catalytic residue [active]
1171376008731	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
1171376008732	SicP binding; Region: SicP-binding; pfam09119
1171376008733	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
1171376008734	switch II binding region; other site
1171376008735	Rac1 P-loop interaction site [polypeptide binding]; other site
1171376008736	GTP binding residues [chemical binding]; other site
1171376008737	switch I binding region; other site
1171376008738	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
1171376008739	active site
1171376008740	chaperone protein SicP; Provisional; Region: PRK15329
1171376008741	putative acyl carrier protein IacP; Validated; Region: PRK08172
1171376008742	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
1171376008743	cell invasion protein SipD; Provisional; Region: PRK15330
1171376008744	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
1171376008745	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
1171376008746	chaperone protein SicA; Provisional; Region: PRK15331
1171376008747	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1171376008748	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1171376008749	type III secretion system protein SpaS; Validated; Region: PRK08156
1171376008750	type III secretion system protein SpaR; Provisional; Region: PRK15332
1171376008751	type III secretion system protein SpaQ; Provisional; Region: PRK15333
1171376008752	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
1171376008753	type III secretion system protein SpaO; Validated; Region: PRK08158
1171376008754	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1171376008755	antigen presentation protein SpaN; Provisional; Region: PRK15334
1171376008756	Surface presentation of antigens protein; Region: SPAN; pfam02510
1171376008757	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
1171376008758	ATP synthase SpaL; Validated; Region: PRK08149
1171376008759	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1171376008760	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1171376008761	Walker A motif; other site
1171376008762	ATP binding site [chemical binding]; other site
1171376008763	Walker B motif; other site
1171376008764	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
1171376008765	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
1171376008766	type III secretion system protein InvA; Provisional; Region: PRK15337
1171376008767	type III secretion system regulator InvE; Provisional; Region: PRK15338
1171376008768	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
1171376008769	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
1171376008770	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1171376008771	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1171376008772	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1171376008773	transcriptional regulator InvF; Provisional; Region: PRK15340
1171376008774	InvH outer membrane lipoprotein; Region: InvH; pfam04741
1171376008775	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1171376008776	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1171376008777	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1171376008778	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1171376008779	active site
1171376008780	metal binding site [ion binding]; metal-binding site
1171376008781	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1171376008782	MutS domain I; Region: MutS_I; pfam01624
1171376008783	MutS domain II; Region: MutS_II; pfam05188
1171376008784	MutS domain III; Region: MutS_III; pfam05192
1171376008785	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1171376008786	Walker A/P-loop; other site
1171376008787	ATP binding site [chemical binding]; other site
1171376008788	Q-loop/lid; other site
1171376008789	ABC transporter signature motif; other site
1171376008790	Walker B; other site
1171376008791	D-loop; other site
1171376008792	H-loop/switch region; other site
1171376008793	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1171376008794	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376008795	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1171376008796	putative substrate translocation pore; other site
1171376008797	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376008798	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376008799	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1171376008800	putative effector binding pocket; other site
1171376008801	dimerization interface [polypeptide binding]; other site
1171376008802	GntP family permease; Region: GntP_permease; pfam02447
1171376008803	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1171376008804	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1171376008805	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
1171376008806	putative NAD(P) binding site [chemical binding]; other site
1171376008807	active site
1171376008808	putative substrate binding site [chemical binding]; other site
1171376008809	hypothetical protein; Provisional; Region: PRK09989
1171376008810	putative aldolase; Validated; Region: PRK08130
1171376008811	intersubunit interface [polypeptide binding]; other site
1171376008812	active site
1171376008813	Zn2+ binding site [ion binding]; other site
1171376008814	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1171376008815	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1171376008816	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1171376008817	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1171376008818	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1171376008819	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376008820	MarR family; Region: MarR_2; cl17246
1171376008821	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1171376008822	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1171376008823	Flavoprotein; Region: Flavoprotein; pfam02441
1171376008824	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1171376008825	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1171376008826	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1171376008827	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1171376008828	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1171376008829	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1171376008830	DNA binding residues [nucleotide binding]
1171376008831	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
1171376008832	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1171376008833	Peptidase family M23; Region: Peptidase_M23; pfam01551
1171376008834	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1171376008835	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376008836	S-adenosylmethionine binding site [chemical binding]; other site
1171376008837	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1171376008838	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1171376008839	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1171376008840	Permutation of conserved domain; other site
1171376008841	active site
1171376008842	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1171376008843	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1171376008844	homotrimer interaction site [polypeptide binding]; other site
1171376008845	zinc binding site [ion binding]; other site
1171376008846	CDP-binding sites; other site
1171376008847	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1171376008848	substrate binding site; other site
1171376008849	dimer interface; other site
1171376008850	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1171376008851	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1171376008852	potential frameshift: common BLAST hit: gi|409246601|ref|YP_006887305.1| Inner membrane protein ygbE
1171376008853	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1171376008854	ligand-binding site [chemical binding]; other site
1171376008855	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1171376008856	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1171376008857	CysD dimerization site [polypeptide binding]; other site
1171376008858	G1 box; other site
1171376008859	putative GEF interaction site [polypeptide binding]; other site
1171376008860	GTP/Mg2+ binding site [chemical binding]; other site
1171376008861	Switch I region; other site
1171376008862	G2 box; other site
1171376008863	G3 box; other site
1171376008864	Switch II region; other site
1171376008865	G4 box; other site
1171376008866	G5 box; other site
1171376008867	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1171376008868	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1171376008869	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1171376008870	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1171376008871	Active Sites [active]
1171376008872	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1171376008873	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1171376008874	metal binding site [ion binding]; metal-binding site
1171376008875	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
1171376008876	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
1171376008877	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
1171376008878	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
1171376008879	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
1171376008880	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
1171376008881	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09731
1171376008882	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
1171376008883	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1171376008884	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
1171376008885	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1171376008886	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
1171376008887	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1171376008888	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1171376008889	Active Sites [active]
1171376008890	sulfite reductase subunit beta; Provisional; Region: PRK13504
1171376008891	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1171376008892	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1171376008893	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1171376008894	Flavodoxin; Region: Flavodoxin_1; pfam00258
1171376008895	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1171376008896	FAD binding pocket [chemical binding]; other site
1171376008897	FAD binding motif [chemical binding]; other site
1171376008898	catalytic residues [active]
1171376008899	NAD binding pocket [chemical binding]; other site
1171376008900	phosphate binding motif [ion binding]; other site
1171376008901	beta-alpha-beta structure motif; other site
1171376008902	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1171376008903	active site
1171376008904	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
1171376008905	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1171376008906	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1171376008907	enolase; Provisional; Region: eno; PRK00077
1171376008908	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1171376008909	dimer interface [polypeptide binding]; other site
1171376008910	metal binding site [ion binding]; metal-binding site
1171376008911	substrate binding pocket [chemical binding]; other site
1171376008912	CTP synthetase; Validated; Region: pyrG; PRK05380
1171376008913	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1171376008914	Catalytic site [active]
1171376008915	active site
1171376008916	UTP binding site [chemical binding]; other site
1171376008917	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1171376008918	active site
1171376008919	putative oxyanion hole; other site
1171376008920	catalytic triad [active]
1171376008921	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1171376008922	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1171376008923	homodimer interface [polypeptide binding]; other site
1171376008924	metal binding site [ion binding]; metal-binding site
1171376008925	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1171376008926	homodimer interface [polypeptide binding]; other site
1171376008927	active site
1171376008928	putative chemical substrate binding site [chemical binding]; other site
1171376008929	metal binding site [ion binding]; metal-binding site
1171376008930	Fimbrial protein; Region: Fimbrial; cl01416
1171376008931	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1171376008932	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
1171376008933	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1171376008934	HD domain; Region: HD_4; pfam13328
1171376008935	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1171376008936	synthetase active site [active]
1171376008937	NTP binding site [chemical binding]; other site
1171376008938	metal binding site [ion binding]; metal-binding site
1171376008939	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1171376008940	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1171376008941	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1171376008942	TRAM domain; Region: TRAM; pfam01938
1171376008943	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376008944	S-adenosylmethionine binding site [chemical binding]; other site
1171376008945	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1171376008946	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1171376008947	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376008948	dimerization interface [polypeptide binding]; other site
1171376008949	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376008950	dimer interface [polypeptide binding]; other site
1171376008951	phosphorylation site [posttranslational modification]
1171376008952	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376008953	ATP binding site [chemical binding]; other site
1171376008954	Mg2+ binding site [ion binding]; other site
1171376008955	G-X-G motif; other site
1171376008956	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1171376008957	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376008958	active site
1171376008959	phosphorylation site [posttranslational modification]
1171376008960	intermolecular recognition site; other site
1171376008961	dimerization interface [polypeptide binding]; other site
1171376008962	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1171376008963	putative binding surface; other site
1171376008964	active site
1171376008965	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1171376008966	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1171376008967	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1171376008968	active site
1171376008969	tetramer interface [polypeptide binding]; other site
1171376008970	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1171376008971	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1171376008972	active site
1171376008973	tetramer interface [polypeptide binding]; other site
1171376008974	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376008975	D-galactonate transporter; Region: 2A0114; TIGR00893
1171376008976	putative substrate translocation pore; other site
1171376008977	flavodoxin; Provisional; Region: PRK08105
1171376008978	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1171376008979	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1171376008980	probable active site [active]
1171376008981	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
1171376008982	SecY interacting protein Syd; Provisional; Region: PRK04968
1171376008983	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1171376008984	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1171376008985	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1171376008986	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1171376008987	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1171376008988	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1171376008989	serine transporter; Region: stp; TIGR00814
1171376008990	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1171376008991	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1171376008992	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1171376008993	flap endonuclease-like protein; Provisional; Region: PRK09482
1171376008994	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1171376008995	active site
1171376008996	metal binding site 1 [ion binding]; metal-binding site
1171376008997	putative 5' ssDNA interaction site; other site
1171376008998	metal binding site 3; metal-binding site
1171376008999	metal binding site 2 [ion binding]; metal-binding site
1171376009000	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1171376009001	putative DNA binding site [nucleotide binding]; other site
1171376009002	putative metal binding site [ion binding]; other site
1171376009003	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1171376009004	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1171376009005	dimer interface [polypeptide binding]; other site
1171376009006	active site
1171376009007	metal binding site [ion binding]; metal-binding site
1171376009008	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1171376009009	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1171376009010	intersubunit interface [polypeptide binding]; other site
1171376009011	active site
1171376009012	Zn2+ binding site [ion binding]; other site
1171376009013	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1171376009014	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376009015	putative substrate translocation pore; other site
1171376009016	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1171376009017	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
1171376009018	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1171376009019	trimer interface [polypeptide binding]; other site
1171376009020	substrate binding site [chemical binding]; other site
1171376009021	Mn binding site [ion binding]; other site
1171376009022	L-fuculokinase; Provisional; Region: PRK10331
1171376009023	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1171376009024	nucleotide binding site [chemical binding]; other site
1171376009025	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
1171376009026	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1171376009027	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1171376009028	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376009029	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1171376009030	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1171376009031	hypothetical protein; Provisional; Region: PRK10873
1171376009032	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1171376009033	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376009034	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1171376009035	dimerization interface [polypeptide binding]; other site
1171376009036	substrate binding pocket [chemical binding]; other site
1171376009037	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1171376009038	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1171376009039	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1171376009040	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1171376009041	catalytic residue [active]
1171376009042	CsdA-binding activator; Provisional; Region: PRK15019
1171376009043	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1171376009044	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1171376009045	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1171376009046	putative ATP binding site [chemical binding]; other site
1171376009047	putative substrate interface [chemical binding]; other site
1171376009048	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1171376009049	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1171376009050	MltA specific insert domain; Region: MltA; pfam03562
1171376009051	3D domain; Region: 3D; pfam06725
1171376009052	AMIN domain; Region: AMIN; pfam11741
1171376009053	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1171376009054	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1171376009055	active site
1171376009056	metal binding site [ion binding]; metal-binding site
1171376009057	N-acetylglutamate synthase; Validated; Region: PRK05279
1171376009058	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1171376009059	putative feedback inhibition sensing region; other site
1171376009060	putative nucleotide binding site [chemical binding]; other site
1171376009061	putative substrate binding site [chemical binding]; other site
1171376009062	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376009063	Coenzyme A binding pocket [chemical binding]; other site
1171376009064	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1171376009065	AAA domain; Region: AAA_30; pfam13604
1171376009066	Family description; Region: UvrD_C_2; pfam13538
1171376009067	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1171376009068	protease3; Provisional; Region: PRK15101
1171376009069	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1171376009070	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1171376009071	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1171376009072	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1171376009073	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1171376009074	hypothetical protein; Provisional; Region: PRK10332
1171376009075	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1171376009076	hypothetical protein; Provisional; Region: PRK11521
1171376009077	hypothetical protein; Provisional; Region: PRK10557
1171376009078	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1171376009079	hypothetical protein; Provisional; Region: PRK10506
1171376009080	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1171376009081	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1171376009082	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1171376009083	dimerization interface [polypeptide binding]; other site
1171376009084	active site
1171376009085	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1171376009086	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1171376009087	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1171376009088	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1171376009089	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1171376009090	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1171376009091	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1171376009092	putative active site [active]
1171376009093	Ap4A binding site [chemical binding]; other site
1171376009094	nudix motif; other site
1171376009095	putative metal binding site [ion binding]; other site
1171376009096	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1171376009097	putative DNA-binding cleft [nucleotide binding]; other site
1171376009098	putative DNA clevage site; other site
1171376009099	molecular lever; other site
1171376009100	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1171376009101	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1171376009102	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1171376009103	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1171376009104	active site
1171376009105	catalytic tetrad [active]
1171376009106	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1171376009107	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376009108	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1171376009109	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1171376009110	putative acyl-acceptor binding pocket; other site
1171376009111	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1171376009112	acyl-activating enzyme (AAE) consensus motif; other site
1171376009113	putative AMP binding site [chemical binding]; other site
1171376009114	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1171376009115	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376009116	DNA binding site [nucleotide binding]
1171376009117	domain linker motif; other site
1171376009118	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1171376009119	dimerization interface (closed form) [polypeptide binding]; other site
1171376009120	ligand binding site [chemical binding]; other site
1171376009121	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1171376009122	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376009123	DNA binding site [nucleotide binding]
1171376009124	domain linker motif; other site
1171376009125	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1171376009126	dimerization interface (closed form) [polypeptide binding]; other site
1171376009127	ligand binding site [chemical binding]; other site
1171376009128	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1171376009129	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1171376009130	active site
1171376009131	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1171376009132	substrate binding site [chemical binding]; other site
1171376009133	catalytic residues [active]
1171376009134	dimer interface [polypeptide binding]; other site
1171376009135	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1171376009136	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376009137	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376009138	dimerization interface [polypeptide binding]; other site
1171376009139	putative racemase; Provisional; Region: PRK10200
1171376009140	aspartate racemase; Region: asp_race; TIGR00035
1171376009141	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1171376009142	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376009143	putative substrate translocation pore; other site
1171376009144	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376009145	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1171376009146	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1171376009147	NADP binding site [chemical binding]; other site
1171376009148	homodimer interface [polypeptide binding]; other site
1171376009149	active site
1171376009150	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1171376009151	putative acyltransferase; Provisional; Region: PRK05790
1171376009152	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1171376009153	dimer interface [polypeptide binding]; other site
1171376009154	active site
1171376009155	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376009156	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376009157	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1171376009158	dimerization interface [polypeptide binding]; other site
1171376009159	Predicted membrane protein [Function unknown]; Region: COG4125
1171376009160	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1171376009161	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1171376009162	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1171376009163	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1171376009164	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1171376009165	putative metal binding site [ion binding]; other site
1171376009166	putative homodimer interface [polypeptide binding]; other site
1171376009167	putative homotetramer interface [polypeptide binding]; other site
1171376009168	putative homodimer-homodimer interface [polypeptide binding]; other site
1171376009169	putative allosteric switch controlling residues; other site
1171376009170	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
1171376009171	transcriptional activator SprB; Provisional; Region: PRK15320
1171376009172	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14600
1171376009173	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
1171376009174	Fimbrial protein; Region: Fimbrial; pfam00419
1171376009175	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
1171376009176	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376009177	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376009178	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
1171376009179	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376009180	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376009181	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376009182	fimbrial protein StdA; Provisional; Region: PRK15210
1171376009183	hypothetical protein; Provisional; Region: PRK10316
1171376009184	YfdX protein; Region: YfdX; pfam10938
1171376009185	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1171376009186	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1171376009187	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1171376009188	oligomeric interface; other site
1171376009189	putative active site [active]
1171376009190	homodimer interface [polypeptide binding]; other site
1171376009191	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1171376009192	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1171376009193	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
1171376009194	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1171376009195	Peptidase family M23; Region: Peptidase_M23; pfam01551
1171376009196	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1171376009197	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1171376009198	active site
1171376009199	metal binding site [ion binding]; metal-binding site
1171376009200	nudix motif; other site
1171376009201	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1171376009202	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1171376009203	dimer interface [polypeptide binding]; other site
1171376009204	putative anticodon binding site; other site
1171376009205	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1171376009206	motif 1; other site
1171376009207	active site
1171376009208	motif 2; other site
1171376009209	motif 3; other site
1171376009210	potential frameshift: common BLAST hit: gi|197363916|ref|YP_002143553.1| peptide chain release factor 2
1171376009211	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1171376009212	DHH family; Region: DHH; pfam01368
1171376009213	DHHA1 domain; Region: DHHA1; pfam02272
1171376009214	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1171376009215	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1171376009216	dimerization domain [polypeptide binding]; other site
1171376009217	dimer interface [polypeptide binding]; other site
1171376009218	catalytic residues [active]
1171376009219	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1171376009220	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1171376009221	active site
1171376009222	Int/Topo IB signature motif; other site
1171376009223	flavodoxin FldB; Provisional; Region: PRK12359
1171376009224	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1171376009225	hypothetical protein; Provisional; Region: PRK10878
1171376009226	putative global regulator; Reviewed; Region: PRK09559
1171376009227	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1171376009228	hemolysin; Provisional; Region: PRK15087
1171376009229	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1171376009230	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1171376009231	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1171376009232	beta-galactosidase; Region: BGL; TIGR03356
1171376009233	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
1171376009234	glycine dehydrogenase; Provisional; Region: PRK05367
1171376009235	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1171376009236	tetramer interface [polypeptide binding]; other site
1171376009237	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376009238	catalytic residue [active]
1171376009239	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1171376009240	tetramer interface [polypeptide binding]; other site
1171376009241	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376009242	catalytic residue [active]
1171376009243	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1171376009244	lipoyl attachment site [posttranslational modification]; other site
1171376009245	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1171376009246	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1171376009247	oxidoreductase; Provisional; Region: PRK08013
1171376009248	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1171376009249	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1171376009250	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1171376009251	proline aminopeptidase P II; Provisional; Region: PRK10879
1171376009252	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1171376009253	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1171376009254	active site
1171376009255	hypothetical protein; Reviewed; Region: PRK01736
1171376009256	Z-ring-associated protein; Provisional; Region: PRK10972
1171376009257	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1171376009258	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1171376009259	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1171376009260	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1171376009261	ligand binding site [chemical binding]; other site
1171376009262	NAD binding site [chemical binding]; other site
1171376009263	tetramer interface [polypeptide binding]; other site
1171376009264	catalytic site [active]
1171376009265	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1171376009266	L-serine binding site [chemical binding]; other site
1171376009267	ACT domain interface; other site
1171376009268	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1171376009269	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1171376009270	active site
1171376009271	dimer interface [polypeptide binding]; other site
1171376009272	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1171376009273	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376009274	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1171376009275	putative dimerization interface [polypeptide binding]; other site
1171376009276	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1171376009277	oxidative stress defense protein; Provisional; Region: PRK11087
1171376009278	arginine exporter protein; Provisional; Region: PRK09304
1171376009279	mechanosensitive channel MscS; Provisional; Region: PRK10334
1171376009280	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1171376009281	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1171376009282	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1171376009283	active site
1171376009284	intersubunit interface [polypeptide binding]; other site
1171376009285	zinc binding site [ion binding]; other site
1171376009286	Na+ binding site [ion binding]; other site
1171376009287	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1171376009288	Phosphoglycerate kinase; Region: PGK; pfam00162
1171376009289	substrate binding site [chemical binding]; other site
1171376009290	hinge regions; other site
1171376009291	ADP binding site [chemical binding]; other site
1171376009292	catalytic site [active]
1171376009293	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1171376009294	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1171376009295	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1171376009296	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1171376009297	trimer interface [polypeptide binding]; other site
1171376009298	putative Zn binding site [ion binding]; other site
1171376009299	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1171376009300	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1171376009301	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1171376009302	Walker A/P-loop; other site
1171376009303	ATP binding site [chemical binding]; other site
1171376009304	Q-loop/lid; other site
1171376009305	ABC transporter signature motif; other site
1171376009306	Walker B; other site
1171376009307	D-loop; other site
1171376009308	H-loop/switch region; other site
1171376009309	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1171376009310	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1171376009311	Walker A/P-loop; other site
1171376009312	ATP binding site [chemical binding]; other site
1171376009313	Q-loop/lid; other site
1171376009314	ABC transporter signature motif; other site
1171376009315	Walker B; other site
1171376009316	D-loop; other site
1171376009317	H-loop/switch region; other site
1171376009318	transketolase; Reviewed; Region: PRK12753
1171376009319	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1171376009320	TPP-binding site [chemical binding]; other site
1171376009321	dimer interface [polypeptide binding]; other site
1171376009322	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1171376009323	PYR/PP interface [polypeptide binding]; other site
1171376009324	dimer interface [polypeptide binding]; other site
1171376009325	TPP binding site [chemical binding]; other site
1171376009326	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1171376009327	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1171376009328	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1171376009329	agmatinase; Region: agmatinase; TIGR01230
1171376009330	oligomer interface [polypeptide binding]; other site
1171376009331	putative active site [active]
1171376009332	Mn binding site [ion binding]; other site
1171376009333	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1171376009334	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1171376009335	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
1171376009336	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1171376009337	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1171376009338	putative NAD(P) binding site [chemical binding]; other site
1171376009339	catalytic Zn binding site [ion binding]; other site
1171376009340	structural Zn binding site [ion binding]; other site
1171376009341	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1171376009342	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1171376009343	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1171376009344	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1171376009345	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1171376009346	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376009347	DNA-binding site [nucleotide binding]; DNA binding site
1171376009348	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1171376009349	DNA phosphorothioation-dependent restriction protein DptH; Region: dnd_assoc_2; TIGR03237
1171376009350	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1171376009351	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1171376009352	dimer interface [polypeptide binding]; other site
1171376009353	active site
1171376009354	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1171376009355	catalytic residues [active]
1171376009356	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1171376009357	Virulence promoting factor; Region: YqgB; pfam11036
1171376009358	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
1171376009359	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1171376009360	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1171376009361	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1171376009362	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1171376009363	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1171376009364	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376009365	putative substrate translocation pore; other site
1171376009366	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376009367	hypothetical protein; Provisional; Region: PRK04860
1171376009368	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1171376009369	DNA-specific endonuclease I; Provisional; Region: PRK15137
1171376009370	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1171376009371	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1171376009372	RNA methyltransferase, RsmE family; Region: TIGR00046
1171376009373	glutathione synthetase; Provisional; Region: PRK05246
1171376009374	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1171376009375	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1171376009376	hypothetical protein; Validated; Region: PRK00228
1171376009377	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1171376009378	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1171376009379	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1171376009380	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1171376009381	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1171376009382	Walker A motif; other site
1171376009383	ATP binding site [chemical binding]; other site
1171376009384	Walker B motif; other site
1171376009385	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1171376009386	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1171376009387	catalytic residue [active]
1171376009388	YGGT family; Region: YGGT; pfam02325
1171376009389	YGGT family; Region: YGGT; pfam02325
1171376009390	hypothetical protein; Validated; Region: PRK05090
1171376009391	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1171376009392	active site
1171376009393	dimerization interface [polypeptide binding]; other site
1171376009394	HemN family oxidoreductase; Provisional; Region: PRK05660
1171376009395	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376009396	FeS/SAM binding site; other site
1171376009397	HemN C-terminal domain; Region: HemN_C; pfam06969
1171376009398	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
1171376009399	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
1171376009400	homodimer interface [polypeptide binding]; other site
1171376009401	active site
1171376009402	hypothetical protein; Provisional; Region: PRK10626
1171376009403	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1171376009404	hypothetical protein; Provisional; Region: PRK11702
1171376009405	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1171376009406	adenine DNA glycosylase; Provisional; Region: PRK10880
1171376009407	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1171376009408	minor groove reading motif; other site
1171376009409	helix-hairpin-helix signature motif; other site
1171376009410	substrate binding pocket [chemical binding]; other site
1171376009411	active site
1171376009412	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1171376009413	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1171376009414	DNA binding and oxoG recognition site [nucleotide binding]
1171376009415	oxidative damage protection protein; Provisional; Region: PRK05408
1171376009416	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1171376009417	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1171376009418	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1171376009419	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1171376009420	catalytic residue [active]
1171376009421	nucleoside transporter; Region: 2A0110; TIGR00889
1171376009422	ornithine decarboxylase; Provisional; Region: PRK13578
1171376009423	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1171376009424	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1171376009425	homodimer interface [polypeptide binding]; other site
1171376009426	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376009427	catalytic residue [active]
1171376009428	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1171376009429	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
1171376009430	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
1171376009431	dimer interface [polypeptide binding]; other site
1171376009432	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1171376009433	metal binding site [ion binding]; metal-binding site
1171376009434	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
1171376009435	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1171376009436	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1171376009437	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
1171376009438	putative active site [active]
1171376009439	putative catalytic site [active]
1171376009440	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1171376009441	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1171376009442	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376009443	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
1171376009444	putative dimerization interface [polypeptide binding]; other site
1171376009445	putative substrate binding pocket [chemical binding]; other site
1171376009446	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1171376009447	Sulfatase; Region: Sulfatase; pfam00884
1171376009448	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1171376009449	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376009450	FeS/SAM binding site; other site
1171376009451	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1171376009452	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1171376009453	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376009454	DNA binding residues [nucleotide binding]
1171376009455	dimerization interface [polypeptide binding]; other site
1171376009456	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
1171376009457	Amino acid permease; Region: AA_permease_2; pfam13520
1171376009458	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
1171376009459	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1171376009460	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1171376009461	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
1171376009462	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1171376009463	NAD(P) binding site [chemical binding]; other site
1171376009464	catalytic residues [active]
1171376009465	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
1171376009466	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1171376009467	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1171376009468	active site
1171376009469	catalytic site [active]
1171376009470	Zn binding site [ion binding]; other site
1171376009471	tetramer interface [polypeptide binding]; other site
1171376009472	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1171376009473	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
1171376009474	putative active site [active]
1171376009475	catalytic triad [active]
1171376009476	putative dimer interface [polypeptide binding]; other site
1171376009477	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376009478	D-galactonate transporter; Region: 2A0114; TIGR00893
1171376009479	putative substrate translocation pore; other site
1171376009480	mannonate dehydratase; Provisional; Region: PRK03906
1171376009481	mannonate dehydratase; Region: uxuA; TIGR00695
1171376009482	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1171376009483	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1171376009484	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1171376009485	Glucuronate isomerase; Region: UxaC; pfam02614
1171376009486	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1171376009487	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1171376009488	dimer interface [polypeptide binding]; other site
1171376009489	putative CheW interface [polypeptide binding]; other site
1171376009490	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1171376009491	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1171376009492	CHAP domain; Region: CHAP; pfam05257
1171376009493	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1171376009494	putative S-transferase; Provisional; Region: PRK11752
1171376009495	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1171376009496	C-terminal domain interface [polypeptide binding]; other site
1171376009497	GSH binding site (G-site) [chemical binding]; other site
1171376009498	dimer interface [polypeptide binding]; other site
1171376009499	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1171376009500	dimer interface [polypeptide binding]; other site
1171376009501	N-terminal domain interface [polypeptide binding]; other site
1171376009502	active site
1171376009503	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1171376009504	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
1171376009505	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1171376009506	putative ligand binding residues [chemical binding]; other site
1171376009507	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1171376009508	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
1171376009509	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1171376009510	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
1171376009511	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
1171376009512	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1171376009513	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1171376009514	putative substrate-binding site; other site
1171376009515	nickel binding site [ion binding]; other site
1171376009516	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1171376009517	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1171376009518	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
1171376009519	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1171376009520	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
1171376009521	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1171376009522	hydrogenase 2 small subunit; Provisional; Region: PRK10468
1171376009523	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1171376009524	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1171376009525	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
1171376009526	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1171376009527	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376009528	dimerization interface [polypeptide binding]; other site
1171376009529	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1171376009530	dimer interface [polypeptide binding]; other site
1171376009531	putative CheW interface [polypeptide binding]; other site
1171376009532	hypothetical protein; Provisional; Region: PRK05208
1171376009533	oxidoreductase; Provisional; Region: PRK07985
1171376009534	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1171376009535	NAD binding site [chemical binding]; other site
1171376009536	metal binding site [ion binding]; metal-binding site
1171376009537	active site
1171376009538	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1171376009539	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1171376009540	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1171376009541	cystathionine beta-lyase; Provisional; Region: PRK08114
1171376009542	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1171376009543	homodimer interface [polypeptide binding]; other site
1171376009544	substrate-cofactor binding pocket; other site
1171376009545	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376009546	catalytic residue [active]
1171376009547	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1171376009548	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1171376009549	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1171376009550	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1171376009551	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376009552	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376009553	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1171376009554	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1171376009555	dimer interface [polypeptide binding]; other site
1171376009556	active site
1171376009557	metal binding site [ion binding]; metal-binding site
1171376009558	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1171376009559	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1171376009560	active site
1171376009561	catalytic tetrad [active]
1171376009562	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1171376009563	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1171376009564	transmembrane helices; other site
1171376009565	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1171376009566	nucleotide binding site/active site [active]
1171376009567	catalytic residue [active]
1171376009568	hypothetical protein; Provisional; Region: PRK01254
1171376009569	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1171376009570	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1171376009571	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1171376009572	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1171376009573	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1171376009574	DctM-like transporters; Region: DctM; pfam06808
1171376009575	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
1171376009576	FtsI repressor; Provisional; Region: PRK10883
1171376009577	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1171376009578	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1171376009579	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1171376009580	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1171376009581	putative acyl-acceptor binding pocket; other site
1171376009582	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
1171376009583	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1171376009584	CAP-like domain; other site
1171376009585	active site
1171376009586	primary dimer interface [polypeptide binding]; other site
1171376009587	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1171376009588	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1171376009589	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376009590	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1171376009591	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1171376009592	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1171376009593	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376009594	active site
1171376009595	phosphorylation site [posttranslational modification]
1171376009596	intermolecular recognition site; other site
1171376009597	dimerization interface [polypeptide binding]; other site
1171376009598	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376009599	DNA binding site [nucleotide binding]
1171376009600	sensor protein QseC; Provisional; Region: PRK10337
1171376009601	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1171376009602	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376009603	dimer interface [polypeptide binding]; other site
1171376009604	phosphorylation site [posttranslational modification]
1171376009605	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376009606	ATP binding site [chemical binding]; other site
1171376009607	Mg2+ binding site [ion binding]; other site
1171376009608	G-X-G motif; other site
1171376009609	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1171376009610	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1171376009611	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1171376009612	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376009613	ATP binding site [chemical binding]; other site
1171376009614	Mg2+ binding site [ion binding]; other site
1171376009615	G-X-G motif; other site
1171376009616	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1171376009617	anchoring element; other site
1171376009618	dimer interface [polypeptide binding]; other site
1171376009619	ATP binding site [chemical binding]; other site
1171376009620	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1171376009621	active site
1171376009622	metal binding site [ion binding]; metal-binding site
1171376009623	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1171376009624	esterase YqiA; Provisional; Region: PRK11071
1171376009625	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1171376009626	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1171376009627	active site
1171376009628	metal binding site [ion binding]; metal-binding site
1171376009629	hexamer interface [polypeptide binding]; other site
1171376009630	putative dehydrogenase; Provisional; Region: PRK11039
1171376009631	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1171376009632	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1171376009633	dimer interface [polypeptide binding]; other site
1171376009634	ADP-ribose binding site [chemical binding]; other site
1171376009635	active site
1171376009636	nudix motif; other site
1171376009637	metal binding site [ion binding]; metal-binding site
1171376009638	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1171376009639	hypothetical protein; Provisional; Region: PRK11653
1171376009640	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1171376009641	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1171376009642	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1171376009643	putative active site [active]
1171376009644	metal binding site [ion binding]; metal-binding site
1171376009645	zinc transporter ZupT; Provisional; Region: PRK04201
1171376009646	ZIP Zinc transporter; Region: Zip; pfam02535
1171376009647	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
1171376009648	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1171376009649	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1171376009650	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1171376009651	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1171376009652	catalytic residues [active]
1171376009653	hinge region; other site
1171376009654	alpha helical domain; other site
1171376009655	putative disulfide oxidoreductase; Provisional; Region: PRK04307
1171376009656	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1171376009657	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1171376009658	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1171376009659	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
1171376009660	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
1171376009661	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1171376009662	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1171376009663	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1171376009664	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1171376009665	putative ribose interaction site [chemical binding]; other site
1171376009666	putative ADP binding site [chemical binding]; other site
1171376009667	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1171376009668	active site
1171376009669	nucleotide binding site [chemical binding]; other site
1171376009670	HIGH motif; other site
1171376009671	KMSKS motif; other site
1171376009672	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1171376009673	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1171376009674	metal binding triad; other site
1171376009675	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1171376009676	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1171376009677	metal binding triad; other site
1171376009678	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1171376009679	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1171376009680	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1171376009681	putative active site [active]
1171376009682	putative metal binding residues [ion binding]; other site
1171376009683	signature motif; other site
1171376009684	putative triphosphate binding site [ion binding]; other site
1171376009685	CHAD domain; Region: CHAD; pfam05235
1171376009686	SH3 domain-containing protein; Provisional; Region: PRK10884
1171376009687	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1171376009688	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1171376009689	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1171376009690	active site
1171376009691	NTP binding site [chemical binding]; other site
1171376009692	metal binding triad [ion binding]; metal-binding site
1171376009693	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1171376009694	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1171376009695	Zn2+ binding site [ion binding]; other site
1171376009696	Mg2+ binding site [ion binding]; other site
1171376009697	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1171376009698	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1171376009699	homooctamer interface [polypeptide binding]; other site
1171376009700	active site
1171376009701	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1171376009702	UGMP family protein; Validated; Region: PRK09604
1171376009703	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1171376009704	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1171376009705	DNA primase; Validated; Region: dnaG; PRK05667
1171376009706	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1171376009707	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1171376009708	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1171376009709	active site
1171376009710	metal binding site [ion binding]; metal-binding site
1171376009711	interdomain interaction site; other site
1171376009712	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1171376009713	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1171376009714	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1171376009715	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1171376009716	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1171376009717	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1171376009718	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1171376009719	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1171376009720	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1171376009721	DNA binding residues [nucleotide binding]
1171376009722	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1171376009723	active site
1171376009724	SUMO-1 interface [polypeptide binding]; other site
1171376009725	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1171376009726	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1171376009727	FAD binding pocket [chemical binding]; other site
1171376009728	FAD binding motif [chemical binding]; other site
1171376009729	phosphate binding motif [ion binding]; other site
1171376009730	NAD binding pocket [chemical binding]; other site
1171376009731	Predicted transcriptional regulators [Transcription]; Region: COG1695
1171376009732	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1171376009733	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1171376009734	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376009735	dimerization interface [polypeptide binding]; other site
1171376009736	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1171376009737	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1171376009738	dimer interface [polypeptide binding]; other site
1171376009739	putative CheW interface [polypeptide binding]; other site
1171376009740	PAS fold; Region: PAS_3; pfam08447
1171376009741	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1171376009742	putative active site [active]
1171376009743	heme pocket [chemical binding]; other site
1171376009744	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1171376009745	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1171376009746	dimer interface [polypeptide binding]; other site
1171376009747	putative CheW interface [polypeptide binding]; other site
1171376009748	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
1171376009749	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1171376009750	inhibitor-cofactor binding pocket; inhibition site
1171376009751	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376009752	catalytic residue [active]
1171376009753	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1171376009754	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1171376009755	active site
1171376009756	FMN binding site [chemical binding]; other site
1171376009757	2,4-decadienoyl-CoA binding site; other site
1171376009758	catalytic residue [active]
1171376009759	4Fe-4S cluster binding site [ion binding]; other site
1171376009760	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1171376009761	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1171376009762	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1171376009763	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376009764	S-adenosylmethionine binding site [chemical binding]; other site
1171376009765	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1171376009766	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1171376009767	putative active site [active]
1171376009768	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1171376009769	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1171376009770	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1171376009771	serine/threonine transporter SstT; Provisional; Region: PRK13628
1171376009772	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1171376009773	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1171376009774	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1171376009775	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1171376009776	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1171376009777	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1171376009778	Predicted membrane protein [Function unknown]; Region: COG5393
1171376009779	YqjK-like protein; Region: YqjK; pfam13997
1171376009780	Predicted membrane protein [Function unknown]; Region: COG2259
1171376009781	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1171376009782	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1171376009783	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1171376009784	putative dimer interface [polypeptide binding]; other site
1171376009785	N-terminal domain interface [polypeptide binding]; other site
1171376009786	putative substrate binding pocket (H-site) [chemical binding]; other site
1171376009787	Predicted membrane protein [Function unknown]; Region: COG3152
1171376009788	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376009789	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1171376009790	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1171376009791	dimerization interface [polypeptide binding]; other site
1171376009792	Pirin-related protein [General function prediction only]; Region: COG1741
1171376009793	Pirin; Region: Pirin; pfam02678
1171376009794	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1171376009795	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1171376009796	serine transporter; Region: stp; TIGR00814
1171376009797	L-serine dehydratase TdcG; Provisional; Region: PRK15040
1171376009798	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1171376009799	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1171376009800	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1171376009801	Pyruvate formate lyase 1; Region: PFL1; cd01678
1171376009802	coenzyme A binding site [chemical binding]; other site
1171376009803	active site
1171376009804	catalytic residues [active]
1171376009805	glycine loop; other site
1171376009806	propionate/acetate kinase; Provisional; Region: PRK12379
1171376009807	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
1171376009808	threonine/serine transporter TdcC; Provisional; Region: PRK13629
1171376009809	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1171376009810	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1171376009811	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1171376009812	tetramer interface [polypeptide binding]; other site
1171376009813	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376009814	catalytic residue [active]
1171376009815	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1171376009816	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376009817	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1171376009818	putative substrate binding pocket [chemical binding]; other site
1171376009819	putative dimerization interface [polypeptide binding]; other site
1171376009820	glycerate kinase I; Provisional; Region: PRK10342
1171376009821	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1171376009822	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1171376009823	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1171376009824	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1171376009825	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1171376009826	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1171376009827	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376009828	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1171376009829	substrate binding site [chemical binding]; other site
1171376009830	ATP binding site [chemical binding]; other site
1171376009831	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1171376009832	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1171376009833	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376009834	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1171376009835	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1171376009836	intersubunit interface [polypeptide binding]; other site
1171376009837	active site
1171376009838	zinc binding site [ion binding]; other site
1171376009839	Na+ binding site [ion binding]; other site
1171376009840	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1171376009841	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1171376009842	putative substrate binding site [chemical binding]; other site
1171376009843	putative ATP binding site [chemical binding]; other site
1171376009844	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1171376009845	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1171376009846	active site
1171376009847	P-loop; other site
1171376009848	phosphorylation site [posttranslational modification]
1171376009849	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1171376009850	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376009851	active site
1171376009852	phosphorylation site [posttranslational modification]
1171376009853	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1171376009854	dimerization domain swap beta strand [polypeptide binding]; other site
1171376009855	regulatory protein interface [polypeptide binding]; other site
1171376009856	active site
1171376009857	regulatory phosphorylation site [posttranslational modification]; other site
1171376009858	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
1171376009859	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376009860	active site
1171376009861	phosphorylation site [posttranslational modification]
1171376009862	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1171376009863	active site
1171376009864	P-loop; other site
1171376009865	phosphorylation site [posttranslational modification]
1171376009866	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1171376009867	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1171376009868	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1171376009869	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1171376009870	putative NAD(P) binding site [chemical binding]; other site
1171376009871	catalytic Zn binding site [ion binding]; other site
1171376009872	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1171376009873	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1171376009874	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376009875	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1171376009876	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1171376009877	putative SAM binding site [chemical binding]; other site
1171376009878	putative homodimer interface [polypeptide binding]; other site
1171376009879	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1171376009880	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
1171376009881	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1171376009882	putative ligand binding site [chemical binding]; other site
1171376009883	TIGR00252 family protein; Region: TIGR00252
1171376009884	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1171376009885	dimer interface [polypeptide binding]; other site
1171376009886	active site
1171376009887	outer membrane lipoprotein; Provisional; Region: PRK11023
1171376009888	BON domain; Region: BON; pfam04972
1171376009889	BON domain; Region: BON; pfam04972
1171376009890	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1171376009891	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1171376009892	NAD binding site [chemical binding]; other site
1171376009893	active site
1171376009894	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1171376009895	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1171376009896	proposed catalytic triad [active]
1171376009897	conserved cys residue [active]
1171376009898	hypothetical protein; Provisional; Region: PRK03467
1171376009899	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1171376009900	GIY-YIG motif/motif A; other site
1171376009901	putative active site [active]
1171376009902	putative metal binding site [ion binding]; other site
1171376009903	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1171376009904	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376009905	Coenzyme A binding pocket [chemical binding]; other site
1171376009906	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1171376009907	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1171376009908	Peptidase family U32; Region: Peptidase_U32; pfam01136
1171376009909	putative protease; Provisional; Region: PRK15447
1171376009910	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1171376009911	hypothetical protein; Provisional; Region: PRK10508
1171376009912	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1171376009913	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1171376009914	tryptophan permease; Provisional; Region: PRK10483
1171376009915	aromatic amino acid transport protein; Region: araaP; TIGR00837
1171376009916	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1171376009917	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1171376009918	ATP binding site [chemical binding]; other site
1171376009919	Mg++ binding site [ion binding]; other site
1171376009920	motif III; other site
1171376009921	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376009922	nucleotide binding region [chemical binding]; other site
1171376009923	ATP-binding site [chemical binding]; other site
1171376009924	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1171376009925	putative RNA binding site [nucleotide binding]; other site
1171376009926	lipoprotein NlpI; Provisional; Region: PRK11189
1171376009927	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1171376009928	binding surface
1171376009929	TPR motif; other site
1171376009930	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1171376009931	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1171376009932	RNase E interface [polypeptide binding]; other site
1171376009933	trimer interface [polypeptide binding]; other site
1171376009934	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1171376009935	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1171376009936	RNase E interface [polypeptide binding]; other site
1171376009937	trimer interface [polypeptide binding]; other site
1171376009938	active site
1171376009939	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1171376009940	putative nucleic acid binding region [nucleotide binding]; other site
1171376009941	G-X-X-G motif; other site
1171376009942	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1171376009943	RNA binding site [nucleotide binding]; other site
1171376009944	domain interface; other site
1171376009945	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1171376009946	16S/18S rRNA binding site [nucleotide binding]; other site
1171376009947	S13e-L30e interaction site [polypeptide binding]; other site
1171376009948	25S rRNA binding site [nucleotide binding]; other site
1171376009949	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1171376009950	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1171376009951	RNA binding site [nucleotide binding]; other site
1171376009952	active site
1171376009953	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1171376009954	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1171376009955	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1171376009956	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1171376009957	translation initiation factor IF-2; Region: IF-2; TIGR00487
1171376009958	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1171376009959	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1171376009960	G1 box; other site
1171376009961	putative GEF interaction site [polypeptide binding]; other site
1171376009962	GTP/Mg2+ binding site [chemical binding]; other site
1171376009963	Switch I region; other site
1171376009964	G2 box; other site
1171376009965	G3 box; other site
1171376009966	Switch II region; other site
1171376009967	G4 box; other site
1171376009968	G5 box; other site
1171376009969	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1171376009970	Translation-initiation factor 2; Region: IF-2; pfam11987
1171376009971	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1171376009972	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1171376009973	NusA N-terminal domain; Region: NusA_N; pfam08529
1171376009974	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1171376009975	RNA binding site [nucleotide binding]; other site
1171376009976	homodimer interface [polypeptide binding]; other site
1171376009977	NusA-like KH domain; Region: KH_5; pfam13184
1171376009978	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1171376009979	G-X-X-G motif; other site
1171376009980	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1171376009981	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1171376009982	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1171376009983	Sm and related proteins; Region: Sm_like; cl00259
1171376009984	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1171376009985	putative oligomer interface [polypeptide binding]; other site
1171376009986	putative RNA binding site [nucleotide binding]; other site
1171376009987	argininosuccinate synthase; Validated; Region: PRK05370
1171376009988	argininosuccinate synthase; Provisional; Region: PRK13820
1171376009989	Domain of unknown function (DUF1963); Region: DUF1963; cl01600
1171376009990	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1171376009991	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1171376009992	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1171376009993	active site
1171376009994	substrate binding site [chemical binding]; other site
1171376009995	metal binding site [ion binding]; metal-binding site
1171376009996	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1171376009997	dihydropteroate synthase; Region: DHPS; TIGR01496
1171376009998	substrate binding pocket [chemical binding]; other site
1171376009999	dimer interface [polypeptide binding]; other site
1171376010000	inhibitor binding site; inhibition site
1171376010001	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1171376010002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376010003	Walker A motif; other site
1171376010004	ATP binding site [chemical binding]; other site
1171376010005	Walker B motif; other site
1171376010006	arginine finger; other site
1171376010007	Peptidase family M41; Region: Peptidase_M41; pfam01434
1171376010008	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1171376010009	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376010010	S-adenosylmethionine binding site [chemical binding]; other site
1171376010011	RNA-binding protein YhbY; Provisional; Region: PRK10343
1171376010012	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1171376010013	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1171376010014	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1171376010015	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1171376010016	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1171376010017	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1171376010018	GTP1/OBG; Region: GTP1_OBG; pfam01018
1171376010019	Obg GTPase; Region: Obg; cd01898
1171376010020	G1 box; other site
1171376010021	GTP/Mg2+ binding site [chemical binding]; other site
1171376010022	Switch I region; other site
1171376010023	G2 box; other site
1171376010024	G3 box; other site
1171376010025	Switch II region; other site
1171376010026	G4 box; other site
1171376010027	G5 box; other site
1171376010028	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1171376010029	EamA-like transporter family; Region: EamA; pfam00892
1171376010030	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1171376010031	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1171376010032	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1171376010033	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1171376010034	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1171376010035	substrate binding pocket [chemical binding]; other site
1171376010036	chain length determination region; other site
1171376010037	substrate-Mg2+ binding site; other site
1171376010038	catalytic residues [active]
1171376010039	aspartate-rich region 1; other site
1171376010040	active site lid residues [active]
1171376010041	aspartate-rich region 2; other site
1171376010042	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1171376010043	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1171376010044	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1171376010045	hinge; other site
1171376010046	active site
1171376010047	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1171376010048	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1171376010049	anti sigma factor interaction site; other site
1171376010050	regulatory phosphorylation site [posttranslational modification]; other site
1171376010051	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1171376010052	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1171376010053	mce related protein; Region: MCE; pfam02470
1171376010054	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1171376010055	conserved hypothetical integral membrane protein; Region: TIGR00056
1171376010056	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1171376010057	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1171376010058	Walker A/P-loop; other site
1171376010059	ATP binding site [chemical binding]; other site
1171376010060	Q-loop/lid; other site
1171376010061	ABC transporter signature motif; other site
1171376010062	Walker B; other site
1171376010063	D-loop; other site
1171376010064	H-loop/switch region; other site
1171376010065	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1171376010066	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1171376010067	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1171376010068	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1171376010069	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1171376010070	putative active site [active]
1171376010071	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1171376010072	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1171376010073	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1171376010074	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1171376010075	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1171376010076	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1171376010077	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1171376010078	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1171376010079	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1171376010080	Walker A/P-loop; other site
1171376010081	ATP binding site [chemical binding]; other site
1171376010082	Q-loop/lid; other site
1171376010083	ABC transporter signature motif; other site
1171376010084	Walker B; other site
1171376010085	D-loop; other site
1171376010086	H-loop/switch region; other site
1171376010087	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1171376010088	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1171376010089	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1171376010090	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1171376010091	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1171376010092	30S subunit binding site; other site
1171376010093	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376010094	active site
1171376010095	phosphorylation site [posttranslational modification]
1171376010096	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
1171376010097	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1171376010098	dimerization domain swap beta strand [polypeptide binding]; other site
1171376010099	regulatory protein interface [polypeptide binding]; other site
1171376010100	active site
1171376010101	regulatory phosphorylation site [posttranslational modification]; other site
1171376010102	hypothetical protein; Provisional; Region: PRK10345
1171376010103	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1171376010104	Transglycosylase; Region: Transgly; cl17702
1171376010105	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1171376010106	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1171376010107	conserved cys residue [active]
1171376010108	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1171376010109	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1171376010110	putative active site [active]
1171376010111	heme pocket [chemical binding]; other site
1171376010112	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376010113	dimer interface [polypeptide binding]; other site
1171376010114	phosphorylation site [posttranslational modification]
1171376010115	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376010116	ATP binding site [chemical binding]; other site
1171376010117	Mg2+ binding site [ion binding]; other site
1171376010118	G-X-G motif; other site
1171376010119	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376010120	active site
1171376010121	phosphorylation site [posttranslational modification]
1171376010122	intermolecular recognition site; other site
1171376010123	dimerization interface [polypeptide binding]; other site
1171376010124	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1171376010125	putative binding surface; other site
1171376010126	active site
1171376010127	radical SAM protein, TIGR01212 family; Region: TIGR01212
1171376010128	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376010129	FeS/SAM binding site; other site
1171376010130	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1171376010131	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1171376010132	active site
1171376010133	dimer interface [polypeptide binding]; other site
1171376010134	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1171376010135	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1171376010136	active site
1171376010137	FMN binding site [chemical binding]; other site
1171376010138	substrate binding site [chemical binding]; other site
1171376010139	3Fe-4S cluster binding site [ion binding]; other site
1171376010140	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1171376010141	domain interface; other site
1171376010142	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1171376010143	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1171376010144	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376010145	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1171376010146	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1171376010147	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1171376010148	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1171376010149	Na binding site [ion binding]; other site
1171376010150	putative substrate binding site [chemical binding]; other site
1171376010151	cytosine deaminase; Provisional; Region: PRK09230
1171376010152	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1171376010153	active site
1171376010154	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1171376010155	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1171376010156	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1171376010157	nucleotide binding site [chemical binding]; other site
1171376010158	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1171376010159	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1171376010160	putative active site cavity [active]
1171376010161	putative sialic acid transporter; Provisional; Region: PRK03893
1171376010162	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376010163	putative substrate translocation pore; other site
1171376010164	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1171376010165	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1171376010166	inhibitor site; inhibition site
1171376010167	active site
1171376010168	dimer interface [polypeptide binding]; other site
1171376010169	catalytic residue [active]
1171376010170	transcriptional regulator NanR; Provisional; Region: PRK03837
1171376010171	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376010172	DNA-binding site [nucleotide binding]; DNA binding site
1171376010173	FCD domain; Region: FCD; pfam07729
1171376010174	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
1171376010175	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1171376010176	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1171376010177	C-terminal domain interface [polypeptide binding]; other site
1171376010178	putative GSH binding site (G-site) [chemical binding]; other site
1171376010179	dimer interface [polypeptide binding]; other site
1171376010180	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1171376010181	dimer interface [polypeptide binding]; other site
1171376010182	N-terminal domain interface [polypeptide binding]; other site
1171376010183	Family of unknown function (DUF695); Region: DUF695; pfam05117
1171376010184	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
1171376010185	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1171376010186	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1171376010187	23S rRNA interface [nucleotide binding]; other site
1171376010188	L3 interface [polypeptide binding]; other site
1171376010189	Predicted ATPase [General function prediction only]; Region: COG1485
1171376010190	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1171376010191	hypothetical protein; Provisional; Region: PRK11677
1171376010192	serine endoprotease; Provisional; Region: PRK10139
1171376010193	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1171376010194	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1171376010195	protein binding site [polypeptide binding]; other site
1171376010196	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1171376010197	serine endoprotease; Provisional; Region: PRK10898
1171376010198	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1171376010199	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1171376010200	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1171376010201	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1171376010202	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1171376010203	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
1171376010204	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
1171376010205	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1171376010206	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1171376010207	transmembrane helices; other site
1171376010208	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1171376010209	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376010210	DNA-binding site [nucleotide binding]; DNA binding site
1171376010211	FCD domain; Region: FCD; pfam07729
1171376010212	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1171376010213	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376010214	DNA-binding site [nucleotide binding]; DNA binding site
1171376010215	malate dehydrogenase; Provisional; Region: PRK05086
1171376010216	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1171376010217	NAD binding site [chemical binding]; other site
1171376010218	dimerization interface [polypeptide binding]; other site
1171376010219	Substrate binding site [chemical binding]; other site
1171376010220	arginine repressor; Provisional; Region: PRK05066
1171376010221	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1171376010222	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1171376010223	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1171376010224	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1171376010225	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1171376010226	RNAase interaction site [polypeptide binding]; other site
1171376010227	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1171376010228	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1171376010229	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1171376010230	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1171376010231	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376010232	efflux system membrane protein; Provisional; Region: PRK11594
1171376010233	transcriptional regulator; Provisional; Region: PRK10632
1171376010234	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376010235	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1171376010236	putative effector binding pocket; other site
1171376010237	dimerization interface [polypeptide binding]; other site
1171376010238	protease TldD; Provisional; Region: tldD; PRK10735
1171376010239	hypothetical protein; Provisional; Region: PRK10899
1171376010240	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1171376010241	ribonuclease G; Provisional; Region: PRK11712
1171376010242	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1171376010243	homodimer interface [polypeptide binding]; other site
1171376010244	oligonucleotide binding site [chemical binding]; other site
1171376010245	Maf-like protein; Region: Maf; pfam02545
1171376010246	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1171376010247	active site
1171376010248	dimer interface [polypeptide binding]; other site
1171376010249	rod shape-determining protein MreD; Provisional; Region: PRK11060
1171376010250	rod shape-determining protein MreC; Region: mreC; TIGR00219
1171376010251	rod shape-determining protein MreC; Region: MreC; pfam04085
1171376010252	rod shape-determining protein MreB; Provisional; Region: PRK13927
1171376010253	MreB and similar proteins; Region: MreB_like; cd10225
1171376010254	nucleotide binding site [chemical binding]; other site
1171376010255	Mg binding site [ion binding]; other site
1171376010256	putative protofilament interaction site [polypeptide binding]; other site
1171376010257	RodZ interaction site [polypeptide binding]; other site
1171376010258	regulatory protein CsrD; Provisional; Region: PRK11059
1171376010259	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376010260	metal binding site [ion binding]; metal-binding site
1171376010261	active site
1171376010262	I-site; other site
1171376010263	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376010264	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1171376010265	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1171376010266	NADP binding site [chemical binding]; other site
1171376010267	dimer interface [polypeptide binding]; other site
1171376010268	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1171376010269	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1171376010270	Moco binding site; other site
1171376010271	metal coordination site [ion binding]; other site
1171376010272	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1171376010273	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1171376010274	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1171376010275	carboxyltransferase (CT) interaction site; other site
1171376010276	biotinylation site [posttranslational modification]; other site
1171376010277	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1171376010278	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1171376010279	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1171376010280	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1171376010281	hypothetical protein; Provisional; Region: PRK10633
1171376010282	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1171376010283	Na binding site [ion binding]; other site
1171376010284	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
1171376010285	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1171376010286	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1171376010287	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1171376010288	FMN binding site [chemical binding]; other site
1171376010289	active site
1171376010290	catalytic residues [active]
1171376010291	substrate binding site [chemical binding]; other site
1171376010292	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1171376010293	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1171376010294	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1171376010295	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376010296	DNA methylase; Region: N6_N4_Mtase; pfam01555
1171376010297	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
1171376010298	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1171376010299	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1171376010300	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1171376010301	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376010302	metal binding site [ion binding]; metal-binding site
1171376010303	active site
1171376010304	I-site; other site
1171376010305	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376010306	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
1171376010307	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376010308	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1171376010309	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1171376010310	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1171376010311	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376010312	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1171376010313	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1171376010314	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1171376010315	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1171376010316	trimer interface [polypeptide binding]; other site
1171376010317	putative metal binding site [ion binding]; other site
1171376010318	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1171376010319	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1171376010320	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1171376010321	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1171376010322	shikimate binding site; other site
1171376010323	NAD(P) binding site [chemical binding]; other site
1171376010324	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1171376010325	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1171376010326	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1171376010327	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1171376010328	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1171376010329	hypothetical protein; Validated; Region: PRK03430
1171376010330	hypothetical protein; Provisional; Region: PRK10736
1171376010331	DNA protecting protein DprA; Region: dprA; TIGR00732
1171376010332	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1171376010333	active site
1171376010334	catalytic residues [active]
1171376010335	metal binding site [ion binding]; metal-binding site
1171376010336	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1171376010337	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1171376010338	putative active site [active]
1171376010339	substrate binding site [chemical binding]; other site
1171376010340	putative cosubstrate binding site; other site
1171376010341	catalytic site [active]
1171376010342	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1171376010343	substrate binding site [chemical binding]; other site
1171376010344	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1171376010345	putative RNA binding site [nucleotide binding]; other site
1171376010346	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1171376010347	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376010348	S-adenosylmethionine binding site [chemical binding]; other site
1171376010349	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1171376010350	TrkA-N domain; Region: TrkA_N; pfam02254
1171376010351	TrkA-C domain; Region: TrkA_C; pfam02080
1171376010352	TrkA-N domain; Region: TrkA_N; pfam02254
1171376010353	TrkA-C domain; Region: TrkA_C; pfam02080
1171376010354	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1171376010355	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1171376010356	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1171376010357	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1171376010358	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1171376010359	DNA binding residues [nucleotide binding]
1171376010360	dimer interface [polypeptide binding]; other site
1171376010361	metal binding site [ion binding]; metal-binding site
1171376010362	hypothetical protein; Provisional; Region: PRK10203
1171376010363	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1171376010364	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1171376010365	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1171376010366	alphaNTD homodimer interface [polypeptide binding]; other site
1171376010367	alphaNTD - beta interaction site [polypeptide binding]; other site
1171376010368	alphaNTD - beta' interaction site [polypeptide binding]; other site
1171376010369	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1171376010370	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1171376010371	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1171376010372	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1171376010373	RNA binding surface [nucleotide binding]; other site
1171376010374	30S ribosomal protein S11; Validated; Region: PRK05309
1171376010375	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1171376010376	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1171376010377	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1171376010378	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1171376010379	SecY translocase; Region: SecY; pfam00344
1171376010380	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1171376010381	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1171376010382	23S rRNA binding site [nucleotide binding]; other site
1171376010383	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1171376010384	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1171376010385	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1171376010386	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1171376010387	23S rRNA interface [nucleotide binding]; other site
1171376010388	5S rRNA interface [nucleotide binding]; other site
1171376010389	L27 interface [polypeptide binding]; other site
1171376010390	L5 interface [polypeptide binding]; other site
1171376010391	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1171376010392	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1171376010393	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1171376010394	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1171376010395	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1171376010396	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1171376010397	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1171376010398	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1171376010399	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1171376010400	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1171376010401	RNA binding site [nucleotide binding]; other site
1171376010402	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1171376010403	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1171376010404	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1171376010405	23S rRNA interface [nucleotide binding]; other site
1171376010406	putative translocon interaction site; other site
1171376010407	signal recognition particle (SRP54) interaction site; other site
1171376010408	L23 interface [polypeptide binding]; other site
1171376010409	trigger factor interaction site; other site
1171376010410	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1171376010411	23S rRNA interface [nucleotide binding]; other site
1171376010412	5S rRNA interface [nucleotide binding]; other site
1171376010413	putative antibiotic binding site [chemical binding]; other site
1171376010414	L25 interface [polypeptide binding]; other site
1171376010415	L27 interface [polypeptide binding]; other site
1171376010416	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1171376010417	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1171376010418	G-X-X-G motif; other site
1171376010419	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1171376010420	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1171376010421	protein-rRNA interface [nucleotide binding]; other site
1171376010422	putative translocon binding site; other site
1171376010423	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1171376010424	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1171376010425	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1171376010426	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1171376010427	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1171376010428	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1171376010429	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1171376010430	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1171376010431	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1171376010432	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1171376010433	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1171376010434	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1171376010435	heme binding site [chemical binding]; other site
1171376010436	ferroxidase pore; other site
1171376010437	ferroxidase diiron center [ion binding]; other site
1171376010438	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1171376010439	elongation factor Tu; Reviewed; Region: PRK00049
1171376010440	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1171376010441	G1 box; other site
1171376010442	GEF interaction site [polypeptide binding]; other site
1171376010443	GTP/Mg2+ binding site [chemical binding]; other site
1171376010444	Switch I region; other site
1171376010445	G2 box; other site
1171376010446	G3 box; other site
1171376010447	Switch II region; other site
1171376010448	G4 box; other site
1171376010449	G5 box; other site
1171376010450	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1171376010451	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1171376010452	Antibiotic Binding Site [chemical binding]; other site
1171376010453	elongation factor G; Reviewed; Region: PRK00007
1171376010454	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1171376010455	G1 box; other site
1171376010456	putative GEF interaction site [polypeptide binding]; other site
1171376010457	GTP/Mg2+ binding site [chemical binding]; other site
1171376010458	Switch I region; other site
1171376010459	G2 box; other site
1171376010460	G3 box; other site
1171376010461	Switch II region; other site
1171376010462	G4 box; other site
1171376010463	G5 box; other site
1171376010464	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1171376010465	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1171376010466	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1171376010467	30S ribosomal protein S7; Validated; Region: PRK05302
1171376010468	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1171376010469	sulfur relay protein TusC; Validated; Region: PRK00211
1171376010470	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1171376010471	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1171376010472	YheO-like PAS domain; Region: PAS_6; pfam08348
1171376010473	HTH domain; Region: HTH_22; pfam13309
1171376010474	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1171376010475	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1171376010476	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1171376010477	phi X174 lysis protein; Provisional; Region: PRK02793
1171376010478	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1171376010479	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1171376010480	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1171376010481	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1171376010482	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1171376010483	TrkA-N domain; Region: TrkA_N; pfam02254
1171376010484	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1171376010485	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1171376010486	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376010487	Walker A/P-loop; other site
1171376010488	ATP binding site [chemical binding]; other site
1171376010489	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1171376010490	ABC transporter signature motif; other site
1171376010491	Walker B; other site
1171376010492	D-loop; other site
1171376010493	ABC transporter; Region: ABC_tran_2; pfam12848
1171376010494	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1171376010495	putative monooxygenase; Provisional; Region: PRK11118
1171376010496	putative hydrolase; Provisional; Region: PRK10985
1171376010497	hypothetical protein; Provisional; Region: PRK04966
1171376010498	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1171376010499	active site
1171376010500	hypothetical protein; Provisional; Region: PRK10738
1171376010501	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1171376010502	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1171376010503	ligand binding site [chemical binding]; other site
1171376010504	flexible hinge region; other site
1171376010505	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1171376010506	putative switch regulator; other site
1171376010507	non-specific DNA interactions [nucleotide binding]; other site
1171376010508	DNA binding site [nucleotide binding]
1171376010509	sequence specific DNA binding site [nucleotide binding]; other site
1171376010510	putative cAMP binding site [chemical binding]; other site
1171376010511	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1171376010512	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1171376010513	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1171376010514	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1171376010515	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1171376010516	inhibitor-cofactor binding pocket; inhibition site
1171376010517	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376010518	catalytic residue [active]
1171376010519	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1171376010520	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1171376010521	glutamine binding [chemical binding]; other site
1171376010522	catalytic triad [active]
1171376010523	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1171376010524	cell filamentation protein Fic; Provisional; Region: PRK10347
1171376010525	hypothetical protein; Provisional; Region: PRK10204
1171376010526	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1171376010527	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1171376010528	substrate binding site [chemical binding]; other site
1171376010529	putative transporter; Provisional; Region: PRK03699
1171376010530	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376010531	putative substrate translocation pore; other site
1171376010532	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1171376010533	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376010534	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1171376010535	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1171376010536	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1171376010537	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1171376010538	nitrite transporter NirC; Provisional; Region: PRK11562
1171376010539	siroheme synthase; Provisional; Region: cysG; PRK10637
1171376010540	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1171376010541	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1171376010542	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1171376010543	active site
1171376010544	SAM binding site [chemical binding]; other site
1171376010545	homodimer interface [polypeptide binding]; other site
1171376010546	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1171376010547	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1171376010548	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1171376010549	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1171376010550	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1171376010551	active site
1171376010552	HIGH motif; other site
1171376010553	dimer interface [polypeptide binding]; other site
1171376010554	KMSKS motif; other site
1171376010555	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1171376010556	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376010557	motif II; other site
1171376010558	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1171376010559	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1171376010560	substrate binding site [chemical binding]; other site
1171376010561	hexamer interface [polypeptide binding]; other site
1171376010562	metal binding site [ion binding]; metal-binding site
1171376010563	DNA adenine methylase; Provisional; Region: PRK10904
1171376010564	cell division protein DamX; Validated; Region: PRK10905
1171376010565	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
1171376010566	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1171376010567	active site
1171376010568	dimer interface [polypeptide binding]; other site
1171376010569	metal binding site [ion binding]; metal-binding site
1171376010570	shikimate kinase; Reviewed; Region: aroK; PRK00131
1171376010571	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1171376010572	ADP binding site [chemical binding]; other site
1171376010573	magnesium binding site [ion binding]; other site
1171376010574	putative shikimate binding site; other site
1171376010575	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1171376010576	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1171376010577	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
1171376010578	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1171376010579	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1171376010580	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1171376010581	Transglycosylase; Region: Transgly; pfam00912
1171376010582	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1171376010583	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1171376010584	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1171376010585	ADP-ribose binding site [chemical binding]; other site
1171376010586	dimer interface [polypeptide binding]; other site
1171376010587	active site
1171376010588	nudix motif; other site
1171376010589	metal binding site [ion binding]; metal-binding site
1171376010590	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1171376010591	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1171376010592	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376010593	motif II; other site
1171376010594	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1171376010595	RNA binding surface [nucleotide binding]; other site
1171376010596	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1171376010597	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1171376010598	dimerization interface [polypeptide binding]; other site
1171376010599	domain crossover interface; other site
1171376010600	redox-dependent activation switch; other site
1171376010601	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1171376010602	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1171376010603	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1171376010604	active site
1171376010605	substrate-binding site [chemical binding]; other site
1171376010606	metal-binding site [ion binding]
1171376010607	ATP binding site [chemical binding]; other site
1171376010608	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1171376010609	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376010610	dimerization interface [polypeptide binding]; other site
1171376010611	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376010612	dimer interface [polypeptide binding]; other site
1171376010613	phosphorylation site [posttranslational modification]
1171376010614	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376010615	ATP binding site [chemical binding]; other site
1171376010616	G-X-G motif; other site
1171376010617	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1171376010618	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376010619	active site
1171376010620	phosphorylation site [posttranslational modification]
1171376010621	intermolecular recognition site; other site
1171376010622	dimerization interface [polypeptide binding]; other site
1171376010623	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376010624	DNA binding site [nucleotide binding]
1171376010625	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1171376010626	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1171376010627	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1171376010628	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1171376010629	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1171376010630	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1171376010631	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1171376010632	RNA binding site [nucleotide binding]; other site
1171376010633	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1171376010634	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1171376010635	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1171376010636	G1 box; other site
1171376010637	GTP/Mg2+ binding site [chemical binding]; other site
1171376010638	Switch I region; other site
1171376010639	G2 box; other site
1171376010640	G3 box; other site
1171376010641	Switch II region; other site
1171376010642	G4 box; other site
1171376010643	G5 box; other site
1171376010644	Nucleoside recognition; Region: Gate; pfam07670
1171376010645	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1171376010646	Nucleoside recognition; Region: Gate; pfam07670
1171376010647	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1171376010648	hypothetical protein; Provisional; Region: PRK09956
1171376010649	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1171376010650	carboxylesterase BioH; Provisional; Region: PRK10349
1171376010651	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1171376010652	DNA utilization protein GntX; Provisional; Region: PRK11595
1171376010653	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1171376010654	active site
1171376010655	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1171376010656	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1171376010657	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1171376010658	high-affinity gluconate transporter; Provisional; Region: PRK14984
1171376010659	gluconate transporter; Region: gntP; TIGR00791
1171376010660	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1171376010661	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1171376010662	maltodextrin phosphorylase; Provisional; Region: PRK14985
1171376010663	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1171376010664	homodimer interface [polypeptide binding]; other site
1171376010665	active site pocket [active]
1171376010666	transcriptional regulator MalT; Provisional; Region: PRK04841
1171376010667	AAA ATPase domain; Region: AAA_16; pfam13191
1171376010668	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376010669	DNA binding residues [nucleotide binding]
1171376010670	dimerization interface [polypeptide binding]; other site
1171376010671	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
1171376010672	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
1171376010673	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
1171376010674	RNA 3' phosphate cyclase domain (class II). These proteins function as RNA cyclase to catalyze the ATP-dependent conversion of 3'-phosphate to a 2'.3'-cyclic phosphodiester at the end of RNA molecule. A conserved catalytic histidine...; Region: RNA_Cyclase_Class_II; cd00874
1171376010675	putative active site [active]
1171376010676	adenylation catalytic residue [active]
1171376010677	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1171376010678	hypothetical protein; Reviewed; Region: PRK09588
1171376010679	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
1171376010680	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
1171376010681	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376010682	Walker A motif; other site
1171376010683	ATP binding site [chemical binding]; other site
1171376010684	Walker B motif; other site
1171376010685	arginine finger; other site
1171376010686	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1171376010687	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1171376010688	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376010689	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1171376010690	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1171376010691	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1171376010692	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1171376010693	active site residue [active]
1171376010694	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1171376010695	hypothetical protein; Provisional; Region: PRK09781
1171376010696	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
1171376010697	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1171376010698	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1171376010699	dimer interface [polypeptide binding]; other site
1171376010700	active site
1171376010701	metal binding site [ion binding]; metal-binding site
1171376010702	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376010703	D-galactonate transporter; Region: 2A0114; TIGR00893
1171376010704	putative substrate translocation pore; other site
1171376010705	Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism / Carbohydrate transport and metabolism]; Region: IlvD; COG0129
1171376010706	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1171376010707	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1171376010708	inhibitor site; inhibition site
1171376010709	active site
1171376010710	dimer interface [polypeptide binding]; other site
1171376010711	catalytic residue [active]
1171376010712	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1171376010713	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1171376010714	Bacterial transcriptional regulator; Region: IclR; pfam01614
1171376010715	glycogen phosphorylase; Provisional; Region: PRK14986
1171376010716	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1171376010717	homodimer interface [polypeptide binding]; other site
1171376010718	active site pocket [active]
1171376010719	glycogen synthase; Provisional; Region: glgA; PRK00654
1171376010720	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1171376010721	ADP-binding pocket [chemical binding]; other site
1171376010722	homodimer interface [polypeptide binding]; other site
1171376010723	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1171376010724	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1171376010725	ligand binding site; other site
1171376010726	oligomer interface; other site
1171376010727	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1171376010728	dimer interface [polypeptide binding]; other site
1171376010729	N-terminal domain interface [polypeptide binding]; other site
1171376010730	sulfate 1 binding site; other site
1171376010731	glycogen debranching enzyme; Provisional; Region: PRK03705
1171376010732	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1171376010733	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1171376010734	active site
1171376010735	catalytic site [active]
1171376010736	glycogen branching enzyme; Provisional; Region: PRK05402
1171376010737	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1171376010738	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1171376010739	active site
1171376010740	catalytic site [active]
1171376010741	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1171376010742	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1171376010743	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1171376010744	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
1171376010745	low affinity gluconate transporter; Provisional; Region: PRK10472
1171376010746	gluconate transporter; Region: gntP; TIGR00791
1171376010747	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1171376010748	ATP-binding site [chemical binding]; other site
1171376010749	Gluconate-6-phosphate binding site [chemical binding]; other site
1171376010750	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1171376010751	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376010752	DNA binding site [nucleotide binding]
1171376010753	domain linker motif; other site
1171376010754	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1171376010755	putative ligand binding site [chemical binding]; other site
1171376010756	putative dimerization interface [polypeptide binding]; other site
1171376010757	Pirin-related protein [General function prediction only]; Region: COG1741
1171376010758	Pirin; Region: Pirin; pfam02678
1171376010759	putative oxidoreductase; Provisional; Region: PRK10206
1171376010760	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1171376010761	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1171376010762	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1171376010763	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376010764	Coenzyme A binding pocket [chemical binding]; other site
1171376010765	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1171376010766	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1171376010767	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376010768	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1171376010769	substrate binding site [chemical binding]; other site
1171376010770	dimer interface [polypeptide binding]; other site
1171376010771	ATP binding site [chemical binding]; other site
1171376010772	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1171376010773	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1171376010774	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1171376010775	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1171376010776	active site
1171376010777	substrate binding pocket [chemical binding]; other site
1171376010778	homodimer interaction site [polypeptide binding]; other site
1171376010779	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1171376010780	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1171376010781	hypothetical protein; Provisional; Region: PRK10350
1171376010782	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1171376010783	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1171376010784	putative active site [active]
1171376010785	catalytic site [active]
1171376010786	putative metal binding site [ion binding]; other site
1171376010787	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1171376010788	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1171376010789	Walker A/P-loop; other site
1171376010790	ATP binding site [chemical binding]; other site
1171376010791	Q-loop/lid; other site
1171376010792	ABC transporter signature motif; other site
1171376010793	Walker B; other site
1171376010794	D-loop; other site
1171376010795	H-loop/switch region; other site
1171376010796	TOBE domain; Region: TOBE_2; pfam08402
1171376010797	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1171376010798	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376010799	dimer interface [polypeptide binding]; other site
1171376010800	conserved gate region; other site
1171376010801	ABC-ATPase subunit interface; other site
1171376010802	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1171376010803	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376010804	dimer interface [polypeptide binding]; other site
1171376010805	conserved gate region; other site
1171376010806	putative PBP binding loops; other site
1171376010807	ABC-ATPase subunit interface; other site
1171376010808	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1171376010809	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1171376010810	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
1171376010811	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1171376010812	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1171376010813	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1171376010814	Walker A/P-loop; other site
1171376010815	ATP binding site [chemical binding]; other site
1171376010816	Q-loop/lid; other site
1171376010817	ABC transporter signature motif; other site
1171376010818	Walker B; other site
1171376010819	D-loop; other site
1171376010820	H-loop/switch region; other site
1171376010821	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1171376010822	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1171376010823	Walker A/P-loop; other site
1171376010824	ATP binding site [chemical binding]; other site
1171376010825	Q-loop/lid; other site
1171376010826	ABC transporter signature motif; other site
1171376010827	Walker B; other site
1171376010828	D-loop; other site
1171376010829	H-loop/switch region; other site
1171376010830	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1171376010831	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1171376010832	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1171376010833	TM-ABC transporter signature motif; other site
1171376010834	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1171376010835	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1171376010836	TM-ABC transporter signature motif; other site
1171376010837	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1171376010838	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1171376010839	dimerization interface [polypeptide binding]; other site
1171376010840	ligand binding site [chemical binding]; other site
1171376010841	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1171376010842	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1171376010843	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1171376010844	dimerization interface [polypeptide binding]; other site
1171376010845	ligand binding site [chemical binding]; other site
1171376010846	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1171376010847	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1171376010848	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1171376010849	DNA binding residues [nucleotide binding]
1171376010850	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1171376010851	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1171376010852	cell division protein FtsE; Provisional; Region: PRK10908
1171376010853	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376010854	Walker A/P-loop; other site
1171376010855	ATP binding site [chemical binding]; other site
1171376010856	Q-loop/lid; other site
1171376010857	ABC transporter signature motif; other site
1171376010858	Walker B; other site
1171376010859	D-loop; other site
1171376010860	H-loop/switch region; other site
1171376010861	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1171376010862	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1171376010863	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1171376010864	P loop; other site
1171376010865	GTP binding site [chemical binding]; other site
1171376010866	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1171376010867	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376010868	S-adenosylmethionine binding site [chemical binding]; other site
1171376010869	hypothetical protein; Provisional; Region: PRK10910
1171376010870	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1171376010871	Predicted membrane protein [Function unknown]; Region: COG3714
1171376010872	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1171376010873	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1171376010874	metal-binding site [ion binding]
1171376010875	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1171376010876	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1171376010877	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1171376010878	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1171376010879	dimer interface [polypeptide binding]; other site
1171376010880	ligand binding site [chemical binding]; other site
1171376010881	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376010882	dimerization interface [polypeptide binding]; other site
1171376010883	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1171376010884	dimer interface [polypeptide binding]; other site
1171376010885	putative CheW interface [polypeptide binding]; other site
1171376010886	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1171376010887	CPxP  motif; other site
1171376010888	hypothetical protein; Provisional; Region: PRK11212
1171376010889	hypothetical protein; Provisional; Region: PRK11615
1171376010890	major facilitator superfamily transporter; Provisional; Region: PRK05122
1171376010891	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376010892	putative substrate translocation pore; other site
1171376010893	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1171376010894	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1171376010895	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1171376010896	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1171376010897	nickel responsive regulator; Provisional; Region: PRK02967
1171376010898	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1171376010899	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1171376010900	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1171376010901	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1171376010902	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1171376010903	Walker A/P-loop; other site
1171376010904	ATP binding site [chemical binding]; other site
1171376010905	Q-loop/lid; other site
1171376010906	ABC transporter signature motif; other site
1171376010907	Walker B; other site
1171376010908	D-loop; other site
1171376010909	H-loop/switch region; other site
1171376010910	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1171376010911	Walker A/P-loop; other site
1171376010912	ATP binding site [chemical binding]; other site
1171376010913	Q-loop/lid; other site
1171376010914	ABC transporter signature motif; other site
1171376010915	Walker B; other site
1171376010916	D-loop; other site
1171376010917	H-loop/switch region; other site
1171376010918	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1171376010919	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1171376010920	HlyD family secretion protein; Region: HlyD; pfam00529
1171376010921	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1171376010922	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376010923	Predicted flavoproteins [General function prediction only]; Region: COG2081
1171376010924	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1171376010925	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1171376010926	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1171376010927	universal stress protein UspB; Provisional; Region: PRK04960
1171376010928	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1171376010929	Ligand Binding Site [chemical binding]; other site
1171376010930	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1171376010931	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376010932	putative substrate translocation pore; other site
1171376010933	POT family; Region: PTR2; pfam00854
1171376010934	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376010935	S-adenosylmethionine binding site [chemical binding]; other site
1171376010936	oligopeptidase A; Provisional; Region: PRK10911
1171376010937	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1171376010938	active site
1171376010939	Zn binding site [ion binding]; other site
1171376010940	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1171376010941	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1171376010942	active site
1171376010943	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1171376010944	glutathione reductase; Validated; Region: PRK06116
1171376010945	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1171376010946	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376010947	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1171376010948	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1171376010949	active site
1171376010950	homodimer interface [polypeptide binding]; other site
1171376010951	homotetramer interface [polypeptide binding]; other site
1171376010952	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1171376010953	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1171376010954	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
1171376010955	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376010956	substrate binding site [chemical binding]; other site
1171376010957	ATP binding site [chemical binding]; other site
1171376010958	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1171376010959	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1171376010960	putative active site [active]
1171376010961	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1171376010962	dimer interface [polypeptide binding]; other site
1171376010963	active site
1171376010964	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1171376010965	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376010966	DNA-binding site [nucleotide binding]; DNA binding site
1171376010967	UTRA domain; Region: UTRA; pfam07702
1171376010968	trehalase; Provisional; Region: treF; PRK13270
1171376010969	Trehalase; Region: Trehalase; pfam01204
1171376010970	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
1171376010971	catalytic residue [active]
1171376010972	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1171376010973	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376010974	DNA binding residues [nucleotide binding]
1171376010975	dimerization interface [polypeptide binding]; other site
1171376010976	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376010977	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376010978	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1171376010979	putative effector binding pocket; other site
1171376010980	putative dimerization interface [polypeptide binding]; other site
1171376010981	inner membrane protein YhjD; Region: TIGR00766
1171376010982	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376010983	metabolite-proton symporter; Region: 2A0106; TIGR00883
1171376010984	putative substrate translocation pore; other site
1171376010985	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1171376010986	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1171376010987	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376010988	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376010989	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1171376010990	substrate binding site [chemical binding]; other site
1171376010991	ATP binding site [chemical binding]; other site
1171376010992	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1171376010993	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1171376010994	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1171376010995	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1171376010996	putative diguanylate cyclase; Provisional; Region: PRK13561
1171376010997	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376010998	metal binding site [ion binding]; metal-binding site
1171376010999	active site
1171376011000	I-site; other site
1171376011001	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376011002	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1171376011003	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1171376011004	TPR motif; other site
1171376011005	binding surface
1171376011006	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1171376011007	TPR motif; other site
1171376011008	binding surface
1171376011009	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1171376011010	binding surface
1171376011011	TPR motif; other site
1171376011012	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1171376011013	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1171376011014	cellulose synthase regulator protein; Provisional; Region: PRK11114
1171376011015	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1171376011016	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1171376011017	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1171376011018	DXD motif; other site
1171376011019	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1171376011020	PilZ domain; Region: PilZ; pfam07238
1171376011021	cell division protein; Provisional; Region: PRK10037
1171376011022	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1171376011023	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
1171376011024	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
1171376011025	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
1171376011026	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
1171376011027	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1171376011028	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1171376011029	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1171376011030	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1171376011031	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1171376011032	dipeptide transporter; Provisional; Region: PRK10913
1171376011033	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1171376011034	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376011035	dimer interface [polypeptide binding]; other site
1171376011036	conserved gate region; other site
1171376011037	putative PBP binding loops; other site
1171376011038	ABC-ATPase subunit interface; other site
1171376011039	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1171376011040	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376011041	dimer interface [polypeptide binding]; other site
1171376011042	conserved gate region; other site
1171376011043	putative PBP binding loops; other site
1171376011044	ABC-ATPase subunit interface; other site
1171376011045	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1171376011046	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1171376011047	peptide binding site [polypeptide binding]; other site
1171376011048	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1171376011049	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
1171376011050	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1171376011051	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376011052	DNA binding site [nucleotide binding]
1171376011053	domain linker motif; other site
1171376011054	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
1171376011055	putative dimerization interface [polypeptide binding]; other site
1171376011056	putative ligand binding site [chemical binding]; other site
1171376011057	phosphoethanolamine transferase; Provisional; Region: PRK11560
1171376011058	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1171376011059	Sulfatase; Region: Sulfatase; pfam00884
1171376011060	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
1171376011061	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
1171376011062	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
1171376011063	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376011064	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376011065	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376011066	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
1171376011067	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376011068	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376011069	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
1171376011070	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1171376011071	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
1171376011072	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376011073	Coenzyme A binding pocket [chemical binding]; other site
1171376011074	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1171376011075	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1171376011076	molybdopterin cofactor binding site [chemical binding]; other site
1171376011077	substrate binding site [chemical binding]; other site
1171376011078	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1171376011079	molybdopterin cofactor binding site; other site
1171376011080	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1171376011081	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1171376011082	ligand binding site [chemical binding]; other site
1171376011083	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1171376011084	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1171376011085	dimerization interface [polypeptide binding]; other site
1171376011086	ligand binding site [chemical binding]; other site
1171376011087	NADP binding site [chemical binding]; other site
1171376011088	catalytic site [active]
1171376011089	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1171376011090	Predicted transcriptional regulator [Transcription]; Region: COG2944
1171376011091	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376011092	salt bridge; other site
1171376011093	non-specific DNA binding site [nucleotide binding]; other site
1171376011094	sequence-specific DNA binding site [nucleotide binding]; other site
1171376011095	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1171376011096	DNA-binding site [nucleotide binding]; DNA binding site
1171376011097	RNA-binding motif; other site
1171376011098	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1171376011099	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1171376011100	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1171376011101	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376011102	Coenzyme A binding pocket [chemical binding]; other site
1171376011103	Integrase core domain; Region: rve; pfam00665
1171376011104	Integrase core domain; Region: rve_2; pfam13333
1171376011105	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1171376011106	DALR anticodon binding domain; Region: DALR_1; pfam05746
1171376011107	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1171376011108	dimer interface [polypeptide binding]; other site
1171376011109	motif 1; other site
1171376011110	active site
1171376011111	motif 2; other site
1171376011112	motif 3; other site
1171376011113	YsaB-like lipoprotein; Region: YsaB; pfam13983
1171376011114	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1171376011115	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1171376011116	Predicted membrane protein [Function unknown]; Region: COG4682
1171376011117	yiaA/B two helix domain; Region: YiaAB; cl01759
1171376011118	yiaA/B two helix domain; Region: YiaAB; cl01759
1171376011119	xylulokinase; Provisional; Region: PRK15027
1171376011120	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1171376011121	N- and C-terminal domain interface [polypeptide binding]; other site
1171376011122	active site
1171376011123	MgATP binding site [chemical binding]; other site
1171376011124	catalytic site [active]
1171376011125	metal binding site [ion binding]; metal-binding site
1171376011126	xylulose binding site [chemical binding]; other site
1171376011127	homodimer interface [polypeptide binding]; other site
1171376011128	xylose isomerase; Provisional; Region: PRK05474
1171376011129	xylose isomerase; Region: xylose_isom_A; TIGR02630
1171376011130	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1171376011131	putative dimerization interface [polypeptide binding]; other site
1171376011132	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1171376011133	putative ligand binding site [chemical binding]; other site
1171376011134	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376011135	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1171376011136	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376011137	hypothetical protein; Provisional; Region: PRK10356
1171376011138	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1171376011139	alpha-amylase; Reviewed; Region: malS; PRK09505
1171376011140	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1171376011141	active site
1171376011142	catalytic site [active]
1171376011143	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1171376011144	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376011145	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376011146	homodimer interface [polypeptide binding]; other site
1171376011147	catalytic residue [active]
1171376011148	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1171376011149	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1171376011150	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1171376011151	Bacterial transcriptional regulator; Region: IclR; pfam01614
1171376011152	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1171376011153	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1171376011154	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
1171376011155	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
1171376011156	DctM-like transporters; Region: DctM; pfam06808
1171376011157	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1171376011158	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1171376011159	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1171376011160	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1171376011161	putative N- and C-terminal domain interface [polypeptide binding]; other site
1171376011162	putative active site [active]
1171376011163	MgATP binding site [chemical binding]; other site
1171376011164	catalytic site [active]
1171376011165	metal binding site [ion binding]; metal-binding site
1171376011166	putative xylulose binding site [chemical binding]; other site
1171376011167	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1171376011168	active site
1171376011169	dimer interface [polypeptide binding]; other site
1171376011170	magnesium binding site [ion binding]; other site
1171376011171	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1171376011172	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1171376011173	AP (apurinic/apyrimidinic) site pocket; other site
1171376011174	DNA interaction; other site
1171376011175	Metal-binding active site; metal-binding site
1171376011176	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1171376011177	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1171376011178	intersubunit interface [polypeptide binding]; other site
1171376011179	active site
1171376011180	Zn2+ binding site [ion binding]; other site
1171376011181	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1171376011182	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1171376011183	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376011184	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1171376011185	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1171376011186	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1171376011187	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1171376011188	NAD(P) binding site [chemical binding]; other site
1171376011189	catalytic residues [active]
1171376011190	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1171376011191	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1171376011192	nucleotide binding site [chemical binding]; other site
1171376011193	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1171376011194	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1171376011195	G1 box; other site
1171376011196	putative GEF interaction site [polypeptide binding]; other site
1171376011197	GTP/Mg2+ binding site [chemical binding]; other site
1171376011198	Switch I region; other site
1171376011199	G2 box; other site
1171376011200	G3 box; other site
1171376011201	Switch II region; other site
1171376011202	G4 box; other site
1171376011203	G5 box; other site
1171376011204	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1171376011205	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1171376011206	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1171376011207	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1171376011208	selenocysteine synthase; Provisional; Region: PRK04311
1171376011209	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1171376011210	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1171376011211	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1171376011212	catalytic residue [active]
1171376011213	putative glutathione S-transferase; Provisional; Region: PRK10357
1171376011214	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1171376011215	putative C-terminal domain interface [polypeptide binding]; other site
1171376011216	putative GSH binding site (G-site) [chemical binding]; other site
1171376011217	putative dimer interface [polypeptide binding]; other site
1171376011218	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1171376011219	dimer interface [polypeptide binding]; other site
1171376011220	N-terminal domain interface [polypeptide binding]; other site
1171376011221	putative substrate binding pocket (H-site) [chemical binding]; other site
1171376011222	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1171376011223	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1171376011224	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1171376011225	active site
1171376011226	P-loop; other site
1171376011227	phosphorylation site [posttranslational modification]
1171376011228	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376011229	active site
1171376011230	phosphorylation site [posttranslational modification]
1171376011231	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1171376011232	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1171376011233	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1171376011234	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1171376011235	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1171376011236	hypothetical protein; Provisional; Region: PRK11020
1171376011237	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
1171376011238	potential frameshift: common BLAST hit: gi|383498325|ref|YP_005399014.1| inner membrane protein
1171376011239	L-lactate permease; Provisional; Region: PRK10420
1171376011240	glycolate transporter; Provisional; Region: PRK09695
1171376011241	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1171376011242	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376011243	DNA-binding site [nucleotide binding]; DNA binding site
1171376011244	FCD domain; Region: FCD; pfam07729
1171376011245	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1171376011246	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1171376011247	active site
1171376011248	substrate binding site [chemical binding]; other site
1171376011249	FMN binding site [chemical binding]; other site
1171376011250	putative catalytic residues [active]
1171376011251	putative rRNA methylase; Provisional; Region: PRK10358
1171376011252	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1171376011253	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376011254	DNA binding site [nucleotide binding]
1171376011255	domain linker motif; other site
1171376011256	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1171376011257	putative dimerization interface [polypeptide binding]; other site
1171376011258	putative ligand binding site [chemical binding]; other site
1171376011259	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1171376011260	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1171376011261	active site pocket [active]
1171376011262	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011263	D-galactonate transporter; Region: 2A0114; TIGR00893
1171376011264	putative substrate translocation pore; other site
1171376011265	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1171376011266	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1171376011267	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1171376011268	trimer interface [polypeptide binding]; other site
1171376011269	active site
1171376011270	substrate binding site [chemical binding]; other site
1171376011271	CoA binding site [chemical binding]; other site
1171376011272	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1171376011273	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1171376011274	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1171376011275	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1171376011276	SecA binding site; other site
1171376011277	Preprotein binding site; other site
1171376011278	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1171376011279	GSH binding site [chemical binding]; other site
1171376011280	catalytic residues [active]
1171376011281	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1171376011282	active site residue [active]
1171376011283	phosphoglyceromutase; Provisional; Region: PRK05434
1171376011284	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1171376011285	AmiB activator; Provisional; Region: PRK11637
1171376011286	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1171376011287	Peptidase family M23; Region: Peptidase_M23; pfam01551
1171376011288	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1171376011289	NodB motif; other site
1171376011290	putative active site [active]
1171376011291	putative catalytic site [active]
1171376011292	Zn binding site [ion binding]; other site
1171376011293	putative glycosyl transferase; Provisional; Region: PRK10073
1171376011294	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1171376011295	active site
1171376011296	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1171376011297	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1171376011298	NAD(P) binding site [chemical binding]; other site
1171376011299	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1171376011300	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1171376011301	substrate-cofactor binding pocket; other site
1171376011302	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376011303	catalytic residue [active]
1171376011304	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1171376011305	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1171376011306	NADP binding site [chemical binding]; other site
1171376011307	homopentamer interface [polypeptide binding]; other site
1171376011308	substrate binding site [chemical binding]; other site
1171376011309	active site
1171376011310	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1171376011311	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1171376011312	putative active site [active]
1171376011313	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1171376011314	Glycosyltransferase family 9 (heptosyltransferase); Region: Glyco_transf_9; pfam01075
1171376011315	putative active site [active]
1171376011316	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1171376011317	O-antigen ligase RfaL; Provisional; Region: PRK15487
1171376011318	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
1171376011319	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1171376011320	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
1171376011321	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
1171376011322	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1171376011323	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1171376011324	Ligand binding site; other site
1171376011325	metal-binding site
1171376011326	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1171376011327	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1171376011328	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1171376011329	Ligand binding site; other site
1171376011330	metal-binding site
1171376011331	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1171376011332	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
1171376011333	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1171376011334	putative ADP-binding pocket [chemical binding]; other site
1171376011335	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1171376011336	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
1171376011337	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1171376011338	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1171376011339	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1171376011340	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1171376011341	putative active site [active]
1171376011342	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1171376011343	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1171376011344	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1171376011345	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1171376011346	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1171376011347	active site
1171376011348	(T/H)XGH motif; other site
1171376011349	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1171376011350	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1171376011351	DNA binding site [nucleotide binding]
1171376011352	catalytic residue [active]
1171376011353	H2TH interface [polypeptide binding]; other site
1171376011354	putative catalytic residues [active]
1171376011355	turnover-facilitating residue; other site
1171376011356	intercalation triad [nucleotide binding]; other site
1171376011357	8OG recognition residue [nucleotide binding]; other site
1171376011358	putative reading head residues; other site
1171376011359	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1171376011360	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1171376011361	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1171376011362	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1171376011363	hypothetical protein; Reviewed; Region: PRK00024
1171376011364	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1171376011365	MPN+ (JAMM) motif; other site
1171376011366	Zinc-binding site [ion binding]; other site
1171376011367	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1171376011368	Flavoprotein; Region: Flavoprotein; pfam02441
1171376011369	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1171376011370	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1171376011371	trimer interface [polypeptide binding]; other site
1171376011372	active site
1171376011373	division inhibitor protein; Provisional; Region: slmA; PRK09480
1171376011374	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376011375	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1171376011376	active site
1171376011377	ribonuclease PH; Reviewed; Region: rph; PRK00173
1171376011378	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1171376011379	hexamer interface [polypeptide binding]; other site
1171376011380	active site
1171376011381	hypothetical protein; Provisional; Region: PRK11820
1171376011382	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1171376011383	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1171376011384	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376011385	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376011386	dimerization interface [polypeptide binding]; other site
1171376011387	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1171376011388	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1171376011389	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1171376011390	active site
1171376011391	Predicted membrane protein [Function unknown]; Region: COG2860
1171376011392	UPF0126 domain; Region: UPF0126; pfam03458
1171376011393	UPF0126 domain; Region: UPF0126; pfam03458
1171376011394	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1171376011395	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1171376011396	nucleotide binding pocket [chemical binding]; other site
1171376011397	K-X-D-G motif; other site
1171376011398	catalytic site [active]
1171376011399	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1171376011400	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1171376011401	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1171376011402	catalytic site [active]
1171376011403	G-X2-G-X-G-K; other site
1171376011404	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1171376011405	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1171376011406	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1171376011407	Zn2+ binding site [ion binding]; other site
1171376011408	Mg2+ binding site [ion binding]; other site
1171376011409	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1171376011410	synthetase active site [active]
1171376011411	NTP binding site [chemical binding]; other site
1171376011412	metal binding site [ion binding]; metal-binding site
1171376011413	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1171376011414	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1171376011415	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1171376011416	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1171376011417	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1171376011418	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1171376011419	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1171376011420	generic binding surface II; other site
1171376011421	ssDNA binding site; other site
1171376011422	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1171376011423	ATP binding site [chemical binding]; other site
1171376011424	putative Mg++ binding site [ion binding]; other site
1171376011425	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376011426	nucleotide binding region [chemical binding]; other site
1171376011427	ATP-binding site [chemical binding]; other site
1171376011428	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1171376011429	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1171376011430	AsmA family; Region: AsmA; pfam05170
1171376011431	putative alpha-glucosidase; Provisional; Region: PRK10658
1171376011432	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1171376011433	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1171376011434	active site
1171376011435	homotrimer interface [polypeptide binding]; other site
1171376011436	catalytic site [active]
1171376011437	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1171376011438	putative transporter; Provisional; Region: PRK11462
1171376011439	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1171376011440	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376011441	AAA domain; Region: AAA_23; pfam13476
1171376011442	Walker A/P-loop; other site
1171376011443	ATP binding site [chemical binding]; other site
1171376011444	AAA domain; Region: AAA_21; pfam13304
1171376011445	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1171376011446	Virulence protein [General function prediction only]; Region: COG3943
1171376011447	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1171376011448	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1171376011449	Transposase; Region: HTH_Tnp_1; pfam01527
1171376011450	autotransport protein MisL; Provisional; Region: PRK15313
1171376011451	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1171376011452	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1171376011453	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1171376011454	DNA binding site [nucleotide binding]
1171376011455	Isochorismatase family; Region: Isochorismatase; pfam00857
1171376011456	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1171376011457	catalytic triad [active]
1171376011458	dimer interface [polypeptide binding]; other site
1171376011459	conserved cis-peptide bond; other site
1171376011460	magnesium-transporting ATPase; Provisional; Region: PRK15122
1171376011461	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1171376011462	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1171376011463	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1171376011464	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376011465	motif II; other site
1171376011466	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1171376011467	magnesium transport protein MgtC; Provisional; Region: PRK15385
1171376011468	MgtC family; Region: MgtC; pfam02308
1171376011469	EamA-like transporter family; Region: EamA; pfam00892
1171376011470	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1171376011471	EamA-like transporter family; Region: EamA; pfam00892
1171376011472	hypothetical protein; Provisional; Region: PRK09956
1171376011473	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1171376011474	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1171376011475	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1171376011476	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
1171376011477	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1171376011478	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1171376011479	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1171376011480	active site
1171376011481	phosphorylation site [posttranslational modification]
1171376011482	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1171376011483	active pocket/dimerization site; other site
1171376011484	active site
1171376011485	phosphorylation site [posttranslational modification]
1171376011486	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1171376011487	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376011488	Walker A motif; other site
1171376011489	ATP binding site [chemical binding]; other site
1171376011490	Walker B motif; other site
1171376011491	arginine finger; other site
1171376011492	Transcriptional antiterminator [Transcription]; Region: COG3933
1171376011493	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1171376011494	active site
1171376011495	active pocket/dimerization site; other site
1171376011496	phosphorylation site [posttranslational modification]
1171376011497	PRD domain; Region: PRD; pfam00874
1171376011498	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1171376011499	beta-galactosidase; Region: BGL; TIGR03356
1171376011500	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1171376011501	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011502	putative substrate translocation pore; other site
1171376011503	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
1171376011504	Predicted transcriptional regulator [Transcription]; Region: COG2944
1171376011505	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376011506	non-specific DNA binding site [nucleotide binding]; other site
1171376011507	salt bridge; other site
1171376011508	sequence-specific DNA binding site [nucleotide binding]; other site
1171376011509	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1171376011510	dimerization domain swap beta strand [polypeptide binding]; other site
1171376011511	regulatory protein interface [polypeptide binding]; other site
1171376011512	active site
1171376011513	regulatory phosphorylation site [posttranslational modification]; other site
1171376011514	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1171376011515	intersubunit interface [polypeptide binding]; other site
1171376011516	active site
1171376011517	zinc binding site [ion binding]; other site
1171376011518	Na+ binding site [ion binding]; other site
1171376011519	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1171376011520	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
1171376011521	putative N- and C-terminal domain interface [polypeptide binding]; other site
1171376011522	putative active site [active]
1171376011523	putative MgATP binding site [chemical binding]; other site
1171376011524	catalytic site [active]
1171376011525	metal binding site [ion binding]; metal-binding site
1171376011526	putative carbohydrate binding site [chemical binding]; other site
1171376011527	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1171376011528	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1171376011529	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1171376011530	active site
1171376011531	P-loop; other site
1171376011532	phosphorylation site [posttranslational modification]
1171376011533	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376011534	active site
1171376011535	phosphorylation site [posttranslational modification]
1171376011536	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1171376011537	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376011538	DNA-binding site [nucleotide binding]; DNA binding site
1171376011539	UTRA domain; Region: UTRA; pfam07702
1171376011540	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1171376011541	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1171376011542	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011543	putative substrate translocation pore; other site
1171376011544	regulatory protein UhpC; Provisional; Region: PRK11663
1171376011545	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011546	putative substrate translocation pore; other site
1171376011547	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1171376011548	MASE1; Region: MASE1; pfam05231
1171376011549	Histidine kinase; Region: HisKA_3; pfam07730
1171376011550	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376011551	ATP binding site [chemical binding]; other site
1171376011552	Mg2+ binding site [ion binding]; other site
1171376011553	G-X-G motif; other site
1171376011554	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1171376011555	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376011556	active site
1171376011557	phosphorylation site [posttranslational modification]
1171376011558	intermolecular recognition site; other site
1171376011559	dimerization interface [polypeptide binding]; other site
1171376011560	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376011561	DNA binding residues [nucleotide binding]
1171376011562	dimerization interface [polypeptide binding]; other site
1171376011563	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
1171376011564	active site
1171376011565	catalytic residues [active]
1171376011566	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1171376011567	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011568	putative substrate translocation pore; other site
1171376011569	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376011570	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1171376011571	substrate binding site [chemical binding]; other site
1171376011572	dimer interface [polypeptide binding]; other site
1171376011573	ATP binding site [chemical binding]; other site
1171376011574	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1171376011575	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1171376011576	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376011577	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1171376011578	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1171376011579	putative valine binding site [chemical binding]; other site
1171376011580	dimer interface [polypeptide binding]; other site
1171376011581	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1171376011582	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1171376011583	PYR/PP interface [polypeptide binding]; other site
1171376011584	dimer interface [polypeptide binding]; other site
1171376011585	TPP binding site [chemical binding]; other site
1171376011586	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1171376011587	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1171376011588	TPP-binding site [chemical binding]; other site
1171376011589	dimer interface [polypeptide binding]; other site
1171376011590	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1171376011591	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1171376011592	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1171376011593	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011594	putative substrate translocation pore; other site
1171376011595	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1171376011596	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
1171376011597	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376011598	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1171376011599	dimerization interface [polypeptide binding]; other site
1171376011600	substrate binding pocket [chemical binding]; other site
1171376011601	permease DsdX; Provisional; Region: PRK09921
1171376011602	gluconate transporter; Region: gntP; TIGR00791
1171376011603	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1171376011604	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1171376011605	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1171376011606	catalytic residue [active]
1171376011607	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
1171376011608	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
1171376011609	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1171376011610	Predicted membrane protein [Function unknown]; Region: COG2149
1171376011611	putative transporter; Validated; Region: PRK03818
1171376011612	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1171376011613	TrkA-C domain; Region: TrkA_C; pfam02080
1171376011614	TrkA-C domain; Region: TrkA_C; pfam02080
1171376011615	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1171376011616	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1171376011617	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1171376011618	putative dimer interface [polypeptide binding]; other site
1171376011619	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1171376011620	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1171376011621	putative dimer interface [polypeptide binding]; other site
1171376011622	hypothetical protein; Provisional; Region: PRK11616
1171376011623	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1171376011624	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1171376011625	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1171376011626	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1171376011627	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1171376011628	catalytic residues [active]
1171376011629	central insert; other site
1171376011630	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1171376011631	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1171376011632	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1171376011633	heme exporter protein CcmC; Region: ccmC; TIGR01191
1171376011634	heme exporter protein CcmB; Region: ccmB; TIGR01190
1171376011635	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1171376011636	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376011637	Walker A/P-loop; other site
1171376011638	ATP binding site [chemical binding]; other site
1171376011639	Q-loop/lid; other site
1171376011640	ABC transporter signature motif; other site
1171376011641	Walker B; other site
1171376011642	D-loop; other site
1171376011643	H-loop/switch region; other site
1171376011644	Haem-binding domain; Region: Haem_bd; pfam14376
1171376011645	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1171376011646	chaperone protein TorD; Validated; Region: torD; PRK04976
1171376011647	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
1171376011648	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1171376011649	molybdopterin cofactor binding site [chemical binding]; other site
1171376011650	substrate binding site [chemical binding]; other site
1171376011651	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1171376011652	molybdopterin cofactor binding site; other site
1171376011653	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
1171376011654	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1171376011655	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
1171376011656	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376011657	active site
1171376011658	phosphorylation site [posttranslational modification]
1171376011659	intermolecular recognition site; other site
1171376011660	dimerization interface [polypeptide binding]; other site
1171376011661	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376011662	DNA binding site [nucleotide binding]
1171376011663	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
1171376011664	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1171376011665	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
1171376011666	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376011667	dimer interface [polypeptide binding]; other site
1171376011668	phosphorylation site [posttranslational modification]
1171376011669	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376011670	ATP binding site [chemical binding]; other site
1171376011671	Mg2+ binding site [ion binding]; other site
1171376011672	G-X-G motif; other site
1171376011673	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376011674	active site
1171376011675	phosphorylation site [posttranslational modification]
1171376011676	intermolecular recognition site; other site
1171376011677	dimerization interface [polypeptide binding]; other site
1171376011678	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1171376011679	putative binding surface; other site
1171376011680	active site
1171376011681	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011682	D-galactonate transporter; Region: 2A0114; TIGR00893
1171376011683	putative substrate translocation pore; other site
1171376011684	galactonate dehydratase; Provisional; Region: PRK14017
1171376011685	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
1171376011686	putative active site pocket [active]
1171376011687	putative metal binding site [ion binding]; other site
1171376011688	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
1171376011689	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1171376011690	active site
1171376011691	intersubunit interface [polypeptide binding]; other site
1171376011692	catalytic residue [active]
1171376011693	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1171376011694	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
1171376011695	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1171376011696	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376011697	DNA-binding site [nucleotide binding]; DNA binding site
1171376011698	FCD domain; Region: FCD; pfam07729
1171376011699	sugar phosphate phosphatase; Provisional; Region: PRK10513
1171376011700	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376011701	active site
1171376011702	motif I; other site
1171376011703	motif II; other site
1171376011704	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376011705	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011706	D-galactonate transporter; Region: 2A0114; TIGR00893
1171376011707	putative substrate translocation pore; other site
1171376011708	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011709	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1171376011710	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1171376011711	active site pocket [active]
1171376011712	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376011713	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376011714	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1171376011715	putative dimerization interface [polypeptide binding]; other site
1171376011716	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1171376011717	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376011718	Mg2+ binding site [ion binding]; other site
1171376011719	G-X-G motif; other site
1171376011720	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1171376011721	anchoring element; other site
1171376011722	dimer interface [polypeptide binding]; other site
1171376011723	ATP binding site [chemical binding]; other site
1171376011724	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1171376011725	active site
1171376011726	putative metal-binding site [ion binding]; other site
1171376011727	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1171376011728	recF protein; Region: recf; TIGR00611
1171376011729	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376011730	Walker A/P-loop; other site
1171376011731	ATP binding site [chemical binding]; other site
1171376011732	Q-loop/lid; other site
1171376011733	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376011734	ABC transporter signature motif; other site
1171376011735	Walker B; other site
1171376011736	D-loop; other site
1171376011737	H-loop/switch region; other site
1171376011738	DNA polymerase III subunit beta; Validated; Region: PRK05643
1171376011739	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1171376011740	putative DNA binding surface [nucleotide binding]; other site
1171376011741	dimer interface [polypeptide binding]; other site
1171376011742	beta-clamp/clamp loader binding surface; other site
1171376011743	beta-clamp/translesion DNA polymerase binding surface; other site
1171376011744	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1171376011745	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1171376011746	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376011747	Walker A motif; other site
1171376011748	ATP binding site [chemical binding]; other site
1171376011749	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1171376011750	Walker B motif; other site
1171376011751	arginine finger; other site
1171376011752	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1171376011753	DnaA box-binding interface [nucleotide binding]; other site
1171376011754	ent-kaur-16-ene synthase; Region: PLN02279
1171376011755	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1171376011756	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1171376011757	hypothetical protein; Validated; Region: PRK00041
1171376011758	membrane protein insertase; Provisional; Region: PRK01318
1171376011759	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
1171376011760	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1171376011761	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1171376011762	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1171376011763	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1171376011764	G1 box; other site
1171376011765	GTP/Mg2+ binding site [chemical binding]; other site
1171376011766	Switch I region; other site
1171376011767	G2 box; other site
1171376011768	Switch II region; other site
1171376011769	G3 box; other site
1171376011770	G4 box; other site
1171376011771	G5 box; other site
1171376011772	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1171376011773	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1171376011774	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1171376011775	active site
1171376011776	Int/Topo IB signature motif; other site
1171376011777	putative transferase, LIC12162 family; Region: o_ant_LIC12162; TIGR04331
1171376011778	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
1171376011779	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
1171376011780	putative active site [active]
1171376011781	putative NTP binding site [chemical binding]; other site
1171376011782	putative nucleic acid binding site [nucleotide binding]; other site
1171376011783	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1171376011784	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011785	putative substrate translocation pore; other site
1171376011786	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1171376011787	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376011788	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1171376011789	substrate binding pocket [chemical binding]; other site
1171376011790	dimerization interface [polypeptide binding]; other site
1171376011791	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1171376011792	Predicted flavoprotein [General function prediction only]; Region: COG0431
1171376011793	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1171376011794	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1171376011795	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1171376011796	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376011797	active site
1171376011798	motif I; other site
1171376011799	motif II; other site
1171376011800	transcriptional regulator PhoU; Provisional; Region: PRK11115
1171376011801	PhoU domain; Region: PhoU; pfam01895
1171376011802	PhoU domain; Region: PhoU; pfam01895
1171376011803	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1171376011804	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1171376011805	Walker A/P-loop; other site
1171376011806	ATP binding site [chemical binding]; other site
1171376011807	Q-loop/lid; other site
1171376011808	ABC transporter signature motif; other site
1171376011809	Walker B; other site
1171376011810	D-loop; other site
1171376011811	H-loop/switch region; other site
1171376011812	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1171376011813	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376011814	dimer interface [polypeptide binding]; other site
1171376011815	conserved gate region; other site
1171376011816	putative PBP binding loops; other site
1171376011817	ABC-ATPase subunit interface; other site
1171376011818	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1171376011819	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376011820	dimer interface [polypeptide binding]; other site
1171376011821	conserved gate region; other site
1171376011822	putative PBP binding loops; other site
1171376011823	ABC-ATPase subunit interface; other site
1171376011824	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376011825	substrate binding pocket [chemical binding]; other site
1171376011826	membrane-bound complex binding site; other site
1171376011827	hinge residues; other site
1171376011828	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1171376011829	active site
1171376011830	P-loop; other site
1171376011831	phosphorylation site [posttranslational modification]
1171376011832	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1171376011833	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1171376011834	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
1171376011835	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1171376011836	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1171376011837	shikimate binding site; other site
1171376011838	NAD(P) binding site [chemical binding]; other site
1171376011839	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1171376011840	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1171376011841	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1171376011842	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1171376011843	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1171376011844	glutaminase active site [active]
1171376011845	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1171376011846	dimer interface [polypeptide binding]; other site
1171376011847	active site
1171376011848	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1171376011849	dimer interface [polypeptide binding]; other site
1171376011850	active site
1171376011851	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1171376011852	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1171376011853	Substrate binding site; other site
1171376011854	Mg++ binding site; other site
1171376011855	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1171376011856	active site
1171376011857	substrate binding site [chemical binding]; other site
1171376011858	CoA binding site [chemical binding]; other site
1171376011859	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1171376011860	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
1171376011861	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1171376011862	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1171376011863	gamma subunit interface [polypeptide binding]; other site
1171376011864	epsilon subunit interface [polypeptide binding]; other site
1171376011865	LBP interface [polypeptide binding]; other site
1171376011866	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1171376011867	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1171376011868	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1171376011869	alpha subunit interaction interface [polypeptide binding]; other site
1171376011870	Walker A motif; other site
1171376011871	ATP binding site [chemical binding]; other site
1171376011872	Walker B motif; other site
1171376011873	inhibitor binding site; inhibition site
1171376011874	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1171376011875	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1171376011876	core domain interface [polypeptide binding]; other site
1171376011877	delta subunit interface [polypeptide binding]; other site
1171376011878	epsilon subunit interface [polypeptide binding]; other site
1171376011879	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1171376011880	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1171376011881	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1171376011882	beta subunit interaction interface [polypeptide binding]; other site
1171376011883	Walker A motif; other site
1171376011884	ATP binding site [chemical binding]; other site
1171376011885	Walker B motif; other site
1171376011886	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1171376011887	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1171376011888	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1171376011889	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1171376011890	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1171376011891	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1171376011892	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1171376011893	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1171376011894	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1171376011895	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1171376011896	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376011897	S-adenosylmethionine binding site [chemical binding]; other site
1171376011898	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1171376011899	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1171376011900	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1171376011901	FMN-binding protein MioC; Provisional; Region: PRK09004
1171376011902	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1171376011903	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1171376011904	putative DNA binding site [nucleotide binding]; other site
1171376011905	putative Zn2+ binding site [ion binding]; other site
1171376011906	AsnC family; Region: AsnC_trans_reg; pfam01037
1171376011907	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1171376011908	dimer interface [polypeptide binding]; other site
1171376011909	active site
1171376011910	hypothetical protein; Provisional; Region: yieM; PRK10997
1171376011911	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1171376011912	metal ion-dependent adhesion site (MIDAS); other site
1171376011913	regulatory ATPase RavA; Provisional; Region: PRK13531
1171376011914	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376011915	Walker A motif; other site
1171376011916	ATP binding site [chemical binding]; other site
1171376011917	Walker B motif; other site
1171376011918	arginine finger; other site
1171376011919	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1171376011920	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1171376011921	potassium uptake protein; Region: kup; TIGR00794
1171376011922	D-ribose pyranase; Provisional; Region: PRK11797
1171376011923	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1171376011924	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1171376011925	Walker A/P-loop; other site
1171376011926	ATP binding site [chemical binding]; other site
1171376011927	Q-loop/lid; other site
1171376011928	ABC transporter signature motif; other site
1171376011929	Walker B; other site
1171376011930	D-loop; other site
1171376011931	H-loop/switch region; other site
1171376011932	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1171376011933	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1171376011934	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1171376011935	TM-ABC transporter signature motif; other site
1171376011936	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1171376011937	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1171376011938	ligand binding site [chemical binding]; other site
1171376011939	dimerization interface [polypeptide binding]; other site
1171376011940	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376011941	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1171376011942	substrate binding site [chemical binding]; other site
1171376011943	dimer interface [polypeptide binding]; other site
1171376011944	ATP binding site [chemical binding]; other site
1171376011945	transcriptional repressor RbsR; Provisional; Region: PRK10423
1171376011946	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376011947	DNA binding site [nucleotide binding]
1171376011948	domain linker motif; other site
1171376011949	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1171376011950	dimerization interface [polypeptide binding]; other site
1171376011951	ligand binding site [chemical binding]; other site
1171376011952	putative transporter; Provisional; Region: PRK10504
1171376011953	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011954	putative substrate translocation pore; other site
1171376011955	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376011956	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1171376011957	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376011958	DNA-binding site [nucleotide binding]; DNA binding site
1171376011959	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1171376011960	transcriptional regulator HdfR; Provisional; Region: PRK03601
1171376011961	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376011962	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1171376011963	dimerization interface [polypeptide binding]; other site
1171376011964	hypothetical protein; Provisional; Region: PRK11027
1171376011965	putative ATP-dependent protease; Provisional; Region: PRK09862
1171376011966	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1171376011967	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376011968	Walker A motif; other site
1171376011969	ATP binding site [chemical binding]; other site
1171376011970	Walker B motif; other site
1171376011971	arginine finger; other site
1171376011972	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1171376011973	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1171376011974	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1171376011975	PYR/PP interface [polypeptide binding]; other site
1171376011976	dimer interface [polypeptide binding]; other site
1171376011977	TPP binding site [chemical binding]; other site
1171376011978	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1171376011979	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1171376011980	TPP-binding site [chemical binding]; other site
1171376011981	dimer interface [polypeptide binding]; other site
1171376011982	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1171376011983	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1171376011984	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1171376011985	homodimer interface [polypeptide binding]; other site
1171376011986	substrate-cofactor binding pocket; other site
1171376011987	catalytic residue [active]
1171376011988	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1171376011989	threonine dehydratase; Reviewed; Region: PRK09224
1171376011990	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1171376011991	tetramer interface [polypeptide binding]; other site
1171376011992	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376011993	catalytic residue [active]
1171376011994	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1171376011995	putative Ile/Val binding site [chemical binding]; other site
1171376011996	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1171376011997	putative Ile/Val binding site [chemical binding]; other site
1171376011998	Phage-related protein [Function unknown]; Region: COG4679
1171376011999	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
1171376012000	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376012001	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1171376012002	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1171376012003	putative dimerization interface [polypeptide binding]; other site
1171376012004	ketol-acid reductoisomerase; Validated; Region: PRK05225
1171376012005	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1171376012006	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1171376012007	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1171376012008	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1171376012009	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1171376012010	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
1171376012011	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1171376012012	Part of AAA domain; Region: AAA_19; pfam13245
1171376012013	Family description; Region: UvrD_C_2; pfam13538
1171376012014	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1171376012015	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1171376012016	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1171376012017	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1171376012018	ATP binding site [chemical binding]; other site
1171376012019	Mg++ binding site [ion binding]; other site
1171376012020	motif III; other site
1171376012021	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376012022	nucleotide binding region [chemical binding]; other site
1171376012023	ATP-binding site [chemical binding]; other site
1171376012024	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1171376012025	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1171376012026	catalytic residues [active]
1171376012027	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1171376012028	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1171376012029	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1171376012030	RNA binding site [nucleotide binding]; other site
1171376012031	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1171376012032	multimer interface [polypeptide binding]; other site
1171376012033	Walker A motif; other site
1171376012034	ATP binding site [chemical binding]; other site
1171376012035	Walker B motif; other site
1171376012036	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1171376012037	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1171376012038	Mg++ binding site [ion binding]; other site
1171376012039	putative catalytic motif [active]
1171376012040	substrate binding site [chemical binding]; other site
1171376012041	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1171376012042	Chain length determinant protein; Region: Wzz; pfam02706
1171376012043	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1171376012044	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1171376012045	active site
1171376012046	homodimer interface [polypeptide binding]; other site
1171376012047	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1171376012048	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1171376012049	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1171376012050	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
1171376012051	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1171376012052	NAD binding site [chemical binding]; other site
1171376012053	substrate binding site [chemical binding]; other site
1171376012054	homodimer interface [polypeptide binding]; other site
1171376012055	active site
1171376012056	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1171376012057	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1171376012058	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
1171376012059	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1171376012060	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1171376012061	inhibitor-cofactor binding pocket; inhibition site
1171376012062	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376012063	catalytic residue [active]
1171376012064	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1171376012065	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1171376012066	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1171376012067	putative common antigen polymerase; Provisional; Region: PRK02975
1171376012068	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1171376012069	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1171376012070	putative transport protein YifK; Provisional; Region: PRK10746
1171376012071	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1171376012072	HemY protein N-terminus; Region: HemY_N; pfam07219
1171376012073	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1171376012074	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1171376012075	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1171376012076	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1171376012077	active site
1171376012078	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1171376012079	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1171376012080	domain interfaces; other site
1171376012081	active site
1171376012082	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1171376012083	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1171376012084	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1171376012085	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1171376012086	putative iron binding site [ion binding]; other site
1171376012087	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
1171376012088	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1171376012089	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1171376012090	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1171376012091	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1171376012092	hypothetical protein; Provisional; Region: PRK10963
1171376012093	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1171376012094	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1171376012095	active site
1171376012096	Int/Topo IB signature motif; other site
1171376012097	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1171376012098	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376012099	motif II; other site
1171376012100	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1171376012101	Part of AAA domain; Region: AAA_19; pfam13245
1171376012102	Family description; Region: UvrD_C_2; pfam13538
1171376012103	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1171376012104	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1171376012105	Cl binding site [ion binding]; other site
1171376012106	oligomer interface [polypeptide binding]; other site
1171376012107	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
1171376012108	hypothetical protein; Provisional; Region: PRK11371
1171376012109	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1171376012110	EamA-like transporter family; Region: EamA; cl17759
1171376012111	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1171376012112	CoenzymeA binding site [chemical binding]; other site
1171376012113	subunit interaction site [polypeptide binding]; other site
1171376012114	PHB binding site; other site
1171376012115	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1171376012116	dimerization interface [polypeptide binding]; other site
1171376012117	substrate binding site [chemical binding]; other site
1171376012118	active site
1171376012119	calcium binding site [ion binding]; other site
1171376012120	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1171376012121	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1171376012122	ATP binding site [chemical binding]; other site
1171376012123	putative Mg++ binding site [ion binding]; other site
1171376012124	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1171376012125	nucleotide binding region [chemical binding]; other site
1171376012126	ATP-binding site [chemical binding]; other site
1171376012127	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1171376012128	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1171376012129	threonine efflux system; Provisional; Region: PRK10229
1171376012130	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1171376012131	lysophospholipase L2; Provisional; Region: PRK10749
1171376012132	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1171376012133	putative hydrolase; Provisional; Region: PRK10976
1171376012134	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376012135	active site
1171376012136	motif I; other site
1171376012137	motif II; other site
1171376012138	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376012139	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1171376012140	EamA-like transporter family; Region: EamA; pfam00892
1171376012141	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1171376012142	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376012143	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1171376012144	putative dimerization interface [polypeptide binding]; other site
1171376012145	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1171376012146	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1171376012147	THF binding site; other site
1171376012148	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1171376012149	substrate binding site [chemical binding]; other site
1171376012150	THF binding site; other site
1171376012151	zinc-binding site [ion binding]; other site
1171376012152	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1171376012153	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376012154	FeS/SAM binding site; other site
1171376012155	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1171376012156	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1171376012157	uridine phosphorylase; Provisional; Region: PRK11178
1171376012158	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
1171376012159	DNA recombination protein RmuC; Provisional; Region: PRK10361
1171376012160	RmuC family; Region: RmuC; pfam02646
1171376012161	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1171376012162	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376012163	S-adenosylmethionine binding site [chemical binding]; other site
1171376012164	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
1171376012165	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1171376012166	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1171376012167	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1171376012168	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1171376012169	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1171376012170	sec-independent translocase; Provisional; Region: PRK01770
1171376012171	sec-independent translocase; Provisional; Region: tatB; PRK00404
1171376012172	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1171376012173	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1171376012174	active site
1171376012175	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1171376012176	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1171376012177	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
1171376012178	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1171376012179	FMN reductase; Validated; Region: fre; PRK08051
1171376012180	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1171376012181	FAD binding pocket [chemical binding]; other site
1171376012182	FAD binding motif [chemical binding]; other site
1171376012183	phosphate binding motif [ion binding]; other site
1171376012184	beta-alpha-beta structure motif; other site
1171376012185	NAD binding pocket [chemical binding]; other site
1171376012186	potential frameshift: common BLAST hit: gi|383498588|ref|YP_005399277.1| transferase
1171376012187	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1171376012188	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1171376012189	dimer interface [polypeptide binding]; other site
1171376012190	active site
1171376012191	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1171376012192	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1171376012193	substrate binding site [chemical binding]; other site
1171376012194	oxyanion hole (OAH) forming residues; other site
1171376012195	trimer interface [polypeptide binding]; other site
1171376012196	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1171376012197	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1171376012198	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1171376012199	proline dipeptidase; Provisional; Region: PRK13607
1171376012200	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1171376012201	active site
1171376012202	hypothetical protein; Provisional; Region: PRK11568
1171376012203	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1171376012204	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1171376012205	potassium transporter; Provisional; Region: PRK10750
1171376012206	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1171376012207	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1171376012208	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1171376012209	Walker A motif; other site
1171376012210	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1171376012211	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1171376012212	GTP binding site; other site
1171376012213	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1171376012214	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1171376012215	serine/threonine protein kinase; Provisional; Region: PRK11768
1171376012216	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1171376012217	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1171376012218	catalytic residues [active]
1171376012219	hinge region; other site
1171376012220	alpha helical domain; other site
1171376012221	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1171376012222	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1171376012223	putative acyl-acceptor binding pocket; other site
1171376012224	DNA polymerase I; Provisional; Region: PRK05755
1171376012225	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1171376012226	active site
1171376012227	metal binding site 1 [ion binding]; metal-binding site
1171376012228	putative 5' ssDNA interaction site; other site
1171376012229	metal binding site 3; metal-binding site
1171376012230	metal binding site 2 [ion binding]; metal-binding site
1171376012231	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1171376012232	putative DNA binding site [nucleotide binding]; other site
1171376012233	putative metal binding site [ion binding]; other site
1171376012234	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1171376012235	active site
1171376012236	catalytic site [active]
1171376012237	substrate binding site [chemical binding]; other site
1171376012238	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1171376012239	active site
1171376012240	DNA binding site [nucleotide binding]
1171376012241	catalytic site [active]
1171376012242	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1171376012243	G1 box; other site
1171376012244	GTP/Mg2+ binding site [chemical binding]; other site
1171376012245	Switch I region; other site
1171376012246	G2 box; other site
1171376012247	G3 box; other site
1171376012248	Switch II region; other site
1171376012249	G4 box; other site
1171376012250	G5 box; other site
1171376012251	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
1171376012252	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1171376012253	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376012254	FeS/SAM binding site; other site
1171376012255	HemN C-terminal domain; Region: HemN_C; pfam06969
1171376012256	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1171376012257	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376012258	active site
1171376012259	phosphorylation site [posttranslational modification]
1171376012260	intermolecular recognition site; other site
1171376012261	dimerization interface [polypeptide binding]; other site
1171376012262	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376012263	Walker A motif; other site
1171376012264	ATP binding site [chemical binding]; other site
1171376012265	Walker B motif; other site
1171376012266	arginine finger; other site
1171376012267	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1171376012268	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1171376012269	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1171376012270	putative active site [active]
1171376012271	heme pocket [chemical binding]; other site
1171376012272	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376012273	dimer interface [polypeptide binding]; other site
1171376012274	phosphorylation site [posttranslational modification]
1171376012275	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376012276	ATP binding site [chemical binding]; other site
1171376012277	Mg2+ binding site [ion binding]; other site
1171376012278	G-X-G motif; other site
1171376012279	glutamine synthetase; Provisional; Region: glnA; PRK09469
1171376012280	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1171376012281	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1171376012282	GTP-binding protein; Provisional; Region: PRK10218
1171376012283	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1171376012284	G1 box; other site
1171376012285	putative GEF interaction site [polypeptide binding]; other site
1171376012286	GTP/Mg2+ binding site [chemical binding]; other site
1171376012287	Switch I region; other site
1171376012288	G2 box; other site
1171376012289	G3 box; other site
1171376012290	Switch II region; other site
1171376012291	G4 box; other site
1171376012292	G5 box; other site
1171376012293	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1171376012294	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1171376012295	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376012296	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1171376012297	active site
1171376012298	motif I; other site
1171376012299	motif II; other site
1171376012300	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376012301	coproporphyrinogen III oxidase; Validated; Region: PRK08208
1171376012302	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376012303	FeS/SAM binding site; other site
1171376012304	HemN C-terminal domain; Region: HemN_C; pfam06969
1171376012305	Sulfatase; Region: Sulfatase; cl17466
1171376012306	outer membrane porin L; Provisional; Region: ompL; PRK09980
1171376012307	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1171376012308	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376012309	putative substrate translocation pore; other site
1171376012310	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1171376012311	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1171376012312	alpha-glucosidase; Provisional; Region: PRK10426
1171376012313	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1171376012314	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
1171376012315	putative active site [active]
1171376012316	putative catalytic site [active]
1171376012317	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
1171376012318	active site
1171376012319	catalytic residues [active]
1171376012320	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
1171376012321	dimerization interface [polypeptide binding]; other site
1171376012322	putative active cleft [active]
1171376012323	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
1171376012324	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1171376012325	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1171376012326	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376012327	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
1171376012328	substrate binding site [chemical binding]; other site
1171376012329	ATP binding site [chemical binding]; other site
1171376012330	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1171376012331	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1171376012332	putative DNA binding site [nucleotide binding]; other site
1171376012333	putative Zn2+ binding site [ion binding]; other site
1171376012334	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376012335	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1171376012336	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376012337	motif II; other site
1171376012338	hypothetical protein; Reviewed; Region: PRK01637
1171376012339	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1171376012340	putative active site [active]
1171376012341	dimerization interface [polypeptide binding]; other site
1171376012342	putative tRNAtyr binding site [nucleotide binding]; other site
1171376012343	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376012344	Coenzyme A binding pocket [chemical binding]; other site
1171376012345	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1171376012346	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376012347	non-specific DNA binding site [nucleotide binding]; other site
1171376012348	salt bridge; other site
1171376012349	sequence-specific DNA binding site [nucleotide binding]; other site
1171376012350	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
1171376012351	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
1171376012352	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1171376012353	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1171376012354	Predicted transcriptional regulator [Transcription]; Region: COG2944
1171376012355	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376012356	non-specific DNA binding site [nucleotide binding]; other site
1171376012357	salt bridge; other site
1171376012358	sequence-specific DNA binding site [nucleotide binding]; other site
1171376012359	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1171376012360	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1171376012361	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1171376012362	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1171376012363	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1171376012364	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1171376012365	potential frameshift: common BLAST hit: gi|379703280|ref|YP_005245008.1| formate dehydrogenase alpha subunit
1171376012366	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1171376012367	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1171376012368	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1171376012369	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1171376012370	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1171376012371	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376012372	non-specific DNA binding site [nucleotide binding]; other site
1171376012373	salt bridge; other site
1171376012374	sequence-specific DNA binding site [nucleotide binding]; other site
1171376012375	Cupin domain; Region: Cupin_2; cl17218
1171376012376	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1171376012377	lactaldehyde reductase; Region: lactal_redase; TIGR02638
1171376012378	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1171376012379	dimer interface [polypeptide binding]; other site
1171376012380	active site
1171376012381	metal binding site [ion binding]; metal-binding site
1171376012382	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1171376012383	intersubunit interface [polypeptide binding]; other site
1171376012384	active site
1171376012385	Zn2+ binding site [ion binding]; other site
1171376012386	L-rhamnose isomerase; Provisional; Region: PRK01076
1171376012387	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1171376012388	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1171376012389	N- and C-terminal domain interface [polypeptide binding]; other site
1171376012390	active site
1171376012391	putative catalytic site [active]
1171376012392	metal binding site [ion binding]; metal-binding site
1171376012393	ATP binding site [chemical binding]; other site
1171376012394	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1171376012395	carbohydrate binding site [chemical binding]; other site
1171376012396	transcriptional activator RhaS; Provisional; Region: PRK13503
1171376012397	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1171376012398	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376012399	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376012400	transcriptional activator RhaR; Provisional; Region: PRK13502
1171376012401	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1171376012402	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376012403	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
1171376012404	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1171376012405	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1171376012406	DctM-like transporters; Region: DctM; pfam06808
1171376012407	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
1171376012408	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1171376012409	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1171376012410	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1171376012411	superoxide dismutase; Provisional; Region: PRK10925
1171376012412	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1171376012413	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1171376012414	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1171376012415	MOSC domain; Region: MOSC; pfam03473
1171376012416	3-alpha domain; Region: 3-alpha; pfam03475
1171376012417	SnoaL-like domain; Region: SnoaL_2; pfam12680
1171376012418	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1171376012419	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1171376012420	dimerization interface [polypeptide binding]; other site
1171376012421	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376012422	dimer interface [polypeptide binding]; other site
1171376012423	phosphorylation site [posttranslational modification]
1171376012424	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376012425	ATP binding site [chemical binding]; other site
1171376012426	Mg2+ binding site [ion binding]; other site
1171376012427	G-X-G motif; other site
1171376012428	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1171376012429	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376012430	active site
1171376012431	intermolecular recognition site; other site
1171376012432	dimerization interface [polypeptide binding]; other site
1171376012433	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376012434	DNA binding site [nucleotide binding]
1171376012435	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1171376012436	dimer interface [polypeptide binding]; other site
1171376012437	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1171376012438	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1171376012439	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1171376012440	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1171376012441	active site
1171376012442	ADP/pyrophosphate binding site [chemical binding]; other site
1171376012443	dimerization interface [polypeptide binding]; other site
1171376012444	allosteric effector site; other site
1171376012445	fructose-1,6-bisphosphate binding site; other site
1171376012446	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1171376012447	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376012448	substrate binding pocket [chemical binding]; other site
1171376012449	membrane-bound complex binding site; other site
1171376012450	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1171376012451	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1171376012452	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1171376012453	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376012454	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1171376012455	putative substrate binding site [chemical binding]; other site
1171376012456	putative ATP binding site [chemical binding]; other site
1171376012457	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1171376012458	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1171376012459	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376012460	DNA-binding site [nucleotide binding]; DNA binding site
1171376012461	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
1171376012462	UTRA domain; Region: UTRA; pfam07702
1171376012463	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
1171376012464	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1171376012465	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
1171376012466	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
1171376012467	putative N- and C-terminal domain interface [polypeptide binding]; other site
1171376012468	putative active site [active]
1171376012469	putative MgATP binding site [chemical binding]; other site
1171376012470	catalytic site [active]
1171376012471	metal binding site [ion binding]; metal-binding site
1171376012472	putative carbohydrate binding site [chemical binding]; other site
1171376012473	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1171376012474	transcriptional regulator LsrR; Provisional; Region: PRK15418
1171376012475	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1171376012476	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1171376012477	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1171376012478	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1171376012479	Walker A/P-loop; other site
1171376012480	ATP binding site [chemical binding]; other site
1171376012481	Q-loop/lid; other site
1171376012482	ABC transporter signature motif; other site
1171376012483	Walker B; other site
1171376012484	D-loop; other site
1171376012485	H-loop/switch region; other site
1171376012486	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1171376012487	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1171376012488	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1171376012489	TM-ABC transporter signature motif; other site
1171376012490	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1171376012491	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1171376012492	TM-ABC transporter signature motif; other site
1171376012493	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1171376012494	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1171376012495	ligand binding site [chemical binding]; other site
1171376012496	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1171376012497	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1171376012498	putative active site; other site
1171376012499	catalytic residue [active]
1171376012500	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1171376012501	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1171376012502	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1171376012503	substrate binding site [chemical binding]; other site
1171376012504	hexamer interface [polypeptide binding]; other site
1171376012505	metal binding site [ion binding]; metal-binding site
1171376012506	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1171376012507	triosephosphate isomerase; Provisional; Region: PRK14567
1171376012508	substrate binding site [chemical binding]; other site
1171376012509	dimer interface [polypeptide binding]; other site
1171376012510	catalytic triad [active]
1171376012511	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1171376012512	Predicted membrane protein [Function unknown]; Region: COG3152
1171376012513	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1171376012514	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1171376012515	FAD binding pocket [chemical binding]; other site
1171376012516	FAD binding motif [chemical binding]; other site
1171376012517	phosphate binding motif [ion binding]; other site
1171376012518	beta-alpha-beta structure motif; other site
1171376012519	NAD binding pocket [chemical binding]; other site
1171376012520	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1171376012521	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1171376012522	putative active site [active]
1171376012523	glycerol kinase; Provisional; Region: glpK; PRK00047
1171376012524	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1171376012525	N- and C-terminal domain interface [polypeptide binding]; other site
1171376012526	active site
1171376012527	MgATP binding site [chemical binding]; other site
1171376012528	catalytic site [active]
1171376012529	metal binding site [ion binding]; metal-binding site
1171376012530	glycerol binding site [chemical binding]; other site
1171376012531	homotetramer interface [polypeptide binding]; other site
1171376012532	homodimer interface [polypeptide binding]; other site
1171376012533	FBP binding site [chemical binding]; other site
1171376012534	protein IIAGlc interface [polypeptide binding]; other site
1171376012535	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1171376012536	amphipathic channel; other site
1171376012537	Asn-Pro-Ala signature motifs; other site
1171376012538	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1171376012539	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1171376012540	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
1171376012541	UbiA prenyltransferase family; Region: UbiA; pfam01040
1171376012542	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1171376012543	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376012544	Walker A motif; other site
1171376012545	ATP binding site [chemical binding]; other site
1171376012546	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1171376012547	Walker B motif; other site
1171376012548	arginine finger; other site
1171376012549	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1171376012550	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1171376012551	active site
1171376012552	HslU subunit interaction site [polypeptide binding]; other site
1171376012553	essential cell division protein FtsN; Provisional; Region: PRK10927
1171376012554	cell division protein FtsN; Provisional; Region: PRK12757
1171376012555	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376012556	DNA binding site [nucleotide binding]
1171376012557	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1171376012558	domain linker motif; other site
1171376012559	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1171376012560	dimerization interface [polypeptide binding]; other site
1171376012561	ligand binding site [chemical binding]; other site
1171376012562	primosome assembly protein PriA; Validated; Region: PRK05580
1171376012563	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1171376012564	ATP binding site [chemical binding]; other site
1171376012565	putative Mg++ binding site [ion binding]; other site
1171376012566	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1171376012567	ATP-binding site [chemical binding]; other site
1171376012568	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1171376012569	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
1171376012570	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1171376012571	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1171376012572	dimerization interface [polypeptide binding]; other site
1171376012573	DNA binding site [nucleotide binding]
1171376012574	corepressor binding sites; other site
1171376012575	cystathionine gamma-synthase; Provisional; Region: PRK08045
1171376012576	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1171376012577	homodimer interface [polypeptide binding]; other site
1171376012578	substrate-cofactor binding pocket; other site
1171376012579	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376012580	catalytic residue [active]
1171376012581	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1171376012582	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1171376012583	putative catalytic residues [active]
1171376012584	putative nucleotide binding site [chemical binding]; other site
1171376012585	putative aspartate binding site [chemical binding]; other site
1171376012586	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1171376012587	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1171376012588	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1171376012589	mechanosensitive channel MscS; Provisional; Region: PRK10334
1171376012590	Conserved TM helix; Region: TM_helix; pfam05552
1171376012591	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1171376012592	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1171376012593	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1171376012594	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1171376012595	active site
1171376012596	metal binding site [ion binding]; metal-binding site
1171376012597	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1171376012598	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1171376012599	FAD binding site [chemical binding]; other site
1171376012600	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1171376012601	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1171376012602	heme binding site [chemical binding]; other site
1171376012603	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1171376012604	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
1171376012605	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1171376012606	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1171376012607	dimer interface [polypeptide binding]; other site
1171376012608	active site
1171376012609	metal binding site [ion binding]; metal-binding site
1171376012610	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1171376012611	active site
1171376012612	intersubunit interactions; other site
1171376012613	catalytic residue [active]
1171376012614	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1171376012615	dimerization domain swap beta strand [polypeptide binding]; other site
1171376012616	regulatory protein interface [polypeptide binding]; other site
1171376012617	active site
1171376012618	regulatory phosphorylation site [posttranslational modification]; other site
1171376012619	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1171376012620	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1171376012621	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1171376012622	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1171376012623	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376012624	active site
1171376012625	phosphorylation site [posttranslational modification]
1171376012626	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
1171376012627	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1171376012628	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1171376012629	active site
1171376012630	P-loop; other site
1171376012631	phosphorylation site [posttranslational modification]
1171376012632	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
1171376012633	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1171376012634	dimer interface [polypeptide binding]; other site
1171376012635	active site
1171376012636	glycine loop; other site
1171376012637	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376012638	FeS/SAM binding site; other site
1171376012639	pyruvate formate lyase II activase; Provisional; Region: PRK10076
1171376012640	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1171376012641	active site
1171376012642	P-loop; other site
1171376012643	phosphorylation site [posttranslational modification]
1171376012644	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1171376012645	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376012646	hypothetical protein; Provisional; Region: PRK10649
1171376012647	Sulfatase; Region: Sulfatase; pfam00884
1171376012648	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1171376012649	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1171376012650	acetylornithine deacetylase; Provisional; Region: PRK05111
1171376012651	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1171376012652	metal binding site [ion binding]; metal-binding site
1171376012653	putative dimer interface [polypeptide binding]; other site
1171376012654	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1171376012655	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1171376012656	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1171376012657	nucleotide binding site [chemical binding]; other site
1171376012658	N-acetyl-L-glutamate binding site [chemical binding]; other site
1171376012659	argininosuccinate lyase; Provisional; Region: PRK04833
1171376012660	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1171376012661	active sites [active]
1171376012662	tetramer interface [polypeptide binding]; other site
1171376012663	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1171376012664	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376012665	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1171376012666	dimerization interface [polypeptide binding]; other site
1171376012667	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1171376012668	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1171376012669	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1171376012670	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1171376012671	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376012672	hypothetical protein; Provisional; Region: PRK11056
1171376012673	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1171376012674	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
1171376012675	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376012676	S-adenosylmethionine binding site [chemical binding]; other site
1171376012677	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1171376012678	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1171376012679	N-terminal plug; other site
1171376012680	ligand-binding site [chemical binding]; other site
1171376012681	glutamate racemase; Provisional; Region: PRK00865
1171376012682	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1171376012683	FAD binding domain; Region: FAD_binding_4; pfam01565
1171376012684	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1171376012685	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1171376012686	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1171376012687	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1171376012688	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1171376012689	pantothenate kinase; Provisional; Region: PRK05439
1171376012690	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1171376012691	ATP-binding site [chemical binding]; other site
1171376012692	CoA-binding site [chemical binding]; other site
1171376012693	Mg2+-binding site [ion binding]; other site
1171376012694	elongation factor Tu; Reviewed; Region: PRK00049
1171376012695	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1171376012696	G1 box; other site
1171376012697	GEF interaction site [polypeptide binding]; other site
1171376012698	GTP/Mg2+ binding site [chemical binding]; other site
1171376012699	Switch I region; other site
1171376012700	G2 box; other site
1171376012701	G3 box; other site
1171376012702	Switch II region; other site
1171376012703	G4 box; other site
1171376012704	G5 box; other site
1171376012705	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1171376012706	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1171376012707	Antibiotic Binding Site [chemical binding]; other site
1171376012708	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1171376012709	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1171376012710	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1171376012711	putative homodimer interface [polypeptide binding]; other site
1171376012712	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1171376012713	heterodimer interface [polypeptide binding]; other site
1171376012714	homodimer interface [polypeptide binding]; other site
1171376012715	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1171376012716	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1171376012717	23S rRNA interface [nucleotide binding]; other site
1171376012718	L7/L12 interface [polypeptide binding]; other site
1171376012719	putative thiostrepton binding site; other site
1171376012720	L25 interface [polypeptide binding]; other site
1171376012721	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1171376012722	mRNA/rRNA interface [nucleotide binding]; other site
1171376012723	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1171376012724	23S rRNA interface [nucleotide binding]; other site
1171376012725	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1171376012726	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1171376012727	core dimer interface [polypeptide binding]; other site
1171376012728	peripheral dimer interface [polypeptide binding]; other site
1171376012729	L10 interface [polypeptide binding]; other site
1171376012730	L11 interface [polypeptide binding]; other site
1171376012731	putative EF-Tu interaction site [polypeptide binding]; other site
1171376012732	putative EF-G interaction site [polypeptide binding]; other site
1171376012733	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1171376012734	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1171376012735	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1171376012736	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1171376012737	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1171376012738	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1171376012739	RPB3 interaction site [polypeptide binding]; other site
1171376012740	RPB1 interaction site [polypeptide binding]; other site
1171376012741	RPB11 interaction site [polypeptide binding]; other site
1171376012742	RPB10 interaction site [polypeptide binding]; other site
1171376012743	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1171376012744	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1171376012745	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1171376012746	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1171376012747	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1171376012748	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1171376012749	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1171376012750	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1171376012751	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1171376012752	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1171376012753	DNA binding site [nucleotide binding]
1171376012754	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1171376012755	type III secretion system protein; Provisional; Region: PRK15384
1171376012756	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
1171376012757	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1171376012758	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376012759	FeS/SAM binding site; other site
1171376012760	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1171376012761	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1171376012762	ThiS interaction site; other site
1171376012763	putative active site [active]
1171376012764	tetramer interface [polypeptide binding]; other site
1171376012765	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1171376012766	thiS-thiF/thiG interaction site; other site
1171376012767	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1171376012768	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1171376012769	ATP binding site [chemical binding]; other site
1171376012770	substrate interface [chemical binding]; other site
1171376012771	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1171376012772	thiamine phosphate binding site [chemical binding]; other site
1171376012773	active site
1171376012774	pyrophosphate binding site [ion binding]; other site
1171376012775	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1171376012776	ThiC-associated domain; Region: ThiC-associated; pfam13667
1171376012777	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1171376012778	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
1171376012779	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1171376012780	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1171376012781	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1171376012782	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1171376012783	putative NADH binding site [chemical binding]; other site
1171376012784	putative active site [active]
1171376012785	nudix motif; other site
1171376012786	putative metal binding site [ion binding]; other site
1171376012787	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1171376012788	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1171376012789	substrate binding site [chemical binding]; other site
1171376012790	active site
1171376012791	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1171376012792	Active_site [active]
1171376012793	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1171376012794	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1171376012795	IHF dimer interface [polypeptide binding]; other site
1171376012796	IHF - DNA interface [nucleotide binding]; other site
1171376012797	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1171376012798	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1171376012799	dimer interface [polypeptide binding]; other site
1171376012800	sensor protein ZraS; Provisional; Region: PRK10364
1171376012801	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376012802	dimer interface [polypeptide binding]; other site
1171376012803	phosphorylation site [posttranslational modification]
1171376012804	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376012805	ATP binding site [chemical binding]; other site
1171376012806	Mg2+ binding site [ion binding]; other site
1171376012807	G-X-G motif; other site
1171376012808	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
1171376012809	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376012810	active site
1171376012811	phosphorylation site [posttranslational modification]
1171376012812	intermolecular recognition site; other site
1171376012813	dimerization interface [polypeptide binding]; other site
1171376012814	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376012815	Walker A motif; other site
1171376012816	ATP binding site [chemical binding]; other site
1171376012817	Walker B motif; other site
1171376012818	arginine finger; other site
1171376012819	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1171376012820	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1171376012821	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1171376012822	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1171376012823	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1171376012824	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1171376012825	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1171376012826	purine monophosphate binding site [chemical binding]; other site
1171376012827	dimer interface [polypeptide binding]; other site
1171376012828	putative catalytic residues [active]
1171376012829	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1171376012830	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1171376012831	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376012832	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1171376012833	Coenzyme A binding pocket [chemical binding]; other site
1171376012834	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1171376012835	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1171376012836	proposed active site lysine [active]
1171376012837	conserved cys residue [active]
1171376012838	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1171376012839	malate synthase A; Region: malate_syn_A; TIGR01344
1171376012840	active site
1171376012841	isocitrate lyase; Provisional; Region: PRK15063
1171376012842	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1171376012843	tetramer interface [polypeptide binding]; other site
1171376012844	active site
1171376012845	Mg2+/Mn2+ binding site [ion binding]; other site
1171376012846	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1171376012847	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1171376012848	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1171376012849	transcriptional repressor IclR; Provisional; Region: PRK11569
1171376012850	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1171376012851	Bacterial transcriptional regulator; Region: IclR; pfam01614
1171376012852	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1171376012853	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1171376012854	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1171376012855	substrate binding pocket [chemical binding]; other site
1171376012856	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1171376012857	B12 binding site [chemical binding]; other site
1171376012858	cobalt ligand [ion binding]; other site
1171376012859	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1171376012860	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1171376012861	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1171376012862	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1171376012863	active site pocket [active]
1171376012864	oxyanion hole [active]
1171376012865	catalytic triad [active]
1171376012866	active site nucleophile [active]
1171376012867	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1171376012868	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1171376012869	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1171376012870	RNA binding surface [nucleotide binding]; other site
1171376012871	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1171376012872	probable active site [active]
1171376012873	hypothetical protein; Provisional; Region: PRK10515
1171376012874	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1171376012875	Sodium Bile acid symporter family; Region: SBF; pfam01758
1171376012876	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
1171376012877	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1171376012878	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
1171376012879	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1171376012880	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1171376012881	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1171376012882	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1171376012883	Phage-related baseplate assembly protein [General function prediction only]; Region: COG3948
1171376012884	Phage baseplate assembly protein W [General function prediction only]; Region: COG3628
1171376012885	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1171376012886	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1171376012887	Ligand binding site; other site
1171376012888	Putative Catalytic site; other site
1171376012889	DXD motif; other site
1171376012890	Predicted membrane protein [Function unknown]; Region: COG2246
1171376012891	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1171376012892	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1171376012893	Phage protein D [General function prediction only]; Region: COG3500
1171376012894	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1171376012895	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1171376012896	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
1171376012897	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1171376012898	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1171376012899	Phage tail tube protein FII [General function prediction only]; Region: COG3498
1171376012900	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
1171376012901	Gp37 protein; Region: Gp37; pfam09646
1171376012902	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1171376012903	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1171376012904	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1171376012905	catalytic residue [active]
1171376012906	Protein of unknown function (DUF4063); Region: DUF4063; pfam13272
1171376012907	Mor transcription activator family; Region: Mor; pfam08765
1171376012908	aspartate kinase III; Validated; Region: PRK09084
1171376012909	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1171376012910	nucleotide binding site [chemical binding]; other site
1171376012911	substrate binding site [chemical binding]; other site
1171376012912	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1171376012913	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1171376012914	dimer interface [polypeptide binding]; other site
1171376012915	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1171376012916	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1171376012917	active site
1171376012918	dimer interface [polypeptide binding]; other site
1171376012919	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1171376012920	dimer interface [polypeptide binding]; other site
1171376012921	active site
1171376012922	Exopolysaccharide production protein YjbE; Region: YjbE; pfam11106
1171376012923	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1171376012924	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1171376012925	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1171376012926	Predicted membrane protein [Function unknown]; Region: COG3223
1171376012927	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1171376012928	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376012929	dimer interface [polypeptide binding]; other site
1171376012930	conserved gate region; other site
1171376012931	putative PBP binding loops; other site
1171376012932	ABC-ATPase subunit interface; other site
1171376012933	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1171376012934	dimer interface [polypeptide binding]; other site
1171376012935	conserved gate region; other site
1171376012936	putative PBP binding loops; other site
1171376012937	ABC-ATPase subunit interface; other site
1171376012938	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1171376012939	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1171376012940	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1171376012941	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1171376012942	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1171376012943	Walker A/P-loop; other site
1171376012944	ATP binding site [chemical binding]; other site
1171376012945	Q-loop/lid; other site
1171376012946	ABC transporter signature motif; other site
1171376012947	Walker B; other site
1171376012948	D-loop; other site
1171376012949	H-loop/switch region; other site
1171376012950	TOBE domain; Region: TOBE_2; pfam08402
1171376012951	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1171376012952	trimer interface; other site
1171376012953	sugar binding site [chemical binding]; other site
1171376012954	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1171376012955	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1171376012956	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1171376012957	UbiA prenyltransferase family; Region: UbiA; pfam01040
1171376012958	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1171376012959	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1171376012960	putative acyl-acceptor binding pocket; other site
1171376012961	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1171376012962	LexA repressor; Validated; Region: PRK00215
1171376012963	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1171376012964	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1171376012965	Catalytic site [active]
1171376012966	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1171376012967	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1171376012968	hypothetical protein; Provisional; Region: PRK10428
1171376012969	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1171376012970	metal binding site 2 [ion binding]; metal-binding site
1171376012971	putative DNA binding helix; other site
1171376012972	metal binding site 1 [ion binding]; metal-binding site
1171376012973	dimer interface [polypeptide binding]; other site
1171376012974	structural Zn2+ binding site [ion binding]; other site
1171376012975	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1171376012976	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1171376012977	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1171376012978	FMN binding site [chemical binding]; other site
1171376012979	active site
1171376012980	catalytic residues [active]
1171376012981	substrate binding site [chemical binding]; other site
1171376012982	phage shock protein G; Reviewed; Region: pspG; PRK09459
1171376012983	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1171376012984	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1171376012985	NADP binding site [chemical binding]; other site
1171376012986	dimer interface [polypeptide binding]; other site
1171376012987	replicative DNA helicase; Provisional; Region: PRK08006
1171376012988	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1171376012989	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1171376012990	Walker A motif; other site
1171376012991	ATP binding site [chemical binding]; other site
1171376012992	Walker B motif; other site
1171376012993	DNA binding loops [nucleotide binding]
1171376012994	alanine racemase; Reviewed; Region: alr; PRK00053
1171376012995	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1171376012996	active site
1171376012997	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1171376012998	substrate binding site [chemical binding]; other site
1171376012999	catalytic residues [active]
1171376013000	dimer interface [polypeptide binding]; other site
1171376013001	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1171376013002	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1171376013003	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376013004	homodimer interface [polypeptide binding]; other site
1171376013005	catalytic residue [active]
1171376013006	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1171376013007	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376013008	active site
1171376013009	motif I; other site
1171376013010	motif II; other site
1171376013011	Uncharacterized conserved protein [Function unknown]; Region: COG0432
1171376013012	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1171376013013	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1171376013014	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1171376013015	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1171376013016	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1171376013017	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1171376013018	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1171376013019	dimer interface [polypeptide binding]; other site
1171376013020	ssDNA binding site [nucleotide binding]; other site
1171376013021	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1171376013022	hypothetical protein; Validated; Region: PRK09039
1171376013023	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
1171376013024	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1171376013025	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1171376013026	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1171376013027	HlyD family secretion protein; Region: HlyD_3; pfam13437
1171376013028	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1171376013029	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013030	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013031	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013032	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013033	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013034	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1171376013035	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1171376013036	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013037	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1171376013038	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1171376013039	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013040	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1171376013041	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013042	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1171376013043	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1171376013044	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013045	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1171376013046	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013047	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1171376013048	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1171376013049	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013050	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1171376013051	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1171376013052	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013053	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1171376013054	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013055	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013056	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1171376013057	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013058	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013059	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013060	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013061	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013062	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1171376013063	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013064	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1171376013065	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013066	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
1171376013067	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013068	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1171376013069	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1171376013070	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376013071	Walker A/P-loop; other site
1171376013072	ATP binding site [chemical binding]; other site
1171376013073	Q-loop/lid; other site
1171376013074	ABC transporter signature motif; other site
1171376013075	Walker B; other site
1171376013076	D-loop; other site
1171376013077	H-loop/switch region; other site
1171376013078	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1171376013079	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1171376013080	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376013081	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1171376013082	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376013083	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1171376013084	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1171376013085	DNA binding residues [nucleotide binding]
1171376013086	dimer interface [polypeptide binding]; other site
1171376013087	[2Fe-2S] cluster binding site [ion binding]; other site
1171376013088	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1171376013089	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1171376013090	putative C-terminal domain interface [polypeptide binding]; other site
1171376013091	putative GSH binding site (G-site) [chemical binding]; other site
1171376013092	putative dimer interface [polypeptide binding]; other site
1171376013093	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
1171376013094	putative N-terminal domain interface [polypeptide binding]; other site
1171376013095	putative dimer interface [polypeptide binding]; other site
1171376013096	putative substrate binding pocket (H-site) [chemical binding]; other site
1171376013097	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1171376013098	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1171376013099	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1171376013100	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1171376013101	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376013102	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1171376013103	putative dimerization interface [polypeptide binding]; other site
1171376013104	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1171376013105	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1171376013106	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1171376013107	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1171376013108	Na binding site [ion binding]; other site
1171376013109	Predicted membrane protein [Function unknown]; Region: COG3162
1171376013110	acetyl-CoA synthetase; Provisional; Region: PRK00174
1171376013111	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1171376013112	active site
1171376013113	CoA binding site [chemical binding]; other site
1171376013114	acyl-activating enzyme (AAE) consensus motif; other site
1171376013115	AMP binding site [chemical binding]; other site
1171376013116	acetate binding site [chemical binding]; other site
1171376013117	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1171376013118	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
1171376013119	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1171376013120	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
1171376013121	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1171376013122	heme lyase subunit NrfE; Provisional; Region: PRK10369
1171376013123	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
1171376013124	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1171376013125	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1171376013126	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1171376013127	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1171376013128	Sel1-like repeats; Region: SEL1; smart00671
1171376013129	potential frameshift: common BLAST hit: gi|378986960|ref|YP_005250116.1| formate dehydrogenase alpha subunit
1171376013130	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
1171376013131	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376013132	Coenzyme A binding pocket [chemical binding]; other site
1171376013133	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1171376013134	dimer interface [polypeptide binding]; other site
1171376013135	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1171376013136	hypothetical protein; Provisional; Region: PRK10220
1171376013137	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1171376013138	PhnA protein; Region: PhnA; pfam03831
1171376013139	proline/glycine betaine transporter; Provisional; Region: PRK10642
1171376013140	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376013141	putative substrate translocation pore; other site
1171376013142	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1171376013143	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1171376013144	HAMP domain; Region: HAMP; pfam00672
1171376013145	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376013146	dimer interface [polypeptide binding]; other site
1171376013147	phosphorylation site [posttranslational modification]
1171376013148	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376013149	ATP binding site [chemical binding]; other site
1171376013150	Mg2+ binding site [ion binding]; other site
1171376013151	G-X-G motif; other site
1171376013152	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1171376013153	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376013154	active site
1171376013155	phosphorylation site [posttranslational modification]
1171376013156	intermolecular recognition site; other site
1171376013157	dimerization interface [polypeptide binding]; other site
1171376013158	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376013159	DNA binding site [nucleotide binding]
1171376013160	putative metal dependent hydrolase; Provisional; Region: PRK11598
1171376013161	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1171376013162	Sulfatase; Region: Sulfatase; pfam00884
1171376013163	arginine:agmatin antiporter; Provisional; Region: PRK10644
1171376013164	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
1171376013165	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376013166	arginine decarboxylase; Provisional; Region: PRK15029
1171376013167	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1171376013168	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1171376013169	homodimer interface [polypeptide binding]; other site
1171376013170	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1171376013171	catalytic residue [active]
1171376013172	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1171376013173	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
1171376013174	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376013175	alpha-galactosidase; Provisional; Region: PRK15076
1171376013176	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1171376013177	NAD binding site [chemical binding]; other site
1171376013178	sugar binding site [chemical binding]; other site
1171376013179	divalent metal binding site [ion binding]; other site
1171376013180	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1171376013181	dimer interface [polypeptide binding]; other site
1171376013182	melibiose:sodium symporter; Provisional; Region: PRK10429
1171376013183	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1171376013184	fumarate hydratase; Provisional; Region: PRK15389
1171376013185	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1171376013186	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1171376013187	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1171376013188	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1171376013189	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1171376013190	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376013191	active site
1171376013192	phosphorylation site [posttranslational modification]
1171376013193	intermolecular recognition site; other site
1171376013194	dimerization interface [polypeptide binding]; other site
1171376013195	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1171376013196	PAS domain; Region: PAS; smart00091
1171376013197	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376013198	ATP binding site [chemical binding]; other site
1171376013199	Mg2+ binding site [ion binding]; other site
1171376013200	G-X-G motif; other site
1171376013201	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1171376013202	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1171376013203	putative [Fe4-S4] binding site [ion binding]; other site
1171376013204	putative molybdopterin cofactor binding site [chemical binding]; other site
1171376013205	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1171376013206	putative molybdopterin cofactor binding site; other site
1171376013207	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1171376013208	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1171376013209	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1171376013210	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
1171376013211	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1171376013212	SdiA-regulated; Region: SdiA-regulated; cd09971
1171376013213	putative active site [active]
1171376013214	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1171376013215	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1171376013216	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376013217	DNA binding residues [nucleotide binding]
1171376013218	dimerization interface [polypeptide binding]; other site
1171376013219	AraC family transcriptional regulator; Provisional; Region: PRK15186
1171376013220	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1171376013221	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376013222	Coenzyme A binding pocket [chemical binding]; other site
1171376013223	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1171376013224	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1171376013225	active site
1171376013226	EthD domain; Region: EthD; pfam07110
1171376013227	Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg3; cd01282
1171376013228	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1171376013229	DNA binding residues [nucleotide binding]
1171376013230	putative dimer interface [polypeptide binding]; other site
1171376013231	putative transcriptional regulator; Provisional; Region: PRK11640
1171376013232	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1171376013233	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1171376013234	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1171376013235	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1171376013236	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1171376013237	DsbD alpha interface [polypeptide binding]; other site
1171376013238	catalytic residues [active]
1171376013239	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1171376013240	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1171376013241	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1171376013242	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1171376013243	Aspartase; Region: Aspartase; cd01357
1171376013244	active sites [active]
1171376013245	tetramer interface [polypeptide binding]; other site
1171376013246	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1171376013247	putative transporter; Provisional; Region: PRK11021
1171376013248	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1171376013249	oligomerisation interface [polypeptide binding]; other site
1171376013250	mobile loop; other site
1171376013251	roof hairpin; other site
1171376013252	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1171376013253	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1171376013254	ring oligomerisation interface [polypeptide binding]; other site
1171376013255	ATP/Mg binding site [chemical binding]; other site
1171376013256	stacking interactions; other site
1171376013257	hinge regions; other site
1171376013258	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1171376013259	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1171376013260	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376013261	FeS/SAM binding site; other site
1171376013262	elongation factor P; Validated; Region: PRK00529
1171376013263	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1171376013264	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1171376013265	RNA binding site [nucleotide binding]; other site
1171376013266	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1171376013267	RNA binding site [nucleotide binding]; other site
1171376013268	Predicted small secreted protein [Function unknown]; Region: COG5510
1171376013269	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
1171376013270	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1171376013271	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376013272	DNA binding residues [nucleotide binding]
1171376013273	dimerization interface [polypeptide binding]; other site
1171376013274	multidrug efflux system protein; Provisional; Region: PRK11431
1171376013275	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1171376013276	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1171376013277	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1171376013278	Iron-sulfur protein interface; other site
1171376013279	proximal quinone binding site [chemical binding]; other site
1171376013280	C-subunit interface; other site
1171376013281	distal quinone binding site; other site
1171376013282	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1171376013283	D-subunit interface [polypeptide binding]; other site
1171376013284	Iron-sulfur protein interface; other site
1171376013285	proximal quinone binding site [chemical binding]; other site
1171376013286	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1171376013287	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1171376013288	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1171376013289	L-aspartate oxidase; Provisional; Region: PRK06175
1171376013290	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1171376013291	poxB regulator PoxA; Provisional; Region: PRK09350
1171376013292	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1171376013293	motif 1; other site
1171376013294	dimer interface [polypeptide binding]; other site
1171376013295	active site
1171376013296	motif 2; other site
1171376013297	motif 3; other site
1171376013298	inner membrane transporter YjeM; Provisional; Region: PRK15238
1171376013299	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
1171376013300	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1171376013301	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1171376013302	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1171376013303	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1171376013304	GTPase RsgA; Reviewed; Region: PRK12288
1171376013305	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1171376013306	RNA binding site [nucleotide binding]; other site
1171376013307	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1171376013308	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1171376013309	GTP/Mg2+ binding site [chemical binding]; other site
1171376013310	G4 box; other site
1171376013311	G5 box; other site
1171376013312	G1 box; other site
1171376013313	Switch I region; other site
1171376013314	G2 box; other site
1171376013315	G3 box; other site
1171376013316	Switch II region; other site
1171376013317	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1171376013318	catalytic site [active]
1171376013319	putative active site [active]
1171376013320	putative substrate binding site [chemical binding]; other site
1171376013321	dimer interface [polypeptide binding]; other site
1171376013322	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1171376013323	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1171376013324	substrate binding pocket [chemical binding]; other site
1171376013325	membrane-bound complex binding site; other site
1171376013326	hinge residues; other site
1171376013327	epoxyqueuosine reductase; Region: TIGR00276
1171376013328	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1171376013329	putative carbohydrate kinase; Provisional; Region: PRK10565
1171376013330	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1171376013331	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1171376013332	putative substrate binding site [chemical binding]; other site
1171376013333	putative ATP binding site [chemical binding]; other site
1171376013334	ADP-binding protein; Provisional; Region: PRK10646
1171376013335	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1171376013336	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1171376013337	active site
1171376013338	metal binding site [ion binding]; metal-binding site
1171376013339	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1171376013340	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376013341	ATP binding site [chemical binding]; other site
1171376013342	Mg2+ binding site [ion binding]; other site
1171376013343	G-X-G motif; other site
1171376013344	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1171376013345	ATP binding site [chemical binding]; other site
1171376013346	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1171376013347	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1171376013348	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1171376013349	bacterial Hfq-like; Region: Hfq; cd01716
1171376013350	hexamer interface [polypeptide binding]; other site
1171376013351	Sm1 motif; other site
1171376013352	RNA binding site [nucleotide binding]; other site
1171376013353	Sm2 motif; other site
1171376013354	GTPase HflX; Provisional; Region: PRK11058
1171376013355	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1171376013356	HflX GTPase family; Region: HflX; cd01878
1171376013357	G1 box; other site
1171376013358	GTP/Mg2+ binding site [chemical binding]; other site
1171376013359	Switch I region; other site
1171376013360	G2 box; other site
1171376013361	G3 box; other site
1171376013362	Switch II region; other site
1171376013363	G4 box; other site
1171376013364	G5 box; other site
1171376013365	FtsH protease regulator HflK; Provisional; Region: PRK10930
1171376013366	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1171376013367	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1171376013368	FtsH protease regulator HflC; Provisional; Region: PRK11029
1171376013369	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1171376013370	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1171376013371	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1171376013372	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1171376013373	GDP-binding site [chemical binding]; other site
1171376013374	ACT binding site; other site
1171376013375	IMP binding site; other site
1171376013376	Predicted transcriptional regulator [Transcription]; Region: COG1959
1171376013377	transcriptional repressor NsrR; Provisional; Region: PRK11014
1171376013378	exoribonuclease R; Provisional; Region: PRK11642
1171376013379	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1171376013380	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1171376013381	RNB domain; Region: RNB; pfam00773
1171376013382	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1171376013383	RNA binding site [nucleotide binding]; other site
1171376013384	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1171376013385	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1171376013386	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1171376013387	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3789
1171376013388	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1171376013389	Ion channel; Region: Ion_trans_2; pfam07885
1171376013390	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
1171376013391	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
1171376013392	Predicted membrane protein [Function unknown]; Region: COG3766
1171376013393	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1171376013394	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1171376013395	Predicted integral membrane protein [Function unknown]; Region: COG5463
1171376013396	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1171376013397	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1171376013398	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1171376013399	FAD binding site [chemical binding]; other site
1171376013400	substrate binding site [chemical binding]; other site
1171376013401	catalytic residues [active]
1171376013402	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1171376013403	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1171376013404	esterase; Provisional; Region: PRK10566
1171376013405	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1171376013406	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1171376013407	transcriptional repressor UlaR; Provisional; Region: PRK13509
1171376013408	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1171376013409	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1171376013410	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1171376013411	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1171376013412	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1171376013413	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1171376013414	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1171376013415	active site
1171376013416	P-loop; other site
1171376013417	phosphorylation site [posttranslational modification]
1171376013418	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376013419	active site
1171376013420	phosphorylation site [posttranslational modification]
1171376013421	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1171376013422	active site
1171376013423	dimer interface [polypeptide binding]; other site
1171376013424	magnesium binding site [ion binding]; other site
1171376013425	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1171376013426	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1171376013427	AP (apurinic/apyrimidinic) site pocket; other site
1171376013428	DNA interaction; other site
1171376013429	Metal-binding active site; metal-binding site
1171376013430	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1171376013431	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1171376013432	intersubunit interface [polypeptide binding]; other site
1171376013433	active site
1171376013434	Zn2+ binding site [ion binding]; other site
1171376013435	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1171376013436	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1171376013437	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1171376013438	dimer interface [polypeptide binding]; other site
1171376013439	ssDNA binding site [nucleotide binding]; other site
1171376013440	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1171376013441	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1171376013442	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1171376013443	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1171376013444	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1171376013445	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1171376013446	EamA-like transporter family; Region: EamA; pfam00892
1171376013447	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1171376013448	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1171376013449	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1171376013450	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1171376013451	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1171376013452	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1171376013453	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1171376013454	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1171376013455	Hemerythrin-like domain; Region: Hr-like; cd12108
1171376013456	Fe binding site [ion binding]; other site
1171376013457	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1171376013458	EamA-like transporter family; Region: EamA; pfam00892
1171376013459	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1171376013460	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1171376013461	NADP binding site [chemical binding]; other site
1171376013462	Predicted transcriptional regulators [Transcription]; Region: COG1733
1171376013463	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1171376013464	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1171376013465	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1171376013466	active site
1171376013467	metal binding site [ion binding]; metal-binding site
1171376013468	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1171376013469	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1171376013470	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1171376013471	active site
1171376013472	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
1171376013473	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1171376013474	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1171376013475	Domain of unknown function DUF21; Region: DUF21; pfam01595
1171376013476	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1171376013477	Transporter associated domain; Region: CorC_HlyC; smart01091
1171376013478	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1171376013479	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1171376013480	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1171376013481	Surface antigen; Region: Bac_surface_Ag; pfam01103
1171376013482	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1171376013483	Family of unknown function (DUF490); Region: DUF490; pfam04357
1171376013484	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1171376013485	putative active site pocket [active]
1171376013486	dimerization interface [polypeptide binding]; other site
1171376013487	putative catalytic residue [active]
1171376013488	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376013489	D-galactonate transporter; Region: 2A0114; TIGR00893
1171376013490	putative substrate translocation pore; other site
1171376013491	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
1171376013492	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1171376013493	active site
1171376013494	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1171376013495	dimer interface [polypeptide binding]; other site
1171376013496	substrate binding site [chemical binding]; other site
1171376013497	metal binding sites [ion binding]; metal-binding site
1171376013498	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1171376013499	AMP binding site [chemical binding]; other site
1171376013500	metal binding site [ion binding]; metal-binding site
1171376013501	active site
1171376013502	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1171376013503	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1171376013504	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1171376013505	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1171376013506	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1171376013507	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1171376013508	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1171376013509	putative active site [active]
1171376013510	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1171376013511	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376013512	putative substrate translocation pore; other site
1171376013513	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376013514	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1171376013515	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376013516	putative substrate translocation pore; other site
1171376013517	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376013518	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
1171376013519	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1171376013520	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1171376013521	tetrameric interface [polypeptide binding]; other site
1171376013522	NAD binding site [chemical binding]; other site
1171376013523	catalytic residues [active]
1171376013524	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1171376013525	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1171376013526	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376013527	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1171376013528	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1171376013529	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1171376013530	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1171376013531	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
1171376013532	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
1171376013533	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1171376013534	major facilitator superfamily transporter; Provisional; Region: PRK05122
1171376013535	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376013536	putative substrate translocation pore; other site
1171376013537	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1171376013538	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1171376013539	substrate binding site [chemical binding]; other site
1171376013540	ATP binding site [chemical binding]; other site
1171376013541	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
1171376013542	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
1171376013543	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
1171376013544	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1171376013545	PYR/PP interface [polypeptide binding]; other site
1171376013546	dimer interface [polypeptide binding]; other site
1171376013547	TPP binding site [chemical binding]; other site
1171376013548	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1171376013549	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
1171376013550	TPP-binding site; other site
1171376013551	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1171376013552	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1171376013553	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1171376013554	polyol permease family; Region: 2A0118; TIGR00897
1171376013555	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376013556	putative substrate translocation pore; other site
1171376013557	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
1171376013558	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1171376013559	DNA interaction; other site
1171376013560	Metal-binding active site; metal-binding site
1171376013561	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1171376013562	hypothetical protein; Provisional; Region: PRK05255
1171376013563	peptidase PmbA; Provisional; Region: PRK11040
1171376013564	cytochrome b562; Provisional; Region: PRK15058
1171376013565	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1171376013566	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
1171376013567	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
1171376013568	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1171376013569	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
1171376013570	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
1171376013571	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1171376013572	active site
1171376013573	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1171376013574	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1171376013575	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1171376013576	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1171376013577	HTH domain; Region: HTH_11; pfam08279
1171376013578	Mga helix-turn-helix domain; Region: Mga; pfam05043
1171376013579	PRD domain; Region: PRD; pfam00874
1171376013580	PRD domain; Region: PRD; pfam00874
1171376013581	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1171376013582	active site
1171376013583	P-loop; other site
1171376013584	phosphorylation site [posttranslational modification]
1171376013585	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1171376013586	active site
1171376013587	phosphorylation site [posttranslational modification]
1171376013588	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
1171376013589	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1171376013590	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1171376013591	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376013592	FeS/SAM binding site; other site
1171376013593	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1171376013594	ATP cone domain; Region: ATP-cone; pfam03477
1171376013595	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1171376013596	effector binding site; other site
1171376013597	active site
1171376013598	Zn binding site [ion binding]; other site
1171376013599	glycine loop; other site
1171376013600	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1171376013601	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1171376013602	Ca binding site [ion binding]; other site
1171376013603	active site
1171376013604	catalytic site [active]
1171376013605	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1171376013606	trehalose repressor; Provisional; Region: treR; PRK09492
1171376013607	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376013608	DNA binding site [nucleotide binding]
1171376013609	domain linker motif; other site
1171376013610	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1171376013611	dimerization interface [polypeptide binding]; other site
1171376013612	ligand binding site [chemical binding]; other site
1171376013613	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1171376013614	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1171376013615	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1171376013616	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1171376013617	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1171376013618	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1171376013619	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1171376013620	Transposase; Region: HTH_Tnp_1; cl17663
1171376013621	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1171376013622	homotrimer interaction site [polypeptide binding]; other site
1171376013623	putative active site [active]
1171376013624	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1171376013625	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1171376013626	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1171376013627	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1171376013628	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1171376013629	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1171376013630	pyrBI operon leader peptide; Provisional; Region: PRK10224
1171376013631	Arginine repressor [Transcription]; Region: ArgR; COG1438
1171376013632	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1171376013633	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1171376013634	Predicted membrane protein [Function unknown]; Region: COG1288
1171376013635	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1171376013636	ornithine carbamoyltransferase; Validated; Region: PRK02102
1171376013637	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1171376013638	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1171376013639	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1171376013640	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1171376013641	putative substrate binding site [chemical binding]; other site
1171376013642	nucleotide binding site [chemical binding]; other site
1171376013643	nucleotide binding site [chemical binding]; other site
1171376013644	homodimer interface [polypeptide binding]; other site
1171376013645	arginine deiminase; Provisional; Region: PRK01388
1171376013646	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1171376013647	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1171376013648	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1171376013649	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1171376013650	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
1171376013651	RNase E inhibitor protein; Provisional; Region: PRK11191
1171376013652	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1171376013653	active site
1171376013654	dinuclear metal binding site [ion binding]; other site
1171376013655	dimerization interface [polypeptide binding]; other site
1171376013656	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
1171376013657	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1171376013658	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376013659	Coenzyme A binding pocket [chemical binding]; other site
1171376013660	Predicted membrane protein [Function unknown]; Region: COG4269
1171376013661	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1171376013662	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1171376013663	HIGH motif; other site
1171376013664	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1171376013665	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1171376013666	active site
1171376013667	KMSKS motif; other site
1171376013668	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1171376013669	tRNA binding surface [nucleotide binding]; other site
1171376013670	anticodon binding site; other site
1171376013671	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1171376013672	DNA polymerase III subunit chi; Validated; Region: PRK05728
1171376013673	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1171376013674	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1171376013675	interface (dimer of trimers) [polypeptide binding]; other site
1171376013676	Substrate-binding/catalytic site; other site
1171376013677	Zn-binding sites [ion binding]; other site
1171376013678	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1171376013679	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1171376013680	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1171376013681	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1171376013682	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1171376013683	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1171376013684	DNA binding site [nucleotide binding]
1171376013685	domain linker motif; other site
1171376013686	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1171376013687	putative dimerization interface [polypeptide binding]; other site
1171376013688	putative ligand binding site [chemical binding]; other site
1171376013689	gluconate transporter; Region: gntP; TIGR00791
1171376013690	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1171376013691	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
1171376013692	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1171376013693	NADP binding site [chemical binding]; other site
1171376013694	homodimer interface [polypeptide binding]; other site
1171376013695	active site
1171376013696	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1171376013697	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1171376013698	putative NAD(P) binding site [chemical binding]; other site
1171376013699	catalytic Zn binding site [ion binding]; other site
1171376013700	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1171376013701	ATP-binding site [chemical binding]; other site
1171376013702	Gluconate-6-phosphate binding site [chemical binding]; other site
1171376013703	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1171376013704	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1171376013705	putative NAD(P) binding site [chemical binding]; other site
1171376013706	putative substrate binding site [chemical binding]; other site
1171376013707	catalytic Zn binding site [ion binding]; other site
1171376013708	structural Zn binding site [ion binding]; other site
1171376013709	dimer interface [polypeptide binding]; other site
1171376013710	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1171376013711	Part of AAA domain; Region: AAA_19; pfam13245
1171376013712	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1171376013713	AAA domain; Region: AAA_12; pfam13087
1171376013714	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1171376013715	putative active site [active]
1171376013716	catalytic site [active]
1171376013717	Uncharacterized conserved protein [Function unknown]; Region: COG4127
1171376013718	Restriction endonuclease; Region: Mrr_cat; pfam04471
1171376013719	conserved hypothetical protein; Region: Lon_rel_chp; TIGR02653
1171376013720	Putative ATP-dependent Lon protease; Region: Lon_2; pfam13337
1171376013721	TIGR02687 family protein; Region: TIGR02687
1171376013722	PglZ domain; Region: PglZ; pfam08665
1171376013723	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376013724	AAA domain; Region: AAA_21; pfam13304
1171376013725	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1171376013726	Walker A/P-loop; other site
1171376013727	Walker A/P-loop; other site
1171376013728	ATP binding site [chemical binding]; other site
1171376013729	ATP binding site [chemical binding]; other site
1171376013730	Q-loop/lid; other site
1171376013731	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
1171376013732	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1171376013733	TIGR02680 family protein; Region: TIGR02680
1171376013734	Domain of unknown function (DUF1788); Region: DUF1788; pfam08747
1171376013735	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
1171376013736	hypothetical protein; Provisional; Region: PRK12378
1171376013737	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1171376013738	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376013739	S-adenosylmethionine binding site [chemical binding]; other site
1171376013740	hypothetical protein; Provisional; Region: PRK13687
1171376013741	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4332
1171376013742	Protein of unknown function DUF91; Region: DUF91; cl00709
1171376013743	Uncharacterized conserved protein [Function unknown]; Region: COG3439
1171376013744	Dienelactone hydrolase family; Region: DLH; pfam01738
1171376013745	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1171376013746	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1171376013747	DNA-binding site [nucleotide binding]; DNA binding site
1171376013748	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1171376013749	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1171376013750	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1171376013751	active site
1171376013752	HIGH motif; other site
1171376013753	dimer interface [polypeptide binding]; other site
1171376013754	KMSKS motif; other site
1171376013755	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1171376013756	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
1171376013757	aspartate racemase; Region: asp_race; TIGR00035
1171376013758	cell density-dependent motility repressor; Provisional; Region: PRK10082
1171376013759	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1171376013760	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1171376013761	dimerization interface [polypeptide binding]; other site
1171376013762	isoaspartyl dipeptidase; Provisional; Region: PRK10657
1171376013763	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1171376013764	active site
1171376013765	hypothetical protein; Provisional; Region: PRK10519
1171376013766	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1171376013767	Nucleoside recognition; Region: Gate; pfam07670
1171376013768	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
1171376013769	Predicted membrane protein [Function unknown]; Region: COG2733
1171376013770	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
1171376013771	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376013772	putative substrate translocation pore; other site
1171376013773	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1171376013774	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1171376013775	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1171376013776	NAD(P) binding site [chemical binding]; other site
1171376013777	catalytic residues [active]
1171376013778	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
1171376013779	endoribonuclease SymE; Provisional; Region: PRK13605
1171376013780	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
1171376013781	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1171376013782	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1171376013783	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1171376013784	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1171376013785	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1171376013786	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
1171376013787	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
1171376013788	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1171376013789	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1171376013790	ATP binding site [chemical binding]; other site
1171376013791	putative Mg++ binding site [ion binding]; other site
1171376013792	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
1171376013793	Mrr N-terminal domain; Region: Mrr_N; pfam14338
1171376013794	Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; Region: CH; cl00030
1171376013795	Restriction endonuclease; Region: Mrr_cat; pfam04471
1171376013796	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
1171376013797	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
1171376013798	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1171376013799	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1171376013800	P-loop, Walker A motif; other site
1171376013801	Base recognition motif; other site
1171376013802	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1171376013803	Uncharacterized small protein [Function unknown]; Region: COG2879
1171376013804	carbon starvation protein A; Provisional; Region: PRK15015
1171376013805	Carbon starvation protein CstA; Region: CstA; pfam02554
1171376013806	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1171376013807	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1171376013808	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376013809	Walker A motif; other site
1171376013810	ATP binding site [chemical binding]; other site
1171376013811	Walker B motif; other site
1171376013812	arginine finger; other site
1171376013813	Transcriptional antiterminator [Transcription]; Region: COG3933
1171376013814	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1171376013815	active pocket/dimerization site; other site
1171376013816	active site
1171376013817	phosphorylation site [posttranslational modification]
1171376013818	PRD domain; Region: PRD; pfam00874
1171376013819	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1171376013820	active pocket/dimerization site; other site
1171376013821	active site
1171376013822	phosphorylation site [posttranslational modification]
1171376013823	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1171376013824	active site
1171376013825	phosphorylation site [posttranslational modification]
1171376013826	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1171376013827	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1171376013828	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1171376013829	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1171376013830	dimer interface [polypeptide binding]; other site
1171376013831	active site
1171376013832	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1171376013833	dimer interface [polypeptide binding]; other site
1171376013834	active site
1171376013835	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1171376013836	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1171376013837	putative active site [active]
1171376013838	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1171376013839	phosphoglycerol transferase I; Provisional; Region: PRK03776
1171376013840	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1171376013841	hypothetical protein; Provisional; Region: PRK11667
1171376013842	DNA replication protein DnaC; Validated; Region: PRK07952
1171376013843	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1171376013844	Walker A motif; other site
1171376013845	ATP binding site [chemical binding]; other site
1171376013846	Walker B motif; other site
1171376013847	primosomal protein DnaI; Provisional; Region: PRK02854
1171376013848	hypothetical protein; Provisional; Region: PRK09917
1171376013849	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1171376013850	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1171376013851	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1171376013852	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376013853	DNA binding residues [nucleotide binding]
1171376013854	dimerization interface [polypeptide binding]; other site
1171376013855	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1171376013856	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376013857	DNA binding residues [nucleotide binding]
1171376013858	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1171376013859	putative deacylase active site [active]
1171376013860	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1171376013861	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1171376013862	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1171376013863	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1171376013864	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376013865	metal binding site [ion binding]; metal-binding site
1171376013866	active site
1171376013867	I-site; other site
1171376013868	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1171376013869	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1171376013870	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1171376013871	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1171376013872	S-adenosylmethionine binding site [chemical binding]; other site
1171376013873	DNA polymerase III subunit psi; Validated; Region: PRK06856
1171376013874	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1171376013875	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376013876	Coenzyme A binding pocket [chemical binding]; other site
1171376013877	dUMP phosphatase; Provisional; Region: PRK09449
1171376013878	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376013879	motif II; other site
1171376013880	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1171376013881	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1171376013882	G1 box; other site
1171376013883	putative GEF interaction site [polypeptide binding]; other site
1171376013884	GTP/Mg2+ binding site [chemical binding]; other site
1171376013885	Switch I region; other site
1171376013886	G2 box; other site
1171376013887	G3 box; other site
1171376013888	Switch II region; other site
1171376013889	G4 box; other site
1171376013890	G5 box; other site
1171376013891	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1171376013892	periplasmic protein; Provisional; Region: PRK10568
1171376013893	BON domain; Region: BON; pfam04972
1171376013894	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1171376013895	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1171376013896	active site
1171376013897	nucleophile elbow; other site
1171376013898	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1171376013899	active site
1171376013900	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
1171376013901	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1171376013902	FeS/SAM binding site; other site
1171376013903	hypothetical protein; Provisional; Region: PRK10977
1171376013904	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1171376013905	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1171376013906	intersubunit interface [polypeptide binding]; other site
1171376013907	active site
1171376013908	catalytic residue [active]
1171376013909	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1171376013910	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1171376013911	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1171376013912	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1171376013913	phosphopentomutase; Provisional; Region: PRK05362
1171376013914	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1171376013915	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1171376013916	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1171376013917	hypothetical protein; Provisional; Region: PRK15301
1171376013918	putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304
1171376013919	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376013920	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376013921	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376013922	putative fimbrial chaperone protein; Provisional; Region: PRK09918
1171376013923	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376013924	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376013925	hypothetical protein; Provisional; Region: PRK15302
1171376013926	hypothetical protein; Provisional; Region: PRK15303
1171376013927	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1171376013928	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1171376013929	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1171376013930	hypothetical protein; Provisional; Region: PRK11246
1171376013931	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1171376013932	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1171376013933	motif II; other site
1171376013934	DNA repair protein RadA; Region: sms; TIGR00416
1171376013935	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1171376013936	Walker A motif/ATP binding site; other site
1171376013937	ATP binding site [chemical binding]; other site
1171376013938	Walker B motif; other site
1171376013939	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1171376013940	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1171376013941	non-specific DNA binding site [nucleotide binding]; other site
1171376013942	salt bridge; other site
1171376013943	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1171376013944	sequence-specific DNA binding site [nucleotide binding]; other site
1171376013945	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1171376013946	active site
1171376013947	(T/H)XGH motif; other site
1171376013948	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1171376013949	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1171376013950	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1171376013951	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1171376013952	ABC transporter; Region: ABC_tran_2; pfam12848
1171376013953	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1171376013954	lytic murein transglycosylase; Provisional; Region: PRK11619
1171376013955	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1171376013956	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1171376013957	catalytic residue [active]
1171376013958	Trp operon repressor; Provisional; Region: PRK01381
1171376013959	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1171376013960	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1171376013961	catalytic core [active]
1171376013962	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1171376013963	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376013964	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1171376013965	hypothetical protein; Provisional; Region: PRK10756
1171376013966	CreA protein; Region: CreA; pfam05981
1171376013967	DNA-binding response regulator CreB; Provisional; Region: PRK11083
1171376013968	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376013969	active site
1171376013970	phosphorylation site [posttranslational modification]
1171376013971	intermolecular recognition site; other site
1171376013972	dimerization interface [polypeptide binding]; other site
1171376013973	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376013974	DNA binding site [nucleotide binding]
1171376013975	sensory histidine kinase CreC; Provisional; Region: PRK11100
1171376013976	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1171376013977	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1171376013978	dimer interface [polypeptide binding]; other site
1171376013979	phosphorylation site [posttranslational modification]
1171376013980	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1171376013981	ATP binding site [chemical binding]; other site
1171376013982	Mg2+ binding site [ion binding]; other site
1171376013983	G-X-G motif; other site
1171376013984	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
1171376013985	putative major fimbrial protein SthE; Provisional; Region: PRK15292
1171376013986	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1171376013987	putative fimbrial protein SthD; Provisional; Region: PRK15293
1171376013988	putative fimbrial outer membrane usher protein SthC; Provisional; Region: PRK15294
1171376013989	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376013990	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376013991	PapC C-terminal domain; Region: PapC_C; pfam13953
1171376013992	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
1171376013993	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376013994	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376013995	putative fimbrial protein SthA; Provisional; Region: PRK15296
1171376013996	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1171376013997	Helix-turn-helix domain; Region: HTH_36; pfam13730
1171376013998	two-component response regulator; Provisional; Region: PRK11173
1171376013999	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1171376014000	active site
1171376014001	phosphorylation site [posttranslational modification]
1171376014002	intermolecular recognition site; other site
1171376014003	dimerization interface [polypeptide binding]; other site
1171376014004	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1171376014005	DNA binding site [nucleotide binding]
1171376014006	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1171376014007	putative RNA methyltransferase; Provisional; Region: PRK10433
1171376014008	putative transposase; Provisional; Region: PRK09857
1171376014009	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1171376014010	Antirestriction protein (ArdA); Region: ArdA; pfam07275
1171376014011	PsiA protein; Region: PsiA; cl11646
1171376014012	plasmid SOS inhibition protein B; Provisional; Region: psiB; PRK13701
1171376014013	ParB-like nuclease domain; Region: ParBc; pfam02195
1171376014014	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1171376014015	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1171376014016	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1171376014017	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1171376014018	dimer interface [polypeptide binding]; other site
1171376014019	ssDNA binding site [nucleotide binding]; other site
1171376014020	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1171376014021	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
1171376014022	Antirestriction protein; Region: Antirestrict; pfam03230
1171376014023	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
1171376014024	putative methylase; Provisional; Region: PRK13699
1171376014025	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1171376014026	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
1171376014027	DinI-like family; Region: DinI; pfam06183
1171376014028	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1171376014029	Catalytic site [active]
1171376014030	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1171376014031	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1171376014032	active site
1171376014033	DNA binding site [nucleotide binding]
1171376014034	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1171376014035	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
1171376014036	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
1171376014037	Mg binding site [ion binding]; other site
1171376014038	nucleotide binding site [chemical binding]; other site
1171376014039	putative protofilament interface [polypeptide binding]; other site
1171376014040	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1171376014041	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1171376014042	P-loop; other site
1171376014043	Magnesium ion binding site [ion binding]; other site
1171376014044	Phage integrase family; Region: Phage_integrase; pfam00589
1171376014045	active site
1171376014046	DNA binding site [nucleotide binding]
1171376014047	Int/Topo IB signature motif; other site
1171376014048	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1171376014049	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1171376014050	Adhesin biosynthesis transcription regulatory protein; Region: PapB; pfam03333
1171376014051	fimbrial protein PefA; Provisional; Region: PRK15214
1171376014052	fimbrial outer membrane usher protein PefC; Provisional; Region: PRK15213
1171376014053	PapC N-terminal domain; Region: PapC_N; pfam13954
1171376014054	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1171376014055	fimbrial chaperone protein PefD; Provisional; Region: PRK15211
1171376014056	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1171376014057	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1171376014058	FaeA-like protein; Region: FaeA; pfam04703
1171376014059	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1171376014060	DNA binding residues [nucleotide binding]
1171376014061	dimerization interface [polypeptide binding]; other site
1171376014062	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1171376014063	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1171376014064	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1171376014065	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1171376014066	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1171376014067	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1171376014068	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1171376014069	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1171376014070	Transposase; Region: HTH_Tnp_1; pfam01527
1171376014071	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1171376014072	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1171376014073	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1171376014074	catalytic residues [active]
1171376014075	hinge region; other site
1171376014076	alpha helical domain; other site
1171376014077	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1171376014078	SdiA-regulated; Region: SdiA-regulated; cd09971
1171376014079	putative active site [active]
1171376014080	resistance to complement killing; Provisional; Region: PRK15240
1171376014081	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1171376014082	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1171376014083	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1171376014084	SdiA-regulated; Region: SdiA-regulated; cd09971
1171376014085	replication protein; Provisional; Region: PRK13750
1171376014086	RepA leader peptide Tap; Provisional; Region: PRK14745
1171376014087	replication protein; Provisional; Region: PRK13702
1171376014088	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
1171376014089	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1171376014090	putative active site [active]
1171376014091	catalytic site [active]
1171376014092	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1171376014093	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
1171376014094	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
1171376014095	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
1171376014096	putative kissing complex interaction region; other site
1171376014097	putative RNA binding sites [nucleotide binding]; other site
1171376014098	conjugal transfer pilus acetylation protein TraX; Provisional; Region: PRK13706
1171376014099	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK13709
1171376014100	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
1171376014101	AAA domain; Region: AAA_30; pfam13604
1171376014102	DNA helicase TraI; Region: TraI; pfam07057
1171376014103	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1171376014104	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1171376014105	oligomeric interface; other site
1171376014106	putative active site [active]
1171376014107	homodimer interface [polypeptide binding]; other site
1171376014108	type IV conjugative transfer system coupling protein TraD; Region: TraD_Ftype; TIGR02759
1171376014109	F sex factor protein N terminal; Region: TraD_N; pfam12615
1171376014110	Bacterial conjugation protein TrwB,  ATP binding domain. TrwB is a homohexamer encoded by conjugative plasmids in Gram-negative bacteria. TrwB also has an all alpha domain which has been hypothesized to be responsible for DNA binding. TrwB is a component...; Region: TrwB; cd01127
1171376014111	multimer interface [polypeptide binding]; other site
1171376014112	Walker A motif; other site
1171376014113	ATP binding site [chemical binding]; other site
1171376014114	Walker B motif; other site
1171376014115	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
1171376014116	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
1171376014117	Plasmid conjugative transfer entry exclusion protein TraS; Region: TraS; pfam10624
1171376014118	conjugal transfer mating pair stabilization protein TraG; Provisional; Region: PRK13735
1171376014119	conjugal transfer pilus assembly protein TraH; Provisional; Region: PRK13723
1171376014120	conjugal transfer protein TrbB; Provisional; Region: PRK13728
1171376014121	conjugal transfer pilin chaperone TraQ; Provisional; Region: PRK13727
1171376014122	conjugal pilus assembly protein TraF; Provisional; Region: PRK13703
1171376014123	F plasmid transfer operon protein; Region: TraF; pfam13728
1171376014124	Conjugal transfer protein TrbE; Region: TrbE; cl10142
1171376014125	conjugal transfer mating pair stabilization protein TraN; Reviewed; Region: PRK12355
1171376014126	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1171376014127	active site
1171376014128	conjugal transfer pilus assembly protein TrbC; Provisional; Region: PRK13730
1171376014129	conjugal transfer pilus assembly protein TraU; Provisional; Region: PRK13737
1171376014130	conjugal transfer pilus assembly protein TraW; Provisional; Region: PRK13738
1171376014131	conjugal transfer protein TrbI; Provisional; Region: PRK13717
1171376014132	conjugal transfer ATP-binding protein TraC; Provisional; Region: PRK13721
1171376014133	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
1171376014134	Domain of unknown function DUF87; Region: DUF87; pfam01935
1171376014135	conjugal transfer protein TraR; Provisional; Region: PRK13715
1171376014136	conjugal transfer protein TraV; Provisional; Region: PRK13733
1171376014137	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
1171376014138	conjugal transfer protein TrbD; Provisional; Region: PRK13724
1171376014139	NTPase; Region: NTPase_1; cl17478
1171376014140	TraP protein; Region: TraP; pfam07296
1171376014141	conjugal transfer pilus assembly protein TraB; Provisional; Region: PRK13729
1171376014142	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
1171376014143	conjugal transfer protein TraK; Provisional; Region: PRK13736
1171376014144	TraK protein; Region: TraK; pfam06586
1171376014145	conjugal transfer pilus assembly protein TraE; Provisional; Region: PRK13726
1171376014146	conjugal transfer pilus assembly protein TraL; Provisional; Region: PRK13707
1171376014147	conjugal transfer pilin subunit TraA; Provisional; Region: PRK13734
1171376014148	conjugal transfer protein TraY; Provisional; Region: PRK13740
1171376014149	conjugal transfer transcriptional regulator TraJ; Provisional; Region: PRK13719
1171376014150	conjugal transfer protein TraM; Provisional; Region: PRK13713
1171376014151	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1171376014152	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1171376014153	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1171376014154	catalytic residue [active]
1171376014155	Domain of unknown function (DUF932); Region: DUF932; cl12129
1171376014156	Domain of unknown function (DUF932); Region: DUF932; cl12129
1171376014157	Domain of unknown function (DUF932); Region: DUF932; cl12129
1171376014158	PsiA protein; Region: PsiA; pfam06952
1171376014159	Plasmid SOS inhibition protein (PsiB); Region: PsiB; pfam06290
1171376014160	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1171376014161	ParB-like nuclease domain; Region: ParBc; pfam02195
1171376014162	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1171376014163	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1171376014164	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1171376014165	dimer interface [polypeptide binding]; other site
1171376014166	ssDNA binding site [nucleotide binding]; other site
1171376014167	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1171376014168	DNA polymerase III, theta subunit; Region: DNA_pol3_theta; pfam06440
1171376014169	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
1171376014170	Antirestriction protein; Region: Antirestrict; pfam03230
1171376014171	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
1171376014172	putative methylase; Provisional; Region: PRK13699
1171376014173	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1171376014174	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1171376014175	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1171376014176	Catalytic site [active]
1171376014177	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1171376014178	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1171376014179	active site
1171376014180	DNA binding site [nucleotide binding]
1171376014181	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1171376014182	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1171376014183	ParB-like nuclease domain; Region: ParBc; pfam02195
1171376014184	ParB family; Region: ParB; pfam08775
1171376014185	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1171376014186	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1171376014187	P-loop; other site
1171376014188	Magnesium ion binding site [ion binding]; other site
1171376014189	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1171376014190	Magnesium ion binding site [ion binding]; other site
1171376014191	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1171376014192	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1171376014193	Protein of unknown function (DUF2913); Region: DUF2913; pfam11140
1171376014194	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1171376014195	catalytic site [active]
1171376014196	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1171376014197	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
1171376014198	active site clefts [active]
1171376014199	zinc binding site [ion binding]; other site
1171376014200	dimer interface [polypeptide binding]; other site
1171376014201	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1171376014202	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1171376014203	Integrase core domain; Region: rve; pfam00665
1171376014204	H+ Antiporter protein; Region: 2A0121; TIGR00900
1171376014205	short chain dehydrogenase; Provisional; Region: PRK08263
1171376014206	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1171376014207	NADP binding site [chemical binding]; other site
1171376014208	active site
1171376014209	steroid binding site; other site
1171376014210	Uncharacterized protein family (UPF0157); Region: UPF0157; cl00987
1171376014211	dihydropteroate synthase; Region: DHPS; TIGR01496
1171376014212	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1171376014213	substrate binding pocket [chemical binding]; other site
1171376014214	dimer interface [polypeptide binding]; other site
1171376014215	inhibitor binding site; inhibition site
1171376014216	MULE transposase domain; Region: MULE; pfam10551
1171376014217	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1171376014218	aminoglycoside resistance protein; Provisional; Region: PRK13746
1171376014219	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1171376014220	active site
1171376014221	NTP binding site [chemical binding]; other site
1171376014222	metal binding triad [ion binding]; metal-binding site
1171376014223	antibiotic binding site [chemical binding]; other site
1171376014224	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1171376014225	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1171376014226	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376014227	putative substrate translocation pore; other site
1171376014228	aminoglycoside resistance protein; Provisional; Region: PRK13746
1171376014229	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1171376014230	active site
1171376014231	NTP binding site [chemical binding]; other site
1171376014232	metal binding triad [ion binding]; metal-binding site
1171376014233	antibiotic binding site [chemical binding]; other site
1171376014234	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1171376014235	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1171376014236	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1171376014237	folate binding site [chemical binding]; other site
1171376014238	NADP+ binding site [chemical binding]; other site
1171376014239	integrase/recombinase; Provisional; Region: PRK15417
1171376014240	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
1171376014241	Int/Topo IB signature motif; other site
1171376014242	valyl-tRNA synthetase-like protein; Provisional; Region: PTZ00419
1171376014243	Domain of unknown function (DUF3330); Region: DUF3330; pfam11809
1171376014244	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1171376014245	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1171376014246	catalytic residues [active]
1171376014247	catalytic nucleophile [active]
1171376014248	Presynaptic Site I dimer interface [polypeptide binding]; other site
1171376014249	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1171376014250	Synaptic Flat tetramer interface [polypeptide binding]; other site
1171376014251	Synaptic Site I dimer interface [polypeptide binding]; other site
1171376014252	DNA binding site [nucleotide binding]
1171376014253	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1171376014254	DNA-binding interface [nucleotide binding]; DNA binding site
1171376014255	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
1171376014256	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
1171376014257	Predicted nucleotide-binding protein containing TIR-like domain; Region: TIR-like; pfam10137
1171376014258	Protein of unknown function (DUF4238); Region: DUF4238; pfam14022
1171376014259	Phage terminase small subunit; Region: Phage_terminase; pfam10668
1171376014260	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
1171376014261	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
1171376014262	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1171376014263	active site
1171376014264	catalytic residues [active]
1171376014265	DNA binding site [nucleotide binding]
1171376014266	Int/Topo IB signature motif; other site
1171376014267	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1171376014268	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
1171376014269	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1171376014270	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1171376014271	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1171376014272	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1171376014273	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1171376014274	virulence protein SpvD; Provisional; Region: PRK15250
1171376014275	Salmonella virulence-associated 28kDa protein; Region: VRP3; cl04142
1171376014276	virulence protein SpvB; Provisional; Region: PRK15244
1171376014277	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
1171376014278	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
1171376014279	active site
1171376014280	conformational flexibility of ligand binding pocket; other site
1171376014281	ADP-ribosylating toxin turn-turn motif; other site
1171376014282	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1171376014283	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1171376014284	Integrase core domain; Region: rve; pfam00665
1171376014285	Helix-turn-helix domain of resolvase; Region: HTH_7; pfam02796
1171376014286	beta-lactamase TEM; Provisional; Region: PRK15442
1171376014287	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
1171376014288	Hok/gef family; Region: HOK_GEF; pfam01848
1171376014289	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1171376014290	dimerization domain [polypeptide binding]; other site
1171376014291	dimer interface [polypeptide binding]; other site
1171376014292	catalytic residues [active]
1171376014293	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
1171376014294	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1171376014295	conjugal transfer relaxosome component TraJ; Provisional; Region: PRK13877
1171376014296	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1171376014297	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1171376014298	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
1171376014299	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1171376014300	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
1171376014301	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1171376014302	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
1171376014303	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1171376014304	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
1171376014305	Transposase; Region: HTH_Tnp_1; pfam01527
1171376014306	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1171376014307	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1171376014308	salt bridge; other site
1171376014309	non-specific DNA binding site [nucleotide binding]; other site
1171376014310	sequence-specific DNA binding site [nucleotide binding]; other site
1171376014311	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1171376014312	MobA/MobL family; Region: MobA_MobL; pfam03389
1171376014313	AAA domain; Region: AAA_25; pfam13481
1171376014314	Hexameric Replicative Helicase RepA.  RepA is encoded by a plasmid, which is found in most Gram negative bacteria. RepA is a 5'-3' DNA helicase which can utilize ATP, GTP and CTP to a lesser extent; Region: repA; cd01125
1171376014315	Walker A motif; other site
1171376014316	NTP binding site [chemical binding]; other site
1171376014317	hexamer interface [polypeptide binding]; other site
1171376014318	Walker B motif; other site
1171376014319	Replication protein C (RepC); Region: RepC; pfam06504
1171376014320	dihydropteroate synthase; Region: DHPS; TIGR01496
1171376014321	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1171376014322	substrate binding pocket [chemical binding]; other site
1171376014323	dimer interface [polypeptide binding]; other site
1171376014324	inhibitor binding site; inhibition site
1171376014325	Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150
1171376014326	Phosphotransferase enzyme family; Region: APH; pfam01636
1171376014327	active site
1171376014328	ATP binding site [chemical binding]; other site
1171376014329	antibiotic binding site [chemical binding]; other site
1171376014330	Aminoglycoside/hydroxyurea antibiotic resistance kinase; Region: APH_6_hur; pfam04655
1171376014331	potential frameshift: common BLAST hit: gi|431805260|ref|YP_007232162.1| tetracycline repressor protein
1171376014332	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1171376014333	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1171376014334	putative substrate translocation pore; other site
1171376014335	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1171376014336	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1171376014337	Coenzyme A binding pocket [chemical binding]; other site
1171376014338	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
1171376014339	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
1171376014340	MbeB-like, N-term conserved region; Region: MbeB_N; pfam04837
1171376014341	MbeD/MobD like; Region: MbeD_MobD; pfam04899
1171376014342	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1171376014343	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1171376014344	metal binding site [ion binding]; metal-binding site
1171376014345	active site
1171376014346	I-site; other site